keyword
https://read.qxmd.com/read/38226724/pharmacological-interventions-for-the-prevention-of-bleeding-in-people-undergoing-elective-hip-or-knee-surgery-a-systematic-review-and-network-meta-analysis
#21
REVIEW
Victoria N Gibbs, Rita Champaneria, Josie Sandercock, Nicky J Welton, Louise J Geneen, Susan J Brunskill, Carolyn Dorée, Catherine Kimber, Antony Jr Palmer, Lise J Estcourt
BACKGROUND: Hip and knee replacement surgery is a well-established means of improving quality of life, but is associated with a significant risk of bleeding. One-third of people are estimated to be anaemic before hip or knee replacement surgery; coupled with the blood lost during surgery, up to 90% of individuals are anaemic postoperatively. As a result, people undergoing orthopaedic surgery receive 3.9% of all packed red blood cell transfusions in the UK. Bleeding and the need for allogeneic blood transfusions has been shown to increase the risk of surgical site infection and mortality, and is associated with an increased duration of hospital stay and costs associated with surgery...
January 16, 2024: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/38211729/increased-rate-of-complications-following-total-knee-arthroplasty-in-patients-who-have-polymyositis
#22
JOURNAL ARTICLE
Elizabeth Driskill, Zhichang Zhang, Jialun Chi, Quanjun Cui
BACKGROUND: Polymyositis (PM) is a systemic connective tissue disorder that can lead to early onset degenerative joint disease and a need for total knee arthroplasty (TKA). Outcomes of TKA in patients who have PM are not well-documented in the literature. The purpose of this study was to evaluate PM as a risk factor for complications after TKA. METHODS: Using a national private payer insurance database from 2010 to 2022, PM patients undergoing primary TKA were compared to 10:1 matched controls based on age, sex, and comorbidities...
January 9, 2024: Journal of Arthroplasty
https://read.qxmd.com/read/38204648/redo-aortic-surgery-does-one-versus-multiple-affect-outcomes
#23
JOURNAL ARTICLE
Elizabeth L Norton, Kanika Kalra, Bradley G Leshnower, Jane W Wei, Jose N Binongo, Edward P Chen
OBJECTIVE: Redo aortic surgery has a higher risk of morbidity and mortality because it is technically complex due to mediastinal adhesions, infection, and previously implanted prostheses. In this study, we sought to benchmark our single-center experience comparing outcomes in patients undergoing aortic surgery after 1 versus multiple previous cardiac operations. METHODS: Between 2004 and 2019, 429 patients underwent redo aortic surgery. They were classified as aortic surgery after 1 previous surgery (first redo surgery, n = 360) and aortic surgery after 2 or more (multiple) previous surgeries (multiple redo surgery, n = 69)...
December 2023: JTCVS open
https://read.qxmd.com/read/38192948/cerebrovascular-events-and-hospital-discharge-outcomes-associated-with-drug-use-a-retrospective-case-matched-study
#24
JOURNAL ARTICLE
Richard T Rogers, Ha Tran, Starlie C Belnap, Amy K Starosciak
Introduction Individuals using cocaine, methamphetamines, cannabis, and other mood-altering drugs (MADs) have been reported to have greater stroke risk when compared to individuals who do not use these drugs. Yet, the impact that MAD use has on stroke outcomes has not been adequately explored, with existing research not agreeing on the extent to which the use of these drugs influences stroke outcomes. This study aimed to determine the impact that the use of common MADs has on stroke outcome factors such as length of stay (LOS), discharge modified Rankin Scale (mRS), and discharge disposition...
December 2023: Curēus
https://read.qxmd.com/read/38167231/use-of-computed-tomography-coronary-calcium-score-for-prediction-of-cardiovascular-events-in-cancer-patients-a-retrospective-cohort-analysis
#25
JOURNAL ARTICLE
Sinal Patel, Francisco X Franco, Malcolm McDonald, Carlos Rivera, Bernardo Perez-Villa, Patrick Collier, Rohit Moudgil, Neha Gupta, Diego B Sadler
BACKGROUND: CT- coronary calcium score, is one of the most studied and widely available modalities in cardiovascular medicine. Coronary artery calcium score (CACS) is an established predictor of coronary artery disease. The 'standard of care' diagnostic modality to measure CACS is ECG-gated Cardiac Multi-Detector Computed Tomography. There is convincing evidence of a strong association between CACS and major cardiovascular (CV) events in asymptomatic individuals. Cancer patients (C) may have a higher risk for CV disease than non-cancer patients (NC) related not only to cancer treatments but also to shared biological factors and pathways...
