keyword
MENU ▼
Read by QxMD icon Read
search

Bladder pain

keyword
https://www.readbyqxmd.com/read/28102552/could-urinary-nerve-growth-factor-be-a-biomarker-for-overactive-bladder%C3%A2-a-meta-analysis
#1
REVIEW
Wei Sheng, Hongwei Zhang, Kirschner-Hermanns Ruth
OBJECTIVE: The previously reported association between urinary nerve growth factor (NGF) and overactive bladder (OAB) was controversial. We performed this meta-analysis based on current available studies to sum up all evidence on this association. METHODS: Studies were identified by searching PubMed, Embase, and Cochrane library from inception to September 2016. Pooled standardized mean difference (SMD) with their corresponding 95% confidence intervals (CIs) were calculated using a random-effects model...
January 19, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28096911/depression-and-catastrophizing-predict-suicidal-ideation-in-tertiary-care-patients-with-interstitial-cystitis-bladder-pain-syndrome
#2
Dean A Tripp, J Curtis Nickel, Adrijana Krsmanovic, Michel Pontari, Robert Moldwin, Robert Mayer, Lesley K Carr, Claire C Yang, Jorgen Nordling
INTRODUCTION: We sought to evaluate psychosocial factors as predictors of suicidal ideation (SI) in a tertiary care outpatient sample of women suffering from interstitial cystitis/bladder pain syndrome (IC/BPS). METHODS: The patients are women managed at tertiary care centres (n=190). Controls were recruited from the community (n=117). Both groups completed questionnaires on demographics, pain (McGill Pain Questionnaire), IC/BPS symptoms, and psychological variables...
November 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28092830/trpv1-antagonism-by-piperazinyl-aryl-compounds-a-topomer-comfa-study-and-its-use-in-virtual-screening-for-identification-of-novel-antagonists
#3
Rajendra Kristam, Shashidhar N Rao, Anne Sudha D'Cruz, Vijayalakshmi Mahadevan, Vellarkad N Viswanadhan
Transient Receptor Potential Vanilloid, member 1 (TRPV1), is a non-selective cation channel belonging to the transient receptor potential (TRP) family of ion channels. It occurs in the peripheral and central nervous system, activated by a variety of exogenous and endogenous stimuli, thus playing a key role in transmission of pain. This has been a target for chronic pain since more than a decade and a number of antagonists that progressed into clinical trials have failed due to the unexpected side effect of core body temperature rise, thus halting progress in this field...
January 7, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28089812/clinical-manifestations-and-outcomes-in-surgically-managed-gartner-duct-cysts-1
#4
Adela G Cope, Shannon Laughlin-Tommaso, Abimbola Famuyide, John B Gebhart, Matthew R Hopkins, Daniel M Breitkopf
STUDY OBJECTIVE: Gartner duct cysts (GDC) are rare embryological remnants of the mesonephric duct with the majority of cases discovered incidentally in asymptomatic patients. The largest prior published series evaluating surgical management of GDC included 4 patients. The present study aims to determine the manifestations and outcomes of surgically managed patients with GDC with important implications for surveillance, monitoring, and management of patients. DESIGN: Retrospective chart review DESIGN: Classification: Canadian Task Force Classification III SETTING: Tertiary care center PATIENTS: All women diagnosed with GDC from 1/1994-4/2014 at our institution were identified...
January 12, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28089810/laparoscopic-management-of-ureteral-endometriosis-and-hydronephrosis-associated-with-endometriosis
#5
João Alves, Marco Puga, Rodrigo Fernandes, Anne Pinton, Ignacio Miranda, Elias Kovoor, Arnaud Wattiez
STUDY OBJECTIVES: To evaluate if laparoscopic treatment of ureteral endometriosis is feasible, safe, and effective and to determine if ureteral dilatation and/or the number of incisions increases complications. DESIGN: An institutional review board-approved retrospective cohort study of consecutive patients who underwent surgery for deep infiltrating endometriosis involving the ureter with hydronephrosis (Canadian Task Force Classification III) SETTING: University hospital PARTICIPANTS: Of 658 patients who had surgery for deep infiltrating endometriosis between November 2004 and December 2013, 198 of the 658 patients had ureteral endometriosis and required ureterolysis, and 28 of the 198 patients were identified with ureteral dilatation and hydronephrosis associated with endometriosis...
