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Knee substitution

Kwang-Jun Oh, Young-Bong Ko, Sagar Jaiswal, In-Cheul Whang
The purpose of this study was to compare the osteoconductivity, and absorbability of hydroxyapatite or beta-tricalcium phosphate in clinical scenario of opening wedge high tibial osteotomy Total 41 knees of 40 patients with follow up period of more than 1 year were enrolled. These patients were divided into two groups, Group I (22 knees, 21 patients) used hydroxyapatite and Group II (19 knees, 19 patients) used beta-tricalcium phosphate as a substitute in the opening gap. According to proven method, the osteoconductivity was assessed radiographically by the extent of new bone formation at osteotomy space and absorbability was evaluated by measuring the area occupied by substitute at immediate postoperative, postoperative 6 months and 1 year...
December 2016: Journal of Materials Science. Materials in Medicine
Priyanka Srivastava, Himani Pandey, Divya Agarwal, Kausik Mandal, Shubha R Phadke
We describe three consanguineous Indian families with a distinct form of spondyloepiphyseal dysplasia (SED Omani type). It is an autosomal recessive disorder due to mutation in CHST3 gene. CHST3 gene encodes the enzyme chondroitin 6-O-sulfotransferase-1 (C6ST-1) which mediates the sulfation of proteoglycans, (chondroitin sulfate), in the extracellular matrix of cartilage. CHST3 gene was sequenced in probands from three different families with SED. In two families missense mutations (c.904G>C predicting the substitution D302H) and c...
October 18, 2016: American Journal of Medical Genetics. Part A
Takashi Daiho, Kazuo Yamasaki, Stefania Danko, Hiroshi Suzuki
The cytoplasmic Actuator domain of sarco(endo)plasmic reticulum Ca(2+)-ATPase undergoes large rotational movements that influence the distant transmembrane transport sites, and a long second transmembrane helix (M2) connected with this domain plays critical roles in transmitting motions between the cytoplasmic catalytic domains and transport sites. Here we explore possible structural roles of Gly(105) between the cytoplasmic (M2c) and transmembrane (M2m) segments of M2 by introducing mutations that limit/increase conformational freedom...
October 12, 2016: Journal of Biological Chemistry
Lauren A Beaupre, B Sharifi, D W C Johnston
BACKGROUND: This 10-year follow-up compares health-related quality of life (HRQL) and reoperations in 100 subjects who were randomized to receive posterior cruciate ligament substituting (PS) or posterior cruciate ligament retaining (CR) total knee arthroplasty. We previously reported 2-year results. METHODS: Subjects were enrolled preoperatively and randomized at surgery. Subjects completed HRQL questionnaires at all evaluation points. Subjects were re-evaluated at 2 and 10 years with reoperations determined through regional medical record review and patient report...
September 8, 2016: Journal of Arthroplasty
Hiroshi Higuchi, Atsushi Kobayashi, Keiko Ikeda, Kazuhisa Hatayama, Sinya Yanagisawa, Kazuo Kato
This prospective pilot study investigated whether grafting β-tricalcium phosphate (B-TCP) into the bone-patellar tendon-bone (BPTB)-harvesting site after anterior cruciate ligament reconstruction would accelerate bone and tendon regeneration in the grafted site. Overall, 19 patients agreed prospectively to undergo regular morphological and histological examinations of the B-TCP-grafted site. Postoperative radiographic, ultrasonographic, and magnetic resonance imaging (MRI) examinations were performed to evaluate the grafted site at 1, 3, 6, and 12 months...
September 28, 2016: Journal of Knee Surgery
Jörg Lützner, Franziska Beyer, Julian Dexel, Hagen Fritzsche, Cornelia Lützner, Stephan Kirschner
PURPOSE: The use of an ultracongruent (UC) insert with a standard femoral component for substitution of the posterior cruciate ligament (PCL) is a bone-preserving and therefore interesting alternative to the established box and cam mechanism of posterior stabilized (PS) total knee arthroplasty (TKA). This study investigated range of motion (ROM), stability and patient-reported outcome (PRO) in UC and PS TKA. We hypothesized better knee flexion with the PS design but no difference in stability and PRO between UC and PS TKA...
September 22, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Yoshinori Ishii, Hideo Noguchi, Junko Sato, Tetsuya Sakurai, Shin-Ichi Toyabe
PURPOSE: Quadriceps strength impairment after total knee arthroplasty (TKA) continues to be a concern. However, most studies of quadriceps strength have short-term follow-up periods. Whether quadriceps strength impairment occurs in the long-term follow-up period after TKA remains unclear. The purpose of this study was to compare the quadriceps strength between posterior cruciate ligament-retaining (CR) and substituting (PS) design mobile-bearing TKA (1) in the same patients after an average of 10 years and (2) between TKA patients and age-matched controls...
