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https://www.readbyqxmd.com/read/29351713/-living-with-localized-prostate-cancer-decision-making-and-coping-with-the-illness
#1
Friederike Kendel, Isabella Otto, Jennifer Engler, Mark Schrader, Christine Holmberg
BACKGROUND: Men diagnosed with localized prostate cancer must make a choice between treatment strategies that differ considerably in their side effects and have different long-term requirements for coping with the disease. The aim of this study was to describe how men perceive their treatment decision retrospectively and which coping strategies they use. MATERIAL & METHODS: Fifteen men (age mean=67.13±9.38 years) diagnosed with localized prostate cancer participated in three focus groups, grouped according to the treatment strategies radical prostatectomy, radiotherapy, and active surveillance...
January 19, 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29351507/-i-smoke-like-this-to-suppress-these-issues-that-are-flaws-of-my-character-challenges-and-facilitators-of-cessation-among-smokers-with-bipolar-disorder
#2
Jaimee L Heffner, Noreen L Watson, Jennifer B McClure, Robert M Anthenelli, Sarah Hohl, Jonathan B Bricker
OBJECTIVE: Smokers with bipolar disorder (BD) have low rates of successful quitting, yet no prior studies have evaluated the process of quitting among these smokers in the context of a current quit attempt. To facilitate development of more effective interventions, we conducted a qualitative exploration of challenges and facilitators of quitting in an intervention study for smokers with BD. METHODS: Participants were adult daily smokers with BD (n = 10) who completed a 10-week smoking cessation intervention consisting of Acceptance and Commitment Therapy (ACT) and nicotine patch...
January 19, 2018: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/29351363/carers-experiences-of-home-enteral-feeding-a-survey-exploring-medicines-administration-challenges-and-strategies
#3
D Alsaeed, D Furniss, A Blandford, F Smith, M Orlu
WHAT IS KNOWN AND OBJECTIVES: The use of enteral tube feeding at home is becoming more widespread, with patients ranging in age and diseases. Dysphagia and swallowing difficulties can compromise nutritional intake and the administration of oral medications, affecting therapeutic outcomes negatively. Carers' experiences of medicines administration and medicines optimization have not been explored fully. The objectives of this study were to identify issues carers experience in medicines administration; the strategies they have developed to cope; and suggestions to improve the medicines administration process...
January 19, 2018: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29351338/stockouts-of-hiv-commodities-in-public-health-facilities-in-kinshasa-barriers-to-end-hiv
#4
Tinne Gils, Claire Bossard, Kristien Verdonck, Philip Owiti, Ilse Casteels, Maria Mashako, Gilles Van Cutsem, Tom Ellman
Stockouts of HIV commodities increase the risk of treatment interruption, antiretroviral resistance, treatment failure, morbidity and mortality. The study objective was to assess the magnitude and duration of stockouts of HIV medicines and diagnostic tests in public facilities in Kinshasa, Democratic Republic of the Congo. This was a cross-sectional survey involving visits to facilities and warehouses in April and May 2015. All zonal warehouses, all public facilities with more than 200 patients on antiretroviral treatment (ART) (high-burden facilities) and a purposive sample of facilities with 200 or fewer patients (low-burden facilities) in Kinshasa were selected...
2018: PloS One
https://www.readbyqxmd.com/read/29351192/seed-endophyte-microbiome-of-crotalaria-pumila-unpeeled-identification-of-plant-beneficial-methylobacteria
#5
Ariadna S Sánchez-López, Isabel Pintelon, Vincent Stevens, Valeria Imperato, Jean-Pierre Timmermans, Carmen González-Chávez, Rogelio Carrillo-González, Jonathan Van Hamme, Jaco Vangronsveld, Sofie Thijs
Metal contaminated soils are increasing worldwide. Metal-tolerant plants growing on metalliferous soils are fascinating genetic and microbial resources. Seeds can vertically transmit endophytic microorganisms that can assist next generations to cope with environmental stresses, through yet poorly understood mechanisms. The aims of this study were to identify the core seed endophyte microbiome of the pioneer metallophyte Crotalaria pumila throughout three generations, and to better understand the plant colonisation of the seed endophyte Methylobacterium sp...
January 19, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29351009/life-history-traits-evolved-jointly-with-climatic-niche-and-disturbance-regime-in-the-genus-leucadendron-proteaceae
#6
Jeanne Tonnabel, Frank M Schurr, Florian Boucher, Wilfried Thuiller, Julien Renaud, Emmanuel J P Douzery, Ophélie Ronce
Organisms have evolved a diversity of life-history strategies to cope with variation in their environment. Persistence as adults and/or seeds across recruitment events allows species to dampen the effects of environmental fluctuations. The evolution of life cycles with overlapping generations should thus permit the colonization of environments with uncertain recruitment. We tested this hypothesis in Leucadendron (Proteaceae), a genus with high functional diversity native to fire-prone habitats in the South African fynbos...
