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Morganella

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https://www.readbyqxmd.com/read/28919283/clinical-manifestations-risk-factors-and-prognosis-of-patients-with-morganella-morganii-sepsis
#1
David Erlanger, Marc Victor Assous, Yonit Wiener-Well, Amos Moshe Yinnon, Eli Ben-Chetrit
BACKGROUND: There are few studies of Morganella bacteremia. We evaluated risk factors and outcome of patients with Morganella bacteremia. METHODS: Medical records of patients with Morganella bacteremia were reviewed (1997-2014). Control group patients with Escherichiacoli sepsis were matched by year of diagnosis and infection acquisition site. RESULTS: The study group included 136 adult patients. Mean age and gender of study and control groups were similar...
September 6, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28904067/whole-genome-sequencing-reveals-breast-cancers-with-mismatch-repair-deficiency
#2
Helen Davies, Sandro Morganella, Colin A Purdie, Se Jin Jang, Elin Borgen, Hege Russnes, Dominik Glodzik, Xueqing Zou, Alain Viari, Andrea L Richardson, Anne-Lise Børresen-Dale, Alastair Thompson, Jorunn E Eyfjord, Gu Kong, Michael R Stratton, Serena Nik-Zainal
Mismatch repair (MMR)-deficient cancers have been discovered to be highly responsive to immune therapies such as PD-1 checkpoint blockade, making their definition in patients, where they may be relatively rare, paramount for treatment decisions. In this study, we utilized patterns of mutagenesis known as mutational signatures, which are imprints of the mutagenic processes associated with MMR deficiency, to identify MMR-deficient breast tumors from a whole-genome sequencing dataset comprising a cohort of 640 patients...
September 13, 2017: Cancer Research
https://www.readbyqxmd.com/read/28877672/chronic-lower-extremity-wound-infection-due-to-kerstersia-gyiorum-in-a-patient-with-buerger-s-disease-a-case-report
#3
Irmak Baran, Arife Polat Düzgün, İpek Mumcuoğlu, Neriman Aksu
BACKGROUND: Kerstersia gyiorum is an extremely rare pathogen of human infection. It can cause chronic infection in patients with underlying conditions. It can easily be misdiagnosed if proper diagnostic methods are not used. CASE PRESENTATION: A 47-year-old male patient with a history of Buerger's Disease for 28 years presented to our hospital with an infected chronic wound on foot. The wound was debrided, and the specimen was sent to Microbiology laboratory. Gram staining of the specimen showed abundant polymorphonuclear leukocytes and gram-negative bacilli...
September 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28838340/isolation-identification-and-characterization-of-morganella-morganii-from-naja-naja-atra-in-beijing-china
#4
H-F Wang, L-Y Du, J Luo, H-X He
Morganella morganii is an important opportunistic human pathogen and belongs to the family of Enterobacteriaceae. Although it is widely distribution, it only be considered a rare cause of human infections. We report the isolate of M. morganii from Naja naja atra following infections of heart, lung and liver. Seven strains were confirmed using 16S rDNA amplified and sequences. Antimicrobial susceptibility testing of M. morganii isolates demonstrated ubiquitous resistance to ampicillin, amoxicillin/clavulanic acid, cefazolin, cephalothin, sulfamethoxazole/trimethoprim, sulfamethoxazole et al...
August 15, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28811229/necrotizing-fasciitis-following-venomous-snakebites-in-a-tertiary-hospital-of-southwest-taiwan
#5
Yao-Hung Tsai, Wei-Hsiu Hsu, Kuo-Chin Huang, Pei-An Yu, Chi-Lung Chen, Liang Tseng Kuo
BACKGROUND: Necrotizing fasciitis following venomous snakebites is uncommon. The purpose of this study was to describe the initial clinical features of necrotizing fasciitis after snakebites, and to identify the risk factors for patients with cellulitis who later developed necrotizing fasciitis. METHODS: Sixteen patients with surgically confirmed necrotizing fasciitis and 25 patients diagnosed with cellulitis following snakebites were retrospectively reviewed over a 6-year period...
