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https://www.readbyqxmd.com/read/29667830/dynamics-of-contact-line-pinning-and-depinning-of-droplets-evaporating-on-micro-ribs
#1
Ali Mazloomi Moqaddam, Dominique Derome, Jan Carmeliet
The contact line dynamics of evaporating droplets deposited on a set of parallel micro-ribs is analyzed with the use of a recently developed entropic lattice Boltzmann model for two-phase flow. Upon deposition, part of the droplet penetrates into the space between ribs due to capillary action, while the remaining liquid of the droplet remains pinned on top of the micro-ribs. In a first stage, evaporation continues until the droplet undergoes a series of pinning-depinning events, showing alternatively constant contact radius and constant contact angle modes...
April 18, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29667632/-the-peculiar-biochemical-properties-of-the-support-structures-in-the-human-tissues
#2
S G Kuzin, S G Sukhanov, Ya V Kazakov, A V Pyatlin
This article is focused on the methodological aspects of the evaluation of the elastic and mechanical strength characteristics of the tissues that form the flexible fibrous and osseous human skeleton. The samples of dura mater and spongy bone (ribs) were subjected to the quantitative analysis for the determination of their bioelemental composition. The study has demonstrated that the force needed to brake dura mater or a rib correlates with the content of biological elements in these tissue, as well as with the age and sex of the human subjects serving as teir sources...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29666323/schinzel-giedion-syndrome-a-novel-case-review-and-revised-diagnostic-criteria
#3
Wei-Liang Liu, Zhi-Xu He, Fang Li, Rong Ai, Hong-Wei Ma
Schinzel-Giedion syndrome (SGS) is a rare autosomal dominant inheritance disorder. Heterozygous de novo mutations in the SETBP1 gene have been identified as the genetic cause of SGS. Here, we report a novel case with the syndrome with a novel insertion mutation in SETBP1. We also present a review of SGS cases, and first revise diagnostic criteria of SGS based on clinicalfindings and/or SETBP1 mutation worldwide. A revised diagnostic criteria and typing of SGS can be determined. Type I (complex and classic type) SGS patients present a development delay and typical facial features (prominent forehead, midface retraction, and short and upturned nose) associated with hydronephrosis or two of the characteristic skeletal anomalies (a sclerotic skull base, wideoccipital synchondrosis, increased cortical density or thickness, and broad ribs)...
March 2018: Journal of Genetics
https://www.readbyqxmd.com/read/29665086/severely-impaired-bone-material-quality-in-chihuahua-zebrafish-resembles-classical-dominant-human-osteogenesis-imperfecta
#4
Imke A K Fiedler, Felix N Schmidt, Eva M Wölfel, Christine Plumeyer, Petar Milovanovic, Roberta Gioia, Francesca Tonelli, Hrishikesh A Bale, Katharina Jähn, Roberta Besio, Antonella Forlino, Björn Busse
Excessive skeletal deformations and brittle fractures in the vast majority of patients suffering from osteogenesis imperfecta (OI) are a result of substantially reduced bone quality. Since the mechanical competence of bone is dependent on the tissue characteristics at small length scales, it is of crucial importance to assess how osteogenesis imperfecta manifests at the micro- and nanoscale of bone. In this context, the Chihuahua (Chi/ +) zebrafish, carrying a heterozygous glycine substitution in the α1 chain of collagen type I, has recently been proposed as suitable animal model of classical dominant OI, showing skeletal deformities, altered mineralization patterns and a smaller body size...
April 17, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29659947/pediatric-thoracic-trauma-in-iraq-and-afghanistan
#5
Ryan J Keneally, Cynthia H Shields, Albert Hsu, Howard I Prior, Kevin M Creamer
Introduction: The objective of this study is to review available data on pediatric thoracic trauma seen at U.S. military treatment facilities in Iraq and Afghanistan and describe the scope of injuries, patterns seen, and associated mortality. The results were compared with adults injured in Iraq and Afghanistan and other reports of pediatric thoracic trauma in the literature. Materials and Methods: The investigators received approval from the Uniformed Services University of the Health Sciences' institutional review board before the study...
