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https://www.readbyqxmd.com/read/29241263/systematic-review-of-oral-therapy-for-the-treatment-of-symptoms-of-bladder-pain-syndrome-the-brazilian-guidelines
#1
Thaís Guimarães Dos Santos, Isabela Albuquerque Severo de Miranda, Christiana Campani Nygaard, Lucas Schreiner, Rodrigo de Aquino Castro, Jorge Milhen Haddad
Interstitial cystitis (IC), including bladder pain syndrome (BPS), is a chronic and debilitating disease that mainly affects women. It is characterized by pelvic pain associated with urinary urgency, frequency, nocturia and negative urine culture, with normal cytology. In 2009, the Society for Urodynamics and Female Urology (SUFU) defined the term IC/BPS as "an unpleasant sensation (pain, pressure, and discomfort) perceived to be related to the urinary bladder, associated with lower urinary tract symptoms for more than 6 weeks duration, in the absence of infection or other identifiable causes...
December 14, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29239187/-immunotherapy-for-bladder-cancer
#2
T Büchler
Urothelial carcinoma is the most common urological malignancy. Nonspecific immunotherapy using the Bacillus Calmette-Guerin vaccine has long been the mainstay for the treatment of high-risk superficial bladder carcinoma in an adjuvant setting after transurethral endoscopic resection. In metastatic disease, cisplatin-based chemotherapy remains the main therapeutic modality. In Europe, the standard second-line chemotherapy for patients with cisplatin-refractory tumours is vinflunine. Other systemic treatments with a lower level of evidence include paclitaxel and docetaxel...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/29238222/the-burden-of-selected-cancers-in-the-us-health-behaviors-and-health-care-resource-utilization
#3
Laura Iadeluca, Jack Mardekian, Pratibha Chander, Markay Hopps, Geoffrey T Makinson
Objective: To characterize the disease burden among survivors of those cancers having the highest incidence in the US. Methods: Adult (≥18 years) survivors of the 11 most frequently diagnosed cancers were identified from publically available data sources, including the Surveillance Epidemiology and End Results 9 1973-2012, National Health Interview Survey 2013, and the Medical Expenditure Panel Survey 2011. Chi-square tests and one-way analyses of variance were utilized to assess differences between cancer survivors and non-cancer controls in behavioral characteristics, symptoms and functions, preventative screenings, and health care costs...
2017: Cancer Management and Research
https://www.readbyqxmd.com/read/29232351/randomized-clinical-trial-of-lidocaine-analgesia-for-transurethral-bladder-catheterization-delivered-via-blunt-tipped-applicator-in-young-children
#4
Neil G Uspal, Bonnie Strelitz, Jesse Gritton, Kristin Follmer, Miranda C Bradford, Taryn L Colton, Paul A Merguerian, Eileen J Klein
OBJECTIVE: Transurethral bladder catheterization (TUBC) is a painful, frequently performed procedure for collecting sterile urine. We sought to determine if administration of intraurethral lidocaine before TUBC using a blunt tipped syringe decreases procedural pain in young children in the pediatric emergency department. METHODS: Randomized clinical trial of children 0 to 36 months old requiring TUBC for collection of urine in a pediatric emergency department was performed...
December 11, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29232035/therapeutic-effects-of-endoscopic-ablation-in-hunner-type-interstitial-cystitis-patients
#5
Kwang Jin Ko, Hyunwoo Chung, Yoon Seok Suh, Sin Woo Lee, Tae Heon Kim, Kyu-Sung Lee
OBJECTIVES: To investigate the efficacy of endoscopic ablation of Hunner lesions (HLs) in patients with interstitial cystitis (IC) and to find predictors of early recurrence of HLs. MATERIALS AND METHODS: A prospective study was performed for Hunner type IC who underwent transurethral ablation. We repeated endoscopic ablation when symptoms and HLs recurred during the follow-up period. The primary endpoint was recurrence-free time. Secondary endpoints were a change of number of frequency, nocturia, and urgency episodes and changes in visual analogue scale for pain and other symptom indices at follow-up visits...
