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https://www.readbyqxmd.com/read/28203605/femoral-and-tibial-tunnel-diameter-and-bioabsorbable-screw-findings-after-double-bundle-acl-reconstruction-in-5-year-clinical-and-mri-follow-up
#1
Tommi Kiekara, Antti Paakkala, Piia Suomalainen, Heini Huhtala, Timo Järvelä
BACKGROUND: Tunnel enlargement is frequently seen in short-term follow-up after anterior cruciate ligament reconstruction (ACLR). According to new evidence, tunnel enlargement may be followed by tunnel narrowing, but the long-term evolution of the tunnels is currently unknown. HYPOTHESIS/PURPOSE: The hypothesis was that tunnel enlargement is followed by tunnel narrowing caused by ossification as seen in follow-up using magnetic resonance imaging (MRI). The purpose of this study was to evaluate the ossification pattern of the tunnels, the communication of the 2 femoral and 2 tibial tunnels, and screw absorption findings in MRI...
February 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28183636/improved-tympanic-membrane-regeneration-after-myringoplastic-surgery-using-an-artificial-biograft
#2
A P S Immich, P C Pennacchi, A F Naves, S L Felisbino, R L Boemo, S S Maria-Engler, L H Catalani
Tympanic membrane perforations are due to common otologic problems. The current treatments to heal tympanic membrane perforation, such as myringoplasty, have some disadvantages, including the need for autologous grafting, which is rapidly absorbed by the organism before perforation recovery is complete. To improve the structural and functional tympanic membrane healing after surgery, we propose a new branch of artificial grafts. In this study, we report the development of artificial grafts using electrospun bioabsorbable polymers...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28181795/water-responsive-shape-recovery-induced-buckling-in-biodegradable-photo-cross-linked-poly-ethylene-glycol-peg-hydrogel
#3
Abhijit Vijay Salvekar, Wei Min Huang, Rui Xiao, Yee Shan Wong, Subbu S Venkatraman, Kiang Hiong Tay, Ze Xiang Shen
The phenomenon of recovering the permanent shape from a severely deformed temporary shape, but only in the presence of the right stimulus, is known as the shape memory effect (SME). Materials with such an interesting effect are known as shape memory materials (SMMs). Typical stimuli to trigger shape recovery include temperature (heating or cooling), chemical (including water/moisture and pH value), and light. As a SMM is able not only to maintain the temporary shape but also to respond to the right stimulus when it is applied, via shape-shifting, a seamless integration of sensing and actuation functions is achieved within one single piece of material...
February 9, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28160103/stents-biomechanics-biomaterials-and-insights-from-computational-modeling
#4
REVIEW
Georgia S Karanasiou, Michail I Papafaklis, Claire Conway, Lampros K Michalis, Rami Tzafriri, Elazer R Edelman, Dimitrios I Fotiadis
Coronary stents have revolutionized the treatment of coronary artery disease. Improvement in clinical outcomes requires detailed evaluation of the performance of stent biomechanics and the effectiveness as well as safety of biomaterials aiming at optimization of endovascular devices. Stents need to harmonize the hemodynamic environment and promote beneficial vessel healing processes with decreased thrombogenicity. Stent design variables and expansion properties are critical for vessel scaffolding. Drug-elution from stents, can help inhibit in-stent restenosis, but adds further complexity as drug release kinetics and coating formulations can dominate tissue responses...
February 3, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28146023/effective-repair-of-dural-tear-using-bioabsorbable-sheet-with-fibrin-glue
#5
Akira Iwata, Masahiko Takahata, Ken Kadoya, Hideaki Sudo, Terufumi Kokabu, Katsuhisa Yamada, Norimasa Iwasaki
STUDY DESIGN: Basic Science OBJECTIVE.: This study aimed to compare the techniques of surgical repair of dural tear using bioabsorbable material and fibrin glue. SUMMARY OF BACKGROUND DATA: Cerebrospinal fluid (CSF) leakage caused by dural tear can often be difficult to manage even after repair when the same materials are used in a similar manner. METHODS: Burst pressure was measured for repaired porcine dura with holes of different diameters using spray of combined fibrinogen and thrombin solution (fibrin spray) alone as a control and the 5-mm hole following different methods using fibrinogen and thrombin solutions plus polyglactin 910 sheet (PGS)...
