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Danijela Vojta, Eva Marie Karlsen, Jens Spanget-Larsen
Myricetin (3,3',4',5,5',7'-hexahydroxyflavone) was investigated by linear dichroism spectroscopy on molecular samples partially aligned in stretched poly(vinyl alcohol) (PVA). At least five electronic transitions in the range 40,000-20,000cm(-1) were characterized with respect to their wavenumbers, relative intensities, and transition moment directions. The observed bands were assigned to electronic transitions predicted with TD-B3LYP/6-31+G(d,p).
September 13, 2016: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Hatem Barghathi, Thomas Vojta, José A Hoyos
We investigate the influence of time-varying environmental noise, i.e., temporal disorder, on the nonequilibrium phase transition of the contact process. Combining a real-time renormalization group, scaling theory, and large scale Monte-Carlo simulations in one and two dimensions, we show that the temporal disorder gives rise to an exotic critical point. At criticality, the effective noise amplitude diverges with increasing time scale, and the probability distribution of the density becomes infinitely broad, even on a logarithmic scale...
August 2016: Physical Review. E
Jitka Bečanová, Lisa Melymuk, Šimon Vojta, Klára Komprdová, Jana Klánová
Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are a large group of important chemical compounds with unique and useful physico-chemical properties, widely produced and used in many applications. However, due to the toxicity, bioaccumulation and long-range transport potential of certain PFASs, they are of significant concern to scientists and policy makers. To assess human exposure to PFASs, it is necessary to understand the concentrations of these emerging contaminants in our environment, and particularly environments where urban population spend most of their time, i...
December 2016: Chemosphere
Wojciech Kiebzak, Arkadiusz Żurawski, Michał Dwornik
BACKGROUND: Developmental dysplasia of the hip joint is one of the most common congenital defects and often results in functional and structural disorders. Such cases particularly demand optimizing therapeutic effects and maximally reducing the duration of therapy. PURPOSE: The aim of this case report is to present the therapeutic process in a child with developmental hip dysplasia. CASE REPORT: This is a case report of a female child with a birth weight of 2,800 g and an Apgar score of 9 points born to a gravida 3 para 3 mother at 37 weeks...
2016: Therapeutics and Clinical Risk Management
Matthias Vojta, Andrew K Mitchell, Fabian Zschocke
Kitaev's honeycomb-lattice compass model describes a spin liquid with emergent fractionalized excitations. Here, we study the physics of isolated magnetic impurities coupled to the Kitaev spin-liquid host. We reformulate this Kondo-type problem in terms of a many-state quantum impurity coupled to a multichannel bath of Majorana fermions and present the numerically exact solution using Wilson's numerical renormalization group technique. Quantum phase transitions occur as a function of Kondo coupling and locally applied field...
July 15, 2016: Physical Review Letters
Reginald O'Hara, Christopher Vojta, Amy Henry, Lydia Caldwell, Molly Wade, Stacie Swanton, Jon K Linderman, Jason Ordway
INTRODUCTION: Heat-related illness is a critical factor for military personnel operating in hyperthermic environments. Heat illness can alter cognitive and physical performance during sustained operations missions. Therefore, the primary purpose of this investigation was to determine the effects of a novel cooling shirt on core body temperature in highly trained US Air Force personnel. METHODS: Twelve trained (at least 80th percentile for aerobic fitness according to the American College of Sports Medicine, at least 90% on the US Air Force fitness test), male Air Force participants (mean values: age, 25 ± 2...
2016: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
Lisa Melymuk, Pernilla Bohlin-Nizzetto, Petr Kukučka, Šimon Vojta, Jiří Kalina, Pavel Čupr, Jana Klánová
This study is a systematic assessment of different houses and apartments, their ages and renovation status, indoors and outdoors, and in summer vs. winter, with a goal of bringing some insight into the major sources of semivolatile organic compounds (SVOCs) and their variability. Indoor and outdoor air concentrations of polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs) and novel flame retardants (NFRs) were determined at 17-20 homes in Czech Republic in winter and summer. Indoor concentrations were consistently higher than outdoor concentrations for all compounds; indoor/outdoor ratios ranged from 2-20, with larger differences for the current use NFRs than for legacy PCBs...