January 2, 2024: Cardio-Oncology
https://read.qxmd.com/read/38165875/a-prospective-observational-study-of-estimating-drug-related-problems-and-clinical-outcomes-in-subtypes-of-stroke-patients
#26
JOURNAL ARTICLE
Muhammad Ali, Muhammad Harris Shoaib, Shagufta Nesar, Muhammad Jamal, Sabiha Gul, Saira Shahnaz, Shoaib Nawaz, Quratulain Khan, Javaria Imran
BACKGROUND: Stroke is a neurological disease and a leading cause of mortality worldwide. Strokes mainly consist of two types: hemorrhage and ischemia. Stroke patients are being administered multiple drug therapy and are at risk of drug-related problems. AIM: To estimate drug-related problems (DRPs) and clinical end outcomes in hospitalized stroke patients. METHODS: Current study was a multicenter, cross-sectional prospective observational study including 250 stroke patients admitted to tertiary care hospitals in Karachi, Pakistan...
2024: PloS One
https://read.qxmd.com/read/38157996/association-between-heart-failure-and-arteriovenous-access-patency-in-patients-with-end-stage-renal-disease-on-hemodialysis
#27
JOURNAL ARTICLE
Andrea T Fisher, Bianca Mulaney, Brian M Sheehan, Manuel Garcia-Toca, Ehab Sorial, Michael D Sgroi
INTRODUCTION: Heart disease and chronic kidney disease are often comorbid conditions due to shared risk factors including diabetes and hypertension. However, the effect of congestive heart failure on arteriovenous fistula and graft patency rates is poorly understood. We hypothesize preexisting heart failure may diminish blood flow to the developing AV fistula and worsen patency. METHODS: We conducted a single-institution retrospective review of 412 patients with ESRD who underwent hemodialysis access creation from 2015-2021...
December 27, 2023: Journal of Vascular Surgery
https://read.qxmd.com/read/38156594/cardiovascular-toxicity-of-angiogenesis-inhibitors-among-patients-with-cancer-in-taiwan-a-nested-case-control-study
#28
JOURNAL ARTICLE
Yen-Chou Chen, Chun-Yao Huang, Li-Ming Lien, Jin-Hua Chen, Fang-I Hsieh
BACKGROUND: Research on the cardiovascular toxicity of angiogenesis inhibitors among patients with cancer in Taiwan is lacking. This observational study explored the risk of major adverse cardiovascular events (MACEs) associated with angiogenesis inhibitors in Taiwan. METHODS AND RESULTS: We conducted a nested case-control study using the TCR (Taiwan Cancer Registry) linked with the Taiwan National Insurance Claim Database. We matched every case with 4 controls using risk-set sampling by index date, age, sex, cancer type, and cancer diagnosis date...
December 29, 2023: Journal of the American Heart Association
https://read.qxmd.com/read/38155137/comorbid-pathology-in-fatal-cases-due-to-coronavirus-disease-covid-19-in-victims-of-the-chornobyl-npp-accident
#29
JOURNAL ARTICLE
V O Sushko, D A Bazyka, O O Kolosynska, L M Zvarych
INTRODUCTION: The victims of the Chornobyl accident, as well as whole population of Ukraine, have become the object of the COVID-19 pandemic in today's conditions. As of 01.01.2020, 108,898 victims had documented permanent disability (persons with disabilities) and, as a rule, suffered from 4-6 types of non-tumor chronic diseases of internal organs, primarily the circulatory system, as well as oncological and endocrine pathology, that significantly affect the course of COVID-19 in a severe scenario and contribute to death...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38149388/-long-term-lung-protection-of-probiotics-in-children-with-sepsis-and-its-mechanism
#30
RANDOMIZED CONTROLLED TRIAL
Yu Wang, Huijie Song, Fanfan Du, Zhongwen Yang, Yanli Wang
OBJECTIVE: To observe the effects of probiotics supplementation on the natural killer T cell (NKT cell) and inflammatory factors in children with sepsis and its protective effect on long-term lung function. METHODS: A total of 100 children with sepsis admitted to the department of pediatric intensive care unit (PICU) of Henan Provincial People's Hospital from March 2021 to May 2022 were selected as the research objects. The children were randomly divided into placebo group and probiotic group, 50 cases in each group...
