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https://www.readbyqxmd.com/read/28315917/a-pediatric-hypophosphatemic-rickets-on-mri-99m-tc-mdp-bone-scan-and-18-f-fdg-pet-ct
#1
Changyun Xu, Chao Ma, Yongli Bai
We present a case of a 13 years old boy who was hospitalized with a 10 months history of progressive pain and weakness in his lower extremities. The laboratory tests revealed slightly decreased phosphate and 25-hydroxyvitamin D3, high alkaline phosphatase, normal calcium and parathyroid hormone (PTH). Magnetic resonance imaging (MRI) showed multiple patchy lesions indicating bone destruction in the metaphyses and epiphyses of the left knee. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) revealed a generalized decrease of bone density in axial bones with slightly increased (18)F-FDG metabolism...
March 20, 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28278383/3d-printed-poly-%C3%AE%C2%B5-caprolactone-scaffold-augmented-with-mesenchymal-stem-cells-for-total-meniscal-substitution
#2
Zheng-Zheng Zhang, Shao-Jie Wang, Ji-Ying Zhang, Wen-Bo Jiang, Ai-Bing Huang, Yan-Song Qi, Jian-Xun Ding, Xue-Si Chen, Dong Jiang, Jia-Kuo Yu
BACKGROUND: Total meniscectomy leads to knee osteoarthritis in the long term. The poly(ε-caprolactone) (PCL) scaffold is a promising material for meniscal tissue regeneration, but cell-free scaffolds result in relatively poor tissue regeneration and lead to joint degeneration. HYPOTHESIS: A novel, 3-dimensional (3D)-printed PCL scaffold augmented with mesenchymal stem cells (MSCs) would offer benefits in meniscal regeneration and cartilage protection. STUDY DESIGN: Controlled laboratory study...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28277590/does-an-anterior-lipped-tibial-insert-adequately-substitute-for-a-post-cam-articulation-in-total-knee-arthroplasty
#3
Rahul K Biyani, Mary Ziemba-Davis, Philip H Ireland, R Michael Meneghini
INTRODUCTION: Newer tibial inserts with enhanced conformity (cruciate stabilizing anterior lip; CS) to obviate the need for a posteriorly stabilized (PS) post-cam articulation in posterior cruciate ligament-deficient knees have been recently introduced in modern total knee arthroplasty (TKA). The purpose of this study was to evaluate whether clinical and functional outcomes differ in TKA cohorts without a posterior cruciate ligament (PCL) utilizing either CS anterior-lipped or PS post-cam articulation...
March 9, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28261328/label-free-data-standardization-for-clinical-metabolomics
#4
Petr G Lokhov, Dmitri L Maslov, Oleg N Kharibin, Elena E Balashova, Alexander I Archakov
BACKGROUND: In metabolomics, thousands of substances can be detected in a single assay. This capacity motivates the development of metabolomics testing, which is currently a very promising option for improving laboratory diagnostics. However, the simultaneous measurement of an enormous number of substances leads to metabolomics data often representing concentrations only in conditional units, while laboratory diagnostics generally require actual concentrations. To convert metabolomics data to actual concentrations, calibration curves need to be generated for each substance, and this process represents a significant challenge due to the number of substances that are present in the metabolomics data...
2017: BioData Mining
https://www.readbyqxmd.com/read/28238582/do-high-flexion-total-knee-designs-increase-the-risk-of-femoral-component-loosening
#5
Young-Hoo Kim, Jang-Won Park, Jun-Shik Kim
BACKGROUND: The purpose of our prospective, randomized, long-term investigation is to compare the aseptic loosening rate of the femoral component of the total knee prosthesis and clinical and radiographic results of high-flexion posterior cruciate-substituting knee prosthesis or standard posterior cruciate-substituting knee prosthesis in the same patients. METHODS: There were 960 patients (mean age 71.3 years). The mean follow-up period was 13.2 years (range 10-14)...
