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development dysplasia of the hip

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https://www.readbyqxmd.com/read/29755196/effect-of-a-commercially-available-fish-based-dog-food-enriched-with-nutraceuticals-on-hip-and-elbow-dysplasia-in-growing-labrador-retrievers
#1
Sabrina Manfredi, Francesco Di Ianni, Nicola Di Girolamo, Sergio Canello, Giacomo Gnudi, Gianandrea Guidetti, Francesca Miduri, Martina Fabbi, Eleonora Daga, Enrico Parmigiani, Sara Centenaro, Antonella Volta
The aim of this study was to evaluate the prevalence of hip and elbow dysplasia in a group of growing Labrador retrievers fed a fish-based diet enriched with nutraceuticals with chondroprotective properties. The puppies ranged from 3 to 12 mo of age and were divided into 2 groups, each fed a different diet. The control diet consisted of a high quality, chicken-based dog food, while the test diet was a fish-based dog food, enriched with nutraceuticals. Hip and elbow joints were radiographed and scored at 6 and 12 mo of age...
April 2018: Canadian Journal of Veterinary Research, Revue Canadienne de Recherche Vétérinaire
https://www.readbyqxmd.com/read/29735473/exercise-therapy-interventions-in-patients-with-hip-osteoarthritis-comparison-of-the-effects-of-dvd-and-website-based-interventions
#2
Yuko Uesugi, Junichiro Koyanagi, Keishi Takagi, Ryota Yamaguchi, Shinya Hayashi, Takashi Nishii
BACKGROUND: Prevalence of developmental hip dysplasia is high in Japan. Exercise therapy has been proven effective to treat certain aspects of hip osteoarthritis. Moreover, therapy provided via digital video discs (DVDs) and websites allows patients to exercise in the comfort of their own homes. However, no studies have evaluated the effectiveness of visual instructions in patients with hip disorders. OBJECTIVE: This study aimed to compare the effectiveness of exercise therapy administered via DVD and that administered via a website...
May 7, 2018: JMIR Rehabilitation and Assistive Technologies
https://www.readbyqxmd.com/read/29716513/developmental-dysplasia-of-the-hip-addressing-evidence-gaps-with-a-multicentre-prospective-international-study
#3
Emily K Schaeffer, Ihdi Study Group, Kishore Mulpuri
There is a lack of high quality evidence available to guide clinical practice in the treatment and management of developmental dysplasia of the hip (DDH). Evidence has been limited by persistent confusion on diagnostic and classification terminology, variability in surgeon decision making and a reliance on single centre, retrospective studies with small patient numbers. To address gaps in knowledge regarding screening, diagnosis and management of DDH, the International Hip Dysplasia Institute began a multicentre, international prospective study on infants with hips dislocated at rest...
May 7, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29693206/3d-printed-model-improves-clinical-assessment-of-surgeons-on-anatomy
#4
Bin Zheng, Xiaolin Wang, Yixiong Zheng, Jiexiong Feng
Performing surgical procedures often requires a surgeon to develop a skill to create 3-dimensional (3D) mental model on patient's anatomy. Question remains whether the touching on the 3D printed model can facilitate learning of patient anatomy than viewing the rendered virtual on-screen model. The printed and the virtual 3D model were developed from CT films taken from a 4-year-old girl, who had dysplasia of the hip in the left hip. Eleven subjects were called to report measures on six key anatomical features on the hips...
April 24, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29662652/guided-bone-regeneration-using-a-bone-tissue-engineering-complex-consisting-of-a-poly-dl-lactide-membrane-and-bone-mesenchymal-stem-cells
#5
Dahui Wang, Yifeng Lin, Lian Chen, Yueqiang Mo, Peng Huang, Ruixue Ma
Developmental dysplasia of the hip (DDH) is one of the most common diseases encountered in pediatric orthopedic departments. Current treatment strategies seek to improve acetabular coverage, the principal defect of acetabular dysplasia, but are not very successful. We developed a guided bone regeneration (GBR) strategy to improve acetabular coverage via bone tissue engineering (BTE). Poly- dl -lactide (PDLLA) membranes were seeded with bone marrow mesenchymal stem cells (BMSCs) to form a BTE complex, which was then implanted into the superior margin of the acetabulum in a rabbit DDH model...