December 2023: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://read.qxmd.com/read/38143660/a-multifactorial-case-of-stevens-johnson-syndrome-with-atypical-features
#31
Jennifer M Paterno, Zach Breslow, Mufit A Mamo, Edgar Mercado
Stevens-Johnson syndrome (SJS) is a severe mucocutaneous reaction that has a broad spectrum of causes and risk factors that include medications and other infectious causes such as Mycoplasma . In this case report, a patient with multiple comorbidities that confounded the presentation of Stevens-Johnson syndrome is observed. The patient was a 29-year-old female with a past medical history of recurrent cerebrovascular accident (CVA) who presented for an evaluation of chest pain. After empiric vancomycin was started for suspicion of endocarditis, our patient developed altered mental status, mucositis, and a painful erythematous erosion on her chest concerning for vasculitis, but after treatment and pathological review, it was found to be Stevens-Johnson syndrome...
November 2023: Curēus
https://read.qxmd.com/read/38137144/clinical-features-and-risk-factors-of-postoperative-stroke-in-adult-moyamoya-disease
#32
JOURNAL ARTICLE
Wen Liu, Kaixin Huang, Jianjian Zhang, Da Zhou, Jincao Chen
BACKGROUND AND PURPOSE: The clinical features of and risk factors for postoperative stroke after surgical revascularization in adult moyamoya disease (MMD) have not been fully elucidated. To this end, the baseline clinical features were hereby described, and the risk factors for postoperative stroke were determined. METHODS: Data of 4078 MMD inpatients were collected retrospectively across all secondary- and higher-level hospitals of Hubei Province from January 2019 to December 2020...
December 8, 2023: Brain Sciences
https://read.qxmd.com/read/38108793/risk-factors-modification-in-atrial-fibrillation-a-brief-review
#33
JOURNAL ARTICLE
Sukhbir Randhawa, Subrat Da, Wilbert S Aronow
INTRODUCTION: Atrial fibrillation (AF) is a supraventricular arrhythmia characterized by fibrillatory waves in the atria with an irregular ventricular rhythm. It is the most common arrhythmia treated in clinical practice. AF is associated with approximately five-fold increase in risk of cerebrovascular accident (stroke) and two-fold increase in cognitive dysfunction and all-cause mortality. AREAS COVERED: Multiple risk factors have been identified for development of AF including age, hypertension, diabetes, and obesity...
December 18, 2023: Expert Review of Cardiovascular Therapy
https://read.qxmd.com/read/38103814/cardiovascular-disease-burden-in-the-middle-east-and-north-africa-region
#34
REVIEW
Laith Alhuneafat, Omar Al Ta'ani, Ahmad Jabri, Tala Tarawneh, Adee ElHamdan, Abdallah Naser, Farah Al-Bitar, Nada Alrifai, Fares Ghanem, Khaldoon Alaswad, Mohammad Alqarqaz, Jeremy R Van't Hof, Selcuk Adabag, Salim S Virani
INTRODUCTION: Cardiovascular disease (CVD) remains the leading cause of death globally, including the Middle East and North Africa (MENA) region. However, limited research has been conducted on the burden of CVD in this region. Our study aims to investigate the burden of CVD and related risk factors in the MENA. METHODS: We used data from the Global Burden of Disease (GBD) 2019 to examine CVD prevalence in 21 MENA countries. Prevalence and mortality were analyzed using Bayesian regression tools, demographic methods, and mortality-to-incidence ratios...
December 14, 2023: Current Problems in Cardiology
https://read.qxmd.com/read/38071662/postoperative-thrombocytopenia-and-subsequent-consequences-in-acute-type-a-aortic-dissection
#35
JOURNAL ARTICLE
Zhiwei Tang, Yongfeng Shao
OBJECTIVES: To ascertain if postoperative thrombocytopenia following open aortic surgery with a median sternotomy can predict early- and intermediate-term morbidity and mortality. METHODS: From January 2018 to December 2022, a comparison was made between patients who had and didn't have postoperative thrombocytopenia (defined as a nadir < 75 × 103/μL after 72 h of open aortic surgery with median sternotomy). Intermediate-term mortality during follow-up was the main result, with cerebrovascular accident and acute renal injury requiring dialysis as secondary events...
