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https://www.readbyqxmd.com/read/29778940/pcbs-and-organochlorine-pesticides-in-indoor-environments-a-comparison-of-indoor-contamination-in-canada-and-czech-republic
#1
Ondrej Audy, Lisa Melymuk, Marta Venier, Simon Vojta, Jitka Becanova, Kevin Romanak, Martina Vykoukalova, Roman Prokes, Petr Kukucka, Miriam L Diamond, Jana Klanova
Polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) are restricted compounds that are ubiquitously detected in the environment, including indoor matrices such as air and residential dust. We report concentrations of PCBs and selected OCPs in indoor air and dust from homes in Canada (23 homes) and Czech Republic (20 homes). Indoor air concentrations of PCBs and OCPs were ∼10 times higher than that outdoors. PCB concentrations of ∼450 ng/m3 were similar in both countries, higher in homes built before the restrictions on PCBs, and had congener profiles consistent with PCB mixtures manufactured or used in each country...
May 3, 2018: Chemosphere
https://www.readbyqxmd.com/read/29758131/the-outer-membrane-omp85-like-protein-p39-influences-metabolic-homeostasis-in-mature-arabidopsis-thaliana
#2
Yi-Ching Hsueh, Kerstin Nicolaisen, Lucia E Gross, Joachim Nöthen, Nicolas Schauer, Lea Vojta, Franziska Ertel, Ina Koch, Roman Ladig, Hrvoje Fulgosi, Alisdair R Fernie, Enrico Schleiff
Omp85 proteins form a large membrane protein family found in bacteria and eukaryotes. Omp85 proteins are composed of a C-terminal β-barrel-shaped membrane domain and one, or more, N-terminal polypeptide-transport-associated (POTRA) domain(s). However, Arabidopsis thaliana contains two genes coding for Omp85 proteins without POTRA domain. One gene is designated P39, according to the molecular weight of the encoded protein. The protein is targeted to plastids and it was established that p39 shows electrophysiological properties similar to the other Omp85 family members, particularly to the one designated Toc75V/Oep80...
May 14, 2018: Plant Biology
https://www.readbyqxmd.com/read/29734094/small-scale-spatial-variability-of-flame-retardants-in-indoor-dust-and-implications-for-dust-sampling
#3
Simona Jílková, Lisa Melymuk, Šimon Vojta, Martina Vykoukalová, Pernilla Bohlin-Nizzetto, Jana Klánová
Indoor dust is often used to evaluate levels of organic compounds indoors, particularly for compounds with indoor sources, such as flame retardants (FRs). Yet there are uncertainties about the type of information that can be obtained from indoor dust. This study reports detailed dust sampling to assess spatial variability in indoor dust concentrations, the relationship between FR sources and dust, and the implications when interpreting dust concentrations. Multiple dust samples were collected from a range of surface types in three large rooms: a residential flat, a university seminar room, and a university computer room...
April 23, 2018: Chemosphere
https://www.readbyqxmd.com/read/29602437/a-computer-vision-based-system-for-monitoring-vojta-therapy
#4
Muhammad Hassan Khan, Julien Helsper, Muhammad Shahid Farid, Marcin Grzegorzek
A neurological illness is t he disorder in human nervous system that can result in various diseases including the motor disabilities. Neurological disorders may affect the motor neurons, which are associated with skeletal muscles and control the body movement. Consequently, they introduce some diseases in the human e.g. cerebral palsy, spinal scoliosis, peripheral paralysis of arms/legs, hip joint dysplasia and various myopathies. Vojta therapy is considered a useful technique to treat the motor disabilities...
May 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29595683/mapping-the-human-brain-during-a-specific-vojta-s-tactile-input-the-ipsilateral-putamen-s-role
#5
Ismael Sanz-Esteban, Cesar Calvo-Lobo, Marcos Ríos-Lago, Juan Álvarez-Linera, Daniel Muñoz-García, David Rodríguez-Sanz
A century of research in human brain parcellation has demonstrated that different brain areas are associated with functional tasks. New neuroscientist perspectives to achieve the parcellation of the human brain have been developed to know the brain areas activation and its relationship with different stimuli. This descriptive study aimed to compare brain regions activation by specific tactile input (STI) stimuli according to the Vojta protocol (STI-group) to a non-STI stimulation (non-STI-group). An exploratory functional magnetic resonance imaging (fMRI) study was performed...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29548254/two-dimensional-ising-model-on-random-lattices-with-constant-coordination-number
#6
Manuel Schrauth, Julian A J Richter, Jefferson S E Portela
We study the two-dimensional Ising model on networks with quenched topological (connectivity) disorder. In particular, we construct random lattices of constant coordination number and perform large-scale Monte Carlo simulations in order to obtain critical exponents using finite-size scaling relations. We find disorder-dependent effective critical exponents, similar to diluted models, showing thus no clear universal behavior. Considering the very recent results for the two-dimensional Ising model on proximity graphs and the coordination number correlation analysis suggested by Barghathi and Vojta [Phys...
