Yujie Tong, Qiwei Wang, Xiao Wang, Yuxian Xiang, Long Cheng, Xiaodong Hu, Yun Chen, Luyao Huo, Yong Xu, Sha Liu
Late-life depression is one of the most damaging mental illnesses, disrupting the normal lives of older people by causing chronic illness and cognitive impairment. Patients with late-life depression, accompanied by changes in appetite, insomnia, fatigue and guilt, are more likely to experience irritability, anxiety and somatic symptoms. It increases the risk of suicide and dementia and is a major challenge for the public health systems. The current clinical assessment, identification and effectiveness assessment of late-life depression are primarily based on history taking, mental status examination and scale scoring, which lack subjectivity and precision...
March 26, 2024: Psychiatry Research. Neuroimaging