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Glucomannan

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https://www.readbyqxmd.com/read/28429913/effect-of-glucomannan-on-functional-constipation-in-children-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#1
Yong Han, Lei Zhang, Xiang-Qun Liu, Zhi-Jun Zhao, Lu-Xian Lv
BACKGROUND AND OBJECTIVES: Constipation, a common complaint in children, considerably affects the quality of life. This systematic review assessed the treatment effects of glucomannan on children with constipation by summarising evidence from previous randomised controlled trials (RCTs). METHODS AND STUDY DESIGN: A comprehensive electronic literature search was conducted for identifying eligible RCTs that evaluated the effectiveness of glucomannan. The results were reported as mean differences (MDs), standardised mean differences (SMDs), and risk ratios (RRs) with 95% confidence intervals (CIs)...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28408313/preventing-cardiovascular-heart-disease-promising-nutraceutical-and-non-nutraceutical-treatments-for-cholesterol-management
#2
REVIEW
T P Johnston, T A Korolenko, M Pirro, A Sahebkar
Hypercholesterolemia is one of the major risk factors for the development of cardiovascular disease. Atherosclerosis resulting from hypercholesterolemia causes many serious cardiovascular diseases. Statins are generally accepted as a treatment of choice for lowering low-density lipoprotein (LDL) cholesterol, which reduces coronary heart disease morbidity and mortality. Since statin use can be associated with muscle problems and other adverse symptoms, non-adherence and discontinuation of statin therapy often leads to inadequate control of plasma cholesterol levels and increased cardiovascular risk...
April 10, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/28372193/effects-of-konjac-glucomannan-on-heat-induced-changes-of-wheat-gluten-structure
#3
Yu Wang, Yiheng Chen, Yun Zhou, Satoru Nirasawa, Eizo Tatsumi, Xiuting Li, Yongqiang Cheng
Effects of konjac glucomannan on the structure of wheat gluten were investigated at variable temperatures in this study. Dynamic oscillatory rheology study showed that konjac glucomannan conferred stiffness on gluten with a higher tan δ data at 25°C and 55°C, but this parameter was lower at 75°C and 95°C. Konjac glucomannan decreased the content of thiol equivalent groups and increased the α-helix/β-sheet content ratio, respectively. The thicker layer of gluten protein with 5% konjac glucomannan was observed by scanning electron microscopy...
August 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28363561/a-kinetic-model-of-the-gelation-of-konjac-glucomannan-induced-by-deacetylation
#4
Ching-Feng Mao, Cheng-Ho Chen
The gelation of konjac glucomannan (KGM) often involves an induction period featured by an initial drop in modulus. The gelation kinetics recorded as a time-dependent modulus change is composed of an initial drop followed by a steady increase in modulus until an equilibrium stage is reached. In this work, the time-dependent modulus curve is described by a kinetic model which incorporates the cascade theory with the kinetic equations consisting of sequential reactions of deacetylation and cross-link formation...
June 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28356275/a-systematic-review-and-meta-analysis-of-randomized-controlled-trials-of-the-effect-of-konjac-glucomannan-a-viscous-soluble-fiber-on-ldl-cholesterol-and-the-new-lipid-targets-non-hdl-cholesterol-and-apolipoprotein-b
#5
Hoang Vi Thanh Ho, Elena Jovanovski, Andreea Zurbau, Sonia Blanco Mejia, John L Sievenpiper, Fei Au-Yeung, Alexandra L Jenkins, Lea Duvnjak, Lawrence Leiter, Vladimir Vuksan
Background: Evidence from randomized controlled trials (RCTs) suggests the consumption of konjac glucomannan (KJM), a viscous soluble fiber, for improving LDL-cholesterol concentrations. It has also been suggested that the cholesterol-lowering potential of KJM may be greater than that of other fibers. However, trials have been relatively scarce and limited in sample size and duration, and the effect estimates have been inconsistent. The effect of KJM on new lipid targets of cardiovascular disease (CVD) risk is also unknown...
