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mechanical low back pain

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https://www.readbyqxmd.com/read/28822824/using-spinopelvic-parameters-to-estimate-residual-lumbar-lordosis-assuming-previous-lumbosacral-fusion-a-study-of-normative-values
#1
Hwee Weng Dennis Hey, Kimberly-Anne Tan, Shashidhar Bangalore Kantharajanna, Alex Quok An Teo, Chloe Xiaoyun Chan, Ka-Po Gabriel Liu, Hee-Kit Wong
BACKGROUND CONTEXT: Pelvic Incidence (PI) = Pelvic Tilt (PT) + Sacral Slope (SS) is an established trigonometric equation which can be expanded from studying the fixed pelvis with the spine to a fixed spinopelvic complex with the remnant spine, in scenarios of spinopelvic fusion or ankylosis. For a fixed spinopelvic complex, we propose the equation termed: Lumbar Incidence (LI) = Lumbar Tilt (LT) + Lumbar Slope (LS). PURPOSE: To establish reference values for LI, LT and LS at each lumbar vertebral level, and to show how LI can be used to determine rLL...
August 16, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28816770/prevalence-of-disability-in-patients-with-musculoskeletal-pain-and-rheumatic-diseases-in-a-population-from-cuenca-ecuador
#2
Sergio Vicente Guevara-Pacheco, Astrid Feican-Alvarado, Jorge Delgado-Pauta, Angelita Lliguisaca-Segarra, Ingris Pelaez-Ballestas
OBJECTIVE: The aim of this study was to determine the prevalence of disability in patients with musculoskeletal pain and rheumatic diseases in Cuenca, Ecuador. METHODS: We performed a cross-sectional analytical study with randomized sampling in 4877 subjects, from urban and rural areas. COPCORD (Community Oriented Program for Control of Rheumatic Diseases)-validated questionnaire was administered house-to-house to identify subjects with nontraumatic musculoskeletal pain and rheumatic diseases...
August 14, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28810990/gait-and-functional-outcomes-for-young-active-males-with-traumatic-unilateral-transfemoral-limb-loss
#3
Caitlin E Mahon, Alison L Pruziner, Brad D Hendershot, Erik J Wolf, Benjamin J Darter, K Bo Foreman, Joseph B Webster
OBJECTIVE: Altered body structures that occur with the loss of a lower limb can impact mobility and quality of life. Specifically, biomechanical changes that result from wearing a prosthesis have been associated with an increased risk of falls or joint degeneration, as well as increased energy demands. While previous studies describing these outcomes are typically limited by number of outcome measures and/or small, diverse patient groups, recent military conflicts present a unique opportunity to collect outcomes from a relatively homogenous, active patient population with limb loss...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28798688/establishment-and-characterization-of-a-novel-rat-model-of-mechanical-low-back-pain-using-behavioral-pharmacologic-and-histologic-methods
#4
Arjun Muralidharan, Thomas S W Park, John T Mackie, Luiz G S Gimenez, Andy Kuo, Janet R Nicholson, Laura Corradini, Maree T Smith
Chronic low back pain (LBP), the leading cause of disability globally, is notoriously difficult to treat. Most rodent models of LBP mimic lumbar radicular pain rather than mechanical LBP. Here, we describe establishment of a new rat model of mechanical LBP that is devoid of a neuropathic component. Groups of adult male Sprague Dawley rats were anesthetized and their lumbar L4/L5 and L5/L6 intervertebral disks (IVDs) were punctured (0.5 mm outer diameter, 2mm-deep) 5 (LPB-5X), or 10 (LBP-10X) times per disk...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28767620/effects-of-training-and-overtraining-on-intervertebral-disc-proteoglycans
#5
Renato H S Ueta, Victor A F Tarini, Carlos E Franciozi, Marcel J S Tamaoki, Valquíria P Medeiros, Helena B Nader, Flávio Faloppa
STUDY DESIGN: Animal experimental study OBJECTIVE.: Evaluate the effect of physical activity and overtraining condition on glycosaminoglycan concentration on the intervertebral disc (IVD) using a rat running model. SUMMARY OF BACKGROUND DATA: Some guidelines recommend the implementation of a physical exercise program as treatment for low back pain, however cyclic loading impact on the health of the intervertebral disc and whether there is a dose-response relationship is still incompletely understood...
