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https://www.readbyqxmd.com/read/27918279/the-sensory-features-of-a-food-cue-influence-its-ability-to-act-as-an-incentive-stimulus-and-evoke-dopamine-release-in-the-nucleus-accumbens-core
#1
Bryan F Singer, Myranda A Bryan, Pavlo Popov, Raymond Scarff, Cody Carter, Erin Wright, Brandon J Aragona, Terry E Robinson
The sensory properties of a reward-paired cue (a conditioned stimulus; CS) may impact the motivational value attributed to the cue, and in turn influence the form of the conditioned response (CR) that develops. A cue with multiple sensory qualities, such as a moving lever-CS, may activate numerous neural pathways that process auditory and visual information, resulting in CRs that vary both within and between individuals. For example, CRs include approach to the lever-CS itself (rats that "sign-track"; ST), approach to the location of reward delivery (rats that "goal-track"; GT), or an "intermediate" combination of these behaviors...
November 2016: Learning & Memory
https://www.readbyqxmd.com/read/27916165/effectiveness-and-failures-of-a-fast-track-protocol-after-cytoreduction-and-hyperthermic-intraoperative-intraperitoneal-chemotherapy-in-patients-with-peritoneal-surface-malignancies
#2
REVIEW
P A Cascales-Campos, P A Sánchez-Fuentes, J Gil, E Gil, V López-López, N Rodriguez Gomez-Hidalgo, D Fuentes, P Parrilla
BACKGROUND: The aim of this study was to analyze the results short term perioperative of patients with peritoneal surface malignancies undergoing cytoreduction with peritonectomy and HIPEC under a controlled fast track protocol and evaluate the factors related to the failure of implementation of the protocol. PATIENTS AND METHOD: We prospectively analyzed a consecutive series of patients (N = 156) with peritoneal surface malignancies treated by cytoreductive surgery with peritonectomy procedures and HIPEC from September 2008 until December 2014, in whom a fast track protocol was implemented...
December 2016: Surgical Oncology
https://www.readbyqxmd.com/read/27909098/reversible-disruption-of-neuronal-mitochondria-by-ischemic-and-traumatic-injury-revealed-by-quantitative-two-photon-imaging-in-the-neocortex-of-anesthetized-mice
#3
Mikhail Kislin, Jeremy Sword, Ioulia V Fomitcheva, Deborah Croom, Evgeny Pryazhnikov, Eero Lihavainen, Dmytro Toptunov, Heikki Rauvala, Andre S Ribeiro, Leonard Khiroug, Sergei A Kirov
: Mitochondria play a variety of functional roles in cortical neurons, from metabolic support and neuroprotection to the release of cytokines that trigger apoptosis. In dendrites, mitochondrial structure is closely linked to their function, and fragmentation (fission) of the normally elongated mitochondria indicates loss of their function under such pathological conditions as stroke and brain trauma. Using in vivo two-photon microscopy in mouse brain, we quantified mitochondrial fragmentation in a full spectrum of cortical injuries ranging from severe to mild...
