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subarachnoid hemorrhage 

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https://www.readbyqxmd.com/read/29908380/the-impact-of-extubation-failure-in-patients-with-good-grade-subarachnoid-hemorrhage
#1
Jann F Wojak, Claudia Ditz, Abdulkareem Abusamha, Emma Smith, Jan Gliemroth, Volker Tronnier, Jan Küchler
OBJECTIVE: The aim of this study was to analyze the clinical impact of extubation failure (EF) in with good grade subarachnoid hemorrhage (SAH), in which a good clinical course is usually expected. PATIENTS AND METHODS: We reviewed the clinical data from 141 patients with SAH and i. initial Hunt & Hess grade 1-3 ii. induction of general anesthesia for intervention and iii. the presence of data about the functional outcome. Patients were divided into three groups: 1...
June 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29907526/invasive-eeg-electrodes-in-presurgical-evaluation-of-epilepsies-systematic-analysis-of-implantation-video-eeg-monitoring-and-explantation-related-complications-and-review-of-literature
#2
Laurent M Willems, Philipp S Reif, Andrea Spyrantis, Adriano Cattani, Thomas M Freiman, Volker Seifert, Marlies Wagner, Se-Jong You, Susanne Schubert-Bast, Sebastian Bauer, Karl Martin Klein, Felix Rosenow, Adam Strzelczyk
INTRODUCTION: Stereoelectroencephalography (sEEG) is a diagnostic procedure for patients with refractory focal epilepsies that is performed to localize and define the epileptogenic zone. In contrast to grid electrodes, sEEG electrodes are implanted using minimal invasive operation techniques without large craniotomies. Previous studies provided good evidence that sEEG implantation is a safe and effective procedure; however, complications in asymptomatic patients after explantation may be underreported...
June 13, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29905889/thioredoxin-interacting-protein-mediates-mitochondrion-dependent-apoptosis-in-early-brain-injury-after-subarachnoid-hemorrhage
#3
Yidan Liang, Xudong Che, Qing Zhao, Rami Darwazeh, Hongxia Zhang, Dengzhi Jiang, Jun Zhao, Xiang Xiang, Wang Qin, Liu Liu, Zhaohui He
Early brain injury (EBI) was reported to be the primary cause of high mortality and poor outcomes in subarachnoid hemorrhage (SAH) patients, and apoptosis is regarded as the most important physiopathologic mechanism during EBI. Recently, our team found that thioredoxin-interacting protein (TXNIP) links endoplasmic reticulum stress (ER stress) to neuronal apoptosis and aggravates EBI. However, the other underlying mechanisms remain unknown. Mitochondria are considered to be the central points in integrating apoptotic cell death...
June 15, 2018: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/29904368/number-of-cigarettes-smoked-per-day-smoking-index-and-intracranial-aneurysm-rupture-a-case-control-study
#4
Xin Feng, Zenghui Qian, Baorui Zhang, Erkang Guo, Luyao Wang, Peng Liu, Xiaolong Wen, Wenjuan Xu, Chuhan Jiang, Youxiang Li, Zhongxue Wu, Aihua Liu
Background and purpose: We aimed to investigate the effect of smoking on the risk of intracranial aneurysm (IA) rupture (IAR), specifically relationship between the number of cigarettes smoked per day (CPD) or smoking index and the risk of IAR. Methods: We performed a single-center case-control study of consecutive patients evaluated or treated for IA at our institution from June 2015 to July 2016. Cases were patients with a ruptured IA. Two age- and sex-matched controls with an unruptured IA were included per case...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29904350/unique-contribution-of-haptoglobin-and-haptoglobin-genotype-in-aneurysmal-subarachnoid-hemorrhage
#5
REVIEW
Spiros L Blackburn, Peeyush T Kumar, Devin McBride, Hussein A Zeineddine, Jenna Leclerc, H Alex Choi, Pramod K Dash, James Grotta, Jaroslaw Aronowski, Jessica C Cardenas, Sylvain Doré
