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https://www.readbyqxmd.com/read/29783223/-rational-nutrition-as-a-prerequisite-for-eliminating-the-risk-of-overweight-public-opinion-and-practice
#1
Natalia O Ryngach, Marina B Scherbinina, Tatiana M Shevchenko, Victoria M Gladun, Volodymyr I Sarychev
OBJECTIVE: Introduction: The awareness of the working-age population regarding the principles of a healthy lifestyle and risk factors of diseases is analyzed. Aim: To identify and characterize the level of awareness of the working-age population regarding the essence of a healthy lifestyle and risk factors (with a focus on irrational nutrition and its consequences). PATIENTS AND METHODS: Materials and methods: In the sociological study (2017), on request of Dnipropetrovsk regional state administration, methods of deep (N20) and personalized formal interviews (N2000) were used according to a specially developed methodology of qualitative and quantitative research stages and data collection tools...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29782484/implications-for-human-odor-sensing-revealed-from-the-statistics-of-odorant-receptor-interactions
#2
Ji Hyun Bak, Seogjoo J Jang, Changbong Hyeon
Binding of odorants to olfactory receptors (ORs) elicits downstream chemical and neural signals, which are further processed to odor perception in the brain. Recently, Mainland and colleagues have measured more than 500 pairs of odorant-OR interaction by a high-throughput screening assay method, opening a new avenue to understanding the principles of human odor coding. Here, using a recently developed minimal model for OR activation kinetics, we characterize the statistics of OR activation by odorants in terms of three empirical parameters: the half-maximum effective concentration EC50, the efficacy, and the basal activity...
May 21, 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29782284/-magnetic-resonance-imaging-in-patients-with-implantable-devices-for-treatment-of-disturbed-heart-rhythm-review-of-the-current-situation
#3
A A Sviridova
The question of the possibility of MRI scanning in patients with cardiac implantable electronic devices (CIED) appeared simultaneously with the introduction of MRI in clinical practice. A lot of in-vitro, in-vivo and clinical researches were performed to estimate wat going on with CIED in strong magnetic field and is it possible to perform some unified protocol of safe MRI-scanning for these patients. Recommendations were provided, but not for the wide practice. MRI remained strongly contraindicated for CIED patient...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29782214/physiologic-changes-in-a-small-animal-model-for-neonatal-minimally-invasive-surgery
#4
Steffi Mayer, Nicole Peukert, Richard Gnatzy, Jan-Hendrik Gosemann, Martin Lacher, Anne Suttkus
BACKGROUND: Minimally invasive surgery (MIS) has gained increasing importance in neonatal surgery but the effects on neonatal physiology remain unclear. We aimed to characterize the impact of capnoperitoneum on physiologic parameters in a small animal model for neonatal MIS. MATERIAL AND METHODS: Twenty-four 10-day-old Sprague Dawley rats underwent inhalative anesthesia (1% isoflurane in 100% O2 250 mL/minutes) and were allowed to breathe spontaneously. CO2 was insufflated into the abdominal cavity for 1 hour via a 24G cannula...
May 21, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29781976/posterior-scleral-contraction-to-treat-recurrent-or-persistent-macular-detachment-after-previous-vitrectomy-in-highly-myopic-eyes
#5
Linyan Zheng, Anpeng Pan, Shuangqian Zhu, Yue Wu, Liang Dong, Anquan Xue
PURPOSE: To determine the efficacy of posterior scleral contraction (PSC) to treat recurrent or persistent macular detachment after previous vitrectomy in highly myopic eyes. METHODS: We reviewed the medical records of patients with high myopia and recurrent or persistent macular detachment after previous vitrectomy treated with PSC at our hospital between April 2013 and March 2017. Fourteen eyes (14 patients; mean age, 58.93 ± 11.08 years) were included. Sclera cross-linked with genipin was used for PSC...
May 16, 2018: Retina
https://www.readbyqxmd.com/read/29781963/comorbidities-and-mobility-in-lower-limb-prosthesis-users
#6
Shane R Wurdeman, Phillip M Stevens, James H Campbell
OBJECTIVE: To determine the impact of comorbidities on mobility in patients with lower limb prostheses. DESIGN: Cohort database chart review examining mobility in lower limb prosthesis users grouped according to comorbidities. Regression models were used to determine significant predictor comorbidities for mobility. General linear univariate models were implemented to investigate differences in mobility among cohorts (n=596). RESULTS: Patient age and history of stroke, peripheral vascular disease, and anxiety/panic disorders were predictors of decreased mobility...
May 17, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29781841/carbohydrates-and-diet-patterns-in-nonalcoholic-fatty-liver-disease-in-children-and-adolescents
#7
Ahlia Sekkarie, Jean A Welsh, Miriam B Vos
PURPOSE OF REVIEW: The primary treatment for nonalcoholic fatty liver disease (NAFLD) in children is lifestyle change, including a healthier diet. However, there are no agreed upon expert recommendations for a specific diet in the prevention or treatment of NAFLD. In this study, we review studies published between 2015 and 2017 contributing to further understanding of the role of diet in the development and progression of NAFLD, particularly those addressing sugars and dietary patterns...