February 4, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28123262/bi-cruciate-substituting-total-knee-arthroplasty-improved-medio-lateral-instability-in-mid-flexion-range
#6
Takao Kaneko, Norihiko Kono, Yuta Mochizuki, Masaru Hada, Shinya Toyoda, Yoshiro Musha
PURPOSE: Appropriate medio-lateral (ML) stability is an important factor of good clinical outcome following total knee arthroplasty (TKA). We hypothesized that a newly introduced Bi-Cruciate Stabilized substituting (BCS) prosthesis reduces the medio-lateral instability in mid-flexion range. The purpose of this study was to measure the ML stability (varus ligament balance) using a new tensor device after implantation of BCS TKA and to analysis the association between varus ligament balance and clinical results after TKA...
March 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28117634/combined-tibial-lengthening-and-ankle-arthrodesis-for-patients-with-certain-type-of-sequelae-of-poliomyelitis
#7
Chi-Chuan Wu
PURPOSE: Following far advancement of modern medicine and technology, functional disability in a certain type of sequelae of poliomyelitis may be effectively improved. METHODS: Eight consecutive adult patients with unilateral sequelae of poliomyelitis were treated. These patients had shortened lower extremity of an average of 4.8 cm (range, 4.0-5.5 cm) in the lesion side. Muscle power of the ipsilateral knee was nearly intact (grade 4 or 5) but the ankle extension was completely flaccid...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28099971/warfarin-associated-nonuremic-calciphylaxis
#8
Wesley Yung-Hsu Yu, Tina Bhutani, Rachel Kornik, Laura B Pincus, Theodora Mauro, Michael D Rosenblum, Lindy P Fox
Importance: Classic calciphylaxis associated with renal failure is a life-threatening disease. Warfarin-associated calciphylaxis without renal injury has been described, but whether it is a subset of classic calciphylaxis or a different entity remains unknown. We describe 1 case of warfarin-associated calciphylaxis, present data from 2 others from our institution, and review all cases of warfarin-associated calciphylaxis available in the literature. Our review indicates that warfarin-associated calciphylaxis is clinically and pathophysiologically distinct from classic calciphylaxis...
March 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28093635/different-intraoperative-kinematics-stability-and-range-of-motion-between-cruciate-substituting-ultracongruent-and-posterior-stabilized-total-knee-arthroplasty
#9
Hagen Fritzsche, Franziska Beyer, Anne Postler, Jörg Lützner
PURPOSE: The aim of this study was the comparison of intraoperative kinematics, stability, and range of motion (ROM) between the native osteoarthritic knee and cruciate-substituting fixed-bearing total knee arthroplasty (TKA) using both an ultracongruent (UC) and a posterior-stabilized (PS) insert design in the same patient. We hypothesized less knee flexion and less antero-posterior stability in the UC TKA. METHODS: Intraoperative measurements of kinematics, stability, and ROM were performed in 40 patients before soft-tissue release and bone cuts, and after implantation of the final femoral and tibial implants with both a UC insert and a PS insert...
January 16, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28068727/comparison-of-muscle-recovery-following-bi-cruciate-substituting-versus-posterior-stabilized-total-knee-arthroplasty-in-the-asian-population
#10
Akihito Takubo, Keinosuke Ryu, Takanori Iriuchishima, Yasuaki Tokuhashi
The purpose of this study was to compare muscle recovery in the lower extremities following the newly developed bi-cruciate substituting (BCS) to posterior stabilized (PS) total knee arthroplasty (TKA) in the Asian population. Forty-one knees in 41 patients undergoing BCS-TKA (41 female, average age: 71 ± 8.8) and 34 knees in 34 patients undergoing PS-TKA (33 female, average age: 73 ± 7.2) were included in this study. The maximum isometric power of the quadriceps and hamstring muscles was measured preoperatively, and at 1, 3, 6, and 12 months after surgery using a handheld dynamometer...