July 15, 2016: Environmental Pollution
Filip Kokáš, Petr Vojta, Petr Galuszka
Barley (Hordeum vulgare) is an economically important species, which can be cultivated in environmentally adverse conditions due to its higher tolerance in contrast to other cereal crops. The draft of H. vulgare genome is available already for couple of years; however its functional annotation is still incomplete. All available databases were searched to expand current annotation. The improved annotation was used to describe processes and genes regulated in transgenic lines showing higher tolerance to drought in our associated article, doi:10...
September 2016: Data in Brief
G Denise Hammond, Adam L Vojta, Sheila A Grant, Heather K Hunt
The creation of label-free biosensors capable of accurately detecting trace contaminants, particularly small organic molecules, is of significant interest for applications in environmental monitoring. This is achieved by pairing a high-sensitivity signal transducer with a biorecognition element that imparts selectivity towards the compound of interest. However, many environmental pollutants do not have corresponding biorecognition elements. Fortunately, biomimetic chemistries, such as molecular imprinting, allow for the design of artificial receptors with very high selectivity for the target...
2016: Biosensors
Pavlína Karásková, Marta Venier, Lisa Melymuk, Jitka Bečanová, Šimon Vojta, Roman Prokeš, Miriam L Diamond, Jana Klánová
Concentrations of 20 perfluorinated alkyl substances (PFASs) were measured in dust samples from 41 homes in Canada, the Czech Republic, and United States in the spring-summer of 2013. The most frequently detected compounds were perfluorohexanoic acid (PFHxA) and perfluorooctane sulfonate (PFOS). PFOS and perfluorooctanoic acid (PFOA) had the highest concentrations of PFASs in all countries. PFOS median concentrations for the three countries were between 9.1 and 14.1ng/g, and PFOA medians ranged between 8.2 and 9...
September 2016: Environment International
Marta Venier, Ondřej Audy, Šimon Vojta, Jitka Bečanová, Kevin Romanak, Lisa Melymuk, Martina Krátká, Petr Kukučka, Joseph Okeme, Amandeep Saini, Miriam L Diamond, Jana Klánová
Concentrations of more than 20 brominated flame retardants (FRs), including polybrominated diphenyl ethers (PBDEs) and emerging FRs, were measured in air, dust and window wipes from 63 homes in Canada, the Czech Republic and the United States in the spring and summer of 2013. Among the PBDEs, the highest concentrations were generally BDE-209 in all three matrices, followed by Penta-BDEs. Among alternative FRs, EHTBB and BEHTBP were detected at the highest concentrations. DBDPE was also a major alternative FR detected in dust and air...
September 2016: Environment International
Stephan Rachel, Lars Fritz, Matthias Vojta
Majorana fermions, originally proposed as elementary particles acting as their own antiparticles, can be realized in condensed-matter systems as emergent quasiparticles, a situation often accompanied by topological order. Here we propose a physical system which realizes Landau levels-highly degenerate single-particle states usually resulting from an orbital magnetic field acting on charged particles-for Majorana fermions. This is achieved in a variant of a quantum spin system due to Kitaev which is distorted by triaxial strain...
April 22, 2016: Physical Review Letters
Thomas Vojta, Ronald Dickman
We investigate how a clean continuous phase transition is affected by spatiotemporal disorder, i.e., by an external perturbation that fluctuates in both space and time. We derive a generalization of the Harris criterion for the stability of the clean critical behavior in terms of the space-time correlation function of the external perturbation. As an application, we consider diffusive disorder, i.e., an external perturbation governed by diffusive dynamics, and its effects on a variety of equilibrium and nonequilibrium critical points...
March 2016: Physical Review. E
Marija Klasić, Jasminka Krištić, Petra Korać, Tomislav Horvat, Dora Markulin, Aleksandar Vojta, Karli R Reiding, Manfred Wuhrer, Gordan Lauc, Vlatka Zoldoš
Changes in N-glycosylation of plasma proteins are observed in many types of cancer, nevertheless, few studies suggest the exact mechanism involved in aberrant protein glycosylation. Here we studied the impact of DNA methylation on the N-glycome in the secretome of the HepG2 cell line derived from hepatocellular carcinoma (HCC). Since the majority of plasma glycoproteins originate from the liver, the HepG2 cells represent a good model for glycosylation changes in HCC that are detectable in blood, which is an easily accessible analytic material in a clinical setting...
