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https://www.readbyqxmd.com/read/29778925/deep-learning-strategy-for-accurate-carotid-intima-media-thickness-measurement-an-ultrasound-study-on-japanese-diabetic-cohort
#1
Mainak Biswas, Venkatanareshbabu Kuppili, Tadashi Araki, Damodar Reddy Edla, Elisa Cuadrado Godia, Luca Saba, Harman S Suri, Tomaž Omerzu, John R Laird, Narendra N Khanna, Andrew Nicolaides, Jasjit S Suri
MOTIVATION: The carotid intima-media thickness (cIMT) is an important biomarker for cardiovascular diseases and stroke monitoring. This study presents an intelligence-based, novel, robust, and clinically-strong strategy that uses a combination of deep-learning (DL) and machine-learning (ML) paradigms. METHODOLOGY: A two-stage DL-based system (a class of AtheroEdge™ systems) was proposed for cIMT measurements. Stage I consisted of a convolution layer-based encoder for feature extraction and a fully convolutional network-based decoder for image segmentation...
May 12, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29773245/validation-of-an-open-source-tool-for-measuring-carotid-lumen-diameter-and-intima-media-thickness
#2
Hugo Luis Manterola, Lucas Lo Vercio, Alejandro Díaz, Mariana Del Fresno, Ignacio Larrabide
In low- and middle-income regions, a relatively large number of deaths occur from cardiovascular disease or stroke. Carotid intima-media thickness (cIMT) and carotid lumen diameter (cLD) are strong indicators of cardiovascular event risk and stenosis severity, respectively. The interactive open-source software described here, Cimtool, is based on active contours for measuring these indicators in clinical practice and thus helping in preventive diagnosis and treatment. Cimtool was validated using carotid phantoms and real images obtained using ultrasound...
May 14, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29766804/cyclophilin-a-a-predictive-biomarker-of-carotid-stenosis-in-cerebral-ischemic-stroke
#3
Chen-Shu Chang, Shih-Li Su, Chen-Ling Kuo, Ching-Shan Huang, Wan-Min Tseng, Song-Shei Lin, Chin-San Liu
BACKGROUND: Cyclophilin A plays a pathogenic role in the development and progression of atherosclerosis, which can be assessed by measuring carotid intima-media thickness. The primary aim of this study was to examine the interaction between plasma Cyclophilin A level and carotid intima-media thickness in patients with acute ischemic stroke. METHOD: Plasma concentration of Cyclophilin A was measured on admission in 66 consecutive patients who had been hospitalized for acute cerebral stroke and in 52 case-control subjects without a history of acute stroke...
May 16, 2018: Current Neurovascular Research
https://www.readbyqxmd.com/read/29764509/ultrasound-guided-fine-needle-aspiration-of-retropharyngeal-lymph-nodes-after-radiotherapy-for-nasopharyngeal-carcinoma-a-novel-technique-for-accurate-diagnosis
#4
Long-Jun He, Chuanbo Xie, Yin Li, Lin-Na Luo, Ke Pan, Xiao-Yan Gao, Li-Zhi Liu, Jian-Ming Gao, Guang-Yu Luo, Hong-Bo Shan, Ming-Yuan Chen, Chong Zhao, Wei-Jun Fan, Ping Yang, Guo-Liang Xu, Jian-Jun Li
BACKGROUND: Enlarged retropharyngeal lymph nodes (RLNs) are very common in patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy. The most suitable treatment option for enlarged RLNs depends on the pathological results. However, RLN sampling is difficult and imminent in the clinic setting. We recently developed a novel minimally invasive technique termed endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for sampling RLN tissues sufficient for pathological or cytological diagnosis...
May 9, 2018: Cancer communications
https://www.readbyqxmd.com/read/29762755/obstructive-sleep-apnea-during-rem-sleep-is-associated-with-early-signs-of-atherosclerosis-in-women
#5
Mirjam Ljunggren, Eva Lindberg, Karl A Franklin, Patrik Öhagen, Marita Larsson, Jenny Theorell-Haglöw, Tord Naessén
Study Objectives: While obstructive sleep apnea (OSA) is associated with overall cardiovascular disease and mortality, the association with atherosclerotic cardiovascular disease is less clear, especially in women. Recently, it has been suggested that OSA during REM sleep, associated with long apneas and deep desaturations, could have severe cardio-metabolic consequences. The aim of this study was to investigate whether OSA during REM sleep is associated with early signs of atherosclerosis in a population-based sample of women...
