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mechanical low back pain

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https://www.readbyqxmd.com/read/29042813/rehabilitation-management-of-low-back-pain-it-s-time-to-pull-it-all-together
#1
Yannick Tousignant-Laflamme, Marc Olivier Martel, Anand B Joshi, Chad E Cook
In the past, rehabilitation research initiatives for low back pain (LBP) have targeted outcome enhancement through personalized treatment approaches, namely through classification systems (CS). Although the use of CS has enhanced outcomes, common management practices have not changed, the prevalence of LBP is still high, and only selected patients meet the CS profile, namely those with a nociceptive context. Similarly, although practice guidelines propose some level of organization and occasionally a timeline of care provision, each mainly provides best practice for isolated treatment approaches...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/29033606/the-pain-depression-disability-pathway-in-those-with-low-back-pain-a-moderation-analysis-of-health-locus-of-control
#2
Paul Campbell, Kate Hope, Kate M Dunn
Low back pain (LBP) is common, impacts on the individual and society, and is a major health concern. Psychological consequences of LBP, such as depression, are significant barriers to recovery, but mechanisms for the development of depression are less well understood. One potential mechanism is the individual's health locus of control (HLoC), that is, perception of the level of control an individual has over their health. The objective of this study is to investigate the moderation effect of HLoC on the pain-depression-disability pathway in those with LBP...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/29030287/inhibition-of-pain-and-pain-related-brain-activity-by-heterotopic-noxious-counter-stimulation-and-selective-attention-in-chronic-non-specific-low-back-pain
#3
Alexandra Ladouceur, Nabi Rustamov, Jean-Daniel Dubois, Jessica Tessier, Alexandre Lehmann, Martin Descarreaux, Pierre Rainville, Mathieu Piché
The aim of the present study was to assess inhibition of pain and somatosensory-evoked potentials (SEPs) by heterotopic noxious counter-stimulation (HNCS) and by selective attention in patients with chronic non-specific LBP. Seventeen patients and age/sex-matched controls were recruited (10 men, 7 women; mean age ± SD: 43.3 ± 10.4 and 42.7 ± 11.1, respectively). On average, patients with LBP reported pain duration of 7.6 ± 6.5 years, light to moderate disability (19.3 ± 5.7/100) and low clinical pain intensity (21...
October 10, 2017: Neuroscience
https://www.readbyqxmd.com/read/29026131/mechanical-stress-induces-elastic-fibre-disruption-and-cartilage-matrix-increase-in-ligamentum-flavum
#4
Kazunori Hayashi, Akinobu Suzuki, Sayed Abdullah Ahmadi, Hidetomi Terai, Kentaro Yamada, Masatoshi Hoshino, Hiromitsu Toyoda, Shinji Takahashi, Koji Tamai, Shoichiro Ohyama, Akgar Javid, Mohammad Suhrab Rahmani, Maruf Mohammad Hasib, Hiroaki Nakamura
Lumbar spinal stenosis (LSS) is one of the most frequent causes of low back pain and gait disturbance in the elderly. Ligamentum flavum (LF) hypertrophy is the main pathomechanism of LSS, but the reason for its occurrence is not clearly elucidated. In this study, we established a novel animal model of intervertebral mechanical stress concentration and investigated the biological property of the LF. The LF with mechanical stress concentration showed degeneration with elastic fibres disruption and cartilage matrix increase, which are similar to the findings in hypertrophied LF from patients with LSS...
October 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29019640/spine-conditions-mechanical-and-inflammatory-low-back-pain
#5
Christopher Ledford
Mechanical low back pain (LBP) is an injury or derangement of an anatomic structure in the low back. When evaluating patients with LBP, clinicians should maintain clinical suspicion for vertebral fracture, cancer, and cauda equina syndrome. Management includes patient education focused on exercise, massage, and behavioral approaches such as cognitive behavioral therapy. Acupuncture can be an effective alternative and specific herbal supplements may provide short-term pain relief. The prognosis for patients with mechanical LBP is good...
