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Dynamic Neuromuscular Stabilization

Jayden A Clark, Elise J Yeaman, Catherine A Blizzard, Jyoti A Chuckowree, Tracey C Dickson
Amyotrophic lateral sclerosis (ALS) is an aggressive multifactorial disease converging on a common pathology: the degeneration of motor neurons (MNs), their axons and neuromuscular synapses. This vulnerability and dysfunction of MNs highlights the dependency of these large cells on their intracellular machinery. Neuronal microtubules (MTs) are intracellular structures that facilitate a myriad of vital neuronal functions, including activity dependent axonal transport. In ALS, it is becoming increasingly apparent that MTs are likely to be a critical component of this disease...
2016: Frontiers in Cellular Neuroscience
Garrett S Bullock Spt, Nate Brookerson, Amy M Knab, Robert J Butler
Abnormal fundamental movement patterns and upper quarter dynamic balance are proposed mechanisms affecting athletic performance and injury risk. There are few studies investigating functional movement and closed chain upper extremity dynamic stability in swimmers. The purpose of this study was to determine differences in fundamental movement competency and closed chain upper extremity dynamic balance, utilizing the Functional Movement Screen (FMS) and Upper Quarter Y-Balance Test (YBT-UQ), of high school (HS; n=70) and collegiate (COL; n=70) swimmers...
September 16, 2016: Journal of Strength and Conditioning Research
Taegyu Kim, Eunkuk Kim, Hokyung Choi
OBJECTIVE: To determine whether a neuromuscular rehabilitation program can improve postural stability, and ankle evertor strength, and to examine the temporal changes and persistence of the rehabilitation effects in athletes with chronic ankle instability (CAI). DESIGN: A total of 21 national women's field hockey players participated in this study (CAI, n = 12; control, n = 9). Main outcome measures included isokinetic ankle evertor strength (peak torque, PT; total work, TW) at 30°/s, 60°/s, 90°/s and 120°/s, mediolateral stability index (MSI), and dynamic stability test (TCT)...
August 24, 2016: Journal of Sport Rehabilitation
Amanda Buyan, Antreas C Kalli, Mark S P Sansom
Dok7 is a peripheral membrane protein that is associated with the MuSK receptor tyrosine kinase. Formation of the Dok7/MuSK/membrane complex is required for the activation of MuSK. This is a key step in the complex exchange of signals between neuron and muscle, which lead to neuromuscular junction formation, dysfunction of which is associated with congenital myasthenic syndromes. The Dok7 structure consists of a Pleckstrin Homology (PH) domain and a Phosphotyrosine Binding (PTB) domain. The mechanism of the Dok7 association with the membrane remains largely unknown...
July 2016: PLoS Computational Biology
Susan T Tran, Staci Thomas, Christopher DiCesare, Megan Pfeiffer, Soumitri Sil, Tracy V Ting, Sara E Williams, Gregory D Myer, Susmita Kashikar-Zuck
BACKGROUND: Adolescents with juvenile fibromyalgia (JFM) tend to be very sedentary and avoid participation in physical activity. A prior study suggested that JFM patients show altered biomechanics compared to healthy adolescents which may make them more prone to pain/injury during exercise. A new intervention combining well established cognitive behavioral therapy (CBT) techniques with specialized neuromuscular exercise -Fibromyalgia Integrative Training for Teens (FIT Teens) was developed and shown to be promising in improving functioning in adolescents with JFM...
2016: Pediatric Rheumatology Online Journal
D Gunasekaran, J Sridhar, V Suryanarayanan, N C Manimaran, Sanjeev Kumar Singh
Nicotinic acetylcholine receptors (nAChRs) are neuromuscular proteins responsible for muscle contraction upon binding with chemical stimulant acetylcholine (ACh). The α-neurotoxins of snake mimic the structure of ACh and attacks nAChRs, which block the flow of ACh and leads to numbness and paralysis. The toxin-binding site of alpha subunit in the nAChRs is highly conserved throughout chordate lineages with few exceptions in resistance organisms. In this study, we have analyzed the sequence and structures of toxin-binding/resistant nAChRs and their interaction stability with toxins through molecular docking and molecular dynamics simulation (MDS)...
