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development dysplasia of the hip

Jung Min Ko, Jae So Cho, Yongjin Yoo, Jieun Seo, Murim Choi, Jong-Hee Chae, Hye-Ran Lee, Tae-Joon Cho
Wiedemann-Steiner syndrome is a rare genetic disorder characterized by short stature, hairy elbows, facial dysmorphism, and developmental delay. It can also be accompanied by musculoskeletal anomalies such as muscular hypotonia and small hands and feet. Mutations in the KMT2A gene have only recently been identified as the cause of Wiedemann-Steiner syndrome; therefore, only 16 patients from 15 families have been described, and new phenotypic features continue to be added. In this report, we describe 2 newly identified patients with Wiedemann-Steiner syndrome who presented with variable severity...
October 24, 2016: Journal of Child Neurology
X M Lü, C Feng, Y F Dong, G Fu, Y Guo
Objective: To explore the influence of the labro-chondral complex (LLC) on the development of the acetabulum after close reduction in developmental dysplasia of the hip (DDH). Methods: Sixty-one cases (72 hips) with DDH presented in Beijing Jishuitan Hospital were reviewed, all the patients were treated by closed reduction, arthrogram and Spica casting from March 2010 to December 2013. The anterior-posterior pelvic radiography was performed to evaluate the morphology of the labro-chondral complex and reduction of the hip...
October 11, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Atul Bhaskar, Hardik Desai, Gaurav Jain
BACKGROUND: Re-dislocation after primary treatment of developmental dysplasia of the hip is a serious complication. We analyzed the various risk factors that contribute to re-dislocation, and whether the bony ossific nucleus (ON) confers increased stability against re-dislocation. MATERIALS AND METHODS: Fifty-five children (60 hips) were classified into three treatment groups: Closed reduction (CR) in 15 children (17 hips), open reduction (OR) in 26 children (28 hips), and OR with bony surgery (ORB) in 14 children (15 hips)...
September 2016: Indian Journal of Orthopaedics
Vikesh V Chandaria, James McGinty, Niamh C Nowlan
Mechanical forces due to fetal movements play an important role in joint shape morphogenesis, and abnormalities of the joints relating to abnormal fetal movements can have long-term health implications. While mechanical stimulation during development has been shown to be important for joint shape, the relationship between the quantity of mechanical stimulation and the growth and shape change of developing cartilage has not been quantified. In this study, we culture embryonic chick limb explants in vitro in order to reveal how the magnitude of applied movement affects key aspects of the developing joint shape...
October 12, 2016: Journal of Biomechanics
Xuyi Wang, Jianping Peng, De Li, Linlin Zhang, Hui Wang, Leisheng Jiang, Xiaodong Chen
BACKGROUND: The success of Bernese periacetabular osteotomy depends significantly on how extent the acetabular fragment can be corrected to its optimal position. This study was undertaken to investigate whether correcting the acetabular fragment into the so-called radiological "normal" range is the best choice for all developmental dysplasia of the hip with different severities of dysplasia from the biomechanical view? If not, is there any correlation between the biomechanically optimal position of the acetabular fragment and the severity of dysplasia? METHODS: Four finite element models with different severities of dysplasia were developed...
October 4, 2016: Journal of Orthopaedic Surgery and Research
L J Ding, Y L Liu, G Ma, Y Q Jia, Y S H Wei, X M Liu
This study aimed to determine whether abnormal apoptosis is present in acetabular cartilage in early developmental dislocations of the hip (DDH), and if so, whether it is correlated with the expression of caspase-3 and Bcl-2. DDH was induced in 24 4-week-old New Zealand white rabbits. Acetabular cartilage specimens from the experimental and control groups were stained with hematoxylin and eosin (H&E). Animals from the experimental group developed acetabular dysplasia. Apoptotic chondrocytes were observed by ultrastructural electron microscopy and H&E...
September 23, 2016: Genetics and Molecular Research: GMR
Fatemeh Saberi Hosnijeh, Maria E Zuiderwijk, Mathijs Versteeg, Hieronymus T W Smeele, Albert Hofman, André G Uitterlinden, Rintje Agricola, Edwin H G Oei, Jan H Waarsing, Sita M Bierma-Zeinstra, Joyce B J van Meurs
Objectives Cam deformity and acetabular dysplasia have been recognized as relevant risk factors for hip osteoarthritis (OA) in a few prospective studies with limited sample sizes. However, to date, there is no evidence available from prospective studies if the magnitude of these associations differ by gender, body mass index (BMI), and age. Methods Participants of Rotterdam Study cohort including men and women aged 55 years or older without OA at baseline (n=4438) and mean follow-up of 9.2 years were included in the study...