May 14, 2018: Sleep
https://www.readbyqxmd.com/read/29761548/variation-of-carotid-intima-media-thickness-with-body-mass-index-in-healthy-adults-of-black-african-descent
#6
Adesola Abiodun Asaleye, Kolawole Thomas Braimoh, Olalekan Ibukun Oyinloye, Christianah Mopelola Asaleye, Adeleye Dorcas Omisore
OBJECTIVES: Studies have shown that common carotid intima media thickness (CIMT) measured by B-mode sonography increases with body mass index (BMI) among subjects with cardiovascular diseases in different populations. However, association of body fat and subclinical atherosclerosis in the absence of these cardiovascular diseases is understudied. We aimed to evaluate the correlation between BMI and CIMT in a healthy adult population of black African ancestry. METHODS: This is a cross-sectional prospective study in 300 consecutive apparently healthy subjects aged 18 to 70 years without history of hypertension, dyslipidemia, diabetes mellitus, and renal disease...
May 15, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29760679/hematocrit-values-predict-carotid-intimal-media-thickness-in-obese-patients-with-non-alcoholic-fatty-liver-disease-a-cross-sectional-study
#7
Giovanni Tarantino, Luigi Barrea, Domenico Capone, Vincenzo Citro, Teresa Mosca, Silvia Savastano
Background: Literature data suggest with some criticism that full-fledged cardiovascular (CV) events (acute or chronic) are likely predicted by blood components, which are reported to be associated with the presence/severity of non-alcoholic fatty liver disease (NAFLD). This study was aimed at determining which marker(s) derived from blood count, such as white blood cells, neutrophils, neutrophil/lymphocyte ratio, platelet count, hemoglobin, mean corpuscular volume, hematocrit values were associated with ear or subclinical atherosclerosis, in obese patients of various classes suffering from NAFLD...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29754908/an-operational-definition-of-shats-systemic-hemodynamic-atherosclerotic-syndrome-role-of-arterial-stiffness-and-blood-pressure-variability-in-elderly-hypertensive-subjects
#8
Angelo Scuteri, Valentina Rovella, Danilo Alunni Fegatelli, Manfredi Tesauro, Marco Gabriele, Nicola Di Daniele
BACKGROUND: CV risk exponentially increases as the number of damaged organs increases The Systemic Hemodynamic Atherosclerotic Syndrome (SHATS) represents a novel conceptualization of the CV continuum focusing on simultaneous multi-organ alteration. This is the first study operationally defining SHATS and aimed at identifying its determinants. METHODS: Left Ventricular Hypertrophy (echocardiography), Common Carotid Artery plaque and increased thickness (ultrasound), and Chronic Kidney Disease (estimated Glomerular Filtration Rate) indexed selective target organ damage...
July 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29751282/sleep-duration-and-subclinical-atherosclerosis-the-aragon-workers-health-study
#9
Elena Blasco-Colmenares, Belén Moreno-Franco, Montserrat León Latre, Eusebio Mur-Vispe, Miguel Pocovi, Estíbaliz Jarauta, Fernando Civeira, Martín Laclaustra, José A Casasnovas, Eliseo Guallar
BACKGROUND AND AIMS: Few studies have evaluated the association of sleep duration with subclinical atherosclerosis, and with heterogeneous findings. We evaluated the association of sleep duration with the presence of coronary, carotid, and femoral subclinical atherosclerosis in healthy middle-age men with low prevalence of clinical comorbidities. METHODS: We performed a cross-sectional analysis of 1968 men, 40-60 years of age, participating in the Aragon Workers' Health Study (AWHS)...
May 3, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29747013/relationship-between-high-sodium-and-low-pufa-intake-and-carotid-atherosclerosis-in-elderly-women
#10
Elisa Mazza, Yvelise Ferro, Theodora Lamprinoudi, Carmine Gazzaruso, Patrizia Doldo, Arturo Pujia, Tiziana Montalcini
Several biologically active molecules including nutrients can affect the vascular endothelium which becomes dysfunctional and, as a consequence, predisposes to atherosclerosis. However, the impact of the intake of sodium and polyunsaturated fatty acids on carotid atherosclerosis in a population of elderly women has scarcely been studied. Our aim was to investigate the association between carotid intima-media thickness and atherosclerotic plaque and nutrient intake in asymptomatic elderly women. Carotid atherosclerosis was determined by duplex ultrasound in 108 elderly women...