Survivors of cerebral aneurysm rupture are at risk for significant morbidity and neurological deficits. Much of this is related to the effects of blood in the subarachnoid space which induces an inflammatory cascade with numerous downstream consequences. Recent clinical trials have not been able to reduce the toxic effects of free hemoglobin or improve clinical outcome. One reason for this may be the inability to identify patients at high risk for neurologic decline. Recently, haptoglobin genotype has been identified as a pertinent factor in diabetes, sickle cell, and cardiovascular disease, with the Hp 2-2 genotype contributing to increased complications...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29902610/modified-extended-suboccipital-subtonsillar-clipping-of-a-ruptured-proximal-pica-aneurysm-technical-note-with-relevant-anatomical-demonstration
#6
Alberto Di Somma, Paloma Cancela, Magdalena Olivares, Teresa Somma, Antonio López-González, Alvaro Campero, Juan Emmerich, Javier Márquez-Rivas
BACKGROUND: and importance: Lesions located lateral to the lower brainstem, such as proximal posterior inferior cerebellar artery (PICA) aneurysms, are surgically challenging. In this study we report a case of a patient with a left proximal PICA aneurysm that was successfully clipped via a so-called "extended" suboccipital subtonsillar approach, which allowed to obtain proper vascular control without removal of the atlas. The anatomy relevant for this approach has been studied...
June 11, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29902601/study-of-correlation-between-hp-%C3%AE-1-expression-of-haptoglobin2-1-and-clinical-course-in-aneurysmal-subarachnoid-hemorrhage
#7
Bong Jun Kim, Youngmi Kim, Sung-Eun Kim, Jin Pyeong Jeon
OBJECTIVE: Haptoglobin (Hp) comprising two light (α) and two heavy (β) chains has an anti-oxidant effect following free hemoglobin binding. Among three phenotypes including Hp1-1 (two α1), Hp2-1 (α1 and α2), and Hp2-2 (two α2), a higher protective effect for toxic-free hemoglobin was reported for Hp2-2 than Hp1-1. However, few studies have focused on Hp2-1 in outcome. This study examined the α1 and α2 expression, and evaluated the correlation of Hp2-1 with subarachnoid hemorrhage (SAH) outcome...
June 11, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29895534/neurologic-outcome-predictors-in-pediatric-intracerebral-hemorrhage-a-prospective-study
#8
Giulia S Porcari, Lauren A Beslow, Rebecca N Ichord, Daniel J Licht, Jonathan T Kleinman, Lori C Jordan
BACKGROUND AND PURPOSE: Intracerebral hemorrhage is a considerable source of morbidity and mortality. This 3-center study describes outcomes of pediatric intracerebral hemorrhage and identifies 2-year neurological outcome predictors. METHODS: Children 29 days to 18 years of age presenting with intracerebral hemorrhage from March 2007 to May 2015 were enrolled prospectively. Exclusion criteria included trauma; intracranial tumor; hemorrhagic transformation of arterial ischemic stroke or cerebral sinovenous thrombosis; isolated subdural, epidural, or subarachnoid hemorrhage; and abnormal baseline neurological function...
June 12, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29892257/focused-neuro-otological-review-of-superficial-siderosis-of-the-central-nervous-system
#9
Aran Yoo, Jonathan Jou, Jeffrey D Klopfenstein, Jorge C Kattah
Background: Infratentorial siderosis (iSS) is a progressive degenerative disorder targeting primarily the cerebellum and cranial nerve eighth; therefore, progressive ataxia and its neuro-otological findings are common. Toxicity from hemosiderin involves selectively vulnerable neurons and glia in these posterior fossa structures. Other neurologic findings may be present, though our focus relates to the cochlea-vestibular cerebellar involvement. Radiographic evidence of siderosis may be the result of recurrent, albeit covert bleeding in the subarachnoid space, or the consequence of an overt post-traumatic or aneurysmal subarachnoid hemorrhage (SAH)...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29891122/a-non-traumatic-rapid-onset-headache-that-is-as-dangerous-as-subarachnoid-hemorrhage-sah-seen-in-the-emergency-department
#10
Matthew M Palilonis, Jeanne L Jacoby
No abstract text is available yet for this article.
