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https://www.readbyqxmd.com/read/27925227/an-erp-study-of-response-inhibition-in-the-auditory-domain-in-children-with-fetal-alcohol-spectrum-disorders
#1
Matthew M Gerhold, Sandra W Jacobson, Joseph L Jacobson, Christopher D Molteno, Ernesta M Meintjes, Colin M Andrew
BACKGROUND: Previous event-related potential (ERP) studies of response inhibition in children with fetal alcohol spectrum disorder (FASD) have used a visual Go/NoGo task to study the impact of prenatal alcohol exposure on response inhibition. No studies exist using auditory versions of the task; thus, it is unclear how the deficits observed in visual tasks translate into the auditory domain. METHODS: This study examined ERPs using an auditory Go/NoGo paradigm in a sample of 35 school-age children-18 with heavy prenatal alcohol exposure and 17 normally developing controls...
December 7, 2016: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/27925055/lung-protection-an-intervention-for-tidal-volume-reduction-in-a-teaching-intensive-care-unit
#2
Arturo Briva, Cristina Gaiero
Objective: To determine the effect of feedback and education regarding the use of predicted body weight to adjust tidal volume in a lung-protective mechanical ventilation strategy. Methods: The study was performed from October 2014 to November 2015 (12 months) in a single university polyvalent intensive care unit. We developed a combined intervention (education and feedback), placing particular attention on the importance of adjusting tidal volumes to predicted body weight bedside...
December 1, 2016: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/27924444/bindings-in-working-memory-the-role-of-object-based-attention
#3
Zaifeng Gao, Fan Wu, Fangfang Qiu, Kaifeng He, Yue Yang, Mowei Shen
Over the past decade, it has been debated whether retaining bindings in working memory (WM) requires more attention than retaining constituent features, focusing on domain-general attention and space-based attention. Recently, we proposed that retaining bindings in WM needs more object-based attention than retaining constituent features (Shen, Huang, & Gao, 2015, Journal of Experimental Psychology: Human Perception and Performance, doi: 10.1037/xhp0000018 ). However, only unitized visual bindings were examined; to establish the role of object-based attention in retaining bindings in WM, more emperical evidence is required...
December 6, 2016: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/27923417/mechanisms-of-memory-dysfunction-during-high-altitude-hypoxia-training-in-military-aircrew
#4
Daniel A Nation, Mark W Bondi, Ellis Gayles, Dean C Delis
OBJECTIVES: Cognitive dysfunction from high altitude exposure is a major cause of civilian and military air disasters. Pilot training improves recognition of the early symptoms of altitude exposure so that countermeasures may be taken before loss of consciousness. Little is known regarding the nature of cognitive impairments manifesting within this critical window when life-saving measures may still be taken. Prior studies evaluating cognition during high altitude simulation have predominantly focused on measures of reaction time and other basic attention or motor processes...
December 7, 2016: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/27923149/the-effect-of-cerebral-asymmetries-and-eye-scanning-on-pseudoneglect-for-a-visual-search-task
#5
Michael E R Nicholls, Amelia Hobson, Joanne Petty, Owen Churches, Nicole A Thomas
Pseudoneglect is the tendency for the general population to over-attend to the left. While pseudoneglect is classically demonstrated using line bisection, it also occurs for visual search. The current study explored the influence of eye movements and functional cerebral asymmetry on asymmetries for visual search. In Experiment 1, 24 participants carried out a conjunction search for a target within a rectangular array. A leftward advantage for detecting targets was observed when the eyes were free to move, but not when they were restricted by short exposure durations...
December 3, 2016: Brain and Cognition
https://www.readbyqxmd.com/read/27922659/eye-movement-analysis-and-cognitive-assessment-the-use-of-comparative-visual-search-tasks-in-a-non-immersive-vr-application
#6
Pedro J Rosa, Pedro Gamito, Jorge Oliveira, Diogo Morais, Matthew Pavlovic, Olivia Smyth, Inês Maia, Tiago Gomes
BACKGROUND: An adequate behavioral response depends on attentional and mnesic processes. When these basic cognitive functions are impaired, the use of non-immersive Virtual Reality Applications (VRAs) can be a reliable technique for assessing the level of impairment. However, most non-immersive VRAs use indirect measures to make inferences about visual attention and mnesic processes (e.g., time to task completion, error rate). OBJECTIVES: To examine whether the eye movement analysis through eye tracking (ET) can be a reliable method to probe more effectively where and how attention is deployed and how it is linked with visual working memory during comparative visual search tasks (CVSTs) in non-immersive VRAs...
