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https://www.readbyqxmd.com/read/28800856/-impact-of-mitral-annuloplasty-combined-with-surgical-revascularization-in-ischemic-mitral-regurgitation
#1
M Tribak, M Konaté, B Ould Hbib, P Konan, L Mahfoudi, A El Hassani, A Daouda, F Lachhab, N Bendagha, A Soufiani, J Fila, S Maghraoui, A Bensouda, L Marmade, S Moughil
INTRODUCTION: Ischemic Mitral Regurgitation (IMR) is a serious complication of coronary artery disease and is associated with a poor prognosis. The optimal surgical treatment of IMR involves controversies in its indications and modalities. OBJECTIVES: To determine whether mitral annuloplasty associated with surgical revascularization improved short and mid terms outcomes compared with revascularization alone in patients with IMR. METHODS: Between January 2007 and January 2011, 81 patients operated on Department of Cardiovascular Surgery "B" were included in this study divided into 3 groups...
August 8, 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/28800733/integrative-and-quantitive-evaluation-of-the-efficacy-of-his-bundle-related-pacing-in-comparison-with-conventional-right-ventricular-pacing-a-meta-analysis
#2
Ziqing Yu, Ruizhen Chen, Yangang Su, Xueying Chen, Shengmei Qin, Minghui Li, Fei Han, Junbo Ge
BACKGROUND: Long-term RVP could bring adverse problems to cardiac electro-mechanics and result in inter- and intra-ventricular asynchrony, impaired labor force, and aggravation of cardiac function. HBRP including direct His bundle pacing and para-His bundle pacing was regarded as a novel physiological pacing pattern to avoid devastating cardiac function. This synthetic study was conducted to integratively and quantitatively evaluate the efficacy of His bundle related pacing (HBRP) in comparison with conventional right ventricular pacing (RVP)...
August 11, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28799521/transcatheter-mitral-valve-replacement-long-term-outcomes-of-first-in-man-experience-with-an-apically-tethered-device-a-case-series-from-a-single-centre
#3
Alison Duncan, Anan Daqa, James Yeh, Simon Davies, Anselm Uebing, Cesare Quarto, Neil Moat
AIMS: Transcatheter mitral valve replacement (TMVR) is a novel technique for treating mitral regurgitation. We report 18-month/2-year outcomes of the 5 first-in-man patients undergoing chronic TMVR with the Tendyne device. METHODS AND RESULTS: Five patients (STS score 14%-23%) underwent TMVR using a Tendyne system under compassionate use at a single centre. 1 patient (who was noncompliant with anti-coagulation) died 9 months after TMVR following a cerebrovascular accident...
August 13, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28795446/tricuspid-valve-replacement-with-mechanical-prostheses-short-and-long-term-outcomes
#4
Xavier Rossello, Christian Muñoz-Guijosa, Elisabet Mena, Marta Camprecios, Ana B Mendez, Xavier Borras, Josep M Padro
BACKGROUND AND AIM: Tricuspid valve replacement has been associated with high mortality and poor long-term outcomes. We report the preoperative risk factors associated with short and long-term outcomes following tricuspid valve replacement with mechanical prostheses. METHODS: In 62 patients who underwent mechanical tricuspid valve replacement, clinical, laboratory, and echocardiographic findings were analyzed using both univariate and multivariate analyses to describe operative and long-term mortality...
August 9, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28790250/-usefulness-of-balloon-aortic-valvuloplasty-for-determining-the-operative-procedure-in-a-patient-with-severe-aortic-stenosis-complicated-with-secondary-mitral-regurgitation-report-of-a-case
#5
Kenichi Kamiya, Akira Furuta, Ryoi Okano, Haruki Tanaka, Masaomi Fukusumi, Tadamasa Miyauchi, Takeo Tedoriya
A 59-year-old man on chronic hemodialysis presented with severe aortic stenosis(AS) and moderate mitral regurgitation (MR). Although aortic valve replacement was scheduled, his status deteriorated into New York Heart Association(NYHA) class III heart failure due to the exacerbation of AS and concomitant MR. Double valve replacement was considered to be too high risk for the patient, and balloon aortic valvuloplasty(BAV) was initially performed. As a result, the mean pressure gradient of the aortic valve decreased from 65 to 28 mmHg and the mean pulmonary pressure also from 52 to 33 mmHg...