May 30, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29890540/rehabilitation-after-clipping-of-cerebral-aneurysms-without-acute-subarachnoid-hemorrhage-outcome-analysis-of-100-consecutive-cases
#11
Andreas Jödicke, Karsten Bauer, Andrea Hajdukova
BACKGROUND:  Discharge to rehabilitation is reported in large studies as one important outcome parameter based on hospital codes. Because neurologic outcome scores (e.g., the modified Rankin Scale [mRS]) are missing in International Classification of Diseases (ICD) databases, rehabilitation indirectly serves as a kind of surrogate parameter for overall outcome. Reported fractions of patients with rehabilitation, however, largely differ between studies and seem high for patients with aneurysm clipping...
June 11, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29889274/posterior-reversible-encephalopathy-syndrome-as-a-complication-of-induced-hypertension-in-subarachnoid-hemorrhage-a-case-control-study
#12
Michelle L Allen, Tobias Kulik, Salah G Keyrouz, Rajat Dhar
BACKGROUND: Induced hypertension (IH) remains the mainstay of medical management for delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH). However, raising blood pressure above normal levels may be associated with systemic and neurological complications, of which posterior reversible encephalopathy syndrome (PRES) has been increasingly recognized. OBJECTIVE: To ascertain the frequency and predisposing factors for PRES during IH therapy. METHODS: We identified 68 patients treated with IH from 345 SAH patients over a 3-yr period...
June 8, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29889252/commentary-posterior-reversible-encephalopathy-syndrome-as-a-complication-of-induced-hypertension-in-subarachnoid-hemorrhage-a-case-control-study
#13
François Dépret, Maxime Coutrot
No abstract text is available yet for this article.
June 8, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29885663/aggf1-attenuates-neuroinflammation-and-bbb-disruption-via-pi3k-akt-nf-%C3%AE%C2%BAb-pathway-after-subarachnoid-hemorrhage-in-rats
#14
Qiquan Zhu, Budbazar Enkhjargal, Lei Huang, Tongyu Zhang, Chengmei Sun, Zhiyi Xie, Pei Wu, Jun Mo, Jiping Tang, Zongyi Xie, John H Zhang
BACKGROUND: Neuroinflammation and blood-brain barrier (BBB) disruption are two critical mechanisms of subarachnoid hemorrhage (SAH)-induced brain injury, which are closely related to patient prognosis. Recently, angiogenic factor with G-patch and FHA domain 1 (Aggf1) was shown to inhibit inflammatory effect and preserve vascular integrity in non-nervous system diseases. This study aimed to determine whether Aggf1 could attenuate neuroinflammation and preserve BBB integrity after experimental SAH, as well as the underlying mechanisms of its protective roles...
June 9, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29884521/nonaneurysmal-pseudo-subarachnoid-hemorrhage-computed-tomography-patterns-challenges-in-an-acute-decision-making-heuristics
#15
Tasneem F Hasan, Walter Duarte, Oluwaseun O Akinduro, Eric D Goldstein, Rebecca Hurst, Neil Haranhalli, David A Miller, Robert E Wharen, Rabih G Tawk, William D Freeman
BACKGROUND: Acute aneurysmal subarachnoid hemorrhage (SAH) is a medical and neurosurgical emergency from ruptured brain aneurysm. Aneurysmal SAH is identified on brain computed tomography (CT) as increased density of basal cisterns and subarachnoid spaces from acute blood products. Aneurysmal SAH-like pattern on CT appears as an optical illusion effect of hypodense brain parenchyma and/or hyperdense surrounding cerebral cisterns and blood vessels termed as "pseudo-subarachnoid hemorrhage" (pseudo-SAH)...
