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Psychiatry Updates

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https://www.readbyqxmd.com/read/28584345/anaesthesia-for-electroconvulsive-therapy-an-overview-with-an-update-on-its-role-in-potentiating-electroconvulsive-therapy
#1
REVIEW
Pavan Kumar Kadiyala, Lakshmi Deepthi Kadiyala
Despite advances in pharmacotherapy, electroconvulsive therapy (ECT) remains a mainstay treatment option in psychiatry since its introduction in 1930s. It can be used primarily in severe illnesses when there is an urgent need for treatment or secondarily after failure or intolerance to pharmacotherapy. The 'unmodified' technique of ECT was practised initially, with a high incidence of musculoskeletal complications. Several modifications including general anaesthesia and muscle relaxation are used to increase the safety and patient acceptability of ECT...
May 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28577603/beyond-reactive-attachment-disorder-how-might-attachment-research-inform-child-psychiatry-practice
#2
REVIEW
Neil W Boris, Kimberly Renk
This article provides an updated review of attachment research with a focus on how comprehensive clinical assessment and intervention informs the care of young children. Child psychiatrists can serve as an important part of care coordination teams working with young children who have histories of early maltreatment and/or disruption in caregiving whether or not the children they are seeing meet criteria for an attachment disorder. Child psychiatrists should be familiar with both comprehensive assessment and the recent attachment-based interventions and appreciate how pharmacotherapy can be a useful adjunctive intervention when intensive therapy alone is ineffective...
July 2017: Child and Adolescent Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/28574009/potential-biomarkers-for-bipolar-disorder-where-do-we-stand
#3
REVIEW
Rajesh Sagar, Raman Deep Pattanayak
Bipolar disorder (BD) is a severe, recurrent mood disorder, associated with a significant morbidity and mortality, with high rates of suicides and medical comorbidities. There is a high risk of mood disorders among the first-degree relatives of patients with BD. In the current clinical practice, the diagnosis of BD is made by history taking, interview and behavioural observations, thereby lacking an objective, biological validation. This approach may result in underdiagnosis, misdiagnosis and eventually poorer outcomes...
January 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28525731/erratum
#4
(no author information available yet)
Kisely S, Hall K. An updated meta-analysis of randomized controlled evidence for the effectiveness of community treatment orders. Can J Psychiatry. 2014;59(10):561-564. (Original DOI: 10.1177/070674371405901010) On page 563, Figure 1 was printed with incorrect values. The correct values for Figure 1 are below: [Figure: see text].
May 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28373686/an-update-on-stem-cell-biology-and-engineering-for-brain-development
#5
C J C Parr, S Yamanaka, H Saito
Two recent technologies, induced-pluripotent stem cells (iPSCs) and direct somatic reprogramming, have shown enormous potential for cell-based therapies against intractable diseases such as those that affect the central nervous system. Already, methods that generate most major cell types of the human brain exist. Whether the cell types are directly reprogrammed from human somatic cells or differentiated from an iPSC intermediate, the overview presented here demonstrates how these protocols vary greatly in their efficiencies, purity and maturation of the resulting cells...
June 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28282076/-concepts-applied-to-psychiatry-pharmacogenomics
#6
María A Zorrilla Zubilete
Pharmacogenetics studies the action of a drug in order to predict the response based on the genetic makeup of an individual. The objective of pharmacogenetic studies is to minimize the adverse effects and to ensure therapeutic benefit. Since psychotropic drugs have a high rate of variability in patient response, the aim of this paper is to update the pharmacogenetic concepts in psychopharmacology in a review that provides tools for rigorous analysis when prescribing a psychotropic drug. The purpose of clinical pharmacogenetic testing is to be able to distinguish between patients who are more or less responders to certain drugs, or on contrary, who are at increased risk for adverse events...
September 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28145143/an-update-on-neurostimulation-in-psychiatry-an-interview-with-prof-paul-fitzgerald
#7
Andrew Amos
No abstract text is available yet for this article.
February 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28119350/a-systematic-review-of-management-strategies-for-children-s-mental-health-care-in-the-emergency-department-update-on-evidence-and-recommendations-for-clinical-practice-and-research
#8
Amanda S Newton, Lisa Hartling, Amir Soleimani, Scott Kirkland, Michele P Dyson, Mario Cappelli
OBJECTIVE: Children with mental health crises require access to specialised resources and services which are not yet standard in general and paediatric EDs. In 2010, we published a systematic review that provided some evidence to support the use of specialised care models to reduce hospitalisation, return ED visits and length of ED stay. We perform a systematic review to update the evidence base and inform current policy statements. METHODS: Twelve databases and the grey literature were searched up to January 2015...
