keyword
https://read.qxmd.com/read/38585500/subclinical-atherosclerosis-in-multiple-sclerosis
#21
JOURNAL ARTICLE
Ruth Ann Marrie, Ronak Patel, Stephen Allan Schaffer
BACKGROUND: People with multiple sclerosis (MS) have an increased risk of ischemic heart disease as compared to people without MS after accounting for traditional vascular risk factors. OBJECTIVE: We assessed whether subclinical atherosclerosis, an inflammatory disease of arteries, occurs in persons with MS who do not have traditional vascular risk factors, and whether the Framingham Score (FRS) predicted carotid intima media thickness (CIMT) similarly in people with and without MS...
2024: Multiple Sclerosis Journal—Experimental, Translational and Clinical
https://read.qxmd.com/read/38582639/subclinical-atherosclerosis-in-young-adults-predicting-cardiovascular-disease-the-cardiovascular-risk-in-young-finns-study
#22
JOURNAL ARTICLE
Olli T Raitakari, Costan G Magnussen, Markus Juonala, Noora Kartiosuo, Katja Pahkala, Suvi Rovio, Juhani S Koskinen, Juha Mykkänen, Tomi P Laitinen, Mika Kähönen, Joel Nuotio, Jorma S A Viikari
BACKGROUND AND AIMS: Atherosclerosis is accompanied by pre-clinical vascular changes that can be detected using ultrasound imaging. We examined the value of such pre-clinical features in identifying young adults who are at risk of developing atherosclerotic cardiovascular disease (ASCVD). METHODS: A total of 2641 individuals free of ASCVD were examined at the mean age of 32 years (range 24-45 years) for carotid artery intima-media thickness (IMT) and carotid plaques, carotid artery elasticity, and brachial artery flow-mediated endothelium-dependent vasodilation (FMD)...
March 19, 2024: Atherosclerosis
https://read.qxmd.com/read/38581738/a-universal-plasma-metabolites-derived-signature-predicts-cardiovascular-disease-risk-in-mafld
#23
JOURNAL ARTICLE
Zhonglin Li, Rui Gong, Huikuan Chu, Junchao Zeng, Can Chen, Sanping Xu, Lilin Hu, Wenkang Gao, Li Zhang, Hang Yuan, Zilu Cheng, Cheng Wang, Meng Du, Qingjing Zhu, Li Zhang, Lin Rong, Xiaoqing Hu, Ling Yang
BACKGROUND: Metabolic associated fatty liver disease (MAFLD) is a novel concept proposed in 2020, which is more practical for identifying patients with fatty liver disease with high risk of disease progression. Fatty liver is a driver for extrahepatic complications, particularly cardiovascular diseases (CVD). Although the risk of CVD in MAFLD could be predicted by carotid ultrasound test, a very early stage prediction method before the formation of pathological damage is still lacking...
March 22, 2024: Atherosclerosis
https://read.qxmd.com/read/38581328/feasibility-of-ultrasound-guided-percutaneous-axillary-artery-cannulation-for-veno-arterial-extracorporeal-membrane-oxygenation-and-its-effect-on-the-recovery-of-spontaneous-heartbeat-in-patients-with-ecpr
#24
JOURNAL ARTICLE
Minlong Liu, Guihe Zhang, Yizhan Cao, Chao Li, Bo Shi, Maomao Zhao, Gang Lin, Xin Chang, Xiangming Ma, Qing Li, Jie Zhao, Dong Chen, Long Zhang
OBJECTIVE: The measurement of the right and left axillary arteries and aortic arch and their vessels by multi-row spiral CT angiography provides the basis for clinical catheter selection and depth for axillary artery placement. This study reported the clinical experience of 7 patients who successfully underwent ultrasound-guided percutaneous axillary artery cannulation for veno-arterial extracorporeal membrane oxygenation (VA-ECMO). METHODS: Patients who had CT angiography of the thoracic aorta at our institution between January 2020 and March 2022 were assessed for eligibility and included...
April 5, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38581319/carotid-ultrasound-combined-with-plasma-atherosclerosis-index-aip-in-the-severe-analysis-of-coronary-heart-disease-treated-with-atorvastatin
#25
JOURNAL ARTICLE
Bin Zhang, Di Yang, Min Xu, Jian-Jun Wu, Zhen-Hua Ling
BACKGROUND: Atherosclerotic coronary heart disease (CHD) stands as a paramount cardiovascular concern and the primary cause of mortality. To underscore the significance of our study, it is crucial to highlight the existing gaps in current diagnostic methods and prognostic assessments of CHD. By addressing these gaps, our research aims to contribute valuable insights and advancements in the understanding and management of this prevalent cardiovascular condition. OBJECTIVE: The primary objective of this study is to investigate the correlation between carotid ultrasound, the Atherogenic Index of Plasma (AIP), and the severity of CHD...