January 31, 2017: Spine
https://www.readbyqxmd.com/read/28140661/fabrication-and-characterization-of-shape-memory-polymers-based-bioabsorbable-biomedical-drug-eluting-stent
#6
Vratika C Sonawane, Mahesh P More, Abhijeet P Pandey, Pravin O Patil, Prashant K Deshmukh
Present investigation deals with, tacrolimus eluting, self-expandable, biodegradable stent fabricated by solvent casting method. The design was based on shape memory polymers, which possess the ability to memorize temporary shape that can substantially differ from their initial permanent shape. A set of biodegradable polymers blend was used such as poly-lactic acid (PLA) and poly-l-glycolic acid (PLGA) to study the shape memory effect of polymer. The prepared stent was assessed for various parameters like Scanning Electron Microscopy (SEM), In-vitro and Ex vivo expansion, Drug content, In-vitro drug release, Haemocompatibility, Differential Scanning Calorimetry (DSC), Fourier Transform Infrared spectroscopy (FTIR), and Textural Characterization...
January 31, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28130871/evaluation-of-wrought-zn-al-alloys-1-3-and-5-wt-al-through-mechanical-and-in-vivo-testing-for-stent-applications
#7
Patrick K Bowen, Jan-Marten Seitz, Roger J Guillory, Jacob P Braykovich, Shan Zhao, Jeremy Goldman, Jaroslaw W Drelich
Special high grade zinc and wrought zinc-aluminum (Zn-Al) alloys containing up to 5.5 wt % Al were processed, characterized, and implanted in rats in search of a new family of alloys with possible applications as bioabsorbable endovascular stents. These materials retained roll-induced texture with an anisotropic distribution of the second-phase Al precipitates following hot-rolling, and changes in lattice parameters were observed with respect to Al content. Mechanical properties for the alloys fell roughly in line with strength (190-240 MPa yield strength; 220-300 MPa ultimate tensile strength) and elongation (15-30%) benchmarks, and favorable elastic ranges (0...
January 27, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28128890/design-of-a-bioabsorbable-multilayered-patch-for-esophagus-tissue-engineering
#8
Rossella Dorati, Antonella De Trizio, Stefania Marconi, Anna Ferrara, Ferdinando Auricchio, Ida Genta, Tiziana Modena, Marco Benazzo, Alberto Benazzo, Gino Volpato, Bice Conti
A gold standard for esophagus reconstruction is not still available. The present work aims to design a polymer patch combining synthetic polylactide-co-polycaprolacton and chitosan biopolymers, tailoring patch properties to esophageal tissue characteristics by a temperature-induced precipitation method, to get multilayered patches (1L, 2L, and 3L). Characterization shows stable multilayered patches (1L and 2L) by selection of copolymer type, and their M w . In vitro investigation of the functional patch properties in simulated physiologic and pathologic conditions demonstrates that the chitosan layer (patch 3L) decreases patch stability and cell adhesion, while improves cell proliferation...
January 27, 2017: Macromolecular Bioscience
https://www.readbyqxmd.com/read/28104093/surgical-management-of-delayed-irreducible-gartland-iii-supracondylar-fractures-in-children-open-reduction-and-internal-fixation-versus-external-fixation
#9
Jin Li, DeHao Fu, Chong Yu, ShangYu Wang, RenHao Ze, Xin Tang
BACKGROUND: Percutaneous pinning has been accepted as the "gold standard" for displaced supracondylar humeral fracture (SHF) in children. However, to secure an anatomic reduction and to reduce the rotated fragment, open reduction is often necessary when there is inadequate stabilization or a satisfactory reduction has failed to be achieved. The study aimed to compare the efficacy of the open reduction and bioabsorbable poly-d,l-lactic acid (PDLLA) pin fixation method with the closed reduction and lateral external fixation method in irreducible delayed Gartland type III SHF in children...
February 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28066530/play-hands-protective-gloves-technical-note-on-design-and-concept
#10
Michele Houston-Hicks, Derek J Lura, M Jason Highsmith
Cerebral Palsy (CP) is the leading cause of childhood motor disability, with a global incidence of 1.6 to 2.5/1,000 live births. Approximately 23% of children with CP are dependent upon assistive technologies. Some children with developmental disabilities have self-injurious behaviors such as finger biting but also have therapeutic needs. The purpose of this technical note is to describe design considerations for a protective glove and finger covering that maintains finger dexterity for children who exhibit finger and hand chewing (dermatophagia) and require therapeutic range of motion and may benefit from sensory stimulation resulting from constant contact between glove and skin...
