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https://www.readbyqxmd.com/read/27922165/excess-mortality-during-the-warm-summer-of-2015-in-switzerland
#1
Ana M Vicedo-Cabrera, Martina S Ragettli, Christian Schindler, Martin Röösli
QUESTION UNDER STUDY: In Switzerland, summer 2015 was the second warmest summer for 150 years (after summer 2003). For summer 2003, a 6.9% excess mortality was estimated for Switzerland, which corresponded to 975 extra deaths. The impact of the heat in summer 2015 in Switzerland has not so far been evaluated. METHODS: Daily age group-, gender- and region-specific all-cause excess mortality during summer (June-August) 2015 was estimated, based on predictions derived from quasi-Poisson regression models fitted to the daily mortality data for the 10 previous years...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/27921174/spatiotemporal-variations-of-extreme-low-temperature-for-emergency-transport-a-nationwide-observational-study
#2
Daisuke Onozuka, Akihito Hagihara
Although recent studies have investigated the effect of extreme heat on emergency transport, few have investigated the spatiotemporal variations of extreme low temperature for emergency transport on a national scale. Data pertaining to emergency ambulance transport and weather variation in the 47 prefectures of Japan between 2007 and 2010 were obtained. Nonlinear and delayed relationships between temperature and morbidity were assessed using a two-stage analysis. First, a Poisson regression analysis allowing for overdispersion in a distributed lag nonlinear model was used to estimate the prefecture-specific effects of temperature on morbidity...
December 5, 2016: International Journal of Biometeorology
https://www.readbyqxmd.com/read/27921099/thermoresponsive-microgels-containing-trehalose-as-soft-matrices-for-3d-cell-culture
#3
Małgorzata Burek, Sylwia Waśkiewicz, Anna Lalik, Sebastian Student, Tadeusz Bieg, Ilona Wandzik
A series of thermoresponsive glycomicrogels with trehalose in the cross-links or with trehalose in the cross-links and as pending moieties was synthesized. These materials were obtained by surfactant-free precipitation copolymerization of N-isopropylacrylamide and various amounts of trehalose monomers. The resultant particles showed a spherical shape and a submicrometer hydrodynamic size with a narrow size distribution. At 25 °C, glycomicrogels in solutions with physiological ionic strength formed stable colloids, which further gelled upon heating to physiological temperature forming a macroscopic hydrogel with an interconnected porous structure...
December 6, 2016: Biomaterials Science
https://www.readbyqxmd.com/read/27917868/examining-the-validity-of-the-phonon-gas-model-in-amorphous-materials
#4
Wei Lv, Asegun Henry
The idea of treating phonon transport as equivalent to transport through a gas of particles is termed the phonon gas model (PGM), and it has been used almost ubiquitously to try and understand heat conduction in all solids. However, most of the modes in disordered materials do not propagate and thus may contribute to heat conduction in a fundamentally different way than is described by the PGM. From a practical perspective, the problem with trying to apply the PGM to amorphous materials is the fact that one cannot rigorously define the phonon velocities for non-propagating modes, since there is no periodicity...
December 5, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27915403/a-simple-approach-for-the-development-of-urban-climatic-maps-based-on-the-urban-characteristics-in-tainan-taiwan
#5
Yu-Cheng Chen, Tzu-Ping Lin, Chien-Ting Lin
Motivated by the increasing thermal load in urban environment, this work established Urban Climatic map (UCmap) focusing on thermal environment issues based on urban development factors, e.g., land cover and building characteristics, representing thermal load of human body and ventilation path in the urban structures. In the established process of UCmap in this work, Tainan city, which is a highly developed city in southern Taiwan, is selected as the research area. A 50-m resolution grid is used to capture urban development factors and the climate data based on 1 year of mobile and fix-point measurements, from which the thermal load and the wind environment map are constructed...