January 24, 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/28017817/toward-a-better-understanding-on-the-role-of-prediction-error-on-memory-processes-from-bench-to-clinic
#9
REVIEW
María C Krawczyk, Rodrigo S Fernández, María E Pedreira, Mariano M Boccia
Experimental psychology defines Prediction Error (PE) as a mismatch between expected and current events. It represents a unifier concept within the memory field, as it is the driving force of memory acquisition and updating. Prediction error induces updating of consolidated memories in strength or content by memory reconsolidation. This process has two different neurobiological phases, which involves the destabilization (labilization) of a consolidated memory followed by its restabilization. The aim of this work is to emphasize the functional role of PE on the neurobiology of learning and memory, integrating and discussing different research areas: behavioral, neurobiological, computational and clinical psychiatry...
December 23, 2016: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28006997/guidelines-for-biological-treatment-of-substance-use-and-related-disorders-part-1-alcoholism-first-revision
#10
Michael Soyka, Henry R Kranzler, Victor Hesselbrock, Siegfried Kasper, Jochen Mutschler, Hans-Jürgen Möller
These practice guidelines for the biological treatment of alcohol use disorders are an update of the first edition, published in 2008, which was developed by an international Task Force of the World Federation of Societies of Biological Psychiatry (WFSBP). For this 2016 revision, we performed a systematic review (MEDLINE/PUBMED database, Cochrane Library) of all available publications pertaining to the biological treatment of alcoholism and extracted data from national guidelines. The Task Force evaluated the identified literature with respect to the strength of evidence for the efficacy of each medication and subsequently categorised it into six levels of evidence (A-F) and five levels of recommendation (1-5)...
March 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/27990322/recent-advances-and-controversies-in-peripartum-depression
#11
Jennifer L Payne
PURPOSE OF REVIEW: The purpose of this review is to update readers on recent controversies and findings on the underlying biology and clinical management of peripartum depression. RECENT FINDINGS: Topics discussed include the discovery and replication of two epigenetic biomarkers of peripartum depression, two well controlled studies that do NOT find associations between in utero antidepressant exposure and cardiac defects and persistent pulmonary hypertension of the newborn and ongoing controversy on whether antidepressant use during pregnancy prevents peripartum depression and whether or not hormonal treatments have a place in the management of postpartum depression...
September 2016: Current Obstetrics and Gynecology Reports
https://www.readbyqxmd.com/read/27986430/computational-approaches-to-schizophrenia-a-perspective-on-negative-symptoms
#12
REVIEW
Lorenz Deserno, Andreas Heinz, Florian Schlagenhauf
Schizophrenia is a heterogeneous spectrum disorder often associated with detrimental negative symptoms. In recent years, computational approaches to psychiatry have attracted growing attention. Negative symptoms have shown some overlap with general cognitive impairments and were also linked to impaired motivational processing in brain circuits implementing reward prediction. In this review, we outline how computational approaches may help to provide a better understanding of negative symptoms in terms of the potentially underlying behavioural and biological mechanisms...
December 13, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27798176/behavioral-and-neural-signatures-of-reduced-updating-of-alternative-options-in-alcohol-dependent-patients-during-flexible-decision-making
#13
Andrea M F Reiter, Lorenz Deserno, Thomas Kallert, Hans-Jochen Heinze, Andreas Heinz, Florian Schlagenhauf
Addicted individuals continue substance use despite the knowledge of harmful consequences and often report having no choice but to consume. Computational psychiatry accounts have linked this clinical observation to difficulties in making flexible and goal-directed decisions in dynamic environments via consideration of potential alternative choices. To probe this in alcohol-dependent patients (n = 43) versus healthy volunteers (n = 35), human participants performed an anticorrelated decision-making task during functional neuroimaging...
October 26, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27785752/training-psychiatry-residents-in-psychotherapy-the-role-of-manualized-treatments
#14
REVIEW
Joshua Pagano, Brandon N Kyle, Toni L Johnson, Sy Atezaz Saeed
Evidence-based treatment and manualized psychotherapy have a recent but rich history. As interest and research have progressed, defining the role of treatment manuals in resident training and clinical practice has become more important. Although there is not a universal definition of treatment manual, most clinicians and researchers agree that treatment manuals are an essential piece of evidence-based therapy, and that despite several limitations, they offer advantages in training residents in psychotherapy...
