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https://www.readbyqxmd.com/read/26474497/distribution-of-topical-ocular-nepafenac-and-its-active-metabolite-amfenac-to-the-posterior-segment-of-the-eye
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James E Chastain, Mark E Sanders, Michael A Curtis, Nagendra V Chemuturi, Martha E Gadd, Michael A Kapin, Kerry L Markwardt, David C Dahlin
Nepafenac ophthalmic suspensions, 0.1% (NEVANAC(®)) and 0.3% (ILEVRO™), are topical nonsteroidal anti-inflammatory drug (NSAID) products approved in the United States, Europe and various other countries to treat pain and inflammation associated with cataract surgery. NEVANAC is also approved in Europe for the reduction in the risk of postoperative macular edema (ME) associated with cataract surgery in diabetic patients. The efficacy against ME suggests that topical administration leads to distribution of nepafenac or its active metabolite amfenac to the posterior segment of the eye...
April 2016: Experimental Eye Research
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