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https://www.readbyqxmd.com/read/28723771/malignant-melanoma-misdiagnosed-as-diabetic-foot-ulcer-a-case-report
#1
Wei Gao, Dawei Chen, Xingwu Ran
RATIONALE: Acral lentiginous melanoma (AML) does not exhibit the classic signs of malignant melanoma. ALM is frequently misdiagnosed because of its unusual sites and atypical clinical morphologies, which lead to poor prognosis. PATIENT CONCERNS: A female patient aged 78 years was presented to our center with two ulcers on her right foot. Diabetic foot ulcer was considered as the primary diagnosis. The ulcers failed to improve after 2 weeks' therapy. DIAGNOSES: An incisional biopsy of the lesion revealed malignant melanoma...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28722354/risk-factors-for-amputation-in-patients-with-diabetic-foot-infection-a-prospective-study
#2
Serhat Uysal, Bilgin Arda, Meltem I Taşbakan, Şevki Çetinkalp, Ilgın Y Şimşir, Anıl M Öztürk, Ayşe Uysal, İlgen Ertam
There is a variety of diagnostic and therapeutic algorithms for diabetic foot infections (DFIs). Some of them are too difficult to be applied in routine clinical approach. In the routine clinical approach, it is necessary to find new risk factors and end up with a quick and easy assessment of DFIs. In this study, we aimed to evaluate the independent risk factors for osteomyelitis, amputation and major amputation in patients with DFI using standard scoring procedures. We prospectively studied 379 patients with DFI...
July 19, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28720235/self-efficacy-and-self-care-behaviours-among-adults-with-type-2-diabetes
#3
Melba Sheila D'Souza, Subrahmanya Nairy Karkada, Kader Parahoo, Ramesh Venkatesaperumal, Susan Achora, Arcalyd Rose R Cayaban
BACKGROUND: Type 2 Diabetes Mellitus (T2DM) has an impact on an individuals' health and is influenced by glycemic control. AIM: To examine the relationship between glycemic control, demographic and clinical factors on self-efficacy and self-care behaviours among adults with T2DM. DESIGN: A correlational, descriptive study was used. One hundred and forty Omani adults with T2DM were recruited from a public hospital. METHODS: Data on self-efficacy, self-care behaviours and glycemic control were collected between April and July 2016...
August 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/28718238/bacteriology-of-diabetic-foot-in-tertiary-care-hospital-frequency-antibiotic-susceptibility-and-risk-factors
#4
Syeda Sadia Amjad, Jamal Zafar, Nadia Shams
BACKGROUND: Diabetic foot being one of the frequent and disabling complications of diabetes. In view of widespread regional variation in causative organisms and antimicrobial susceptibility, the current study aimed to determine frequency of causative organisms, their antimicrobial susceptibility and associated risk factors. METHODS: This descriptive cross-sectional study was conducted in 6 months' duration at dept. of Medicine; PIMS Hospital Islamabad. Type 2 Diabetes mellitus patients with diabetic foot ulcer were enrolled after informed consent...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28716357/clinical-and-metabolic-response-to-flaxseed-oil-omega-3-fatty-acids-supplementation-in-patients-with-diabetic-foot-ulcer-a-randomized-double-blind-placebo-controlled-trial
#5
Zahra Soleimani, Fatemeh Hashemdokht, Fereshteh Bahmani, Mohsen Taghizadeh, Mohammad Reza Memarzadeh, Zatollah Asemi
BACKGROUND: Data on the effects of flaxseed oil omega-3 fatty acids supplementation on wound healing and metabolic status in subjects with diabetic foot ulcer (DFU) are scarce. OBJECTIVE: This study was conducted to evaluate the effects of flaxseed oil omega-3 fatty acids supplementation on wound healing and metabolic status in subjects with DFU. METHODS: The current randomized, double-blind, placebo-controlled trial was conducted among 60 subjects (aged 40-85years old) with grade 3 DFU...
June 28, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28716100/quality-of-life-and-clinical-radiological-long-term-results-after-implant-associated-infections-in-patients-with-ankle-fracture-a-retrospective-matched-pair-study
#6
Patrick Ziegler, Donat Schlemer, Ingo Flesch, Sonja Bahrs, Ulrich Stoeckle, Sebastian Werner, Christian Bahrs
BACKGROUND: Ankle fractures are frequently occurring injuries. Despite the relatively simple operative technique, patients often suffer from postoperative complications. Little is known about postoperative treatment of implant-associated infections of the ankle. Therefore, this study shows and evaluates a treatment algorithm in long- and short-term outcomes compared to infection-free patients. METHODS: Data from patients of over 20 years of a level 1 trauma center and university hospital was retrospectively analyzed including age, gender, comorbidities, smoking status, fracture classification, number of revisions, length of in-patient stay due to fracture and infection, and results of microbiological specimen with the length of antibiotic treatment...
