keyword
MENU ▼
Read by QxMD icon Read
search

mechanical low back pain

keyword
https://www.readbyqxmd.com/read/28430617/estrogen-receptors-involvement-in-intervertebral-discogenic-pain-of-the-elderly-women-colocalization-and-correlation-with-the-expression-of-substance-p-in-nucleus-pulposus
#1
Xiao-Xing Song, Sheng Shi, Zhen Guo, Xin-Feng Li, Bu-Wei Yu
Estrogenic modulation of pain is an exceedingly complex phenomenon. However, whether estrogen is involved in discogenic low back pain still remains unclear. Here, immunoreactivity staining technique was used to examine the expression level of the estrogen receptors (ERα and ERβ) and a pain related neuropeptide, Substance P in the lumbar intervertebral discs to analyze the relationship between the ERs and Substance P. Nucleus pulposus tissues of 23 elderly female patients were harvested during spinal surgeries and made to detect the immunoreactivity staining of ERα, ERβ and Substance P...
February 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423222/persistent-and-developing-sleep-problems-a-prospective-cohort-study-on-the-relationship-to-poor-outcome-in-patients-attending-a-pain-clinic-with-chronic-low-back-pain
#2
Amir H Pakpour, Mohammadhossein Yaghoubidoust, P Campbell
Sleep problems are common in people with low back pain (LBP), however the mechanisms on how sleep influences pain are complex. To date there is a lack of prospective research on the timings and the development of sleep problems in those who have LBP, such information would be useful to identify individuals at risk of poor outcome. Aims are to investigate the predictive role of sleep problems on self-report recovery and pain intensity using logistic regression reporting Odds Ratios (OR). An observational cohort of 761 chronic LBP patients recruited from a pain management clinic participated, and completed data at baseline, and at 6 month follow-up (n = 682)...
April 18, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28387658/do-turkish-patients-with-lumbar-disc-herniation-know-body-mechanics
#3
Sacide Yildizeli Topcu
BACKGROUND AND OBJECTIVE: Most common and important cause of the low back pain is lumbar disc herniation. Patients with lumbar disc herniation face with difficulties during daily activities due to the reduction of physical functions. In order to maintain daily activities without pain and discomfort, the patients should be informed about proper positions and body mechanics. The aim of the study was to determine the knowledge and the applications of the patients with lumbar disc herniation about body mechanics...
March 31, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28387615/ectopic-expression-of-smurf2-and-acceleration-of-age-related-intervertebral-disc-degeneration-in-a-mouse-model
#4
Qiuqian Wu, Jason H Huang
OBJECTIVE Lumbar intervertebral disc degeneration, an age-related process, is a major cause of low-back pain. Although low-back pain is a very common clinical problem in the aging population, no effective treatment is available, largely owing to lack of understanding of the molecular mechanisms underlying disc degeneration. The goal of this study was to characterize how ectopic expression of Smurf2 driven by the collagen Type II alpha 1 ( Col2a1) promoter alters disc cell phenotype and associated cellular events, matrix synthesis, and gene expression during disc degeneration in mice...
April 7, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28380300/biophysical-study-on-the-interaction-between-eperisone-hydrochloride-and-human-serum-albumin-using-spectroscopic-calorimetric-and-molecular-docking-analysis
#5
Gulam Rabbani, Mohammad Hassan Baig, Eun Ju Lee, Won Kyung Cho, Jin Yeul Ma, Inho Choi
Eperisone hydrochloride (EH) is a widely used as a muscle relaxant for patients with muscular contracture, low back pain, or spasticity. Human serum albumin (HSA), a highly soluble negatively charged, endogenous and abundant plasma protein ascribed with the ligand binding and transport properties. The current study was undertaken to explore the interaction between EH and the serum transport protein, HSA. Study of the interaction between HSA and EH was carried by UV-vis, fluorescence quenching, circular dichroism (CD) spectroscopy, FRET, and ITC...