December 1, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27906359/monitoring-blood-vital-bio-signs-using-secondary-speckle-patterns
#4
Talia Sirkis, Yevgeny Beiderman, Sergey Agdarov, Yafim Beiderman, Zeev Zalevsky
Continuous noninvasive measurement of vital bio-signs, such as cardiopulmonary parameters, is an important tool in the evaluation process of the patient's physiological condition and in the health monitoring of the patient. On the demand of new enabling technologies, some works have been done in continuous monitoring of blood pressure and pulse wave velocity. In this paper, we introduce further application of a novel technique for remote noncontact blood pulse wave velocity and pressure measurement based on tracking the temporal changes of reflected secondary speckle patterns produced in human skin when illuminated by a laser beam...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906358/monitoring-blood-vital-bio-signs-using-secondary-speckle-patterns
#5
Talia Sirkis, Yevgeny Beiderman, Sergey Agdarov, Yafim Beiderman, Zeev Zalevsky
Continuous noninvasive measurement of vital bio-signs, such as cardiopulmonary parameters, is an important tool in the evaluation process of the patient's physiological condition and in the health monitoring of the patient. On the demand of new enabling technologies, some works have been done in continuous monitoring of blood pressure and pulse wave velocity. In this paper, we introduce further application of a novel technique for remote noncontact blood pulse wave velocity and pressure measurement based on tracking the temporal changes of reflected secondary speckle patterns produced in human skin when illuminated by a laser beam...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27905673/single-versus-multiple-visits-for-endodontic-treatment-of-permanent-teeth
#6
REVIEW
Maddalena Manfredi, Lara Figini, Massimo Gagliani, Giovanni Lodi
BACKGROUND: Root canal treatment (RoCT), or endodontic treatment, is a common procedure in dentistry. The main indications for RoCT are irreversible pulpitis and necrosis of the dental pulp caused by carious processes, tooth cracks or chips, or dental trauma. Successful RoCT is characterised by an absence of symptoms (i.e. pain) and clinical signs (i.e. swelling and sinus tract) in teeth without radiographic evidence of periodontal involvement (i.e. normal periodontal ligament). The success of RoCT depends on a number of variables related to the preoperative condition of the tooth, as well as the endodontic procedures...
December 1, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27904790/current-concepts-in-the-treatment-of-gross-patellofemoral-instability
#7
Grant Buchanan, LeeAnne Torres, Brian Czarkowski, Charles E Giangarra
: Patellofemoral instability is a painful and commonly recurring condition, which often must be managed surgically. Diagnosis can be aided by the use of a variety of physical exam signs, such as the Q angle, Beighton hypermobility score, glide test, J sign, patellar tilt test, and apprehension test. Imaging modalities including x-ray, CT, and MRI guide both diagnosis and management by revealing trochlear dysplasia, bony malalignment, and ligamentous injury that contribute to instability...
December 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27900835/treatment-of-cutaneous-larva-migrans-with-a-single-session-of-carbon-dioxide-laser-a-study-of-ten-cases-in-the-philippines
#8
Livia Francine Soriano, Miriam Emily Piansay-Soriano
BACKGROUND: Cutaneous larva migrans (CLM) has a detrimental effect on patients' emotional and physical quality of life. Due to local unavailability of gold standard oral treatments for CLM, carbon dioxide laser was attempted. We present a case series where a single session of carbon dioxide laser treatment was associated with cessation of signs and symptoms of CLM. AIMS: The aim of this study was to assess the efficacy of a single session of carbon dioxide laser in the treatment of CLM...
November 29, 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27882168/monozygotic-twins-with-infantile-neuroaxonal-dystrophy-a-case-report-and-literature-review
#9
Haifeng Li, Yan Zou, Xinhua Bao, Hui Wang, Jiangping Wang, Huiying Jin, Yuping Che, Xiaoyan Tang
Infantile neuroaxonal dystrophy (INAD) is a rare neurodegenerative disease with early onset. PLA2G6 gene mutations have been identified in the majority individuals with INAD. In future, molecular diagnosis of INAD will replace the invasive biopsies used previously. In the present report, monozygotic male twins with INAD were referred The Children's Hospital (Zhejiang University School of Medicine, Zhejiang, China) at fifteen months old for delayed development. The older brother was found to have developmental stagnation when he was 6 months old...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27878463/tracking-of-the-inferior-alveolar-nerve-its-implication-in-surgical-planning
#10
Jimoh O Agbaje, Elke Van de Casteele, Ahmed S Salem, Dickson Anumendem, Ivo Lambrichts, Constantinus Politis
OBJECTIVES: The objective of the study is to assess the correlation between the mandibular canal tracing done on cone beam CT (CBCT) data, with the size, shape, and position of the neurovascular bundle (NB) obtained by magnetic resonance imaging (MRI). MATERIAL AND METHODS: Six human cadaver mandibles were scanned with a CBCT Promax® scanner (Planmeca, Helsinki, Finland) and with an Ingenia® 3.0 T MR system (Philips, Amsterdam, The Netherlands). The NB was segmented from the MRI dataset, while the mandibular canal (MC) tracing was done on the CBCT images...
