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subarachnoid hemorrhage 

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https://www.readbyqxmd.com/read/29660038/external-ventricular-drain-and-hemorrhage-in-aneurysmal-subarachnoid-hemorrhage-patients-on-dual-antiplatelet-therapy-a-retrospective-cohort-study
#1
Joseph S Hudson, Benjamin S Prout, Yasunori Nagahama, Daichi Nakagawa, Waldo R Guerrero, Mario Zanaty, Nohra Chalouhi, Pascal Jabbour, Sudeepta Dandapat, Lauren Allan, Santiago Ortega-Gutierrez, Edgar A Samaniego, David Hasan
BACKGROUND: Stenting and flow diversion for aneurysmal sub arachnoid hemorrhage (aSAH) require the use of dual antiplatelet therapy (DAPT). OBJECTIVE: To investigate whether DAPT is associated with hemorrhagic complication following placement of external ventricular drains (EVD) in patients with aSAH. METHODS: Rates of radiographically identified hemorrhage associated with EVD placement were compared between patients who received DAPT for stenting or flow diversion, and patients who underwent microsurgical clipping or coiling and did not receive DAPT by way of a backward stepwise multivariate analysis...
April 11, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29659999/increased-body-mass-index-associated-with-reduced-risk-of-delayed-cerebral-ischemia-and-subsequent-infarction-after-aneurysmal-subarachnoid-hemorrhage
#2
Lorenzo Rinaldo, Alejandro A Rabinstein, Giuseppe Lanzino
BACKGROUND: Increased body mass index (BMI) may be protective against cerebral ischemia in certain clinical contexts. OBJECTIVE: To investigate whether increased BMI was associated with delayed cerebral ischemia (DCI) and subsequent infarction after aneurysmal subarachnoid hemorrhage (aSAH). METHODS: We retrospectively reviewed the clinical course of patients presenting to our institution for management of aSAH. Patient were segregated according to BMI< or ≥29...
April 4, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29659050/continuous-electroencephalography-predicts-delayed-cerebral-ischemia-after-subarachnoid-hemorrhage-a-prospective-study-of-diagnostic-accuracy
#3
Eric S Rosenthal, Siddharth Biswal, Sahar F Zafar, Kathryn L O'Connor, Sophia Bechek, Apeksha V Shenoy, Emily J Boyle, Mouhsin M Shafi, Emily J Gilmore, Brandon P Foreman, Nicolas Gaspard, Thabele M Leslie-Mazwi, Jonathan Rosand, Daniel B Hoch, Cenk Ayata, Sydney S Cash, Andrew J Cole, Aman B Patel, M Brandon Westover
OBJECTIVE: Delayed cerebral ischemia (DCI) is a common, disabling complication of subarachnoid hemorrhage (SAH). Preventing DCI is a key focus of neurocritical care, but interventions carry risk and cannot be applied indiscriminately. While retrospective studies have identified continuous EEG (cEEG) measures associated with DCI, no study has characterized the accuracy of cEEG with sufficient rigor to justify using it to triage patients to interventions or clinical trials. We therefore prospectively assessed the accuracy of cEEG for predicting DCI, following the Standards for Reporting Diagnostic Accuracy Studies...
April 16, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29656002/dangers-of-outpatient-nimodipine-use-after-spontaneous-subarachnoid-hemorrhage-in-accordance-with-the-comprehensive-stroke-center-guidelines
#4
Ching-Jen Chen, Cassie Turnage, Jennifer D Sokolowski, Jeyan S Kumar, M Yashar Kalani, Min S Park
Despite the adverse effects and unclear benefit of the complete 21-day course of nimodipine therapy, The Joint Commission mandates adherence to nimodipine treatment for 21 days after hemorrhage or after hospital discharge if discharged within 21 days for Comprehensive Stroke Center (CSC) certification. We hereby present a 67 year-old male patient with Hunt-Hess grade 2 and Fisher grade 3 non-aneurysmal spontaneous subarachnoid hemorrhage who was discharged with oral nimodipine as stipulated by the CSC guidelines, and subsequently developed symptomatic hypotension...
April 11, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29652714/growing-evidence-dysautoregulation-may-trigger-ischemic-deficit-after-subarachnoid-hemorrhage
#5
Karol P Budohoski, Marek Czosnyka
No abstract text is available yet for this article.