September 20, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Lubhani Jain, Namrata Gupta, Mamatha M Reddy, Ruchi Mittal, Manas Ranjan Barik, Bharat Panigrahi, Tom Monie, Soumyava Basu
We report a 12-year-old girl who presented with bilateral granulomatous anterior uveitis accompanied by boggy arthritis of knee and ankle joints, intermittent fever, and nodular skin rash. She was diagnosed with sporadic Blau syndrome (early-onset sarcoidosis) based on above clinical signs and presence of non-necrotising granuloma on iris biopsy. DNA sequencing revealed a previously unreported heterozygous mutation consisting of a G>A transition in exon 4 of the NOD2 gene. This resulted in a glutamic acid to lysine substitution in helical domain 2 of the nucleotide binding and oligomerization (NACHT) region, possibly reducing efficiency of auto-inhibition in NOD2 signaling...
September 13, 2016: Ocular Immunology and Inflammation
A Neufang, S Savvidis
BACKGROUND: The use of autologous superficial femoral veins (SFV) as an arterial or venous substitute represents a valuable technique in modern vascular surgery with versatile indications. The SFV autografts exhibit excellent control of infection and durable long-term results in terms of graft patency in prosthetic or arterial infections. In cases of elective use of the SFV, duplex ultrasound evaluation of the deep leg vein system should be implemented to confirm the patency of the profunda femoris vein...
2016: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
Shinichi Kuriyama, Masahiro Ishikawa, Shinichiro Nakamura, Moritoshi Furu, Hiromu Ito, Shuichi Matsuda
BACKGROUND: There are several causes of patient dissatisfaction after total knee arthroplasty (TKA). This study hypothesized that noise occurring in the knee would worsen patient satisfaction after TKA. METHODS: We mailed a newly developed questionnaire to 103 consecutive participants who were followed for one year, resulting in data from 61 knees in 60 patients (47 women and 13 men, mean age 73 years) who underwent cruciate-substituting TKA. We evaluated postoperative range of motion, knee instability, and the 2011 Knee Society Score in terms of noise generation after TKA...
July 21, 2016: Journal of Arthroplasty
E A van IJsseldijk, E R Valstar, B C Stoel, R G H H Nelissen, N Baka, R Van't Klooster, B L Kaptein
OBJECTIVES: An important measure for the diagnosis and monitoring of knee osteoarthritis is the minimum joint space width (mJSW). This requires accurate alignment of the x-ray beam with the tibial plateau, which may not be accomplished in practice. We investigate the feasibility of a new mJSW measurement method from stereo radiographs using 3D statistical shape models (SSM) and evaluate its sensitivity to changes in the mJSW and its robustness to variations in patient positioning and bone geometry...
August 2016: Bone & Joint Research
Gaetano Caruso, Emanuele Gerace, Vincenzo Lorusso, Rosario Cultrera, Loredana Moretti, Leo Massari
BACKGROUND: Chronic osteomyelitis is a challenging problem, and malignant transformation is a rare occurrence. We report a case of a patient with squamous cell carcinoma arising from an osteomyelitic hotbed and discuss through a literature review the etiopathogenesis, diagnosis, and treatment of this lesion. CASE PRESENTATION: A 69-year-old Italian man had sustained an exposed tibial fracture 40 years ago during a road accident, for which he had undergone various surgical osteosynthesis treatments with multiple antibiotic therapies...
2016: Journal of Medical Case Reports
Lukas Leitner, Ewald Musser, Norbert Kastner, Jörg Friesenbichler, Daniela Hirzberger, Roman Radl, Andreas Leithner, Patrick Sadoghi
Red blood cell concentrates (RCC) substitution after total knee arthroplasty (TKA) is correlated with multifold of complications and an independent predictor for higher postoperative mortality. TKA is mainly performed in elderly patients with pre-existing polymorbidity, often requiring permanent preoperative antithrombotic therapy (PAT). The aim of this retrospective analysis was to investigate the impact of demand for PAT on inpatient blood management in patients undergoing TKA. In this study 200 patients were retrospectively evaluated after TKA for differences between PAT and non-PAT regarding demographic parameters, preoperative ASA score > 2, duration of operation, pre-, and intraoperative hemoglobin level, and postoperative parameters including amount of wound drainage, RCC requirement, and inpatient time...
