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https://www.readbyqxmd.com/read/29148112/big-data-and-data-science-in-healthcare-what-nurses-and-midwives-need-to-know
#1
EDITORIAL
Siobhan O'Connor
The evolution of technology in contemporary society has been accelerating in recent decades, with smaller, more interconnected hardware devices and software applications becoming the norm. As desktop computing paved the way for mobile platforms, which are now transitioning to wearable devices and other sensors, it is inevitable these electronic tools will advance into the realm of nanotechnology and biotechnology in the years to come. As the proliferation of information and communication technology continues it has led to a tsunami of digital data (Bates et al, 2014), which is being collected on many aspects of life...
November 17, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29142812/left-ventricle-relative-apical-sparing-in-cardiac-amyloidosis
#2
Marianna Nardozza, Elisabetta Chiodi, Donato Mele
Amyloidosis is a disease characterized by the extracellular deposition of the protein amyloid. It is a multiorgan disease, and cardiac involvement is not uncommon, generally in the form of a restrictive cardiomyopathy. Typical aspects of cardiac amyloidosis have been described at echocardiography and magnetic resonance imaging (MRI). In particular, the relative apical sparing at two-dimensional speckle-tracking echocardiography has been reported to be specific for cardiac amyloidosis. In our case, we report for the first time that this echocardiographic sign is related to lack of hyperenhancement at late gadolinium enhancement imaging in cardiac MRI...
October 2017: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29139538/limitations-of-the-pax7-creer-t2-transgene-for-driving-deletion-of-nf1-in-adult-mouse-muscle
#3
Matthew A Summers, Kathy Mikulec, Lauren Peacock, David G Little, Aaron Schindeler
Neurofibromatosis Type 1 (NF1) is an autosomal dominant genetic disorder that results in a variety of characteristic manifestations. Prior studies have shown reduced muscle size and global skeletal muscle weakness in children with NF1. This associated weakness can lead to significant challenges impacting on quality of life. Pre-clinical studies using a muscle-specific NF1 knockout mouse have linked this weakness to an underlying primary metabolic deficiency in the muscle. However, the neonatal lethality of this strain prevents analysis of the role of NF1 in adult muscle...
2017: International Journal of Developmental Biology
https://www.readbyqxmd.com/read/29133657/revisiting-the-tram-track-sign
#4
Akshay Gopinathan Nair, Veena R Iyer, Indumati Gopinathan
No abstract text is available yet for this article.
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29128392/adrenergic-manipulation-inhibits-pavlovian-conditioned-approach-behaviors
#5
Kyle Z Pasquariello, Marina Han, Cagla Unal, Paul J Meyer
Environmental rewards and Pavlovian reward cues can acquire incentive salience, thereby eliciting incentive motivational states and instigate reward-seeking. In rats, the incentive salience of food cues can be measured during a Pavlovian conditioned approach paradigm, in which rats engage in cue-directed approach ("sign-tracking") or approach the food delivery location ("goal-tracking"). While it has been shown that dopamine signaling is necessary for sign-tracking, some studies have suggested that norepinephrine is involved in learning to sign-track as well...
November 8, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29121945/potential-dosimetric-benefits-of-adaptive-tumor-tracking-over-the-internal-target-volume-concept-for-stereotactic-body-radiation-therapy-of-pancreatic-cancer
#6
Konstantina Karava, Stefanie Ehrbar, Oliver Riesterer, Johannes Roesch, Stefan Glatz, Stephan Klöck, Matthias Guckenberger, Stephanie Tanadini-Lang
BACKGROUND: Radiotherapy for pancreatic cancer has two major challenges: (I) the tumor is adjacent to several critical organs and, (II) the mobility of both, the tumor and its surrounding organs at risk (OARs). A treatment planning study simulating stereotactic body radiation therapy (SBRT) for pancreatic tumors with both the internal target volume (ITV) concept and the tumor tracking approach was performed. The two respiratory motion-management techniques were compared in terms of doses to the target volume and organs at risk...
November 9, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/29112741/atherosclerosis-as-a-potential-pitfall-in-the-diagnosis-of-giant-cell-arteritis
#7
Eugenio De Miguel, Luis M Beltran, Irene Monjo, Francesco Deodati, Wolfgang A Schmidt, Juan Garcia-Puig
Objectives: To explore whether the increase in the intima-media thickness (IMT) in arteriosclerotic disease correlates with the increase in the IMT in temporal arteries (TAs) and if that could mimic the US GCA halo sign. Methods: Consecutive patients ⩾50 years old with high vascular risk and without signs or symptoms of GCA were included. The carotid US IMT measurements were obtained using a standardized software radiofrequency-tracking technology. Colour Doppler US and grey-scale measurements of the IMT in the branches of both TAs were performed by a second sonographer using a 22 MHz probe...