August 12, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28805537/high-prevalence-of-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-in-wild-fish-from-the-mediterranean-sea-in-algeria
#6
Soumia Brahmi, Abdelaziz Touati, Catherine Dunyach-Remy, Albert Sotto, Alix Pantel, Jean-Philippe Lavigne
AIM: We investigated the prevalence of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae among wild fish from the coast of Bejaia (Algeria) in the Mediterranean Sea. RESULTS: From March 2012 to August 2013, gut and gill samples of wild fish were screened for the presence of ESBL-producing Enterobacteriaceae. Strains were characterized with regard to antibiotic resistance, β-lactamase content, plasmid-mediated quinolone resistance, aminoglycoside resistance genes, and clonality (repetitive sequence-based polymerase chain reaction profiles and multilocus sequence typing)...
August 14, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28761787/a-mutualism-without-honeydew-what-benefits-for-melissotarsus-emeryi-ants-and-armored-scale-insects-diaspididae
#7
Christian Peeters, Imre Foldi, Danièle Matile-Ferrero, Brian L Fisher
Mutualisms between ants and sap-sucking insects generally involve clear benefits for both partners: the ants provide protection in exchange for honeydew. However, a single ant genus associates with armoured scale insects (Diaspididae) that do not excrete honeydew. We studied three colonies of Melissotarsus emeryi ants from two localities in Mozambique. Vast numbers of the diaspidid Morganella conspicua occupied galleries dug by the ants under the bark of living trees. Unlike free-living M. conspicua and other diaspidids, M...
2017: PeerJ
https://www.readbyqxmd.com/read/28733908/assessment-of-cultivable-oral-bacterial-flora-from-important-venomous-snakes-of-india-and-their-antibiotic-susceptibilities
#8
Innus K Shaikh, Prashant P Dixit, Balasaheb S Pawade, Mugdha Potnis-Lele, Babasaheb P Kurhe
Snakebite is a common, frequently devastating, occupational, socio-economic hazard, and it has a great impact on the rural population of India. Snakebite is a major cause of the human morbidity and mortality since ancient times, as it not only affects the victim by systemic envenomation but also by wound infections originating from deadly pathogenic microorganisms from the oral cavity of the offending snake. The pathogens from the oral cavity of the snake tend to initiate an infection, resulting in gas gangrene, soft tissue necrosis, and permanent physical disabilities...
July 21, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28705499/development-of-silver-nanoparticles-loaded-chitosan-alginate-constructs-with-biomedical-potentialities
#9
Muhammad Bilal, Tahir Rasheed, Hafiz M N Iqbal, Chuanlong Li, Hongbo Hu, Xuehong Zhang
Herein, a facile biosynthesis of silver nanoparticles (AgNPs) and AgNPs-loaded chitosan-alginate constructs with biomedical potentialities is reported. The UV-vis spectroscopic profile confirmed the synthesis of AgNPs using methanolic leaves extract of Euphorbia helioscopia. The newly developed AgNPs were characterized using various analytical and imaging techniques including UV-vis and FT-IR spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), atomic force microscopy (AFM), and transmission electron microscopy (TEM)...
July 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28698604/honeybee-apis-mellifera-associated-bacterial-community-affected-by-american-foulbrood-detection-of-paenibacillus-larvae-via-microbiome-analysis
#10
Tomas Erban, Ondrej Ledvinka, Martin Kamler, Marta Nesvorna, Bronislava Hortova, Jan Tyl, Dalibor Titera, Martin Markovic, Jan Hubert
Honeybee (Apis mellifera L.) workers act as passive vectors of Paenibacillus larvae spores, which cause the quarantine disease American foulbrood (AFB). We assessed the relative proportions of P. larvae within the honeybee microbiome using metabarcoding analysis of the 16 S rRNA gene. The microbiome was analyzed in workers outside of the AFB zone (control - AFB0), in workers from asymptomatic colonies in an AFB apiary (AFB1), and in workers from colonies exhibiting clinical AFB symptoms (AFB2). The microbiome was processed for the entire community and for a cut-off microbiome comprising pathogenic/environmental bacteria following the removal of core bacterial sequences; varroosis levels were considered in the statistical analysis...