April 5, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28376786/psychological-predictors-of-change-in-the-number-of-musculoskeletal-pain-sites-among-norwegian-employees-a-prospective-study
#6
Jan Olav Christensen, Sissel Johansen, Stein Knardahl
BACKGROUND: The pathogenesis of syndromes of widespread musculoskeletal pain remains an enigma. The present study sought to determine if psychological states, job satisfaction, pain intensity, and sleep problems contributed to the spread and decline of the number of musculoskeletal pains. METHODS: A sample of 2989 Norwegian employees completed a questionnaire at baseline and follow-up 2 years later. Data were analyzed with multinomial and ordinal logistic regression analyses to determine effects on direction and degree of change of number of pain sites (NPS)...
April 4, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28376368/brain-derived-neurotrophic-factor-plasma-levels-are-increased-in-older-women-after-an-acute-episode-of-low-back-pain
#7
Juliano Bergamaschine Mata Diz, Bruno de Souza Moreira, Diogo Carvalho Felício, Luiza Faria Teixeira, Fabianna Resende de Jesus-Moraleida, Bárbara Zille de Queiroz, Daniele Sirineu Pereira, Leani Souza Máximo Pereira
BACKGROUND: Low back pain (LBP) is a growing public health problem in old age, and it is associated with disabling pain and depressive disorders. We compared brain-derived neurotrophic factor (BDNF) plasma levels, a key neurotrophin in pain modulation, between older women after an acute episode of LBP and age-matched pain-free controls, and investigated potential differences in BDNF levels between controls and LBP subgroups based on pain severity, presence of depressive symptoms and use of analgesic and antidepressant drugs...
March 22, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28371810/characteristics-of-the-musculoskeletal-symptoms-observed-among-survivors-of-ebola-virus-disease-in-the-postebogui-cohort-in-guinea
#8
Yves-Marie Pers, Mamadou Saliou Sow, Bernard Taverne, Laura March, Suzanne Izard, Jean François Étard, Moumié Barry, Abdoulaye Touré, Eric Delaporte
Objective.: Previous studies show that arthralgia is the most common symptom experienced by Ebola virus disease (EVD) survivors. Nevertheless, specific analyses of rheumatological sequelea are still lacking. Methods.: The Postebogui study is a prospective, multicentre cohort aiming to evaluate the long-term outcomes of EVD survivors infected during the 2014-15 outbreak in Guinea. Of the 216 participants enrolled in the study in October 2015, 44 patients with arthralgia/myalgia underwent a physical examination by a rheumatologist (the Eborheum cohort)...
March 22, 2017: Rheumatology
https://www.readbyqxmd.com/read/28369946/does-exercise-increase-or-decrease-pain-central-mechanisms-underlying-these-two-phenomena
#9
Lucas V Lima, Thiago S S Abner, Kathleen A Sluka
Exercise is an integral part of the rehabilitation of patients suffering a variety of chronic musculoskeletal conditions, such as fibromyalgia, chronic low back pain and myofascial pain. Regular physical activity is recommended for treatment of chronic pain and its effectiveness has been established in clinical trials for people with a variety of pain conditions. However, exercise can also increase pain making participation in rehabilitation challenging for the person with pain. Animal models of exercise-induced pain have been developed and point to central mechanisms underlying this phenomena, such as increased activation of NMDA receptors in pain-modulating areas...