May 7, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29744621/carotid-artery-intima-media-thickness-measurement-in-children-with-normal-and-increased-body-mass-index-a-comparison-of-three-techniques
#11
Ramy El Jalbout, Guy Cloutier, Marie-Hélène Roy Cardinal, Mélanie Henderson, Chantale Lapierre, Gilles Soulez, Josée Dubois
BACKGROUND: Common carotid artery intima-media thickness is a marker of subclinical atherosclerosis. In children, increased intima-media thickness is associated with obesity and the risk of cardiovascular events in adulthood. OBJECTIVE: To compare intima-media thickness measurements using B-mode ultrasound, radiofrequency (RF) echo tracking, and RF speckle probability distribution in children with normal and increased body mass index (BMI). MATERIALS AND METHODS: We prospectively measured intima-media thickness in 120 children randomly selected from two groups of a longitudinal cohort: normal BMI and increased BMI, defined by BMI ≥85th percentile for age and gender...
May 9, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29744017/spontaneous-recanalization-after-carotid-artery-dissection-the-case-for-an-ultrasound-only-monitoring-strategy
#12
Sarah Lumsden, Gabor Rosta, Jean Bismuth, Alan B Lumsden, Zsolt Garami
Dissection of the internal carotid artery (ICA) accounts for 5% to 25% of ischemic strokes in young adults. We report a case of spontaneous recanalization of a traumatic ICA dissection in which carotid duplex (CDU) and transcranial color-coded duplex ultrasound (TCCD) were used. A 47-year-old male presented with intermittent episodes of headache, blurry vision, anisocoria, and loss of taste sensation following a whiplash injury while body surfing. Magnetic resonance angiogram (MRA) of the neck revealed absent flow in the cavernous ICA and a clot at the skull base...
October 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29742951/carotid-flow-as-a-surrogate-for-cardiac-output-measurement-in-hemodynamically-stable-participants
#13
Marian Sidor, Lalith Premachandra, Bishoy Hanna, Nanda Nair, Amit Misra
OBJECTIVE: Evaluation of common carotid artery (CCA) blood flow can provide valuable information regarding the hemodynamic status of a patient. Utilizing ultrasound, we aimed to evaluate the correlation between cardiac output and different hemodynamic parameters in the CCA, namely systolic carotid flow (SCF), corrected flow time (CFT), and total carotid flow (TCF). METHODS: We studied a pilot sample of 20 healthy volunteers. Hemodynamic parameters were collected in the right CCA and the heart at rest (baseline), 1-leg compression, 2-leg compression, and passive leg raise...
January 1, 2018: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29739796/prevalence-of-carotid-plaque-in-a-63-to-65-year-old-norwegian-cohort-from-the-general-population-the-ace-akershus-cardiac-examination-1950-study
#14
Håkon Ihle-Hansen, Thea Vigen, Hege Ihle-Hansen, Ole Morten Rønning, Trygve Berge, Bente Thommessen, Magnus Nakrem Lyngbakken, Eivind Bjørkan Orstad, Steve Enger, Ståle Nygård, Helge Røsjø, Arnljot Tveit
BACKGROUND: New data on extracranial carotid atherosclerosis are needed, as improved ultrasound techniques may detect more atherosclerosis, the definition of plaque has changed over the years, and better cardiovascular risk control in the population may have changed patterns of carotid arterial wall disease and actual prevalence of established cardiovascular disease. We investigated the prevalence of atherosclerotic carotid plaques and carotid intima-media thickness (cIMT) and their relation to cardiovascular risk factors in a middle-aged cohort from the general population...
May 8, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29735317/risk-marker-variability-in-subclinical-carotid-plaques-based-on-ultrasound-is-influenced-by-cardiac-phase-echogenicity-and-size
#15
Emma Nyman, Per Lindqvist, Ulf Näslund, Christer Grönlund
Identification of risk markers based on quantitative ultrasound texture analysis of carotid plaques has the ability to define vulnerable components that correlate with increased cardiovascular risk. However, data describing factors with the potential to influence the measurement variability of risk markers are limited. The aim of this study was to evaluate the influence of electrocardiogram-guided image selection, plaque echogenicity and area on carotid plaque risk markers and their variability in asymptomatic carotid plaques...
May 4, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29735315/accuracy-and-precision-of-a-plane-wave-vector-flow-imaging-method-in-the-healthy-carotid-artery
#16
Jonas Jensen, Carlos Armando Villagómez Hoyos, Marie Sand Traberg, Jacob Bjerring Olesen, Borislav Gueorguiev Tomov, Ramin Moshavegh, Simon Holbek, Matthias Bo Stuart, Caroline Ewertsen, Kristoffer Lindskov Hansen, Carsten Thomsen, Michael Bachmann Nielsen, Jørgen Arendt Jensen
The objective of the study described here was to investigate the accuracy and precision of a plane wave 2-D vector flow imaging (VFI) method in laminar and complex blood flow conditions in the healthy carotid artery. The approach was to study (i) the accuracy for complex flow by comparing the velocity field from a computational fluid dynamics (CFD) simulation to VFI estimates obtained from the scan of an anthropomorphic flow phantom and from an in vivo scan; (ii) the accuracy for laminar unidirectional flow in vivo by comparing peak systolic velocities from VFI with magnetic resonance angiography (MRA); (iii) the precision of VFI estimation in vivo at several evaluation points in the vessels...