July 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28696146/heat-resistance-of-histidine-decarboxylase-from-gram-negative-histamine-producing-bacteria-in-seafood
#11
K Bjornsdottir-Butler, F A Bencsath, S McCarthy, R A Benner
Precooking of tuna is a potential critical control point (CCP) in the commercial manufacturing of canned tuna. To assess the efficacy of precooking as a CCP, an understanding of the thermal properties of histamine-producing bacteria (HPB) and their histidine decarboxylase (HDC) enzymes is required. The thermal properties of many HPB have been determined, but the thermal resistances of the HDC enzymes are unknown. The purpose of this study was to determine the D- and z-values of selected HDC enzymes to evaluate the CCP of precooking during the canning process and provide scientific data to support U...
July 11, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28665245/prophylactic-use-of-intraoperative-vancomycin-powder-and-postoperative-infection-an-analysis-of-microbiological-patterns-in-1200-consecutive-surgical-cases
#12
Owoicho Adogwa, Aladine A Elsamadicy, Amanda Sergesketter, Victoria D Vuong, Ankit I Mehta, Raul A Vasquez, Joseph Cheng, Carlos A Bagley, Isaac O Karikari
OBJECTIVE Wound infections following spinal surgery for deformity place a high toll on patients, providers, and the health care system. The prophylactic application of intraoperative vancomycin powder has been shown to lower the infection risk after thoracolumbar decompression and fusion for deformity correction. The purpose of this study was to assess the microbiological patterns of postoperative surgical site infections (SSIs) after prophylactic use of vancomycin powder in adult patients undergoing spinal deformity surgery...
September 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28663705/investigation-of-gut-microbial-communities-associated-with-indigenous-honey-bee-apis-mellifera-jemenitica-from-two-different-eco-regions-of-saudi-arabia
#13
Khalid Ali Khan, Mohammad Javed Ansari, Ahmad Al-Ghamdi, Adgaba Nuru, Steve Harakeh, Javaid Iqbal
The microbial communities associated with the alimentary tract of honey bees are very important as they help with food digestion, provide essential nutrients, protect the host from pathogens, detoxify harmful molecules, and increase host immunity. In this study, the structural diversity of the gut microbial communities of native honey bees, Apis mellifera jemenitica from two different geographical regions (Riyadh and Al-Baha) of Saudi Arabia was analyzed by culture-dependent methods and 16S ribosomal RNA (rRNA) gene sequencing...
July 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28659135/bilateral-morganella-morganii-keratitis-in-a-patient-with-facial-topical-corticosteroid-induced-rosacea-like-dermatitis-a-case-report
#14
Bei Zhang, Fei Pan, Kejian Zhu
BACKGROUND: Bilateral keratitis rarely occurs in individuals without predisposing factors. Here we describe the clinical course of a patient who developed a bilateral keratitis caused by Morganella. morganii which might be associated with long term using of topical corticosteroids-containing preparations on the face. CASE PRESENTATION: A 52-year-old female patient presented with marked bilateral corneal infiltration and hypopyon without any usual predisposing factors for bilateral infectious keratitis...
June 28, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28658333/bacterial-genus-is-a-risk-factor-for-major-amputation-in-patients-with-diabetic-foot
#15
Natália Anício Cardoso, Lígia DE Loiola Cisneiros, Carla Jorge Machado, Juliana Merlin Cenedezi, Ricardo Jayme Procópio, Túlio Pinho Navarro
Objective: to evaluate whether bacterial genus is a risk factor for major amputation in patients with diabetic foot and infected ulcer. Methods: we conducted a case-control, observational study of 189 patients with infected ulcers in diabetic feet admitted to the Vascular Surgery Service of the Risoleta Tolentino Neves Hospital, from January 2007 to December 2012. The bacteriological evaluation was performed in deep tissue cultures from the lesions and amputation was considered major when performed above the foot'smiddle tarsus...
