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https://www.readbyqxmd.com/read/29471601/-bladder-rupture-during-intravesical-bcg-therapy-a-case-report
#1
Yusuke Iemura, Shinji Fukui, Yoshiaki Matsumura, Yoriaki Kagebayashi, Yuta Toyoshima, Takeshi Inoue, Shoji Samma
A 69-year-old man received transurethral resection (TUR) ofbladder tumor. The histopathological diagnosis was urothelial carcinoma, high grade, pT1+pTis. The surgical specimens obtained by second TUR showed no residual malignancy histopathologically. Intravesical Bacillus Calmette-Guerin (BCG) instillation therapy was initiated 2 months after the second TUR. He complained of lower abdominal pain and painful urination on the day following the second instillation of BCG. Computed tomography and cystography demonstrated rupture ofthe urinary bladder...
January 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29465304/a-mapp-network-study-overexpression-of-tumor-necrosis-factor-%C3%AE-in-mouse-urothelium-mimics-interstitial-cystitis
#2
Wenbin Yang, Timothy J Searl, Ryan E Yaggie, Anthony J Schaeffer, David J Klumpp
Interstitial cystitis/ bladder pain syndrome (IC/BPS) is a chronic bladder condition associated with pain and voiding dysfunction that is often regarded as a neurogenic cystitis. Patient symptoms are correlated with the presence of urothelial lesions. We previously characterized a murine neurogenic cystitis model that recapitulates mast cell accumulation and urothelial lesions, and these events were dependent upon TNF. To further explore the role of TNF in bladder inflammation and function, we generated a transgenic mouse model with chronic TNF overexpression in urothelium under the control of the uroplakin II (UPII) promoter...
February 21, 2018: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/29464752/voluntary-wheel-running-attenuates-urinary-bladder-hypersensitivity-and-dysfunction-following-neonatal-maternal-separation-in-female-mice
#3
Angela N Pierce, Olivia C Eller-Smith, Julie A Christianson
AIMS: Patients with interstitial cystitis/painful bladder syndrome (IC/PBS) commonly suffer from widespread pain and mood disorder, which has been attributed to improper functioning of the hypothalamic-pituitary-adrenal (HPA) axis. Voluntary exercise has been shown to improve HPA axis function, therefore we are determining whether voluntary wheel running can attenuate urological pain and dysfunction following neonatal maternal separation (NMS) in female mice. METHODS: Mice underwent NMS for 3 h/day from postnatal Day 1-21, were caged with free access to running wheels at 4 weeks of age, and assessed 4 weeks later for bladder sensitivity, micturition, reward behavior, mast cell degranulation, and HPA axis-related in vitro analysis...
February 21, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29463969/sexual-dysfunction-in-interstitial-cystitis
#4
REVIEW
Senol Tonyali, Mehmet Yilmaz
Background/Aims: Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a debilitating disease characterized with urgency, frequency, and pelvic pain affecting especially women. Sexual dysfunction in female patients with IC/BPS consists of dyspareunia, altered sexual desire and orgasm frequency and insufficient lubrication is reported to negatively affect the patient's quality of life. In the present study, we aimed to determine the association between IC/BPS and sexual dysfunction and improvement in sexual dysfunction related to given treatments...
November 2017: Current Urology
https://www.readbyqxmd.com/read/29455410/can-patients-with-symptomatic-tarlov-cysts-be-differentiated-from-patients-with-specific-low-back-pain-based-on-comprehensive-history-taking
#5
Maria Anna Hulens, Wim Dankaerts, Ricky Rasschaert, Frans Bruyninckx, Marie-Laure Willaert, Charlotte Vereecke, Greet Vansant
BACKGROUND: Tarlov cysts (TCs) are expanded nerve root sheaths that occur near the dorsal root ganglion and result from increased intraspinal hydrostatic pressure. TCs most frequently affect the lumbosacral plexus and therefore may cause specific symptoms such as perineal pain and neurogenic bladder, bowel, and sphincter problems. It has been estimated that 1% of the population has symptomatic Tarlov cysts (STCs). However, STCs appear to be underdiagnosed, with the pain reported by patients commonly attributed to degenerative alterations seen on MRI...
February 17, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29452126/fda-brudac-2018-criteria-for-interstitial-cystitis-bladder-pain-syndrome-clinical-trials-future-direction-for-ic-bps-research
#6
EDITORIAL
J Curtis Nickel, Robert Moldwin
No abstract text is available yet for this article.
February 13, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29444547/laparoscopic-surgery-with-urinary-tract-reconstruction-and-bowel-endometriosis-resection-for-deep-infiltrating-endometriosis
#7
REVIEW
Yoshiaki Ota, Masaaki Andou, Ikuko Ota
Deep infiltrating endometriosis (DIE) is the most severe form of endometriosis. It causes chronic pelvic pain, severe dysmenorrhea, deep dyspareunia, dyschezia, and dysuria, markedly impairing the quality of life of women of reproductive age. A number of randomized controlled trials on surgical and medical treatments to reduce the pain associated with endometriosis have been reported, but few have focused on this in DIE. DIE causes not only pain but also functional invasion to the urinary organs and bowel, such as hydronephrosis and bowel stenosis...
