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https://www.readbyqxmd.com/read/29759004/is-there-a-delay-in-diagnosis-of-duchenne-muscular-dystrophy-among-preterm-born-males
#1
Aida Soim, Michael G Smith, Jennifer M Kwon, Joshua R Mann, Shiny Thomas, Emma Ciafaloni
The objective of this study was to investigate whether males who were born preterm took longer to receive a Duchenne muscular dystrophy diagnosis than term males. Data for males with Duchenne muscular dystrophy identified through a population-based surveillance system were analyzed using a Kaplan-Meier estimator. The first signs and symptoms were noted at a median age of 2 years in both groups. Median age when first signs and symptoms prompted medical evaluation was 2.59 years among preterm and 4.01 years among term males...
January 1, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29748450/concurrent-eng-and-vng-recording-in-healthy-people-preliminary-report
#2
Marzena Bielińska, Anna Polaczkiewicz, Piotr Pietkiewicz, Jarosław Miłoński, Jurek Olszewski
INTRODUCTION: The aim of the study was to evaluate concurrent recording of ENG and VNG measurements in selected diagnostic tests in healthy subjects so as to explore potential sensitivity and applicability of this kind of testing in the diagnostics of vertigo. MATERIAL AND METHODS: The study was carried out in 50 healthy subjects including 24 women and 26 men aged 20-22 (mean age of 20.5 years) reporting no otorhinolaryngological organ-related complaints and no history of any balance disorders or vertigo...
April 30, 2018: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29748160/engagement-strategies-for-self-monitoring-symptoms-of-bipolar-disorder-with-mobile-and-wearable-technology-protocol-for-a-randomized-controlled-trial
#3
Amy Cochran, Livia Belman-Wells, Melvin McInnis
BACKGROUND: Monitoring signs and symptoms in bipolar disorder (BP) is typically based on regular assessments from patient-clinician interactions. Mobile and wearable technology promises to make monitoring symptoms in BP easier, but little is known about how best to engage individuals with BP in monitoring symptoms. OBJECTIVE: The objective of this study was to provide the rationale and protocol for a randomized controlled trial that investigates engagement strategies for monitoring symptoms of BP, including the strategies of using activity trackers compared with self-reports and reviewing recorded symptoms weekly with an interviewer...
May 10, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29747450/real-time-large-scale-dense-mapping-with-surfels
#4
Xingyin Fu, Feng Zhu, Qingxiao Wu, Yunlei Sun, Rongrong Lu, Ruigang Yang
Real-time dense mapping systems have been developed since the birth of consumer RGB-D cameras. Currently, there are two commonly used models in dense mapping systems: truncated signed distance function (TSDF) and surfel. The state-of-the-art dense mapping systems usually work fine with small-sized regions. The generated dense surface may be unsatisfactory around the loop closures when the system tracking drift grows large. In addition, the efficiency of the system with surfel model slows down when the number of the model points in the map becomes large...
May 9, 2018: Sensors
https://www.readbyqxmd.com/read/29740595/dynamic-encoding-of-incentive-salience-in-the-ventral-pallidum-dependence-on-the-form-of-the-reward-cue
#5
Allison M Ahrens, Lindsay M Ferguson, Terry E Robinson, J Wayne Aldridge
Some rats are especially prone to attribute incentive salience to a cue (conditioned stimulus, CS) paired with food reward (sign-trackers, STs), but the extent they do so varies as a function of the form of the CS. Other rats respond primarily to the predictive value of a cue (goal-trackers, GTs), regardless of its form. Sign-tracking is associated with greater cue-induced activation of mesolimbic structures than goal-tracking; however, it is unclear how the form of the CS itself influences activity in neural systems involved in incentive salience attribution...
March 2018: ENeuro
https://www.readbyqxmd.com/read/29736424/value-of-double-track-sign-in-differentiating-primary-from-thrombosed-transverse-sinus-stenosis-in-patients-presumed-to-have-idiopathic-intracranial-hypertension
#6
Nasser M Aldossary
Background: Idiopathic intracranial hypertension (IIH) is primarily a disorder of young obese women of unknown etiology. The clinical presentation of IIH is similar to that of sinus thrombosis. The incidence of transverse sinus stenosis (TSS) reaches up to 90% of patients with IIH compared with normal subjects, and venous sinus thrombosis was reported in 11.4% of patients previously diagnosed as having IIH. Patients with thrombosis showed an abnormal region of double- track pattern on gadolinium (Gd) - enhanced T1WI within the dural sinus...