January 12, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28089079/repeated-subarachnoid-administrations-of-autologous-mesenchymal-stromal-cells-supported-in-autologous-plasma-improve-quality-of-life-in-patients-suffering-incomplete-spinal-cord-injury
#6
Jesús Vaquero, Mercedes Zurita, Miguel A Rico, Celia Bonilla, Concepción Aguayo, Cecilia Fernández, Noemí Tapiador, Marta Sevilla, Carlos Morejón, Jesús Montilla, Francisco Martínez, Esperanza Marín, Salvador Bustamante, David Vázquez, Joaquín Carballido, Alicia Rodríguez, Paula Martínez, Coral García, Mercedes Ovejero, Marta V Fernández
BACKGROUND AIMS: Cell therapy with mesenchymal stromal cells (MSCs) offers new hope for patients suffering from spinal cord injury (SCI). METHODS: Ten patients with established incomplete SCI received four subarachnoid administrations of 30 × 10(6) autologous bone marrow MSCs, supported in autologous plasma, at months 1, 4, 7 and 10 of the study, and were followed until the month 12. Urodynamic, neurophysiological and neuroimaging studies were performed at months 6 and 12, and compared with basal studies...
January 6, 2017: Cytotherapy
https://www.readbyqxmd.com/read/28087935/diagnosis-treatment-and-prevention-of-urinary-tract-infection
#7
Paula Pietrucha-Dilanchian, Thomas M Hooton
UTI may involve the lower or upper urinary tract and may be uncomplicated or complicated. The emphasis of this chapter is uncomplicated UTI. The diagnosis of uncomplicated cystitis (bladder infection) and pyelonephritis (kidney infection) is usually easily made based on the clinical presentation, whereas the diagnosis in patients with complicated UTI is often more complex. Thus uncomplicated cystitis is usually manifested by dysuria, frequency and/or urgency without fever, and pyelonephritis is usually manifested by fever and back pain/costovertebral angle tenderness...
December 2016: Microbiology Spectrum
https://www.readbyqxmd.com/read/28087925/host-responses-to-urinary-tract-infections-and-emerging-therapeutics-sensation-and-pain-within-the-urinary-tract
#8
Lori A Birder, David J Klumpp
Urinary tract infection (UTI) pathogenesis is understood increasingly at the level of the uropathogens and the cellular and molecular mediators of host inflammatory responses. However, little is known about the mediators of symptoms during UTI and what distinguishes symptomatic events from asymptomatic bacteriuria. Here, we review bladder physiology and sensory pathways in the context of an emerging literature from murine models dissecting the host and pathogen factors mediating pain responses during UTI. The bladder urothelium is considered a mediator of sensory responses and appears to play a role in UTI pain responses...
October 2016: Microbiology Spectrum
https://www.readbyqxmd.com/read/28069871/spontaneous-proximal-ureteric-rupture-secondary-to-ureterolithiasis
#9
Keith Pace, Karl Spiteri, Karl German
We present the case of a 37-year-old lady who presented with severe colicky left sided flank pain associated with vomiting, chills and rigors. A non-contrast Computed Tomography of the Kidney Ureter and Bladder was performed which showed a 2-3 mm stone in the pelvic part of the left ureter. Following 2 days of conservative treatment she was still complaining of increasingly severe pain. A contrast computed tomography of the abdomen was performed which was suggestive of a perforation of the left collecting system...
January 9, 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28065811/huge-prostatic-utricle-with-transitional-cell-carcinoma-in-an-adult
#10
Anil Kumar N, Sreeranga Y L, Tyagi A, Vijayalakshmi Devi B
A 21-year-old man with pain lower abdomen and hematuria of 10 days duration was evaluated and found to have large cystic lesion behind the urinary bladder and was confirmed to be a large prostatic utricle with solid component on contrast enhanced computed tomography (CECT), magnetic resonance imaging (MRI) and on Transrectal ultrasonography (TRUS). Post operative histopathology revealed transitional cell carcinoma.