August 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28780580/net-atrioventricular-compliance-is-an-independent-predictor-of-cardiovascular-death-in-mitral-stenosis
#6
Maria Carmo Pereira Nunes, Timothy C Tan, Sammy Elmariah, Lucas Lodi-Junqueira, Bruno Ramos Nascimento, Rodrigo do Lago, Jose Luiz Padilha da Silva, Rodrigo Citton Padilha Reis, Xin Zeng, Igor F Palacios, Judy Hung, Robert A Levine
OBJECTIVES: Rheumatic mitral stenosis (MS) is a progressive disease, and risk of death may persist despite relief of the obstruction. Net atrioventricular compliance (Cn) modulates the overall haemodynamic burden of the MS and may be useful in predicting cardiovascular death after percutaneous mitral valvuloplasty (PMV). METHODS: A total of 427 patients (mean age 50±16 years, 84% female) with severe MS undergoing PMV were enrolled. Doppler-derived Cn was estimated at baseline using a previously validated equation...
August 5, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28775050/risk-assessment-prognosis-and-guideline-implementation-in-pulmonary-arterial-hypertension
#7
Athénaïs Boucly, Jason Weatherald, Laurent Savale, Xavier Jaïs, Vincent Cottin, Grégoire Prevot, François Picard, Pascal de Groote, Mitja Jevnikar, Emmanuel Bergot, Ari Chaouat, Céline Chabanne, Arnaud Bourdin, Florence Parent, David Montani, Gérald Simonneau, Marc Humbert, Olivier Sitbon
Current European guidelines recommend periodic risk assessment for patients with pulmonary arterial hypertension (PAH). The aim of our study was to determine the association between the number of low-risk criteria achieved within 1 year of diagnosis and long-term prognosis.Incident patients with idiopathic, heritable and drug-induced PAH between 2006 and 2016 were analysed. The number of low-risk criteria present at diagnosis and at first re-evaluation were assessed: World Health Organization (WHO)/New York Heart Association (NYHA) functional class I or II, 6-min walking distance (6MWD) >440 m, right atrial pressure <8 mmHg and cardiac index ≥2...
August 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28772041/budget-impact-of-intravenous-iron-therapy-with-ferric-carboxymaltose-in-patients-with-chronic-heart-failure-and-iron-deficiency-in-germany
#8
Ulrike Theidel, Saku Väätäinen, Janne Martikainen, Erkki Soini, Thomas Hardt, Wolfram Doehner
AIMS: Treatment of iron deficiency (ID) in patients with heart failure (HF) with intravenous iron substitution [ferric carboxymaltose (FCM)] has previously shown significant improvements in exercise capacity, New York Heart Association (NYHA) functional class, quality of life, and reduction of hospitalization. The aim of this study was to estimate the budget impact of FCM treatment for patients with HF and ID. METHODS AND RESULTS: Individual patient data from four double-blind randomized controlled trials were pooled for this analysis...
August 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28769566/association-of-left-ventricular-ejection-fraction-with-contrast-induced-nephropathy-and-mortality-following-coronary-angiography-or-intervention-in-patients-with-heart-failure
#9
Kun Wang, Hua-Long Li, Wei-Jie Bei, Xiao-Sheng Guo, Shi-Qun Chen, Sheikh Mohammed Shariful Islam, Ji-Yan Chen, Yong Liu, Ning Tan
BACKGROUND: Left ventricular ejection fraction (LVEF) is the most widely used parameter to evaluate the cardiac function in patients with heart failure (HF). However, the association between LVEF and contrast-induced nephropathy (CIN) is still controversial. Therefore, the aim of this study is to evaluate the association of LVEF with CIN and long-term mortality following coronary angiography (CAG) or intervention in patients with HF. METHODS: We analyzed 1,647 patients with HF (New York Heart Association [NYHA] or Killip class >1) undergoing CAG or intervention, including 207 (12...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28767656/collagen-turnover-biomarkers-and-systemic-right-ventricle-remodeling-in-adults-with-previous-atrial-switch-procedure-for-transposition-of-the-great-arteries
#10
Magdalena Lipczyńska, Piotr Szymański, Magdalena Kumor, Anna Klisiewicz, Piotr Hoffman
BACKGROUND: Myocardial fibrosis is a potential pathophysiological mechanism leading to systemic right ventricular (SRV) deterioration. We hypothesize that circulating levels of collagen deposition markers are elevated in patients with SRV remodeling and this elevation may have a predictive value. METHODS: We prospectively evaluated 56 patients with D-TGA after the atrial switch procedure (mean age 25.6 ± 4.8, range 18-37 years; 67% males). Serum levels of procollagen type III amino-terminal propeptide (PIIINP), collagen type I carboxy-terminal telopeptide (CITP), procollagen type I N-terminal propeptide (PINP), matrix metalloproteinase (MMP 1, MMP 9) and a tissue inhibitor of matrix metalloproteinase (TIMP 1) and N-terminal pro-brain natriuretic peptide (NT-pro-BNP) were measured and compared with healthy controls...