April 5, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38579303/prognostic-impact-of-carotid-plaque-imaging-using-total-plaque-area-added-to-score2-in-middle-aged-subjects-the-arteris-cardiovascular-outcome-arco-cohort-study
#26
JOURNAL ARTICLE
Michel Romanens, Ansgar Adams, Michel Wenger, Walter Warmuth, Isabella Sudano
AIMS: Many cardiovascular events occur in seemingly healthy individuals.We set out to assess the predictive value of atherosclerosis imaging in combination with cardiovascular risk calculators in subjects aged 40-65 years. METHODS: We compared PROCAM (PROspective CArdiovascular Münster study), SCORE (Systematic COronary Risk Evaluation) and SCORE2 with carotid ultrasound (total plaque area, TPA) in subjects without cardiovascular disease. In this prospective cohort study, follow-up was obtained by phone or mail from patients; or from clinical records, if needed...
January 25, 2024: Swiss Medical Weekly
https://read.qxmd.com/read/38572043/assessment-of-cardiovascular-risk-factors-in-women-having-female-pattern-hair-loss
#27
JOURNAL ARTICLE
Damini Verma, Vibhu Mendiratta, Taru Garg, Smita Tripathi, Shaili Tomer
BACKGROUND: Many studies have associated male androgenetic alopecia with the risk of cardiovascular disorders but very few studies have addressed this association in women with FPHL. MATERIALS AND METHODS: This was a cross-sectional hospital-based study in which a total of 50 women (18-45 years) were recruited. The objective was to measure carotid intima-media thickness (CIMT) by doppler ultrasound, Body mass index (BMI), waist circumference, lipid profile, fasting blood sugar (FBS), insulin, testosterone, Sex hormone binding globulin (SHBG), hs-CRP, ESR and fibrinogen, in pre-menopausal women having FPHL and to correlate these parameters with severity of FPHL...
2024: Indian Journal of Dermatology
https://read.qxmd.com/read/38569375/long-term-cognitive-and-neurovascular-changes-after-carotid-endarterectomy
#28
JOURNAL ARTICLE
Kristiina Relander, Marja Hietanen, Petra Ijäs, Krista Nuotio, Pirkka Vikatmaa, Suvi M Koskinen, Marianne Ala-Kauhaluoma, Teemu I Paajanen, Jussi Virkkala, Perttu J Lindsberg, Lauri Soinne
BACKGROUND: Carotid endarterectomy (CEA) has been associated with both cognitive decline and improvement, but the underlying neurovascular mechanisms are unclear. The aim of this study was to investigate the relationship between neurovascular indices and cognitive changes after CEA. METHODS: We studied 55 patients with severe (≥70%) symptomatic or asymptomatic carotid stenosis before and six months after CEA. A wide array of neuropsychological tests was arranged in eight cognitive domains and cognitive functions specific to hemisphere ipsilateral to operation...
March 28, 2024: Journal of the Neurological Sciences
https://read.qxmd.com/read/38564354/branched-convolutional-neural-networks-for-receiver-channel-recovery-in-high-frame-rate-sparse-array-ultrasound-imaging
#29
JOURNAL ARTICLE
William M K Pitman, Di Xiao, Billy Y S Yiu, Adrian J Y Chee, Alfred C H Yu
For high-frame-rate ultrasound imaging, it remains challenging to implement on compact systems as a sparse imaging configuration with limited array channels. One key issue is that the resulting image quality is known to be mediocre not only because unfocused plane-wave excitations are used, but also because grating lobes would emerge in sparse array configurations. In this paper, we present the design and use of a new channel recovery framework to infer full-array plane-wave channel datasets for periodically sparse arrays that operate with as few as one-quarter of the full-array aperture...
April 2, 2024: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://read.qxmd.com/read/38564106/focused-ultrasound-on-the-substantia-nigra-enables-safe-neurotensin-polyplex-nanoparticle-mediated-gene-delivery-to-dopaminergic-neurons-intranasally-and-by-blood-circulation
#30
JOURNAL ARTICLE
Juan U Mascotte-Cruz, Arturo Vera, Lorenzo Leija, Francisco E Lopez-Salas, Michael Gradzielski, Joachim Koetz, Bismark Gatica-García, C P Rodríguez-Oviedo, Irais E Valenzuela-Arzeta, Lourdes Escobedo, David Reyes-Corona, M E Gutierrez-Castillo, Minerva Maldonado-Berny, Armando J Espadas-Alvarez, Carlos E Orozco-Barrios, Daniel Martinez-Fong
Neurotensin-polyplex nanoparticles provide efficient gene transfection of nigral dopaminergic neurons when intracerebrally injected in preclinical trials of Parkinson's disease because they do not cross the blood-brain barrier (BBB). Therefore, this study aimed to open BBB with focused ultrasound (FUS) on the substantia nigra to attain systemic and intranasal transfections and evaluate its detrimental effect in rats. Systemically injected Evans Blue showed that a two-pulse FUS opened the nigral BBB. Accordingly, 35 μL of neurotensin-polyplex nanoparticles encompassing the green fluorescent protein plasmid (79...
