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https://www.readbyqxmd.com/read/27922040/functional-urological-disorders-a-sensitized-defence-response-in-the-bladder-gut-brain-axis
#1
REVIEW
Carsten Leue, Joanna Kruimel, Desiree Vrijens, Adrian Masclee, Jim van Os, Gommert van Koeveringe
Functional urological and gastrointestinal disorders are interrelated and characterized by a chronic course and considerable treatment resistance. Urological disorders associated with a sizeable functional effect include overactive bladder (OAB), interstitial cystitis/bladder pain syndrome (IC/BPS), and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Poor treatment outcomes might be attributable to untreated underlying psychological and psychiatric disorders, as the co-occurrence of functional urological and gastrointestinal disorders with mood and anxiety disorders is common...
December 6, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27919986/videoscopic-inguinal-iliac-obturator-lymph-node-dissection-new-videoscopic-technique-for-regional-lymphadenectomy-in-patients-with-melanoma
#2
Nicola Solari, Marco Gipponi, DI Somma Carmine Franco, Francesca Rè, Olcese Sonia, Sergio Bertoglio, Ferdinando Cafiero
AIM: The feasibility of videoscopic inguinal-iliac-obturator lymphadenectomy (VIIOL) was assessed in 20 patients with melanoma and compared with a retrospective sample of 24 patients undergoing standard 'open' technique (IIOL). RESULTS: No postoperative death occurred; the mean operative time was lower in the IIOL series (190 min vs. 302 min) but the quality of life was greatly improved in the VIIOL group thanks to earlier bladder catheter removal, no nasogastric suction, less pain, earlier mobilization, lower in-hospital stay, and earlier resumption of daily activities (27...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27919731/nerve-sparing-laparoscopic-colposacropexy-using-a-percutaneous-surgical-system-a-case-report
#3
Federico Romano, Francesco Legge, Giovanni Scambia, Maurizio Guido
STUDY OBJECTIVE: To evaluate the feasibility, efficacy and safeness of nerve-sparing laparoscopic colposacropexy performed with a minimally invasive approach by using 2,9 mm Percuvance(TM) Percutaneous Surgical System (PSS) (The Percuvance(TM) System, Teleflex Inc., USA). DESIGN: Step-by-step video demonstration of the surgical technique. The Internal Department Committee approved this study. The patient was adequately informed about the possible risks and benefits of this experimental technique and a written consent agreeing to undergo the described procedure was signed...
December 2, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27919140/-undifferentiated-prostate-cancer-treated-with-radiation-therapy
#4
Hiroto Osakabe, Kenji Tamura, Ichiro Yamasaki, Satoshi Fukata, Shingo Ashida, Makoto Hiroi, Masanobu Tanimura, Keiji Inoue, Taro Shuin
We describe a 75-year-old man with undifferentiated prostate cancer that was treated with radiation therapy. He presented at a nearby general hospital with dysuria and pain upon micturition. He was diagnosed with undifferentiated prostate cancer by a needle biopsy and referred to our hospital for further examination and treatment. Enhanced computed tomography and magnetic resonance images showed prostate cancer and right obturator lymph node metastasis measuring 2.5 cm. Cystoscopy and colonoscopy revealed direct invasion of the urinary bladder and rectum...
November 2016: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/27919130/-two-cases-of-spontaneous-rupture-of-the-urinary-bladder-associated-with-radiation-cystitis-repaired-with-omentum-covering
#5
Takahito Wakamiya, Tomomi Kuramoto, Takeshi Inagaki
We experienced two cases of spontaneous rupture of the urinary bladder associated with radiation cystitis. Case 1 and Case 2 were a 45-year-old female and a 71-year-old female, respectively. Both of them were admitted to our hospital with complaints of high grade fever and severe lower abdominal pain. They had a past history of total hysterectomy followed by radiationtherapy more than10 years ago. The cystography and the subsequent computed tomography revealed spontaneous rupture of the urinary bladder. We performed the operationto repair the perforationsite with omentum covering...
