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https://www.readbyqxmd.com/read/29793121/head-coaches-attitudes-towards-injury-prevention-and-use-of-related-methods-in-professional-basketball-a-survey
#1
J Wilke, D Niederer, L Vogt, W Banzer
OBJECTIVES: To investigate the practices and attitudes of professional basketball head coaches towards injury prevention. DESIGN: Survey. SETTING: Elite-level basketball. PARTICIPANTS: Head coaches of all 366 German professional teams. MAIN OUTCOME MEASURES: Use of injury risk screening methods, rated importance of different musculoskeletal injuries and rated effectiveness of preventive interventions...
April 17, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29792848/subthalamic-nucleus-deep-brain-stimulation-protects-neurons-by-activating-autophagy-via-pp2a-inactivation-in-a-rat-model-of-parkinson-s-disease
#2
Ting-Ting Du, Ying-Chuan Chen, Yong-Quan Lu, Fan-Gang Meng, Hui Yang, Jian-Guo Zhang
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapeutic strategy for alleviating disability in patients with moderate to severe Parkinson's disease (PD). Preclinical studies have shown that stimulation of the rat STN can protect against nigral dopaminergic neuron loss. However, the underlying mechanism is unclear. To investigate the molecular basis of the neuroprotective effects of STN stimulation, a rat model of PD was established by unilaterally injecting 6-hydroxydopamine (6-OHDA) into the striatum...
May 21, 2018: Experimental Neurology
https://www.readbyqxmd.com/read/29792440/looking-at-the-eyes-interferes-with-facial-emotion-recognition-in-alexithymia
#3
Esther Fujiwara
Alexithymia refers to difficulties in identifying, differentiating, and describing feelings. This personality trait is highly prevalent in many psychiatric conditions and may drive associated social-emotional problems, including the ability to decode emotions in faces. This study probed alexithymic problems with identifying clear and ambiguous blends of emotions in faces and their underlying visual attention patterns. Using the Toronto Alexithymia Scale-20, students with high alexithymia (HA, n = 73) or low alexithymia (LA, n = 76) were enrolled in this study...
May 24, 2018: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/29790977/alpha-synuclein-aggregates-in-labial-salivary-glands-of-idiopathic-rapid-eye-movement-sleep-behavior-disorder
#4
Alx Iranzo, Sergi Borrego, Isabel Vilaseca, Carles Martí, Mónica Serradell, Raquel Sánchez-Valle, Gabor G Kovacs, Francesc Valldeoriola, Carles Gaig, Joan Santamaria, Eduard Tolosa, Ellen Gelpi
Study Objectives : To assess whether biopsy of the labial minor salivary glands safely detects phosphorylated alpha-synuclein (pAS) deposits in idiopathic REM sleep behavior disorder (IRBD), a condition that precedes the cardinal manifestations of synuclein disorders associated with Lewy type pathology, namely Parkinson disease (PD) and dementia with Lewy bodies (DLB). Methods: In a prospective study, labial biopsy of the minor salivary glands was performed in 62 IRBD patients, 13 PD and 10 DLB patients who were initially diagnosed with IRBD, and in 33 controls...
May 22, 2018: Sleep
https://www.readbyqxmd.com/read/29790422/autologous-induced-pluripotent-stem-cell-derived-neurons-to-treat-parkinson-s-disease
#5
Jeanne F Loring
In 2012, we planned a program to develop a neuron replacement therapy for Parkinson's disease (PD) that would have the greatest promise to help the patients. PD is a movement disorder caused by the progressive, inevitable loss of a specific type of dopamine neuron in the brain. The only viable treatment to reverse the progress of the disease is to replace those neurons; we decided to make dopamine neurons that matched the patients, by differentiating induced pluripotent stem cells (iPSCs) that we generated from individuals with PD...
