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Psychiatric Assessments

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https://www.readbyqxmd.com/read/28822801/microarray-gene-expression-study-in-fibroblast-and-lymphoblastoid-cell-lines-from-antipsychotic-na%C3%A3-ve-first-episode-schizophrenia-patients
#1
Patricia Gassó, Sergi Mas, Natalia Rodríguez, Daniel Boloc, Susana García-Cerro, Miquel Bernardo, Amalia Lafuente, Eduard Parellada
Schizophrenia (SZ) is a chronic psychiatric disorder whose onset of symptoms occurs in late adolescence and early adulthood. The etiology is complex and involves important gene-environment interactions. Microarray gene-expression studies on SZ have identified alterations in several biological processes. The heterogeneity in the results can be attributed to the use of different sample types and other important confounding factors including age, illness chronicity and antipsychotic exposure. The aim of the present microarray study was to analyze, for the first time to our knowledge, differences in gene expression profiles in 18 fibroblast (FCLs) and 14 lymphoblastoid cell lines (LCLs) from antipsychotic-naïve first-episode schizophrenia (FES) patients and healthy controls...
August 5, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28822681/firearm-storage-practices-in-households-of-adolescents-with-and-without-mental-illness
#2
Joseph A Simonetti, Mary Kay Theis, Ali Rowhani-Rahbar, Evette J Ludman, David C Grossman
PURPOSE: Safe firearm storage practices are associated with a lower risk of self-inflicted injury and death. Whether such practices and relevant beliefs differ between households of adolescents with and without mental illness is unknown. METHODS: We used survey and administrative data to perform a two-stage cross-sectional study of parents/guardians of adolescents who were 11-17 years, enrolled in a managed care plan in 2004 and living in a household with a firearm...
August 16, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28821287/physical-activity-and-quality-of-life-in-long-term-hospitalized-patients-with-severe-mental-illness-a-cross-sectional-study
#3
Jeroen Deenik, Frank Kruisdijk, Diederik Tenback, Annemarie Braakman-Jansen, Erik Taal, Marijke Hopman-Rock, Aartjan Beekman, Erwin Tak, Ingrid Hendriksen, Peter van Harten
BACKGROUND: Increasing physical activity in patients with severe mental illness is believed to have positive effects on physical health, psychiatric symptoms and as well quality of life. Till now, little is known about the relationship between physical activity and quality of life in long-term hospitalized patients with severe mental illness and knowledge of the determinants of behavioural change is lacking. The purpose of this study was to elucidate the relationship between objectively measured physical activity and quality of life, and explore modifiable psychological determinants of change in physical activity in long-term hospitalized patients with severe mental illness...
August 18, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28820772/the-individual-experience-of-aging-patients-and-the-current-service-provision-in-the-context-of-italian-forensic-psychiatry-a-case-study
#4
Claudio Di Lorito, Luca Castelletti, Giuseppa Tripi, Maria Gloria Gandellini, Tom Dening, Birgit Völlm
INTRODUCTION: After the recent development of residential units for the execution of security measures managed by the National Health Service and the closing down of forensic psychiatric hospitals, no study has been conducted to investigate the individual experience of aging patients and to assess whether the new service is adequately meeting their needs. We aimed to explore the experience of the service of a sample of patients aged 50 years and above living in one of the Italian residential units for the execution of security measures...
July 2017: Journal of Forensic Nursing
https://www.readbyqxmd.com/read/28820354/validity-of-screening-for-psychiatric-disorders-in-unaccompanied-minor-asylum-seekers-use-of-computer-based-assessment
#5
Marianne Jakobsen, Melinda A Meyer DeMott, Trond Heir
Self-report screening is an important element of transcultural research. Problems concerning illiteracy, cultural sensitivity, and possible misunderstandings have been handled differently in different settings. The aim of this study was to evaluate the validity of two well-known instruments: the Hopkins Symptoms Check List (HSCL-25), and the Harvard Trauma Questionnaire (HTQ, Part IV), with a sample of 160 unaccompanied asylum-seeking adolescents from Afghanistan and Somalia. Assessments were performed 4 months after arrival in Norway, and the screening instruments were presented to the informants on computers with touch-screen function, using the program MultiCASI...