July 17, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28715342/quantitative-evaluation-of-rehabilitation-effect-on-peripheral-circulation-of-diabetic-foot
#7
Yao-Kuang Huang, Chang-Cheng Chang, Pin-Xing Lin, Bor-Shyh Lin
Diabetics may encounter different foot problems, which easily lead to infection, ulcers, and increased risk of amputation due to nerve or vascular injury. In order to reduce the risk of amputation, Buerger's exercise is one of the frequently used rehabilitation to improve the blood circulation in the lower limbs. However, it is difficult to evaluate the rehabilitation efficiency of Buerger's exercise objectively. In this study, a novel non-invasively optical system was developed to non-invasively monitor the change of the foot blood circulation before and after long-term Buerger's exercise...
July 13, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28712679/the-molecular-biology-in-wound-healing-non-healing-wound
#8
REVIEW
Chun Qing
The development of molecular biology and other new biotechnologies helps us to recognize the wound healing and non-healing wound of skin in the past 30 years. This review mainly focuses on the molecular biology of many cytokines (including growth factors) and other molecular factors such as extracellular matrix (ECM) on wound healing. The molecular biology in cell movement such as epidermal cells in wound healing was also discussed. Moreover many common chronic wounds such as pressure ulcers, leg ulcers, diabetic foot wounds, venous stasis ulcers, etc...
June 30, 2017: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/28710243/external-revascularisation-for-pseudochronic-total-occlusion-of-the-dorsal-pedis-artery-due-to-foot-drop-with-severe-diabetes-mellitus
#9
Nakabayashi Keisuke, Matsui Akihiro, Hiroshi Ando, Minoru Shimizu
No abstract text is available yet for this article.
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28708747/footwear-and-insole-design-features-to-prevent-foot-ulceration-in-people-with-diabetes-a-systematic-review-protocol
#10
Richard Collings, Jennifer Freeman, Jos M Latour, Sam Glasser, Joanne Paton
The aim of this systematic review is to identify the key design features of footwear and insoles that are used to offload the plantar surface of the foot to prevent foot ulceration in adults with diabetes.More specifically, the objectives are to identify the key design features of footwear and insoles to offload the plantar surface of the foot with regard to.
July 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28707412/differences-in-the-daily-activity-of-patients-with-diabetic-foot-ulcers-compared-to-controls-in-their-free-living-environments
#11
Helen Sheahan, Kimberley Canning, Nishka Refausse, Ewan M Kinnear, Greg Jorgensen, James R Walsh, Peter A Lazzarini
The aims of our study were to investigate multiple daily activity outcomes in patients with diabetic foot ulcers (DFU) compared to diabetic peripheral neuropathy (DPN) and diabetes (DM) controls in their free-living environments. We examined daily activity outcomes of 30 patients with DFU, 23 DPN and 20 DM. All patients wore a validated multi-sensor device for > 5 days (>22 hours per day) to measure their daily activity outcomes: steps, energy expenditure (kJ), average metabolic equivalent tasks (METs), physical activity (>3·0 METs) duration and energy expenditure, lying duration, sleep duration and sleep quality...
July 13, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28706922/barriers-and-enablers-to-proper-diabetic-foot-care-amongst-community-dwellers-in-an-asian-population-a-qualitative-study
#12
Andrew Arjun Sayampanathan, Amit Nirmal Cuttilan, Christopher J Pearce
BACKGROUND: Diabetic foot complications are common within Asian populations. They arise due to poor diabetic control and foot care. In this study, we aimed to identify the causes for proper and improper diabetic foot care. METHODS: A qualitative study consisting of key informant interviews with 17 healthcare professionals, including doctors and various allied health workers, was conducted. Participants included had at least five years of caring for diabetic foot patients either in public institutions or private clinics...
June 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28704763/symptoms-of-anxiety-and-depression-in-type-2-diabetes-associations-with-clinical-diabetes-measures-and-self-management-outcomes-in-the-norwegian-hunt-study
#13
Kiyuri Naicker, Simon Øverland, Jeffrey A Johnson, Douglas Manuel, Jens C Skogen, Børge Sivertsen, Ian Colman
OBJECTIVE: To determine if symptoms of depression and anxiety are differentially associated with clinical diabetes measures and self-management behaviours in individuals with Type 2 diabetes, and whether these associations vary by patient sex. RESEARCH DESIGN AND METHODS: A cross-sectional analysis using data from 2035 adults with Type 2 diabetes in the Nord-Trøndelag Health Study. Multivariate logistic regression was used to explore associations between symptoms of depression and anxiety and waist girth, HDL cholesterol, systolic blood pressure, triglycerides, c-reactive protein, glycemic control, diet adherence, exercise, glucose monitoring, foot checks for ulcers, and the subjective patient experience...
July 6, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28704149/amputation-predictors-in-diabetic-foot-ulcers-treated-with-hyperbaric-oxygen
#14
S T Kaplan, D Hemsinli, S Kaplan, A Arslan
OBJECTIVE: Although hyperbaric oxygen therapy (HBOT) has long been used for diabetic foot ulcers (DFUs), its effectiveness is still controversial. The aim of this study was to investigate the efficacy of HBOT in the management of DFUs and identify amputation predictors. METHOD: Patients with chronic DFUs (Wanger grade 2-5) were included in the study, which took place between January 2010 and December 2012. HBOT, 100% oxygen, 2.4 atmosphere absolute (ATA) for 120 minutes, was administered to all patients in addition to standard treatment...