August 1, 2017: Spine
https://www.readbyqxmd.com/read/28761372/application-of-advanced-biomechanical-methods-in-studying-low-back-pain-recent-development-in-estimation-of-lower-back-loads-and-large-array-surface-electromyography-and-findings
#6
REVIEW
Babak Bazrgari, Ting Xia
Low back pain (LBP) is a major public health problem and the leading disabling musculoskeletal disorder globally. A number of biomechanical methods using kinematic, kinetic and/or neuromuscular approaches have been used to study LBP. In this narrative review, we report recent developments in two biomechanical methods: estimation of lower back loads and large-array surface electromyography (LA-SEMG) and the findings associated with LBP. The ability to estimate lower back loads is very important for the prevention and the management of work-related low back injuries based on the mechanical loading model as one category of LBP classification...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28757287/sagittal-lumbo-pelvic-alignment-in-patients-with-low-back-pain-and-the-effects-of-a-high-load-lifting-exercise-and-individualized-low-load-motor-control-exercises-a-randomized-controlled-trial
#7
Lars Berglund, Björn Aasa, Peter Michaelson, Ulrika Aasa
Background Context Assessment of posture and lumbo-pelvic alignment is often a main focus in the classification and treatment of patients with low back pain. However, little is known regarding the effects of motor control interventions on objective measures of lumbo-pelvic alignment. Purpose The primary aim of this study was to describe the variation of sagittal lumbo-pelvic alignment in patients with nociceptive mechanical low back pain. The secondary aim was to compare the effects of a high-load lifting exercise (HLL) and low-load motor control exercises (LMC) on change in lumbo-pelvic alignment with a special emphasis on patients with high and low degrees of lumbar lordosis (lu) and sacral angle (sa)...
July 28, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28745679/-low-back-pain-and-modic-changes
#8
E L Sokov, L E Kornilova, A I Nesterov
Modic changes (MCh) are pathological changes in the bone marrow and the endplates of adjacent vertebrae characterized by bone marrow edema, fatty degeneration or osteosclerosis that are revealed by high-power field magnetic resonance imaging (MRI). The dominant disease pattern is a persistent back pain syndrome with varying intensity. It leads to difficulties in the interpretation of clinical data, evaluation of MRI data and treatment. The article presents a modern conception of the pathogenesis, classification, clinical implications and treatment of MCh based on national and foreign sources as well and the author's view on the osteogenic mechanism of the pathogenesis and treatment of MCh using intraosseous blockades...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28744842/the-quantitative-structural-and-compositional-analyses-of-degenerating-intervertebral-discs-using-magnetic-resonance-imaging-and-contrast-enhanced-micro-computed-tomography
#9
Kevin H Lin, Simon Y Tang
The intervertebral disc (IVD) is susceptible to degenerative changes that are associated with low back pain. Murine models are often used to investigate the mechanistic changes in the development, aging, and diseased states of the IVD, yet the detection of early degenerative changes in structure is challenging because of the minute size of the murine IVDs. Histology is the gold standard for examining the IVD structure, but it is susceptible to sectioning artifacts, spatial biases, and requires the destructive preparation of the sample...
July 25, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28742099/variants-of-acan-are-associated-with-severity-of-lumbar-disc-herniation-in-patients-with-chronic-low-back-pain
#10
Romain Shanil Perera, Poruwalage Harsha Dissanayake, Upul Senarath, Lalith Sirimevan Wijayaratne, Aranjan Lional Karunanayake, Vajira Harshadeva Weerabaddana Dissanayake
INTRODUCTION: Disc herniation is a complex spinal disorder associated with disability and high healthcare cost. Lumbar disc herniation is strongly associated with disc degeneration. Candidate genes of the aggrecan metabolic pathway may associate with the severity of lumbar disc herniation. OBJECTIVES: This study evaluated the association of single nucleotide variants (SNVs) of the candidate genes of the aggrecan metabolic pathway with the severity of lumbar disc herniation in patients with chronic mechanical low back pain...