January 1, 2017: Transcultural Psychiatry
https://www.readbyqxmd.com/read/28819480/-an-unusual-intraurethral-foreign-body-a-case-report
#6
Hicham El Bote, Ernest Hage, Rami Fares
In medical literature there are several case reports of foreign bodies introduced into the urethra. Foreign bodies are usually inserted as result of erotic activities, psychiatric disorders and, rarely, in an attempt to evacuate the urine. Diagnosis is based on clinical examination and imaging tests. Endoscopic management is the treatment of choice but, in some cases, open surgery may be necessary. The therapeutic approach should be systematically complemented by a psychiatric assessment of the patient. We report the case a 64-year old man with a personal history of behavioral disorders who introduced an electric wire in his urethra...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28818735/prospective-assessment-of-social-network-quality-among-depressed-mothers-treated-with-brief-psychotherapy-the-social-network-quality-snq-scales
#7
Luis E Flores, Jill M Cyranowski, Marlissa Amole, Holly A Swartz
OBJECTIVE: Social relationships play important roles in emotional health, and are common targets of psychotherapeutic interventions. To better evaluate social relationship structure and function in the context of psychotherapy trials, this study introduces and psychometrically evaluates the Social Network Quality (SNQ) scales, which supplement the Social Network Index (SNI). The original SNI evaluates social network structure (i.e., extent of participation in diverse social roles and number of social relationships)...
July 20, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28818166/assessment-of-quality-of-sleep-and-its-relationship-with-psychiatric-morbidity-and-socio-demographic-factors-in-the-patients-of-chronic-renal-disease-undergoing-hemodialysis
#8
Usama Bin Zubair, Batool Butt
OBJECTIVE: To assess the subjective sleep quality and its relationship with the presence of psychiatric morbidity in the patients suffering from chronic kidney disease (CKD) and undergoing the procedure of hemodialysis (HD); and analyze the associated socio-demographic factors. STUDY DESIGN: Cross-sectional descriptive study. PLACE AND DURATION OF STUDY: Nephrology Department, Military Hospital, Rawalpindi, from July to December 2016. METHODOLOGY: Patients of CKD undergoing the HD were included in the final analysis...
July 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28817766/characteristics-and-risk-factors-for-negative-academic-events-a-27-year-serial-prevalence-study-of-9-7-million-japanese-college-students
#9
Chiyoko Uchida, Mai Uchida
Objective: To examine the prevalence of and the factors contributing to leaves of absence and school discontinuation in Japanese college students over a 27-year period. Trends in these academic events over time were assessed, and students at elevated risk and psychosocial difficulties in need of supportive intervention were identified. Methods: Surveys were collected from the majority of Japanese national universities between 1985 and 2012, yielding data on a total of 9...
August 10, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/28817764/limited-functioning-after-remission-of-an-anxiety-disorder-as-a-trait-effect-versus-a-scar-effect-results-of-a-longitudinal-general-population-study
#10
Simone M E Schopman, Margreet Ten Have, Saskia van Dorsselaer, Ron de Graaf, Neeltje M Batelaan
OBJECTIVE: After remission of an anxiety disorder, subjects often experience persistent functional impairments. We examined whether impairments in mental and physical functioning following remission are a continuation of premorbid lower functioning (trait effect), due to impairments that develop during the anxiety disorder and persist beyond recovery (scar effect), or both. METHODS: Data were derived from the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2), a prospective psychiatric epidemiologic study among the general population with a 3-wave design (6-year follow-up, with the study starting in 2007 and ending in 2015)...
August 15, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28816913/influence-of-written-informed-consent-for-methylphenidate-on-medicine-persistence-rates-in-children-with-attention-deficit-hyperactivity-disorder
#11
Kristian Naenen-Hernani, Antonio Palazón-Bru, Francisco Colomina-Climent, Vicente F Gil-Guillén
OBJECTIVE: To assess the influence of written informed consent on nonpersistence with methylphenidate treatment in children with attention-deficit hyperactivity disorder (ADHD). METHODS: We undertook a cohort study including 141 children with ADHD who started treatment with methylphenidate, with a follow-up of 6 months. The main outcome variable was nonpersistence, defined as discontinuation of treatment by the patient. Two groups were analyzed with and without written informed consent...