October 2017: FP Essentials
https://www.readbyqxmd.com/read/28993681/equiaxial-strain-modulates-adipose-derived-stem-cell-differentiation-within-3d-biphasic-scaffolds-towards-annulus-fibrosus
#6
Mostafa Elsaadany, Kayla Winters, Sarah Adams, Alexander Stasuk, Halim Ayan, Eda Yildirim-Ayan
Recurrence of intervertebral disc (IVD) herniation is the most important factor leading to chronic low back pain and subsequent disability after discectomy. Efficacious annulus fibrosus (AF) repair strategy that delivers cells and biologics to IVD injury site is needed to limit the progression of disc degeneration and promote disc self-regeneration capacities after discectomy procedures. In this study, a biphasic mechanically-conditioned scaffold encapsulated with human adipose-derived stem cells (ASCs) is studied as a potential treatment strategy for AF defects...
October 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28990805/experimental-evidence-for-weaker-endogenous-inhibition-of-trigeminal-pain-than-extra-trigeminal-pain-in-healthy-individuals
#7
Dan Levy, Lorin Abdian, Michal Dekel-Steinkeller, Ruth Defrin
Background and objectives The prevalence of pain syndromes that affect the territories innervated by the trigeminal nerve, such as headaches, is one of the highest and ranks second only to low back pain. A potential mechanism underlying this high prevalence may be a relatively weak endogenous pain modulation of trigeminal pain. Here, we sought to systematically compare endogenous pain modulation capabilities in the trigeminal region to those of extra-trigeminal regions in healthy subjects. Methods Healthy, pain free subjects (n = 17) underwent a battery of quantitative sensory testing to assess endogenous pain inhibition and pain enhancement efficiencies within and outside the trigeminal innervated region...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28989073/psychological-features-and-their-relationship-to-movement-based-subgroups-in-people-living-with-low-back-pain
#8
Nicholas V Karayannis, Gwendolen A Jull, Michael K Nicholas, Paul W Hodges
OBJECTIVE: To determine the distribution of higher psychological risk features within movement-based subgroups for people with Low Back Pain (LBP) DESIGN: Cross-sectional observational study SETTING: Participants were recruited from physiotherapy clinics and community advertisements. Measures were collected at a university outpatient-based physiotherapy clinic. PARTICIPANTS: 102 people seeking treatment for LBP INTERVENTIONS: Participants were subgrouped according to three classification schemes: Mechanical Diagnosis and Treatment (MDT), Treatment Based Classification (TBC) and O'Sullivan Classification (OSC)...
October 5, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28967362/pain-management-in-rheumatology-research-training-and-practice
#9
REVIEW
David G Borenstein, Afton L Hassett, David Pisetsky
The Pain Management Task Force of the American College of Rheumatology published a report in 2010 highlighting pain management as a fundamental aspect of clinical practice, training and research. In the interim, the consideration of pain as a focus of attention of rheumatologists and rheumatology health professionals has become even more challenging than in 2010 because of the epidemic of opiate addiction and overdose death. The characterisation of categories of pain by mechanism (e.g., inflammation, joint degeneration, abnormalities of central pain processing) can help guide treatment...
September 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28967357/in-the-spine-or-in-the-brain-recent-advances-in-pain-neuroscience-applied-in-the-intervention-for-low-back-pain
#10
REVIEW
Jo Nijs, Jacqui Clark, Anneleen Malfliet, Kelly Ickmans, Lennard Voogt, Sanneke Don, Hester den Bandt, Dorien Goubert, Jeroen Kregel, Iris Coppieters, Wim Dankaerts
Conservative, surgical and pharmacological strategies for chronic low back pain (CLBP) management offer at best modest effect sizes in reducing pain and related disability, indicating a need for improvement. Such improvement may be derived from applying contemporary pain neuroscience to the management of CLBP. Current interventions for people with CLBP are often based entirely on a "biomedical" or "psychological" model without consideration of information concerning underlying pain mechanisms and contemporary pain neuroscience...