February 2018: Physical Review. E
https://www.readbyqxmd.com/read/29548098/fractional-brownian-motion-with-a-reflecting-wall
#7
Alexander H O Wada, Thomas Vojta
Fractional Brownian motion, a stochastic process with long-time correlations between its increments, is a prototypical model for anomalous diffusion. We analyze fractional Brownian motion in the presence of a reflecting wall by means of Monte Carlo simulations. Whereas the mean-square displacement of the particle shows the expected anomalous diffusion behavior 〈x^{2}〉∼t^{α}, the interplay between the geometric confinement and the long-time memory leads to a highly non-Gaussian probability density function with a power-law singularity at the barrier...
February 2018: Physical Review. E
https://www.readbyqxmd.com/read/29547304/cluster-glass-phase-in-pyrochlore-xy-antiferromagnets-with-quenched-disorder
#8
Eric C Andrade, José A Hoyos, Stephan Rachel, Matthias Vojta
We study the impact of quenched disorder (random exchange couplings or site dilution) on easy-plane pyrochlore antiferromagnets. In the clean system, order by disorder selects a magnetically ordered state from a classically degenerate manifold. In the presence of randomness, however, different orders can be chosen locally depending on details of the disorder configuration. Using a combination of analytical considerations and classical Monte Carlo simulations, we argue that any long-range-ordered magnetic state is destroyed beyond a critical level of randomness where the system breaks into magnetic domains due to random exchange anisotropies, becoming, therefore, a glass of spin clusters, in accordance with the available experimental data...
March 2, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29542447/frustration-and-quantum-criticality
#9
Matthias Vojta
This review article is devoted to the interplay between frustrated magnetism and quantum critical phenomena, covering both theoretical concepts and ideas as well as recent experimental developments in correlated-electron materials. The first part deals with local-moment magnetism in Mott insulators and the second part with frustration in metallic systems. In both cases, frustration can either induce exotic phases accompanied by exotic quantum critical points or lead to conventional ordering with unconventional crossover phenomena...
March 15, 2018: Reports on Progress in Physics
https://www.readbyqxmd.com/read/29526810/integrated-physical-map-of-bread-wheat-chromosome-arm-7ds-to-facilitate-gene-cloning-and-comparative-studies
#10
Zuzana Tulpová, Ming-Cheng Luo, Helena Toegelová, Paul Visendi, Satomi Hayashi, Petr Vojta, Etienne Paux, Andrzej Kilian, Michaël Abrouk, Jan Bartoš, Marián Hajdúch, Jacqueline Batley, David Edwards, Jaroslav Doležel, Hana Šimková
Bread wheat (Triticum aestivum L.) is a staple food for a significant part of the world's population. The growing demand on its production can be satisfied by improving yield and resistance to biotic and abiotic stress. Knowledge of the genome sequence would aid in discovering genes and QTLs underlying these traits and provide a basis for genomics-assisted breeding. Physical maps and BAC clones associated with them have been valuable resources from which to generate a reference genome of bread wheat and to assist map-based gene cloning...
March 8, 2018: New Biotechnology
https://www.readbyqxmd.com/read/29469136/acute-lymphoblastic-leukemia-in-a-child-with-leri-weill-syndrome-and-complete-shox-gene-deletion-a-case-report
#11
Jana Volejnikova, Jirina Zapletalova, Marie Jarosova, Helena Urbankova, Vojta Petr, Eva Klaskova, Marshall S Horwitz, Marian Hajduch, Vladimir Mihal
BACKGROUND: Leri-Weill syndrome (LWS) ranks among conditions with short stature homeobox gene (SHOX) haploinsufficiency. Data on possible association of SHOX aberrations with malignant diseases are scarce. METHODS AND RESULTS: We report a unique case of an 8-year-old girl who was successfully treated for acute lymphoblastic leukemia (pre-B ALL, intermediate risk) and was subsequently diagnosed with LWS due to characteristic clinical appearance (short disproportionate stature, Madelung deformity of the wrist) and molecular genetic examination (complete deletion of SHOX)...