May 16, 2018: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29781701/intervention-for-bilingual-speech-sound-disorders-a-case-study-of-an-isixhosa-english-speaking-child
#8
Kate Rossouw, Michelle Pascoe
 Bilingualism is common in South Africa, with many children acquiring isiXhosa as a home language and learning English from a young age in nursery or crèche. IsiXhosa is a local language, part of the Bantu language family, widely spoken in the country. Aims: To describe changes in a bilingual child's speech following intervention based on a theoretically motivated and tailored intervention plan. Methods and procedures: This study describes a female isiXhosa-English bilingual child, named Gcobisa (pseudonym) (chronological age 4 years and 2 months) with a speech sound disorder...
March 19, 2018: South African Journal of Communication Disorders. die Suid-Afrikaanse Tydskrif Vir Kommunikasieafwykings
https://www.readbyqxmd.com/read/29781608/characterization-of-the-il-electrode-interfacial-relaxation-processes-under-potential-polarization-for-ionic-liquid-amperometric-gas-sensor-method-development
#9
Lu Lin, Peng Zhao, Andrew J Mason, Xiangqun Zeng
Electrochemical amperometric sensors require a constant or varying potential at the working electrode that drives redox reactions of the analyte for detection. The interfacial redox reaction(s) can result in the formation of new chemical products that could change the initial condition of the electrode/electrolyte interface. If the products are not inert and/or cannot be removed from the system or if the initial condition of the electrode/electrolyte interface cannot be restored, the sensor signal baseline would consequently drift which is problematic for the continuous and real-time sensors...
May 21, 2018: ACS Sensors
https://www.readbyqxmd.com/read/29781463/hepatic-arterial-infusion-pump-complications-and-nursing-management-regarding-use-in-patients-with-colorectal-cancer
#10
Deborah Italiano
BACKGROUND: The hepatic arterial infusion (HAI) pump is a treatment-delivery method based on the principle of targeting the tumor site directly and can be used alone or in combination with systemic chemotherapy. OBJECTIVES: The intent of this article is to serve as a resource for oncology nurses to safely identify and manage HAI pump complications. These complications include seroma, flipped HAI pump, infection, changes in pressure and temperature, challenging access, dry pump, high residual volume, chemical hepatitis, risk of ulcer, and radiologic imaging considerations...
June 1, 2018: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29781462/multiple-myeloma-detecting-genetic-changes-through-bone-marrow-biopsy-and-the-influence-on-care
#11
Donna Catamero
Knowledge of genetic mutations and how these affect patient outcomes is rapidly expanding in the care of individuals diagnosed with multiple myeloma (MM). Genetic analysis of bone marrow biopsies now provides information about diagnosis,response to treatment, and prognosis. Oncology nurses need to understand the science and meaning of bone marrow biopsy reports, including the implications of genetic alterations and minimal residual disease. This will allow them to provide care, support, and education related to MM and its treatment to patients and their families...
June 1, 2018: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29781232/predictors-of-outcomes-in-managing-breast-abscesses-a-large-retrospective-single-center-analysis
#12
Miriam David, Priyanka Handa, Maria Castaldi
We have retrospectively examined a wide range of clinical characteristics, sonographic features, microbiology, and antibiotic regimens in patients with breast abscesses to seek predictive features related to outcome. Because consensus for optimal treatment of breast abscesses has moved toward minimally invasive management using single or repeated needle aspiration (ASP) coupled with adjuvant antibiotics, we assessed whether any factors correlate with the need for repeat procedures by analyzing the number of ASPs and/or surgical incision and drainage (I&D) per abscess...
May 20, 2018: Breast Journal
https://www.readbyqxmd.com/read/29781093/hippocampal-place-cell-encoding-of-sloping-terrain
#13
Blake S Porter, Robert Schmidt, David K Bilkey
Effective navigation relies on knowledge of one's environment. A challenge to effective navigation is accounting for the time and energy costs of routes. Irregular terrain in ecological environments poses a difficult navigational problem as organisms ought to avoid effortful slopes to minimize travel costs. Route planning and navigation have previously been shown to involve hippocampal place cells and their ability to encode and store information about an organism's environment. However, little is known about how place cells may encode the slope of space and associated energy costs as experiments are traditionally carried out in flat, horizontal environments...
May 21, 2018: Hippocampus
https://www.readbyqxmd.com/read/29781009/electrically-controlled-drug-release-using-ph-sensitive-polymer-films
#14
S Ephraim Neumann, Christian F Chamberlayne, Richard N Zare
Drug delivery systems (DDS) that allow spatially and temporally controlled release of drugs are of particular interest in the field of drug delivery. These systems create opportunities for individually tailored doses of drugs to be administered as well as reduce side effects by localizing the initial drug dose to the organ of interest. We present an electroresponsive DDS in the form of a bioresorbable nanocomposite film which operates at low voltages (<-2 V). The method is based on electrochemically generating local pH changes at an electrode surface to induce dissolution of a pH-sensitive polymer, which is used as the carrier material...