October 2016: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/27915472/pathomechanism-of-interstitial-cystitis-bladder-pain-syndrome-and-mapping-the-heterogeneity-of-disease
#6
REVIEW
Jia-Fong Jhang, Hann-Chorng Kuo
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a heterogeneous syndrome which is usually characterized by urinary frequency, nocturia, and bladder pain. Several pathomechanisms have been proposed, including uroepithelial dysfunction, mast cell activation, neurogenic inflammation, autoimmunity, and occult urinary tract infections. It is possible that an inflammatory process alters regulation of urothelial homeostasis and results in dysfunction of the bladder epithelium. Different phenotypes of IC/BPS have been explored including Hunner and non-Hunner type IC, hypersensitive bladder, and bladder pain both with and without functional somatic syndrome...
November 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/27898164/dexmedetomidine-reduces-catheter-related-bladder-discomfort-a-prospective-randomized-placebo-controlled-double-blind-study
#7
Yang Zhao Yun, Xu Jun Mei, Zhu Rong, Dai Ru Ping, Liu Lei
OBJECTIVE: To evaluate the efficacy of dexmedetomidine in preventing catheterrelated bladder discomfort (CRBD) in a postanesthesia care unit (PACU). METHODS: A total of 138 consecutive adult male patients, classified by the American Society of Anesthesiologists (ASA) as ASA class I and ASA class II, were scheduled for elective open upper-middle abdominal surgery. They were randomized into 2 groups, C and D, comprising 69 patients each. Group C was given a saline solution as placebo, and group D received dexmedetomidine...
December 2016: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/27898100/bladder-dysfunction-in-2016-new-insights-into-interstitial-cystitis-and-chronic-pelvic-pain-syndromes
#8
Jia-Fong Jhang, Hann-Chorng Kuo
No abstract text is available yet for this article.
November 29, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27894978/an-arterial-perihepatic-enhancement-caused-by-spontaneous-bladder-rupture
#9
Taku Harada, Yasuhiro Suyama, Yusuke Hiratsuka, Taro Shimizu
Spontaneous bladder rupture (SBR) is a rare but life threatening condition. Its diagnosis is challenging; symptoms might present solely as ascites during onset or with features of frank peritonitis. When SBR causes peritonitis, arterial perihepatic enhancement can be detected on a contrast computed tomography scan. SBR should be suspected when patients have acute abdominal pain and risk factors including previous pelvic irradiation, urethral catheterization, and binge alcohol drinking. We present the first case report of arterial perihepatic enhancement due to SBR...
November 25, 2016: Urology
https://www.readbyqxmd.com/read/27891404/is-there-any-impact-of-copper-intrauterine-device-on-female-sexual-functioning
#10
Sezen Bozkurt Koseoglu, Ruya Deveer, Melike Nur Akin, Ali Sami Gurbuz, Burcu Kasap, Huri Guvey
INTRODUCTION: Intrauterine Device (IUD) is the most preferred modern contraceptive method in Turkey. Female Sexual Dysfunction (FSD) is defined as lack of one or more of the components in the sexual response cycle which includes sexual desire, impaired arousal and inability achieving an orgasm or pain with intercourse. FSD has multi-factorial aetiology. Advanced age and menopause, fatigue and stress, psychiatric and neurologic disease, childbirth, pelvic floor or bladder dysfunction, endometriosis, uterine fibroids, hypertension obesity, medication and substances, hormonal contraceptives, relationship factors are known risk factors for FSD...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27890686/cardiac-and-skeletal-muscle-metastases-from-squamous-cell-carcinoma-of-the-bladder-positron-emission-tomography-computed-tomography-findings
#11
Luis Gorospe, Ernesto García-Santana, Pablo Jane-Soler, María Del Val Gómez-Martínez, Victoria Gómez-Dos-Santos, Isabel García-Gómez-Muriel, Raquel García-Latorre
We describe the positron emission tomography-computed tomography (PET-CT) findings of a patient who presented to the emergency room with chest pain and palpitations and underwent a radical cystectomy 6 months earlier because of a squamous cell carcinoma of the bladder (SCCB). Cardiac catheterization ruled out coronary artery occlusion, but PET-CT showed multiple F-18-fluorodeoxyglucose-avid lesions involving multiple skeletal muscles and the heart, consistent with metastases. A CT-guided biopsy of 1 skeletal muscle lesion confirmed a metastasis with the same pathologic features as the SCCB...