February 14, 2018: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29442178/the-use-of-cannabis-and-cannabinoids-in-treating-symptoms-of-multiple-sclerosis-a-systematic-review-of-reviews
#8
REVIEW
Suzanne Nielsen, Rada Germanos, Megan Weier, John Pollard, Louisa Degenhardt, Wayne Hall, Nicholas Buckley, Michael Farrell
PURPOSE OF REVIEW: Pharmaceutical cannabinoids such as nabiximols, nabilone and dronabinol, and plant-based cannabinoids have been investigated for their therapeutic potential in treating multiple sclerosis (MS) symptoms. This review of reviews aimed to synthesise findings from high quality systematic reviews that examined the safety and effectiveness of cannabinoids in multiple sclerosis. We examined the outcomes of disability and disability progression, pain, spasticity, bladder function, tremor/ataxia, quality of life and adverse effects...
February 13, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29441652/bladder-pain-syndrome-interstitial-cystitis-is-associated-with-asthma-a-case-control-study
#9
Shiu-Dong Chung, Chung-Chien Huang, Herng-Ching Lin, Li-Ting Kao
OBJECTIVE: Although asthma and bladder pain syndrome/interstitial cystitis (BPS/IC) are considered to share similar pathophysiological pathways, the relationship between asthma and BPS/IC is uncertain. This case-control study aimed to investigate the relationship between prior asthma and BPS/IC using a large database in Taiwan. MATERIALS AND METHODS: This study used data from the Taiwan Longitudinal Health Insurance Database 2005. We identified 500 female patients with BPS/IC as cases and 500 propensity score-matched females without BPS/IC as controls...
February 14, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29441609/histopathological-characteristics-of-ketamine-associated-uropathy-and-their-clinical-association
#10
Jia-Fong Jhang, Yung-Hsiang Hsu, Yuan-Hong Jiang, Cheng-Ling Lee, Hann-Chorng Kuo
AIM: To investigate the histopathological findings in ketamine-associated uropathy (KU) and their clinical association. METHODS: Thirty-eight KU patients had received history investigation and video urodynamic study. Twelve of them were clinically mild KU who were admitted for cystoscopic hydrodistention. The other 26 patients were severe KU who were admitted for enterocystoplasty with or without ureter reimplantation. Bladder and ureter specimens were harvested during operation, and a single pathologist reviewed all specimens under hematoxylin and eosin stain...
February 14, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29439906/dermoid-cysts-of-the-conus-medullaris-clinical-review-case-series-and-management-strategies
#11
Salah G Aoun, Mary Ashley Liu, Megan Still, Tarek Y El Ahmadieh, Mazin Al Tamimi, Wayne Gluf
BACKGROUND: The management of dermoid cysts can be tedious as they have a tendency to recur, and respond poorly to chemotherapy and radiation. Management is especially difficult for tumors involving highly eloquent areas such as the conus medullaris. OBJECTIVE: We aim to provide a summary of the pathology, clinical presentation, and operative management strategies of dermoid cysts involving the conus medullaris. METHODS: Two clinical cases of dermoid cysts of the conus are presented, as well as a commented surgical video...
February 10, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29434541/the-influence-of-early-life-experience-on-visceral-pain
#12
REVIEW
Isabella M Fuentes, Julie A Christianson
Pain is the most reported and troublesome symptom of nearly all functional disorders affecting the genitourinary and gastrointestinal organs. Patients with irritable bowel syndrome (IBS), interstitial cystitis/painful bladder syndrome (IC/PBS), vulvodynia, and/or chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS; collectively termed chronic pelvic pain syndromes) report pain severe enough to impact quality of life and often suffer from symptoms of or are diagnosed with more than one of these syndromes...
2018: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/29434183/plasmacytoid-urothelial-carcinoma-of-ureter-with-retroperitoneal-metastasis-a-case-report
#13
Alexis Jibril, Andrew C Stevens
BACKGROUND Plasmacytoid is a rare histological variant of urothelial carcinoma (UC). Since the first reported case of plasmacytoid urothelial carcinoma (PUC), in 1991, only about 100 cases have since been reported, with most cases involving the bladder. Urothelial carcinomas of the upper urinary tract represent only 5% of urothelial cancers. To the best of our knowledge, there has only been 1 reported case of PUC of the ureter. PUC is a highly aggressive disease, with a poor prognosis. We present a rare biopsy-proven case of PUC of the ureter with retroperitoneal metastasis...
February 13, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29429775/effect-of-retension-sutures-on-abdominal-pressure-after-abdominal-surgery
#14
Hao Tang, Dong Liu, Hai-Feng Qi, Ze-Ping Liang, Xiu-Zhu Zhang, Dong-Po Jiang, Lian-Yang Zhang
PURPOSE: To evaluate the effect of retention sutures on abdominal pressure and postoperative prognosis in abdominal surgery patients. METHODS: This prospective cohort study included patients who were admitted to Daping Hospital from May 15, 2014 to October 11, 2014. A total of 57 patients were enrolled, including 18 patients in the "U" type retention suture group, 17 patients in the intermittent retention suture group, and 22 patients in non-retention suture group...