May 23, 2018: Stem Cells and Development
https://www.readbyqxmd.com/read/29789954/genetics-of-movement-disorders-and-the-practicing-clinician-who-and-what-to-test-for
#6
REVIEW
Alessio Di Fonzo, Edoardo Monfrini, Roberto Erro
PURPOSE OF REVIEW: This review aims to provide the basic knowledge on the genetics of hypokinetic and hyperkinetic movement disorders to guide clinicians in the decision of "who and what to test for?" RECENT FINDINGS: In recent years, the identification of various genetic causes of hypokinetic and hyperkinetic movement disorders has had a great impact on a better definition of different clinical syndromes. Indeed, the advent of next-generation sequencing (NGS) techniques has provided an impressive step forward in the easy identification of genetic forms...
May 23, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29789897/-pilot-study-to-investigate-sleep-disorders-in-the-blind-and-persons-with-relevant-visual-impairment
#7
C Dirks, D Grünewald, P Young, A Heidbreder
BACKGROUND: Sleep disorders are associated with serious health problems in blind and visually impaired persons. Loss of light perception may result in a shift of sleep-wake pattern, which may lead to significant impairments in daily life--the so-called non-24-hour sleep-wake disorder. To date, epidemiologic data on non-24 only exist for the USA. This pilot study was conducted to provide first epidemiologic data for the prevalence of non-24 and other sleep disorders among blind and visually impaired persons in Germany...
May 22, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29789033/the-neurological-examination-adapted-for-neuropsychiatry
#8
Sheldon Benjamin, Margo D Lauterbach
The neuropsychiatric examination includes standard neurological and cognitive examination techniques with several additional observations and tasks designed to capture abnormalities common among patients with neuropsychiatric disorders or neurocognitive complaints. Although useful as a screening tool, a single standardized rating scale such as the Mini Mental State Examination (MMSE) or the Montreal Cognitive Assessment (MoCA) is insufficient to establish a neuropsychiatric diagnosis. Extra attention is paid to findings commonly seen in the setting of psychiatric disorders, dementias, movement disorders, or dysfunction of cortical or subcortical structures...
May 23, 2018: CNS Spectrums
https://www.readbyqxmd.com/read/29788710/hemiballismus-in-uncontrolled-diabetes-mellitus
#9
Juhaida Jaafar, Razlina Abdul Rahman, Nani Draman, Nor Akma Yunus
Hemiballismus, a subtype of chorea, is a rare movement disorder, and is most commonly found secondary to stroke. Movements are involuntary, violent, coarse, and have a wide amplitude. There is increasing report of hemiballismus occurring in non-ketotic hyperglycemia. Spontaneous improvements or remissions were observed in many patients, and treatment should be directed towards the cause of hemiballismus. There is no randomized control trial to guide clinicians in deciding the best treatment option when managing hemiballismus...
May 2018: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/29787868/individualized-tractography-based-parcellation-of-the-globus-pallidus-pars-interna-using-7t-mri-in-movement-disorder-patients-prior-to-dbs-surgery
#10
Rémi Patriat, Scott E Cooper, Yuval Duchin, Jacob Niederer, Christophe Lenglet, Joshua Aman, Michael C Park, Jerrold Vitek, Noam Harel
The success of deep brain stimulation (DBS) surgeries for the treatment of movement disorders relies on the accurate placement of an electrode within the motor portion of subcortical brain targets. However, the high number of electrodes requiring relocation indicates that today's methods do not ensure sufficient accuracy for all patients. Here, with the goal of aiding DBS targeting, we use 7 T (T) MRI data to identify the functional territories and parcellate the globus pallidus interna (GPi) into motor, associative and limbic regions in individual subjects...