December 3, 2016: International Journal of Biometeorology
https://www.readbyqxmd.com/read/27914995/transdermal-skin-patch-based-on-reduced-graphene-oxide-a-new-approach-for-photothermal-triggered-permeation-of-ondansetron-across-porcine-skin
#6
Florina Teodorescu, Gurvan Quéniat, Catherine Foulon, Marie Lecoeur, Alexandre Barras, Samia Boulahneche, Mohmaed Salah Medjram, Thomas Hubert, Amar Abderrahmani, Rabah Boukherroub, Sabine Szunerits
The development of a skin-mounted patch capable of controlled transcutaneous delivery of therapeutics through thermal activation provides a unique solution for the controlled release of active principles over long-term periods. Here, we report on a flexible transdermal patch for photothermal triggered release of ondansetron (ODS), a commonly used drug for the treatment of chemotherapy-induced nausea and vomiting and used as model compound here. To achieve this, a dispersion of ODS-loaded reduced graphene oxide (rGO-ODS) nanosheets were deposited onto Kapton to produce a flexible polyimide-based patch...
November 30, 2016: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/27911823/continuous-flow-synthesis-of-zsm-5-zeolite-on-the-order-of-seconds
#7
Zhendong Liu, Kotatsu Okabe, Chokkalingam Anand, Yasuo Yonezawa, Jie Zhu, Hiroki Yamada, Akira Endo, Yutaka Yanaba, Takeshi Yoshikawa, Koji Ohara, Tatsuya Okubo, Toru Wakihara
The hydrothermal synthesis of zeolites carried out in batch reactors takes a time so long (typically, on the order of days) that the crystallization of zeolites has long been believed to be very slow in nature. We herein present a synthetic process for ZSM-5, an industrially important zeolite, on the order of seconds in a continuous flow reactor using pressurized hot water as a heating medium. Direct mixing of a well-tuned precursor (90 °C) with the pressurized water preheated to extremely high temperature (370 °C) in the millimeter-sized continuous flow reactor resulted in immediate heating to high temperatures (240-300 °C); consequently, the crystallization of ZSM-5 in a seed-free system proceeded to completion within tens of or even several seconds...
November 28, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27910691/compact-ecei-system-with-in-vessel-reflective-optics-for-west
#8
Y B Nam, H K Park, W Lee, G S Yun, M Kim, R Sabot, D Elbeze, P Lotte, J Shen
An electron cyclotron emission imaging (ECEI) diagnostic system for WEST (W Environment for Steady state Tokamak) is under development to study the MHD instabilities affected by tungsten impurities. The system will provide 2-D Te fluctuation images (width × height = ∼18 cm × ∼ 34 cm at low field side and ∼13 cm × ∼ 39 cm at high field side) from a poloidal cross section with high spatial (≤1.7 cm) and temporal (≤2 μs) resolutions. While the key concept and electronic structure are similar to that of prior ECEI systems on other tokamak devices such as KSTAR, DIII-D, or ASDEX-U, part of the imaging optics have to be placed inside the vacuum vessel in order to resolve issues on limited installation space and longer beam path to the detector position...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910466/first-results-from-solid-state-neutral-particle-analyzer-on-experimental-advanced-superconducting-tokamak
#9
J Z Zhang, Y B Zhu, J L Zhao, B N Wan, J G Li, W W Heidbrink
Full function integrated, compact solid state neutral particle analyzers (ssNPA) based on absolute extreme ultraviolet silicon photodiode have been successfully implemented on the experimental advanced superconducting tokamak to measure energetic particle. The ssNPA system has been operated in advanced current mode with fast temporal and spatial resolution capabilities, with both active and passive charge exchange measurements. It is found that the ssNPA flux signals are increased substantially with neutral beam injection (NBI)...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910435/design-of-an-extreme-ultraviolet-spectrometer-suite-to-characterize-rapidly-heated-solid-matter
#10
S T Ivancic, C R Stillman, D Nelson, I A Begishev, C Mileham, P M Nilson, D H Froula
An ultrafast streaked extreme-ultraviolet (XUV) spectrometer (5-20 nm) was developed to measure the temperature dynamics in rapidly heated samples. Rapid heating makes it possible to create exotic states of matter that can be probed during their inertial confinement time-tens of picoseconds in the case of micron-sized targets. In contrast to other forms of pyrometry, where the temperature is inferred from bulk x-ray emission, XUV emission is restricted to the sample surface, allowing for a temperature measurement at the material-vacuum interface...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27898850/genetic-evaluations-for-growth-heat-tolerance-in-angus-cattle
#11
H L Bradford, B O Fragomeni, J K Bertrand, D A L Lourenco, I Misztal
The objectives were to assess the impact of heat stress and to develop a model for genetic evaluation of growth heat tolerance in Angus cattle. The American Angus Association provided weaning weight (WW) and yearling weight (YW) data, and records from the Upper South region were used because of the hot climatic conditions. Heat stress was characterized by a weaning (yearling) heat load function defined as the mean temperature-humidity index (THI) units greater than 75 (70) for 30 (150) d prior to the weigh date...