April 2, 2024: Discov Nano
https://read.qxmd.com/read/38562360/interdisciplinary-successful-revascularization-of-traumatic-occlusion-of-the-right-common-carotid-artery
#31
Boris Ilchev, Vasil Chervenkov, Nikolay Valchev, Vladimir Nakov, Tsvetan Minchev, Georgi Vassilev, Tsvetomir Tsvetanov, Lili Laleva, Milko Milev, Toma Spiriev
Blunt carotid artery injury (BCI) poses a rare yet severe threat following vascular trauma, often leading to significant morbidity and mortality. We present a case of a 33-year-old male who suffered complete thrombotic occlusion of the right common carotid artery (CCA) following a workplace accident. Clinical evaluation revealed profound neurological deficits, prompting multidisciplinary surgical intervention guided by the Denver criteria (Grade I - disruption inside the vessel that results in a narrowing of the lumen by less than 25%; Grade II - dissection or intramural hematoma causing greater than 25% stenosis; Grade III - comprises pseudoaneurysm formation; Grade IV - causes total vessel occlusion; Grade V - describes vessel transection with extravasation)...
March 2024: Curēus
https://read.qxmd.com/read/38561655/mobility-related-brain-regions-linking-carotid-intima-media-thickness-to-specific-gait-performances-in-old-age
#32
JOURNAL ARTICLE
Xin Zhang, Heyang Lu, Min Fan, Weizhong Tian, Mei Cui, Yanfeng Jiang, Chen Suo, Tiejun Zhang, Kelin Xu, Yingzhe Wang, Xingdong Chen
BACKGROUND: Gait disturbance is common in older adults with vascular diseases. However, how carotid atherosclerosis affects gait remains poorly understood. The objectives were to investigate the associations between carotid intima-media thickness and specific gait performances and explore the potential role of brain structure in mediating these associations. METHODS: A cross-sectional analysis of data from the Taizhou Imaging Study was conducted, including 707 individuals who underwent both gait and carotid ultrasound examinations...
April 1, 2024: BMC Geriatrics
https://read.qxmd.com/read/38552474/subclinical-vascular-composites-predict-clinical-cardiovascular-disease-stroke-and-dementia-the-multi-ethnic-study-of-atherosclerosis-mesa
#33
JOURNAL ARTICLE
Timothy M Hughes, Jordan Tanley, Haiying Chen, Christopher L Schaich, Joseph Yeboah, Mark A Espeland, Joao A C Lima, Bharath Ambale-Venkatesh, Erin D Michos, Jingzhong Ding, Kathleen Hayden, Ramon Casanova, Suzanne Craft, Stephen R Rapp, José A Luchsinger, Annette L Fitzpatrick, Susan R Heckbert, Wendy S Post, Gregory L Burke
BACKGROUND AND AIMS: Subclinical cardiovascular disease (CVD) measures may reflect biological pathways that contribute to increased risk for coronary heart disease (CHD) events, stroke, and dementia beyond conventional risk scores. METHODS: The Multi-Ethnic Study of Atherosclerosis (MESA) followed 6814 participants (45-84 years of age) from baseline in 2000-2002 to 2018 over 6 clinical examinations and annual follow-up interviews. MESA baseline subclinical CVD procedures included: seated and supineblood pressure, coronary calcium scan, radial artery tonometry, and carotid ultrasound...
March 15, 2024: Atherosclerosis
https://read.qxmd.com/read/38549767/a-siamese-resnext-network-for-predicting-carotid-intimal-thickness-of-patients-with-t2dm-from-fundus-images
#34
JOURNAL ARTICLE
AJuan Gong, Wanjin Fu, Heng Li, Na Guo, Tianrong Pan
OBJECTIVE: To develop and validate an artificial intelligence diagnostic model based on fundus images for predicting Carotid Intima-Media Thickness (CIMT) in individuals with Type 2 Diabetes Mellitus (T2DM). METHODS: In total, 1236 patients with T2DM who had both retinal fundus images and CIMT ultrasound records within a single hospital stay were enrolled. Data were divided into normal and thickened groups and sent to eight deep learning models: convolutional neural networks of the eight models were all based on ResNet or ResNeXt...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38545778/intraoperative-completion-studies-and-their-associations-with-carotid-endarterectomy-outcomes
#35
JOURNAL ARTICLE
Christoph Knappich, Bianca Bohmann, Felix Kirchhoff, Vanessa Lohe, Shamsun Naher, Michael Kallmayer, Hans-Henning Eckstein, Andreas Kuehnl
OBJECTIVE: This study aimed at assessing outcomes after carotid endarterectomy (CEA) in dependence of center policy with respect to imaging intraoperative completion study (ICSi) usage. SUMMARY BACKGROUND DATA: Although randomized controlled studies are missing, a beneficial effect was shown for ICSi techniques (i.e., angiography and intraoperative duplex ultrasound) after CEA. METHODS: This secondary data analysis is based on the German statutory quality assurance database...
