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Bladder pain

Joao Pimentel Torres, Nuno Morais, Agostinho Cordeiro, Estevao Lima
Lower urinary tract symptoms (LUTS) are a common complaint in the general population with great impact on the quality of life. Besides the classical pathologies, there are less common causes that must be considered in the treatment approach for patients with LUTS. We present the case of a 30-year-old patient with multiple emergency department episodes with dysuria, urinary frequency, suprapubic pain and an episode of acute urinary retention. The blood and urine tests only revealed increased systemic inflammatory parameters...
June 21, 2018: BMJ Case Reports
Alice Crane, Sudhir Isharwal, Hui Zhu
The field of urology encompasses all benign and malignant disorders of the urinary tract and male genital tract. Together, urological disorders convey a huge economic and patient quality-of-life burden. Furthermore, hospital acquired urinary tract infections are coming under scrutiny as a measure of hospital quality. Given the importance of these pathologies, there is much progress still to be made in drug delivery designed to minimize side effects while providing effective care. Bladder pathology, in particular poses a unique opportunity for the development of novel intravesical therapies that can avoid some of the pitfalls of systemic drug delivery...
June 20, 2018: Molecular Pharmaceutics
Andrea Bosio, Eugenio Alessandria, Ettore Dalmasso, Dario Peretti, Simone Agosti, Alessandro Bisconti, Paolo Destefanis, Roberto Passera, Paolo Gontero
PURPOSE: To evaluate in details the actual extent of double-J stent-related symptoms after semirigid (URS) and flexible (RIRS) ureteroscopy using a validated questionnaire. METHODS: We asked to complete the Ureteric Stent Symptoms Questionnaire (USSQ) to all stone patients undergoing URS or RIRS with stent placement from 2010 to 2015. Stent-related symptoms' prevalence, severity, and impact on daily life were analyzed using descriptive statistics and five-order Likert scales...
June 19, 2018: World Journal of Urology
Christian Kersten, Marte Grønlie Cameron, Svein Mjåland
Background Neuropathic pain remains a significant challenge with unsatisfactory therapeutic options. Its pathogenesis may involve the neuropathic triad of neuronal, glial and immune cells. Communication between these cells is possibly perpetuated by mitogen-activated protein kinase (MAPK)-signaling. For several years, we successfully treated a rectal cancer patient with the epithelial growth factor receptor (EGFR)-inhibitor cetuximab, for debilitating neuropathic pain due to progressive malignant invasion of the sacral plexus...
December 29, 2017: Scandinavian Journal of Pain
S Loving, T Thomsen, P Jaszczak, J Nordling
Background and purpose Female chronic pelvic pain is a significant clinical problem that burdens the health care services and work productivity, and leads to disability and reduced quality of life among the women affected. A recent systematic review reported worldwide prevalence rates for female chronic pelvic pain ranging from 2.1% to 24%. Our aim was to assess the prevalence, characteristics, and factors associated with chronic pelvic pain among women living in Denmark, and to compare these findings with a pain-free reference group...
December 29, 2017: Scandinavian Journal of Pain
Blake C Gruenberg, David Mortel, Amanda Bogie
Pediatric penile pain is an uncommon complaint and is associated with a wide differential diagnosis including infectious, inflammatory, traumatic, and idiopathic conditions. Penile fractures, anatomically known as rupture of the corpus cavernosum, are almost exclusively reported in sexually mature patients and usually involve forceful manipulation during sexual activity. Rupture of the corpus cavernosum is a true urologic emergency. Failure to recognize and treat rupture of the corpus cavernosum has been associated with residual penile angulation, persistent hematoma, abscess, erectile dysfunction, and fibrosis...
June 14, 2018: Pediatric Emergency Care
Kevin Duh, Michael G Funaro, William DeGouveia, Sonia Bahlani, Dominic Pappas, Souhel Najjar, Inna Tabansky, Robert Moldwin, Joel N H Stern
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a condition causing intense pelvic pain and urinary symptoms. While it is thought to affect millions of people and significantly impair quality of life, difficulty with diagnosis and a lack of reliably effective treatment options leave much progress to be made in managing this condition. We describe what is currently known about the immunological and neurological basis of this disease, focusing on the interactions between the immune and nervous system...