July 15, 2016: Journal of Biomolecular Structure & Dynamics
Edwenia O'Malley, John C Murphy, Ulrik McCarthy Persson, Conor Gissane, Catherine Blake
Team-based neuromuscular training programs for injury prevention have been tested primarily in female and adolescent athletes in soccer, handball and basketball, with limited research in adult male field sports. This study explored whether the GAA 15, a multifaceted 8-week neuromuscular training program could improve risk factors for lower limb injury in male Gaelic footballers and hurlers. Four Gaelic sports collegiate teams were randomized into intervention or control groups. Two teams, one football, one hurling, (n=41), were allocated to the intervention, undertaking a 15 minute program of neuromuscular training exercises at the start of team training sessions, twice weekly for 8 weeks...
July 7, 2016: Journal of Strength and Conditioning Research
F V Harding, Kenneth Mengel
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Taegyu Kim, Eunkuk Kim, Hokyung Cho
OBJECTIVE: To determine whether a neuromuscular rehabilitation program can improve postural stability, and ankle evertor strength, and to examine the temporal changes and persistence of the rehabilitation effects in athletes with chronic ankle instability (CAI). DESIGN: A total of 21 national women's field hockey players participated in this study (CAI, n = 12; control, n = 9). Main outcome measures included isokinetic ankle evertor strength (peak torque, PT; total work, TW) at 30°/s, 60°/s, 90°/s and 120°/s, mediolateral stability index (MSI), and dynamic stability test (TCT)...
June 14, 2016: Journal of Sport Rehabilitation
Katelyn F Allison, Timothy C Sell, Anne Benjaminse, Scott M Lephart
CONTEXT: Knee injuries commonly occur in later stages of competition, indicating that fatigue may influence dynamic knee stability. Force sense (FS) is a submodality of proprioception influenced by muscle mechanoreceptors, which, if negatively affected by fatigue, may result in less-effective neuromuscular control. OBJECTIVES: To determine the effects of peripheral fatigue on FS of the quadriceps and hamstrings. DESIGN: Quasi-experimental study design...
May 2016: Journal of Sport Rehabilitation
Dennis Hamacher, Alexander Törpel, Daniel Hamacher, Lutz Schega
Fatigue directly affects key features of the sensorimotor system which disorganizes voluntary control of movement accuracy. Local dynamic stability of walking is considered a sensitive measure for neuromuscular performance. To gain greater insight in the role of fatigue in motor behaviour in older and young adults during walking, the current experiment analyses gait patterns of healthy young but maximal fatigued individuals and gait patterns in submaximal fatigued older adults. Ten young and 18 older subjects performed a bicycle incremental exercise test on a cycle ergometer...
July 2016: Gait & Posture
F Ehsani, A M Arab, M Salavati, S Jaberzadeh, A Hajihasani
BACKGROUND: Ultrasound (US) imaging can be used for the measurement of trunk muscle activity. However, the displacements of US transducer, especially during more dynamic situations, may disturb the measurement results. To control this variable, some studies used transducer fixator (TF), but no study evaluated the effect of using TF on US reliability in dynamic situations. The present study discriminated this issue. OBJECTIVE: To investigate the intra-session and inter-session reliability of lateral abdominal muscle thickness measurement in dynamic standing postural tasks using US with and without TF in participants with and without chronic low back pain (CLBP)...
May 19, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Ram Haddas, James Yang, Isador Lieberman
PURPOSE: To examine the influence of volitional preemptive abdominal contraction (VPAC) and recurrent low back pain (rLBP) on trunk mechanics and neuromuscular control during a symmetric lifting task. METHODS: A 2 × 2 crossover mixed design was used to examine the effects of VPAC and group. Thirty-seven healthy individuals and 32 rLBP individuals performed symmetric box lifting trials with and without VPAC to a 1-m height table 3D trunk, pelvis, and hip joint angle and electromyographic magnitude variables were obtained...