April 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/29659865/effects-of-a-multi-element-trace-mineral-injection-and-vitamin-e-supplementation-on-performance-carcass-characteristics-and-color-stability-of-strip-steaks-from-feedlot-heifers
#6
B N Harsh, A C Dilger, D D Boler, D W Shike
The objective was to evaluate the interaction of a trace mineral (TM) injection (Multimin 90) and a supranutritional concentration of dietary vitamin E (VITE) on performance, carcass characteristics and color stability of strip steaks from feedlot heifers. Prior to trial initiation, Angus × Simmental cross heifers (N = 48) were managed on a common diet supplemented to meet NRC recommendations (NRC, 2000). Heifers were stratified by BW and allotted to a 2 x 2 factorial arrangement: 1) no supplemental vitamin E and saline injection (CONT+SAL), 2) 1000 IU vitamin E/heifer·d-1 and saline injection (VITE+SAL), 3) no supplemental vitamin E and TM injection (CONT+MM), or 4) vitamin E and TM injection (VITE+MM)...
April 5, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29659567/cytokinin-stabilizes-wuschel-by-acting-on-the-protein-domains-required-for-nuclear-enrichment-and-transcription
#7
Stephen A Snipes, Kevin Rodriguez, Aaron E DeVries, Kaori N Miyawaki, Mariano Perales, Mingtang Xie, G Venugopala Reddy
Concentration-dependent transcriptional regulation and the spatial regulation of transcription factor levels are poorly studied in plant development. WUSCHEL, a stem cell-promoting homeodomain transcription factor, accumulates at a higher level in the rib meristem than in the overlying central zone, which harbors stem cells in the shoot apical meristems of Arabidopsis thaliana. The differential accumulation of WUSCHEL in adjacent cells is critical for the spatial regulation and levels of CLAVATA3, a negative regulator of WUSCHEL transcription...
April 16, 2018: PLoS Genetics
https://www.readbyqxmd.com/read/29657729/risk-factors-for-prolonged-mechanical-ventilation-in-patients-with-severe-multiple-injuries-and-blunt-chest-trauma-a-single-center-retrospective-case-control-study
#8
Yasuyuki Okabe
Aim: Blunt chest trauma is common and is associated with morbidity and mortality in patients with multiple injuries, frequently requiring invasive mechanical ventilation. The aim of this study was to elucidate risk factors for prolonged mechanical ventilation (PMV). Methods: Consecutive adult patients with multiple severe injuries and blunt chest trauma who treated in Chiba Emergency Medical Center (Chiba, Japan) between January 2008 and December 2015 were enrolled in this retrospective chart-review study...
April 2018: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29657333/optimized-arrow-based-mmi-waveguides-for-high-fidelity-excitation-patterns-for-optofluidic-multiplexing
#9
Matthew A Stott, Vahid Ganjalizadeh, Maclain Olsen, Marcos Orfila, Johnny McMurray, Holger Schmidt, Aaron R Hawkins
Multimode interference (MMI) waveguides can be used for multiplexing and de-multiplexing optical signals. High fidelity, wavelength dependent multi-spot patterns from MMI waveguides are useful for sensitive and simultaneous identification of multiple targets in multiplexed fluorescence optofluidic biosensors. Through experiments and simulation, this paper explores design parameters for an MMI rib anti-resonant reflecting optical waveguide (ARROW) in order to produce high fidelity spot patterns at the liquid core biomarker excitation region...
June 2018: IEEE Journal of Quantum Electronics
https://www.readbyqxmd.com/read/29655592/development-of-a-blunt-chest-injury-care-bundle-an-integrative-review
#10
REVIEW
Sarah Kourouche, Thomas Buckley, Belinda Munroe, Kate Curtis
BACKGROUND: Blunt chest injuries (BCI) are associated with high rates of morbidity and mortality. There are many interventions for BCI which may be able to be combined as a care bundle for improved and more consistent outcomes. OBJECTIVE: To review and integrate the BCI management interventions to inform the development of a BCI care bundle. METHODS: A structured search of the literature was conducted to identify studies evaluating interventions for patients with BCI...
