keyword
MENU ▼
Read by QxMD icon Read
search

Wound closure

keyword
https://www.readbyqxmd.com/read/29235007/snapshot-study-on-the-value-of-omentoplasty-in-abdominoperineal-resection-with-primary-perineal-closure-for-rectal-cancer
#1
Robin D Blok, Gijsbert D Musters, Wernard A A Borstlap, Christianne J Buskens, Wilhelmus A Bemelman, Pieter J Tanis
BACKGROUND: Perineal wound complications are often encountered following abdominoperineal resection (APR). Filling of the pelvic space by omentoplasty (OP) might prevent these complications, but there is scant evidence to support its routine application. OBJECTIVE: The aim of this study was to evaluate the impact of OP on perineal wound complications. METHODS: All patients undergoing APR with primary perineal closure (PPC) for non-locally advanced rectal cancer in 71 Dutch centers in 2011 were selected from a cross-sectional snapshot study...
December 12, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29233507/bleeding-on-the-cutting-edge-a-systematic-review-of-anticoagulant-and-antiplatelet-continuation-in-minor-cutaneous-surgery
#2
REVIEW
Alexander Isted, Lilli Cooper, R James Colville
BACKGROUND: Anticoagulant and antiplatelet (AC/AP) use is common and practice surrounding AC/AP continuation or cessation peri-operatively for minor cutaneous surgery lacks evidence-based consensus. OBJECTIVE: To determine the risks of haemorrhagic and thromboembolic complications associated with the continuation or cessation of AC/AP therapy in minor cutaneous surgery. METHODS: A systematic literature search was conducted using PubMed, MEDLINE, Embase and CENTRAL, to identify all articles involving the use of AC/AP in patients undergoing minor cutaneous surgery, including skin grafts and local flaps...
November 28, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29232903/pediatric-thermal-burns-and-treatment-a-review-of-progress-and-future-prospects
#3
REVIEW
Elton Mathias, Madhu Srinivas Murthy
Burn injuries are a devastating critical care problem. In children, burns continue to be a major epidemiologic problem around the globe resulting in significant morbidity and death. Apparently, treating these burn injuries in children and adults remains similar, but there are significant physiological and psychological differences. The dermal layer of the skin is generally thinner in neonates, infants, and children than in adults. Enhanced evaporative loss and need for isotonic fluids increases the risk of hypothermia in the pediatric population...
December 11, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/29232685/surgical-management-of-deep-brain-stimulator-scalp-erosion-without-hardware-removal
#4
Michael D Staudt, Navid Pourtaheri, Gregory E Lakin, Hooman T Soltanian, Jonathan P Miller
BACKGROUND: Scalp erosion in patients with deep brain stimulation (DBS) hardware is an uncommon complication that lacks a clearly defined management strategy. Previous studies have described various therapies including conservative treatment with antibiotics and surgical debridement with or without hardware removal. OBJECTIVES: The aim of this study was to review the efficacy of a hardware-sparing management strategy for the treatment of scalp erosion. METHODS: Five patients with previous DBS implantation presented with scalp erosion and visible hardware exposure at the calvarial burr hole site, and underwent tension-free, vascularized, rotational scalp flap, with preservation of the leads under the pericranium...
December 13, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/29229785/the-chemokine-receptor-cx3cr1-coordinates-monocyte-recruitment-and-endothelial-regeneration-after-arterial-injury
#5
Tobias Getzin, Kashyap Krishnasamy, Jaba Gamrekelashvili, Tamar Kapanadze, Anne Limbourg, Christine Häger, L Christian Napp, Johann Bauersachs, Hermann Haller, Florian P Limbourg
Regeneration of arterial endothelium after injury is critical for the maintenance of normal blood flow, cell trafficking, and vascular function. Using mouse models of carotid injury, we show that the transition from a static to a dynamic phase of endothelial regeneration is marked by a strong increase in endothelial proliferation, which is accompanied by induction of the chemokine CX3CL1 in endothelial cells near the wound edge, leading to progressive recruitment of Ly6Clo monocytes expressing high levels of the cognate CX3CR1 chemokine receptor...