2016: Scientific Reports
Yoshinori Ishii, Hideo Noguchi, Junko Sato, Tetsuya Sakurai, Shin-Ichi Toyabe
PURPOSE: It is still controversial whether anteroposterior (AP) translation magnitude after total knee arthroplasty (TKA) affects clinical outcomes, particularly range of motion (ROM). This study examined the following two questions: (1) are AP translations at the mid- and long-term follow-up different for knees within the same patient treated with posterior cruciate ligament-retaining (PCLR) versus posterior cruciate ligament-substituting (PCLS) mobile-bearing TKA prosthesis designs? (2) Is the ROM at the mid- and long-term follow-up for knees treated with PCLR and PCLS designs correlated with the AP translation? METHODS: Thirty-seven patients undergoing sequential bilateral TKA for osteoarthritis were prospectively enrolled...
August 2, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Joanne Y Yoo, Michael J O'Malley, Laura J Matsen Ko, Steven B Cohen, Peter F Sharkey
BACKGROUND: Calcium phosphate bone substitutes (CPBS) are commonly used to augment and repair bone voids and defects after fractures around the knee joint. The purpose of this study was to determine whether prior arthroscopic application of a CPBS, for repair of magnetic resonance imaging-identified subchondral fractures associated with osteoarthritis (procedure referred to as subchondroplasty) adversely affected the performance and/or outcome of subsequent knee arthroplasty. METHODS: Twenty-two patients who had arthroscopic repair of a periarticular fracture combined with use of a CPBS who later had knee arthroplasty were identified...
October 2016: Journal of Arthroplasty
Hua-Wei Liu, Ming Ni, Guo-Qiang Zhang, Xiang Li, Hui Chen, Qiang Zhang, Wei Chai, Yong-Gang Zhou, Ji-Ying Chen, Yu-Liang Liu, Cheng-Kung Cheng, Yan Wang
BACKGROUND: This study aims to retain normal knee kinematics after knee replacement surgeries by reconstructing anterior cruciate ligament during total knee arthroplasty. METHOD: We use computational simulation tools to establish four dynamic knee models, including normal knee model, posterior cruciate ligament retaining knee model, posterior cruciate ligament substituting knee model, and anterior cruciate ligament reconstructing knee model. Our proposed method utilizes magnetic resonance images to reconstruct solid bones and attachments of ligaments, and assemble femoral and tibial components according representative literatures and operational specifications...
2016: American Journal of Translational Research
Javier Vaquero, Francisco Forriol
OBJECTIVE: the menisci are easily injured and difficult to repair. The aim of this study was to analyze the current state of meniscal surgery aimed at preserving morphology and conserving the biomechanics of the knee to prevent joint degeneration. METHODOLOGY: a search of the electronic medical literature database Medline was conducted, from The search was not limited by language. Candidate articles were identified by searching for those that included the keywords meniscus, surgery, suture, implant, allograft...
January 2016: Muscles, Ligaments and Tendons Journal
Bertrand W Parcells, Alfred J Tria
The early knee replacements were hinge designs that ignored the ligaments of the knee and resurfaced the joint, allowing freedom of motion in a single plane. Advances in implant fixation paved the way for modern designs, including the posterior-stabilized (PS) total knee arthroplasty (TKA) that sacrifices both cruciate ligaments while substituting for the posterior cruciate ligament (PCL), and the cruciate-retaining (CR) TKA designs that sacrifice the anterior cruciate ligament but retain the PCL. The early bicruciate retaining (BCR) TKA designs suffered from loosening and early failures...
May 2016: American Journal of Orthopedics
Vincent Richard, Giuliano Lamberto, Tung-Wu Lu, Aurelio Cappozzo, Raphaël Dumas
The use of multi-body optimisation (MBO) to estimate joint kinematics from stereophotogrammetric data while compensating for soft tissue artefact is still open to debate. Presently used joint models embedded in MBO, such as mechanical linkages, constitute a considerable simplification of joint function, preventing a detailed understanding of it. The present study proposes a knee joint model where femur and tibia are represented as rigid bodies connected through an elastic element the behaviour of which is described by a single stiffness matrix...
2016: PloS One
Ji-Hoon Bae, Ali Hosseini, Kyung-Wook Nha, Sang-Eun Park, Tsung Yuan Tsai, Young-Min Kwon, Guoan Li
PURPOSE: This study compared in vivo kinematic differences between Caucasian and South Korean patients after a posterior-substituting total knee arthroplasty (PS-TKA). MATERIALS AND METHODS: In vivo motions of 9 Caucasian and 13 South Korean knees with a PS-TKA during weight bearing single leg lunge were determined using a dual fluoroscopic imaging technique. Normalized tibiofemoral condylar motions and articular contact locations were analyzed. RESULTS: Femoral condylar motions of the two groups showed a similar trend in anteroposterior translation, but the South Korean patients were more anteriorly positioned than the Caucasian patients at low flexion and maximal flexion angles in both medial and lateral compartments (p<0...
June 2016: Knee Surgery & related Research
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