March 2018: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/29464831/intensive-remote-monitoring-versus-conventional-care-in-type-1-diabetes-a-randomized-controlled-trial
#12
Laura Gandrud, Aylin Altan, Paul Buzinec, Jesse Hemphill, Jayne Chatterton, Tina Kelley, Deneen Vojta
OBJECTIVE: While frequent contact with diabetes care providers may improve glycemic control among patients with type 1 diabetes (T1D), in-person visits are labor-intensive and costly. This study was conducted to assess the impact of an intensive remote therapy (IRT) intervention for pediatric patients with T1D. METHODS: Pediatric patients with T1D were randomized to IRT or conventional care (CC) for 6 months. Both cohorts continued routine quarterly clinic visits and uploaded device data; for the IRT cohort, data were reviewed and patients were contacted if regimen adjustments were indicated...
February 21, 2018: Pediatric Diabetes
https://www.readbyqxmd.com/read/29455155/newly-designed-11-gene-panel-reveals-first-case-of-hereditary-amyloidosis-captured-by-massive-parallel-sequencing
#13
Zuzana Chyra Kufova, Tereza Sevcikova, Jaroslav Januska, Petr Vojta, Arpad Boday, Pavla Vanickova, Jana Filipova, Katerina Growkova, Tomas Jelinek, Marian Hajduch, Roman Hajek
AIMS: Amyloidosis is caused by deposition of abnormal protein fibrils, leading to damage of organ function. Hereditary amyloidosis represents a monogenic disease caused by germline mutations in 11 amyloidogenic precursor protein genes. One of the important but non-specific symptoms of amyloidosis is hypertrophic cardiomyopathy. Diagnostics of hereditary amyloidosis is complicated and the real cause can remain overlooked. We aimed to design hereditary amyloidosis gene panel and to introduce new next-generation sequencing (NGS) approach to investigate hereditary amyloidosis in a cohort of patients with hypertrophic cardiomyopathy of unknown significance...
February 17, 2018: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29443882/effects-of-trol-presequence-mutagenesis-on-its-import-and-dual-localization-in-chloroplasts
#14
Lea Vojta, Andrea Čuletić, Hrvoje Fulgosi
Thylakoid rhodanase-like protein (TROL) is involved in the final step of photosynthetic electron transport from ferredoxin to ferredoxin: NADP⁺ oxidoreductase (FNR). TROL is located in two distinct chloroplast compartments-in the inner envelope of chloroplasts, in its precursor form; and in the thylakoid membranes, in its fully processed form. Its role in the inner envelope, as well as the determinants for its differential localization, have not been resolved yet. In this work we created six N-terminal amino acid substitutions surrounding the predicted processing site in the presequence of TROL in order to obtain a construct whose import is affected or localization limited to a single intrachloroplastic site...
February 14, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29342280/epigenetic-differentiation-of-natural-populations-of-lilium-bosniacum-associated-with-contrasting-habitat-conditions
#15
V Zoldoš, I Biruš, E Muratovic, Z Šatovic, A Vojta, O Robin, F Pustahija, F Bogunic, V Vicic Bockor, S Siljak-Yakovlev
Epigenetic variation in natural populations with contrasting habitats might be an important element, in addition to the genetic variation, in plant adaptation to environmental stress. Here, we assessed genetic, epigenetic and cytogenetic structure of the three Lilium bosniacum populations growing on distinct habitats. One population was growing under habitual ecological conditions for this species and the other two were growing under stress associated with high altitude and serpentine soil. Amplified fragment length polymorphism (AFLP) and methylation-sensitive amplification polymorphism (MSAP) analyses revealed that the three populations did not differentiate genetically, but were clearly separated in the three distinct clusters according to DNA methylation profiles...