January 5, 2017: Urology
https://www.readbyqxmd.com/read/28056917/fulranumab-in-patients-with-interstitial-cystitis-bladder-pain-syndrome-observations-from-a-randomized-double-blind-placebo-controlled-study
#11
Hao Wang, Lucille J Russell, Kathleen M Kelly, Steven Wang, John Thipphawong
BACKGROUND: This study was designed to evaluate the efficacy and safety of fulranumab, a fully human monoclonal antibody directed against nerve growth factor (NGF), for pain relief in patients with interstitial cystitis/bladder pain syndrome (IC/BPS). METHODS: In this multicenter, double-blind study, adults with IC/BPS (i.e., interstitial cystitis symptom index [ICSI] total score ≥8) accompanied by chronic, moderate-to-severe pain were randomized to fulranumab 9 mg or matching placebo, administered subcutaneously at weeks 1, 5, and 9...
January 5, 2017: BMC Urology
https://www.readbyqxmd.com/read/28050795/how-different-cystoscopy-methods-influence-patient-sexual-satisfaction-anxiety-and-depression-levels-a-randomized-prospective-trial
#12
Wojciech Krajewski, Katarzyna Kościelska-Kasprzak, Joanna Rymaszewska, Romuald Zdrojowy
PURPOSE: Bladder cancer (BC) is one of the most common cancers worldwide. BC diagnosis and surveillance is based on cystoscopy (CS). CS impact on patient's depression, anxiety, and sexual satisfaction (SS) is not sufficiently studied. There are no data on patient's comfort with flexible or rigid CS. METHODS: We prospectively evaluated pain perception (PP), depression, anxiety, and SS of 100 male patients who previously underwent at least one rigid CS in our department as surveillance after TURB procedure due to non-muscle-invasive BC and were scheduled for the next CS examination...
January 3, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28048092/su-g-iep1-10-permeability-evaluation-of-interstitial-cystitis-by-dce-mri-of-the-bladder
#13
D Wu, J Vo, J North, R Towner, R Hurst
PURPOSE: Interstitial cystitis (IC) is a chronic and painful condition that can lead to bladder pain syndrome (BPS) in women. IC and BPS have been known to manifest after physiological changes after giving birth. In this project, we pioneered and advanced a new clinical utility using DCE-MRI to assess bladder permeability. At first IC/BPS perfusion methods were with ratio signal evaluation, we now incorporate pharmacokinetics techniques to allow for further assessment. METHODS: In this pilot study, female patients and volunteers (IC=4, Control=3) underwent imaging with a clinical GE 3T 750W MRI system...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28035695/effects-of-low-energy-shock-wave-therapy-on-inflammatory-moleculars-bladder-pain-and-bladder-function-in-a-rat-cystitis-model
#14
Hung-Jen Wang, Wei-Chia Lee, Pradeep Tyagi, Chao-Cheng Huang, Yao-Chi Chuang
AIMS: Low energy shock wave (LESW) is known to facilitate tissue regeneration with analgesic and anti-inflammatory effects. We examined the effects of LESW on the expression of inflammatory molecules, pain behavior, and bladder function in a rat cystitis model. METHODS: Control and experimental animals were injected with saline or cyclophosphamide (CYP; 75 mg/kg intraperitoneally) on day 1 and 4. After lower midline incision, the bladders were exposed to LESW (300 pulses, 0...
December 30, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28032091/comparative-evaluation-of-different-volumes-of-70-alcohol-in-celiac-plexus-block-for-upper-abdominal-malignsancies
#15
Archana Dolly, Sarita Singh, Ravi Prakash, Jaishri Bogra, Anita Malik, Vinita Singh
CONTEXT: Celiac plexus block (CPB) (is an effective way to reduce cancer-associated pain in upper abdominal malignancies. AIMS: To evaluate the efficacy and safety of different volumes of 70% alcohol in CPB. SETTINGS AND DESIGN: Prospective, randomized, controlled clinical study. SUBJECTS AND METHODS: Thirty patients of carcinoma gall bladder were randomly divided into three groups (n = 10) to receive 20, 30, and 40 ml of 70% alcohol in CPB...
October 2016: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/28028822/long-term-outcomes-for-transobturator-tension-free-vaginal-tapes-in-women-with-urodynamic-mixed-urinary-incontinence
#16
Mohamed Abdel-Fattah, Gabriel Cao, Alyaa Mostafa
AIMS: To assess the long-term patient reported outcomes following transobturator tension-free vaginal tapes (TO-TVT) in women with urodynamic mixed urinary incontinence (MUI). METHODS: A secondary analysis of the 9-year follow-up of the E-TOT study: 341 women with predominant stress urinary incontinence symptoms were randomized to undergo either inside-out or outside-in TO-TVT between April 2005 and April 2007. Forty-eight women had preoperative urodynamic MUI and were available for 9-year follow-up...