March 29, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28325998/glucomannan-and-glucomannan-plus-spirulina-enriched-pork-affect-liver-fatty-acid-profile-ldl-receptor-expression-and-antioxidant-status-in-zucker-fa-fa-rats-fed-atherogenic-diets
#6
Laura González-Torres, Cátia Matos, Miguel Vázquez-Velasco, Jorge A Santos-López, Iria Sánchez-Martínez, Camino García-Fernández, Sara Bastida, Juana Benedí, Francisco J Sánchez-Muniz
We evaluated the effects of glucomannan or glucomannan plus spirulina-restructured pork (RP) on liver fatty acid profile, desaturase/elongase enzyme activities and oxidative status of Zucker fa/fa rats for seven weeks. Control (C), glucomannan (G) and glucomannan/spirulina (GS)-RP; HC (cholesterol-enriched control), HG and HGS (cholesterol-enriched glucomannan and glucomannan/spirulina-RP) experimental diets were tested. Increased metabolic syndrome markers were found in C, G and GS rats. Cholesterol feeding increased liver size, fat, and cholesterol and reduced antioxidant enzyme levels and expressions...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28317006/proteomic-data-on-enzyme-secretion-and-activity-in-the-bacterium-chitinophaga-pinensis
#7
Johan Larsbrink, Tina R Tuveng, Phillip B Pope, Vincent Bulone, Vincent G H Eijsink, Harry Brumer, Lauren S McKee
The secretion of carbohydrate-degrading enzymes by a bacterium sourced from a softwood forest environment has been investigated by mass spectrometry. The findings are discussed in full in the research article "Proteomic insights into mannan degradation and protein secretion by the forest floor bacterium Chitinophaga pinensis" in Journal of Proteomics by Larsbrink et al. ([1], doi: 10.1016/j.jprot.2017.01.003). The bacterium was grown on three carbon sources (glucose, glucomannan, and galactomannan) which are likely to be nutrient sources or carbohydrate degradation products found in its natural habitat...
April 2017: Data in Brief
https://www.readbyqxmd.com/read/28293293/the-podospora-anserina-lytic-polysaccharide-monooxygenase-palpmo9h-catalyzes-oxidative-cleavage-of-diverse-plant-cell-wall-matrix-glycans
#8
Mathieu Fanuel, Sona Garajova, David Ropartz, Nicholas McGregor, Harry Brumer, Hélène Rogniaux, Jean-Guy Berrin
BACKGROUND: The enzymatic conversion of plant biomass has been recently revolutionized by the discovery of lytic polysaccharide monooxygenases (LPMO) that catalyze oxidative cleavage of polysaccharides. These powerful enzymes are secreted by a large number of fungal saprotrophs and are important components of commercial enzyme cocktails used for industrial biomass conversion. Among the 33 AA9 LPMOs encoded by the genome of Podospora anserina, the PaLPMO9H enzyme catalyzes mixed C1/C4 oxidative cleavage of cellulose and cello-oligosaccharides...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28265262/genomic-analysis-of-caldithrix-abyssi-the-thermophilic-anaerobic-bacterium-of-the-novel-bacterial-phylum-calditrichaeota
#9
Ilya V Kublanov, Olga M Sigalova, Sergey N Gavrilov, Alexander V Lebedinsky, Christian Rinke, Olga Kovaleva, Nikolai A Chernyh, Natalia Ivanova, Chris Daum, T B K Reddy, Hans-Peter Klenk, Stefan Spring, Markus Göker, Oleg N Reva, Margarita L Miroshnichenko, Nikos C Kyrpides, Tanja Woyke, Mikhail S Gelfand, Elizaveta A Bonch-Osmolovskaya
The genome of Caldithrix abyssi, the first cultivated representative of a phylum-level bacterial lineage, was sequenced within the framework of Genomic Encyclopedia of Bacteria and Archaea (GEBA) project. The genomic analysis revealed mechanisms allowing this anaerobic bacterium to ferment peptides or to implement nitrate reduction with acetate or molecular hydrogen as electron donors. The genome encoded five different [NiFe]- and [FeFe]-hydrogenases, one of which, group 1 [NiFe]-hydrogenase, is presumably involved in lithoheterotrophic growth, three other produce H2 during fermentation, and one is apparently bidirectional...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28248105/manufacture-and-properties-of-glucomannans-and-glucomannooligosaccharides-derived-from-konjac-and-other-sources
#10
Belén Gómez, Beatriz Míguez, Remedios Yáñez, José L Alonso
Glucomannans (GM) are polymers that can be found in natural resources, such as tubers, bulbs, roots, and both hard- and softwoods. In fact, mannan-based polysaccharides represent the largest hemicellulose fraction in softwoods. In addition to their structural functions and their role as energy reserve, they have been assessed for their healthy applications, including their role as new source of prebiotics. This paper summarizes the scientific literature regarding the manufacture and functional properties of GM and their hydrolysis products with a special focus on their prebiotic activity...
