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Jake McClements, Michael Patrick Shaver, Khellil Sefiane, Vasileios Koutsos
We studied the morphology of poly(styrene-co-butadiene) random copolymers on a graphite surface. Polymer solutions were spin coated onto graphite, at various concentrations and molecular weights. The polymer films and nanostructures were imaged using atomic force microscopy. Above the overlap concentration, thin films formed. However, total wetting did not occur, despite the polymers being well above their T_g. Instead, dewetting was observed suggesting the films were in a state of metastable equilibrium. At lower concentrations, the polymers formed networks, nanoislands, and nanoribbons...
May 14, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
Libo Yu-Taeger, Viktoria Gaiser, Larissa Lotzer, Tina Roenisch, Benedikt Timo Fabry, Janice Stricker-Shaver, Nicolas Casadei, Michael Walter, Martin Schaller, Olaf Riess, Huu Phuc Nguyen, Thomas Ott, Kathrin Grundmann-Hauser
A three-base-pair deletion in the human TOR1A gene is causative for the most common form of primary dystonia, the early-onset dystonia type 1 (DYT1 dystonia). The pathophysiological consequences of this mutation are still unknown.To study the pathology of the mutant torsinA (TOR1A) protein, we have generated a transgenic rat line that overexpresses the human mutant protein under the control of the human TOR1A promoter. This new animal model was phenotyped with several approaches, including behavioral tests and neuropathological analyses...
May 8, 2018: Biology Open
Saame Raza Shaikh, Patti R Shaver, Brian M Shewchuk
SCOPE: Dietary fat composition can modulate gene expression in peripheral tissues in obesity. Observations of the dysregulation of growth hormone (GH) in obesity indicate that these effects extend to the hypothalamic-pituitary (H-P) axis. We thus determined whether specific high fat (HF) diets influenced the levels of Gh and other key gene transcripts in the H-P axis. METHODS AND RESULTS: C57BL/6 mice were fed a lean control diet or a HF diet in the absence or presence of OA, EPA or DHA ethyl esters...
May 8, 2018: Molecular Nutrition & Food Research
Albert Edward Telfeian
One complication associated with recombinant human bone morphogenetic protein (rhBMP-2) use in minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) is heterotopic bone growth at the neural foramen which results in the compression of neural structures. Here we present an awake, minimally invasive surgical approach for treating the radiculopathy that results from this excessive bone growth in the foramen. A 42-year-old male underwent a lumbar 4-sacral 1 MIS-TLIF by another surgeon. He did well in the initial postoperative period, but he began to note right leg pain and numbness in an L5 dermatomal pattern...
March 2018: Journal of Spine Surgery (Hong Kong)
John Shaver
No abstract text is available yet for this article.
April 2018: ANS. Advances in Nursing Science
Ciara M Shaver
No abstract text is available yet for this article.
April 24, 2018: American Journal of Respiratory Cell and Molecular Biology
Limin Kung, R D Shaver, R J Grant, R J Schmidt
The goal of making silage is to produce a stable feed with a high recovery of dry matter, energy, and highly digestible nutrients compared with the fresh crop. Microbial fermentation in the silo produces an array of end products and can change many nutritive aspects of a forage. High-quality silage should be void of undesirable compounds that could negatively affect animal performance, the environment, or net farm income. This review discusses the interpretation of the common fermentation end products, microbial populations, organoleptic properties, and changes in nutritive aspects of silages during storage of silages with emphasis on a North American perspective...
May 2018: Journal of Dairy Science
L F Ferraretto, R D Shaver, B D Luck
Over the last 25 years, whole-plant corn silage has become an important and popular feedstuff for dairy production. Copious research has been dedicated to the development and evaluation of alternatives to enhance the nutritive value of whole-plant corn silage. These efforts have been aimed at manipulating the physical and chemical characteristics of whole-plant corn silage in an effort to maximize dairy profitability. Results from this review indicate that optimization of harvest maturity, kernel processing, theoretical length of cut, and cutting height improve or maintain the nutritive value and milk production of lactating dairy cows...