May 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29652228/prediction-of-clinical-outcome-in-subacute-subarachnoid-hemorrhage-using-diffusion-tensor-imaging
#6
Isabel Fragata, Marta Alves, Ana Luísa Papoila, Patrícia Ferreira, Ana Paiva Nunes, Nuno Canto Moreira, Patrícia Canhão
OBJECTIVE Clinical outcome in nontraumatic subarachnoid hemorrhage (SAH) is multifactorial and difficult to predict. Diffusion tensor imaging (DTI) findings are a prognostic marker in some diseases such as traumatic brain injury. The authors hypothesized that DTI parameters measured in the subacute phase of SAH can be associated with a poor clinical outcome. METHODS Diffusion tensor imaging was prospectively performed in 54 patients at 8-10 days after nontraumatic SAH. Logistic regression analysis was performed to evaluate the association of fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values with a poor clinical outcome (modified Rankin Scale score ≥ 3) at 3 months...
April 13, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29651951/inflammatory-events-following-subarachnoid-hemorrhage-sah
#7
U C Schneider, R Xu, P Vajkoczy
Acute SAH from a ruptured intracranial aneurysm contributes for 30% of all hemorrhagic strokes. The bleeding itself occurs in the subarachnoid space. Nevertheless, injury to the brain parenchyma occurs as a consequence of the bleeding, directly, via several well-defined mechanisms and pathways, but also indirectly, or secondarily. This secondary brain injury following SAH has a variety of causes and possible mechanisms. Amongst others, inflammatory events have been shown to occur in parallel to, to contribute to, or even to initiate programmed cell death (PCD) within the central nervous system (CNS) in human and animal studies alike...
April 11, 2018: Current Neuropharmacology
https://www.readbyqxmd.com/read/29650786/association-of-quantified-location-specific-blood-volumes-with-delayed-cerebral-ischemia-after-aneurysmal-subarachnoid-hemorrhage
#8
W E van der Steen, I A Zijlstra, D Verbaan, A M M Boers, C S Gathier, R van den Berg, G J E Rinkel, B A Coert, Y B W E M Roos, C B L M Majoie, H A Marquering
BACKGROUND AND PURPOSE: Delayed cerebral ischemia is a severe complication of aneurysmal SAH and is associated with a high case morbidity and fatality. The total blood volume and the presence of intraventricular blood on CT after aneurysmal SAH are associated with delayed cerebral ischemia. Whether quantified location-specific (cisternal, intraventricular, parenchymal, and subdural) blood volumes are associated with delayed cerebral ischemia has been infrequently researched. This study aimed to associate quantified location-specific blood volumes with delayed cerebral ischemia...
April 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29649653/a-label-free-cellulose-sers-biosensor-chip-with-improvement-of-nanoparticle-enhanced-lspr-effects-for-early-diagnosis-of-subarachnoid-hemorrhage-induced-complications
#9
Wansun Kim, Sung Ho Lee, Yong Jin Ahn, Seung Ho Lee, Jiwook Ryu, Seok Keun Choi, Samjin Choi
It is very difficult to predict some complications after subarachnoid hemorrhage (SAH), despite rapid advances in medical science. Herein, we introduce a label-free cellulose surface-enhanced Raman spectroscopy (SERS) biosensor chip with pH-functionalized, gold nanoparticle (AuNP)-enhanced localized surface plasmon resonance (LSPR) effects for identification of SAH-induced cerebral vasospasm and hydrocephalus caused by cerebrospinal fluid (CSF). The SERS biosensor chip was implemented by the synthesis reaction of the AuNPs, which were charged positively through pH level adjustment, onto a negatively-charged cellulose substrate with ξ = -30...
April 4, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29649648/ultra-early-treatment-for-poor-grade-aneurysmal-subarachnoid-hemorrhage-a-systematic-review-and-meta-analysis
#10
Yangyun Han, Feng Ye, Xiaodong Long, Aiguo Li, Hong Xu, Linbo Zou, Yumin Yang, Md Chao You
OBJECTIVE: It remains unknown if ultra-early (within 24 hours after SAH onset) treatment could improve prognosis in poor-grade aneurysmal subarachnoid hemorrhage (aSAH). We aimed to evaluate the effect of ultra-early treatment on the functional outcome and mortality in poor-grade aSAH patients via systematic review and meta-analysis. METHODS: We performed a literature search in PubMed, MEDLINE and Web of Science databases. Primary outcomes were death and functional outcome assessed at any time period...