October 1, 2016: Arthritis & Rheumatology
T Amano, Y Hasegawa, T Seki, Y Takegami, K Murotani, N Ishiguro
AIMS: The influence of identifiable pre-operative factors on the outcome of eccentric rotational acetabular osteotomy (ERAO) is unknown. We aimed to determine the factors that might influence the outcome, in order to develop a scoring system for predicting the prognosis for patients undergoing this procedure. PATIENTS AND METHODS: We reviewed 700 consecutive ERAOs in 54 men and 646 women with symptomatic acetabular dysplasia or early onset osteoarthritis (OA) of the hip, which were undertaken between September 1989 and March 2013...
October 2016: Bone & Joint Journal
Stephanie Pun
Hip dysplasia is a treatable developmental disorder that presents early in life but if neglected can lead to chronic disability due to pain, decreased function, and early osteoarthritis. The main causes of hip dysplasia in the young adult are residual childhood developmental dysplasia of the hip (DDH) and adolescent-onset acetabular dysplasia. These two distinct disease processes affect the growing hip during different times of development but result in a similar deformity and pathomechanism of hip degeneration...
September 9, 2016: Current Reviews in Musculoskeletal Medicine
Lucas A Anderson, Mike B Anderson, Jill A Erickson, Jesse Chrastil, Christopher L Peters
BACKGROUND: The anterior wall index (AWI) and posterior wall index (PWI) have been proposed to quantify anterior and posterior acetabular coverage using AP pelvic radiographs. However, these indices have only been reported in symptomatic patients with apparent pathomorphologies (dysplasia, overcoverage, and retroversion) undergoing osteochondroplasty or reorientation osteotomy. QUESTIONS: (1) What are the ranges for AWI and PWI from measurements obtained on AP pelvic radiographs of asymptomatic senior athletes with well-functioning hips? (2) Is there a difference between the AWI and PWI in asymptomatic athletes with acetabular morphology consistent with acetabular dysplasia, overcoverage, and retroversion when compared with asymptomatic hips that do not meet the radiographic definitions for those morphologies (controls)? METHODS: Five hundred five athletes (998 asymptomatic native hips) were independently evaluated by two readers on AP pelvic radiographs for AWI and the PWI after excluding hips with prior surgery, inadequate radiographs, or poor function (modified Harris hip score < 80)...
September 6, 2016: Clinical Orthopaedics and related Research
Zhendong Zhang, Qi Zhuo, Wei Chai, Ming Ni, Heng Li, Jiying Chen
Periprosthetic femoral fracture (PFF) is a complicated complication of both primary and revision hip arthroplasty with an increasing incidence. The present study aimed to summarize the clinical characteristics and identify the risk factors for PFF which would be potentially helpful in the prevention and treatment of PFF.We retrospectively analyzed the clinical data of 89 cases of PFF, and a case-control study was designed to identify the potential risk for intraoperative and postoperative PFF in both primary and revision hip arthroplasty...
August 2016: Medicine (Baltimore)
Wojciech Kiebzak, Arkadiusz Żurawski, Michał Dwornik
BACKGROUND: Developmental dysplasia of the hip joint is one of the most common congenital defects and often results in functional and structural disorders. Such cases particularly demand optimizing therapeutic effects and maximally reducing the duration of therapy. PURPOSE: The aim of this case report is to present the therapeutic process in a child with developmental hip dysplasia. CASE REPORT: This is a case report of a female child with a birth weight of 2,800 g and an Apgar score of 9 points born to a gravida 3 para 3 mother at 37 weeks...
2016: Therapeutics and Clinical Risk Management
Yohei Kagawa, Hirosuke Endo, Tomonori Tetsunaga, Yosuke Fujii, Takamasa Miyake, Toshifumi Ozaki
BACKGROUND: Treatment of hip dislocation diagnosed after walking age is often difficult. We report the surgical treatment of these patients by open reduction with a soft tissue surgical procedure without osteotomy. METHODS: Thirty-eight children (43 hips) diagnosed with complete dislocation of the hip after walking age were included in this study. We radiographically analysed postoperative hip joint development up to 6 years of age. To assess the predictors of acetabular development, we evaluated the radiographs, using an acetabular index of ≤35° and a centre-edge angle of >5° at 6 years of age as satisfactory outcomes, and evaluated the advance of acetabular development over time...