November 24, 2016: Urology
https://www.readbyqxmd.com/read/27876432/routine-deferred-computed-tomography-for-patients-with-suspected-urolithiasis-is-low-value-healthcare
#12
Ingvild M Rosenlund, Olav H Førde, Arthur Revhaug
OBJECTIVE: The aim of this study was to investigate the benefits of deferred routine computed tomography of the kidneys, ureters and bladder (CT KUB) for patients with a self-limiting episode of suspected urolithiasis. MATERIALS AND METHODS: The study comprised a case series of consecutive patients examined with deferred routine CT KUB for control of suspected urolithiasis. Patients examined with CT KUB at the University Hospital of North Norway, between 1 January 2010 and 31 December 2013, were included...
November 23, 2016: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/27874495/evolution-of-multiple-sclerosis-spasticity-associated-symptoms-latest-data
#13
Peter Flachenecker
In addition to muscle stiffness and increasing mobility restrictions, symptoms commonly associated with multiple sclerosis (MS) spasticity are spasms, sleep disturbances, pain, fatigue and bladder dysfunction. Treatment options include trigger factor avoidance, physiotherapy and antispasticity medication. Oral antispasticity agents commonly used in Germany are baclofen, tizanidine and gabapentin, but physician and patient satisfaction with their effectiveness is low. Over the past few years, randomized controlled trials, observational studies and registry data have demonstrated the positive risk:benefit profile of add-on 9-delta-tetra-hydrocannabinol:cannabidiol oromucosal spray for moderate-to-severe resistant MS spasticity...
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27871577/lack-of-electrical-interference-between-spinal-cord-stimulators-and-other-implanted-electrical-pulse-devices
#14
Alaa Abd-Elsayed, Ravi Grandhi, Harsh Sachdeva
Spinal cord stimulators (SCSs) have been used for decades to treat chronic pain. SCSs are often used to treat patients with chronic back pain caused by failed back surgery syndrome, patients with complex regional pain syndrome, or individuals who are not candidates for surgery. SCSs are a relative contraindication in patients with another electrical pulse device. We present 3 patients who received SCS despite having another implant in place. There was no interaction between devices. The first case was a patient with failed back surgery syndrome who had an implantable cardiac defibrillator and an SCS implant...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27868099/endourologic-and-open-ureterolithotomy-and-common-sheath-reimplant-for-large-bladder-and-distal-ureteral-calculi
#15
Madeline Cancian, Joseph Brito, Joseph Renzulli, Gyan Pareek
A twenty-eight-year-old female with a history of suprapubic pain and recurrent urinary tract infections presents for urology referral with a kidney, ureter, and bladder radiograph showing a 4.4 cm bladder calculus and 6.5 cm distal left ureteral stone. She underwent effective cystolitholapaxy of the bladder stone. Endourologic attempt (left ureteroscopy) was unsuccessful because of ureteral stone burden. Findings at ureteroscopy revealed a duplicated system on the left with the lower pole moiety joining just proximal to the ureteral orifice...