March 27, 2018: Oncotarget
https://www.readbyqxmd.com/read/29643866/joint-genomic-prediction-of-canine-hip-dysplasia-in-uk-and-us-labrador-retrievers
#6
Stefan M Edwards, John A Woolliams, John M Hickey, Sarah C Blott, Dylan N Clements, Enrique Sánchez-Molano, Rory J Todhunter, Pamela Wiener
Canine hip dysplasia, a debilitating orthopedic disorder that leads to osteoarthritis and cartilage degeneration, is common in several large-sized dog breeds and shows moderate heritability suggesting that selection can reduce prevalence. Estimating genomic breeding values require large reference populations, which are expensive to genotype for development of genomic prediction tools. Combining datasets from different countries could be an option to help build larger reference datasets without incurring extra genotyping costs...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29486210/whole-genome-sequencing-of-pairwise-human-subjects-reveals-dna-mutations-specific-to-developmental-dysplasia-of-the-hip
#7
Lun-Qing Zhu, Guang-Hao Su, Jin Dai, Wen-Yan Zhang, Chun-Hua Yin, Fu-Yong Zhang, Zhen-Hua Zhu, Zhi-Xiong Guo, Jian-Feng Fang, Cheng-da Zou, Xing-Guang Chen, Ya Zhang, Cai-Ying Xu, Yun-Fang Zhen, Xiao-Dong Wang
Developmental dysplasia of the hip (DDH) is a common congenital malformation characterized by mismatch in shape between the femoral head and acetabulum, and leads to hip dysplasia. To date, the pathogenesis of DDH is poorly understood and may involve multiple factors, including genetic predisposition. However, comprehensive genetic analysis has not been applied to investigate a genetic component of DDH. In the present study, 10 pairs of healthy fathers and DDH daughters were enrolled to identify genetic hallmarks of DDH using high throughput whole genome sequencing...
February 25, 2018: Genomics
https://www.readbyqxmd.com/read/29481347/the-2018-nicholas-andry-award-the-evidence-base-for-the-treatment-of-developmental-dysplasia-of-the-hip-the-iowa-contribution
#8
Stuart L Weinstein, Lori A Dolan, Jose A Morcuende
This review summarizes evidence developed at the University of Iowa concerning the management and outcomes of developmental dysplasia of the hip beginning with the observations and analyses of Dr Arthur Steindler in the early 1900s. The strong evidence-based practice tradition established by Steindler 100 years ago continues as we critically evaluate our procedures and patient outcomes, only altering approaches when warranted by strong personal and research evidence. Our practice continues to be conservative in that we strive to produce the best environment possible for the hip to develop on its own and operate only when less invasive methods have failed...
May 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29435594/-periacetabular-osteotomy-what-influence-does-age-have-on-patient-relevant-results-a-prospective-5%C3%A2-year-investigation
#9
L Franken, F Thielemann, A Postler, S Blum, A Hartmann, K-P Günther, J Goronzy
INTRODUCTION: Periacetabular osteotomy (PAO) is an effective procedure in treatment of symptomatic hip dysplasia. To achieve a good outcome a strict patient selection has to be applied. The aim of this study was to evaluate the influence of patient age at surgery on clinical outcome. METHODS: In a prospective study 86 patients (106 hips) underwent clinical and radiographic follow-up at a mean time of 5 years (2.5-8.5 years) after PAO. Patient-related outcome measurements (PROMs: EQ-5D, WOMAC, OHS, GTO) were applied preoperatively as well as postoperatively and the deformity correction as well as development of osteoarthritis were evaluated...
March 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29429067/hip-malformation-is-a-very-common-finding-in-young-patients-scheduled-for-total-hip-arthroplasty
#10
Dennis Karimi, Thomas Kallemose, Anders Troelsen, Jakob Klit
INTRODUCTION: In Denmark, 20% of all registered total hip arthroplasties (THA) from 1995 to 2014 has been patients younger than 60 years with primary idiopathic osteoarthritis (OA). It is speculated that hip malformations may be a major contributor to early OA development. It has been shown that hip malformation may compromise implant position and, therefore, identifying and knowing the incidence of malformations is important. Our aim was to assess the prevalence and type of hip malformations in a cohort of younger patients undergoing THA...