September 2016: Technology and Innovation
https://www.readbyqxmd.com/read/28062841/metal-based-superoxide-dismutase-and-catalase-mimics-reduce-oxidative-stress-biomarkers-and-extend-life-span-of-saccharomyces-cerevisiae
#11
Thales de P Ribeiro, Fernanda L Fonseca, Mariana D C de Carvalho, Rodrigo M da C Godinho, Fernando Pereira de Almeida, Tatiana D Saint'Pierre, Nicolás A Rey, Christiane Fernandes, Adolfo Horn, Marcos D Pereira
Aging is a natural process characterized by several biological changes. In this context, oxidative stress appears as a key factor that leads cells and organisms to severe dysfunctions and diseases. To cope with reactive oxygen species and oxidative-related damage, there has been increased use of superoxide dismutase (SOD)/catalase (CAT) biomimetic compounds. Recently, we have shown that three metal-based compounds {[Fe(HPClNOL)Cl2]NO3, [Cu(HPClNOL)(CH3CN)](ClO4)2 and Mn(HPClNOL)(Cl)2}, harboring in vitro SOD and/or CAT activities, were critical for protection of yeast cells against oxidative stress...
January 15, 2017: Biochemical Journal
https://www.readbyqxmd.com/read/28046765/su-f-t-49-dosimetry-parameters-and-tps-commissioning-for-the-civasheet-directional-pd-103-brachytherapy-source
#12
M J Rivard
PURPOSE: The CivaSheet is a new LDR Pd-103 brachytherapy device offering directional-radiation for preferentially irradiating malignancies with healthy-tissue sparing. Observations are presented on dosimetric characterization, TPS commissioning, and evaluation of the dosesuperposition- principle for summing individual elements comprising a planar CivaSheet METHODS: The CivaSheet comprises individual sources (CivaDots, 0.05cm thick and 0.25cm diam.) inside a flexible bioabsorbable substrate with a 0...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28024575/effect-of-mg-content-on-the-thermal-stability-and-mechanical-behaviour-of-plla-mg-composites-processed-by-hot-extrusion
#13
S C Cifuentes, M Lieblich, F A López, R Benavente, J L González-Carrasco
In the field of bioabsorbable composites for biomedical applications, extrusion has been employed as a method to prepare homogeneous blends of polymeric matrices with bioactive ceramic fillers. In this work, the suitability of processing poly-l-lactic acid/Magnesium (PLLA/Mg) composites by hot extrusion has been assessed by a systematic characterization of PLLA/Mg composites containing different amounts of Mg particles up to 7wt%. The results show that extrusion causes a reduction of almost 20% in the viscosity average molecular weight of PLLA, which further decreases with increasing Mg content...
March 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28017123/current-state-of-bioabsorbable-polymer-coated-drug-eluting-stents
#14
Akinapelli Absdhilash, Jack P Chen, Kristine Roy, Joseph Donnelly, Keith Dawkins, Barbara Huibregtse, Dongming Hou
Drug-eluting stents (DES) have been shown to significantly reduce clinical and angiographic restenosis compared to bare metal stents (BMS). The polymer coatings on DES elute antiproliferative drugs to inhibit intimal proliferation and prevent restenosis after stent implantation. Permanent polymers which do not degrade in vivo may increase the likelihood of stent-related delayed arterial healing or polymer hypersensitivity. In turn, these limitations may contribute to an increased risk of late clinical events...
December 22, 2016: Current Cardiology Reviews
https://www.readbyqxmd.com/read/28009728/medical-and-economic-evaluation-of-foreseal-bioabsorbable-reinforcement-sleeves-compared-with-current-standard-of-care-for-reducing-air-leakage-duration-after-lung-resection-for-malignancy-a-randomized-trial
#15
Marco Alifano, Christophe Jayle, François Bertin, Pierre Magdeleinat, Yves Castier, Olivier Tiffet, Alain Bernard, François Tronc, Pierre-Yves Brichon, Pascal Dumont, Gilles Grosdidier, Antoine Dujon, Abel Grine, Helena Pereira, Anais Le Jeannic, Marie Amélie Vinet, Hassani MaOulida, Isabelle Durand-Zaleski, Marc Riquet, Gilles Chatellier, Jean-François Regnard
OBJECTIVE: The objective of this study was to determine the efficacy of alginate staple-line reinforcement of fissure openings as compared with stapling alone, with or without tissue sealant or glue, in reducing the incidence and duration of air leakage after pulmonary lobectomy for malignancy. SUMMARY BACKGROUND DATA: No randomized trial evaluating alginate staple-line reinforcement has been performed to date. METHODS: The Staple-line Reinforcement for Prevention of Pulmonary Air Leakage study was a multicenter randomized trial, with blinded evaluation of endpoints...