December 6, 2016: Methods of Information in Medicine
https://www.readbyqxmd.com/read/27922339/responding-to-emotional-scenes-effects-of-response-outcome-and-picture-repetition-on-reaction-times-and-the-late-positive-potential
#7
Nina N Thigpen, Andreas Keil, Alexandra M Freund
Processing the motivational relevance of a visual scene and reacting accordingly is crucial for survival. Previous work suggests the emotional content of naturalistic scenes affects response speed, such that unpleasant content slows responses whereas pleasant content accelerates responses. It is unclear whether these effects reflect motor-cognitive processes, such as attentional orienting, or vary with the function/outcome of the motor response itself. Four experiments manipulated participants' ability to terminate the picture (offset control) and, thereby, the response's function and motivational value...
December 6, 2016: Cognition & Emotion
https://www.readbyqxmd.com/read/27921860/effects-of-cognitive-remediation-therapy-on-neurocognition-and-negative-symptoms-in-schizophrenia-an-italian-naturalistic-study
#8
Mariangela Lanfredi, Giacomo Deste, Clarissa Ferrari, Stefano Barlati, Laura Rosa Magni, Roberta Rossi, Luca de Peri, Marco Bonomi, Giuseppe Rossi, Antonio Vita
INTRODUCTION: Cognitive remediation therapy (CRT) has been reported to positively affect neurocognitive processes among patients with schizophrenia; however, the degree to which changes in cognition is linked to improved clinical symptoms, remains poorly understood. The current study aimed to investigate whether cognitive gains were associated to improvements in negative symptoms' severity in patients with schizophrenia living in two Italian psychiatric facilities. METHODS: Patients with a diagnosis of schizophrenia were consecutively assigned to CRT (n = 33) and compared with an historical control group (n = 28)...
December 6, 2016: Cognitive Neuropsychiatry
https://www.readbyqxmd.com/read/27921281/colorful-hydrophobic-poly-vinyl-butyral-cationic-dye-fibrous-membranes-via-a-colored-solution-electrospinning-process
#9
Xu Yan, Ming-Hao You, Tao Lou, Miao Yu, Jun-Cheng Zhang, Mao-Gang Gong, Fu-Yan Lv, Yuan-Yuan Huang, Yun-Ze Long
Colorful nanofibrous membranes have attracted much attention for their visual varieties and various functionalities. In this article, a colored solution electrospinning process was used to fabricate colorful hydrophobic poly(vinyl butyral) (PVB)/cationic dye nanofibrous membranes (NFMs) successfully. The color and morphology of these as-spun nanofibrous membranes have been analyzed by colorimetry, spectroscopy, and scanning electron microscopy (SEM). It is shown that the as-spun colorful PVB-based membranes exhibit excellent level-dyeing property and color stability...
December 2016: Nanoscale Research Letters
https://www.readbyqxmd.com/read/27919855/uncoupling-protein-2-deficiency-reduces-proliferative-capacity-of-murine-pancreatic-stellate-cells
#10
Sarah Muller, Sandra Maria Klingbeil, Andreea Sandica, Robert Jaster
BACKGROUND: Uncoupling protein 2 (UCP2) has been suggested to inhibit mitochondrial production of reactive oxygen species (ROS) by decreasing the mitochondrial membrane potential. Experimental acute pancreatitis is associated with increased UCP2 expression, whereas UCP2 deficiency retards regeneration of aged mice from acute pancreatitis. Here, we have addressed biological and molecular functions of UCP2 in pancreatic stellate cells (PSCs), which are involved in pancreatic wound repair and fibrogenesis...
