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https://www.readbyqxmd.com/read/28805565/noninvasive-brain-stimulation-and-implications-for-nonmotor-symptoms-in-parkinson-s-disease
#1
Irena Rektorová, Ľubomíra Anderková
Transcranial noninvasive brain stimulation includes both repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS). TMS uses a rapidly changing magnetic field to induce currents and action potentials in underlying brain tissue, whereas tDCS involves the application of weak electrical currents to modulate neuronal membrane potential. In this chapter, we provide a literature review with a focus on the therapeutic potential of both techniques in the treatment of nonmotor symptoms of Parkinson's disease (PD)...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/28780927/white-matter-microstructure-predicts-longitudinal-social-cognitive-outcomes-after-paediatric-traumatic-brain-injury-a-diffusion-tensor-imaging-study
#2
N P Ryan, S Genc, M H Beauchamp, K O Yeates, S Hearps, C Catroppa, V A Anderson, T J Silk
BACKGROUND: Deficits in social cognition may be among the most profound and disabling sequelae of paediatric traumatic brain injury (TBI); however, the neuroanatomical correlates of longitudinal outcomes in this domain remain unexplored. This study aimed to characterize social cognitive outcomes longitudinally after paediatric TBI, and to evaluate the use of sub-acute diffusion tensor imaging (DTI) to predict these outcomes. METHODS: The sample included 52 children with mild complex-severe TBI who were assessed on cognitive theory of mind (ToM), pragmatic language and affective ToM at 6- and 24-months post-injury...
August 7, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28778012/polarity-specific-transcranial-direct-current-stimulation-effects-on-object-selective-neural-responses-in-the-inferior-parietal-lobe
#3
Jorge Almeida, Ana R Martins, Fredrik Bergström, Lénia Amaral, Andreia Freixo, Ana Ganho-Ávila, Stephanie Kristensen, Dongha Lee, Joana Nogueira, Michaela Ruttorf
Neuromodulation techniques such as transcranial direct current stimulation (tDCS) are routinely used for treating neurological and neuropsychiatric disorders, and for enhancement of cognitive abilities. Recently, their effectiveness in modulating behavioral and neural responses has been questioned. Here we use excitatory and inhibitory tDCS prior to a functional magnetic resonance imaging (fMRI) experiment to show that neural responses for an area's preferred stimuli depend on the polarity of stimulation. This is an important, yet overlooked, data point in demonstrating the effectiveness of these stimulation techniques...
July 13, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28770112/anodal-transcranial-direct-current-stimulation-provokes-neuroplasticity-in-repetitive-mild-traumatic-brain-injury-in-rats
#4
Ho Jeong Kim, Soo Jeong Han
Repetitive mild traumatic brain injury (rmTBI) provokes behavioral and cognitive changes. But the study about electrophysiologic findings and managements of rmTBI is limited. In this study, we investigate the effects of anodal transcranial direct current stimulation (tDCS) on rmTBI. Thirty-one Sprague Dawley rats were divided into the following groups: sham, rmTBI, and rmTBI treated by tDCS. Animals received closed head mTBI three consecutive times a day. Anodal tDCS was applied to the left motor cortex. We evaluated the motor-evoked potential (MEP) and the somatosensory-evoked potential (SEP)...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28759803/no-evidential-value-in-samples-of-transcranial-direct-current-stimulation-tdcs-studies-of-cognition-and-working-memory-in-healthy-populations
#5
Jared Medina, Samuel Cason
A substantial number of studies have been published over the last decade, claiming that transcranial direct current stimulation (tDCS) can influence performance on cognitive tasks. However, there is some skepticism regarding the efficacy of tDCS, and evidence from meta-analyses are mixed. One major weakness of these meta-analyses is that they only examine outcomes in published studies. Given biases towards publishing positive results in the scientific literature, there may be a substantial "file-drawer" of unpublished negative results in the tDCS literature...