March 2018: ENeurologicalSci
https://www.readbyqxmd.com/read/29727277/self-gating-an-adaptive-center-of-mass-approach-for-respiratory-gating-in-pet
#7
Tao Feng, Jizhe Wang, Youjun Sun, Wentao Zhu, Yun Dong, Hongdi Li
The goal is to develop an adaptive center-of-mass (COM)-based approach for device-less respiratory gating of list-mode positron emission tomography (PET) data. Our method contains two steps. The first is to automatically extract an optimized respiratory motion signal from the list-mode data during acquisition. The respiratory motion signal was calculated by tracking the location of COM within a volume of interest (VOI). The signal prominence (SP) was calculated based on Fourier analysis of the signal. The VOI was adaptively optimized to maximize SP...
May 2018: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/29725140/environmental-drivers-of-harbour-porpoise-fine-scale-movements
#8
Floris M van Beest, Jonas Teilmann, Rune Dietz, Anders Galatius, Lonnie Mikkelsen, Dominique Stalder, Signe Sveegaard, Jacob Nabe-Nielsen
Quantifying intraspecific variation in movement behaviour of marine predators and the underlying environmental drivers is important to inform conservation management of protected species. Here, we provide the first empirical data on fine-scale movements of free-ranging harbour porpoises ( Phocoena phocoena ) in their natural habitat. Data were obtained from six individuals, tagged in two areas of the Danish North Sea, that were equipped with Global Positioning System (GPS) and dive recorder units (V-tags). We used multi-model inference and model averaging to evaluate the relative importance of various static and dynamic environmental conditions on the movement characteristics: speed, turning angle, dive duration, dive depth, dive wiggliness (a proxy for prey chasing behaviour), and post-dive duration...
2018: Marine Biology
https://www.readbyqxmd.com/read/29709718/commonly-available-activity-tracker-apps-and-wearables-as-a-mental-health-outcome-indicator-a-prospective-observational-cohort-study-among-young-adults-with-psychological-distress
#9
Alissa Knight, Niranjan Bidargaddi
BACKGROUND: Monitoring is integral to adequately recognise and track mental health indicators of symptoms and functioning. Early identification of warning signs from digital footprints could facilitate adaptive and dynamic just in-time monitoring and care for individuals with common mental disorders. METHODS: Self-report data on mental health and lifestyle behaviour from 120 male and female Australian young adults experiencing psychological distress were collected online...
April 22, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29705686/addiction-vulnerability-trait-impacts-complex-movement-control-evidence-from-sign-trackers
#10
Aaron Kucinski, Cindy Lustig, Martin Sarter
Cognitive-motivational vulnerability traits are associated with increased risk for substance addiction and relapse. Sign-tracking (ST) behavior in rats is associated with poor attentional control, mediated by an unresponsive basal forebrain cholinergic system, and an increased risk for substance addiction/relapse. A separate literature links poor attentional control and cholinergic losses to increased fall risk in Parkinson's disease. Here we tested the hypothesis that the relatively inferior attentional control of STs extends to complex movement control and a propensity for falls...
April 26, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29705094/registered-trials-report-less-beneficial-treatment-effects-than-unregistered-ones-a-meta-epidemiological-study-in-orthodontics
#11
REVIEW
Spyridon N Papageorgiou, Guilherme M Xavier, Martyn T Cobourne, Theodore Eliades
OBJECTIVES: Clinical trial registration is widely recommended, since it allows tracking of trials that helps ensure full and unbiased reporting of their results. Aim of the present overview was to provide empirical evidence on bias associated with trial registration via a meta-epidemiological approach. STUDY DESIGN AND SETTINGS: Six databases were searched in September 2017 for randomized clinical trials and systematic reviews thereof assessing the effects of orthodontic clinical interventions...