November 22, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27852698/modifying-the-clinical-research-infrastructure-at-a-dedicated-clinical-trials-unit-assessment-of-trial-development-activation-and-participant-accrual
#11
Chad Tang, Kenneth R Hess, Dwana Sanders, Suzanne E Davis, Aman U Buzdar, Razelle Kurzrock, J Jack Lee, Funda Meric-Bernstam, David S Hong
PURPOSE: Information on processes for trials assessing investigational therapeutics is sparse. We assessed the trial development processes within the Department of Investigational Cancer Therapeutics (ICT) at MD Anderson Cancer Center and analyzed their effects on the trial activation timeline and enrollment. EXPERIMENTAL DESIGN: Data were from a prospectively maintained registry that tracks all clinical studies at MD Anderson. From this database we identified 2,261 activated phase I-III trials; 221 were done at the ICT...
November 16, 2016: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/27837333/individual-differences-in-food-cue-responsivity-are-associated-with-acute-and-repeated-cocaine-induced-vocalizations-but-not-cue-induced-vocalizations
#12
Jordan A Tripi, Micheal L Dent, Paul J Meyer
RATIONALE: Individuals prone to attribute incentive salience to food-associated stimuli ("cues") are also more sensitive to cues during drug seeking and drug taking. This may be due in part to a difference in sensitivity to the affective or other stimulus properties of the drug. In rats, these properties are associated with 50-kHz ultrasonic vocalizations (USVs), in that they are elicited during putative positive affective and motivational states, including in response to drugs of abuse...
November 11, 2016: Psychopharmacology
https://www.readbyqxmd.com/read/27830464/2d-to-3d-fusion-of-echocardiography-and-cardiac-ct-for-tavr-and-tavi-image-guidance
#13
Azira Khalil, Amir Faisal, Khin Wee Lai, Siew Cheok Ng, Yih Miin Liew
This study proposed a registration framework to fuse 2D echocardiography images of the aortic valve with preoperative cardiac CT volume. The registration facilitates the fusion of CT and echocardiography to aid the diagnosis of aortic valve diseases and provide surgical guidance during transcatheter aortic valve replacement and implantation. The image registration framework consists of two major steps: temporal synchronization and spatial registration. Temporal synchronization allows time stamping of echocardiography time series data to identify frames that are at similar cardiac phase as the CT volume...
November 9, 2016: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/27826994/diagnostic-efficacy-of-single-pass-abdominal-multidetector-row-ct-prospective-evaluation-of-a-low-dose-protocol
#14
Luigi Camera, Immacolata Liccardo, Federica Romano, Raffaele Liuzzi, Antonio Rispo, Massimo Imbriaco, Anna Testa, Gaetano Luglio, Simona De Fronzo, Fabiana Castiglione, Luigi Bucci, Arturo Brunetti
OBJECTIVES: To evaluate the diagnostic efficacy of single-pass contrast-enhanced multi-detector CT (CE-MDCT) performed with a low radiation-high contrast (LR-HC) dose protocol in selected patients with non traumatic acute bowel disease. METHODS: Sixty-five (32 M; 33 F; aged 20-67 years) consecutive patients with non traumatic acute bowel disease underwent single-pass CE-MDCT performed 70-100 sec after i.v. bolus injection of a non ionic iodinated contrast media (370 mgI/ml)...
November 9, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27822310/anaphylactic-shock-during-cement-implantation-of-a-total-hip-arthroplasty-in-a-patient-with-underlying-mastocytosis-case-report-of-a-rare-intraoperative-complication
#15
Anita Ten Hagen, Pieter Doldersum, Tom van Raaij
BACKGROUND: Cemented total hip arthroplasty (THA) is a safe and common procedure. In rare cases life threatening bone cement implantation syndrome (BCIS) may occur, which is commonly caused by pulmonary embolism (PE). CASE PRESENTATION: We describe the rare case of a 70-year old patient who underwent an elective total hip replacement. Before surgery he was diagnosed with underlying systemic indolent mastocytosis, a rare pathological disorder that may result in anaphylaxis after massive systemic mast cell activation...