April 7, 2018: Injury
https://www.readbyqxmd.com/read/29653069/breathing-exercises-must-be-a-real-and-effective-intervention-to-consider-in-women-with-fibromyalgia-a-pilot-randomized-controlled-trial
#11
Pablo Tomás-Carús, Jaime C Branco, Armando Raimundo, José A Parraca, Nuno Batalha, Clarissa Biehl-Printes
BACKGROUND/OBJECTIVE: Respiratory problems can aggravate pain located in the coincident areas with tender points in the upper half of the body in patients with fibromyalgia (FM) and easily become fatigued, thus can lead to a decrease in the functionality of daily activities. The purpose of this study was to examine the effects of a breathing exercises program on pain thresholds tolerance on tender points and FM impact on daily life. METHODS/DESIGN: Thirty-five women with FM (age 34-67 years) were randomly assigned to an exercise group (n = 18), performing breathing exercises (30 min/session, 7 times/week; for 12 weeks), or to a control group (n = 17)...
April 13, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29653020/developmental-toxicity-of-flucytosine-following-administration-to-pregnant-rats-at-a-specific-time-point-of-organogenesis
#12
Sakiko Fujii, Kaoru Yabe, Yuki Kariwano-Kimura, Masatoshi Furukawa, Kouta Itoh, Masao Matsuura, Masao Horimoto
To investigate the abnormalities that are specific to administration of flucytosine at one time point during embryonic organogenesis, flucytosine was administered orally to pregnant SD rats in a single dose on day 11 of pregnancy at 25 or 35 mg/kg. Fetuses on day 20 of pregnancy were externally, viscerally and skeletally examined. Maternal body weight gain and food consumption were suppressed the day after administration of a 35 mg/kg. Fetal examinations revealed various alterations in both dose groups: externally preaxial polydactyly in the hind limb; skeletally fused lumbar centrum, absent sacral centrum, supernumerary sacral vertebra, and absent ribs...
April 13, 2018: Congenital Anomalies
https://www.readbyqxmd.com/read/29652235/harvey-cushing-s-management-of-neurogenic-thoracic-outlet-syndrome
#13
Courtney Pendleton, Allan J Belzberg, Robert J Spinner, Alfredo Quinones-Hinojosa
Harvey Cushing is widely regarded as one of the forefathers of neurosurgery, and is primarily associated with his work on intracranial pathology. However, he had a clinical and academic interest in peripheral nerve surgery. Through the courtesy of the Alan Mason Chesney Medical Archives, the surgical records of the Johns Hopkins Hospital from 1896 to 1912 were reviewed. The records of a single patient undergoing brachial plexus exploration and cervical rib resection were selected for detailed review. The operative report and accompanying illustrations demonstrate Cushing's interest in adding approaches to the pathology of the brachial plexus to his operative armamentarium...
April 13, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29651513/-chest-trauma-from-a-surgical-perspective
#14
Philipp Lichte, Sebastian Kalverkamp, Jan Spillner, Frank Hildebrand, Philipp Kobbe
Patients with multiple injuries in particular frequently also suffer from chest trauma. During the initial phase the identification and treatment of life-threatening injuries is essential and tension pneumothorax is of particular importance during this phase. The Advanced Trauma Life Support (ATLS) algorithm should be followed for structured treatment. In most cases treatment by insertion of a chest tube is sufficient but for some injuries an emergency thoracotomy is unavoidable as a life-saving intervention...
April 12, 2018: Der Unfallchirurg
https://www.readbyqxmd.com/read/29650420/denosumab-treatment-of-inoperable-or-locally-advanced-giant-cell-tumor-of-bone-multicenter-analysis-outside-clinical-trial
#15
Piotr Rutkowski, Louie Gaston, Aneta Borkowska, Silvia Stacchiotti, Hans Gelderblom, Giacomo Giulio Baldi, Emanuela Palmerini, Paolo Casali, Alessandro Gronchi, Michael Parry, Domenico Andrea Campanacci, Guido Scoccianti, Michal Wagrodzki, Stefano Ferrari, Sander Dijkstra, Andrzej Pieńkowski, Robert Grimer
BACKGROUND: Giant cell tumor of bone (GCTB) is an osteolytic, locally aggressive, rarely metastazing bone tumor. This is a retrospective study evaluating a large series of GCTB patients treated with denosumab in routine practice in 6 European reference centers. METHODS: Patients with locally advanced, unresectable or metastatic GCTB, treated with denosumab outside clinical trials were eligible. Primary end-point was progression-free survival (PFS) for all patients; secondary end-points were: type of surgery, relapse rate and event-free survival for patients after preoperative denosumab + surgery...