January 2017: Annals of Surgery
https://www.readbyqxmd.com/read/27989342/comparison-of-suture-based-anchors-and-traditional-bioabsorbable-anchors-in-foot-and-ankle-surgery
#16
W Chad Hembree, Michael A Tsai, Brent G Parks, Stuart D Miller
We compared the pullout strength of a suture-based anchor versus a bioabsorbable anchor in the distal fibula and calcaneus and evaluated the relationship between bone mineral density and peak load to failure. Eight paired cadaveric specimens underwent a modified Broström procedure and Achilles tendon reattachment. The fibula and calcaneus in the paired specimens received either a suture-based anchor or a bioabsorbable suture anchor. The fibular and calcaneal specimens were loaded to failure, defined as a substantial decrease in the applied load or pullout from the bone...
January 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/27987754/incorporation-of-biguanide-compounds-into-poly-gl-b-poly-gl-co-tmc-co-cl-b-poly-gl-monofilament-surgical-sutures
#17
Yolanda Márquez, Tània Cabral, Alice Lorenzetti, Lourdes Franco, Pau Turon, Luís J Del Valle, Jordi Puiggalí
A new biodegradable coating was developed for bioabsorbable monofilament sutures. Specifically, a random copolymer having 35wt-% and 65wt-% of lactide and trimethylene carbonate units showed appropriate flexibility, stickiness and degradation rate, as well as capability to produce a complete and uniform coating. Monofilament sutures of polyglycolide-b-poly(glycolide-co-trimethylene carbonate-co-ε-caprolactone)-b-polyglycolide were loaded with chlorhexidine (CHX) and poly(hexamethylene biguanide) (PHMB) to explore the possibility to achieve antimicrobial activity without adverse cytotoxic effects...
February 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27984690/-pretibial-pseudocyst-after-anterior-cruciate-ligament-reconstruction-with-a-biocomposite-screw
#18
B Alonso, F B Sobrón, C Vidal, J Vaquero
We report the case of a patient who presented a pretibial extra-articular cyst two years after an arthroscopically assisted ACL reconstruction using an autologous bone-patellar tendon-bone graft. The tibial fixation was achieved with a bioabsorbable screw made of poly-L, D-lactic and -tricalcium phosphate (-TCP). A subcutaneous pseudocystic lesion was excised. It consisted of a capsular fibrous tissue with minimal milky fluid (1 ml) centrally. It penetrated into the tibial tunnel but did not communicate with the knee joint space...
May 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/27974669/initial-experience-of-bioabsorbable-polymer-everolimus-eluting-synergy-stents-in-high-risk-patients-undergoing-complex-percutaneous-coronary-intervention-with-early-discontinuation-of-dual-antiplatelet-therapy
#19
Rebecca L Noad, Colm G Hanratty, Simon J Walsh
AIMS: As more elderly and co-morbid patients require percutaneous revascularization, 1 year of dual-antiplatelet therapy (DAPT) becomes concerning. Synergy stents (Boston Scientific) allow for early cessation of DAPT. This study assessed those in our unit who underwent percutaneous coronary intervention (PCI) with a Synergy stent to examine a minimum of 6 months of clinical outcomes after early discontinuation of DAPT. METHODS AND RESULTS: All non-trial patients in our unit who had PCI with a Synergy stent from August 2013 to February 2016 were retrospectively analyzed...
February 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27969760/tct-410-different-vascular-healing-process-between-bioabsorbable-polymer-coated-everolimus-eluting-stents-versus-bioresorbable-vascular-scaffolds-via-optical-coherence-tomography-and-coronary-angioscopy-early-results-from-endothelial-healing-assessment-with
#20
Wan Azman Wan Ahmad, Takaharu Nakayoshi, Ahmad Syadi Mahmood Zuhdi, Muhammad Dzafir Ismail, Yoshihiro Fukumoto, Takafumi Ueno
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
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