March 28, 2024: Annals of Surgery
https://read.qxmd.com/read/38545713/-not-available
#36
JOURNAL ARTICLE
Sarra Laabidi, Mouna Medhioub, Amal Khsiba, Asma Bach Ali, Asma Ben Mohamed, Lamine Hamzaoui
INTRODUCTION: The impact of direct antiviral drugs (DAAs) on extrahepatic manifestations in chronic hepatitis C (CHC) has been poorly studied. AIM: To assess the prevalence of subclinical atherosclerosis in patients with CHC and the impact of DAAs on atherosclerotic lesions. Methods A 5-year prospective evaluative study, including patients followed for CHC at hepato-gastroenterology department. The subclinical atherosclerosis was assessed by ultrasound measurement of carotid intima-media thickness (IMTc) and the highest IMTc measurements from the left and right side defined the IMTc maximum (IMTc max)...
March 5, 2024: La Tunisie Médicale
https://read.qxmd.com/read/38541966/an-evaluation-of-plasma-tnf-vegf-a-and-il-6-determination-as-a-risk-marker-of-atherosclerotic-vascular-damage-in-early-onset-cad-patients
#37
JOURNAL ARTICLE
Marta Bialecka, Michał Rac, Violetta Dziedziejko, Krzysztof Safranow, Dariusz Chlubek, Monika Ewa Rać
Background : The pathogenesis of atherosclerosis is multifactorial and diverse. Pro-inflammatory cytokines are involved in these processes. It is suggested that inflammation may represent a novel and modifiable risk factor for cardiovascular disease. Therefore, this study aimed to gain insight into the relationship between plasma concentrations of TNF, VEGF, IL-6, and radiological parameters of atherosclerosis progression in patients with early-onset coronary artery disease (CAD). Methods: Seventy clinically stable patients were included in the study group...
March 18, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541182/takayasu-s-arteritis-a-special-case-report-and-review-of-the-literature
#38
REVIEW
Paloma Moisii, Irina Jari, Alexandru Gratian Naum, Doina Butcovan, Grigore Tinica
Background : Takayasu's arteritis is a rare type of vasculitis with severe complications like stroke, ischemic heart disease, pulmonary hypertension, secondary hypertension, and aneurysms. Diagnosis is achieved using clinical and angiographic criteria. Treatment is medical and surgical, but unfortunately, the outcome is limited. Case presentation : A 34-year-old Caucasian woman had an ischemic stroke (2009). She was diagnosed with Takayasu's arteritis and received treatment with methotrexate, prednisolone, and antiplatelet agents, with a mild improvement in clinical state...
March 9, 2024: Medicina
https://read.qxmd.com/read/38541164/unlocking-the-dietary-puzzle-how-macronutrient-intake-shapes-the-relationship-between-visfatin-and-atherosclerosis-in-type-2-diabetes
#39
JOURNAL ARTICLE
Kati Kärberg, Alastair Forbes, Margus Lember
Background and Objectives . Optimal nutrition for type 2 diabetes (T2DM) aims to improve glycemic control by promoting weight loss and reducing adipose tissue, consequently improving cardiovascular health. Dietary alterations can influence adipose tissue metabolism and potentially impact adipocytokines like visfatin, thereby affecting atherosclerosis development. This study aimed to investigate dietary habits and adherence to recommendations among individuals with T2DM and to examine how dietary adherence influences the association between visfatin and subclinical atherosclerosis...
March 6, 2024: Medicina
https://read.qxmd.com/read/38541101/what-is-the-added-value-of-carotid-ceus-in-the-characterization-of-atherosclerotic-plaque
#40
REVIEW
Andrejs Lioznovs, Maija Radzina, Laura Saule, Peteris Einars Grinbergs, Aigars Lacis
Background and Objectives : Unstable atherosclerotic plaque in the arteries is one of the main risk factors for cerebral ischemia. Duplex ultrasound is a frequently used diagnostic method, but it has some limitations for microvascularization and neovascularization evaluation. The aim of this review was to evaluate the role of the new multiparametric US method-contrast-enhanced ultrasound (CEUS)-in atherosclerotic plaque instability verification. Materials and Methods : Original studies, reviews, and meta-analyses were included in this article...
February 23, 2024: Medicina
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