March 31, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29649350/evaluation-of-dna-extraction-methods-from-waterlogged-bones-a-pilot-study
#16
Claire Cartozzo, Baneshwar Singh, Edward Boone, Tal Simmons
When deaths occur in water, soft tissue decomposes after a temperature-dependent period, making DNA identification dependent on bone. This study examined the effects of water on bone DNA purity and quantity, and determined the best of three extraction methods for isolating DNA. The organic phenol-chloroform method consistently extracted DNA approximating the accepted 260/280 purity value (~1.8); ChargeSwitch® gDNA Plant Kit and DNeasy Blood and Tissue Kit produced fair and unacceptable values, respectively...
April 12, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29649086/the-morphology-and-clinical-significance-of-the-extraforaminal-ligaments-at-the-t1-t12-levels
#17
Qinghao Zhao, Weicong Zhang, Zhihai Su, Min Wang, Lianjun Yang, Enyi Zhong, Zihai Ding, Qingchu Li, Hai Lu
STUDY DESIGN: A dissection-based study of 10 embalmed human cadavers. OBJECTIVE: The purpose of this study was to describe the extraforaminal ligaments in the exit regions of the T1-T12 intervertebral foramina and to discuss their possible clinical significance. SUMMARY OF BACKGROUND DATA: The ligaments at the lumbar intervertebral foramina have been well studied. However, detailed descriptions of the extraforaminal ligaments at the T1-T12 levels are lacking...
April 11, 2018: Spine
https://www.readbyqxmd.com/read/29644297/negative-pressure-in-treatment-of-persistent-post-traumatic-subcutaneous-emphysema-with-respiratory-failure-case-report-and-literature-review
#18
Jakov Mihanović, Ivan Bačić, Nina Sulen
Subcutaneous emphysema may aggravate traumatic pneumothorax treatment, especially when mechanical ventilation is required. Expectative management usually suffices, but when respiratory function is impaired surgical treatment might be indicated. Historically relevant methods are blowhole incisions and placement of various drains, often with related wound complications. Since the first report of negative pressure wound therapy for the treatment of severe subcutaneous emphysema in 2009, only few publications on use of commercially available sets were published...
February 2018: Trauma Case Reports
https://www.readbyqxmd.com/read/29644288/massive-bilateral-chylothorax-post-blunt-trauma
#19
Christina Kozul, Karishma Jassal, Rodney Judson
Chylothorax caused by blunt trauma is extremely rare. We present a case of bilateral massive chylothorax post blunt trauma and a review of the literature regarding the identification and management of this rare diagnosis. An eighteen-year-old male was involved in a motor vehicle crash where he sustained multiple injuries including a right, moderate to large, haemopneumothorax, a small left haemopneumothorax, left T8, T9, L1 and L2 acute transverse process fractures and fractures of bilateral 11th ribs. An intercostal catheter was inserted on the right side which initially drained blood-stained fluid however milky colour fluid was noted to be draining 11 h post insertion...
December 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29644113/analysis-of-monitored-ground-support-and-rock-mass-response-in-a-longwall-tailgate-entry
#20
G S Esterhuizen, D F Gearhart, I B Tulu
A comprehensive monitoring program was conducted to measure the rock mass displacements, support response, and stress changes at a longwall tailgate entry in West Virginia. Monitoring was initiated a few days after development of the gateroad entries and continued during passage of the longwall panels on both sides of the entry. Monitoring included overcore stress measurements of the initial stress within the rock mass, changes in cable bolt loading, standing support pressure, roof deformation, rib deformation, stress changes in the coal pillar, and changes in the full three-dimensional stress tensor within the rock mass at six locations around the monitoring site...
January 2018: International Journal of Mining Science and Technology
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