December 12, 2017: BJU International
https://www.readbyqxmd.com/read/29231514/-development-of-non-traumatic-pain-acupuncture-moxibustion-apparatus-and-its-industrialization
#6
Qian Ran, Xingpeng Jiang
In order to alleviate the discomforts induced by the invasive manipulation of acupuncture, improve the acceptability of acupuncture-moxibustion therapy and promote the application of it in healthcare, the research team developed the non-traumatic-pain acupuncture-moxibustion apparatus for disease treatment and prevention as well as healthcare, such as crude herbal moxibustion plus cupping device (cupping device), the healthcare cloth for warming the governor vessel (healthcare cloth) and the governor vessel intelligent diagnosis apparatus (diagnosis apparatus)...
June 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29229221/intravesical-electromotive-botulinum-toxin-type-a-administration-for-management-of-urinary-incontinence-secondary-to-neuropathic-detrusor-overactivity-in-children-long-term-follow-up
#7
Seyedeh-Sanam Ladi-Seyedian, Lida Sharifi-Rad, Abdol-Mohammad Kajbafzadeh
OBJECTIVES: To investigate the long-term efficacy and success rate of intravesical electromotive botulinum toxin type A (BoNTA) "Dysport®" administration in myelomeningocele (MMC) patients who had urinary incontinence due to neuropathic detrusor overactivity (NDO). METHODS: Twenty four MMC patients (mean age: 9± 3.6 years, range: 3-16) were included in the study and followed up for six years. Using an electrode bladder catheter, 10 IU/kg of Dysport® (BoNTA) was inserted into the bladder for electromotive drug administration (EMDA) without anesthesia on outpatient basis...
December 8, 2017: Urology
https://www.readbyqxmd.com/read/29225757/dengue-fever-in-a-south-asian-metropolis-a-report-on-219-cases
#8
Shiv Sekhar Chatterjee, Ankush Sharma, Shilpee Choudhury, Sushil Kumar Chumber, Ras Bage, Nittin Parkhe, Uma Khanduri
Background and Objectives: Yearly epidemics of Dengue fever occur post-monsoon in India's capital, Delhi. A prospective observational study was conducted during the outbreak months to understand the epidemiology and outcome of this infection and its economic impact. Materials and Methods: Febrile hospitalized (n=219) patients with dengue fever diagnosed by a combination of MAC-ELISA, GAC-ELISA and NS1Antigen-ELISA were enrolled. Epidemiologic (including economic) parameters, clinical, radiological and laboratory manifestations were noted and patients followed up over the period of hospital stay...
June 2017: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/29225061/crowdsourcing-disease-biomarker-discovery-research-the-ip4ic-study
#9
Michael B Chancellor, Sarah N Bartolone, Andrew Veerecke, Laura E Lamb
PURPOSE: Biomarker discovery is limited by readily assessable, cost efficient, human samples available in large numbers that represent the entire heterogeneity of the disease. We developed a novel active participation crowdsourcing method to develop a Bladder Permeability Defect Risk Score (BP-RS) based on non-invasive urinary cytokines to discriminate Interstitial cystitis/bladder pain syndrome (IC/BPS) with Hunner's lesion (UIC) patients from controls and IC patients without Hunner's lesions...
December 7, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29223727/urodynamic-characteristics-might-be-variable-in-bladder-pain-syndrome-interstitial-cystitis-patients-with-different-non-bladder-co-morbid-conditions
#10
Wei-Ming Cheng, Yu-Hua Fan, Alex T L Lin
BACKGROUND: The aim of the study was to identify the impact of non-bladder co-morbid conditions on the urodynamic characteristics of patients with bladder pain syndrome/interstitial cystitis. METHODS: Patients with bladder pain syndrome/interstitial cystitis completed the screening questionnaires for chronic fatigue syndrome, irritable bowel syndrome, fibromyalgia, temporo-mandibular disorders, multiple chemical sensitivities, tension/migraine headache, and localized myofascial pain disorder...