March 1, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28224918/remodeling-of-pectin-and-hemicelluloses-in-tomato-pericarp-during-fruit-growth
#11
Fabienne Guillon, Adeline Moïse, Bernard Quemener, Brigitte Bouchet, Marie-Françoise Devaux, Camille Alvarado, Marc Lahaye
Tomato fruit texture depends on histology and cell wall architecture, both under genetic and developmental controls. If ripening related cell wall modifications have been well documented with regard to softening, little is known about cell wall construction during early fruit development. Identification of key events and their kinetics with regard to tissue architecture and cell wall development can provide new insights on early phases of texture elaboration. In this study, changes in pectin and hemicellulose chemical characteristics and location were investigated in the pericarp tissue of tomato (Solanum lycopersicon var Levovil) at four stages of development (7, 14 and 21day after anthesis (DPA) and mature green stages)...
April 2017: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/28224899/impact-of-plant-matrix-polysaccharides-on-cellulose-produced-by-surface-tethered-cellulose-synthases
#12
Snehasish Basu, Okako Omadjela, Jochen Zimmer, Jeffrey M Catchmark
Surface immobilized BcsA-B cellulose synthases synthesize crystalline cellulose II under in vitro conditions and were used to explore the interaction between cellulose and hemicelluloses and pectin. The morphology of the cellulose microfibrils changed in the presence of xyloglucan and glucomannan, while pectin did not significantly impact morphology. X-ray diffractometry and FT-IR spectroscopy indicated that crystal size and crystallinity were significantly affected by xyloglucan and glucomannan but not altered by pectin...
April 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28224896/carboxylmethyl-konjac-glucomannan-conjugated-polydopamine-composites-for-pb-ii-removal
#13
Pan-Pan Chen, Hong-Ping Zhang, Jianping Ding, Xiao-Yan Lin, Xiong Lu, Changsheng Liu, Youhong Tang
Carboxylmethyl konjac glucomannan conjugated polydopamine (CMKGM-PDA) composite was successfully prepared using a cost-effective method. CMKGM-PDA exhibited excellent adsorption performance for the removal of Pb(II) and could be a convenient agent for recovery. The Langmuir linear model was suitable for describing the adsorption process of Pb(II). The maximum adsorption capacity was 95.24mgg(-1) at 298K, showing a high absorption capacity in comparison to similar absorbents. The pseudo-second order equation and intra-particle diffusion model exhibited good correlation with the adsorption kinetic...
April 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28220352/purification-characterization-and-overexpression-of-an-endo-1-4-%C3%AE-mannanase-from-thermotolerant-bacillus-sp-swu60
#14
Weeranuch Seesom, Polphet Thongket, Tomohiro Yamamoto, Shigeo Takenaka, Tatsuji Sakamoto, Wasana Sukhumsirichart
Endo-β-1,4-mannanases are important catalytic agents in several industries. The enzymes randomly cleave the β-1,4-linkage in the mannan backbone and release short β-1,4-mannooligosaccharides and mannose. In the present study, mannanase (ManS2) from thermotolerant Bacillus sp. SWU60 was purified, characterized, and its gene was cloned and overexpressed in Escherichia coli. ManS2 was purified from culture filtrate (300 ml) by using hydrophobic, ion-exchange, and size-exclusive liquid chromatography. The apparent molecular mass was 38 kDa...
March 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28193408/physicochemical-characterization-antioxidant-capacity-total-phenolic-and-proanthocyanidin-content-of-flours-prepared-from-pequi-caryocar-brasilense-camb-fruit-by-products
#15
Daniela P Leão, Adriana S Franca, Leandro S Oliveira, Rita Bastos, Manuel A Coimbra
The potential of pequi by-products as substrates for the production of flours rich in antioxidant dietary fibers was evaluated. Dietary fiber contents ranged from 39.8 to 43.3g/100g with pectic polysaccharide fraction constituted of rhamnogalacturonans and hemicellulose fraction consisted of arabinogalactans, xylans and glucomannans. Total polyphenols, non-extractable proanthocyanidins (NEPA) and carotenoid contents of the flours were determined (respectively, 15.5-17.4g GAE/100g, 215.54-346.84mg/100g and 2116...