January 9, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/27984684/-anterior-knee-pain-in-knee-arthroplasty-with-or-without-a-patellar-component
#11
M Montero-Quijano, A Ceja-Barriga, J Núñez-Robles, U Barrios-Benítez, J L Núñez-Barragán, E Antonio-Romero
INTRODUCTION: The appearance of patellofemoral pain after a knee arthroplasty, particularly in rheumatic diseases, resulted in the incorporation of the substitution of the patellar component in all designs. The replacement of the patella became a standard part of knee arthroplasty, but the controversy over whether to restore it or not continues among orthopedists that perform knee arthroplasties. OBJECTIVE: To analyze the incidence of anterior knee pain in patients who underwent primary knee arthroplasty with or without replacement of the patellar component...
May 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/27908550/estimated-height-from-knee-height-or-ulna-length-and-self-reported-height-are-no-substitute-for-actual-height-in-inpatients
#12
Flávia Moraes Silva, Luciane Figueira
OBJECTIVE: The aim of this study was to evaluate the precision of estimated height from ulna length (UL) using the Malnutrition Universal Screening Tool (MUST) equation and compare it with predicted height from knee height (KH), and self-reported height in estimating actual body height in inpatients. METHODS: This cross-sectional study was carried out with patients admitted to an emergency service of a tertiary public hospital. Data were collected, at the patients' bedsides, from a specific questionnaire and anthropometric measurements...
January 2017: Nutrition
https://www.readbyqxmd.com/read/27900340/retropatellar-accessory-portals-for-improved-access-to-the-patella-anatomic-description-and-evaluation-of-safety
#13
Jason L Koh, Anthony L Logli
BACKGROUND: Standard knee arthroscopy portals are frequently used to address retropatellar chondral pathology. Alternative portals may offer a safe and simple substitute, particularly when reaching the base of deep lesions is required. PURPOSE: To describe and assess the safety of accessory retropatellar portals. STUDY DESIGN: Descriptive laboratory study. METHODS: An anatomic study was performed on 10 fresh-frozen cadaveric knees...
November 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/27884644/evaluating-augmentation-with-calcium-phosphate-cement-chronos-inject-for-bone-defects-after-internal-fixation-of-proximal-tibial-fractures-a-prospective-multicenter-observational-study
#14
C W Oh, K C Park, Y H Jo
INTRODUCTION: Managing subchondral bone defects in proximal tibia fractures after plateau reduction is an important consideration. ChronOS Inject is a recently developed calcium phosphate bone substitute that shows relatively fast osteointegration. HYPOTHESIS: Using chronOS Inject during internal fixation of proximal tibial fractures provides a satisfactory treatment option that is both clinically and radiologically safe. PATIENTS AND METHODS: Patients enrolled in this study were treated with chronOS Inject bone void filler, during internal fixation of proximal tibial fractures...
November 21, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27856067/posterior-cruciate-ligament-retention-or-substitution-during-total-knee-arthroplasty-does-not-affect-long-term-bone-mineral-density-or-quality
#15
Yoshinori Ishii, Hideo Noguchi, Junko Sato, Koji Todoroki, Shin-Ichi Toyabe
BACKGROUND: Physical activity is recognized as one of the factors that influence bone mineral density (BMD) and bone quality after total knee arthroplasty (TKA). According to biomechanical analyses after posterior cruciate ligament (PCL) retaining (PCLR) and substituting (PCLS) TKA, each implant design has different kinematics and kinetics. The purposes of this study were: (1) to perform within-patient comparisons of the midterm and long-term effects of PCL retention in mobile-bearing TKA on proximal femur and tibia BMD and calcaneus bone quality measured using ultrasound and (2) to identify correlations between them...