May 2018: Journal of Dairy Science
Helen C Lam, Christie M Thomas, Julia M Shaver
No abstract text is available yet for this article.
April 1, 2018: American Family Physician
Z Mwaniki, M Neijat, E Kiarie
We examined egg production and quality responses of adding up to 7.5% defatted black soldier fly larvae meal (BSFLM) in a corn-soybean meal diet fed to pullets (19 to 27 wk of age). The concentration of CP and crude fat in BSFLM sample was 59.3 and 7.0% DM, respectively. A corn-soybean meal diet was formulated with 0 or 5.0 or 7.5% BSFLM and fed (n = 6) to a total of 108, 19-wk-old Shaver White pullets placed in conventional cages (6 birds/cage). The birds had free access to feed and water. Hen-day egg production (HDEP) and average egg weight were monitored daily and feed intake (FI) weekly...
April 13, 2018: Poultry Science
Taasin Srivastava, Parham Diba, Justin M Dean, Fatima Banine, Daniel Shaver, Matthew Hagen, Xi Gong, Weiping Su, Ben Emery, Daniel L Marks, Edward N Harris, Bruce Baggenstoss, Paul H Weigel, Larry S Sherman, Stephen A Back
Cerebral white matter injury (WMI) persistently disrupts myelin regeneration by oligodendrocyte progenitor cells (OPCs). We identified a specific bioactive hyaluronan fragment (bHAf) that downregulates myelin gene expression and chronically blocks OPC maturation and myelination via a tolerance-like mechanism that dysregulates pro-myelination signaling via AKT. Desensitization of AKT occurs via TLR4 but not TLR2 or CD44. OPC differentiation was selectively blocked by bHAf in a maturation-dependent fashion at the late OPC (preOL) stage by a noncanonical TLR4/TRIF pathway that induced persistent activation of the FoxO3 transcription factor downstream of AKT...
May 1, 2018: Journal of Clinical Investigation
Matthew A Struckhoff, Carl E Orazio, Donald E Tillitt, David K Shaver, Diana M Papoulias
Palmyra Atoll, once a WWII U.S. Navy air station, is now a U.S. National Wildlife Refuge with nearly 50km2 of coral reef and 275ha of emergent lands with forests of Pisonia grandis trees and colonies of several bird species. Due to the known elemental and organic contamination from chemicals associated with aviation, power generation and transmission, waste management, and other air station activities, a screening survey to map elemental concentrations was conducted. A map of 1944 Navy facilities was georeferenced and identifiable features were digitized...
March 2018: Marine Pollution Bulletin
Xue-Yan Liu, Keisuke Koba, Lina A Koyama, Sarah E Hobbie, Marissa S Weiss, Yoshiyuki Inagaki, Gaius R Shaver, Anne E Giblin, Satoru Hobara, Knute J Nadelhoffer, Martin Sommerkorn, Edward B Rastetter, George W Kling, James A Laundre, Yuriko Yano, Akiko Makabe, Midori Yano, Cong-Qiang Liu
Plant nitrogen (N) use is a key component of the N cycle in terrestrial ecosystems. The supply of N to plants affects community species composition and ecosystem processes such as photosynthesis and carbon (C) accumulation. However, the availabilities and relative importance of different N forms to plants are not well understood. While nitrate (NO3 - ) is a major N form used by plants worldwide, it is discounted as a N source for Arctic tundra plants because of extremely low NO3 - concentrations in Arctic tundra soils, undetectable soil nitrification, and plant-tissue NO3 - that is typically below detection limits...