2017: PloS One
https://www.readbyqxmd.com/read/28766084/comparison-of-the-eq-5d-3l-and-the-sf-6d-sf-12-contemporaneous-utility-scores-in-patients-with-cardiovascular-disease
#11
Sanjeewa Kularatna, Joshua Byrnes, Yih Kai Chan, Chantal F Ski, Melinda Carrington, David Thompson, Simon Stewart, Paul A Scuffham
PURPOSE: Multi-attribute utility instruments (MAUIs) are widely used to measure utility weights. This study sought to compare utility weights of two popular MAUIs, the EQ-5D-3L and the SF-6D, and inform researchers in the selection of generic MAUI for use with cardiovascular (CVD) patients. METHODS: Data were collected in the Young@Heart study, a randomised controlled trial of a nurse-led multidisciplinary home-based intervention compared to standard usual care...
August 1, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28764220/to-evaluate-the-change-in-brain-natriuretic-peptide-levels-in-outpatients-with-ischemic-cardiomyopathy-and-its-association-with-functional-capacity-a-pilot-study
#12
Amarapalli Jayachandra, Vivek Aggarwal
INTRODUCTION: Literature is sparse on the clinical correlation of six minute walk test (6MWT) and Brain Natriuretic Peptide (BNP) levels in ischemic Cardiomyopathy (Ischemic CMP) patients. New York Heart Association (NYHA) classification is most commonly used for functional assessment of Heart Failure (HF), which is very subjective. This limitation is overcome by 6MWT which has prognostic significance in addition to assessment of level of functional impairment. Serum BNP correlate with clinical severity of HF as assessed by NYHA class...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28763468/predictors-of-lung-function-test-severity-and-outcome-in-systemic-sclerosis-associated-interstitial-lung-disease
#13
Noémie Le Gouellec, Alain Duhamel, Thierry Perez, Anne-Lise Hachulla, Vincent Sobanski, Jean-Baptiste Faivre, Sandrine Morell-Dubois, Marc Lambert, Pierre-Yves Hatron, Eric Hachulla, Hélène Béhal, Regis Matran, David Launay, Martine Remy-Jardin
Systemic sclerosis-related interstitial lung disease (SSc-ILD) is the leading cause of death in SSc. In this study, we aimed to describe the baseline severity and evolution of forced vital capacity (FVC) and diffusing capacity for carbon monoxide (DLCO) in patients with SSc-ILD and to assess the baseline clinical, biological and high-resolution CT scan (HRCT) predictors of this evolution. Baseline and serial FVC and DLCO were collected in 75 SSc-ILD patients followed during 6.4±4.2 years (n = 557 individual data)...
2017: PloS One
https://www.readbyqxmd.com/read/28762935/-galectin-3-markers-of-oxidative-stress-and-renal-dysfunction-in-patients-with-chronic-heart-failure
#14
E A Medvedeva, I I Berezin, Y V Shchukin
OBJECTIVE: to determine levels of galectin-3, markers of renal dysfunction, and plasma oxidative stress; to assess their correlation in patients with chronic heart failure (CHF) of various severity. MATERIAL AND METHODS: We included in this study 157 CHF patients (with documented prior myocardial infarction. Patients were divided into 3 groups according to their NYHA functional class (group 1 - class II n=60, group 2 - class III n=52, group 3 - class IV n=45). All patients underwent clinical examination, echocardiography...
March 2017: Kardiologiia
https://www.readbyqxmd.com/read/28762934/-diagnostic-value-of-biochemical-markers-in-patients-with-chronic-heart-failure-with-reduced-borderline-and-preserved-left-ventricular-ejection-fraction
#15
E V Bazaeva, R P Myasnikov, V A Metelskaya, S A Boytsov
PURPOSE OF THE STUDY: The study of the diagnostic value of biochemical markers of myocardial stress and inflammation in chronic heart failure (CHF) with different values of the ejection fraction (EF) of the left ventricle (LV). MATERIAL AND METHODS: The cross-sectional study included 105 patients aged 24 to 84 years (mean 58+/-14 years) with stable chronic heart failure I-II NYHA functional class classification. The causes of CHF were ischemic heart disease (IHD) in 33% of patients and arterial hypertension (AH) - 67%...
