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https://www.readbyqxmd.com/read/27906147/biogenic-synthesis-of-silver-nanoparticles-from-cassia-fistula-linn-in-vitro-assessment-of-their-antioxidant-antimicrobial-and-cytotoxic-activities
#1
Yugal Kishore Mohanta, Sujogya Kumar Panda, Kunal Biswas, Abiral Tamang, Jaya Bandyopadhyay, Debashis De, Dambarudhar Mohanta, Akshaya Kumar Bastia
The present study reports on biogenic-synthesised silver nanoparticles (AgNPs) derived by treating Ag ions with an extract of Cassia fistula leaf, a popular Indian medicinal plant found in natural habitation. The progress of biogenic synthesis was monitored time to time using a ultraviolet-visible spectroscopy. The effect of phytochemicals present in C. fistula including flavonoids, tannins, phenolic compounds and alkaloids on the homogeneous growth of AgNPs was investigated by Fourier-transform infrared spectroscopy...
December 2016: IET Nanobiotechnology
https://www.readbyqxmd.com/read/27877231/chemomodulatory-potential-of-bartogenic-acid-against-dmba-croton-oil-induced-two-step-skin-carcinogenesis-in-mice
#2
Chandragouda R Patil, Bhavin M Sonara, Umesh B Mahajan, Kalpesh R Patil, Dipak D Patil, Ramchandra B Jadhav, Sameer N Goyal, Shreesh Ojha
Barringtonia racemosa fruits are believed to be useful in cancer treatment in Ayurveda, the Indian system of medicine. In present study, bartogenic acid (BA), a triterpenoid constituent of Barringtonia fruits was evaluated for its cytotoxicity property using the human skin carcinoma cell line (SCC-13) and human peripheral blood mononuclear cells (PBMC). The chemopreventive efficacy of BA was evaluated against the DMBA/Croton oil-induced skin carcinogenesis in mice.BA was orally administered at the doses of 1, 2 or 4 mg/kg/day or applied topically every day for 12 weeks following DMBA application...
2016: Journal of Cancer
https://www.readbyqxmd.com/read/27855495/pharmacological-importance-characterization-and-applications-of-gold-and-silver-nanoparticles-synthesized-by-panax-ginseng-fresh-leaves
#3
Priyanka Singh, Hina Singh, Sungeun Ahn, Verónica Castro-Aceituno, Zuly Jiménez, Shakina Yesmin Simu, Yeon Ju Kim, Deok Chun Yang
Previously, we showed the rapid and eco-friendly synthesis of gold and silver nanoparticles within 3 and 45 min by fresh leaves extract of herbal medicinal plant Panax ginseng. In addition, we characterized the nanoparticles in terms of shape, size, morphology and stability by FE-TEM, EDX, elemental mapping, SEAD, XRD and particles size analysis. In addition of this, we showed their antimicrobial, anti-coagulant, and biofilm inhibition activity of nanoparticles. Continuing our previous study, here we highlight the further characterization and biomedical applications of P...
November 18, 2016: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/27843296/evaluating-the-cytotoxic-effects-of-the-water-extracts-of-four-anticancer-herbs-against-human-malignant-melanoma-cells
#4
Binbing Ling, Deborah Michel, Meena Kishore Sakharkar, Jian Yang
Malignant melanoma (MM) is the most dangerous type of skin cancer, killing more than 1,100 people each year in Canada. Prognosis for late stage and recurrent MM is extremely poor due to insensitivity to chemotherapy drugs, and thus many patients seek complementary and alternative medicines. In this study, we examined four commonly used anticancer herbs in traditional Chinese medicine, Hedyotis diffusa, Scutellaria barbata, Lobelia chinensis, and Solanum nigrum, for their in vitro antitumor effects toward human MM cell line A-375...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27831631/stem-cells-differentiation-and-probing-their-therapeutic-applications-in-hematological-disorders-a-critical-review
#5
F Ali, S Taresh, M Al-Nuzaily, P L Mok, A Ismail, S Ahmad
Numerous lines of evidence support that bone marrow is a rich source of stem cells that can be used for research purposes and to treat some complex blood diseases and cancers. Stem cells are a potential source for regenerative medicine and tissue replacement after injury or disease, and mother cells that possess the capacity to become any type of cell in the body. They are cells without specific structure and characterized by their ability to self-renew or multiply while maintaining the potential to develop into other types of cells...
