keyword
https://read.qxmd.com/read/38174013/pharyngeal-oxygen-delivery-device-sustains-manikin-lung-oxygenation-longer-than-high-flow-nasal-cannula
#21
JOURNAL ARTICLE
Jeramie B Hanson, John R Williams, Emily H Garmon, Phillip M Morris, Russell K McAllister, Courtney N Shaver, William C Culp
PURPOSE: Hypoxemia during a failed airway scenario is life threatening. A dual-lumen pharyngeal oxygen delivery device (PODD) was developed to fit inside a traditional oropharyngeal airway for undisrupted supraglottic oxygenation and gas analysis during laryngoscopy and intubation. We hypothesized that the PODD would provide oxygen as effectively as high-flow nasal cannula (HFNC) while using lower oxygen flow rates. METHODS: We compared oxygen delivery of the PODD to HFNC in a preoxygenated, apneic manikin lung that approximated an adult functional residual capacity...
2024: Proceedings of the Baylor University Medical Center
https://read.qxmd.com/read/38168317/image-based-spatial-transcriptomics-identifies-molecular-niche-dysregulation-associated-with-distal-lung-remodeling-in-pulmonary-fibrosis
#22
Annika Vannan, Ruqian Lyu, Arianna L Williams, Nicholas M Negretti, Evan D Mee, Joseph Hirsh, Samuel Hirsh, David S Nichols, Carla L Calvi, Chase J Taylor, Vasiliy V Polosukhin, Ana Pm Serezani, A Scott McCall, Jason J Gokey, Heejung Shim, Lorraine B Ware, Matthew J Bacchetta, Ciara M Shaver, Timothy S Blackwell, Rajat Walia, Jennifer Ms Sucre, Jonathan A Kropski, Davis J McCarthy, Nicholas E Banovich
The human lung is structurally complex, with a diversity of specialized epithelial, stromal and immune cells playing specific functional roles in anatomically distinct locations, and large-scale changes in the structure and cellular makeup of this distal lung is a hallmark of pulmonary fibrosis (PF) and other progressive chronic lung diseases. Single-cell transcriptomic studies have revealed numerous disease-emergent/enriched cell types/states in PF lungs, but the spatial contexts wherein these cells contribute to disease pathogenesis has remained uncertain...
December 17, 2023: bioRxiv
https://read.qxmd.com/read/38163682/non-destructive-egg-breed-separation-using-advanced-voc-analytical-techniques-hsse-gc-ms-ptr-tof-ms-and-sift-ms-assessment-of-performance-and-systems-complementarity
#23
JOURNAL ARTICLE
Matthias Corion, Miguel Portillo-Estrada, Simão Santos, Jeroen Lammertyn, Bart De Ketelaere, Maarten Hertog
Over the past decade, advanced analytical techniques have been utilized to examine volatile organic compounds (VOCs) in eggs. These VOCs offer valuable insights into factors such as freshness, fertility, the presence of cracks, embryo sex, and breed. In our study, we assessed three mass spectrometry-based systems (headspace sorptive extraction gas chromatography-mass spectrometry; HSSE-GC-MS, proton transfer reaction time-of-flight-mass spectrometry; PTR-TOF-MS; and selected ion flow tube mass spectrometry; SIFT-MS) to analyze and identify VOCs present in intact hatching eggs from three distinct breeds (Dekalb white layer, Shaver brown layer, and Ross 308 broiler)...
January 2024: Food Research International
https://read.qxmd.com/read/38157949/histo-morphological-effects-on-equine-synovium-after-arthroscopic-synovectomy-using-two-different-motorized-synovial-resectors-and-two-different-intensities
#24
JOURNAL ARTICLE
A Troillet, J Hildebrand, M H Stoffel, S Schwabe, K Winter, W Brehm
The purpose of the study was to determine the histo-morphological effects on villous synovium after synovectomy using two different motorized synovial resectors and two different intensities ex-vivo. Thirty-three (n=33) equine metacarpophalangeal/metatarsophalangeal joints were used. Synovectomy was performed along the dorsomedial/dorsolateral synovium (n=66) using two motorized synovial resectors (aggressive full radius resector, AFRR, used at two intensities: single treatment, n= 24 vs. triple treatment, n= 21 vs...