March 2017: Kardiologiia
https://www.readbyqxmd.com/read/28760721/transcatheter-aortic-valve-implantation-versus-re-do-surgery-for-failing-surgical-aortic-bioprosthesis-a-multi-centre-propensity-score-analysis
#16
Marco Spaziano, Darren Mylotte, Pascal Thériault-Lauzier, Ole De Backer, Lars Søndergaard, Johan Bosmans, Nicolas Debry, Thomas Modine, Marco Barbanti, Corrado Tamburino, Jan-Malte Sinning, Eberhard Grube, Georg Nickenig, Fritz Mellert, Sabine Bleiziffer, Rüdiger Lange, Benoit de Varennes, Kevin Lachapelle, Giuseppe Martucci, Nicolo Piazza
AIMS: Transcatheter aortic valve implantation for a failing surgical bioprosthesis (TAV- in-SAV) has become an alternative for patients at high risk for redo surgical aortic valve replacement (redo-SAVR). Comparisons between these approaches are non-existent. This study aims to compare clinical and echocardiographic outcomes of patients undergoing TAV-in-SAV versus redo-SAVR after accounting for baseline differences by propensity score matching. METHODS AND RESULTS: Patients from 7 centres in Europe and Canada who had undergone either TAV- in-SAV (n=79) or redo-SAVR (n=126) were identified...
August 1, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28760468/experience-with-pericardiectomy-for-constrictive-pericarditis-over-eight-decades
#17
Takashi Murashita, Hartzell V Schaff, Richard C Daly, Jae K Oh, Joseph A Dearani, John M Stulak, Katherine S King, Kevin L Greason
BACKGROUND: The purpose of this study was to review the surgical outcomes of pericardiectomy for constrictive pericarditis and to examine risk factors for overall mortality in a contemporary period. METHODS: We reviewed all patients who underwent pericardiectomy for constriction from 1936 through 2013. The investigation included constrictive pericarditis cases confirmed intraoperatively, all other types of pericarditis were excluded; 1,071 pericardiectomies were performed in 1,066 individual patients...
July 28, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28754546/comparison-of-different-stem-cell-mobilization-regimen-in-al-amyloidosis-patients
#18
Katharina Lisenko, Patrick Wuchter, Marion Hansberg, Anja Mangatter, Axel Benner, Anthony D Ho, Hartmut Goldschmidt, Ute Hegenbart, Stefan Schönland
High-dose melphalan (HDM) and autologous blood stem cell transplantation (ABSCT) is an effective treatment for transplant-eligible patients with systemic light chain (AL) amyloidosis. Whereas most centers use granulocyte colony-stimulating factor (G-CSF) alone for mobilization of peripheral blood stem cells (PBSC), the application of mobilization chemotherapy might offer specific advantages. We retrospectively analyzed 110 patients with AL amyloidosis who underwent PBSC collection. Major eligibility criteria included age <70 years and cardiac insufficiency NYHA ≤III°...
July 25, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28751436/a-striking-image-of-spontaneous-echo-contrast-in-severe-mitral-stenosis-in-a-patient-with-good-inr-control
#19
Daniel A Jeffery, Guy Lloyd, Arjun K Ghosh
A 38 year old man was referred to our valve clinic for assessment. He had been diagnosed with untreated rheumatic mitral stenosis (MS) in 2009. He was diagnosed with atrial fibrillation in 2016 [on warfarin with good INR control]. Transthoracic echocardiography demonstrated severe MS. A large amount of spontaneous echo contrast (SEC) was noted in the severely dilated left atrium and a transoesophageal echocardiogram (TOE) was requested for further assessment of the MS (Image 1 and Videos 1-3). He was symptomatic with shortness of breath and reduced exercise tolerance consistent with NYHA class III-IV...
July 27, 2017: Echo Research and Practice
https://www.readbyqxmd.com/read/28748266/treatment-of-chronic-heart-failure-in-germany-a-retrospective-database-study
#20
Stefan Störk, Renate Handrock, Josephine Jacob, Jochen Walker, Frederico Calado, Raquel Lahoz, Stephan Hupfer, Sven Klebs
BACKGROUND: Adherence to treatment guidelines affects outcomes in patients with chronic heart failure (HF). We investigated patient pathways and treatment patterns for HF in Germany. METHODS: This retrospective study used anonymous healthcare claims data from the German Health Risk Institute on individuals with statutory health insurance. Patients with uninterrupted data from 1 January 2009 to 31 December 2013 or death (whichever occurred first), and ≥2 recorded HF-related diagnoses in 2011, were included...
July 26, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
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