May 2018: Discovery Medicine
Amanda McIntyre, Brooke Benton, Shannon Janzen, Jerome Iruthayarajah, Joshua Wiener, Janice J Eng, Robert Teasell
STUDY DESIGN: Mapping Review. OBJECTIVE: The objective of this study was to map out and characterize the quantity and quality of all published spinal cord injury (SCI) randomized controlled trials (RCTs) with respect to number, sample size, and methodological quality between January 1970 and December 2016. SETTING: Not applicable. METHODS: A literature search of multiple research databases was conducted. Studies adhering to the following criteria were included: the research design was an RCT; written in English; participants were >18 years; and the sample was >50% SCI...
June 14, 2018: Spinal Cord
Edgar L Leclaire, Jennifer Duong, Rachel M Wykes, Kevin E Miller, Tessa L Winterton, Milan Bimali
BACKGROUND: Intravesical injection with onabotulinum toxin A (BTX-A) injection can be performed in-office under local anesthesia. Rectally administered pain medication presents a potentially feasible and previously uninvestigated adjunct to office-based anesthesia protocols. OBJECTIVES: The primary aim of this study was to determine whether adding a belladonna and opiate (BO) suppository to standard lidocaine instillation resulted in reduction of bladder injection pain during BTX-A injection procedure...
June 11, 2018: American Journal of Obstetrics and Gynecology
George J Francis, An Ngo-Huang, Laurence D Rhines, Eduardo Bruera
BACKGROUND: Sacral neoplasms often present as large masses that often require sacrectomy. Multiple sacral nerve roots may be compromised post-sacrectomy and postoperative complications may result in impaired mobility, pain, orthostasis, and neurogenic bowel and bladder. CASE REPORTS: CASE #1: 58 year-old female with a sacral solitary fibrous tumor underwent a high-level sacrectomy and bilateral gluteal muscle flaps. Her rehabilitation course included management of pain, orthostasis, and neurogenic bowel and bladder...
June 11, 2018: European Journal of Physical and Rehabilitation Medicine
Carmen Benitez, Javier Pérez-Jara, Luis Garcia-Paino, Teresa Montenegro, Encarnacion Martin, Arturo Vilches-Moraga
Intrapelvic mass formation as a result of particulate wear debris induced osteolysis is a recognised late complication of cementless total hip arthroplasty. Clinical presentation typically involves hip and/or leg pain resulting in functional impairment, and obstructive urinary symptoms developing 3-20 years after surgery. An acute confusional state has never been described in this scenario. We report the case of an 86-year-old gentleman with a diagnosis of dementia brought to our emergency department with an acute confusional state...
June 8, 2018: Age and Ageing
Katherine M Fischer, Michael Louie, Phillip Mucksavage
PURPOSE OF REVIEW: Ureteral stent placement is a very common urologic procedure and a necessary component of many minimally invasive surgeries including ureteroscopy. Despite its widespread use, stent placement results in bothersome urinary symptoms and pain in approximately 80% of patients. This review discusses the proposed mechanisms underlying ureteral stent-related symptoms and current approaches to symptom management and the evidence to support them. RECENT FINDINGS: Though it has been extensively studied, the exact cause of stent-related symptoms remains unknown but is likely related to irritation of the bladder by the distal curl of the stent and reflux of urine through the stent up to the renal pelvis and transmission of high pressures associated with this...
June 11, 2018: Current Urology Reports
Lotte Linnemann Rønfeldt, Dorthe Hjort Jakobsen, Henrik Kehlet, Henriette Lipczak, Kasper Wennerwaldt
INTRODUCTION: Clinical practice guidelines (CPGs) support enhanced post-operative recovery and decrease morbidity. In addition, patient information leaflets (PILs) are associated with enhanced overall outcomes and improved patient satisfaction. The aim of this study was to provide an overview of the quality of CPGs and PILs in cancer surgery departments undertaking pulmonary lobectomy, nephrectomy, cystectomy, whipples, colorectal and ovarian surgery. METHODS: We conducted a cross-sectional descriptive study within 44 surgical departments in six cancer subspecialties: lung (n = 4), kidney (n = 9), bladder (n = 5), pancreas (n = 4), colorectal (n = 18) and ovarian (n = 4)...