May 4, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29733280/motion-tolerant-unfocused-imaging-of-physiological-waveforms-for-blood-pressure-waveform-estimation-using-ultrasound
#17
Joohyun Seo, Sabino J Pietrangelo, Charles G Sodini, Hae-Seung Lee
This paper details unfocused imaging using single-element ultrasound transducers for motion tolerant arterial blood pressure (ABP) waveform estimation. The ABP waveform is estimated based on pulse wave velocity and arterial pulsation through Doppler and M-mode ultrasound. This paper discusses approaches to mitigate the effect of increased clutter due to unfocused imaging on blood flow and diameter waveform estimation. An intensity reduction model (IRM) estimator is described to track the change of diameter, which outperforms a complex cross-correlation model (C3M) estimator in low contrast environments...
May 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/29733275/noninvasive-estimation-of-pressure-changes-using-2-d-vector-velocity-ultrasound-an-experimental-study-with-in-vivo-examples
#18
Jacob Bjerring Olesen, Carlos Armando Villagomez-Hoyos, Niclas Dechau Moller, Caroline Ewertsen, Kristoffer Lindskov Hansen, Michael Bachmann Nielsen, Bo Bech, Lars Lonn, Marie Sand Traberg, Jorgen Arendt Jensen
A noninvasive method for estimating intravascular pressure changes using 2-D vector velocity is presented. The method was first validated on computational fluid dynamic (CFD) data and with catheter measurements on phantoms. Hereafter, the method was tested in vivo at the carotid bifurcation and at the aortic valve of two healthy volunteers. Ultrasound measurements were performed using the experimental scanner SARUS, in combination with an 8 MHz linear array transducer for experimental scans and a carotid scan, whereas a 3...
May 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/29729072/glycated-hemoglobin-correlates-with-arterial-stiffness-and-endothelial-dysfunction-in-patients-with-resistant-hypertension-and-uncontrolled-diabetes-mellitus
#19
Beatriz Moreno, Ana Paula de Faria, Alessandra Mileni Versuti Ritter, Lara Buonalumi Tacito Yugar, Silvia Elaine Ferreira-Melo, Rivadavio Amorim, Rodrigo Modolo, André Fattori, Juan Carlos Yugar-Toledo, Antonio Coca, Heitor Moreno
This study aimed to evaluate the effects of glycated hemoglobin (HbA1c ) on flow-mediated dilation, intima-media thickness, pulse wave velocity, and left ventricular mass index in patients with resistant hypertension (RHTN) comparing RHTN-controlled diabetes mellitus and RHTN-uncontrolled type 2 diabetes mellitus. Two groups were formed: HbA1c <7.0% (RHTN-controlled diabetes mellitus: n = 98) and HbA1c ≥7.0% (RHTN-uncontrolled diabetes mellitus: n = 122). Intima-media thickness and flow-mediated dilation were measured by high-resolution ultrasound, left ventricular mass index by echocardiography, and arterial stiffness by carotid-femoral pulse wave velocity...
May 5, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29728117/diabetic-retinopathy-is-associated-with-the-presence-and-burden-of-subclinical-carotid-atherosclerosis-in-type-1-diabetes
#20
Marc Carbonell, Esmeralda Castelblanco, Xavier Valldeperas, Àngels Betriu, Alícia Traveset, Minerva Granado-Casas, Marta Hernández, Federico Vázquez, Mariona Martín, Esther Rubinat, Albert Lecube, Josep Franch-Nadal, Elvira Fernández, Manel Puig-Domingo, Angelo Avogaro, Núria Alonso, Dídac Mauricio
BACKGROUND: Cardiovascular (CV) disease due to atherosclerosis is a major cause of morbidity and mortality in adult patients with diabetes, either type 1 or type 2 diabetes. The aim of the study was to assess the association of the frequency and the burden of subclinical carotid atherosclerotic disease in patients with type 1 diabetes according to the presence and severity of diabetic retinopathy (DR). METHODS: A cross-sectional study was conducted in 340 patients with type 1 diabetes (41...
May 4, 2018: Cardiovascular Diabetology
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