Samrat Ray, Anila Yousuf, Atit Dharia, Ghassan Ayoub, Catherine Parmentier, Andrea Norgate, Jeffrey Schiff, Chaya Shwaartz, Markus Selzner, Trevor W Reichman
UNLABELLED: Despite having emerged as a definitive treatment for diabetes mellitus (DM), pancreas transplantation remains a formidable surgical task owing to complications like graft pancreatitis, enteric leaks, and rejection. This becomes more challenging in the setting of underlying bowel pathology, such as inflammatory bowel disease (IBD), which has a strong immune-genomic association of co-existence with DM. Risk of anastomotic leaks, dose adjustments of immunosuppressants and biologicals, and management of IBD flares constitute some of the major perioperative challenges calling for a protocol-based, systematic, multidisciplinary approach...
April 2023: Annals of Medicine and Surgery