October 27, 2016: Psychiatric Quarterly
https://www.readbyqxmd.com/read/27683966/sport-psychiatry-and-psychotherapeutic-intervention-circa-2016
#15
Mark A Stillman, Tyler Brown, Eva C Ritvo, Ira D Glick
The focus of this paper is to provide an update on the use of psychotherapy as a treatment in sport psychiatry, and the use of this approach to address common psychiatric issues encountered with this population. Specifically, family therapy, individual therapy, and group psychotherapy prescribed alone, or in combination with medication, will be examined as methods to manage issues/disorders often associated with athletes. These include obsessive-compulsive rituals and perfectionism, and aggressive and risky behaviours, such as gambling, infidelity, substance use, and suicidal ideation, narcissism, and aggression in the context of individual and team competitive sports...
December 2016: International Review of Psychiatry
https://www.readbyqxmd.com/read/27623121/-advocacy-for-the-establishment-of-a-comprehensive-strategy-to-reduce-the-burden-of-schizophrenic-disorders
#16
D Leguay
This article attempts to identify and put into perspective the different approaches that could globally prevent the suffering induced by schizophrenia, from the detection of early psychosis to the impact on individual and family functioning and emotional health. Schizophrenia causes, at the community level, a number of difficult consequences and associated costs, which likely could be reduced if specific strategies, already known and documented internationally, were applied. Two areas not explored in this article: the role of medication and the issue of suicide prevention...
October 2016: L'Encéphale
https://www.readbyqxmd.com/read/27485931/-psychosocial-therapies-in-severe-mental-illness-outlook-on-the-update-of-the-dgppn-s3-guideline
#17
Uta Gühne, Thomas Becker, Steffi Riedel-Heller
The Psychiatry Enquête turned 40 years old last year. The S3 guideline "Psychosocial therapies for severe mental illness" is considered to be the last milestone of the reform to date. This paper highlights new impulses resulting from the S3 guideline for psychiatric care and provides an outlook on the update, expected in 2017. Many of the interventions reported in the S3 guideline are now supported by a broader evidence base.
August 2016: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/27463033/psychiatric-medication-preferences-of-sports-psychiatrists
#18
Claudia L Reardon, Shane Creado
OBJECTIVES: When prescribing psychiatric medications to athletes, it is important to consider issues that are especially important for this population, including side effects, safety concerns, and anti-doping policies. Only one report, from 2000, describes the prescribing preferences of psychiatrists who work with athletes. This manuscript aims to update the findings from that report, so as to help inform prescribing practices of primary care physicians, psychiatrists, and other clinicians who work with athletes...
November 2016: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/27401940/clinical-trial-network-for-the-promotion-of-clinical-research-for-rare-diseases-in-japan-muscular-dystrophy-clinical-trial-network
#19
Reiko Shimizu, Katsuhisa Ogata, Akemi Tamaura, En Kimura, Maki Ohata, Eri Takeshita, Harumasa Nakamura, Shin'ichi Takeda, Hirofumi Komaki
BACKGROUND: Duchenne muscular dystrophy (DMD) is the most commonly inherited neuromuscular disease. Therapeutic agents for the treatment of rare disease, namely "orphan drugs", have recently drawn the attention of researchers and pharmaceutical companies. To ensure the successful conduction of clinical trials to evaluate novel treatments for patients with rare diseases, an appropriate infrastructure is needed. One of the effective solutions for the lack of infrastructure is to establish a network of rare diseases...
July 11, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27379966/developing-a-digital-medicine-system-in-psychiatry-ingestion-detection-rate-and-latency-period
#20
Deborah Profit, Shashank Rohatagi, Cathy Zhao, Ainslie Hatch, John P Docherty, Timothy S Peters-Strickland
BACKGROUND: A digital medicine system (DMS) has been developed to measure and report adherence to an atypical antipsychotic, aripiprazole, in psychiatric patients. The DMS consists of 3 components: ingestible sensor embedded in a medication tablet, wearable sensor, and secure mobile and cloud-based applications. An umbrella study protocol was designed to rapidly assess the technical performance and safety of the DMS in multiple substudies to guide the technology development. METHODS: Two sequential substudies enrolled 30 and 29 healthy volunteers between March-April 2014 and February-March 2015, respectively, to assess detection accuracy of the ingestible sensor by the DMS and the latency period between ingestion and detection of the ingestion by the wearable sensor or the cloud-based server...
September 2016: Journal of Clinical Psychiatry
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