January 31, 2018: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/29425323/long-term-effectiveness-of-gross-total-resection-for-symptomatic-spinal-cord-cavernous-malformations
#15
Tej D Azad, Anand Veeravagu, Amy Li, Michael Zhang, Venkatesh Madhugiri, Gary K Steinberg
BACKGROUND: Intramedullary spinal cord cavernous malformations (CMs) account for 5% of all CMs in the central nervous system and 5% to 12% of all spinal cord vascular lesions, yet their optimal management is controversial. OBJECTIVE: To identify factors associated with the clinical progression of spinal cord CMs and quantify the range of surgical outcomes. METHODS: Retrospective observational cohort study of 32 patients who underwent open surgical resection for spinal CMs, the majority of which presented to a dorsal or lateral pial surface, from 1996 to 2017 at a single institution...
February 6, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29424675/intradural-spinal-arachnoid-cyst-resection-implications-of-duraplasty-in-a-large-case-series
#16
Ziev B Moses, Gabriel N Friedman, David L Penn, Isaac H Solomon, John H Chi
OBJECTIVE Optimal diagnosis and management strategies for intradural spinal arachnoid cysts (SACs) are still unresolved given the rare nature of this entity, with few large case series and virtually no statistical analyses of patient characteristics in the literature. Here, the authors studied a large patient cohort with these lesions to determine whether pre- or postoperative attributes could be used to aid in either diagnosis or prognosis. METHODS A chart review was completed at a single institution for the period from 2002 to 2016 to determine the preoperative characteristics and postoperative outcomes of 21 patients with exclusively intradural SACs...
February 9, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29424302/the-role-of-5-ht1a-receptor-in-the-cancer-as-a-new-opportunity-in-medicinal-chemistry
#17
Angela Corvino, Ferdinando Fiorino, Beatrice Severino, Irene Saccone, Francesco Frecentese, Elisa Perissutti, Paola Di Vaio, Vincenzo Santagada, Giuseppe Caliendo, Elisa Magli
The 5-HT1A receptor is a pharmacologically well characterized serotonin receptor subtype and it has long been investigated because of its involvement in several physio-pathological mechanisms and treatment of neurological diseases like ansia and depression. Serotonin (5-HT) also shows many non-neural functions such as essential hypertension, embryogenesis, follicle maturation and behavior. Moreover it exerts a growth factor function on different types of non-tumoral cells, and it was also found to be related to oncogenes...
February 9, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29423150/sub-capsular-effusion-of-liver-as-a-rare-complication-of-ventriculoperitoneal-shunt-in-a-child
#18
Ruiping Zhang, Jungang Liu, Yizheng Wang, Lirong Cao, Chunquan Cai
The most common procedure to deal with hydrocephalus is ventriculoperitoneal (VP) shunt. The purpose of the shunt is to drain cerebrospinal fluid from cerebral ventricles to abdominal cavity. Many complications of VP shunts have been reported such as infection, obstruction, overdrainage. Abdominal complications occur in ~15-25% of VP shunts in pediatric patients, such as peritonitis, hernia, abscess, perforated colon, perforated bladder and abdominal pseudocyst. However, sub-capsular effusion of liver is a rare complication of VP shunt...
October 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29422357/outpatient-holmium-laser-fulguration-a-safe-procedure-for-treatment-of-recurrence-of-nonmuscle-invasive-bladder-cancer
#19
Á Rivero Guerra, T Fernández Aparicio, I Barceló Bayonas, A Pardo Martínez, V Muñoz Guillermo, D Jiménez Peralta, C Carrillo George, B N Pietricica, E Izquierdo Morejón, A Rosino Sánchez, A Romero Hoyuela, G Hita Villaplana
BACKGROUND AND OBJECTIVE: Nonmuscle invasive bladder cancer has a high recurrence rate and a low progression rate. The aim of this study was to assess the effectiveness, safety and feasibility of Holmium laser fulguration in an outpatient regimen for selected tumours. MATERIAL AND METHOD: A prospective, longitudinal cohort study was conducted between January 2009 and December 2016. Seventy-nine Holmium laser fulguration procedures with subsequent instillation of mitomycin C were performed in an outpatient regimen on 59 patients with a history of low-risk bladder cancer and recurrence of small papillary tumours...
February 5, 2018: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/29420363/a-novel-method-to-facilitate-uterine-delivery-at-robotic-hysterectomy
#20
Shih-Ern Yao, Tom Manolitsas
Minimally invasive platforms have afforded women undergoing hysterectomy the advantages of improved postoperative pain control, reduced complication rates, and shorter inpatient recovery time. In patients where malignancy has been confirmed or suspected, the necessity for uterine delivery per vagina is imperative to maintain these advantages without compromising oncological outcome.A previously unreported technique of enlarging the apical circumference of the vagina during robotic hysterectomy facilitates intact uterine passage after extended reflection of the bladder and/or rectum...
February 8, 2018: International Journal of Gynecological Cancer
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