August 9, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28816883/cerebral-oxygen-saturation-during-electroconvulsive-therapy-a-secondary-analysis-of-a-randomized-crossover-trial
#12
Kamath Sriganesh, Tanmay Jadhav, Sudhir Venkataramaiah, Channaveerachari Naveen Kumar, Shyamsundar Armugham, Mariamma Philip, K R Madhusudan Reddy, Jagadisha Thirthalli, G S Umamaheswara Rao
BACKGROUND: Electroconvulsive therapy (ECT) causes acute changes in cerebral perfusion and oxygenation. Near-infrared spectroscopy is a novel, noninvasive technique to assess cerebral oxygen saturation (cSO2). We hypothesized that cSO2 increases during ECT and more so with atropine premedication and decreases when systemic desaturation (peripheral oxygen saturation <90%) occurs during ECT. METHODS: We performed a secondary analysis of a randomized trial of patients undergoing ECT for psychiatric illness during a 6-month period...
August 14, 2017: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/28816791/resting-state-functional-connectivity-in-the-human-connectome-project-current-status-and-relevance-to-understanding-psychopathology
#13
Deanna M Barch
A key tenet of modern psychiatry is that psychiatric disorders arise from abnormalities in brain circuits that support human behavior. Our ability to examine hypotheses around circuit-level abnormalities in psychiatric disorders has been made possible by advances in human neuroimaging technologies. These advances have provided the basis for recent efforts to develop a more complex understanding of the function of brain circuits in health and of their relationship to behavior-providing, in turn, a foundation for our understanding of how disruptions in such circuits contribute to the development of psychiatric disorders...
August 16, 2017: Harvard Review of Psychiatry
https://www.readbyqxmd.com/read/28816508/stability-and-predictive-validity-of-the-parent-child-sleep-interactions-scale-a-longitudinal-study-among-preschoolers
#14
Chelsey S Barrios, Samantha Y Jay, Victoria C Smith, Candice A Alfano, Lea R Dougherty
Little research has examined the processes underlying children's persistent sleep problems and links with later psychopathology. The current study examined the stability of parent-child sleep interactions as assessed with the parent-reported Parent-Child Sleep Interactions Scale (PSIS) and examined whether sleep interactions in preschool-age children predict sleep problems and psychiatric symptoms later in childhood. Participants included 108 preschool-age children (50% female) and their parents. Parents completed the PSIS when children were 3-5 years (T1) and again when they were 6-9 years (T2)...
August 17, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28816466/a-comparison-of-psychopathology-and-reoffending-in-female-and-male-convicted-firesetters
#15
Lauren Ducat, Troy McEwan, James R P Ogloff
Little is known about the psychopathological or criminal history characteristics of female firesetters, or how often women reoffend by firesetting. The current study is one of the few large-scale longitudinal investigations to compare key psychiatric and offending variables in female and male firesetters who are not incarcerated or known to be mentally disordered. In addition, the study aimed to identify the base rate of recidivism for female firesetters compared with males. The study compared all 143 female and 909 male firesetters convicted of arson and fire-related offenses between 2000 and 2009 in Victoria, Australia...
August 17, 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/28816242/effect-of-the-mglur5-nam-basimglurant-on-behavior-in-adolescents-and-adults-with-fragile-x-syndrome-in-a-randomized-double-blind-placebo-controlled-trial-fragxis-phase-2-results
#16
Eriene A Youssef, Elizabeth Berry-Kravis, Christian Czech, Randi J Hagerman, David Hessl, Chin Y Wong, Michael Rabbia, Dennis Deptula, Amy John, Russell Kinch, Philip Drewitt, Lothar Lindemann, Moritz Marcinowski, Rachel Langland, Carsten Horn, Paulo Fontoura, Luca Santarelli, Jorge A Quiroz
Preclinical data suggests that inhibition of the mGluR5 receptor might hold therapeutic benefits in Fragile X syndrome (FXS). Treatment of Fmr1 knockout mice with mGluR5-negative allosteric modulators (NAMs) has been reported to correct a broad range of phenotypes related to FXS. The early short-term clinical trials with mGluR5 NAMs, including basimglurant, assessing the effects in individuals with FXS, were supportive of further exploration in larger, well-controlled trials. We evaluated basimglurant, a potent and selective mGluR5 NAM, in a 12-week, double-blind, parallel-group study of 183 adults and adolescents (aged 14-50, mean 23...