2016: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/27863071/the-putative-involvement-of-actin-binding-proteins-and-cytoskeleton-proteins-in-pathological-mechanisms-of-ketamine-cystitis-revealed-by-a-prospective-pilot-study-using-proteomic-approaches
#16
Hsueh-Hui Yang, Wei-Jun Zhai, Hann-Chorng Kuo
PURPOSE: Ketamine Cystitis (KC) among chronic ketamine young abusers has increased dramatically and it has brought attention for Urologists. The underlying pathophysiological mechanism(s) of KC is still unclear. Therefore, the purpose of this study was to elucidate the possible pathophysiological mechanism(s) of KC through proteomic techniques. EXPERIMENTAL DESIGN: Bladder tissues were obtained from 7 patients with KC, 7 patients with interstitial cystitis/bladder pain syndrome, and 5 control subjects who underwent videourodynamic study followed by augmentation enterocystoplasty to increase bladder capacity...
November 10, 2016: Proteomics. Clinical Applications
https://www.readbyqxmd.com/read/27856418/spinal-afferent-nerve-endings-in-visceral-organs-recent-advances
#17
Nick J Spencer, Vladimir P Zagorodnyuk, Simon J Brookes, Tim James Hibberd
Spinal afferent neurons play a major role in detection and transduction of painful stimuli from internal (visceral) organs. Recent technical advances have made it possible to visualize the endings of spinal afferent axons in visceral organs. Although it is well known that the sensory nerve cell bodies of spinal afferents reside within dorsal root ganglia (DRG), identifying their endings in internal organs has been especially challenging because of a lack of techniques to distinguish them from endings of other extrinsic and intrinsic neurons (sympathetic, parasympathetic and enteric)...
November 17, 2016: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/27856205/differential-expression-of-romk-and-kcnq1-potassium-channels-in-bladder-urothelium-of-patients-with-interstitial-cystitis-painful-bladder-syndrome
#18
Jane-Dar Lee, Ming-Huei Lee, Wen-Kai Yang, Kuan-Lin Wang, Tsung-Han Lee
OBJECTIVE: To investigate the changes including expression and localization of two potassium channels, renal outer medullary K(+) channel (ROMK) and voltage-gated K(+) channel 7.1 (KCNQ1), after increased urinary potassium leakage in patients with interstitial cystitis/painful bladder syndrome (IC/PBS). METHODS: The study group included 24 patients with IC/PBS and a control group consisting of 12 volunteers without any IC/PBS symptoms. Bladder biopsies were taken from both groups...
November 14, 2016: Urology
https://www.readbyqxmd.com/read/27852964/spinal-astrocytic-activation-contributes-to-mechanical-allodynia-in-a-rat-model-of-cyclophosphamide-induced-cystitis
#19
Bolong Liu, Minzhi Su, ShaoJun Tang, Xiangfu Zhou, Hailun Zhan, Fei Yang, Wenbiao Li, Tengcheng Li, Juncong Xie
BACKGROUND: Previous studies have demonstrated that glial cells play an important role in the generation and maintenance of neuropathic pain. Activated glial cells produce numerous mediators such as proinflammatory cytokines that facilitate neuronal activity and synaptic plasticity. Similarly, bladder pain syndrome/interstitial cystitis shares many characteristics of neuropathic pain. However, related report on the involvement of spinal glia in bladder pain syndrome/interstitial cystitis-associated pathological pain and the underlying mechanisms are still lacking...
2016: Molecular Pain
https://www.readbyqxmd.com/read/27847920/removal-of-foreign-bodies-embedded-in-the-urinary-bladder-wall-by-a-combination-of-laparoscopy-and-carbon-dioxide-cystoscopic-assistance-case-report-and-literature-review
#20
Chengyue Jin, Yu Fan, Qian Zhang, Yu Wang, Shiliang Wu, Jie Jin
PURPOSE: To report a case of combined laparoscopic and carbon dioxide partial cystectomy and foreign body removal and to review the existing literature on the topic. MATERIALS AND METHODS: A 43-year-old Asian woman was found to have an intrauterine device embedded in the bladder wall during evaluation for chronic pelvic pain and urinary tract infection. She underwent cystoscopic-laparoscopic partial cystectomy, with an uncomplicated postoperative course. She had normal renal function during the follow-up period...
November 2016: Investigative and Clinical Urology
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