October 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27894884/modulation-of-the-heat-shock-response-is-associated-with-acclimation-to-novel-temperatures-but-not-adaptation-to-climatic-variation-in-the-ants-aphaenogaster-picea-and-a-rudis
#12
Sara Helms Cahan, Andrew D Nguyen, John Stanton-Geddes, Clint A Penick, Yainna Hernáiz-Hernández, Bernice B DeMarco, Nicholas J Gotelli
Ecological diversification into thermally divergent habitats can push species toward their physiological limits, requiring them to accommodate temperature extremes through plastic or evolutionary changes that increase persistence under the local thermal regime. One way to withstand thermal stress is to increase production of heat shock proteins, either by maintaining higher baseline abundance within cells or by increasing the magnitude of induction in response to heat stress. We evaluated whether environmental variation was associated with expression of three heat shock protein genes in two closely-related species of woodland ant, Aphaenogaster picea and A...
November 25, 2016: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/27893731/observation-of-extreme-phase-transition-temperatures-of-water-confined-inside-isolated-carbon-nanotubes
#13
Kumar Varoon Agrawal, Steven Shimizu, Lee W Drahushuk, Daniel Kilcoyne, Michael S Strano
Fluid phase transitions inside single, isolated carbon nanotubes are predicted to deviate substantially from classical thermodynamics. This behaviour enables the study of ice nanotubes and the exploration of their potential applications. Here we report measurements of the phase boundaries of water confined within six isolated carbon nanotubes of different diameters (1.05, 1.06, 1.15, 1.24, 1.44 and 1.52 nm) using Raman spectroscopy. The results reveal an exquisite sensitivity to diameter and substantially larger temperature elevations of the freezing transition (by as much as 100 °C) than have been theoretically predicted...
November 28, 2016: Nature Nanotechnology
https://www.readbyqxmd.com/read/27890732/programmed-near-infrared-light-responsive-drug-delivery-system-for-combined-magnetic-tumor-targeting-magnetic-resonance-imaging-and-chemo-phototherapy
#14
Qianhua Feng, Yuanyuan Zhang, Wanxia Zhang, Yongwei Hao, Yongchao Wang, Hongling Zhang, Lin Hou, Zhenzhong Zhang
: In this study, an intelligent drug delivery system was developed by capping doxorubicin (DOX)-loaded hollow mesoporous CuS nanoparticles (HMCuS NPs) with superparamagnetic iron oxide nanoparticles (IONPs). Under near infrared (NIR) light irradiation, the versatile HMCuS NPs could exploit the merits of both photothermal therapy (PTT) and photodynamic therapy (PDT) simultaneously. Herein, the multifunctional IONPs as gatekeeper with the enhanced capping efficiency were supposed to realize "zero premature release" and minimize the adverse side effects during the drug delivery in vivo...
November 24, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27888927/thermal-behavior-of-human-eye-in-relation-with-change-in-blood-perfusion-porosity-evaporation-and-ambient-temperature
#15
REVIEW
Aasma Rafiq, M A Khanday
Extreme environmental and physiological conditions present challenges for thermal processes in body tissues including multi-layered human eye. A mathematical model has been formulated in this direction to study the thermal behavior of the human eye in relation with the change in blood perfusion, porosity, evaporation and environmental temperatures. In this study, a comprehensive thermal analysis has been performed on the multi-layered eye using Pennes' bio-heat equation with appropriate boundary and interface conditions...