March 27, 2018: Proceedings of the National Academy of Sciences of the United States of America
Ferrin C Wheeler, Annette S Kim, Claudio A Mosse, Aaron C Shaver, Ashwini Yenamandra, Adam C Seegmiller
Objectives: Acute myeloid leukemia (AML) is classified in part by recurrent cytogenetic abnormalities, often detected by both fluorescent in situ hybridization (FISH) and karyotype. The goal of this study was to assess the utility of FISH and karyotyping at diagnosis and follow-up. Methods: Adult AML samples at diagnosis or follow-up with karyotype and FISH were identified. Concordance was determined, and clinical characteristics and outcomes for discordant results were evaluated...
March 29, 2018: American Journal of Clinical Pathology
D M Jacobs, W-Y Leung, D Essi, W Park, A Shaver, J Claus, C Ruh, G G Rao
Outpatient parenteral antimicrobial therapy (OPAT) programmes facilitate hospital discharge, but patients remain at risk of complications and consequent healthcare utilisation (HCU). Here we elucidated the incidence of and risk factors associated with HCU in OPAT patients. This was a retrospective, single-centre, case-control study of adult patients discharged on OPAT. Cases (n = 63) and controls (n = 126) were patients that did or did not utilise the healthcare system within 60 days. Characteristics associated with HCU in bivariate analysis (P ≤ 0...
April 2018: Epidemiology and Infection
Phillip R Shaver, Mario Mikulincer, Jude Cassidy
According to attachment theory, a sense of attachment security (confidence that others will be available and supportive when needed) facilitates the functioning of the caregiving behavioral system and the empathic provision of care to suffering others. In this article we review what has been learned during the last decade about attachment-related individual differences in caregiving within couple relationships and prosocial behavior in the wider world. We begin with a brief account of attachment theory and the dynamic interplay of the attachment and caregiving behavioral systems...
February 16, 2018: Current Opinion in Psychology
Daniel R Kunzler, Pejma Shazadeh Safavi, Brittney J Warren, Cory F Janney, Vinod Panchbhavi
Synovial chondromatosis of the ankle is rare and sparsely documented. Traditional surgical intervention is open loose body excision and synovectomy. Upon literature review, only two other cases were found to be managed arthroscopically. We report a case of synovial chondromatosis in a 54-year-old man leading to pain and limited range of motion of his ankle. This unique case of extensive nodule formation was treated via a three-port arthroscopic approach. Removal of loose bodies and synovectomy were successfully performed arthroscopically...
December 23, 2017: Curēus
M Bohnsack
OBJECTIVE: Complete arthroscopic decompression of the impinging subspinal soft tissues and resection of the hypertrophic bone formation between the anterior hip capsule and the anterior inferior iliac spine (AIIS) or decompression of a hypertrophic AIIS. INDICATIONS: Painful anterior hip impingement and decreased hip flexion following a hypertrophic osseous subspinal deformation. CONTRAINDICATIONS: No clinical symptoms or decreased anterior hip function despite radiological osseous subspinal hip impingement...
April 2018: Operative Orthopädie und Traumatologie
Mario Mikulincer, Phillip R Shaver
According to attachment theory, individual differences in the availability and responsiveness of close relationship partners, beginning in infancy, and the resulting formation of fairly stable attachment orientations are crucial for understanding the ways people experience and regulate emotions. In this article, we review what has been learned during the last decade about attachment-related individual differences in emotion regulation. We begin with a brief account of the hypothesized links between different forms of attachment insecurity (anxiety, avoidance) and strategies people use in regulating distress and coping with threatening events...
February 14, 2018: Current Opinion in Psychology
Arianna Palmieri, Johann R Kleinbub, Vincenzo Calvo, Enrico Benelli, Irene Messina, Marco Sambin, Alberto Voci
Physiological synchronization (PS) is a phenomenon of simultaneous activity between two persons' physiological signals. It has been associated with empathy, shared affectivity, and efficacious therapeutic relationships. The aim of the present study was to explore the possible connections between PS and the attachment system, seeking preliminary evidence of this link by means of an experimental manipulation of the sense of attachment security in psychotherapists according to a protocol by Mikulincer and Shaver (2001), which has been proven to elicit empathetic behavior...
March 1, 2018: Journal of Counseling Psychology
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