October 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27766546/management-of-skin-cancer-in-the-high-risk-patient
#6
James W Behan, Adam Sutton, Ashley Wysong
Skin cancer is the most common of human cancers and outnumbers all other types of cancer combined in the USA by over threefold. The majority of non-melanoma skin cancers are easily treated with surgery or locally destructive techniques performed under local anesthesia in the cost-effective outpatient setting. However, there is a subset of "high-risk" cases that prove challenging in terms of morbidity, mortality, adjuvant treatment required, as well as overall cost to the health care system. In our opinion, the term "high risk" when applied to skin cancer can mean one of three things: a high-risk tumor with aggressive histologic and/or clinical features with an elevated risk for local recurrence or regional/distant metastasis, a high-risk patient with the ongoing development of multiple skin cancers, and a high-risk patient based on immunosuppression...
December 2016: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/27746884/erlotinib-induced-fatal-interstitial-lung-disease-in-a-patient-with-metastatic-non-small-cell-lung-cancer-case-report-and-review-of-literature
#7
Ankit Mangla, Nikki Agarwal, Chou Carmel, Thomas Lad
Erlotinib is one of the most widely used tyrosine kinase inhibitor targeting human epidermal growth factor receptor. Since its introduction, it has revolutionized the treatment of advanced non-small cell lung cancer. Skin rashes and diarrhea are the most often reported side effects of erlotinib however it is also associated with interstitial pneumonitis or interstitial lung disease, which often turns out to be fatal complication of using this medicine. Though reported scarcely in the western world, the association of interstitial lung disease with epidermal growth factor receptor has attracted a lot of attention in the recent times...
September 5, 2016: Rare Tumors
https://www.readbyqxmd.com/read/27743314/learning-needs-of-gynecologic-cancer-survivors
#8
Gulcihan Akkuzu, Gonul Kurt, Gulten Guvenc, Gulsah Kok, Sevgi Simsek, Safiye Dogrusoy, Ali Ayhan
To define the learning needs of patients with gynecological oncology. The study was performed as a descriptive study. A total of 92 patients were participated. Data were collected using Patient Learning Needs Scale (PLNS). The Pearson correlation test, independent sample t test, and analysis of one-way of variance (ANOVA) followed by Tukey's-B post hoc tests were used for statistical analyses by the SPSS 15.0 software package. The mean age of women's was 50.37 ± 12.20 years. The women's diagnoses were cervical (45...
October 15, 2016: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/27714915/classifying-skin-diseases-until-where-should-we-go
#9
Sélim Aractingi
New molecular mapping techniques appear to allow clinicians to design treatments in some cases of resisting cancers. Such sensitive analysis were already able to depict molecular pathways of several inflammatory skin diseases. An accompanying article by Garzorz-Stark et al. show how these tools can improve the classification of skin inflammatory diseases based on clinical and pathological features. At last, the final aim of these tools is to predict treatment response in a patient. The utility of "precision" or personalized medicine in cutaneous inflammatory diseases could join the furrow drawn in cancer...
October 7, 2016: Experimental Dermatology
https://www.readbyqxmd.com/read/27682402/chromatographic-fingerprint-bioactivity-relationships-of-the-antitumor-properties-of-bufo-bufo-gargarizans-skin-extracts
#10
Lulu Sun, Jing Zhang, Surong Zhao, Qiong Pan, Hongmin Zhang, Hao Liu, Zhitao Zhang
Statistical analyses of high-performance liquid chromatography (HPLC)-based chemical fingerprints of Bufo bufo gargarizans toad skin extracts were integrated with antitumor evaluations as a means to more effectively identify bioactive constituents. Specifically, chemical fingerprints of Bufo bufo gargarizans skin extract samples obtained from ten different regions in China were generated by HPLC, and then subjected to similarity analysis and principal component analysis (PCA). Concurrently, a MCF-7 breast cancer cell model was adopted to obtain the antitumor activity of different toad skin extracts...