March 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28619802/draft-genome-sequences-of-extended-spectrum-beta-lactamase-producing-morganella-morganii-strains-aa1-and-av1-isolated-from-a-freshwater-lake-and-eicchorniacrassipes-roots
#16
Pushpa Lata, Subramaniam S Govindarajan, Feng Qi, Jian-Liang Li, Santosh K Maurya, Malaya K Sahoo
Two strains of Morganella morganii, AA1 and AV1, were isolated from freshwater and Eicchornia crassipes roots, respectively. Here, we report their draft genome sequences, which are ~3.6 Mb and have 51% G+C content. The predicted coding sequences (3,259 for strain AA1 and 3,345 for strain AV1) encode beta-lactamases, transpeptidases, and penicillin-binding proteins.
June 15, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28600898/investigation-of-acid-phosphatase-variants-for-the-synthesis-of-phosphate-monoesters
#17
Gábor Tasnádi, Michaela Zechner, Mélanie Hall, Kai Baldenius, Klaus Ditrich, Kurt Faber
The major drawback of using phosphatases for transphosphorylation reactions lies in product depletion caused by the natural hydrolytic activity of the enzymes. Variants of PhoC-Mm from Morganella morganii and NSAP-Eb from Escherichia blattae were studied for their ability to maintain a high product level in the transphosphorylation of various primary alcohols. A single amino acid exchange delivered phosphatase variant PhoC-Mm G92D, which was able to catalyze the phosphorylation of primary alcohols without any major hydrolysis of the formed phosphate esters...
June 10, 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/28600633/igm-mediated-autoimmune-responses-to-oxidative-specific-epitopes-but-not-nitrosylated-adducts-are-significantly-decreased-in-pregnancy-association-with-bacterial-translocation-perinatal-and-lifetime-major-depression-and-the-tryptophan-catabolite-trycat-pathway
#18
Chutima Roomruangwong, Buranee Kanchanatawan, Sunee Sirivichayakul, George Anderson, André F Carvalho, Sebastien Duleu, Michel Geffard, Michael Maes
Immunoglubulin (Ig)M responses directed to oxidative specific epitopes (OSEs) and nitric oxide (NO)-adducts are significantly associated with major depression and physio-somatic symptoms. End of term serum IgM responses to OSEs and NO-adducts were assayed in pregnant women with (n = 24) and without prenatal depression (n = 25) as well as in 24 non-pregnant women. Associations of IgM/IgA responses to Gram-negative gut commensal bacteria (leaky gut index) and IgA/IgM responses to tryptophan catabolites (TRYCATs) were analyzed...
June 9, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28586429/hafnia-an-enterobacterial-genus-naturally-resistant-to-colistin-revealed-by-three-susceptibility-testing-methods
#19
Aurélie Jayol, Marion Saly, Patrice Nordmann, Armelle Ménard, Laurent Poirel, Véronique Dubois
Objectives: To determine the susceptibility to colistin of Hafnia alvei and Hafnia paralvei, and to compare methods for colistin resistance detection in the Hafnia genus. Methods: A collection of 25 Hafnia isolates was studied. Species were identified by using 16S rRNA gene sequencing with subsequent phylogeny analysis. Susceptibility to colistin was determined using the broth microdilution (BMD) reference method, the Phoenix automated system, the Rapid Polymyxin NP test, the Etest system and the disc diffusion method...
September 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28572256/mutational-signatures-in-breast-cancer-the-problem-at-the-dna-level
#20
EDITORIAL
Serena Nik-Zainal, Sandro Morganella
A breast cancer genome is a record of the historic mutagenic activity that has occurred throughout the development of the tumor. Indeed, every mutation may be informative. Although driver mutations were the main focus of cancer research for a long time, passenger mutational signatures, the imprints of DNA damage and DNA repair processes that have been operative during tumorigenesis, are also biologically illuminating. This review is a chronicle of how the concept of mutational signatures arose and brings the reader up-to-date on this field, particularly in breast cancer...
June 1, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
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