May 19, 2018: NeuroImage
https://www.readbyqxmd.com/read/29786895/deep-brain-stimulation-treated-dystonia-trajectory-via-status-dystonicus
#11
Elodie Nerrant, Victoria Gonzalez, Christophe Milesi, Xavier Vasques, Diane Ruge, Thomas Roujeau, Isabel De Antonio Rubio, Fabienne Cyprien, Emilie Chan Seng, Diane Demailly, Agathe Roubertie, Alain Boularan, Fréderic Greco, Pierre-François Perrigault, Gilles Cambonie, Philippe Coubes, Laura Cif
BACKGROUND: Status dystonicus (SD) is a life-threatening condition. OBJECTIVE AND METHODS: In a dystonia cohort who developed status dystonicus, we analyzed demographics, background dystonia phenomenology and complexity, trajectory previous to-, via status dystonicus episodes, and evolution following them. RESULTS: Over 20 years, 40 of 328 dystonia patients who were receiving DBS developed 58 status dystonicus episodes. Dystonia was of pediatric onset (95%), frequently complex, and had additional cognitive and pyramidal impairment (62%) and MRI alterations (82...
May 22, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29785152/association-of-midline-discrepancy-with-tempromandibular-joint-disorder-a-systematic-review
#12
REVIEW
Sandhya Jain, Neetu Sharma, Pallav Patni, Deshraj Jain
Aim: The aim is to evaluate the association between midline discrepancies and tempromandibular disorders (TMDs). Methods: Literature search was performed by using various search engines to include human studies in English. TMDs include a wide variety of signs and symptoms such as pain in and around TMJ, jaw muscles, clicking and locking of jaws, pain during mandibular movement and restricted mandibular movements. The etiology is multifactorial, including one or several of the following factors like severe malocclusions (increased overjet, retroclination of incisors, cross bite, CR CO discrepancies etc), stress and psychological factors, structural abnormalities as possible etiology...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29784217/finding-inspiration-from-the-philosophy-of-maurice-merleau-ponty-for-the-practice-of-psychiatric-mental-health-nursing
#13
Sandra P Thomas
The philosophy of Maurice Merleau-Ponty, a unique blend of existentialism and phenomenology, deserves to be better known in psychiatric-mental health nursing. This philosophy is particularly pertinent to the contemporary recovery movement that seeks to dispel the therapeutic nihilism regarding conditions such as schizophrenia, borderline personality, and substance use disorders. This paper provides an overview of Merleau-Ponty's life and work, with emphasis on selected elements of his philosophy that are inspirational for the clinical practice of psychiatric-mental health nursing...
June 2018: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/29783067/motor-retraining-more-for-functional-movement-disorders-outcomes-from-a-one-week-multidisciplinary-rehabilitation-program
#14
Alexandra Jacob, Darryl Kaelin, Abbey Roach, Craig Ziegler, Kathrin LaFaver
BACKGROUND: Functional Movement Disorders (FMD) are conditions of abnormal motor control thought to be caused by psychological factors. These disorders are commonly seen in neurological practice and prognosis is often poor. No consensus treatment guidelines have been established, however the role of physical therapy in addition to psychotherapy has increasingly been recognized. This study reports patient outcomes from a multidisciplinary FMD treatment program using motor retraining (MoRe) strategies...
May 18, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29782883/a-new-outlook-on-cholinergic-interneurons-in-parkinson-s-disease-and-l-dopa-induced-dyskinesia
#15
REVIEW
Melissa M Conti, Nicole Chambers, Christopher Bishop
Traditionally, dopamine (DA) and acetylcholine (ACh) striatal systems were considered antagonistic and imbalances or aberrant signaling between these neurotransmitter systems could be detrimental to basal ganglia activity and pursuant motor function, such as in Parkinson's disease (PD) and L-DOPA-induced dyskinesia (LID). Herein, we discuss the involvement of cholinergic interneurons (ChIs) in striatally-mediated movement in a healthy, parkinsonian, and dyskinetic state. ChIs integrate numerous neurotransmitter signals using intrinsic glutamate, serotonin, and DA receptors and convey the appropriate transmission onto nearby muscarinic and nicotinic ACh receptors to produce movement...