December 6, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29222825/outcome-of-sonography-based-minimally-invasive-surgery-for-deep-infiltrating-endometriosis-of-the-ureter-and-urinary-bladder-a-retrospective-cohort-study
#11
Gernot Hudelist, Ayman Tammaa, Kristine Aas-Eng, Lisa Kirchner, Nadja Fritzer, Zoltan Nemeth, Michael Lamche
INTRODUCTION: To evaluate the accuracy of transvaginal sonography for preoperative detection of bladder endometriosis and surgical outcomes regarding fertility and pain symptoms of women with urinary tract endometriosis. MATERIAL AND METHODS: Retrospective cohort study of consecutive patients with urinary tract endometriosis undergoing laparoscopic partial cystectomy and/or ureterolysis/decompression, ureteric resection and end-to-end anastomosis or ureteroneocystostomy for ureteral stenosis and hydronephrosis...
December 8, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29220303/locally-aggressive-connective-tissue-tumors
#12
Mrinal M Gounder, David M Thomas, William D Tap
In this review, we highlight the complexities of the natural history, biology, and clinical management of three intermediate connective tissue tumors: desmoid tumor (DT) or aggressive fibromatosis, tenosynovial giant cell tumor (TGCT) or diffuse-type pigmented villonodular synovitis (dtPVNS), and giant cell tumor of bone (GCTB). Intermediate histologies include tumors of both soft tissue and bone origin and are locally aggressive and rarely metastatic. Some common aspects to these tumors are that they can be locally infiltrative and/or impinge on critical organs, which leads to disfigurement, pain, loss of function and mobility, neurovascular compromise, and occasionally life-threatening consequences, such as mesenteric, bowel, ureteral, and/or bladder obstruction...
December 8, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29218704/sacral-neuromodulation-for-pelvic-pain-and-pelvic-organ-dysfunction-a-case-series
#13
Thierry Vancaillie, Lauren Kite, Elizabeth Howard, Jason Chow
BACKGROUND: The use of neuromodulation is growing and it is an established therapy for conditions such as bladder dysfunction. It is an increasingly used therapy for the management of chronic perineal pain but little research is currently available looking at its efficacy. AIM: We present a series of 52 patients who underwent placement of a neuromodulator, the majority of whom suffered from perineal pain, with most placements via the sacral hiatus. METHOD: Patients were asked to complete a survey recalling their symptoms prior to implantation and describing their symptoms and experience after...
December 8, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29212771/establishment-of-a-surgical-bile-duct-injection-technique-giving-direct-access-to-the-bile-ducts-for-studies-of-the-murine-biliary-tree
#14
Natalie Lie Berntsen, Bjarte Fosby, Laura Valestrand, Corey Tan, Henrik Reims, Elisabeth Schrumpf, Tom H Karlsen, Pål-Dag Line, Espen Melum
Cholangiopathies are progressive disorders with largely unknown pathoetiology and limited treatment options. We aimed to develop a novel surgical technique with direct access to the bile ducts that would complement existing mouse models of cholestasis, biliary inflammation and fibrosis, and present a new route of administration for testing of potential treatment strategies. We developed a surgical technique to access the murine biliary tree by injection of different solvents through catheterization of the gall bladder with simultaneous clamping of the common bile duct...
December 6, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29211040/promoting-long-term-health-among-people-with-spinal-cord-injury-what-s-new
#15
Mary Ann McColl, Shikha Gupta, Karen Smith, Alexander McColl
A key ingredient to successful health promotion is a primary care provider who can offer an informed first response to lifestyle issues, emerging problems and chronic challenges. This article aims to assist family physicians to play their role in promoting the health of people with SCI, by summarizing the latest evidence in the management of spinal cord injury in primary care. This study used a scoping review methodology to survey peer-reviewed journal articles and clinical guidelines published between January 2012 to June 2016...