2016: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/27649680/ginkgo-biloba-exocarp-extracts-inhibits-angiogenesis-and-its-effects-on-wnt-%C3%AE-catenin-vegf-signaling-pathway-in-lewis-lung-cancer
#11
Dongdong Han, Chengjie Cao, Ya Su, Jun Wang, Jian Sun, Huasheng Chen, Aihua Xu
ETHNOPHARMACOLOGICAL RELEVANCE: A fruit of Ginkgo biloba L. also known as Ginkgo biloba, can be used for the treatment of cancer in Chinese traditional medicine. The scientific name of succulent skin, which is the episperm of Ginkgo nuts, is exocarp. Experiment shows that Ginkgo biloba exocarp extracts (GBEE) has the effects of immune promotion, cancer inhibition and etc. AIM OF STUDY: Study on the activity of GBEE against Lewis lung cancer (LLC) angiogenesis and its partial molecular mechanism...
November 4, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27641607/phytochemical-profile-and-biological-activity-of-juglans-regia
#12
REVIEW
Nisha Panth, Keshav Raj Paudel, Rajendra Karki
Juglans regia Linn. (Juglandaceae), popularly known as English or Persian walnut, is a valuable medicinal plant with a potency to cure various diseases in traditional medicine. Since ancient time, different local ethnic groups have used various part of J. regia for a wide array of ailments including helminthiasis, diarrhea, sinusitis, stomach ache, arthritis, asthma, eczema, scrofula, skin disorders, diabetes mellitus, anorexia, thyroid dysfunction, cancer and infectious diseases. Biological activities of J...
September 2016: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27616033/kochia-scoparia-induces-apoptosis-of-oral-cancer-cells-in-vitro-and-in-heterotopic-tumors
#13
Hye-Yeon Han, Haeng-Eun Lee, Hyung Joon Kim, Seung-Hwa Jeong, Jung-Hoon Kim, Hyungwoo Kim, Mi Heon Ryu
ETHNOPHARMACOLOGICAL RELEVANCE: Kochia scoparia grows commonly in China, Japan, and Korea and its mature fruit has been used throughout the area in traditional medicine to treat diseases including skin problems and inflammatory and allergic disease. More importantly, Kochia scoparia has been prescribed to treat the malignant tumor of head and neck region and breast mass. Although it has been proposed as an anti-cancer agent for several cancers, its exact in vivo anti-cancer properties and the molecular mechanisms underlying its effects are poorly understood...
November 4, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27603115/cajanus-cajan-a-source-of-ppar%C3%AE-activators-leading-to-anti-inflammatory-and-cytotoxic-effects
#14
Roswitha Schuster, Wolfgang Holzer, Hannes Doerfler, Wolfram Weckwerth, Helmut Viernstein, Siriporn Okonogi, Monika Mueller
Cajanus cajan is an important legume crop in the human diet in many parts of the world. Due to its pharmacological properties, C. cajan is, moreover, used in traditional medicine for treating skin diseases, diabetes, inflammatory disorders and various other dysfunctions. In this study, we focused on the role of peroxisome proliferator-activated receptor gamma (PPARγ) as a potential therapeutic target of Cajanus cajan and its main compounds for the treatment of cancer, inflammation and inflammation-related disorders...
September 14, 2016: Food & Function
https://www.readbyqxmd.com/read/27588747/sun-exposure-tanning-beds-and-herbs-that-cure-an-examination-of-skin-cancer-on-pinterest
#15
Lu Tang, Sung-Eun Park
: Skin cancer is the most common cancer affecting the U.S. POPULATION: Pinterest.com, a virtual bookmarking social media site, has the potential to disseminate skin cancer-related information among young women, the group with the fastest increase in skin cancer diagnosis. This article presents a quantitative content analysis of pins about skin cancer on Pinterest guided by agenda-setting theory and the health belief model. Overall, sun exposure and tanning beds were most frequently discussed as the causes of skin cancer, and alternative therapies such as herbal medicine were discussed more than traditional biomedical treatment or prevention...
