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https://www.readbyqxmd.com/read/29762699/cultivable-bacteria-from-pectinatella-magnifica-and-the-surrounding-water-in-south-bohemia-indicate-potential-new-gammaproteobacterial-betaproteobacterial-and-firmicutes-taxa
#1
Hana Salmonová, Jirí Killer, Vera Bunešová, Martina Geigerová, Eva Vlková
Pectinatella magnifica is a freshwater bryozoan, which has become a subject of scientific interest because of its invasive expansion worldwide. To obtain a comprehensive overview of its influence on environments, information on associated bacteria is needed. In this study, cultivable bacteria associated with P. magnifica were investigated. In total, 253 isolates were selected for preliminary identification by MALDI-TOF mass spectrometry and clustered based on REP-PCR profiles. Among these, 169 strains were selected and identified using 16S rRNA gene comparative analyses...
May 14, 2018: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/29718820/characteristics-of-surgical-site-infection-following-colorectal-surgery-in-a-tertiary-center-extended-spectrum-%C3%AE-lactamase-producing-bacteria-culprits-in-disease
#2
Eliana Kalakouti, Constantinos Simillis, Gianluca Pellino, Nabeela Mughal, Oliver Warren, Sarah Mills, Emile Tan, Christos Kontovounisios, Paris P Tekkis
INTRODUCTION: Surgical site infection (SSI) is a well-known complication of colorectal surgery associated with increased morbidity and hospital stay. Antimicrobial prophylaxis can reduce the risk of SSI by as much as 75%. Extended-spectrum β-lactamase (ESBL)-producing pathogens make the successful use of such prophylaxis a challenge and are a real threat to patient care following colorectal surgery. OBJECTIVE: The aim of this study is to report the common characteristics of SSIs after colorectal surgery and to highlight the prevalence, risk factors, and clinical relevance of ESBL infections among these patients in a tertiary center...
December 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29718423/efflux-pump-inhibitor-cccp-to-rescue-colistin-susceptibility-in-mcr-1-plasmid-mediated-colistin-resistant-strains-and-gram-negative-bacteria
#3
Sophie A Baron, Jean-Marc Rolain
Objectives: Efflux in bacteria is a ubiquitous mechanism associated with resistance to antimicrobials agents. Efflux pump inhibitors (EPIs) have been developed to inhibit efflux mechanisms and could be a good alternative to reverse colistin resistance, but only CCCP has shown good activity. The aim of our study was to identify CCCP activity in a collection of 93 Gram-negative bacteria with known and unknown colistin resistance mechanisms including isolates with mcr-1 plasmid-mediated colistin resistance...
April 26, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29628289/novel-class-1-integron-in1390-harboring-bla-ges-5-in-a-morganella-morganii-strain-recovered-from-a-remote-community
#4
Quézia Moura, Louise Cerdeira, Miriam R Fernandes, Marco A Vianello, Nilton Lincopan
Antimicrobial resistance in Morganella morganii has been mainly acquired via plasmids and class 1 integrons. We hereby report acquisition of blaGES-5 by a M. morganii isolated in a remote community from the Amazon region. Genomic analysis revealed that blaGES-5 was harbored by a novel class 1 integron designated as In1390.