December 2016: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/27919677/an-individual-differences-approach-to-multiple-target-visual-search-errors-how-search-errors-relate-to-different-characteristics-of-attention
#11
Stephen H Adamo, Matthew S Cain, Stephen R Mitroff
Multiple-target visual searches, where more than one target can be present within a single search array, are especially error-prone such that a second target is more likely to be missed after a first target has been detected. Increasingly, evidence supports a resource depletion account of these errors-a first target consumes attentional resources leaving fewer available to process a second target. However, "attention" is broadly defined and is composed of many different characteristics, leaving considerable uncertainty about how attention affects second-target detection...
December 2, 2016: Vision Research
https://www.readbyqxmd.com/read/27919548/cognitive-decline-over-time-in-adults-with-myotonic-dystrophy-type-1-a-9-year-longitudinal-study
#12
Benjamin Gallais, Cynthia Gagnon, Jean Mathieu, Louis Richer
Myotonic dystrophy type 1 (DM1) is an inherited neuromuscular disease with multisystemic involvement including the central nervous system. The evolution of the cognitive profile is a matter of debate, whether an eventual decline could be global or process-specific. Study aims are to describe, compare and document the clinical relevance of the progression of cognitive abilities in DM1 patients with adult and late-onset phenotypes. A total of 115 DM1 patients (90 adult; 25 late-onset) were assessed twice within a 9-year period on cognitive abilities (language, memory, visual attention, processing speed, visuoconstructive abilities and executive functions) and intellectual functioning (WAIS-R 7)...
October 14, 2016: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/27918894/perception-of-ensemble-statistics-requires-attention
#13
Molly Jackson-Nielsen, Michael A Cohen, Michael A Pitts
To overcome inherent limitations in perceptual bandwidth, many aspects of the visual world are represented as summary statistics (e.g., average size, orientation, or density of objects). Here, we investigated the relationship between summary (ensemble) statistics and visual attention. Recently, it was claimed that one ensemble statistic in particular, color diversity, can be perceived without focal attention. However, a broader debate exists over the attentional requirements of conscious perception, and it is possible that some form of attention is necessary for ensemble perception...
December 2, 2016: Consciousness and Cognition
https://www.readbyqxmd.com/read/27916671/leftward-bias-in-orienting-to-and-disengaging-attention-from-salient-task-irrelevant-events-in-rapid-serial-visual-presentation
#14
Kamila Śmigasiewicz, Nicole Westphal, Rolf Verleger
When embedded in the left or right stream of rapidly changing distractors, the second target (T2) is systematically better identified on the left than on the right. This left visual field advantage (LVFA) was recently attributed to better abilities of the right hemisphere in stimulus-driven orienting of attention: it was almost absent when salient uninformative cues were valid (presented in the T2 stream), and increased with invalid (different-stream) cues. However, cue-evoked negativity of event related potentials being earlier at the right than at the left hemisphere suggested that cues also are unequally processed, thereby possibly contributing to increased LVFA after invalid cues...
December 1, 2016: Neuropsychologia
https://www.readbyqxmd.com/read/27916665/task-modulations-and-clinical-manifestations-in-the-brain-functional-connectome-in-1615-fmri-datasets
#15
Tobias Kaufmann, Dag Alnæs, Christine Lycke Brandt, Nhat Trung Doan, Karolina Kauppi, Francesco Bettella, Trine V Lagerberg, Akiah O Berg, Srdjan Djurovic, Ingrid Agartz, Ingrid S Melle, Torill Ueland, Ole A Andreassen, Lars T Westlye
OBJECTIVE: An abundance of experimental studies have motivated a range of models concerning the cognitive underpinnings of severe mental disorders, yet the conception that cognitive and brain dysfunction is confined to specific cognitive domains and contexts has limited ecological validity. Schizophrenia and bipolar spectrum disorders have been conceptualized as disorders of brain connectivity; yet little is known about the pervasiveness across cognitive tasks. METHOD: To address this outstanding issue of context specificity, we estimated functional network connectivity from fMRI data obtained during five cognitive tasks (0-back, 2-back, go/no-go, recognition of positive faces, negative faces) in 90 patients with schizophrenia, 97 patients with bipolar spectrum disorder, and 136 healthy controls, including 1615 fMRI datasets in total...