April 9, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29649643/estimating-the-global-incidence-of-aneurysmal-subarachnoid-hemorrhage-a-systematic-review-for-central-nervous-system-vascular-lesions-and-meta-analysis-of-ruptured-aneurysms
#11
REVIEW
Joshua D Hughes, Kamila M Bond, Rania A Mekary, Michael C Dewan, Abbas Rattani, Ronnie Baticulon, Yoko Kato, Hildo Azevedo-Filho, Jacques J Morcos, Kee B Park
INTRODUCTION: There is increasing acknowledgement that surgical care is important in global health initiatives. In particular, neurosurgical care is as limited as 1-to-10 million people in parts of the world. We performed a systematic literature review to examine the worldwide incidence of central nervous system vascular lesions (CNS-VL) and a meta-analysis of aneurysmal subarachnoid hemorrhage (ASAH) in order to define the disease burden and inform neurosurgical global health efforts...
April 9, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29628949/safety-of-diagnostic-cerebral-and-spinal-digital-subtraction-angiography-in-a-developing-country-a-single-center-experience
#12
Qasim Bashir, Asim Ishfaq, Ammad Anwar Baig
Background: Digital subtraction angiography (DSA) remains the gold standard imaging modality for cerebrovascular disorders. In contrast to developed countries, the safety of the procedure is not extensively reported from the developing countries. Herein, we present a retrospective analysis of the basic technique, indications, and outcomes in 286 patients undergoing diagnostic cerebral and spinal angiography in a developing country, Pakistan. Methods: A retrospective review of patient demographics, procedural technique and complication rates of 286 consecutive patients undergoing the diagnostic cerebral/spinal angiography procedure at one institution from May 2013 to December 2015 was performed...
February 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29628946/a-prospective-multicenter-trial-of-the-transform-occlusion-balloon-catheter-trial-design-and-results
#13
M Asif Taqi, Syed A Quadri, Ajit S Puri, Brian F Fitzsimmons, Jianhua Nancy Jin, Ansaar T Rai, Curtis A Given, Javier Masso, Ciaran J Powers, Joey D English, Osama O Zaidat
Background and Purpose: Adjunctive treatments like balloon-assisted coil embolization (BACE) and stent-assisted coil embolization play a major role in the treatment of wide-neck and large intracranial aneurysms. The TransForm™ Occlusion Balloon Catheter (TOBC) registry is intended to evaluate the safety, efficacy, and efficiency of BACE using the TOBC. Method and Study Design: The TOBC registry is a prospective multicenter registry trial. Seven sites in the USA and 1 site in Spain participated and enrolled 81 patients...
February 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29628945/balloon-assisted-cannulation-for-difficult-anterior-cerebral-artery-access
#14
Varun Naragum, Mohamad AbdalKader, Thanh N Nguyen, Alexander Norbash
The anterior communicating artery is a common location for intracranial aneurysms. Compared to surgical clipping, endovascular coiling has been shown to improve outcomes for patients with ruptured aneurysms and we have seen a paradigm shift favoring this technique for treating aneurysms. Access to the anterior cerebral artery can be challenging, especially in patients with tortuous anatomy or subarachnoid hemorrhage or in patients presenting with vasospasm. We present a technique for cannulating the anterior cerebral artery using a balloon inflated in the proximal middle cerebral artery as a rebound surface...
February 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29628943/provocative-testing-prior-to-anterior-cerebral-artery-fusiform-aneurysm-embolization
#15
Pouria Moshayedi, Dan-Victor Giurgiutiu, Andrew F Ducruet, Brian T Jankowitz, Ashutosh P Jadhav
We report 2 cases of parent artery occlusion (PAO) for anterior cerebral artery (ACA) fusiform aneurysm embolization after superselective provocative testing was performed to confirm distal territory viability. The first case involves a patient in the second decade of life who presented with subarachnoid hemorrhage and underwent PAO after a balloon test occlusion in the distal ACA revealed no neurophysiology changes. The second case involves another patient in the forth decade of life who presented with an enlarging pseudoaneurysm and underwent PAO after a sodium amobarbital infusion in the distal ACA revealed no clinical change...