April 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29423245/refractory-pain-following-hip-arthroscopy-evaluation-and-management
#11
REVIEW
Jason J Shin, Darren L de Sa, Jeremy M Burnham, Craig S Mauro
With increased knowledge and understanding of hip pathology, hip arthroscopy is rapidly becoming a popular treatment option for young patients with hip pain. Despite improved clinical and radiographic outcomes with arthroscopic treatment, some patients may have ongoing pain and less than satisfactory outcomes. While the reasons leading to failed hip arthroscopy are multifactorial, patient selection, surgical technique and rehabilitation all play a role. Patients with failed hip arthroscopy should undergo a thorough history and physical examination, as well as indicated imaging...
January 2018: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/29382681/evaluating-the-role-of-prereduction-hip-traction-in-the-management-of-infants-and-children-with-developmental-dysplasia-of-the-hip-ddh-protocol-for-a-systematic-review-and-planned-meta-analysis
#12
Sarah Walton, Emily Schaeffer, Kishore Mulpuri, Peter Cundy, Nicole Williams
INTRODUCTION: Developmental dysplasia of the hip (DDH) affects 4-6 per 1000 live births in developed countries. Effective treatment to realign the hip is necessary to avoid long-term morbidities and maximise functional outcome. Treatment options depend on patient age but typically involve hip bracing and/or reduction under general anaesthetic. Some centres also employ prereduction hip traction. Historical papers suggest traction reduces risk of avascular necrosis (AVN) femoral head and reduces requirement for open reduction...
January 29, 2018: BMJ Open
https://www.readbyqxmd.com/read/29350271/development-of-unstable-hips-after-treatment-with-the-t%C3%A3-bingen-splint-mid-term-follow-up-of-83-hip-joints
#13
Hannes Kubo, Hakan Pilge, Karoline Nepp, Bettina Westhoff, Ruediger Krauspe
INTRODUCTION: Early diagnosis and treatment of hip dysplasia are widely accepted as major factors for beneficial outcome. However, modalities for reduction and retention as well as for imaging are currently under clinical investigation. Local and general risk factors, e.g., breech presentation and the family's desire to avoid in-hospital treatment are major concerns in the decision-making process and consultation. For treatment of unstable hips in newborns the treatment with the Tübingen splint has proven good results in recent studies...
January 19, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29310681/comparison-of-outcome-measures-and-complication-rates-following-three-different-approaches-for-primary-total-hip-arthroplasty-a-pragmatic-randomised-controlled-trial
#14
Adrian J Talia, Cassandra Coetzee, Oren Tirosh, Phong Tran
BACKGROUND: Total hip arthroplasty is one of the most commonly performed surgical procedures worldwide. There are a number of surgical approaches for total hip arthroplasty and no high-level evidence supporting one approach over the other. Each approach has its unique benefits and drawbacks. This trial aims to directly compare the three most common surgical approaches for total hip arthroplasty. METHODS/DESIGN: This is a single-centre study conducted at Western Health, Melbourne, Australia; a large metropolitan centre...
January 8, 2018: Trials
https://www.readbyqxmd.com/read/29285666/acetabular-index-is-the-best-predictor-of-late-residual-acetabular-dysplasia-after-closed-reduction-in-developmental-dysplasia-of-the-hip
#15
YiQiang Li, YueMing Guo, Ming Li, QingHe Zhou, Yuanzhong Liu, WeiDong Chen, JingChun Li, Federico Canavese, HongWen Xu
PURPOSE: Our objective was to find the best predictor of late residual acetabular dysplasia in developmental dysplasia of the hip (DDH) after closed reduction (CR) and discuss the indications for secondary surgery. METHODS: We retrospectively reviewed the records of 89 patients with DDH (mean age 16.1 ± 4.6 months; 99 hips) who were treated by CR. Hips were divided into three groups according to final outcomes: satisfactory, unsatisfactory and operation. The changes in the acetabular index (AI), centre-edge angle of Wiberg (CEA), Reimer's index (RI) and centre-head distance discrepancy (CHDD) over time among groups were compared...