July 13, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28757003/transcranial-direct-current-stimulation-tdcs-modulation-of-picture-naming-and-word-reading-a-meta-analysis-of-single-session-tdcs-applied-to-healthy-participants
#6
REVIEW
Samuel J Westwood, Cristina Romani
Recent reviews quantifying the effects of single sessions of transcranial direct current stimulation (or tDCS) in healthy volunteers find only minor effects on cognition despite the popularity of this technique. Here, we wanted to quantify the effects of tDCS on language production tasks that measure word reading and picture naming. We reviewed 14 papers measuring tDCS effects across a total of 96 conditions to a) quantify effects of conventional stimulation on language regions (i.e., left hemisphere anodal tDCS administered to temporal/frontal areas) under normal conditions or under conditions of cognitive (semantic) interference; b) identify parameters which may moderate the size of the tDCS effect within conventional stimulation protocols (e...
July 27, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28747878/transcranial-electric-stimulation-can-impair-gains-during-working-memory-training-and-affects-the-resting-state-connectivity
#7
Annie Möller, Federico Nemmi, Kim Karlsson, Torkel Klingberg
Transcranial electric stimulation (tES) is a promising technique that has been shown to improve working memory (WM) performance and enhance the effect of cognitive training. However, experimental set up and electrode placement are not always determined based on neurofunctional knowledge about WM, leading to inconsistent results. Additional research on the effects of tES grounded on neurofunctional evidence is therefore necessary. Sixty young, healthy, volunteers, assigned to six different groups, participated in 5 days of stimulation or sham treatment...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28709999/tdcs-over-the-right-inferior-frontal-gyrus-disrupts-control-of-interference-in-memory-a-retrieval-induced-forgetting-study
#8
Davide F Stramaccia, Barbara Penolazzi, Gianmarco Altoè, Giovanni Galfano
Retrieving information from episodic memory may result in later inaccessibility of related but task-irrelevant information. This phenomenon, known as retrieval-induced forgetting, is thought to represent a specific instance of broader cognitive control mechanisms, that would come into play during memory retrieval, whenever non-target competing memories interfere with recall of target items. Recent neuroimaging studies have shown an association between these mechanisms and the activity of the right Prefrontal Cortex...
July 11, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28707568/effects-of-transcranial-direct-current-stimulation-on-neural-network-structure-in-young-and-older-adults
#9
Andrew Martin, Marcus Meinzer, Robert Lindenberg, Mira M Sieg, Laura Nachtigall, Agnes Flöel
Transcranial direct current stimulation (tDCS) may be a viable tool to improve motor and cognitive function in advanced age. However, although a number of studies have demonstrated improved cognitive performance in older adults, other studies have failed to show restorative effects. The neural effects of beneficial stimulation response in both age groups is lacking. In the current study, tDCS was administered during simultaneous fMRI in 42 healthy young and older participants. Semantic word generation and motor speech baseline tasks were used to investigate behavioral and neural effects of uni- and bihemispheric motor cortex tDCS in a three-way, crossover, sham tDCS controlled design...
July 14, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/28701986/controlling-the-anchoring-effect-through-transcranial-direct-current-stimulation-tdcs-to-the-right-dorsolateral-prefrontal-cortex
#10
Jianbiao Li, Xile Yin, Dahui Li, Xiaoli Liu, Guangrong Wang, Liang Qu
Selective accessibility mechanisms indicate that anchoring effects are results of selective retrieval of working memory. Neuroimaging studies have revealed that the right dorsolateral prefrontal cortex (DLPFC) is closely related to memory retrieval and performance. However, no research has investigated the effect of changing the cortical excitability in right DLPFC on anchoring effects. Transcranial direct current stimulation (tDCS) can modulate the excitability of the human cerebral cortex, while anodal and cathodal tDCS are postulated to increase or decrease cortical activity, respectively...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28688701/basic-and-functional-effects-of-transcranial-electrical-stimulation-tes-an-introduction
#11
REVIEW
Fatemeh Yavari, Asif Jamil, Mohsen Mosayebi Samani, Liliane Pinto Vidor, Michael A Nitsche
Non-invasive brain stimulation (NIBS) has been gaining increased popularity in human neuroscience research during the last years. Among the emerging NIBS tools is transcranial electrical stimulation (tES), whose main modalities are transcranial direct, and alternating current stimulation (tDCS, tACS). In tES, a small current (usually less than 3mA) is delivered through the scalp. Depending on its shape, density, and duration, the applied current induces acute or long-lasting effects on excitability and activity of cerebral regions, and brain networks...
