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mechanical low back pain

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https://www.readbyqxmd.com/read/29682329/active-discopathy-a-clinical-reality
#1
REVIEW
Margaux Boisson, Marie-Martine Lefèvre-Colau, François Rannou, Christelle Nguyen
In the late 1980s, the description by Modic and colleagues of elementary discovertebral changes detected on MRI (Modic classification) suggested for the first time a possible correlation between anatomical and clinical features in a subgroup of patients with non-specific chronic low back pain. Degenerative disc disease is frequent and usually asymptomatic, but Modic 1 changes in the vertebral endplates adjacent to a degenerated disc are associated with inflammatory-like chronic low back pain and low-grade local and systemic inflammation, which led to the concept of 'active discopathy'...
2018: RMD Open
https://www.readbyqxmd.com/read/29681973/effectiveness-of-massage-therapy-and-abdominal-hypopressive-gymnastics-in-nonspecific-chronic-low-back-pain-a-randomized-controlled-pilot-study
#2
L Bellido-Fernández, J J Jiménez-Rejano, R Chillón-Martínez, M A Gómez-Benítez, M De-La-Casa-Almeida, M Rebollo-Salas
Background: There are a great number of interventions in physiotherapy, but with little evidence of their effectiveness in chronic low back pain. Therefore, this study assesses effectiveness of Massage Therapy and Abdominal Hypopressive Gymnastics and the combination of both to decrease pain and lumbar disability while increasing joint mobility and quality of life in patients with chronic nonspecific low back pain. Methods: A randomized, single-blinded, controlled, clinical trial with sample ( n = 27) was comprised of patients between 20 and 65 years, diagnosed with pain of mechanical origin characterized by having a duration of at least 12 weeks and no serious complications...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29669311/a-new-clinical-model-for-facilitating-the-development-of-pattern-recognition-skills-in-clinical-pain-assessment
#3
David M Walton, James M Elliott
Common, enigmatic musculoskeletal conditions such as whiplash-associated disorder, myofascial pain syndrome, low back pain, headache, fibromyalgia, osteoarthritis, and rotator cuff pathology, account for significant social, economic, and personal burdens on a global scale. Despite their primacy (and shared sequelae) there remains a paucity of available and effective management options for patients with both acute and chronic conditions. Establishing an accurate prognostic or diagnostic profile on a patient-by-patient basis can challenge the insight of both novice and expert clinicians...
April 9, 2018: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/29669088/paradigm-shift-in-geriatric-low-back-pain-management-integrating-influences-experiences-and-consequences
#4
Corey B Simon, Gregory E Hicks
Geriatric low back pain (LBP) can have a profound impact on physical activity and can cause a decline in physical function, which is a major health risk for older adults. Within the last decade, physical therapist management of LBP has shifted from an emphasis on pathoanatomical mechanisms, such as spine degeneration, to addressing psychological distress factors. Although this approach is promising, the complexity of LBP in older adults (including biological, psychological, cognitive, and social influences), which may differ from that in younger adults, must be considered...
May 1, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29644469/-cognitive-bias-research-and-depression-in-chronic-pain
#5
REVIEW
A C Rusu, J Hülsebusch
Chronic back pain is of enormous health and economic relevance for industrialized countries because a small group of patients with chronic disease is responsible for a large proportion of medical costs. The prevention of chronic disease is therefore a primary goal in the treatment of patients with acute low back pain. Psychological factors are the central risk factors for later chronification. Above all, especially depressive symptoms and occupational distress, as well as various maladaptive forms of pain management are central risk factors...
April 11, 2018: Der Schmerz
https://www.readbyqxmd.com/read/29628809/cytokine-involvement-in-biological-inflammation-related-to-degenerative-disorders-of-the-intervertebral-disk-a-narrative-review
#6
REVIEW
Christopher M De Geer
Objective: The purpose of this narrative literature review is to discuss the literature regarding the potential role that cytokines play in degenerative disk disease. Methods: The inclusion criteria were studies that used inflammatory mediators in advancing disk disease processes. Research studies were limited to the last 3 decades that had free full-text available online in English. Exclusion criteria were review articles and articles pertaining to temporomandibular joints and other joints of the body other than the intervertebral disk...
March 2018: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/29623654/tapentadol-extended-release-in-the-treatment-of-severe-chronic-low-back-pain-and-osteoarthritis-pain
#7
REVIEW
Joseph V Pergolizzi, Robert Taylor, Jo Ann LeQuang, Robert B Raffa, John Bisney
Tapentadol is a novel pain reliever with apparently synergistic dual mechanisms of action, capable of addressing both nociceptive and neuropathic components of chronic pain. As an effective analgesic with good tolerability, tapentadol may be appropriate for patients suffering from severe chronic pain associated with low back pain (LBP) or osteoarthritis (OA). Efficacy studies of tapentadol in populations of patients with severe chronic LBP or OA pain suggest that tapentadol is non-inferior to oxycodone. Its tolerability, especially with respect to gastrointestinal (GI) side effects, may be better than that of other strong opioids in clinical trials and analyses of multiple trials...