December 1, 2016: NeuroImage
https://www.readbyqxmd.com/read/27916497/the-diabeates-project-perceptual-affective-and-psychophysiological-effects-of-music-and-music-video-in-a-clinical-exercise-setting
#16
Jasmin C Hutchinson, Costas I Karageorghis, Jessica D Black
OBJECTIVES: The purpose of this study was to examine the effects of music and music-video on perceptual (attentional focus, rated perceived exertion), affective (affective valence and enjoyment) and psychophysiological (blood glucose, heart rate) variables in outpatients attending a diabetes exercise clinic. METHODS: Participants were 24 females (age = 66.0 ± 8.5 years) enrolled in a supervised exercise program for people with diabetes. They engaged in mixed-modality exercise sessions that included a standardized combination of flexibility, aerobic and resistance activities under conditions of music, music-video and control...
December 1, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27915313/update-on-blindness-due-to-retinopathy-of-prematurity-globally-and-in-india
#17
Hannah Blencowe, Sarah Moxon, Clare Gilbert
Retinopathy of prematurity (ROP), a well-known complication of preterm birth that can result in avoidable blindness and visual impairment, is especially sensitive to the quality of neonatal inpatient care and appropriate, well-monitored oxygen. In 2010, the annual incidence of blindness and visual impairment from ROP was estimated to be 32,200 cases worldwide. The greatest burden is seen in middle-income countries, particularly where coverage of neonatal inpatient care has expanded without due attention to the quality of care provided, and the neonatal nursing skills and training of those providing this care...
November 7, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27914043/a-revisit-to-quantitative-pet-with-18-f-fdopa-of-high-specific-activity-using-a-high-resolution-condition-in-view-of-application-to-regenerative-therapy
#18
Go Akamatsu, Akihito Ohnishi, Kazuki Aita, Hiroyuki Nishida, Yasuhiko Ikari, Masahiro Sasaki, Nobuo Kohara, Michio Senda
OBJECTIVE: With the advent of regenerative/cell therapy for Parkinson's disease (PD), (18)F-FDOPA has drawn new attention as a biomarker of the therapeutic that cannot be evaluated with radiopharmaceuticals for dopamine transporter. Since most previous (18)F-FDOPA PET studies were carried out many years ago with a PET scanner of lower resolution and with (18)F-FDOPA of low specific activity synthesized from (18)F-F2, we used a newer PET/CT scanner with a high-resolution condition and (18)F-FDOPA synthesized from (18)F-F(-) to re-evaluate this technique on normal subjects and patients with PD, together with D2 receptor imaging with (11)C-raclopride (RAC)...
December 2, 2016: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/27913817/the-contribution-of-response-conflict-multisensory-integration-and-body-mediated-attention-to-the-crossmodal-congruency-effect
#19
Francesco Marini, Daniele Romano, Angelo Maravita
The crossmodal congruency task is a consolidated paradigm for investigating interactions between vision and touch. In this task, participants judge the elevation of a tactile target stimulus while ignoring a visual distracter stimulus that may occur at a congruent or incongruent elevation, thus engendering a measure of visuo-tactile interference (crossmodal congruency effect, CCE). The CCE reflects perceptual, attentional, and response-related factors, but their respective roles and interactions have not been set out yet...
December 2, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/27913591/temporal-expectations-guide-dynamic-prioritization-in-visual-working-memory-through-attenuated-alpha-oscillations
#20
Freek van Ede, Marcel Niklaus, Anna C Nobre
: While working memory is generally considered a highly dynamic mnemonic store, popular laboratory tasks employed to understand its psychological and neural mechanisms (such as change detection and continuous reproduction) often remain relatively "static", involving the retention of a set number of items throughout a shared delay interval. In the current study, we investigated visual working memory in a more dynamic setting, and assessed: 1) whether internally guided temporal expectations can dynamically and reversibly prioritize individual mnemonic items at specific times at which they are deemed most relevant and 2) the neural substrates that support such dynamic prioritization...
December 2, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
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