March 29, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28369107/mapping-the-association-between-back-pain-and-type-2-diabetes-a-cross-sectional-and-longitudinal-study-of-adult-spanish-twins
#10
Amabile Dario, Manuela Ferreira, Kathryn Refshauge, Alison Harmer, Juan Sánchez-Romera, Francisco Pérez-Riquelme, Ligia Cisneros, Juan Ordoñana, Paulo Ferreira
BACKGROUND: Back pain and type 2 diabetes often co-occur, resulting in greater impact on people's health and complexity in their care. Plausible causal mechanisms for this association have been proposed, yet the nature of the link remains unclear. We therefore explored the direction of the association between type 2 diabetes and chronic back pain in twins, controlling for genetics and early environmental confounding. METHODS: 2,096 and 1,098 twins were included in the cross-sectional and longitudinal analyses, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28368984/degenerative-spondylolisthesis-is-related-to-multiparity-and-hysterectomies-in-older-women
#11
Jacek Cholewicki, Angela S Lee, John M Popovich, Lawrence W Mysliwiec, Michael D Winkelpleck, John N Flood, Pramod K Pathak, Kiilani H Kaaikala, N Peter Reeves, Ralph Kothe
STUDY DESIGN: A case-control study OBJECTIVE.: To determine whether parity and abdominal surgeries are associated with degenerative spondylolisthesis (DS). SUMMARY OF BACKGROUND DATA: DS is considered to be a major cause of low back pain (LBP) in the older population, with greater prevalence of DS among women. Because LBP and impaired abdominal muscle function are common during pregnancy and post-partum, parity-related abdominal muscle deficiency, resulting in poor spinal mechanics, could be a factor in the development of DS in women...
March 31, 2017: Spine
https://www.readbyqxmd.com/read/28365848/attenuation-of-cortical-activity-triggering-descending-pain-inhibition-in-chronic-low-back-pain-patients-a-functional-magnetic-resonance-imaging-study
#12
Yohei Matsuo, Jiro Kurata, Miho Sekiguchi, Katsuhiro Yoshida, Takuya Nikaido, Shin-Ichi Konno
PURPOSE: A considerable portion of chronic low back pain (cLBP) patients lack anatomical abnormality, resist conventional therapeutic interventions, and their symptoms are often complicated with psychological and social factors. Such patients have been reported to show cerebral abnormalities both in anatomy and function by neuroimaging studies. Here we examined differences in cerebral reactivity to a simulated low back pain stimulus between cLBP patients and healthy controls by functional magnetic resonance imaging (fMRI), and their behavioral correlates from a psychophysical questionnaire...
April 1, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28350945/intervertebral-disk-degeneration-and-repair
#13
James Dowdell, Mark Erwin, Theodoe Choma, Alexander Vaccaro, James Iatridis, Samuel K Cho
Intervertebral disk (IVD) degeneration is a natural progression of the aging process. Degenerative disk disease (DDD) is a pathologic condition associated with IVD that has been associated with chronic back pain. There are a variety of different mechanisms of DDD (genetic, mechanical, exposure). Each of these pathways leads to a final common result of unbalancing the anabolic and catabolic environment of the extracellular matrix in favor of catabolism. Attempts have been made to gain an understanding of the process of IVD degeneration with in Vitro studies...
March 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28350240/the-effects-of-task-type-on-time-to-task-failure-during-fatigue-a-modified-s%C3%A3-rensen-test
#14
David W Russ, Andrew J Ross, Brian C Clark, James S Thomas
Understanding mechanisms of fatigue of the trunk extensors is important because fatigue is a major factor in predicting incidence of low back pain, but few studies have examined trunk extensor fatigue muscles using differing load types and measured the amplitude and frequency domain of the electromyographic signal to explain these differences. Sixteen healthy participants performed position- and force-matching fatigue tasks in a modified Sørensen test position. Time to task failure was significantly longer during the position-matching task compared to force-matching task (58...