April 5, 2018: Pain and Therapy
https://www.readbyqxmd.com/read/29620648/epiduroscopic-laser-neural-decompression-as-a-treatment-for-migrated-lumbar-disc-herniation-case-series
#8
Jinyoung Oh, Daehyun Jo
OBJECTIVE: Epiduroscopic laser neural decompression (ELND) is one of the more invasive techniques for managing patients with herniated lumbar disc. However, ELND can be used to treat, and diagnose the epidural pathology; indications for ELND remain controversial, especially, when applied in cases of large disc extrusion and migrated disc. This paper reports cases of patients that were satisfied with the ELND procedure for migrated lumbar disc herniation. METHODS: We reviewed the medical records of patients that received ELND for migrated lumbar disc in an outpatient clinic...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29616222/does-a-better-perfusion-of-deconditioned-muscle-tissue-release-chronic-low-back-pain
#9
Paola Valdivieso, Martino V Franchi, Christian Gerber, Martin Flück
Non-specific chronic low back pain (nsCLBP) is a multifactorial condition of unknown etiology and pathogenesis. Physical and genetic factors may influence the predisposition of individuals to CLBP, which in many instances share a musculoskeletal origin. A reduced pain level in low back pain patients that participate in exercise therapy highlights that disuse-related muscle deconditioning may predispose individuals to nsCLBP. In this context, musculoskeletal pain may be the consequence of capillary rarefaction in inactive muscle as this would lower local tissue drainage and washing out of toxic waste...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29614622/determination-of-physical-parameters-associated-with-self-efficacy-in-patients-with-chronic-mechanic-low-back-pain
#10
M Duray, N Yagci, N Ok
BACKGROUND: Self-efficacy that is associated with various pain-related disabilities such as chronic low back pain (LBP), should be questioned besides physical assessments. OBJECTIVES: To investigate the physical factors associated with self-efficacy in patients with chronic mechanic LBP. METHODS: One hundred nine patients diagnosed as chronic mechanic LBP (65 females, 44 males) between 20-50 years old were included to this study. The intensity of LBP was assessed by using a 10-cm Visual Analogue Scale...
March 23, 2018: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29605718/a-novel-mouse-model-of-intervertebral-disc-degeneration-shows-altered-cell-fate-and-matrix-homeostasis
#11
Hyowon Choi, Steven Tessier, Elizabeth S Silagi, Rutvin Kyada, Farzad Yousefi, Nancy Pleshko, Irving M Shapiro, Makarand V Risbud
Intervertebral disc degeneration and associated low back and neck pain is a ubiquitous health condition that affects millions of people world-wide, and causes high incidence of disability and enormous medical/societal costs. However, lack of appropriate small animal models with spontaneous disease onset has impeded our ability to understand the pathogenetic mechanisms that characterize and drive the degenerative process. We report, for the first time, early onset spontaneous disc degeneration in SM/J mice known for their poor regenerative capacities compared to "super-healer" LG/J mice...
March 29, 2018: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/29602304/effectiveness-of-the-mckenzie-method-mechanical-diagnosis-and-therapy-for-treating-low-back-pain-literature-review-with-meta-analysis
#12
Olivier T Lam, David M Strenger, Matthew Chan-Fee, Paul Thuong Pham, Richard A Preuss, Shawn M Robbins
Study Design Literature review with meta-analysis. Background Mechanical Diagnosis and Therapy (MDT), a classification-based system, aims to classify patients into homogenous subgroups to direct treatment. Objectives To examine MDT's effectiveness for improving pain and disability in patients with either acute (<12 weeks duration) or chronic (>12 weeks duration) low back pain (LBP). Methods Randomized controlled trials examining MDT in patients with LBP were identified from 6 databases. Independent investigators assessed the studies for exclusion, extracted data, and assessed risk of bias...
March 30, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29592979/spondylodiscitis-in-a-54-year-old-female-scuba-diver
#13
Neil Tuttle, Alexandra Brelis, Rachel Brereton, Kerrie Evans
A 54-year-old woman presented to a Sports Physician with a 4-year history of haemochromatosis, and she had a medical history that included a congenital spondylolisthesis resulting in a fusion of L4-S1 at age 16 years, episodic mechanical low back pain and an absence of other significant musculoskeletal symptoms. On presentation, she reported 18 months of severe low back pain that started after a scuba diving trip. After the onset of this low back pain, she developed gastrointestinal symptoms from Salmonella The gastrointestinal symptoms improved with a course of antibiotics, but the back pain persisted in spite of analgesics, non-steroidal anti-inflammatories and several attempts at different conservative management...