June 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28180916/fermentation-of-model-hemicelluloses-by-prevotella-strains-and-butyrivibrio-fibrisolvens-in-pure-culture-and-in-ruminal-enrichment-cultures
#16
Elianna L Emerson, Paul J Weimer
Hemicelluloses are major components of plant biomass, but their fermentation in the rumens of cattle and other ruminants is poorly understood. We compared four species of the ruminally dominant genus Prevotella and the well-known hemicellulose utilizer, Butyrivibrio fibrisolvens, with respect to degradation of several isolated hemicelluloses (xylans, glucomannan, and xyloglucan). We also performed Illumina sequencing of the V3/V4 region of 16S rRNA genes to determine the relative proportions of Prevotella and Butyrivibrio in hemicellulose-fed enrichment cultures inoculated from ruminal contents of dairy cattle fed a total mixed ration (TMR) rich in hemicelluloses...
February 8, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28169529/deacetylated-konjac-glucomannan-is-less-effective-in-reducing-dietary-induced-hyperlipidemia-and-hepatic-steatosis-in-c57bl-6-mice
#17
Mei-Ying Li, Guan-Ping Feng, Hong Wang, Rui-Li Yang, Zhenlin Xu, Yuan-Ming Sun
Konjac gel foods that mainly consist of deacetylated konjac glucomannan (Da-KGM) are considered to have the same health benefits as native konjac glucomannan (KGM); however, no definitive data support this notion. The objective of this study was to compare the effects of Da-KGM and KGM on the hyperlipidemia and liver steatosis induced by high-fat diet feeding and to investigate the underlying molecular mechanisms. C57BL/6 mice were fed (1) normal chow diet, (2) high-fat diet, (3) HFD with KGM, or (4) HFD with Da-KGM for 10 weeks...
February 17, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28132504/gelatin-based-nanocomplex-stabilized-pickering-emulsions-regulating-droplet-size-and-wettability-through-assembly-with-glucomannan
#18
Weiping Jin, Jieyu Zhu, Yike Jiang, Ping Shao, Bin Li, Qingrong Huang
Particle size and surface wettability play leading roles in the distribution of particles on the oil-water interface and the stability of emulsions. This work utilized nanocomplexes assembled from gelatin and tannic acid to stabilize Pickering emulsions. The sizes and surface wettability of particles were further regulated by using a polysaccharide. The sizes of nanocomplexes ranged from 205.8 to 422.2 nm and increased with the addition of polysaccharide. Their contact angles decreased from 84.1° to 59.3°, revealing their hydrophilic nature...
February 10, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28130129/heparin-mimetic-polyurethane-hydrogels-with-anticoagulant-tunable-mechanical-property-and-controllable-drug-releasing-behavior
#19
Yuan Chen, Rui Wang, Yonghui Wang, Weifeng Zhao, Shudong Sun, Changsheng Zhao
In the present study, novel heparin-mimetic polyurethane hydrogels were prepared by introducing chemical crosslinked sulfated konjac glucomannan (SKGM). Scanning electron microscopy (SEM) results indicated that the introduction of SKGM and the increase of the molecular weight of diol segments could enlarge the pore sizes of the hydrogels. The swelling behavior corresponded with the SEM results, and the hydrogels could absorb more water after the modification. The modification also led to an improvement in the mechanical property...
January 24, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28106808/anti-fatigue-effects-of-the-unique-polysaccharide-marker-of-dendrobium-officinale-on-balb-c-mice
#20
Wei Wei, Zhi-Peng Li, Tong Zhu, Hau-Yee Fung, Tin-Long Wong, Xin Wen, Dik-Lung Ma, Chung-Hang Leung, Quan-Bin Han
Dendrobium officinale extract shows potent anti-fatigue effects; however, the active substance responsible for these effects remains undetermined. A glucomannan with a huge molecular size of 730 kDa, called DOP, was identified as the unique authentication marker of this expensive herb. DOP exhibited immunomodulating effects on macrophages and lymphocytes in our previous study. Clinical reports also showed that people with fatigue syndrome have a disturbed immune system. Because DOP is the unique and dominant component of D...
January 18, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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