February 2018: American Naturalist
https://www.readbyqxmd.com/read/29350875/highly-dynamic-wintering-strategies-in-migratory-geese-coping-with-environmental-change
#7
Kevin Kuhlmann Clausen, Jesper Madsen, Fred Cottaar, Eckhart Kuijken, Christine Verscheure
When and where to move is a fundamental decision to migratory birds, and the fitness-related costs and benefits of migratory choices make them subject to strong selective forces. Site use and migration routes are outcomes of opportunities in the surrounding landscape, and the optimal migration strategy may be conservative or explorative depending on the variability of the environment occupied by the species. This study applies 25 years of resighting data to examine development in winter migration strategy of pink-footed geese divided among Denmark, the Netherlands and Belgium, and analyse potential drivers of strategy change as well as individuals' likelihood to break with migratory tradition...
January 19, 2018: Global Change Biology
https://www.readbyqxmd.com/read/29350704/caregiver-caf%C3%A3-providing-education-and-support-to-family-caregivers-of-patients-with-cancer%C3%A2
#8
Joanne P Finley
BACKGROUND: The many burdens faced by caregivers of patients with cancer are well documented. Caregivers are asked to perform procedures, make assessments, coordinate care, and communicate with healthcare providers at an increasingly complex level. A caregiver quality improvement project, in the form of a Caregiver Café, was instituted at a National Cancer Institute-designated comprehensive cancer center.
. OBJECTIVES: The objectives of the café are to (a) provide respite and a place for caregivers to relax and be nurtured, (b) provide a place for caregivers to meet and support each other, (c) provide answers to caregiver questions, and (d) recommend appropriate caregiver resources...
February 1, 2018: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29350690/fluidics-and-rheology-in-phaco-surgery-what-matters-and-what-is-the-hype
#9
L Benjamin
Rheology can be defined as the study of materials flow behaviour under applied deformation forces (stresses). Inside the eye during cataract surgery, transient or reversible deformation (elasticity) and permanent or irreversible deformation (flow) can both apply. Although the fluidics of modern phaco machines is an important part of this talk, there are a number of issues relating to flow and fluids in the eye during cataract surgery, which are unrelated to the machine, which can hinder or help the operating surgeon in removing a cataract...
January 19, 2018: Eye
https://www.readbyqxmd.com/read/29350481/emotion-regulation-and-positive-affect-in-the-context-of-salivary-alpha-amylase-response-to-pain-in-children-with-cancer
#10
Brooke N Jenkins, Douglas A Granger, Ryan J Roemer, Ariana Martinez, Tara K Torres, Michelle A Fortier
BACKGROUND: Children with cancer routinely undergo painful medical procedures invoking strong physiological stress responses. Resilience to this pain may be conferred through resources such as emotion regulation strategies and positive affect. PROCEDURE: This study measured dispositional positive affect in children with cancer (N = 73) and randomly assigned participants to one of three emotion regulation strategy conditions (distraction, reappraisal, or reassurance)...
January 19, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29349910/accuracy-of-a-new-elastomeric-impression-material-for-complete-arch-dental-implant-impressions
#11
Mirza R Baig, Muaiyed M Buzayan, Norsiah Yunus
AIM: The aim of the present study was to assess the accuracy of multi-unit dental implant casts obtained from two elastomeric impression materials, vinyl polyether silicone (VPES) and polyether (PE), and to test the effect of splinting of impression copings on the accuracy of implant casts. METHODS: Forty direct impressions of a mandibular reference model fitted with six dental implants and multibase abutments were made using VPES and PE, and implant casts were poured (N = 20)...
January 18, 2018: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/29349791/predicting-patterns-of-change-and-stability-in-student-performance-across-a-medical-degree
#12
Barbara Griffin, Piers Bayl-Smith, Wendy Hu
CONTEXT: Evidence of predictive validity is essential for making robust selection decisions in high-stakes contexts such as medical student selection. Currently available evidence is limited to the prediction of academic performance at single points in time with little understanding of the factors that might undermine the predictive validity of tests of academic and non-academic qualities considered important for success. This study addressed these issues by predicting students' changing performance across a medical degree and assessing whether factors outside an institution's control (such as the uptake of commercial coaching) impact validity...
January 19, 2018: Medical Education
https://www.readbyqxmd.com/read/29349564/retraction-note-to-factors-associated-with-post-stroke-depression-and-fatigue-lesion-location-and-coping-styles
#13
Changjuan Wei, Fang Zhang, Li Chen, Xiaofeng Ma, Nan Zhang, Junwei Hao
The Editors-in-Chief are retracting the original article because it shows significant overlap with an article previously published by the authors [1]. All authors agree to this retraction.
January 18, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29348641/refined-control-of-cell-stemness-allowed-animal-evolution-in-the-oxic-realm
#14
REVIEW
Emma U Hammarlund, Kristoffer von Stedingk, Sven Påhlman
Animal diversification on Earth has long been presumed to be associated with the increasing extent of oxic niches. Here, we challenge that view. We start with the fact that hypoxia (<1-3% O2) maintains cellular immaturity (stemness), whereas adult stem cells continuously-and paradoxically-regenerate animal tissue in oxygenated settings. Novel insights from tumour biology illuminate how cell stemness nevertheless can be achieved through the action of oxygen-sensing transcription factors in oxygenated, regenerating tissue...