May 18, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29781731/neuropsychologists-as-primary-care-providers-of-cognitive-health-a-novel-comprehensive-cognitive-wellness-service-delivery-model
#16
Patricia A Pimental, John B O'Hara, Jessica L Jandak
By virtue of their extensive knowledge base and specialized training in brain-behavior relationships, neuropsychologists are especially poised to execute a unique broad-based approach to overall cognitive wellness and should be viewed as primary care providers of cognitive health. This article will describe a novel comprehensive cognitive wellness service delivery model including cognitive health, anti-aging, lifelong wellness, and longevity-oriented practices. These practice areas include brain-based cognitive wellness, emotional and spiritually centric exploration, and related multimodality health interventions...
July 2018: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/29781133/inhibition-is-impaired-in-children-with-obsessive-compulsive-symptoms-but-not-in-those-with-tics
#17
Christian Mancini, Francesco Cardona, Valentina Baglioni, Sara Panunzi, Patrizia Pantano, Antonio Suppa, Giovanni Mirabella
BACKGROUND: Impaired inhibitory control is thought to be a core deficit in psychiatric disorders where patients exhibit problems with controlling urges. These problems include the urge to perform movements typical of Tourette syndrome and the urge to execute compulsive actions typical of obsessive-compulsive disorder. However, the picture emerging from studies that address this issue is controversial. Furthermore, most studies have only focused on reactive control (the ability of subjects to react to a stop signal), but not on proactive control (the ability of patients to shape their response strategies in anticipation of known task demands)...
May 21, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29780852/parkinson-s-patients-with-dyskinesia-switched-from-immediate-release-amantadine-to-open-label-ads-5102
#18
Stuart H Isaacson, Stanley Fahn, Rajesh Pahwa, Caroline M Tanner, Alberto J Espay, Claudia Trenkwalder, Charles H Adler, Rajiv Patni, Reed Johnson
Background: ADS-5102 (amantadine) extended release capsules (GOCOVRI™) are a treatment for dyskinesia in patients with Parkinson's disease (PD). ADS-5102 reduced dyskinesia and OFF time in phase 3 controlled trials of up to six months. Amantadine immediate release (IR) is used for dyskinesia, but suboptimal durability and tolerability limit its clinical utility. Methods: In an ongoing, open-label, phase 3 study in the US and Western Europe (NCT02202551), patients with PD received 274 mg of ADS-5102 (equivalent to 340 mg amantadine HCl) once daily at bedtime for up to two years...
March 2018: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/29780335/leg-movement-activity-during-sleep-in-adults-with-attention-deficit-hyperactivity-disorder
#19
Corrado Garbazza, Cornelia Sauter, Juliane Paul, Jenny Kollek, Catharine Dujardin, Sandra Hackethal, Hans Dorn, Anita Peter, Marie-Luise Hansen, Mauro Manconi, Raffaele Ferri, Heidi Danker-Hopfe
Objectives: To conduct a first detailed analysis of the pattern of leg movement (LM) activity during sleep in adult subjects with Attention-Deficit/Hyperactivity Disorder (ADHD) compared to healthy controls. Methods: Fifteen ADHD patients and 18 control subjects underwent an in-lab polysomnographic sleep study. The periodic character of LMs was evaluated with established markers of "periodicity," i.e., the periodicity index, intermovement intervals, and time distribution of LM during sleep, in addition to standard parameters such as the periodic leg movement during sleep index (PLMSI) and the periodic leg movement during sleep arousal index (PLMSAI)...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29780303/closed-loop-deep-brain-stimulation-for-ptsd-addiction-and-disorders-of-affective-facial-interpretation-review-and-discussion-of-potential-biomarkers-and-stimulation-paradigms
#20
REVIEW
Robert W Bina, Jean-Phillipe Langevin
The treatment of psychiatric diseases with Deep Brain Stimulation (DBS) is becoming more of a reality as studies proliferate the indications and targets for therapies. Opinions on the initial failures of DBS trials for some psychiatric diseases point to a certain lack of finesse in using an Open Loop DBS (OLDBS) system in these dynamic, cyclical pathologies. OLDBS delivers monomorphic input into dysfunctional brain circuits with modulation of that input via human interface at discrete time points with no interim modulation or adaptation to the changing circuit dynamics...
2018: Frontiers in Neuroscience
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