December 28, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28012262/noninvasive-experimental-bladder-pain-assessment-in-painful-bladder-syndrome
#17
F F Tu, J N Kane, K M Hellman
OBJECTIVE: To compare bladder sensitivity between patients with pelvic pain and patients who were pain free, undergoing noninvasive, controlled bladder distension via diuresis. We also sought to measure potential mechanisms underlying bladder sensitivity. DESIGN: Prospective observational study. SETTING: Community teaching hospital. POPULATION: Reproductive-age women with non-bladder chronic pelvic pain (CPP, n = 23), painful bladder syndrome (PBS, n = 23), and pelvic pain-free controls (n = 42) METHODS: Participants were compared on cystometric capacity, pelvic floor pressure-pain thresholds (PPTs), pelvic muscle function, O'Leary-Sant bladder questionnaire, and psychosocial instruments using Wilcoxon rank-sum tests...
January 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28011062/factors-associated-with-pain-in-individuals-infected-by-human-t-cell-lymphotropic-virus-type-1-htlv-1
#18
Dislene N Dos Santos, Kionna O B Santos, Alaí B Paixão, Rosana Cristina P de Andrade, Davi T Costa, Daniel L S-Martin, Katia N Sá, Abrahão F Baptista
INTRODUCTION: Despite the high prevalence of chronic pain in individuals infected with HTLV-1, predictive and protective factors for its development are still unclear. OBJECTIVE: To identify factors associated with chronic pain in individuals with HTLV-1. METHODS: This cross-sectional study was conducted in a reference center for treatment of patients infected with HTLV-1 in Salvador, Bahia, Brazil. The study included individuals infected with HTLV-1, over 18 years, and excluded those with difficulty to respond the pain protocol...
December 20, 2016: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28002455/evidence-for-the-role-of-mast-cells-in-cystitis-associated-lower-urinary-tract-dysfunction-a-multidisciplinary-approach-to-the-study-of-chronic-pelvic-pain-research-network-animal-model-study
#19
Xu Wang, Wujiang Liu, Michael O'Donnell, Susan Lutgendorf, Catherine Bradley, Andrew Schrepf, Liwei Liu, Karl Kreder, Yi Luo
Bladder inflammation frequently causes cystitis pain and lower urinary tract dysfunction (LUTD) such as urinary frequency and urgency. Although mast cells have been identified to play a critical role in bladder inflammation and pain, the role of mast cells in cystitis-associated LUTD has not been demonstrated. Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic and debilitating inflammatory condition of the urinary bladder characterized by the hallmark symptoms of pelvic pain and LUTD. In this study we investigated the role of mast cells in LUTD using a transgenic autoimmune cystitis model (URO-OVA) that reproduces many clinical correlates of IC/BPS...
2016: PloS One
https://www.readbyqxmd.com/read/28001179/lupus-cystitis-presenting-with-hidronephrosis-and-gastrointestinal-involvement
#20
Flávio Teles, Larissa Gonçalves de Albuquerque Santos, Carlos Eugênio Lira Tenório, Monique Ramalho Marinho, Saulo Rodrigo de Ramalho Moraes, Davi de Brito Câmara, Renata Oliveira Santos, Camila Ricardo Uchôa Lins, André Falcão Pedrosa Costa
INTRODUCTION: Lupus cystitis is a rare manifestation of systemic lupus erythematosus, characterized by thickening of the bladder wall, associated with ureterohydronephrosis. In several cases gastrointestinal symptoms are the main manifestation. The optimal immunosuppressive regimen is still unknown. METHODS: 16-year-old girl with systemic lupus erythematosus was admitted with dysuria, renal impairment, diarrhea, abdominal pain, nausea and vomiting. An abdominal CT scan demonstrated moderate bilateral dilation from the pelvis to the ureterovesical junction, and the bladder exhibited reduced capacity and diffusely thickened walls...
December 2016: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
keyword
keyword
54752
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"