September 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28962911/from-the-international-space-station-to-the-clinic-how-prolonged-unloading-may-disrupt-lumbar-spine-stability
#11
Jeannie F Bailey, Stephanie L Miller, Kristine Khieu, Conor W O'Neill, Robert M Healey, Dezba G Coughlin, Jojo V Sayson, Douglas G Chang, Alan R Hargens, Jeffrey C Lotz
Background context Prolonged microgravity exposure is associated with localized low back pain and an elevated risk of post-flight disc herniation. Though the mechanisms by which microgravity impairs the spine are unclear, they should be foundational for developing in-flight countermeasures for maintaining astronaut spine health. Because human spine anatomy has adapted to upright posture on Earth, observations of how spaceflight affects the spine should also provide new and potentially important information on spine biomechanics that benefit the general population...
September 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28952872/kinematics-of-the-spine-during-sit-to-stand-using-motion-analysis-systems-a-systematic-review-of-literature
#12
Mohammad Reza Pourahmadi, Ismail Ebrahimi Takamjani, Shapour Jaberzadeh, Javad Sarrafzadeh, Mohammad Ali Sanjari, Rasool Bagheri, Morteza Taghipour
BACKGROUND CONTEXT: Clinical evaluation of the spine is commonplace in musculoskeletal therapies such as physiotherapy, physical medicine/rehabilitation, osteopathic, and chiropractic clinics. Sit-to-stand (STS) is one of the most mechanically demanding of daily activities and crucial to independence. Difficulty or inability to perform STS is common in individuals with a variety of motor disabilities such as low back pain. OBJECTIVE: The purpose of this systematic review was to evaluate available evidence in literature to determine 2D and 3D kinematics of the spine during STS in patients with LBP and healthy young adult participants using motion analysis systems (electromagnetic and marker based)...
September 27, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28933804/concurrent-lumbosacral-and-sacrococcygeal-fusion-a-rare-etiology-of-low-back-pain-and-coccygodynia
#13
Stylianos Kapetanakis, Grigorios Gkasdaris, Pavlos Pavlidis, Panagiotis Givissis
BACKGROUND: Sacrum is a triangular bone placed in the base of the spine and formed by the synostosis of five sacral vertebrae (S1-S5). Its upper part is connected with the inferior surface of the body of L5 vertebra forming the lumbosacral joint, while its lower part is connected with the base of the coccyx forming the sacrococcygeal symphysis, an amphiarthrodial joint. The existence of four pairs of sacral foramen in both anterior and posterior surface of the sacrum is the most common anatomy...
September 21, 2017: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/28928587/unexpected-complication-after-caudal-epidural-steroid-injection-hiccup
#14
Ayhan Kaydu, Ebru Tarıkçı Kılıç, Erhan Gökçek, Mehmet Salim Akdemir
Persistent hiccup is uncommon, and the mechanism is poorly understood. We present the case of a 43-year-old male patient referred to the Algology department due to chronic back pain who developed what we believe a rare case of persistent hiccup secondary to caudal epidural steroid injection (CESI). The causes of hiccup are many and include electrolyte derangement, nutritional deficiencies, gastrointestinal disorders and instrumentation, cardiovascular disorders, renal impairment, central nervous system disorders, and drugs; however, the cause may be unknown...
July 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28921656/animal-models-for-studying-the-etiology-and-treatment-of-low-back-pain
#15
REVIEW
Changgui Shi, Sujun Qiu, Scott M Riester, Vaskar Das, Bingqian Zhu, Atiyayein A Wallace, Andre J van Wijnen, Fackson Mwale, James C Iatridis, Daisuke Sakai, Gina Votta-Velis, Wen Yuan, Hee-Jeong Im
Chronic low back pain is a major cause of disability and health care costs. Effective treatments are inadequate for many patients. Animal models are essential to further understanding of the pain mechanism and testing potential therapies. Currently, a number of preclinical models have been developed attempting to mimic aspects of clinical conditions that contribute to low back pain. This review focused on describing these animal models and the main behavioral tests for assessing pain in each model. Animal models of low back pain can be divided into the following five categories: discogenic low back pain, radicular back pain, facet joint osteoarthritis back pain, muscle-induced low back pain, and spontaneous occurring low back pain models...