March 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29250336/preoperative-planning-for-redirective-periacetabular-osteotomies
#16
REVIEW
Christoph E Albers, Piet Rogers, Nicholas Wambeek, Sufian S Ahmad, Piers J Yates, Gareth H Prosser
Redirective, periacetabular osteotomies (PAO) represent a group of surgical procedures for treatment of developmental dysplasia of the hip (DDH) in skeletally mature and immature patients. The ultimate goal of all procedures is to reduce symptoms, improve function and delay or prevent progression of osteoarthritis. During the last two decades, the understanding of the underlying pathomechanisms has continuously evolved. This is mainly attributable to the development of the femoroacetabular impingement concept that has increased the awareness of the underlying three-dimensional complexity associated with DDH...
December 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/29227567/canine-hip-dysplasia-a-natural-animal-model-for-human-developmental-dysplasia-of-the-hip
#17
Cecilia Pascual-Garrido, Farshid Guilak, M Farooq Rai, Michael D Harris, Mandi J Lopez, Rory J Todhunter, John C Clohisy
Developmental dysplasia of the hip (DDH) in humans is a common condition that is associated with hip pain, functional limitations, and secondary osteoarthritis (OA). Surgical treatment of DDH has improved in the last decade, allowing excellent outcomes at short- and mid-term follow-up. Still, the etiology, mechanobiology, and pathology underlying this disease are not well understood. A pre-clinical animal model of DDH could help advance the field with a deeper understanding of specific pathways that initiate hip joint degeneration secondary to abnormal biomechanics...
December 11, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29209742/the-prevalence-and-risk-factors-for-delayed-union-of-the-superior-pubic-ramus-at-one-year-after-curved-periacetabular-osteotomy-its-risk-factor-and-outcome
#18
Ayumi Matsunaga, Shunsuke Akiho, Koichi Kinoshita, Masatoshi Naito, Takuaki Yamamoto
PURPOSE: Curved periacetabular osteotomy (CPO) has been developed for the treatment of acetabular dysplasia. While several studies have reported its good clinical results, the complications of CPO include delayed union and nonunion of the superior pubic ramus. The purpose of this study is to investigate the prevalence of delayed union of the pubis one year after CPO, and to determine the risk factors for this complication. METHODS: The study examined 113 hips that underwent CPO between 2008 and 2012...
December 5, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29201383/an-autosomal-recessive-mutation-in-scl24a4-causing-enamel-hypoplasia-in-samoyed-and-its-relationship-to-breed-wide-genetic-diversity
#19
Niels C Pedersen, Bonnie Shope, Hongwei Liu
Background: Pure breeding of dogs has led to over 700 heritable disorders, of which almost 300 are Mendelian in nature. Seventy percent of the characterized mutations have an autosomal recessive mode of inheritance, indicative of positive selection during bouts of inbreeding primarily for new desired conformational traits. Samoyed suffer from several common complex genetic disorders, but up to this time only two X-linked and one autosomal dominant disorder have been identified. Previous studies based on pedigrees and SNP arrays have concluded that Samoyed breeders have done a good job in maintaining genetic diversity and avoiding excessive inbreeding...
2017: Canine Genetics and Epidemiology
https://www.readbyqxmd.com/read/29200486/a-minimally-invasive-technique-using-a-modified-stoppa-approach-for-periacetabular-osteotomy-a-preliminary-cadaveric-study
#20
Turgut Akgul, Osman Coskun, Murat Korkmaz, Ilke Ali Gurses, Cengiz Sen, Ozcan Gayretli
Background: Developmental hip dysplasia is diagnosed when the femoral head is not sufficiently covered by the acetabulum. Anterior and lateral cover deficiency is seen, as a result a dysplastic hip joint. Various incision modifications have been developed because of the muscle dissection and wide wound scar in Smith-Peterson incision, which was originally used in Bernese osteotomy. This study evaluates applicability of the modified Stoppa approach in the performance of Bernese periacetabular osteotomy (PAO)...
November 2017: Indian Journal of Orthopaedics
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