December 2016: Journal of Thermal Biology
https://www.readbyqxmd.com/read/27876889/harnessing-hyperthermostable-lactonase-from-sulfolobus-solfataricus-for-biotechnological-applications
#16
Benjamin Rémy, Laure Plener, Laetitia Poirier, Mikael Elias, David Daudé, Eric Chabrière
Extremozymes have gained considerable interest as they could meet industrial requirements. Among these, SsoPox is a hyperthermostable enzyme isolated from the archaeon Sulfolobus solfataricus. This enzyme is a lactonase catalyzing the hydrolysis of acyl-homoserine lactones; these molecules are involved in Gram-negative bacterial communication referred to as quorum sensing. SsoPox exhibits promiscuous phosphotriesterase activity for the degradation of organophosphorous chemicals including insecticides and chemical warfare agents...
November 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27873767/high-pressure-studies-with-x-rays-using-diamond-anvil-cells
#17
Guoyin Shen, Ho Kwang Mao
Pressure profoundly alters all states of matter. The symbiotic development of ultrahigh-pressure diamond anvil cells, to compress samples to sustainable multi-megabar pressures; and synchrotron x-ray techniques, to probe materials' properties in situ, has enabled the exploration of rich high-pressure (HP) science. In this article, we first introduce the essential concept of diamond anvil cell technology, together with recent developments and its integration with other extreme environments. We then provide an overview of the latest developments in HP synchrotron techniques, their applications, and current problems, followed by a discussion of HP scientific studies using x-rays in the key multidisciplinary fields...
November 22, 2016: Reports on Progress in Physics
https://www.readbyqxmd.com/read/27870065/photoacclimatory-and-photoprotective-responses-to-cold-versus-heat-stress-in-high-latitude-reef-corals
#18
Stefanie Pontasch, Paul L Fisher, Thomas Krueger, Sophie Dove, William Leggat, Ove Hoegh-Guldberg, Simon K Davy
Corals at the world's southernmost coral reef of Lord Howe Island (LHI) experience large temperature and light fluctuations and need to deal with periods of cold temperature (< 18 °C), but few studies have investigated how corals are able to cope with these conditions. Our study characterized the response of key photophysiological parameters, as well as photoacclimatory and photoprotective pigments (chlorophylls, xanthophylls and β-carotene), to short-term (5-day) cold stress (~ 15 °C; 7 °C below control) in three LHI coral species hosting distinct Symbiodinium ITS2 types, and compared the coral-symbiont response to that under elevated temperature (~ 29 °C; 7 °C above control)...
November 21, 2016: Journal of Phycology
https://www.readbyqxmd.com/read/27867789/the-phenology-of-arctic-ocean-surface-warming
#19
Michael Steele, Suzanne Dickinson
In this work, we explore the seasonal relationships (i.e., the phenology) between sea ice retreat, sea surface temperature (SST), and atmospheric heat fluxes in the Pacific Sector of the Arctic Ocean, using satellite and reanalysis data. We find that where ice retreats early in most years, maximum summertime SSTs are usually warmer, relative to areas with later retreat. For any particular year, we find that anomalously early ice retreat generally leads to anomalously warm SSTs. However, this relationship is weak in the Chukchi Sea, where ocean advection plays a large role...
September 2016: Journal of Geophysical Research. Oceans
https://www.readbyqxmd.com/read/27865528/integrating-new-indicators-of-predictors-that-shape-the-public-s-perception-of-local-extreme-temperature-in-china
#20
Jie Ban, Lei Huang, Chen Chen, Yuming Guo, Mike Z He, Tiantian Li
The public's risk perception of local extreme heat or cold plays a critical role in community health and prevention under climate change. However, there is limited evidence on such issues in China where extreme weather is occurring more frequently due to climate change. Here, a total of 2500 residents were selected using a three-step sampling method and investigated by a questionnaire in two representative cities. We investigated risk perception of extreme heat in Beijing and extreme cold in Harbin in 2013, aiming to examine their possible correlations with multiple epidemiological factors...
November 16, 2016: Science of the Total Environment
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