2016: Patient Safety in Surgery
https://www.readbyqxmd.com/read/27819476/interoception-in-pathological-health-anxiety
#16
Susann Krautwurst, Alexander L Gerlach, Michael Witthöft
According to cognitive-behavioral models, pathological health anxiety is triggered and maintained by the perception of mostly mild and benign bodily sensations that are misinterpreted as signs of illness. Arguably, abnormalities in interoception may account for this misguided preoccupation with somatic sensations. Using a multimethod approach, the current study investigated possible abnormalities in interoception in patients with pathological health anxiety (PHA; n = 51) and healthy participants (n = 56). Different types of interoception were assessed with a heartbeat-tracking task and a signal-detection task for nonspecific skin conductance fluctuations (NSCFs task)...
November 2016: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/27815807/in-situ-sensor-advancements-for-osteoporosis-prevention-diagnosis-and-treatment
#17
REVIEW
Luting Liu, Thomas J Webster
Osteoporosis is still a serious issue in healthcare, and will continue to increase due to the aging and growth of the population. Early diagnosis is the key to successfully treating many diseases. The earlier the osteoporosis is diagnosed, the more quickly people can take action to stop bone deterioration. Motivated by this, researchers and companies have begun developing smart in situ bone sensors in order to dramatically help people to monitor their bone mass density (BMD), bone strain or bone turnover markers (BTMs); promptly track early signs of osteoporosis; and even monitor the healing process following surgery or antiresorptive therapy...
December 2016: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/27808553/representativity-and-univocity-of-traffic-signs-and-their-effect-on-trajectory-movement-in-a-driving-simulation-task-warning-signs
#18
Jose Luis Vilchez
Objective The effect of traffic signs in the motor behavior of drivers is not completely understood yet. Knowing about how humans process the meaning of signs (not just by learning but instinctively) will improve reaction time and decision making when traveling. The economic, social and psychological consequences of car accidents are well-known. Every single effort orientated to the solution of this social problem is welcome. Methods This study sounds out which traffic signs are more ergonomic for participants, from a cognitive point of view, and determines, at the same time, which is their effect in participants' movement trajectory in a driving-simulation task: the tracking task...
November 3, 2016: Traffic Injury Prevention
https://www.readbyqxmd.com/read/27799558/warm-storage-for-arc-magmas
#19
Mélanie Barboni, Patrick Boehnke, Axel K Schmitt, T Mark Harrison, Phil Shane, Anne-Sophie Bouvier, Lukas Baumgartner
Felsic magmatic systems represent the vast majority of volcanic activity that poses a threat to human life. The tempo and magnitude of these eruptions depends on the physical conditions under which magmas are retained within the crust. Recently the case has been made that volcanic reservoirs are rarely molten and only capable of eruption for durations as brief as 1,000 years following magma recharge. If the "cold storage" model is generally applicable, then geophysical detection of melt beneath volcanoes is likely a sign of imminent eruption...
October 31, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27795838/relationship-between-systemic-lupus-erythematosus-disease-activity-index-scores-and-subclinical-cardiac-problems
#20
Zahra Mirfeizi, Hoorak Poorzand, Aida Javanbakht, Mohammad Khajedaluee
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune connective-tissue disease involving multiple organs and systems. Some evidence has demonstrated that disease activity could be associated with increased risk of organ damage. OBJECTIVES: The aim of this study was to determine the association between systemic lupus erythematosus Disease Activity Index (SLEDAI) scores and subclinical cardiac involvement. METHODS: This cross-sectional study was conducted on 45 SLE patients (88% female; mean age: 31...
August 2016: Iranian Red Crescent Medical Journal
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