December 6, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29209615/simultaneous-hepatic-and-mesenteric-hydatid-disease-a-case-report
#16
Daniel Paramythiotis, Anestis Karakatsanis, Petros Bangeas, Konstantinia Kofina, Vassileios Papadopoulos, Stylianos Apostolidis, Antonios Michalopoulos
Introduction: Hydatid cysts most commonly present in the liver and the lungs; however, they can appear more rarely in other locations, such as the mesentery, with a rather unclear mechanism of manifestation. Herein, we present a case of simultaneous presence of hydatid cysts in the liver and the mesentery of a young man. Case report: A 39-year-old man was referred to our Department for further investigation of intermittent abdominal pain, especially in the right upper quadrant, and abdominal distension...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/29207771/aspects-of-evolving-genito-urinary-tuberculosis-a-profile-of-genito-urinary-tuberculosis-gutb-in-110-patients
#17
Sriram Krishnamoorthy, Velmurugan Palaniyandi, Natarajan Kumaresan, Sivasankar Govindaraju, Jayaganesh Rajasekaran, Ilangovan Murugappan, Venkat Ramanan, Muthulatha Navaneetha Krishnan
Introduction: Genito Urinary Tuberculosis (GUTB) is a widespread disease seen in urology practice. The true incidence and prevalence of GUTB is difficult to estimate because a large number of patients remain asymptomatic. Aim: To recognize typical and atypical clinical and radiological features of tuberculosis and to emphasize the need for diagnosing GUTB early. Materials and Methods: This was a retrospective study conducted in 110 cases of GUTB diagnosed and treated in two teaching institutions over a period of three years, from July 2002 to June 2005...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29203988/correlation-of-transabdominal-ultrasonography-and-cystoscopy-in-follow-up-of-patients-with-non-muscle-invasive-bladder-cancer
#18
Ahluwalia Puneet, Nair Balagopal, Kumar Ginil, Mathew Georgie, K V Sanjeevan, Thomas Appu
Cystoscopy (CS) is considered to be the gold standard in the follow-up of non-muscle invasive bladder cancer. However, CS is invasive, time-consuming, and expensive. On the other hand, modern sensitive transducers have improved the imaging of urinary tract rendering transabdominal ultrasonography (US) more effective in visualizing intraluminal filling defects in the bladder than it was in the past. Twenty-five follow-up patients of low-risk bladder cancer meeting the inclusion and exclusion criteria were included in study...
December 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29198921/research-progress-of-capsaicin-responses-to-various-pharmacological-challenges
#19
REVIEW
Pompy Patowary, Manash Pratim Pathak, Kamaruz Zaman, P S Raju, Pronobesh Chattopadhyay
Capsaicin, a well known vanilloid, has shown evidence of an ample variety of biological effects which make it the target of extensive research ever since its identification. In spite of the fact that capsaicin causes health hazards in quite a few ways, yet, the verity cannot be ignored that capsaicin has several therapeutic implications. In patients with hypersensitive bladders, vesical instillation of 1 mM capsaicin markedly improved urinary frequency and urge incontinence. Again, administration of capsaicin favors an augmentation in lipid mobilization and a decrease in adipose tissue mass...
November 29, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29194531/conservative-surgery-versus-colorectal-resection-in-deep-endometriosis-infiltrating-the-rectum-a-randomized-trial
#20
Horace Roman, Michael Bubenheim, Emmanuel Huet, Valérie Bridoux, Chrysoula Zacharopoulou, Emile Daraï, Pierre Collinet, Jean-Jacques Tuech
STUDY QUESTION: Is there a difference in functional outcome between conservative versus radical rectal surgery in patients with large deep endometriosis infiltrating the rectum 2 years postoperatively? SUMMARY ANSWER: No evidence was found that functional outcomes differed when conservative surgery was compared to radical rectal surgery for deeply invasive endometriosis involving the bowel. WHAT IS KNOWN ALREADY: Adopting a conservative approach to the surgical management of deep endometriosis infiltrating the rectum, by employing shaving or disc excision, appears to yield improved digestive functional outcomes...
November 29, 2017: Human Reproduction
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