2023: Annals of Medicine
https://read.qxmd.com/read/38068387/a-novel-model-to-predict-inadequate-bowel-preparation-prior-to-colonoscopy-incorporating-patients-reactions-to-drinking-the-laxative
#36
JOURNAL ARTICLE
Daniela Malkin, Daniel L Cohen, Vered Richter, Eran Ariam, Sergei Vosko, Haim Shirin, Anton Bermont
BACKGROUND AND AIMS: Prior studies have identified predictors of inadequate preparation with limited success. We aimed to build a model that could predict the likelihood of inadequate preparation by also including factors related to the patient's reaction to drinking the laxative preparation. METHODS: Demographic, clinical, and preparation-related data were prospectively collected on patients undergoing colonoscopy. An inadequate preparation was defined as a Boston Bowel Preparation Scale < 6...
November 26, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/38061238/blunt-cerebrovascular-injury-complications-in-aging-adults-a-national-trauma-database-study
#37
JOURNAL ARTICLE
Rosa Negash, Holly Baselice, Shruthi Srinivas, Mehak Chawla, Andrew J Young
INTRODUCTION: Blunt cerebrovascular injury (BCVI) is defined as a nonpenetrating injury to the carotid or vertebral arteries which can be highly morbid. Because BCVI is rare, most studies have been devoted to triaging trauma patients for BCVI identification, with little data available regarding the complications these patients experience after initial evaluation. Here, we analyze the association of complications during admission for BCVI patients. METHODS: The National Trauma Databank was queried from 2007 to 2014 for adults ≥65 y old...
December 6, 2023: Journal of Surgical Research
https://read.qxmd.com/read/38056723/risks-following-total-knee-arthroplasty-in-patients-who-have-antiphospholipid-syndrome
#38
JOURNAL ARTICLE
Zhichang Zhang, Jialun Chi, Ian Duensing, Huzaifah Qureshi, Quanjun Cui
BACKGROUND: Antiphospholipid syndrome (APS) is recognized as a thrombophilic autoimmune condition characterized by a tendency to develop venous thromboembolism. Total knee arthroplasty (TKA) is a prevalent procedure in patients who have advanced knee arthritis. Notably, TKA is unequivocally considered a thrombotic risk factor. However, outcomes of APS patients after TKA are still poorly documented in literature. The purpose of this study was to evaluate APS as a potential risk factor for complications after TKA...
December 4, 2023: Journal of Arthroplasty
https://read.qxmd.com/read/38050581/a-discussion-of-the-contemporary-prediction-models-for-atrial-fibrillation
#39
JOURNAL ARTICLE
Michael A Rosenberg, Joseph Adewumi, Ryan G Aleong
Atrial Fibrillation is a complex disease state with many environmental and genetic risk factors. While there are environmental factors that have been shown to increase an individual's risk of atrial fibrillation, it has become clear that atrial fibrillation has a genetic component that influences why some patients are at a higher risk of developing atrial fibrillation compared to others. This review will first discuss the clinical diagnosis of atrial fibrillation and the corresponding rhythm atrial flutter...
October 2023: Medical Research Archives
https://read.qxmd.com/read/38040097/incidence-of-nerve-injury-following-acupuncture-treatments-in-taiwan
#40
JOURNAL ARTICLE
Chia-Lin Lin, Andy Chern, Ming-Jen Wang, Shun-Ku Lin
OBJECTIVE: Acupuncture, a widely employed traditional therapeutic modality known for its efficacy in pain alleviation and diverse condition management, may inadvertently result in mechanical nerve injury due to its invasive nature. This research aimed to ascertain the incidence of nerve injuries post-acupuncture, identify associated risk factors, and map the distribution of nerve injury sites. METHODS: A case-control study nested in the National Health Insurance Research Database (NHIRD) 2000-2018 two million cohort was conducted...
November 29, 2023: Complementary Therapies in Medicine
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