July 5, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28681715/motor-cortex-trns-improves-pain-affective-and-cognitive-impairment-in-patients-with-fibromyalgia-preliminary-results-of-a-randomised-sham-controlled-trial
#12
Massimiliano Curatolo, Giuseppe La Bianca, Giuseppe Cosentino, Roberta Baschi, Giuseppe Salemi, Rossella Talotta, Marcello Romano, Giovanni Triolo, Marina De Tommaso, Brigida Fierro, Filippo Brighina
OBJECTIVES: Fibromyalgia (FM) is a clinical syndrome characterised by widespread musculoskeletal pain, chronic fatigue, cognitive deficits, and sleep and mood disorders. The effectiveness of most pharmacological treatments is limited, and there is a need for new, effective and well-tolerated therapies. It has recently been shown that transcranial direct-current stimulation (tDCS) of the motor cortex reduces pain, and that tDCS of the dorso-lateral prefrontal cortex (DLPFC) improves anxiety, depression and cognitive impairment in FM patients...
May 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28675465/brain-volumetric-correlates-of-inhibition-and-cognitive-flexibility-16-years-following-childhood-traumatic-brain-injury
#13
Kelleynne Yu, Marc L Seal, Jonathan Reyes, Celia Godfrey, Vicki Anderson, Chris Adamson, Nicholas P Ryan, Stephen J C Hearps, Cathy Catroppa
Executive functions (EFs), such as inhibition and cognitive flexibility, are essential for everyday functioning, including regulation of socially appropriate emotional responses. These skills develop during childhood and continue maturing into early adulthood. The current study aimed to investigate the very long-term impact of childhood traumatic brain injury (TBI) on inhibition and cognitive flexibility, and to examine whether global white matter is associated with these abilities. Twenty-eight young adult survivors of childhood TBI (mean age at 16-year follow-up = 21...
July 4, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/28637840/promoting-sleep-oscillations-and-their-functional-coupling-by-transcranial-stimulation-enhances-memory-consolidation-in-mild-cognitive-impairment
#14
Julia Ladenbauer, Josef Ladenbauer, Nadine Külzow, Rebecca de Boor, Elena Avramova, Ulrike Grittner, Agnes Flöel
Alzheimer's disease (AD) not only involves loss of memory functions, but also prominent deterioration of sleep physiology, which is already evident at the stage of mild cognitive impairment (MCI). Cortical slow oscillations (SO; 0.5-1 Hz) and thalamocortical spindle activity (12-15 Hz) during sleep, and their temporal coordination, are considered critical for memory formation. We investigated the potential of slow oscillatory transcranial direct current stimulation (so-tDCS), applied during a daytime nap in a sleep-state-dependent manner, to modulate these activity patterns and sleep-related memory consolidation in nine male and seven female human patients with MCI...
July 26, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28588441/tempering-proactive-cognitive-control-by-transcranial-direct-current-stimulation-of-the-right-but-not-the-left-lateral-prefrontal-cortex
#15
Carlos J Gómez-Ariza, María C Martín, Julia Morales
Behavioral and neuroimaging data support the distinction of two different modes of cognitive control: proactive, which involves the active and sustained maintenance of task-relevant information to bias behavior in accordance with internal goals; and reactive, which entails the detection and resolution of interference at the time it occurs. Both control modes may be flexibly deployed depending on a variety of conditions (i.e., age, brain alterations, motivational factors, prior experience). Critically, and in line with specific predictions derived from the dual mechanisms of control account (Braver, 2012), findings from neuroimaging studies indicate that the same lateral prefrontal regions (i...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28583011/cognitive-training-and-noninvasive-brain-stimulation-for-cognition-in-parkinson-s-disease-a-meta-analysis
#16
Blake J Lawrence, Natalie Gasson, Romola S Bucks, Lakkhina Troeung, Andrea M Loftus
BACKGROUND: Many people with Parkinson's disease (PD) experience cognitive decline. It is not known whether cognitive training or noninvasive brain stimulation are effective at alleviating cognitive deficits in PD. OBJECTIVE: To examine cognitive training and non-invasive brain stimulation interventions for cognition in PD. METHODS: An extensive search was conducted of published and unpublished studies in online databases. Studies were selected if they were controlled trials examining standard (not individualized) or tailored (individualized) cognitive training, repetitive transcranial magnetic stimulation (rTMS), or transcranial direct current stimulation (tDCS) in PD, with outcomes measured by standardized neuropsychological tests...