December 27, 2023: Journal of Equine Veterinary Science
https://read.qxmd.com/read/38150787/sediment-carbon-storage-differs-in-native-and-non-native-caribbean-seagrass-beds
#25
JOURNAL ARTICLE
Catherine L Brenner, Stephanie R Valdez, Y Stacy Zhang, Elizabeth C Shaver, Brent B Hughes, Brian R Silliman, Joseph P Morton
Non-native species are expanding globally and can alter ecosystem functions, including food web dynamics, community structure and carbon storage. Seagrass are foundation species that contribute a variety of ecosystem services in near-shore coastal ecosystems, including a significant sink of carbon. In the Caribbean, the rapidly expanding non-native Halophila stipulacea has unknown impacts on carbon storage. To investigate the impacts on carbon storage, we quantified organic carbon (Corg ) content in sediment and seagrass tissues from monotypic H...
December 18, 2023: Marine Environmental Research
https://read.qxmd.com/read/38147017/voluntary-attrition-among-traditional-baccalaureate-nursing-students-an-integrative-review
#26
JOURNAL ARTICLE
Danielle E Shaver, Jennifer D Viveiros
AIM: The purpose of this review is to synthesize what is known about voluntary attrition from baccalaureate nursing education. BACKGROUND: Understanding the reasons behind elective, voluntary attrition from nursing programs can help maximize resources and graduate more nurses into the workforce. METHOD: An integrative review of the literature was conducted using the search strategy outlined by Whittemore and Knafl. The validated Mixed-Methods Appraisal Tool was used to assess the quality of the studies found in the search...
December 27, 2023: Nursing Education Perspectives
https://read.qxmd.com/read/38126336/genitourinary-syndrome-of-menopause-prevalence-and-predictors
#27
REVIEW
Nancy F Woods, Joan F Shaver, Judith A Berg
The genitourinary syndrome of menopause (GSM) has been proposed as a diagnosis by a consensus of clinicians and investigators. Our purpose for this paper is to review extant evidence about: 1) the breadth of symptoms and symptom clusters as related to the syndrome; 2) the prevalence of GSM (includes vulvar and vaginal atrophy); 3) factors that are associated with, predict, or explain the syndrome; and 4) what should be pursued for expanding meaningful evidence. Within recent literature, we found a wide range of prevalence estimates, likely a function of the differing populations studied, study design, and methods of data collection...
March 1, 2024: Clinical Obstetrics and Gynecology
https://read.qxmd.com/read/38110361/analytical-validation-of-aptamer-based-serum-vancomycin-monitoring-relative-to-automated-immunoassays
#28
JOURNAL ARTICLE
Yu Liu, John O Mack, Maryam Shojaee, Alexander Shaver, Ankitha George, William Clarke, Neel Patel, Netzahualcóyotl Arroyo-Currás
The practice of monitoring therapeutic drug concentrations in patient biofluids can significantly improve clinical outcomes while simultaneously minimizing adverse side effects. A model example of this practice is vancomycin dosing in intensive care units. If dosed correctly, vancomycin can effectively treat methicillin-resistant streptococcus aureus (MRSA) infections. However, it can also induce nephrotoxicity or fail to kill the bacteria if dosed too high or too low, respectively. Although undeniably important to achieve effectiveness, therapeutic drug monitoring remains inconvenient in practice due primarily to the lengthy process of sample collection, transport to a centralized facility, and analysis using costly instrumentation...