March 10, 2018: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/29616001/dissemination-of-kpc-2-encoding-incx6-plasmids-among-multiple-enterobacteriaceae-species-in-a-single-chinese-hospital
#5
Bing Li, Jiao Feng, Zhe Zhan, Zhe Yin, Qiyu Jiang, Ping Wei, Xingming Chen, Bo Gao, Jun Hou, Panyong Mao, Weili Wu, Weijun Chen, Yigang Tong, Jinglin Wang, Boan Li, Dongsheng Zhou
Forty-five KPC-producing Enterobacteriaceae strains were isolated from multiple departments in a Chinese public hospital from 2014 to 2015. Genome sequencing of four representative strains, namely Proteus mirabilis GN2, Serratia marcescens GN26, Morganella morganii GN28, and Klebsiella aerogenes E20, indicated the presence of bla KPC-2 -carrying IncX6 plasmids pGN2-KPC, pGN26-KPC, pGN28-KPC, and pE20-KPC in the four strains, respectively. These plasmids were genetically closely related to one another and to the only previously sequenced IncX6 plasmid, pKPC3_SZ...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29579836/early-bacterial-pneumonia-after-hepatic-transplantation-epidemiologic-profile
#6
J Prieto Amorin, M Lopez, K Rando, J Castelli, J Medina Presentado
BACKGROUND: Postoperative pulmonary complications are major cause of morbidity and mortality in patients receiving liver transplantation (LT), particularly bacterial pneumonia occurring within the first 100 days after transplantation. Our aim in this study was to determine the incidence, microorganisms involved, associated factors, and morbidity of bacterial pneumonia presenting in the first 100 days posttransplant. METHODS: We performed a cohort study in which patients receiving liver transplantation were included prospectively in our national database (Database of Infections in Transplantation of Solid Organs)...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29571839/activity-of-omadacycline-tested-against-enterobacteriaceae-causing-urinary-tract-infections-from-a-global-surveillance-program-2014
#7
M A Pfaller, P R Rhomberg, M D Huband, R K Flamm
Omadacycline is an aminomethylcycline with in vitro activity against many gram-negative pathogens. Omadacycline and comparators were tested against Enterobacteriaceae from urinary tract infections (UTIs) selected from a 2014 global surveillance program and compared to results of isolates from 2010 surveillance. The omadacycline MIC50/90 for Enterobacteriaceae collected during 2014 was 2/≥8 μg/mL (1/4 μg/mL minus Proteus, Providencia, and Morganella spp.). The MIC50/90 for E. coli was 1/2 μg/mL, similar to that in 2010 (MIC50/90 , 0...
February 24, 2018: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/29571292/genetic-contexts-related-to-the-diffusion-of-plasmid-mediated-ctx-m-55-extended-spectrum-beta-lactamase-isolated-from-enterobacteriaceae-in-china
#8
Xiaoxin Hu, Jianjun Gou, Xiaobing Guo, Zaiqiu Cao, Yuan Li, Hongjian Jiao, Xiaohong He, Yihui Ren, Fuyun Tian
BACKGROUND: CTX-M-55 extended-spectrum beta-lactamases are being rapidly disseminated and transmitted in clinical practices around the world. The genetic contexts of the transferable plasmid-mediated blaCTX-M-55 gene in Enterobacteriaceae were detected and characterized in this study. METHODS: Isolates were obtained from the First Affiliated Hospital of Zhengzhou University between September 2015 and March 2016. Based on polymerase chain reaction and BLAST analysis, resistance genes and genetic context of the blaCTX-M-55 gene were investigated...
March 23, 2018: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/29566147/species-specific-mutation-rates-for-ampc-derepression-in-enterobacterales-with-chromosomally-encoded-inducible-ampc-%C3%AE-lactamase
#9
Rebekka Kohlmann, Tobias Bähr, Sören G Gatermann
Background: AmpC β-lactamases are encoded on the chromosomes of certain Enterobacterales and lead to clinical resistance to various β-lactams in case of high-level expression. In WT bacteria with inducible AmpC, the expression is low, but selection of stably ampC-derepressed mutants may occur during β-lactam therapy. Thus, for Enterobacter spp., Citrobacter freundii complex, Serratia spp. and Morganella morganii that test susceptible in vitro to oxyimino-cephalosporins, the EUCAST expert rules recommend suppressing susceptibility testing results for these agents or noting that their use in monotherapy should be discouraged, owing to the risk of selecting resistance...
March 16, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29564881/first-report-of-genital-ulcer-due-to-morganella-morganii-infection
#10
Emanuele Cozzani, Giulia Ciccarese, Francesco Drago, Daniela Gerbaldo, Aurora Parodi
No abstract text is available yet for this article.