December 11, 2017: EMBO Molecular Medicine
https://www.readbyqxmd.com/read/29229138/abdominal-wall-reconstruction-after-cytoreduction-surgery-hyperthermic-intraperitoneal-chemotherapy
#6
Anthony J Scholer, Joseph B Oliver, Jesus Rosado, Jimmy S Patel, Lindsay J Lynch, Kevin M Spiegler, Karen Houck, Ravi J Chokshi
BACKGROUND: Cytoreduction surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) improve survival and decrease recurrence of peritoneal metastasis in a select population of patients. Abdominal wall resection is often needed to achieve complete CRS and the extent of abdominal wall resection may necessitate abdominal wall reconstruction (AWR). We sought to investigate if postoperative morbidity and mortality was increased in patients who underwent AWR with CRS-HIPEC (AWR group) compared to CRS-HIPEC without AWR (non-AWR group) and to identify if patient, tumor, and operative risk factors were associated with poor outcomes following AWR...
January 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29229125/efficacy-of-the-dual-controlled-release-of-hgf-and-bfgf-impregnated-with-a-collagen-gelatin-scaffold
#7
Shuichi Ogino, Naoki Morimoto, Michiharu Sakamoto, Chizuru Jinno, Yuki Sakamoto, Tsuguyoshi Taira, Shigehiko Suzuki
BACKGROUND: We previously developed collagen/gelatin sponges (CGS) able to sustain and release basic fibroblast growth factor (bFGF) and reported that this CGS impregnated with bFGF promoted dermis-like tissue formation. We herein confirmed the single-sustained release of hepatocyte growth factor (HGF) and the dual sustained release of HGF and bFGF from CGSs, and explored its efficacy using a murine model of skin defects. MATERIALS AND METHODS: The sustained release of HGF alone and both HGF and bFGF from CGSs were evaluated in vitro...
January 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29229120/susceptibility-of-eptfe-vascular-grafts-and-bioengineered-human-acellular-vessels-to-infection
#8
Robert D Kirkton, Heather L Prichard, Maribel Santiago-Maysonet, Laura E Niklason, Jeffrey H Lawson, Shannon L M Dahl
BACKGROUND: Synthetic expanded polytetrafluorethylene (ePTFE) grafts are routinely used for vascular repair and reconstruction but prone to sustained bacterial infections. Investigational bioengineered human acellular vessels (HAVs) have shown clinical success and may confer lower susceptibility to infection. Here we directly compared the susceptibility of ePTFE grafts and HAV to bacterial contamination in a preclinical model of infection. MATERIALS AND METHODS: Sections (1 cm2) of ePTFE (n = 42) or HAV (n = 42) were inserted within bilateral subcutaneous pockets on the dorsum of rats and inoculated with Staphylococcus aureus (107 CFU/0...
January 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29228673/inhibition-of-pressure-activated-cancer-cell-adhesion-by-fak-derived-peptides
#9
Bixi Zeng, Dinesh Devadoss, Shouye Wang, Emilie E Vomhof-DeKrey, Leslie A Kuhn, Marc D Basson
Forces within the surgical milieu or circulation activate cancer cell adhesion and potentiate metastasis through signaling requiring FAK-Akt1 interaction. Impeding FAK-Akt1 interaction might inhibit perioperative tumor dissemination, facilitating curative cancer surgery without global FAK or AKT inhibitor toxicity. Serial truncation and structurally designed mutants of FAK identified a seven amino acid, short helical structure within FAK that effectively competes with Akt1-FAK interaction. Adenoviral overexpression of this FAK-derived peptide inhibited pressure-induced FAK phosphorylation and AKT-FAK coimmunoprecipitation in human SW620 colon cancer cells briefly exposed to 15mmHg increased pressure, consistent with laparoscopic or post-surgical pressures...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29228443/postoperative-deep-wound-dehiscence-of-thoracotomy-with-isolation-of-corynebacterium-tuberculostearicum-surgical-site-infection-or-colonization
#10
A Tampakis, E C Tampaki, K Kontzoglou, E Patsouris, G Kouraklis, D Lardinois
OBJECTIVE: Infections with Corynebacterium tuberculostearicum are very rare as in most of the cases its isolation is associated with tissue colonization rather than infection. CASE REPORT: An 80-year old female patient was sent to the consultation hour of thoracic surgery for evaluation of a symptomatic persistent unilateral pleural effusion of her right lung. The differential diagnosis included either the presence of a chronic pleural empyema or the presence of malignancy...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29224829/plasticity-of-oral-mucosal-cell-sheets-for-accelerated-and-scarless-skin-wound-healing
#11
Jong-Lyel Roh, Jaewang Lee, Eun Hye Kim, Daiha Shin
OBJECTIVES: Wound healing is generally faster and associated with less scarring in the oral mucosa than in the skin. Although rarely studied, oral mucosa equivalents may contribute to rapid, scarless cutaneous wound healing. Therefore, we examined the potential utility of our newly developed oral mucosal cell sheet in skin wound healing. MATERIALS AND METHODS: Oral mucosa and skin samples were obtained from surgical patients and Sprague-Dawley rats. Keratinocytes and fibroblasts were primarily cultured for in vitro cell expansion...