December 18, 2023: ACS Sensors
https://read.qxmd.com/read/38095911/oncologic-safety-of-close-margins-in-patients-with-low-to-intermediate-grade-major-salivary-gland-carcinoma
#29
JOURNAL ARTICLE
Mirabelle Sajisevi, Kenny Nguyen, Peter Callas, Andrew J Holcomb, Emre Vural, Kyle P Davis, Carissa M Thomas, Karolina A Plonowska-Hirschfeld, John S Stein, Antoine Eskander, Kiran Kakarala, Danny J Enepekides, Michael P Hier, William R Ryan, Ameya A Asarkar, Ricardo Aulet, Rebecca K Bell, Michael A Blasco, Vanessa B Bowmaster, Clayton P Burruss, Jeffson Chung, Kimberly Chan, Brent A Chang, Charles S Coffey, David M Cognetti, Dylan J Cooper, Joehassin Cordero, John Donovan, Yue Jennifer Du, Yusuf Dundar, Rogerio A Dedivitis, Heather A Edwards, Boban M Erovic, Philip A Feinberg, Emily A Garvey, David P Goldstein, Joseph F Goodman, Rafael N Goulart, Neerav Goyal, Stefan Grasl, Jonathan P Giurintano, Nikita Gupta, Andy M Habib, Trevor G Hackman, Jared H Hara, Christina Henson, Michael L Hinni, Nadia Hua, Stephanie Johnson-Obaseki, Aditya Juloori, Noah S Kalman, Alexandra E Kejner, Sobia F Khaja, Jamie A Ku, Arnaud Lambert, Bao K Luu, Kelly R Magliocca, Luiz R Medina Dos Santos, Cara Michael, Brett A Miles, Giulianno Molina de Melo, Michael G Moore, Gregoire B Morand, Kauê Moura, Laith Mukdad, Hesameddin Noroozi, Rusha Patel, Joseph A Paydarfar, Nader Sadeghi, Fabrice N Savaria, Nicole C Schmitt, Justin Shapiro, Timothy B Shaver, Sandro J Stoeckli, Maie St John, William Alvo Stokes, Anita Sulibhavi, Jason Tasoulas, Varun Vendra, Daniel B Vinh, Celina G Virgen, Christian Wooten, Neil M Woody, Geoffrey D Young
IMPORTANCE: Postoperative radiation therapy for close surgical margins in low- to intermediate-grade salivary carcinomas lacks multi-institutional supportive evidence. OBJECTIVE: To evaluate the oncologic outcomes for low- and intermediate-grade salivary carcinomas with close and positive margins. DESIGN, SETTING, AND PARTICIPANTS: The American Head and Neck Society Salivary Gland Section conducted a retrospective cohort study from 2010 to 2019 at 41 centers...
December 14, 2023: JAMA Otolaryngology—Head & Neck Surgery
https://read.qxmd.com/read/38079314/clinical-efficacy-safety-and-complications-of-the-arthroscopic-cartilage-shaving-procedure-for-secondary-osmidrosis-treatment
#30
JOURNAL ARTICLE
Juo-Mei Chang, Yen-Chang Hsiao
BACKGROUND: Axillary osmidrosis is a common disease with negative psychosocial impact on patients. Further, many treatment modalities are not sufficient and result in recurrence. OBJECTIVE: We aimed to evaluate the effectiveness and safety of using a cartilage shaver in patients with recurrent osmidrosis to remove tightly attached apocrine glands and subdermal scars. METHODS: We retrospectively evaluated 24 patients with secondary axillary osmidrosis who underwent cartilage shaving surgery between January 2013 and May 2022...
December 1, 2023: Annals of Plastic Surgery
https://read.qxmd.com/read/38030484/comparison-of-dose-and-risk-estimates-between-iss-partner-agencies-for-a-30-day-lunar-mission
#31
JOURNAL ARTICLE
Mark R Shavers, Edward J Semones, Vyacheslav Shurshakov, Mikhail Dobynde, Tatsuhiko Sato, Tatsuto Komiyama, Leena Tomi, Jing Chen, Samy El-Jaby, Ulrich Straube, Chunsheng Li, Werner Rühm
The International Partner Agencies of the International Space Station (ISS) present a comparison of the ionizing radiation absorbed dose and risk quantities used to characterize example missions in lunar space. This effort builds on previous collaborative work that characterizes radiation environments in space to support radiation protection for human spaceflight on ISS in low-Earth orbit (LEO) and exploration missions beyond (BLEO). A "shielded" ubiquitous galactic cosmic radiation (GCR) environment combined with--and separate from--the transient challenge of a solar particle event (SPE) was modelled for a simulated 30-day mission period...