March 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29588584/a-novel-electrospun-aligned-nanoyarn-three-dimensional-porous-nanofibrous-hybrid-scaffold-for-annulus-fibrosus-tissue-engineering
#14
Jun Ma, Yunfei He, Xilin Liu, Weiming Chen, An Wang, Chia-Ying Lin, Xiumei Mo, Xiaojian Ye
Introduction: Herniation of the nucleus pulposus (NP) because of defects in the annulus fibrosus (AF) is a well-known cause of low back pain. Defects in the AF thus remain a surgical challenge, and efforts have been made to develop new techniques for closure and repair. In this study, we developed an electrospun aligned nanoyarn scaffold (AYS) and nanoyarn/three-dimensional porous nanofibrous hybrid scaffold (HS) for AF tissue engineering. Methods: The AYS was fabricated via conjugated electrospinning, while the aligned nanofibrous scaffold (AFS) was prepared by traditional electrospinning as a baseline scaffold...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29573870/what-low-back-pain-is-and-why-we-need-to-pay-attention
#15
REVIEW
Jan Hartvigsen, Mark J Hancock, Alice Kongsted, Quinette Louw, Manuela L Ferreira, Stéphane Genevay, Damian Hoy, Jaro Karppinen, Glenn Pransky, Joachim Sieper, Rob J Smeets, Martin Underwood
Low back pain is a very common symptom. It occurs in high-income, middle-income, and low-income countries and all age groups from children to the elderly population. Globally, years lived with disability caused by low back pain increased by 54% between 1990 and 2015, mainly because of population increase and ageing, with the biggest increase seen in low-income and middle-income countries. Low back pain is now the leading cause of disability worldwide. For nearly all people with low back pain, it is not possible to identify a specific nociceptive cause...
March 20, 2018: Lancet
https://www.readbyqxmd.com/read/29571115/compressive-fatigue-properties-of-commercially-available-standard-and-low-modulus-acrylic-bone-cements-intended-for-vertebroplasty
#16
Céline Robo, Caroline Öhman-Mägi, Cecilia Persson
Vertebroplasty (VP) is a minimally invasive surgical procedure commonly used to relieve severe back pain associated with vertebral compression fractures. The poly(methyl methacrylate) bone cement used during this procedure is however presumed to facilitate the occurrence of additional fractures next to the treated vertebrae. A reason for this is believed to be the difference in stiffness between the bone cement and the surrounding trabecular bone. The use of bone cements with lower mechanical properties could therefore reduce the risk of complications post-surgery...
March 8, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29565945/is-vitamin-d-supplementation-effective-for-low-back-pain-a-systematic-review-and-meta-analysis
#17
Joshua R Zadro, Debra Shirley, Manuela Ferreira, Ana Paula Carvalho Silva, Sarah E Lamb, Cyrus Cooper, Paulo H Ferreira
BACKGROUND: Low back pain (LBP) is the leading cause of years lived with disability worldwide. Current intervention strategies are failing to reduce the enormous global burden of LBP and are prompting researchers to investigate alternative management strategies, such as vitamin D supplementation. Vitamin D supplementation appears to down regulate pro-inflammatory cytokines which lead to pain and up regulate anti-inflammatory cytokines that reduce inflammation. These mechanisms might explain the increasing interest in the use of vitamin D supplementation for LBP...
March 2018: Pain Physician
https://www.readbyqxmd.com/read/29562974/you-re-the-flight-surgeon
#18
(no author information available yet)
Haight SP, Sholes PC, Pokorny WB, Brandenburg LR. You're the flight surgeon: other causes of mechanical low back pain. Aerosp Med Hum Perform. 2018; 89(4):411-413.
April 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29554650/dysregulated-mir-3150a-3p-promotes-lumbar-intervertebral-disc-degeneration-by-targeting-aggrecan
#19
Bin Zhang, Wei Guo, Chao Sun, Hui-Quan Duan, Bing-Bing Yu, Kun Mu, Yue-Yan Guan, Yan Li, Shen Liu, Yang Liu, De-Xiang Ban, Wen-Dong Ruan, Xiao-Hong Kong, Cong Xing, Guang-Zhi Ning, Shi-Qing Feng
BACKGROUND/AIMS: Low back pain has become one of the most common musculoskeletal diseases in the world. Studies have shown that intervertebral disc degeneration (IDD) is an important factor leading to low back pain, but the mechanisms underlying IDD remain largely unknown. Research over the past decade has suggested critical roles for microRNAs (miRNAs) in natural growth and disease progression. However, it remains poorly understood whether circular RNAs participate in IDD. METHODS: Clinical IDD samples were collected from 20 patients who underwent discectomy...
March 15, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29526797/melatonin-resists-oxidative-stress-induced-apoptosis-in-nucleus-pulposus-cells
#20
Ruijun He, Min Cui, Hui Lin, Lei Zhao, Jiayu Wang, Songfeng Chen, Zengwu Shao
AIMS: Intervertebral disc degeneration (IVDD) is thought to be the major cause of low back pain (LBP), which is still in lack of effective etiological treatment. Oxidative stress has been demonstrated to participate in the impairment of nucleus pulposus cells (NPCs). As the most important neuroendocrine hormone in biological clock regulation, melatonin (MLT) is also featured by good antioxidant effect. In this study, we investigated the effect and mechanisms of melatonin on oxidative stress-induced damage in rat NPCs...
March 8, 2018: Life Sciences
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