May 21, 2018: Nanoscale
https://www.readbyqxmd.com/read/29780544/the-enhancement-and-suppression-of-immersion-mode-heterogeneous-ice-nucleation-by-solutes
#15
Thomas F Whale, Mark A Holden, Theodore W Wilson, Daniel O'Sullivan, Benjamin J Murray
Heterogeneous nucleation of ice from aqueous solutions is an important yet poorly understood process in multiple fields, not least the atmospheric sciences where it impacts the formation and properties of clouds. In the atmosphere ice-nucleating particles are usually, if not always, mixed with soluble material. However, the impact of this soluble material on ice nucleation is poorly understood. In the atmospheric community the current paradigm for freezing under mixed phase cloud conditions is that dilute solutions will not influence heterogeneous freezing...
May 7, 2018: Chemical Science
https://www.readbyqxmd.com/read/29779472/effect-of-body-weight-on-metabolic-hormones-and-fatty-acid-metabolism-in-follicular-fluid-of-women-undergoing-in-vitro-fertilization-a-pilot-study
#16
Laurice Bou Nemer, Haolin Shi, Bruce Richard Carr, Ruth Ann Word, Orhan Bukulmez
INTRODUCTION: Obesity is an epidemic affecting more than one-third of adults in the United States. Obese women experience decreased fertility, explained in part by oocyte quality. Since follicular fluid (FF) provides an important microenvironment for oocyte growth, we sought to evaluate the effect of increased body weight on FF levels of 11 metabolic hormones and fatty acid metabolism. METHODS: The FF was collected from 25 women (10 normal weight, 10 overweight, and 5 obese) with diminished ovarian reserve undergoing in vitro fertilization (IVF) following a minimal stimulation protocol...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29779154/the-effect-of-meteorological-conditions-and-air-pollution-on-the-occurrence-of-type-a-and-b-acute-aortic-dissections
#17
Nan Xie, Liqun Zou, Lei Ye
To explore the association of weather conditions and air pollutants with incidence risk of acute aortic dissection (AAD), we included patients who consecutively admitted to the emergency units of our hospital for AAD between Dec. 1, 2013, and Apr. 30, 2017. Their medical records were reviewed. The meteorological data (daily precipitation, minimal and maximal temperatures, mean atmospheric pressure, relative humidity) and air pollutants values [air daily index (AQI), aerodynamic diameter of 2.5 mm or less (PM2...
May 19, 2018: International Journal of Biometeorology
https://www.readbyqxmd.com/read/29779119/a-chemosensitizer-drug-disulfiram-prevents-doxorubicin-induced-cardiac-dysfunction-and-oxidative-stress-in-rats
#18
Varsha K Sonawane, Umesh B Mahajan, Sachin D Shinde, Subhajit Chatterjee, Sandip S Chaudhari, Harshada A Bhangale, Shreesh Ojha, Sameer N Goyal, Chanakya N Kundu, Chandragouda R Patil
In the present study, the preventive effects of orally administered disulfiram (DS) against the doxorubicin (DOX)-induced cardiotoxicity were investigated in rats. DS was orally administered for 7 days at doses of 2, 10, and 50 mg/kg/day. DOX (30 mg/kg) was intraperitoneally administered on the 5th day of the initiation of DS treatment. Within 48 h of injection, DOX treatment significantly altered ECG, elevated the ST height, and increased the QT and QRS intervals. It reduced the cardiac levels of injury markers like creatine kinase isoenzyme-MB and lactate dehydrogenase...
May 10, 2018: Cardiovascular Toxicology
https://www.readbyqxmd.com/read/29778457/treatment-of-chronic-obstructive-pulmonary-disease-in-the-primary-care-setting-how-can-we-achieve-more-for-our-patients
#19
Barbara Yawn, Barry Make
Chronic obstructive pulmonary disease (COPD) is a debilitating and progressive disease that is both under-diagnosed and under-treated, affecting up to 1 in 10 older adults. Common symptoms, including dyspnea, productive cough, chest tightness, and fatigue, can reduce quality of life, ability to participate in all types of activities, and overall health status in patients. Minimizing the impact of symptoms on patients' quality of life should be a key goal for physicians and modest changes in current practice could make improvements in patients' lives...
May 17, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29778258/new-treatments-have-changed-the-game-hepatitis-c-treatment-in-primary-care
#20
REVIEW
Shelley N Facente, Katie Burk, Kelly Eagen, Elise S Mara, Aaron A Smith, Colleen S Lynch
In the pre-direct-acting antiviral era, hepatitis C virus (HCV) treatments were complex and largely managed by hepatologists, gastroenterologists, and infectious disease physicians. As direct-acting antivirals have driven up demand for treatment, the relative scarcity of these specialists has created a bottleneck effect, resulting in only a fraction of HCV-infected individuals offered treatment. The San Francisco Health Network is a safety net system of care. Its intervention was designed to be sustainable and scalable; with minimal time commitments for training providers, primary care-based HCV treatment increased 3-fold in a period of just over 3 years...
June 2018: Infectious Disease Clinics of North America
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