2016: Scientific Reports
Lisa Melymuk, Pernilla Bohlin-Nizzetto, Šimon Vojta, Martina Krátká, Petr Kukučka, Ondřej Audy, Petra Přibylová, Jana Klánová
Seven types of indoor samples, covering five indoor matrices, were collected in a residential room, and analyzed for five classes of semivolatile organic compounds (SVOCs). The goal was to improve the understanding of the relationship between indoor air, surface films and dust, based on differences in sources, physicochemical properties, and indoor environmental characteristics. Comparisons of the five matrices (gas- and particle-phase air, floor dust, surface dust/films and window films) demonstrated that within our test room a semi-quantitative measurement of the SVOC distributions and concentrations could be obtained by air, and composite dust or furniture surface wipes...
June 2016: Chemosphere
Hatem Barghathi, Thomas Vojta
We investigate the behavior of nonequilibrium phase transitions under the influence of disorder that locally breaks the symmetry between two symmetrical macroscopic absorbing states. In equilibrium systems such "random-field" disorder destroys the phase transition in low dimensions by preventing spontaneous symmetry breaking. In contrast, we show here that random-field disorder fails to destroy the nonequilibrium phase transition of the one- and two-dimensional generalized contact process. Instead, it modifies the dynamics in the symmetry-broken phase...
February 2016: Physical Review. E
Lea Vojta, Hrvoje Fulgosi
In photosynthesis, the flavoenzyme ferredoxin:NADP(+) oxidoreductase (FNR) catalyses the final electron transfer from ferredoxin to NADP(+), which is considered as the main pathway of high-energy electron partitioning in chloroplasts (DOI: 10.1111/j.1365-313X.2009.03999.x[1], DOI: 10.1038/srep10085[2]). Different detergents and pH treatments of photosynthetic membranes isolated from the Arabidopsis wild-type (WT) and the loss-of-function mutants of the thylakoid rhodanase-like protein TROL (trol), pre-acclimated to either dark, growth-light, or high-light conditions, were used to probe the strength of FNR-membrane associations...
June 2016: Data in Brief
Aleksandar Vojta, Paula Dobrinić, Vanja Tadić, Luka Bočkor, Petra Korać, Boris Julg, Marija Klasić, Vlatka Zoldoš
Epigenetic studies relied so far on correlations between epigenetic marks and gene expression pattern. Technologies developed for epigenome editing now enable direct study of functional relevance of precise epigenetic modifications and gene regulation. The reversible nature of epigenetic modifications, including DNA methylation, has been already exploited in cancer therapy for remodeling the aberrant epigenetic landscape. However, this was achieved non-selectively using epigenetic inhibitors. Epigenetic editing at specific loci represents a novel approach that might selectively and heritably alter gene expression...
July 8, 2016: Nucleic Acids Research
L I Igel, A Sinha, K H Saunders, C M Apovian, D Vojta, L J Aronne
Metformin is not currently used for weight loss or diabetes prevention because it lacks an FDA indication for obesity and/or pre-diabetes treatment. Based on the evidence, metformin has been shown to decrease the incidence of type 2 diabetes, and compares favorably to other weight-loss medications in terms of efficacy as well as safety. Thus, metformin should be considered for a treatment indication in patients with these conditions.
April 2016: Current Atherosclerosis Reports
Petr Vojta, Filip Kokáš, Alexandra Husičková, Jiří Grúz, Veronique Bergougnoux, Cintia F Marchetti, Eva Jiskrová, Eliška Ježilová, Václav Mik, Yoshihisa Ikeda, Petr Galuszka
Cytokinin plant hormones have been shown to play an important role in plant response to abiotic stresses. Herein, we expand upon the findings of Pospíšilová et al. [30] regarding preparation of novel transgenic barley lines overexpressing cytokinin dehydrogenase 1 gene from Arabidopsis under the control of mild root-specific promotor of maize β-glycosidase. These lines showed drought-tolerant phenotype mainly due to alteration of root architecture and stronger lignification of root tissue. A detailed transcriptomic analysis of roots of transgenic plants subjected to revitalization after drought stress revealed attenuated response through the HvHK3 cytokinin receptor and up-regulation of two transcription factors implicated in stress responses and abscisic acid sensitivity...
September 25, 2016: New Biotechnology
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