September 2016: European Spine Journal
Ana Antunes, Filomena Carnide, Ricardo Matias
Emerging evidence suggests that scapular-focused therapeutic exercises hold promise for shoulder dynamic stability retraining. While recent findings show that therapeutic exercises can alter scapular neuromuscular function measured with muscle electromyography, no study has yet addressed the effects of kinematic biofeedback for improving scapulothoracic control and performance. The aim of this study was to assess the effectiveness of kinematic biofeedback on motor relearning transfer during shoulder flexion and a daily activity, on the quality of scapular-focused exercise performance, and on execution time...
August 2016: Human Movement Science
Shawn M Beaudette, Katelyn J Larson, Dennis J Larson, Stephen H M Brown
The purpose of the current work was to (1) determine whether low back cutaneous sensitivity could be reduced through the use of a topical lidocaine-prilocaine anesthetic (EMLA(®)) to mirror reductions reported in chronic lower back pain (CLBP) patients, as well as to (2) identify whether reductions in cutaneous sensitivity resulted in decreased lumbar spine proprioception, neuromuscular control and dynamic stability. Twenty-eight healthy participants were divided equally into matched EMLA and PLACEBO treatment groups...
August 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Hyunglae Lee, Neville Hogan
Understanding the passive or non-passive behavior of the neuro-muscular system is important to design and control robots that physically interact with humans, since it provides quantitative information to secure coupled stability while maximizing performance. This has become more important than ever apace with the increasing demand for robotic technologies in neurorehabilitation. This paper presents a quantitative characterization of passive and non-passive behavior of the ankle of young healthy subjects, which provides a baseline for future studies in persons with neurological impairments and informs future developments of rehabilitation robots, such as exo-skeletal devices and powered prostheses...
March 10, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
Daniel J Southwell, Nicole F Hills, Linda McLean, Ryan B Graham
BACKGROUND: Targeted activation of the transversus abdominis (TrA) muscle through the abdominal drawing-in maneuver (ADIM) is a frequently prescribed exercise for the prevention and rehabilitation of low back pain. However, there is still debate over the role the ADIM plays in maintaining a stable spine during movement. Thus, a single cohort pre/post-intervention protocol was used to examine whether 5 min of ADIM training prior to a dynamic movement task alters dynamic spine stability and control...
2016: Journal of Neuroengineering and Rehabilitation
Nejc Sarabon, Stefan Löfler, Gabriella Hosszu, Christian Hofer
Consequences of falls are a major health problem in elderly. Poor balance is the precursor of falls and balance impairment has been evidenced after an injury. On the other hand, balance and stability can be improved with training. At the beginning of the project Mobility in Aging one of the questions was how to measure dynamic and static balance in order to get reliable and sensitive parameters to follow the effect of decay in movement functions in elderly or to track the improvement after training. In this short report we will give a couple of answers to a long standing debate...
August 24, 2015: European Journal of Translational Myology
I Faizullin, E Faizullina
BACKGROUND: Ankle sprain is a medical condition when ankle ligaments are totally or partially torn. The primary cause of ankle sprain is sharp movements like turning or rolling the foot [1]. The ankle sprain needs to be treated right after the trauma, because if not treated it could lead to decreased stability of the ankle joint and lead to chronic ankle instability, which is characterized by increased risk of the ankle sprain [2] . We suppose that rehabilitation after the ankle sprain could significantly increase the performance of sportsmen...
2015: International Journal of Risk & Safety in Medicine
Simon Lee, David D Savin, Neal R Shah, Daniel Bronsnick, Benjamin Goldberg
Scapular winging is a rare, underreported, and debilitating disorder that produces abnormal scapulothoracic kinematics, which can lead to shoulder weakness, decreased range of motion, and substantial pain. Although there are numerous underlying etiologies, injuries to the long thoracic nerve or spinal accessory nerve are the most common, with resultant neuromuscular imbalance in the scapulothoracic stabilizing muscles. Early diagnosis followed by initiation of a treatment algorithm is important for successful outcomes...
October 21, 2015: Journal of Bone and Joint Surgery. American Volume
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