August 17, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28815738/the-effect-of-depression-generalized-anxiety-and-selective-serotonin-reuptake-inhibitors-on-change-in-bone-metabolism-in-adolescents-and-emerging-adults
#17
Chadi A Calarge, James A Mills, Kathleen F Janz, Trudy L Burns, Janet A Schlechte, William H Coryell, Babette S Zemel
OBJECTIVES: To prospectively examine the independent contribution of major depressive disorder (MDD), generalized anxiety disorder (GAD), and selective serotonin reuptake inhibitors (SSRIs) use to changes in bone metabolism in older adolescents and emerging adults. METHODS: Medically-healthy 15 to 20 year-olds who were unmedicated or within one month of starting an SSRI were prospectively followed. Psychiatric functioning and medication treatment were assessed monthly...
August 16, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28815619/sluggish-cognitive-tempo-in-children-and-adolescents-with-higher-functioning-autism-spectrum-disorders-social-impairments-and-internalizing-symptoms
#18
Outi Reinvall, Teija Kujala, Arja Voutilainen, Anu-Liisa Moisio, Pekka Lahti-Nuuttila, Marja Laasonen
Sluggish cognitive tempo (SCT) was introduced in 1980s in the field of attention deficit hyperactivity disorder (ADHD). Studies indicate that symptoms of SCT are separate from symptoms of ADHD and independently associated with multiple domains of functioning in clinical groups and in typical development. We assessed whether similar pattern would apply to higher functioning autism spectrum disorders (ASD). Children with higher functioning ASD (N = 55; 5-15 years) were divided into the ASD+High SCT (n = 17), the ASD+Medium SCT (n = 18) and the ASD+Low SCT (n = 20) groups based on parent-rated daydreaming and slowness on the Five to Fifteen questionnaire (FTF)...
August 16, 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/28815114/an-exploration-of-latent-structure-in-observational-huntington-s-disease-studies
#19
Soumya Ghosh, Zhaonan Sun, Ying Li, Yu Cheng, Amrita Mohan, Cristina Sampaio, Jianying Hu
Huntington's disease (HD) is a monogenic neurodegenerative disorder characterized by the progressive decay of motor and cognitive abilities accompanied by psychiatric episodes. Tracking and modeling the progression of the multi-faceted clinical symptoms of HD is a challenging problem that has important implications for staging of HD patients and the development of improved enrollment criteria for future HD studies and trials. In this paper, we describe the first steps towards this goal. We begin by curating data from four recent observational HD studies, each containing a diverse collection of clinical assessments...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28814874/la-belle-indiff%C3%A3-rence-revisited-a-case-report-on-progressive-supranuclear-palsy-misdiagnosed-as-conversion-disorder
#20
Petra J van Meerkerk-Aanen, Lars de Vroege, David Khasho, Aziza Foruz, J Thies van Asseldonk, Christina M van der Feltz-Cornelis
BACKGROUND: Since the advent of computed tomography and magnetic resonance imaging scans, neurological disorders have less often been falsely labeled as conversion disorder (CD). However, misdiagnosis of a neurological disorder as CD still occurs, especially in cases with insidious onset. Misinterpretation of la belle indifférence may contribute to such misdiagnosis. Here, we describe a case of progressive supranuclear palsy/Richardson's syndrome (PSPS) misdiagnosed as a case of CD. CASE: A 62-year-old woman consulted two different neurologists in 2012 because of falling spells since 2009 and was diagnosed with CD...
2017: Neuropsychiatric Disease and Treatment
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