January 12, 2018: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28910084/changes-in-flame-retardant-and-legacy-contaminant-concentrations-in-indoor-air-during-building-construction-furnishing-and-use
#16
Šimon Vojta, Lisa Melymuk, Jana Klánová
A newly constructed university building was selected for targeted assessment of changes in the levels of flame retardants and legacy contaminants during the installation of building equipment, furniture, electronics, and first year of building use. Indoor air samples were collected during several periods of intensive equipment installation to determine a relationship between newly introduced equipment and changes in the concentrations and profiles of contaminants in indoor air. Samples were analyzed for polybrominated diphenyl ethers (PBDEs), hexabromocyclododecanes (HBCDDs), and new types of flame retardants: brominated (BFRs) and organophosphate esters (OPEs)...
October 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28905230/molecular-detection-of-anaplasma-platys-anaplasma-phagocytophilum-and-wolbachia-sp-but-not-ehrlichia-canis-in-croatian-dogs
#17
Doroteja Huber, Irena Reil, Sanja Duvnjak, Daria Jurković, Damir Lukačević, Miroslav Pilat, Ana Beck, Željko Mihaljević, Lea Vojta, Adam Polkinghorne, Relja Beck
The bacteria Anaplasma platys, Anaplasma phagocytophilum and Ehrlichia canis are tick-borne agents that cause canine vector-borne disease. The prevalence of these pathogens in South Eastern Europe is unknown with the exception of an isolated case of A. platys detected in a dog imported into Germany from Croatia. To gain a better insight into their presence and prevalence, PCR-based screening for these bacterial pathogens was performed on domesticated dogs from different regions of Croatia. Blood samples from 1080 apparently healthy dogs from coastal and continental parts of Croatia as well as tissue samples collected from 63 deceased dogs with a history of anaemia and thrombocytopenia were collected for molecular screening by an Anaplasmataceae-specific 16S rRNA conventional PCR...
November 2017: Parasitology Research
https://www.readbyqxmd.com/read/28903574/whole-exome-sequencing-of-aberrant-plasma-cells-in-a-patient-with-multiple-myeloma-minimal-residual-disease
#18
M Zatopkova, J Filipová, T Jelínek, P Vojta, T Sevcikova, M Simicek, L Rihova, R Bezdekova, K Growkova, Z Kufová, J Smejkalová, M Hajdúch, L Pour, J Minárik, A Jungová, V Maisnar, F Kryukov, R Hájek
Multiple myeloma is a plasma cell dyscrasia. It is the second most common hematological malignancy which is characterized by proliferation of clonal plasma cells producing harmful monoclonal immunoglobulin. Despite treatment modalities greatly evolved during the last decade, small amount of aberrant residual cells reside in patients after therapy and can cause relapse of the disease. Characterization of the residual, resistant clones can help to reveal important therapeutic targets for application of effective and precious treatment...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/28903572/biomarkers-in-immunoglobulin-light-chain-amyloidosis
#19
Z Kufová, T Sevcikova, K Growkova, P Vojta, J Filipová, Z Adam, L Pour, M Penka, R Rysava, P Němec, L Brozova, P Vychytilova, A Jurczyszyn, S Grosicki, A Barchnicka, M Hajdúch, M Simicek, R Hájek
Immunoglobulin light chain amyloidosis (AL amyloidosis - ALA) is a monoclonal gammopathy characterized by presence of aberrant plasma cells producing amyloidogenic immunoglobulin light chains. This leads to formation of amyloid fibrils in various organs and tissues, mainly in heart and kidney, and causes their dysfunction. As amyloid depositing in target organs is irreversible, there is a big effort to identify biomarker that could help to distinguish ALA from other monoclonal gammopathies in the early stages of disease, when amyloid deposits are not fatal yet...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/28871003/association-between-rassf1a-promoter-methylation-and-testicular-germ-cell-tumor-a-meta-analysis-and-a-cohort-study
#20
Dora Markulin, Aleksandar Vojta, Ivana Samaržija, Marija Gamulin, Ivona Bečeheli, Irena Jukić, Čedomir Maglov, Vlatka Zoldoš, Aleksandra Fučić
BACKGROUND: The RAS association domain family protein 1a (RASSF1A) is a prominent tumor suppressor gene showing altered promoter methylation in testicular germ cell tumors (TGCT). RASSF1A promoter hypermethylation might represent an early event in TGCT tumorigenesis. We investigated whether the RASSF1A promoter methylation in peripheral blood of TGCT patients can be associated with testicular cancer risk. MATERIALS AND METHODS: Following a meta-analysis, we performed a cohort study including 32 testicular cancer patients and 32 healthy controls...
September 2017: Cancer Genomics & Proteomics
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