November 28, 2023: Zeitschrift Für Medizinische Physik
https://read.qxmd.com/read/38024814/arthroscopic-debridement-of-the-ankle-in-synovitis
#32
JOURNAL ARTICLE
Mohammad Jesan Khan, Naiyer Asif, Mohd Hadi Aziz, Siraj Ahmed Hasham Shaikh, Faiza Banu Siddiqui, Khwaja Moizuddin, Shibili Nuhmani
Inflammation and hypertrophy of the ankle joint's synovial lining can occur due to various causes. Chronic pain and degenerative changes may be due to synovitis causing clinical manifestations through traction on the joint capsule. The failure of conservative treatment for at least six months indicates arthroscopic debridement, which can provide significant pain relief without the morbidity of extensive surgical exposures. This study was therefore conducted to establish the functional results of arthroscopic debridement of the ankle joint in synovitis...
August 2023: Journal of Medicine and Life
https://read.qxmd.com/read/38023508/sustainable-formulation-polymers-for-home-beauty-and-personal-care-challenges-and-opportunities
#33
REVIEW
Christina A R Picken, Orla Buensoz, Paul D Price, Christopher Fidge, Laurie Points, Michael P Shaver
As society moves towards a net-zero future, the need to adopt more sustainable polymers is well understood, and as well as plastics, less visible formulation polymers should also be included within this shift. As researchers, industries and consumers move towards more sustainable products there is a clear need to define what sustainability means in fast moving consumer goods and how it can be considered at the design stage. In this perspective key challenges in achieving sustainable formulation polymers are highlighted, and opportunities to overcome them are presented...
November 22, 2023: Chemical Science
https://read.qxmd.com/read/38016149/successes-of-a-focused-mothers-own-milk-mom-program-in-counteracting-unintended-effects-of-a-donor-milk-program-on-mom-rates-at-discharge
#34
JOURNAL ARTICLE
Karen D Hendricks-Muñoz, Nada Darwish, Nayef Chahin, Shoshana Newman-Lindsay, Lisa Shaver, Melissa Dollings, Jie Xu, Valerie Coleman
Background: Avoidance of early formula feeding (EFF) and advancement of mother's own milk (MOM) in very low birth weight (VLBW) infants are important health influencers to decrease serious morbidities. Objective: To present the challenges and feeding strategy successes implemented to counteract a decline in MOM at discharge after initiation of donor milk (DM) to avoid EFF in racially and ethnically diverse VLBW infants. Patients and Methods: Retrospective review of prospectively tracked inborn surviving VLBW infants and their mothers admitted to neonatal intensive care unit from 2010 to 2020 during three feeding strategy implementations baby friendly (BF), DM program, and MOM bundle...
December 2023: Breastfeeding Medicine
https://read.qxmd.com/read/37995320/sars-cov-2-transmission-risk-for-common-group-activities-and-settings-a-living-scoping-review
#35
JOURNAL ARTICLE
Niyati Vyas, Alexandria Bennett, Nicole Shaver, Andrew Beck, Gabriele Zitiktye, Barbara Whelan, Rhea O'Regan, Aileen Conway, Becky Skidmore, David Moher, Julian Little
BACKGROUND: While the modes of transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are well studied, the risk of transmission in various group settings or activities is less clear. This living scoping review aims to summarize the risk factors of coronavirus disease 2019 (COVID-19) spread in common group activities (e.g. social gatherings) or settings (e.g. schools, hospitals, shared workplaces) to understand the drivers of transmission and to inform a risk assessment profile tool for use of rapid antigen detection tests...