April 26, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29703852/evaluation-of-the-feasibility-and-performance-of-early-warning-scores-to-identify-patients-at-risk-of-adverse-outcomes-in-a-low-middle-income-country-setting
#12
Abi Beane, Ambepitiyawaduge Pubudu De Silva, Nirodha De Silva, Jayasingha A Sujeewa, R M Dhanapala Rathnayake, P Chathurani Sigera, Priyantha Lakmini Athapattu, Palitha G Mahipala, Aasiyah Rashan, Sithum Bandara Munasinghe, Kosala Saroj Amarasiri Jayasinghe, Arjen M Dondorp, Rashan Haniffa
OBJECTIVE: This study describes the availability of core parameters for Early Warning Scores (EWS), evaluates the ability of selected EWS to identify patients at risk of death or other adverse outcome and describes the burden of triggering that front-line staff would experience if implemented. DESIGN: Longitudinal observational cohort study. SETTING: District General Hospital Monaragala. PARTICIPANTS: All adult (age >17 years) admitted patients...
April 27, 2018: BMJ Open
https://www.readbyqxmd.com/read/29675621/myocardial-function-in-primary-antiphospholipid-syndrome-using-speckle-tracking-echocardiography
#13
Gabriela Medina, Eduardo Gómez-Bañuelos, Erick Calderón-Aranda, María Pilar Cruz-Domínguez, Olga Vera-Lastra, Luis J Jara
Antiphospholipid syndrome (APS) patients have high cardiovascular risk. Speckle-tracking echocardiography (STE) detects myocardial function. To evaluate the myocardial function in primary APS (PAPS) patients using two-dimensional echocardiography (2-D) obtaining values of left ventricle global longitudinal strain (GLS) by STE. Patients with PAPS, > 16 years, both genders, without signs and symptoms of heart disease were recruited and matched with healthy controls by age and gender. Demographic, clinical data, and cardiovascular risk factors were recorded...
April 19, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29669540/predictive-values-of-upper-gastrointestinal-cancer-alarm-symptoms-in-the-general-population-a-nationwide-cohort-study
#14
Sanne Rasmussen, Peter Fentz Haastrup, Kirubakaran Balasubramaniam, René DePont Christensen, Jens Søndergaard, Dorte Ejg Jarbøl
BACKGROUND: Survival rates for upper gastrointestinal (GI) cancer are poor since many are diagnosed at advanced stages. Fast track endoscopy has been introduced to prompt diagnosis for patients with alarm symptoms that could be indicative of upper GI cancer. However, these symptoms may represent benign conditions and little is known about the predictive values of alarm symptoms of upper GI cancer in the general population. METHODS: The study is a nationwide cohort study of 60,562 individuals aged 45 years or above randomly selected from the Danish general population...
April 18, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29643702/evaluation-of-right-ventricular-function-by-speckle-tracking-echocardiography-in-patients-with-ankylosing-spondylitis-a-case-control-study
#15
Mustafa Zungur, Ilker Gul, Senol Kobak
Background: We aimed to evaluate the right ventricular (RV) systolic function in patients with ankylosing spondylitis (AS) compared to healthy subjects by using standard echocardiography and speckle-tracking echocardiography (STE) methods. Methods: This was a case-control study in which 64 patients (mean age, 55.7 ± 9.2 years; male/female, 53/11), who had AS for at least five years (mean disease duration, 7.1 ± 2.6 years) and 70 age-matched healthy subjects (mean age, 54...
March 2018: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29626078/early-cardiac-involvement-affects-left-ventricular-longitudinal-function-in-females-carrying-%C3%AE-galactosidase-a-mutation-role-of-hybrid-positron-emission-tomography-and-magnetic-resonance-imaging-and-speckle-tracking-echocardiography
#16
Letizia Spinelli, Massimo Imbriaco, Carmela Nappi, Emanuele Nicolai, Giuseppe Giugliano, Andrea Ponsiglione, Tommaso Claudio Diomiaiuti, Eleonora Riccio, Giovanni Duro, Antonio Pisani, Bruno Trimarco, Alberto Cuocolo
BACKGROUND: Hybrid 18 F-fluorodeoxyglucose (FDG) positron emission tomography and magnetic resonance imaging may differentiate mature fibrosis or scar from fibrosis associated to active inflammation in patients with Anderson-Fabry disease, even in nonhypertrophic stage. This study was designed to compare the results of positron emission tomography and magnetic resonance cardiac imaging with those of speckle-tracking echocardiography in heterozygous Anderson-Fabry disease females. METHODS AND RESULTS: Twenty-four heterozygous females carrying α-galactosidase A mutation and without left ventricular hypertrophy underwent cardiac positron emission tomography and magnetic resonance using 18 F-FDG for glucose uptake and 2-dimensional strain echocardiography...