April 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29522506/chromotrace-computational-reconstruction-of-3d-chromosome-configurations-for-super-resolution-microscopy
#11
Carl Barton, Sandro Morganella, Øyvind Ødegård-Fougner, Stephanie Alexander, Jonas Ries, Tomas Fitzgerald, Jan Ellenberg, Ewan Birney
The 3D structure of chromatin plays a key role in genome function, including gene expression, DNA replication, chromosome segregation, and DNA repair. Furthermore the location of genomic loci within the nucleus, especially relative to each other and nuclear structures such as the nuclear envelope and nuclear bodies strongly correlates with aspects of function such as gene expression. Therefore, determining the 3D position of the 6 billion DNA base pairs in each of the 23 chromosomes inside the nucleus of a human cell is a central challenge of biology...
March 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29493728/microbial-flora-and-antibiotic-resistance-in-odontogenic-abscesses-in-upstate-new-york
#12
Ann W Plum, Anthony J Mortelliti, Ronald E Walsh
Abscesses in the head and neck frequently have odontogenic sources. As bacterial pathogens and antibiotic resistance patterns may change over time and based on location, we describe the current common bacteria found in odontogenic abscesses, the prevalence of antibiotic resistance, and differences in each between pediatric and adult patients in Upstate New York. This is a retrospective review of patients who underwent drainage of odontogenic abscesses (n = 131) from 2002 to 2012 at an academic institution. The medical records were reviewed for results of abscess cultures, comorbidities, and drainage procedures...
January 2018: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29475568/emergence-of-plasmid-mediated-colistin-resistance-mcr-1-among-enterobacteriaceae-strains-laboratory-detection-of-resistance-and-measures-to-control-its-dissemination
#13
D Lepelletier, R Bonnet, P Plésiat, M H Nicolas-Chanoine, A Berger-Carbonne, C Chidiac, B Grandbastien
The increasing use of colistin has contributed to the emergence of resistant bacteria and to an increase in the frequency of infections caused by naturally resistant Enterobacteriaceae strains such as Proteus, Providencia, Morganella, and Serratia. In August 2016, the French High Council for Public Health (French acronym HCSP) received a request from the Ministry of Health on the advice of the French National Public Health agency (Santé publique France) with regard to measures that should be taken to tackle the emergence of plasmid-mediated colistin resistance among Enterobacteriaceae strains...
February 20, 2018: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/29472795/effect-of-gut-bacterial-isolates-from-apis-mellifera-jemenitica-on-paenibacillus-larvae-infected-bee-larvae
#14
Ahmad Al-Ghamdi, Khalid Ali Khan, Mohammad Javed Ansari, Saad B Almasaudi, Saad Al-Kahtani
The probiotic effects of seven newly isolated gut bacteria, from the indegenous honey bees of Saudi Arabia were investigated. In vivo bioassays were used to investigate the effects of each gut bacterium namely, Fructobacillus fructosus (T1), Proteus mirabilis (T2), Bacillus licheniformis (T3), Lactobacillus kunkeei (T4), Bacillus subtilis (T5), Enterobacter kobei (T6), and Morganella morganii (T7) on mortality percentage of honey bee larvae infected with P. larvae spores along with negative control (normal diet) and positive control (normal diet spiked with P...
February 2018: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/29471688/plasmid-mediated-quinolone-resistance-determinants-in-enterobacteriaceae-from-urine-clinical-samples
#15
Orsolya Szabó, Dániel Gulyás, Nikolett Szabó, Katalin Kristóf, Béla Kocsis, Dóra Szabó
Plasmid-mediated quinolone resistance (PMQR) determinants including, qnrA, qnrB, qnrC, qnrD, qnrS, aac(6')-Ib-cr, oqxAB, and qepA, were investigated in 214 Enterobacteriaceae strains from urine clinical samples. Antimicrobial susceptibility testing for ciprofloxacin, ceftriaxone, and imipenem was performed by broth microdilution method. All strains were screened for PMQR genes by PCR. Virulence determinants, namely afa, pap, pil, sfa/foc, and kpsMT of eight Escherichia coli strains proven positive for at least one qnr gene, were investigated by PCR...