November 2, 2017: Rheumatology
https://www.readbyqxmd.com/read/29110092/tracking-posttraumatic-hemianopia
#8
Thomas Decramer, Karel Van Keer, Peter Stalmans, Patrick Dupont, Stefan Sunaert, Tom Theys
Hemianopia after traumatic brain injury is not infrequent and results from retro-chiasmatic lesions. Differentiating optic pathway lesions can be challenging with classic imaging. Advanced imaging techniques as an investigational tool for posttraumatic hemianopia are discussed and their pitfalls highlighted through an illustrative case study. In a patient with posttraumatic hemianopia, MRI at 8 weeks and 2 years after trauma were analyzed. Diffusion tensor imaging (DTI) and morphometric analysis of the primary visual cortex (V1) were performed...
November 6, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/29106754/right-heart-function-in-impaired-left-ventricular-diastolic-function-2d-speckle-tracking-echocardiography-based-and-doppler-tissue-imaging-based-analysis-of-right-atrial-and-ventricular-function
#9
Anna Brand, Marny Bathe, Sabine Oertelt-Prigione, Ute Seeland, Mirjam Rücke, Vera Regitz-Zagrosek, Karl Stangl, Fabian Knebel, Verena Stangl, Henryk Dreger
AIM: The aim of our study was to describe right atrial (RA) and right ventricular (RV) function, assessed by Doppler tissue imaging and 2D speckle tracking echocardiography (2DSTE), in women with signs of early impaired left ventricular diastolic function (DD). METHODS AND RESULTS: In a cross-sectional trial, standard parameters of diastolic and right heart function were investigated in 438 women of the Berlin Female Risk Evaluation (BEFRI) study. In a subset of women, average peak systolic RA strain (RAS), as well as the average peak systolic RV strain of the free wall (RVS free wall) and of all RV segments (average RV strain; RVS Avg), was analyzed using 2DSTE...
November 6, 2017: Echocardiography
https://www.readbyqxmd.com/read/29105955/right-ventricular-systolic-function-and-mechanical-dispersion-identify-patients-with-arrhythmogenic-right-ventricular-cardiomyopathy
#10
Meriam Åström Aneq, Eva Maret, Lars Brudin, Anneli Svensson, Jan Engvall
PURPOSE: To assess right ventricular (RV) regional and global systolic function using feature tracking (FT) in patients with a definite diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC) and to investigate if changes in strain amplitude and mechanical dispersion indicate a propensity for arrhythmia. MATERIALS AND METHODS: Twenty-seven patients fulfilling Task Force Criteria for ARVC and 24 healthy volunteers underwent MR at 1·5 Tesla. Steady-state free precession cine of long-axis slices and a short-axis stack of the RV was acquired...
November 6, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29094536/undertaking-an-accurate-and-comprehensive-assessment-of-the-acutely-ill-adult
#11
Paula Mayo
Accurate assessment of the acutely ill adult who has recently been admitted to hospital, or an inpatient whose condition begins to deteriorate, is becoming a required skill for nurses as people live longer and with a variety of complex conditions, and as nursing skills continue to evolve and develop. This article emphasises the importance of undertaking an accurate and comprehensive patient assessment to ensure that management strategies are implemented in a timely manner. The article also considers the importance of the National Early Warning Score (NEWS), which is a 'track-and-trigger' tool designed to identify patients who are at risk of deterioration...
October 18, 2017: Nursing Standard
https://www.readbyqxmd.com/read/29082079/robust-tracking-of-respiratory-rate-in-high-dynamic-range-scenes-using-mobile-thermal-imaging
#12
Youngjun Cho, Simon J Julier, Nicolai Marquardt, Nadia Bianchi-Berthouze
The ability to monitor the respiratory rate, one of the vital signs, is extremely important for the medical treatment, healthcare and fitness sectors. In many situations, mobile methods, which allow users to undertake everyday activities, are required. However, current monitoring systems can be obtrusive, requiring users to wear respiration belts or nasal probes. Alternatively, contactless digital image sensor based remote-photoplethysmography (PPG) can be used. However, remote PPG requires an ambient source of light, and does not work properly in dark places or under varying lighting conditions...
October 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/29070755/a-case-of-optic-perineuritis-a-literature-review-of-japanese-cases-and-clinical-problems
#13
Makoto Takemaru, Keisuke Tachiyama, Yuji Shiga, Yuhei Kanaya, Yutaka Shimoe, Masaru Kuriyama
A 64-year-old woman was admitted to our hospital owing to decreased visual acuity and visual field defect. She had a similar history of decreased visual acuity and received steroid therapy 10 years ago. Brain MRI revealed gadolinium-enhancement in the sheath of the optic nerve, called "tram-track" and "doughnut" signs. Optic perineuritis (OPN) was diagnosed on the basis of her clinical manifestations, which improved on treatment with high-dose methylprednisolone (mPSL). However, clinical manifestations relapsed 10 days post-discharge; hence, she was re-admitted...