December 2017: Oral Oncology
https://www.readbyqxmd.com/read/29224818/reconstruction-after-salvage-laryngectomy
#12
David H Yeh, Axel Sahovaler, Kevin Fung
Both early and advanced stage laryngeal cancers are treated with organ-preserving strategies including radiation alone or concurrent chemoradiotherapy. While organ-preserving modalities have proven effective in eradicating cancer while also preserving laryngeal function, there remains a proportion of cases where residual or recurrent cancer prevails, or conversely, where radiotherapy renders a larynx dysfunctional. In these circumstances, salvage total laryngectomy is often the surgical treatment. The effects of radiotherapy to the neck, amplified by chemotherapy, can create an inhospitable surgical environment, making the salvage laryngectomy an operation fraught with the potential for major complications such as the dreaded pharyngocutaneous fistula...
December 2017: Oral Oncology
https://www.readbyqxmd.com/read/29223734/activation-of-the-epor-%C3%AE-common-receptor-complex-by-cibinetide-ameliorates-impaired-wound-healing-in-mice-with-genetic-diabetes
#13
Alessandra Bitto, Natasha Irrera, Gabriele Pizzino, Giovanni Pallio, Federica Mannino, Mario Vaccaro, Vincenzo Arcoraci, Federica Aliquò, Letteria Minutoli, Michele R Colonna, Maria Rosaria Galeano, Michael Brines, Chiara De Ponte, Massimo Collino, Francesco Squadrito, Domenica Altavilla
Diabetes is characterized by poor wound healing which currently lacks an efficacious treatment. The innate repair receptor (IRR) is a master regulator of tissue protection and repair which is expressed as a response injury or metabolic stress, including in diabetes. Activation of the IRR might provide benefit for diabetic wound healing. A specific IRR agonist cibinetide was administered in an incisional wound healing model performed mice with genetic diabetes (db+/db+) and compared to the normal wild-type. Animals were treated daily with cibinetide (30μg/kg/s...
December 6, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29223650/dry-eye-following-cataract-surgery-the-effect-of-light-exposure-using-an-in-vitro-model
#14
Tugce Ipek, Mariana Petronela Hanga, Andreas Hartwig, James Wolffsohn, Clare O'Donnell
PURPOSE: Cataract surgery can lead to the temporary development or worsening of dry eye symptoms. Contributing factors may include corneal incisions, agents used before, during or after surgery, light from the operating microscope, disruption of ocular surface tissues and inflammatory processes. The purpose of this study was to observe the effect of light exposure on conjunctival fibroblasts in order to determine whether light has an effect on wound healing closure, assuming that operating microscopes might have an effect on the ocular surface...
December 6, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29223423/the-requirement-of-sutures-to-close-intercostal-drains-site-wounds-in-thoracic-surgery
#15
Jeremy L C Smelt, Natalie Simon, Lukacs Veres, Karen Harrison-Phipps, Andrea Bille
BACKGROUND: Chest drains are used routinely in thoracic surgery. Often a pursestring or mattress suture is used to facilitate closure of the defect on removal of the drain. This stitch can cause an unsightly scar, increase drain removal pain, and necessitate that the patient attend a community health care center to have this removed. The objective of this study was to assess whether this stitch is necessary in modern thoracic surgical practice. METHODS: Data from a single surgeon's practice were collected over an 18-month period...