February 23, 2018: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/29435240/gut-microbiota-in-the-burying-beetle-nicrophorus-vespilloides-provide-colonization-resistance-against-larval-bacterial-pathogens
#16
Yin Wang, Daniel E Rozen
Carrion beetles, Nicrophorus vespilloides, are reared on decomposing carrion where larvae are exposed to high populations of carcass-derived bacteria. Larvae do not become colonized with these bacteria but instead are colonized with the gut microbiome of their parents, suggesting that bacteria in the beetle microbiome outcompete the carcass-derived species for larval colonization. Here, we test this hypothesis and quantify the fitness consequences of colonization with different bacterial symbionts. First, we show that beetles colonized by their endogenous microbiome produce heavier broods than those colonized with carcass-bacteria...
February 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29288840/morganella-as-a-cause-of-ophthalmia-neonatorum
#17
Michael F Ward, Daniel J Olson, Michael Taggart, Sara F Grace
A 2 day-old-girl with a complicated birth history, including prolonged rupture of membranes and Caesarian section delivery, presented with a purulent bacterial conjunctivitis of the left eye despite standard prophylaxis. Bacterial cultures yielded 1+ Morganella morganii, a facultative anaerobe and a rare cause of ocular pathology. The patient was treated with topical tobramycin four times daily for 7 days, resulting in resolution of her conjunctivitis.
February 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29223516/antimicrobial-activity-of-plazomicin-against-enterobacteriaceae-producing-carbapenemases-from-50-brazilian-medical-centers
#18
Andreza Francisco Martins, Larissa Bail, Carmen Antonia Sanches Ito, Keite da Silva Nogueira, Tanise Vendruscolo Dalmolin, Amanda Silva Martins, Jaime Luis Lopes Rocha, Alisa W Serio, Felipe Francisco Tuon
Plazomicin is a next-generation aminoglycoside with activity against Enterobacteriaceae, including carbapenemase-producing Enterobacteriaceae (CPE). The aim of this study was to evaluate the activity of plazomicin against CPE (Klebsiella spp., Escherichia coli, Serratia spp., Enterobacter spp., Citrobacter spp., Morganella spp., Proteus spp., Providencia spp.) from different Brazilian hospitals. A total of 4000 carbapenem-resistant Enterobacteriaceae isolates were collected from clinical samples in 50 Brazilian hospitals during 2013-2015...
March 2018: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/29183746/assessment-of-the-anti-snakebite-properties-of-extracts-of-aniba-fragrans-ducke-lauraceae-used-in-folk-medicine-as-complementary-treatment-in-cases-of-envenomation-by-bothrops-atrox
#19
Valéria Mourão de Moura, Noranathan da Costa Guimarães, Luana Travassos Batista, Luciana A Freitas-de-Sousa, Joanderson de Sousa Martins, Maria Carolina Scheffer de Souza, Patrícia D Oliveira de Almeida, Wuelton Marcelo Monteiro, Ricardo Bezerra de Oliveira, Maria Cristina Dos-Santos, Rosa Helena Veras Mourão
ETHNOPHARMACOLOGICAL RELEVANCE: Extracts of leaves and bark of Aniba fragrans are used as tea (decoction) to treat snakebites in communities in the Brazilian Amazon. The aqueous extract of the leaves of A. fragrans has been proven to be effective against Bothrops venom, but only when pre-incubated with the venom. This study sought to assess the potential of different types of extract of this species to inhibit the biological activities of Bothrops atrox venom (BaV) when used the same way as in folk medicine...
March 1, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29149019/incidence-and-consequences-of-near-drowning-related-pneumonia-a-descriptive-series-from-martinique-french-west-indies
#20
Laura Cerland, Bruno Mégarbane, Hatem Kallel, Yanick Brouste, Hossein Mehdaoui, Dabor Resiere
Drowning represents one major cause of accidental death. Near-drowning patients are exposed to aspiration that may result in pneumonia with life-threatening consequences. We designed this descriptive study to investigate the frequency, nature, and consequences of post-drowning pneumonia. One hundred and forty-four near-drowning patients (33 children and 111 adults) admitted during four years to the University Hospital of Martinique, French Indies, were included. Patients presented pre-hospital cardiac arrest (41%) and exhibited acute respiratory failure (54%), cardiovascular failure (27%), and lactic acidosis (75%) on admission...
November 17, 2017: International Journal of Environmental Research and Public Health
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