2017: PloS One
https://www.readbyqxmd.com/read/28735027/translation-of-an-injectable-triple-interpenetrating-network-hydrogel-for-intervertebral-disc-regeneration-in-a-goat-model
#11
Sarah E Gullbrand, Thomas P Schaer, Prateek Agarwal, Justin R Bendigo, George R Dodge, Weiliam Chen, Dawn M Elliott, Robert L Mauck, Neil R Malhotra, Lachlan J Smith
Degeneration of the intervertebral discs is a progressive cascade of cellular, compositional and structural changes that is frequently associated with low back pain. As the first signs of disc degeneration typically arise in the disc's central nucleus pulposus (NP), augmentation of the NP via hydrogel injection represents a promising strategy to treat early to mid-stage degeneration. The purpose of this study was to establish the translational feasibility of a triple interpenetrating network hydrogel composed of dextran, chitosan, and teleostean (DCT) for augmentation of the degenerative NP in a preclinical goat model...
July 19, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28733722/non-specific-chronic-low-back-pain-differences-in-spinal-kinematics-in-subgroups-during-functional-tasks
#12
Rebecca Hemming, Liba Sheeran, Robert van Deursen, Valerie Sparkes
PURPOSE: A multidimensional classification approach suggests that motor control impairment subgroups exist in non-specific chronic low back pain (NSCLBP). Differences in sitting lumbar posture have been identified between two such subgroups [flexion pattern (FP) and active extension pattern (AEP)] and healthy individuals; however, functional spinal movement has not been explored. This study will evaluate whether NSCLBP subgroups exhibit regional spinal kinematic differences, compared to healthy individuals, during functional tasks...
July 21, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28727705/activation-of-the-rage-stat3-pathway-in-the-dorsal-root-ganglion-contributes-to-the-persistent-pain-hypersensitivity-induced-by-lumbar-disc-herniation
#13
Xin-Sheng Zhang, Xiao Li, Hai-Jie Luo, Zhu-Xi Huang, Cui-Cui Liu, Qing Wan, Shu-Wei Xu, Shao-Ling Wu, Song-Jian Ke, Chao Ma
BACKGROUND: Clinically, chronic low back pain and sciatica associated with lumbar disc herniation (LDH) is a common musculoskeletal disorder. Due to the unawareness of detailed mechanisms, it is difficult to get an effective therapy. OBJECTIVE: The aim of the present study was to identify the role of the RAGE/STAT3 pathway in the dorsal root ganglion (DRG) on the formation and development of persistent pain hypersensitivity induced by LDH. STUDY DESIGN: Controlled animal study...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28719509/the-relationship-between-structural-and-functional-brain-changes-and-altered-emotion-and-cognition-in-chronic-low-back-pain-a-systematic-review-of-mri-and-fmri-studies
#14
Sin Ki Ng, Donna M Urquhart, Paul B Fitzgerald, Flavia M Cicuttini, Sultana Monira Hussain, Bernadette M Fitzgibbon
OBJECTIVES: Chronic low back pain (CLBP) is a major health issue, yet its underlying mechanisms remain unknown. Studies have demonstrated the importance of emotion and cognition in chronic pain, however, the relevant brain physiology in magnetic resonance imaging (MRI) studies are unclear in CLBP populations. Therefore, this review aimed to identify MRI brain changes and examine their potential relationship with emotional and cognitive processes in CLBP. METHOD: A systematic search was conducted in 5 databases...
July 17, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28719458/acupuncture-for-chronic-pain-an-update-and-critical-overview
#15
Changshik Yin, Thomas E Buchheit, Jongbae J Park
PURPOSE OF REVIEW: Acupuncture is now recommended for several chronic pain conditions. Despite supportive evidence of its effectiveness, this ancient approach is often misunderstood, and may still be underused in mainstream practice. A critical review on its effectiveness and practice integration, and mechanisms of action is essential to the medical community that is continuing to seek nonopioid therapies for chronic pain. RECENT FINDINGS: Mounting evidence supports the effectiveness of acupuncture to treat chronic low back, neck, shoulder, and knee pain, as well as headaches...