September 18, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28920043/short-term-analgesic-effects-of-5-dextrose-epidural-injections-for-chronic-low-back-pain-a-randomized-controlled-trial
#16
Liza Maniquis-Smigel, Kenneth Dean Reeves, Howard Jeffrey Rosen, John Lyftogt, Cassie Graham-Coleman, An-Lin Cheng, David Rabago
BACKGROUND: Hypertonic dextrose injection (prolotherapy) is reported to reduce pain including non-surgical chronic low back pain (CLBP), and subcutaneous injection of 5% dextrose is reported to reduce neurogenic pain, hyperalgesia and allodynia. The mechanism in both cases is unclear, though a direct effect of dextrose on neurogenic pain has been proposed. This study assessed the short-term analgesic effects of epidural 5% dextrose injection compared with saline for non-surgical CLBP...
February 2017: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/28919806/how-stable-are-quantitative-sensory-testing-measurements-over-time-report-on-10-week-reliability-and-agreement-of-results-in-healthy-volunteers
#17
Helen Nothnagel, Christian Puta, Thomas Lehmann, Philipp Baumbach, Martha B Menard, Brunhild Gabriel, Holger H W Gabriel, Thomas Weiss, Frauke Musial
BACKGROUND: Quantitative sensory testing (QST) is a diagnostic tool for the assessment of the somatosensory system. To establish QST as an outcome measure for clinical trials, the question of how similar the measurements are over time is crucial. Therefore, long-term reliability and limits of agreement of the standardized QST protocol of the German Research Network on Neuropathic Pain were tested. METHODS: QST on the lower back and hand dorsum (dominant hand) were assessed twice in 22 healthy volunteers (10 males and 12 females; mean age: 46...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28900711/evidence-of-splinting-in-low-back-pain-a-systematic-review-of-perturbation-studies
#18
REVIEW
Maarten R Prins, Mariëtte Griffioen, Thom T J Veeger, Henri Kiers, Onno G Meijer, Peter van der Wurff, Sjoerd M Bruijn, Jaap H van Dieën
PURPOSE: The purpose of this systematic review was to assess whether LBP patients demonstrate signs of splinting by evaluating the reactions to unexpected mechanical perturbations in terms of (1) trunk muscle activity, (2) kinetic and (3) kinematic trunk responses and (4) estimated mechanical properties of the trunk. METHODS: The literature was systematically reviewed to identify studies that compared responses to mechanical trunk perturbations between LBP patients and healthy controls in terms of muscle activation, kinematics, kinetics, and/or mechanical properties...
September 12, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28874978/prevalence-patterns-and-genetic-association-analysis-of-modic-vertebral-endplate-changes
#19
Rishi Mugesh Kanna, Rajasekaran Shanmuganathan, Veera Ranjani Rajagopalan, Senthil Natesan, Raveendran Muthuraja, Kenneth Man Chee Cheung, Danny Chan, Patrick Yu Ping Kao, Anita Yee, Ajoy Prasad Shetty
STUDY DESIGN: A prospective genetic association study. PURPOSE: The etiology of Modic changes (MCs) is unclear. Recently, the role of genetic factors in the etiology of MCs has been evaluated. However, studies with a larger patient subset are lacking, and candidate genes involved in other disc degeneration phenotypes have not been evaluated. We studied the prevalence of MCs and genetic association of 41 candidate genes in a large Indian cohort. OVERVIEW OF LITERATURE: MCs are vertebral endplate signal changes predominantly observed in the lumbar spine...
August 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28863296/associations-of-prolonged-standing-with-musculoskeletal-symptoms-a-systematic-review-of-laboratory-studies
#20
REVIEW
Pieter Coenen, Sharon Parry, Lisa Willenberg, Joyce W Shi, Lorena Romero, Diana M Blackwood, Genevieve N Healy, David W Dunstan, Leon M Straker
While prolonged standing has shown to be detrimentally associated with musculoskeletal symptoms, exposure limits and underlying mechanisms are not well understood. We systematically reviewed evidence from laboratory studies on musculoskeletal symptom development during prolonged (≥20min) uninterrupted standing, quantified acute dose-response associations and described underlying mechanisms. Peer-reviewed articles were systematically searched for. Data from included articles were tabulated, and dose-response associations were statistically pooled...
October 2017: Gait & Posture
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