September 2, 2016: Health Communication
https://www.readbyqxmd.com/read/27566079/baicalin-scavenged-reactive-oxygen-species-and-protected-human-keratinocytes-against-uvb-induced-cytotoxicity
#16
Wen-Shin Chang, En-Yuan Lin, Shih-Wei Hsu, Pei-Shin Hu, Chin-Liang Chuang, Cheng-Hsi Liao, Chun-Kai Fu, Chung-Hao Su, Chi-Li Gong, Chieh-Lun Hsiao, DA-Tian Bau, Chia-Wen Tsai
Ultraviolet B (UVB), with a wavelength of 280-320 nm, represents one of the most important environmental factors for skin disorders, including sunburn, hyperpigmentation, solar keratosis, solar elastosis and skin cancer. Therefore, protection against excessive UVA-induced damage is useful for prevention of sunburn and other human diseases. Baicalin, a major component of traditional Chinese medicine Scutellaria baicalensis, has been reported to possess antioxidant and cytostatic capacities. In this study, we examined whether baicalin is also capable of protecting human keratinocytes from UVB irradiation...
September 2016: In Vivo
https://www.readbyqxmd.com/read/27539464/the-use-of-low-level-light-therapy-in-supportive-care-for-patients-with-breast-cancer-review-of-the-literature
#17
Jolien Robijns, Sandrine Censabella, Paul Bulens, Annelies Maes, Jeroen Mebis
Breast cancer is the most common cancer in women worldwide, with an incidence of 1.7 million in 2012. Breast cancer and its treatments can bring along serious side effects such as fatigue, skin toxicity, lymphedema, pain, nausea, etc. These can substantially affect the patients' quality of life. Therefore, supportive care for breast cancer patients is an essential mainstay in the treatment. Low-level light therapy (LLLT) also named photobiomodulation therapy (PBMT) has proven its efficiency in general medicine for already more than 40 years...
August 19, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27512322/yoga-protocol-for-treatment-of-breast-cancer-related-lymphedema
#18
S R Narahari, Madhur Guruprasad Aggithaya, Liselotte Thernoe, Kuthaje S Bose, Terence J Ryan
INTRODUCTION: Vaqas and Ryan (2003) advocated yoga and breathing exercises for lymphedema. Narahari et al. (2007) developed an integrative medicine protocol for lower-limb lymphedema using yoga. Studies have hypothesized that yoga plays a similar role as that of central manual lymph drainage of Foldi's technique. This study explains how we have used yoga and breathing as a self-care intervention for breast cancer-related lymphedema (BCRL). METHODS: The study outcome was to create a yoga protocol for BCRL...
July 2016: International Journal of Yoga
https://www.readbyqxmd.com/read/27509953/prevalent-signs-and-symptoms-in-patients-with-skin-cancer-and-nursing-diagnoses
#19
Isabel Neves Duarte Lisboa, Monica Suela de Azevedo Macena, Maria Isabel Fernandes da Conceicao Dias, Ana Beatriz de Almeida Medeiros, Cyndi Fernandes de Lima, Ana Luisa Brandao de Carvalho Lira
BACKGROUND: Skin cancer has a remarkable importance given the high incidence in the population. In Brazil, it is estimated that there were 98,420 new cases of nonmelanoma skin cancer among men and 83,710 new cases among women in 2014. OBJECTIVES: To verify signs and symptoms present in patients with skin neoplasms according to the literature and relate them to the nursing diagnoses of NANDA International. MATERIALS AND METHODS: Integrative literature review carried out from March to May 2015 in the databases: Cumulative Index to Nursing and Allied Health Literature, SCOPUS, National Library of Medicine and Nattional Institutes of Health, Latin American and Caribbean Sciences of Health and Web of Science...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27509951/skin-cancer-clinicopathological-study-of-204-patients-in-southern-governorates-of-yemen
#20
Amer Bin AlZou, Mazen Abood Bin Thabit, Khalid Abdulla AlSakkaf, Huda Omer Basaleem
BACKGROUND: Skin cancer is a group of heterogeneous malignancies, in general classified into nonmelanoma skin cancer (NMSC) and melanoma skin cancer (MSC). Incidences are high in many parts in the world with considerable geographical and racial variation. In the Yemen, there has been scarce information about skin cancer. The aim of this study was to evaluate the demographic characteristics and histological trend of skin cancer in Southern Governorates of Yemen. MATERIALS AND METHODS: This retrospective study covered 204 cases of skin cancer at the Modern Histopathology Laboratory and Aden Cancer Registry and Research Center, Faculty of Medicine and Health Sciences, University of Aden, for the period 20062013...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
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