August 12, 2016: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
Taghi Baghdadi, Reza Abdi, Ramin Zargar Bashi, Hossein Aslani
BACKGROUND: Children with myelomeningocele (MMC) develop a wide variety of hip deformities such as muscle imbalance, contracture, subluxation, and dislocation. Various methods and indications have been introduced for treatment of muscle imbalances and other hip problems in patients with MMC but there is no study or meta-analysis to compare the results and complications. This review aims to find the most acceptable approach to hip problems in patients with MMC. METHODS: MEDLINE was searched up to April 2015...
June 2016: Archives of Bone and Joint Surgery
Anil Kumar Gupta, Kumar Keshav, Praganesh Kumar
BACKGROUND: The quest for ideal bone graft substitutes still haunts orthopedic researchers. The impetus for this search of newer bone substitutes is provided by mismatch between the demand and supply of autogenous bone grafts. Bone banking facilities such as deep frozen and freeze-dried allografts are not so widely available in most of the developing countries. To overcome the problem, we have used partially decalcified, ethanol preserved, and domestic refrigerator stored allografts which are economical and needs simple technology for procurement, preparation, and preservation...
July 2016: Indian Journal of Orthopaedics
Robert F Murphy, Young-Jo Kim
In pediatric patients with developmental dysplasia of the hip with late presentation or failure of nonsurgical treatment, surgical management is indicated. The goal of surgery is to obtain a stable reduction to promote development of the femoral head and acetabulum while avoiding osteonecrosis of the femoral head and the need for further surgery. Treatment is related to the age of the patient and the degree of soft-tissue contracture or bony deformity present. As a general rule, in children aged <12 months, closed reduction and spica casting is preferred...
September 2016: Journal of the American Academy of Orthopaedic Surgeons
Baran Sarıkaya, Serkan Sipahioğlu, Zeynep Bekin Sarıkaya, Mehmet Akif Altay, Uğur Erdem Işıkan
OBJECTIVES: This study aims to evaluate the relationship of early-term radiological changes with development of the hip joint after Pemberton osteotomy. PATIENTS AND METHODS: This study, which was conducted between January 2010 and December 2014, included 101 hips (26 bilateral) of 75 patients (25 males, 50 females; mean age 31.5 months; range 15 to 71 months) which were performed Pemberton osteotomy due to developmental dysplasia of the hip. Radiologically, we assessed the parameters of center-edge angle, acetabular index (AI), and acetabular depth index (ADI)...
August 2016: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
Andrea B Mosler, Kay M Crossley, Jan H Waarsing, Nabil Jomaah, Adam Weir, Per Hölmich, Rintje Agricola
BACKGROUND: Participation in high-impact athletic activities has recently been associated with a higher prevalence of cam deformity. Bony hip morphology has also emerged as an important factor in the development of hip osteoarthritis. However, it is unknown whether bony morphology differs between ethnicities in athletes participating in high-impact sports. PURPOSE: To investigate whether the prevalence of specific bony hip morphological abnormalities differed between professional male soccer players of diverse ethnic backgrounds...
August 4, 2016: American Journal of Sports Medicine
Ena Colo, Wim H C Rijnen, Jean W M Gardeniers, Albert van Kampen, B Willem Schreurs
BACKGROUND: Developmental dysplasia of the hip (DDH) is a common cause of secondary osteoarthritis (OA) in younger patients, and when end-stage OA develops, a THA can provide a solution. Different options have been developed to reconstruct these defects, one of which is impaction bone grafting combined with a cemented cup. To determine the true value of a specific technique, it is important to evaluate patients at a long-term followup. As there are no long-term studies, to our knowledge, on THA in patients with DDH using impaction bone grafting with a cemented cup, we present the results of this technique at a mean of 15 years in patients with previous DDH...
November 2016: Clinical Orthopaedics and related Research
Satoko Ohfuji, Seiya Jingushi, Kyoko Kondo, Muroto Sofue, Moritoshi Itoman, Tadami Matsumoto, Yoshiki Hamada, Hiroyuki Shindo, Yoshio Takatori, Harumoto Yamada, Yuji Yasunaga, Hiroshi Ito, Satoshi Mori, Ichiro Owan, Genji Fujii, Hirotsugu Ohashi, Shinji Takahashi, Yoshio Hirota
BACKGROUND: In Japan, the majority of hip osteoarthritis (OA) was caused by acetabular dysplasia, and about 90 % of patients were female. The present study focused on Japanese female patients with hip OA due to acetabular dysplasia, and examined the associated factors with OA staging at diagnosis, in special reference to body weight. METHODS: Study subjects were 336 Japanese women who were newly diagnosed with hip OA caused by acetabular dysplasia at 15 hospitals in 2008...
2016: BMC Musculoskeletal Disorders
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