June 2018: Danish Medical Journal
Shameel Musthafa, Zia Aftab, Syed Muhammad Ali, Maneesh Khanna
Gallbladder volvulus (GBV) due to rotation of the gall bladder (GB) around its own mesentery is a rare surgical emergency and often identified intraoperatively. Typically, cholecystitis is the initial clinical diagnosis, but a high index of suspicion on imaging can alert the physician for the possibility of GBV requiring urgent surgical intervention. We describe a case of a young female patient with hypoplasia/atrophy of the posterior segment of the right liver lobe and a GB with no hepatic attachments but only mesenteric pedicle...
June 8, 2018: BMJ Case Reports
Márcio Augusto Averbeck, Andrei Krassioukov, Nikesh Thiruchelvam, Helmut Madersbacher, Mette Bøgelund, Yasuhiko Igawa
AIMS: Intermittent catheterization (IC) is the gold standard for bladder management in patients with chronic urinary retention. Despite its medical benefits, IC-users experience a negative impact on their quality of life (QoL). For health economics based decision making, this impact is normally measured using generic QoL measures (such as EQ-5D) that estimate a single utility score which can be used to calculate Quality-Adjusted Life Years (QALYs). But these generic measures may not be sensitive to all relevant aspects of QoL affected by intermittent catheters...
June 8, 2018: Journal of Medical Economics
Ryo Ataka, Shinsuke Sato, Kazuyosi Matsubara, Masakazu Takagi, Ichiro Chihara, Naoki Kohei, Koji Yoshimura
A 74-year-old man presented at our hospital with complaints of abdominal pain, nausea, and vomiting. He had undergone laparoscopic radical cystectomy and ileal conduit for urinary bladder cancer 1 month earlier. The patient had abdominal distention, resonant sounds on percussion, and diffuse abdominal tenderness without rebound or guarding. Abdominal CT revealed dilated jejunal loops herniated through a cord-like structure. Based on these findings, emergency surgery was performed, and intestinal dilatation into the space between the ureter, the ileal conduit, and the sacral bone was detected...
June 7, 2018: Asian Journal of Endoscopic Surgery
Ching-Chung Liang, Yi-Hao Lin, Wu-Chiao Hsieh, Lulu Huang
OBJECTIVE: To investigate urinary and psychological symptoms in patients with interstitial cystitis/bladder pain syndrome (IC/BPS) after intravesical hyaluronic acid (HA) treatment. MATERIALS AND METHODS: Thirty patients with newly diagnosed with IC/BPS undergoing 4 weekly intravesical HA instillations followed by 5 monthly instillations were recruited. Pre-treatment evaluation included a urinalysis and urinary culture, a 3-day voiding diary, and cystoscopy with hydrodistention of the bladder...
June 2018: Taiwanese Journal of Obstetrics & Gynecology
Jia-Fong Jhang, Han-Chen Ho, Yuan-Hong Jiang, Cheng-Ling Lee, Yuan-Hsiang Hsu, Hann-Chorng Kuo
BACKGROUND: Electron microscopy (EM) characteristics of the urothelium in interstitial cystitis/bladder pain syndrome (IC/BPS) and their association with clinical condition are unclear. METHODS: Ten IC/BPS patients who were admitted for hydrodistention and 5 patients with stress urinary incontinence (control patients) were enrolled. All patients provided detailed clinical histories and underwent urodynamic studies. Cystoscopic bladder biopsies were obtained and processed for transmission EM (TEM) and scanning EM (SEM)...
2018: PloS One
Yaya Ouattara, Joseph Koné
A 67 years old patient has consulted for hypogastric pain, associated with a pollakiuria running for more than 12 months. The medical story reported genital prolapse, some episodes of haematuria and dysuria. Pelvic ultrasound showed a voluminous image of lithiasic appearance with irregular borders. A cystotomy was performed under perimedullary anesthesia allowing the extraction of a giant bladder stone measuring 7.2 cm as major axis and 5.5 cm for small axis.
2018: Pan African Medical Journal
Ashley Cox
No abstract text is available yet for this article.
June 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
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