April 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29624621/hormonal-and-neuromuscular-responses-during-a-singles-match-in-male-professional-tennis-players
#17
Álvaro López-Samanes, Jesús G Pallarés, Alberto Pérez-López, Ricardo Mora-Rodríguez, Juan F Ortega
We sought to measure the response of cortisol concentrations around a professional tennis match and its association with hydration status and neuromuscular performance. Nine professional male tennis players were tested in a rest day, and 2-week after, during the first match of a professional tournament played in a clay-court. Salivary concentrations of cortisol (SalCC) were measured in a resting day (9:00 am and 8:00 pm), at the match day (9:00 am and 8:00 pm) and immediately before and after the match. Hydration status was assessed before the match (urine specific gravity; USG) while fluid turnover was tracked during the match...
2018: PloS One
https://www.readbyqxmd.com/read/29611861/wearable-and-flexible-electronics-for-continuous-molecular-monitoring
#18
REVIEW
Yiran Yang, Wei Gao
Wearable biosensors have received tremendous attention over the past decade owing to their great potential in predictive analytics and treatment toward personalized medicine. Flexible electronics could serve as an ideal platform for personalized wearable devices because of their unique properties such as light weight, low cost, high flexibility and great conformability. Unlike most reported flexible sensors that mainly track physical activities and vital signs, the new generation of wearable and flexible chemical sensors enables real-time, continuous and fast detection of accessible biomarkers from the human body, and allows for the collection of large-scale information about the individual's dynamic health status at the molecular level...
April 3, 2018: Chemical Society Reviews
https://www.readbyqxmd.com/read/29602178/ethanol-exposure-history-and-alcoholic-reward-differentially-alter-dopamine-release-in-the-nucleus-accumbens-to-a-reward-predictive-cue
#19
Amanda M Fiorenza, Tatiana A Shnitko, Kaitlin M Sullivan, Sudheer R Vemuru, Alexander Gomez-A, Julie Y Esaki, Charlotte A Boettiger, Claudio Da Cunha, Donita L Robinson
BACKGROUND: Conditioned stimuli (CS) that predict reward delivery acquire the ability to induce phasic dopamine release in the nucleus accumbens. This dopamine release may facilitate conditioned approach behavior, which often manifests as approach to the site of reward delivery (called 'goal-tracking') or to the CS itself (called 'sign-tracking'). Previous research has linked sign-tracking in particular to impulsivity and drug self-administration, and addictive drugs may promote the expression of sign-tracking...
March 30, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29601182/sniffing-entrapped-humans-with-sensor-arrays
#20
Andreas T Güntner, Nicolay J Pineau, Paweł Mochalski, Helmut Wiesenhofer, Agapios Agapiou, Christopher A Mayhew, Sotiris E Pratsinis
Earthquakes are lethal natural disasters frequently burying people alive under collapsed buildings. Tracking entrapped humans from their unique volatile chemical signature with hand-held devices would accelerate urban search and rescue (USaR) efforts. Here, a pilot study is presented with compact and orthogonal sensor arrays to detect the breath- and skin-emitted metabolic tracers acetone, ammonia, isoprene, CO2 , and relative humidity (RH), all together serving as sign of life. It consists of three nanostructured metal-oxide sensors (Si-doped WO3 , Si-doped MoO3 , and Ti-doped ZnO), each specifically tailored at the nanoscale for highly sensitive and selective tracer detection along with commercial CO2 and humidity sensors...
April 5, 2018: Analytical Chemistry
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