July 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28702256/physician-knowledge-of-a-rare-foot-condition-influence-of-diabetic-patient-population-on-self-described-knowledge-and-treatment
#15
Brian M Schmidt, James S Wrobel, Crystal M Holmes
BACKGROUND: Charcot neuroarthopathy (CN), a rare foot and ankle condition usually complicating diabetes mellitus, leads to deformity, poor quality of life, and increased mortality and morbidity. The prevalence of this condition in the diabetic patient population is not currently known but has been reportedly misdiagnosed in up to 95% of cases. METHODS: We sought to evaluate general knowledge regarding CN in non-foot specialist clinical faculty at a large academic institution and to understand their practice habits...
2017: Clinical Diabetes and Endocrinology
https://www.readbyqxmd.com/read/28699352/redox-signaling-in-diabetic-wound-healing-regulates-extracellular-matrix-deposition
#16
Britta Kunkemoeller, Themis Kyriakides
SIGNIFICANCE: Impaired wound healing is a major complication of diabetes, and can lead to development of chronic foot ulcers in a significant portion of patient. Despite the danger posed by poor healing, very few specific therapies exist, leaving patients at risk of hospitalization, amputation, and further decline in overall health. Recent Advances: Redox signaling is a key regulator of wound healing, especially through its influence on the extracellular matrix (ECM). Normal redox signaling is disrupted in diabetes leading to several pathological mechanisms that alter the balance between reactive oxygen species (ROS) generation and scavenging...
July 12, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28697694/midterm-outcomes-from-a-pilot-study-of-percutaneous-deep-vein-arterialization-for-the-treatment-of-no-option-critical-limb-ischemia
#17
Steven Kum, Yih Kai Tan, Michiel A Schreve, Roberto Ferraresi, Ramon L Varcoe, Andrej Schmidt, Dierk Scheinert, Jihad A Mustapha, Darryl M Lim, Derek Ho, Tjun Y Tang, Vlad-Adrian Alexandrescu, Pramook Mutirangura
PURPOSE: To report the initial clinical experience with percutaneous deep vein arterialization (PDVA) to treat critical limb ischemia (CLI) via the creation of an arteriovenous fistula. METHODS: Seven patients (median age 85 years; 5 women) with CLI and no traditional endovascular or surgical revascularization options (no-option CLI) were recruited in a pilot study to determine the safety of PDVA. All patients were diabetic; 4 had Rutherford category 6 ischemia...
July 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28696850/advanced-mr-imaging-techniques-for-differentiation-of-neuropathic-arthropathy-and-osteomyelitis-in-the-diabetic-foot
#18
Teodoro Martín Noguerol, Antonio Luna Alcalá, Luis S Beltrán, Marta Gómez Cabrera, Jordi Broncano Cabrero, Joan C Vilanova
Diagnosis and treatment of foot disease in patients with diabetes is a common clinical-radiologic challenge, particularly the differentiation of neuropathic arthropathy from osteomyelitis. Conventional clinical tests and imaging techniques have limited accuracy for evaluation of the diabetic foot. The introduction of morphologic magnetic resonance (MR) imaging in these patients has provided a qualitative leap in diagnosis. The characteristics of soft-tissue and bone marrow edema and their patterns of distribution throughout the foot allow discrimination between both entities...
July 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28696493/total-contact-cast-system-to-heal-diabetic-foot-ulcers
#19
Brock Liden
Off-loadinga diabetic foot ulcer is a cornerstone of quality wound care for diabetic patients to allow cellular growth in the wound bed. While total contact casts (TCC) have been described as the gold standard for off-loading the wound, the complexity of application and the time commitment for both application and drying have discouraged health professionals from using them. This retrospective case series, conducted in a podiatric practice, evaluated using a TCC system that helps address the three components in which guidelines should be addressed when caring for a diabetic foot: V - vascular management, I - infection management and prevention, and P - pressure relief...
July 11, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28696230/implications-of-antimicrobial-combinations-in-complex-wound-biofilms-containing-fungi
#20
Eleanor M Townsend, Leighann Sherry, Ryan Kean, Donald Hansom, William G Mackay, Craig Williams, John Butcher, Gordon Ramage
Diabetic foot ulcer treatment currently focuses on targeting bacterial biofilms, while dismissing fungi. To investigate this we used an in vitro biofilm model containing bacteria and fungi, reflective of the wound environment, to test the impact of antimicrobials. Here we showed that while mono-treatment approaches influenced biofilm composition it had no discernible effect on overall quantity. Only by combining bacterial and fungal specific antibiotics were we able to decrease the biofilm bioburden, irrespective of composition...
July 10, 2017: Antimicrobial Agents and Chemotherapy
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