October 26, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27855716/kinematic-analysis-of-posterior-stabilized-total-knee-arthroplasty-during-standing-up-from-and-sitting-down-on-a-chair
#16
Takatomo Mine, Kenji Hoshi, Kazuyoshi Gamada, Koichiro Ihara, Hiroyuki Kawamura, Ryutaro Kuriyama, Ryo Date
BACKGROUND: Total knee arthroplasty is effective to regain quality of life. Standing up from and sitting down on a chair and stair stepping motion are important in daily living. We previously reported in vivo kinematics of this implant during a stepping exercise. The purpose of this analysis was to assess in vivo knee motion during standing up from and sitting down on a chair and determine the motion pattern in patients with the unique knee prosthesis. METHODS: A total of 15 patients implanted with Bi-Surface PS were assessed during standing up from and sitting down on a chair...
November 17, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27846352/-risk-factors-and-frequency-in-re-ruptures-of-the-anterior-cruciate-ligament-in-adults
#17
M L Velázquez-Rueda, J P Martínez-Ávila, A G Pérez-Serna, F Gómez-García
BACKGROUND: The anterior cruciate ligament (ACL) takes part in the knees articular cinematic regulation, which is why its rupture should be repaired as soon as possible. The surgical treatment is targeted to substitute the ruptured ACL with a graft that recreates the anatomical and biomechanical functions. Nevertheless, there are different factors that may produce a second rupture. OBJECTIVE: To determine the risk factors and frequency of failure in the ACL reconstruction...
March 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/27837219/acl-substitution-may-improve-kinematics-of-pcl-retaining-total-knee-arthroplasty
#18
Thomas Zumbrunn, Michael P Duffy, Harry E Rubash, Henrik Malchau, Orhun K Muratoglu, Kartik Mangudi Varadarajan
PURPOSE: One of the key factors responsible for altered kinematics and joint stability following contemporary total knee arthroplasty (TKA) is resection of the anterior cruciate ligament (ACL). However, ACL retention can present several technical challenges, and in some cases may not be viable due to an absent or nonfunctional ACL. Therefore, the goal of this research was to investigate whether substitution of the ACL through an anterior post mechanism could improve kinematic deficits of contemporary posterior cruciate ligament (PCL) retaining implants...
November 11, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27837209/-operative-treatment-in-orthopedics-and-trauma-surgery-are-more-operations-carried-out-in-germany
#19
P Garcia, C Domnick, G Lodde, M J Raschke
BACKGROUND: Since 2005, when the Diagnosis-Related Group (DRG) system was introduced, an increasing number of surgical procedures have been reported in Germany. In particular, the numbers of elective arthroplasty and spinal surgery procedures have been controversial. OBJECTIVES: The focus of this study was analyzing the development of spinal surgery, arthroplasty, and fracture management. MATERIALS AND METHODS: We analyzed the database for all musculoskeletal operating procedure codes (OPS codes 5‑78 to 5‑86) from 2005 to 2013 collected by the German Federal Statistical Office...
November 11, 2016: Der Unfallchirurg
https://www.readbyqxmd.com/read/27757780/comparison-of-osteoconductivity-and-absorbability-of-beta-tricalcium-phosphate-and-hydroxyapatite-in-clinical-scenario-of-opening-wedge-high-tibial-osteotomy
#20
Kwang-Jun Oh, Young-Bong Ko, Sagar Jaiswal, In-Cheul Whang
The purpose of this study was to compare the osteoconductivity, and absorbability of hydroxyapatite or beta-tricalcium phosphate in clinical scenario of opening wedge high tibial osteotomy Total 41 knees of 40 patients with follow up period of more than 1 year were enrolled. These patients were divided into two groups, Group I (22 knees, 21 patients) used hydroxyapatite and Group II (19 knees, 19 patients) used beta-tricalcium phosphate as a substitute in the opening gap. According to proven method, the osteoconductivity was assessed radiographically by the extent of new bone formation at osteotomy space and absorbability was evaluated by measuring the area occupied by substitute at immediate postoperative, postoperative 6 months and 1 year...
December 2016: Journal of Materials Science. Materials in Medicine
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