December 6, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29222684/how-much-do-plastic-surgeons-add-to-the-closure-of-myelomeningoceles
#16
Rhian Bevan, Nicholas Wilson-Jones, Imran Bhatti, Chirag Patel, Paul Leach
PURPOSE: This study reviews the outcomes of children undergoing myelomeningocele (MMC) repair in the paediatric neurosurgical department in Cardiff. These procedures are historically performed by paediatric neurosurgeons with occasional support from plastic surgeons for the larger lesions. We reviewed the postoperative outcomes over a 9-year period to assess the efficacy of having a plastic surgeon present at all MMC closures. METHODS: Analysis of a prospectively collected database of all MMC closures performed at University Hospital Wales from April 2009 to August 2017 was used...
December 8, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29219924/combined-laparoscopic-and-perineal-approach-to-omental-interposition-repair-of-complex-rectovaginal-fistula
#17
Hester de Bruijn, Yasuko Maeda, Jamie Murphy, Janindra Warusavitarne, Carolynne J Vaizey
INTRODUCTION: Surgical repair of rectovaginal fistula remains a challenge. Complex and recurrent rectovaginal fistula repairs often fail because of scarring and devascularization of the surrounding tissue. Omental interposition may promote healing by introducing bulky vascularized tissue into the rectovaginal septum. TECHNIQUE: With the patient in the lithotomy position, the rectovaginal septum was dissected transperineally up to the fistula tract and the openings on both vaginal and rectal sides were closed using interrupted, absorbable sutures...
January 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29219215/wound-healing-activity-of-streptocaulon-juventas-root-ethanolic-extract
#18
Can Nguyen Minh, To Le Dinh, Kamei Kaeko, Thao Dang Thi Phuong
Streptocaulon juventas is a well-known plant that has antimicrobial activity, in vitro antiplasmodial activity, anti-proliferative activity, and antioxidant activity. In this study, we showed experimental evidence that proved that Streptocaulon juventas root ethanolic extract has wound healing activities. First, in a mouse excision wound model, Streptocaulon juventas root ethanolic extract at a dose of 100 mg/kg/day significantly reduced the wound closure time. After 7 days, the wound granulation tissue in mice treated with the extract exhibited a 2...
December 8, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/29218673/results-of-endoscopic-vacuum-assisted-closure-device-for-treatment-of-upper-gi-leaks
#19
Marc Bludau, Hans F Fuchs, Till Herbold, Martin K H Maus, Hakan Alakus, Felix Popp, Jessica M Leers, Christiane J Bruns, Arnulf H Hölscher, Wolfgang Schröder, Seung-Hun Chon
BACKGROUND: Esophageal perforations and postoperative leakage of esophagogastrostomies are considered to be life-threatening conditions due to the potential development of mediastinitis and consecutive sepsis. Vacuum-assisted closure (VAC) techniques, a well-established treatment method for superficial infected wounds, are based on a negative pressure applied to the wound via a vacuum-sealed sponge. Endoluminal VAC (E-VAC) therapy as a treatment for GI leakages in the rectum was introduced in 2008...
December 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29218091/angiogenic-and-wound-healing-potency-of-fermented-virgin-coconut-oil-in-vitro-and-in-vivo-studies
#20
Ahmad H Ibrahim, Haibo Li, Sawsan S Al-Rawi, Aman Shah Abdul Majid, Omar Am Al-Habib, Xiaobo Xia, Amin Ms Abdul Majid, Dan Ji
OBJECTIVE: The process of wound healing involves activation of keratinocytes, fibroblasts, endothelial cells, etc. Angiogenesis is crucial during the process of wound healing. Virgin coconut oil is widely utilized in South Asia for various purposes including food, medicinal and industrial applications. This study aimed to evaluate the potency of fermented virgin coconut oil (FVCO) in angiogenesis and wound healing via both in vitro and in vivo assays. METHODS: Human umbilical vein endothelial (HUVEC), fibroblast (CCD-18) and retinal ganglion (RGC-5) cells were cultured in medium containing different concentrations of FVCO...
2017: American Journal of Translational Research
keyword
keyword
54586
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"