February 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29627796/ruptured-aneurysm-of-the-artery-of-adamkiewicz-is-conservative-management-the-standard-of-treatment-in-the-current-era
#16
Pedro Aguilar-Salinas, Jussie Lima, Leonardo B C Brasiliense, Ricardo A Hanel, Eric Sauvageau
Spinal aneurysms are rare lesions, and their natural history is not well known. In particular, aneurysms arising from the artery of Adamkiewicz (AA) are an extremely rare phenomenon, and given the lack of solid evidence its management remains unclear. We present the case of a 54-year-old woman with spinal subarachnoid hemorrhage. A spinal angiogram demonstrated a fusiform aneurysm arising from the AA. Based on the location, the absence of evident collateral circulation to the anterior spinal artery, and the available literature supporting spontaneous thrombosis, we opted for conservative management...
April 7, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29627628/early-administration-of-hypertonic-hyperoncotic-hydroxyethyl-starch-hyperhes-improves-cerebral-blood-flow-and-outcome-after-experimental-subarachnoid-hemorrhage-in-rats
#17
Nadine Lilla, Christoph Rinne, Judith Weiland, Thomas Linsenmann, Thomas Westermaier
OBJECTIVE: Early cytotoxic brain edema may be one decisive factor which maintains a vicious of cerebral malperfusion after subarachnoid hemorrhage (SAH). In addition, endothelial cell swelling may be an independent factor restricting cerebral blood flow (CBF) in a very early stage after SAH. Immediate and aggressive treatment may be able to restore CBF in this critical period. MATERIALS AND METHODS: Male Sprague-Dawley rats were subjected to SAH by the endovascular filament model and treated by a bolus of hyperoncotic-hypertonic hydroxyethyl starch (HyperHES 4 ml/kg body weight) immediately after vessel perforation and 150 min later (n = 12) or by the same amount of normal saline (n = 9)...
April 5, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29626682/patterns-predictors-and-outcomes-of-post-procedure-delayed-hemorrhage-following-flow-diversion-for-intracranial-aneurysm-treatment
#18
A C White, D A Kumpe, C D Roark, D E Case, J Seinfeld
PURPOSE: To evaluate patterns, predictors, and outcomes of post procedure delayed hemorrhage (PPDH) following flow diversion therapy for intracranial aneurysm. METHODS: 50 patients with 52 aneurysms were treated from 2012-2016 with the Pipeline Embolization Device (PED; Medtronic, Minneapolis, MN). PED placement was performed as a standalone therapy or with adjunctive coil embolization. Patients underwent dual antiplatelet therapy (DAT) for 6 months following treatment...
April 4, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29626133/long-term-risk-of-hemorrhagic-stroke-in-young-patients-with-congenital-heart-disease
#19
Kok Wai Giang, Zacharias Mandalenakis, Mikael Dellborg, Georgios Lappas, Peter Eriksson, Per-Olof Hansson, Annika Rosengren
BACKGROUND AND PURPOSE: The risk of ischemic stroke is increased in patients with congenital heart disease (CHD); however, data on the risk of hemorrhagic stroke, including intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH), are lacking. METHODS: The Swedish Patient Register was used to identify all patients who were born with a diagnosis of CHD between 1970 and 1993. Each patient was compared with 10 randomly selected controls from the general population, matched for age, sex, and county...
April 6, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29625555/subarachnoid-hemorrhage-after-transient-global-amnesia-caused-by-cerebral-venous-congestion-case-report
#20
Yuta Maetani, Masahiro Nakamori, Tomoaki Watanabe, Hayato Matsushima, Eiji Imamura, Shinichi Wakabayashi
BACKGROUND: Transient global amnesia is reported to be caused by cerebral venous congestion. Internal jugular venous flow reversal in particular with the Valsalva maneuver leads to cerebral venous congestion. In addition, Valsalva maneuver can also induce subarachnoid hemorrhage. Transient global amnesia and subarachnoid hemorrhage might have common a pathophysiology in cerebral venous congestion. CASE PRESENTATION: We report here the case of a 57-year-old woman who twice experienced convexal subarachnoid hemorrhage just after straining at stool following an episode of transient global amnesia...
April 6, 2018: BMC Neurology
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