January 18, 2018: Nature Ecology & Evolution
https://www.readbyqxmd.com/read/29348581/identifying-metabolic-pathways-for-production-of-extracellular-polymeric-substances-by-the-diatom-fragilariopsis-cylindrus-inhabiting-sea-ice
#15
Shazia N Aslam, Jan Strauss, David N Thomas, Thomas Mock, Graham J C Underwood
Diatoms are significant primary producers in sea ice, an ephemeral habitat with steep vertical gradients of temperature and salinity characterizing the ice matrix environment. To cope with the variable and challenging conditions, sea ice diatoms produce polysaccharide-rich extracellular polymeric substances (EPS) that play important roles in adhesion, cell protection, ligand binding and as organic carbon sources. Significant differences in EPS concentrations and chemical composition corresponding to temperature and salinity gradients were present in sea ice from the Weddell Sea and Eastern Antarctic regions of the Southern Ocean...
January 18, 2018: ISME Journal
https://www.readbyqxmd.com/read/29347920/a-qualitative-study-of-tobacco-interventions-for-lgbtq-youth-and-young-adults-overarching-themes-and-key-learnings
#16
N Bruce Baskerville, Katy Wong, Alanna Shuh, Aneta Abramowicz, Darly Dash, Aamer Esmail, Ryan Kennedy
BACKGROUND: Smoking prevalence is very high among lesbian, gay, bisexual, transgendered and queer (LGBTQ+) youth and young adults (YYA) compared to non-LGBTQ+ YYA. A knowledge gap exists on culturally appropriate and effective prevention and cessation efforts for members of this diverse community, as limited interventions have been developed with and for this population, and there are very few studies determining the impact of these interventions. This study identifies the most salient elements of LGBTQ+ cessation and prevention interventions from the perspective of LGBTQ+ YYA...
January 18, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29347912/genome-wide-analysis-of-the-potato-hsp20-gene-family-identification-genomic-organization-and-expression-profiles-in-response-to-heat-stress
#17
Peng Zhao, Dongdong Wang, Ruoqiu Wang, Nana Kong, Chao Zhang, Chenghui Yang, Wentao Wu, Haoli Ma, Qin Chen
BACKGROUND: Heat shock proteins (Hsps) are essential components in plant tolerance mechanism under various abiotic stresses. Hsp20 is the major family of heat shock proteins, but little of Hsp20 family is known in potato (Solanum tuberosum), which is an important vegetable crop that is thermosensitive. RESULTS: To reveal the mechanisms of potato Hsp20s coping with abiotic stresses, analyses of the potato Hsp20 gene family were conducted using bioinformatics-based methods...
January 18, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29347828/change-in-hiv-related-stigma-in-south-africa-between-2004-and-2016-a-cross-sectional-community-study
#18
Maretha J Visser
A critical component of an AIDS-free generation is to reduce HIV-related stigma. Previous research predicted that stigma would decline over time with increased contact with PLWH, understanding of the disease and availability of treatment. The aim of the research was to explore change in stigma over a 12-year period, by comparing data collected from two large cross-sectional samples from South African communities in 2004 (before the roll-out of antiretroviral treatment (ART)) and in 2016. Students recruited respondents according to criteria related to age, gender, race and area of living...
January 18, 2018: AIDS Care
https://www.readbyqxmd.com/read/29346942/transitions-in-optimal-adaptive-strategies-for-populations-in-fluctuating-environments
#19
Andreas Mayer, Thierry Mora, Olivier Rivoire, Aleksandra M Walczak
Biological populations are subject to fluctuating environmental conditions. Different adaptive strategies can allow them to cope with these fluctuations: specialization to one particular environmental condition, adoption of a generalist phenotype that compromises between conditions, or population-wise diversification (bet hedging). Which strategy provides the largest selective advantage in the long run depends on the range of accessible phenotypes and the statistics of the environmental fluctuations. Here, we analyze this problem in a simple mathematical model of population growth...
September 2017: Physical Review. E
https://www.readbyqxmd.com/read/29346757/p53-suppresses-metabolic-stress-induced-ferroptosis-in-cancer-cells
#20
Amy Tarangelo, Leslie Magtanong, Kathryn T Bieging-Rolett, Yang Li, Jiangbin Ye, Laura D Attardi, Scott J Dixon
How cancer cells respond to nutrient deprivation remains poorly understood. In certain cancer cells, deprivation of cystine induces a non-apoptotic, iron-dependent form of cell death termed ferroptosis. Recent evidence suggests that ferroptosis sensitivity may be modulated by the stress-responsive transcription factor and canonical tumor suppressor protein p53. Using CRISPR/Cas9 genome editing, small-molecule probes, and high-resolution, time-lapse imaging, we find that stabilization of wild-type p53 delays the onset of ferroptosis in response to cystine deprivation...
January 16, 2018: Cell Reports
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