October 26, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29060734/comparison-of-motion-based-analysis-to-thermal-based-analysis-of-thermal-video-in-the-extraction-of-respiration-patterns
#14
Stephanie L Bennett, Rafik Goubran, Frank Knoefel
Non-contact methods of extracting vital signals has become a popular area of research. This is likely due to the world's aging population and the increased need for long term and remote monitoring. This paper examines and compares the potential for one modality to capture a vital sign, specifically respiration, in the presence of signal abnormalities. This paper compares temperature based-methods to motion-based methods of extracting respiration rate from thermal video of a subject performing computationally difficult respiration tests...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060235/a-simple-remote-video-based-breathing-monitor
#15
Nir Regev, Dov Wulich
Breathing monitors have become the all-important cornerstone of a wide variety of commercial and personal safety applications, ranging from elderly care to baby monitoring. Many such monitors exist in the market, some, with vital signs monitoring capabilities, but none remote. This paper presents a simple, yet efficient, real time method of extracting the subject's breathing sinus rhythm. Points of interest are detected on the subject's body, and the corresponding optical flow is estimated and tracked using the well known Lucas-Kanade algorithm on a frame by frame basis...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059984/overnight-non-contact-continuous-vital-signs-monitoring-using-an-intelligent-automatic-beam-steering-doppler-sensor-at-2-4-ghz
#16
S Batchu, H Narasimhachar, J C Mayeda, T Hall, J Lopez, T Nguyen, R E Banister, D Y C Lie
Doppler-based non-contact vital signs (NCVS) sensors can monitor heart rates, respiration rates, and motions of patients without physically touching them. We have developed a novel single-board Doppler-based phased-array antenna NCVS biosensor system that can perform robust overnight continuous NCVS monitoring with intelligent automatic subject tracking and optimal beam steering algorithms. Our NCVS sensor achieved overnight continuous vital signs monitoring with an impressive heart-rate monitoring accuracy of over 94% (i...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29053667/assay-development-for-high-content-quantification-of-sod1-mutant-protein-aggregate-formation-in-living-cells
#17
Honggun Lee, Constantin Radu, Jeung Whan Han, Regis Grailhe
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that can be caused by inherited mutations in the gene encoding copper-zinc superoxide dismutase 1 (SOD1). The structural instability of SOD1 and the detection of SOD1-positive inclusions in familial-ALS patients supports a potential causal role for misfolded and/or aggregated SOD1 in ALS pathology. In this study, we describe the development of a cell-based assay designed to quantify the dynamics of SOD1 aggregation in living cells by high content screening approaches...
October 4, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29053074/clinical-improvement-associated-with-targeted-interruption-of-the-cerebellothalamic-tract-following-mr-guided-focused-ultrasound-for-essential-tremor
#18
J Levi Chazen, Harini Sarva, Philip E Stieg, Robert J Min, Douglas J Ballon, Kane O Pryor, Paul M Riegelhaupt, Michael G Kaplitt
OBJECTIVE The objective of this study was to evaluate the utility of diffusion tensor imaging (DTI) tractography-based targeting of the dentatorubrothalamic tract (DRT) for magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy in patients with essential tremor (ET) and correlate postprocedural tract disruption with clinical outcomes. METHODS Four patients received preprocedural and immediate postprocedural DTI in addition to traditional anatomical MRI sequences for MRgFUS thalamotomy. Optimal ablation sites were selected based on the patient-specific location of the DRT as demonstrated by DTI (direct targeting) and correlated with traditional atlas-based measurements for thalamic ventral intermediate nucleus (Vim) lesioning (indirect targeting)...
October 20, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29051133/experiences-from-a-web-and-app-based-workplace-health-promotion-intervention-among-employees-in-the-social-and-health-care-sector-based-on-use-data-and-qualitative-interviews
#19
Nina Charlotte Balk-Møller, Thomas Meinert Larsen, Lotte Holm
BACKGROUND: An increasing number of Web- and app-based tools for health promotion are being developed at the moment. The ambition is generally to reach out to a larger part of the population and to help users improve their lifestyle and develop healthier habits, and thereby improve their health status. However, the positive effects are generally modest. To understand why the effects are modest, further investigation into the participants' experiences and the social aspects of using Web- and app-based health promotion tools is needed...
October 19, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29047815/electromagnetic-pulse-scattering-by-a-spacecraft-nearing-light-speed
#20
Timothy J Garner, Akhlesh Lakhtakia, James K Breakall, Craig F Bohren
Humans will launch spacecraft that travel at an appreciable fraction of the speed of light. Spacecraft traffic will be tracked by radar. Scattering of pulsed electromagnetic fields by an object in uniform translational motion at relativistic speed may be computed using the frame-hopping technique. Pulse scattering depends strongly on the velocity, shape, orientation, and composition of the object. The peak magnitude of the backscattered signal varies by many orders of magnitude, depending on whether the object is advancing toward or receding from the source of the interrogating signal...
August 1, 2017: Applied Optics
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