June 5, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29882706/risk-of-brain-herniation-after-craniotomy-with-lumbar-spinal-drainage-a-propensity-score-analysis
#16
Yasushi Motoyama, Tsukasa Nakajima, Yoshiaki Takamura, Tsutomu Nakazawa, Daisuke Wajima, Yasuhiro Takeshima, Ryosuke Matsuda, Kentaro Tamura, Shuichi Yamada, Hiroshi Yokota, Ichiro Nakagawa, Fumihiko Nishimura, Young-Su Park, Mitsutoshi Nakamura, Hiroyuki Nakase
OBJECTIVE Lumbar spinal drainage (LSD) during neurosurgery can have an important effect by facilitating a smooth procedure when needed. However, LSD is quite invasive, and the pathology of brain herniation associated with LSD has become known recently. The objective of this study was to determine the risk of postoperative brain herniation after craniotomy with LSD in neurosurgery overall. METHODS Included were 239 patients who underwent craniotomy with LSD for various types of neurological diseases between January 2007 and December 2016...
June 8, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29882700/clinical-prediction-of-delayed-cerebral-ischemia-in-aneurysmal-subarachnoid-hemorrhage
#17
Hubert Lee, Jeffrey J Perry, Shane W English, Fahad Alkherayf, Joanne Joseph, Steven Nobile, Linghong Linda Zhou, Howard Lesiuk, Richard Moulton, Charles Agbi, John Sinclair, Dar Dowlatshahi
OBJECTIVE The aim of this study was to derive a clinically applicable decision rule using clinical, radiological, and laboratory data to predict the development of delayed cerebral ischemia (DCI) in aneurysmal subarachnoid hemorrhage (aSAH) patients. METHODS Patients presenting over a consecutive 9-year period with subarachnoid hemorrhage (SAH) and at least 1 angiographically evident aneurysm were included. Variables significantly associated with DCI in univariate analysis underwent multivariable logistic regression...
June 8, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29882697/clipping-aneurysms-improves-outcomes-for-patients-undergoing-coiling
#18
Ian A Anderson, Ahilan Kailaya-Vasan, Richard J Nelson, Christos M Tolias
OBJECTIVE Most intracranial aneurysms are now treated by endovascular rather than by microsurgical procedures. There is evidence to demonstrate superior outcomes for patients with aneurysmal subarachnoid hemorrhage (aSAH) treated by endovascular techniques. However, some cases continue to require microsurgery. The authors have examined the relationship between the number of aneurysms treated by microsurgery and outcome for patients undergoing treatment for aSAH at neurosurgical centers in England. METHODS The Neurosurgical National Audit Programme (NNAP) database was used to identify aSAH cases and to provide associated 30-day mortality rates for each of the 24 neurosurgical centers in England...
June 8, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29880550/high-serum-level-of-matrix-metalloproteinase-7-is-associated-with-increased-risk-of-spontaneous-subarachnoid-hemorrhage
#19
Martin Söderholm, Gunilla Nordin Fredrikson, Jan Nilsson, Gunnar Engström
BACKGROUND AND PURPOSE: Increased degradation of the extracellular matrix in the arterial wall by matrix metalloproteinases (MMPs) may be an important mechanism in the pathogenesis of intracranial aneurysms and subarachnoid hemorrhage (SAH). MMP-2 and MMP-9 have been suggested to be involved in matrix degradation preceding SAH. We studied serum levels of MMP-1, -2, -3, -7, -9, -10, and -12 and the risk of incident SAH. METHODS: A nested case-control study within the population-based cohort, Malmö Diet and Cancer study, was performed including incident cases of spontaneous SAH (n=79) and controls matched by age, sex, and follow-up time (n=232)...
June 7, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29878164/commentary-outcome-after-clipping-and-coiling-for-aneurysmal-subarachnoid-hemorrhage-in-clinical-practice-in-europe-usa-and-australia
#20
Ethan A Winkler, W Caleb Rutledge, Adib A Abla
No abstract text is available yet for this article.
June 7, 2018: Neurosurgery
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