February 5, 2024: European Journal of Public Health
https://read.qxmd.com/read/37991487/cell-free-hemoglobin-triggers-macrophage-cytokine-production-via-tlr4-and-myd88
#36
JOURNAL ARTICLE
Kaitlyn R Schaaf, Stuart R Landstreet, Sangami Pugazenthi, Emily Y Qian, Nathan D Putz, Tatiana Siderova, Allison M Owen, Julia K Bohannon, Lorraine B Ware, Julie A Bastarache, Ciara M Shaver
Cell-free hemoglobin (CFH) is elevated in the airspace of patients with acute respiratory distress syndrome (ARDS) and is sufficient to cause acute lung injury in a murine model. However, the pathways through which CFH causes lung injury are not well understood. Toll-like receptor 4 (TLR4) is a mediator of inflammation after detection of damage- and pathogen-associated molecular patterns. We hypothesized that TLR4 signaling mediates the pro-inflammatory effects of CFH in the airspace. After intra-tracheal CFH, BALBc mice deficient in TLR4 had reduced inflammatory cell influx into the airspace (bronchoalveolar lavage [BAL] cell counts, median TLR4KO:0...
November 22, 2023: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://read.qxmd.com/read/37952192/bag-valve-mask-ventilation-and-survival-from-out-of-hospital-cardiac-arrest-a-multicenter-study
#37
MULTICENTER STUDY
Ahamed H Idris, Elisabete Aramendi Ecenarro, Brian Leroux, Xabier Jaureguibeitia, Betty Y Yang, Sarah Shaver, Mary P Chang, Tom Rea, Peter Kudenchuk, Jim Christenson, Christian Vaillancourt, Clifton Callaway, David Salcido, Jonas Carson, Jennifer Blackwood, Henry E Wang
BACKGROUND: Few studies have measured ventilation during early cardiopulmonary resuscitation (CPR) before advanced airway placement. Resuscitation guidelines recommend pauses after every 30 chest compressions to deliver ventilations. The effectiveness of bag-valve-mask ventilation delivered during the pause in chest compressions is unknown. We sought to determine: (1) the incidence of lung inflation with bag-valve-mask ventilation during 30:2 CPR; and (2) the association of ventilation with outcomes after out-of-hospital cardiac arrest...
December 5, 2023: Circulation
https://read.qxmd.com/read/37948711/optimization-of-power-assisted-adenoidectomy-in-children-using-shaver-tips-of-various-modification
#38
JOURNAL ARTICLE
Anatolii L Kosakovskyi, Kateryna V Liakh, Yaroslav V Shkorbotun
OBJECTIVE: The aim: To study the efficacy of surgical treatment of patients with adenoid vegetations by implementing a differential method for choosing a tip for endo-scopic power-assisted adenoidectomy in children depending on dentition. PATIENTS AND METHODS: Materials and methods: We investigated the presence of nasal air emissions in 127 children (2-12 years old) before and after the operation. We excluded 12 patients due to the presence of nasal air emission before the operation...
2023: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://read.qxmd.com/read/37948099/a-deep-dive-into-instagram-s-top-skinfluencers
#39
JOURNAL ARTICLE
Hadley Johnson, Claire Herzog, Rob L Shaver, Sara A Hylwa
We characterized skinfluencers from various training backgrounds and compared their posts on Instagram featuring skin care products.
November 10, 2023: JMIR dermatology
https://read.qxmd.com/read/37931800/blinatumomab-therapy-is-associated-with-favorable-outcomes-after-allogeneic-hematopoietic-cell-transplant-in-pediatric-patients-with-b-cell-acute-lymphoblastic-leukemia
#40
JOURNAL ARTICLE
Gabriela Llaurador, Kristen Shaver, Mengfen Wu, Tao Wang, Amanda Gillispie, Erin Doherty, John Craddock, Jay Read, Khaled Yassine, Erin Morales, Anil George, David Steffin, Robert Krance, Caridad Martinez, Helen Heslop, Baheyeldin Salem
BACKGROUND: Blinatumomab, a bispecific T-cell engager that binds CD19 in leukemic cells and CD3 in cytotoxic T-cells and leads to leukemic blast lysis, is often used in pediatric patients with relapsed/refractory B-cell acute lymphoblastic leukemia (R/R-B-ALL) prior to allogeneic hematopoietic cell transplant (allo-HCT). Concerns about the potential risk of Blinatumomab-related immune-mediated toxicities after allo-HCT have not been adequately addressed. These include graft-versus-host disease (GVHD), delayed engraftment and graft failure or rejection...
November 4, 2023: Transplantation and cellular therapy
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