March 28, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28348505/effects-of-a-pain-catastrophizing-induction-on-sensory-testing-in-women-with-chronic-low-back-pain-a-pilot-study
#15
Chloe J Taub, John A Sturgeon, Kevin A Johnson, Sean C Mackey, Beth D Darnall
Pain catastrophizing, a pattern of negative cognitive-emotional responses to actual or anticipated pain, maintains chronic pain and undermines response to treatments. Currently, precisely how pain catastrophizing influences pain processing is not well understood. In experimental settings, pain catastrophizing has been associated with amplified pain processing. This study sought to clarify pain processing mechanisms via experimental induction of pain catastrophizing. Forty women with chronic low back pain were assigned in blocks to an experimental condition, either a psychologist-led 10-minute pain catastrophizing induction or a control (10-minute rest period)...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/28347933/mechanical-effects-of-traction-on-lumbar-intervertebral-discs-a%C3%A2-magnetic-resonance-imaging-study
#16
Daniel H K Chow, Ernest M K Yuen, L Xiao, Mason C P Leung
BACKGROUND: Although traction has long been used for treating patients with low back pain (LBP), its effects are still inconclusive mainly because of limited high-quality evidence. OBJECTIVE: To provide evidence of the mechanism of traction on lumbar intervertebral discs. DESIGN: A quantitative approach with a repeated measurement protocol. METHOD: Nine participants (mean age = 22.1 ± 0.8 years) without any LBP history were recruited...
March 20, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28344100/facilitated-pro-nociceptive-pain-mechanisms-in-radiating-back-pain-compared-with-localized-back-pain
#17
Henrik Bjarke Vaegter, Thorvaldur Skuli Palsson, Thomas Graven-Nielsen
Facilitated pain mechanisms and impaired pain inhibition are often found in chronic pain patients. This study compared clinical pain profiles, pain sensitivity, as well as pro-nociceptive and anti-nociceptive mechanisms in patients with localized low back pain (n=18), localized neck pain (n=17), low back and radiating leg pain (n=18), or neck and radiating arm pain (n=17). It was hypothesized that patients with radiating pain had facilitated pain mechanisms and impaired pain inhibition compared with localized pain patients...
March 23, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28343048/protective-effect-of-cddo-ea-against-high-glucose-induced-oxidative-injury-via-the-nrf2-ho-1-pathway
#18
Cun-Xin Zhang, Ting Wang, Jin-Feng Ma, Yang Liu, Zheng-Gang Zhou, De-Chun Wang
BACKGROUND CONTEXT: Intervertebral disc degeneration (IDD) is the main cause of low back pain, and nucleus pulposus (NP) cell apoptosis is an important risk factor of IDD. However, the molecular mechanism of this disease remains unknown. PURPOSE: To assess the potential protective effect of CDDO-ethyl amide (EA) against high-glucose-induced oxidative stress injury in NP cells and to investigate the mechanism of antioxidative effects and apoptotic inhibition. STUDY DESIGN/SETTING: To find new molecule to inhibit intervertebral disc degeneration...
March 22, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28323705/etiology-of-adult-onset-stress-fracture-in-the-lumbar-spine
#19
Fumitake Tezuka, Koichi Sairyo, Toshinori Sakai, Akira Dezawa
STUDY DESIGN: This study was a case series. OBJECTIVE: The purpose of this paper was to present a case series of fresh stress fractures (spondylolysis) in the lumbar spines of adult athletes. SUMMARY OF BACKGROUND DATA: Lumbar spondylolysis is a stress fracture of the pars interarticularis, which is generally considered a disease of children or adolescence. There is only 1 case series written in English reporting on adult-onset fresh spondylolysis...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28323240/the-impact-of-continuous-use-of-lumbosacral-orthoses-on-trunk-motor-performance-a-systematic-review-with-meta-analysis
#20
REVIEW
Hiroshi Takasaki, Takahiro Miki
BACKGROUND CONTEXT: Lumbosacral orthosis (LSO) is prescribed by general practitioners for the management of low back pain. It may be speculated that continuous use of an LSO for a prolonged period reduces mechanical loading to the trunk muscle in daily living and results in impairments of the trunk muscle. PURPOSE: This study aims to investigate whether trunk motor performances are impaired by the continuous use of an LSO. STUDY DESIGN/SETTING: This is a systematic review with meta-analysis...
March 18, 2017: Spine Journal: Official Journal of the North American Spine Society
keyword
keyword
54642
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"