July 15, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28719048/developmental-mechanisms-of-intervertebral-disc-and-vertebral-column-formation
#16
REVIEW
Lisa Y Lawson, Brian D Harfe
The vertebral column consists of repeating units of ossified vertebrae that are adjoined by fibrocartilagenous intervertebral discs. These structures form from the embryonic notochord and somitic mesoderm. In humans, congenital malformations of the vertebral column include scoliosis, kyphosis, spina bifida, and Klippel Feil syndrome. In adulthood, a common malady affecting the vertebral column includes disc degeneration and associated back pain. Indeed, recent reports estimate that low back pain is the number one cause of disability worldwide...
July 18, 2017: Wiley Interdisciplinary Reviews. Developmental Biology
https://www.readbyqxmd.com/read/28715273/physiological-effects-of-physical-therapy-interventions-on-lumbar-intervertebral-discs-a-systematic-review
#17
Ulrike H Mitchell, Kevin Helgeson, Paul Mintken
BACKGROUND CONTEXT: The use of physical therapy has been recommended in the treatment of low back pain based on primarily mechanical and neurophysiological effects. Recent studies have measured the physiological effects of physical therapy interventions, including manual therapy and traction, on the intervertebral discs (IVD), and these findings may have implications for the long-term management or even prevention of low back pain. PURPOSE: The objective of this systematic review is to investigate the literature regarding possible physiological effects of physical therapy interventions on the intervertebral disc (IVD)...
July 17, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28712541/mechanical-demands-on-the-lower-back-in-patients-with-non-chronic-low-back-pain-during-a-symmetric-lowering-and-lifting-task
#18
Iman Shojaei, Elizabeth G Salt, Quenten Hooker, Babak Bazrgari
There is limited information in the literature related to the lower back loading in patients with LBP, particularly those with non-chronic LBP. Toward addressing such a research gap, a case-control study was conducted to explore the differences in lower back mechanical loads between a group of females (n=19) with non-chronic, non-specific LBP and a group of asymptomatic females (n=19). The differences in lower back mechanical loads were determined when participants completed one symmetric lowering and lifting of a 4...
July 5, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28707222/considering-the-inferior-surface-area-of-lower-lumbar-vertebrae-determining-weight-transmission-pattern-at-the-lumbosacral-junction
#19
Uchenna Kenneth Ezemagu, Chike P Anibeze, Chinedu F Akpuaka
The biomechanical function of the lumbosacral junction (LSJ) is obscure, but its medical significance is not, as it is the most common site of low back pain. In this study, we analyzed the difference between the mean values of the surface areas of the inferior body and total inferior facet areas of the fourth and fifth lumbar vertebrae. We aimed to define the function of the LSJ during weight transmission and clarify its mechanical significance. Vertebral columns of 45 adult male human cadavers from five anatomy departments in Nigeria were cut at the L3-L4 intervertebral disc and macerated...
July 13, 2017: Anatomical Science International
https://www.readbyqxmd.com/read/28701365/mckenzie-method-of-mechanical-diagnosis-and-therapy-was-slightly-more-effective-than-placebo-for-pain-but-not-for-disability-in-patients-with-chronic-non-specific-low-back-pain-a-randomised-placebo-controlled-trial-with-short-and-longer-term-follow-up
#20
Alessandra Narciso Garcia, Lucíola da Cunha Menezes Costa, Mark J Hancock, Fabrício Soares de Souza, Geórgia Vieira Freschi de Oliveira Gomes, Matheus Oliveira de Almeida, Leonardo Oliveira Pena Costa
BACKGROUND: The McKenzie Method of Mechanical Diagnosis and Therapy (MDT) is one of the exercise approaches recommended by low back pain (LBP) guidelines. We investigated the efficacy of MDT compared with placebo in patients with chronic LBP. METHODS: This was a prospectively registered, two-arm randomised placebo controlled trial, with a blinded assessor. A total of 148 patients seeking care for chronic LBP were randomly allocated to either MDT (n=74) or placebo (n=74)...
July 12, 2017: British Journal of Sports Medicine
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