July 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28572072/the-critical-role-of-cognitive-based-trait-differences-in-transcranial-direct-current-stimulation-tdcs-suppression-of-food-craving-and-eating-in-frank-obesity
#17
Mary Katherine Ray, Maria D Sylvester, Lauren Osborn, Joel Helms, Bulent Turan, Emilee E Burgess, Mary M Boggiano
Obesity remains a major public health concern and novel treatments are needed. Transcranial direct current stimulation (tDCS) is a neuromodulation technique shown to reduce food craving and consumption, especially when targeting the dorsolateral prefrontal cortex (DLPFC) with a right anode/left cathode electrode montage. Despite the implications to treat frank (non-bingeeating) obesity, no study has tested the right anode/left cathode montage in this population. Additionally, most tDCS appetite studies have not controlled for differences in traits under DLPFC control that may influence how well one responds to tDCS...
September 1, 2017: Appetite
https://www.readbyqxmd.com/read/28566193/efficacy-of-transcranial-direct-current-stimulation-over-primary-motor-cortex-anode-and-contralateral-supraorbital-area-cathode-on-clinical-pain-severity-and-mobility-performance-in-persons-with-knee-osteoarthritis-an-experimenter-and-participant-blinded-randomized
#18
Hyochol Ahn, Adam J Woods, Mark E Kunik, Abhishek Bhattacharjee, Zhiguo Chen, Eunyoung Choi, Roger B Fillingim
BACKGROUND: Previous studies indicate that transcranial direct current stimulation (tDCS) with anode over motor cortex (M1) and cathode over contralateral supraorbital region (SO) may be effective in reducing pain, but these studies are limited in number and have not focused on older adults with osteoarthritis (OA). OBJECTIVE: To evaluate the preliminary efficacy and safety of M1-SO applied tDCS on clinical pain severity and mobility performance in adults with knee OA pain...
May 19, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28559804/using-transcranial-direct-current-stimulation-to-enhance-creative-cognition-interactions-between-task-polarity-and-stimulation-site
#19
REVIEW
Adam B Weinberger, Adam E Green, Evangelia G Chrysikou
Creative cognition is frequently described as involving two primary processes, idea generation and idea selection. A growing body of research has used transcranial direct current stimulation (tDCS) to examine the neural mechanisms implicated in each of these processes. This literature has yielded a diverse set of findings that vary depending on the location and type (anodal, cathodal, or both) of electrical stimulation employed, as well as the task's reliance on idea generation or idea selection. As a result, understanding the interactions between stimulation site, polarity and task demands is required to evaluate the potential of tDCS to enhance creative performance...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28555104/tdcs-over-the-motor-cortex-shows-differential-effects-on-action-and-object-words-in-associative-word-learning-in-healthy-aging
#20
Meret Branscheidt, Julia Hoppe, Nils Freundlieb, Pienie Zwitserlood, Gianpiero Liuzzi
Healthy aging is accompanied by a continuous decline in cognitive functions. For example, the ability to learn languages decreases with age, while the neurobiological underpinnings for the decline in learning abilities are not known exactly. Transcranial direct current stimulation (tDCS), in combination with appropriate experimental paradigms, is a well-established technique to investigate the mechanisms of learning. Based on previous results in young adults, we tested the suitability of an associative learning paradigm for the acquisition of action- and object-related words in a cohort of older participants...
2017: Frontiers in Aging Neuroscience
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