keyword
MENU ▼
Read by QxMD icon Read
search

Wound closure

keyword
https://www.readbyqxmd.com/read/28079551/current-techniques-for-burn-reconstruction-using-dehydrated-human-amnion-chorion-membrane-allografts-as-an-adjunctive-treatment-along-the-reconstructive-ladder
#1
Paul M Glat, Thomas Davenport
The reconstructive ladder is a term coined by reconstructive plastic surgeons to describe levels of increasingly complex management of wounds. The first rungs of the ladder is allowing the wound to heal by secondary intention, advancing up the ladder to direct tissue closure, with skin grafting and tissue transfer (flaps) comprising the higher rungs. Skin grafting and tissue transfer (flaps) at the middle and higher rungs of the ladder are often necessary for the treatment of complex burn injuries. Our purpose is to describe how dehydrated human amnion/chorion membrane allografts may be used as an adjunctive treatment...
February 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28078713/the-novel-mtor-complex-1-2-inhibitor-p529-inhibits-human-lung-myofibroblast-differentiation
#2
Keith T Ferguson, Elizabeth E Torr, Ksenija Bernau, Jonathan Leet, Davis Sherris, Nathan Sandbo
Idiopathic pulmonary fibrosis is a progressive and deadly disorder with very few therapeutic options. Palomid 529 (8-(1-hydroxyethyl)-2-methoxy-3-(4-methoxybenzyloxy)-benzo[c]chromen-6-one; P529) is a novel dual inhibitor of mechanistic target of rapamycin complex 1/2 (mTORC1/2). In these studies, we investigated the effect of P529 on TGF-β-dependent signaling and myofibroblast differentiation. TGF-β-induced phosphorylation of the mTORC1 targets, p70 S6 kinase 1 (S6K1) and eukaryotic translation initiation factor 4E binding protein 1 (4E-BP1), were both dose dependently inhibited by P529 in human lung fibroblasts with maximal inhibition occurring between 10-20 µM...
January 11, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28078466/does-stoma-site-specimen-extraction-increase-postoperative-ileostomy-complication-rates
#3
Wanglin Li, Cigdem Benlice, Luca Stocchi, Hermann Kessler, Emre Gorgun, Meagan Costedio
BACKGROUND: Minimizing incisions has the potential to decrease hernia formation and wound complications following laparoscopic surgery. It is currently unknown if using the stoma site for specimen extraction affects outcomes. This study aims to evaluate the impact of stoma site extraction on postoperative complication rates in laparoscopic colorectal surgery. METHODS: After IRB approval, a retrospective comparative review of 738 consecutive patients (405 M) who underwent laparoscopic colorectal surgery with ileostomy between January 2008 and December 2014 was performed...
January 11, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28078463/endoscopic-vacuum-therapy-for-various-defects-of-the-upper-gastrointestinal-tract
#4
Florian Kuehn, Gunnar Loske, Leif Schiffmann, Michael Gock, Ernst Klar
BACKGROUND: Postoperative, iatrogenic or spontaneous upper gastrointestinal defects result in significant morbidity and mortality of the patients. In the last few years, endoscopic vacuum therapy (EVT) has been recognized as a new promising method for repairing upper gastrointestinal defects of different etiology. However, probably due to insufficient data and no commercially available system for EVT of the upper gastrointestinal tract, until the end of 2014, covering of esophageal defects with self-expanding metal stents (SEMS) were still the mainstay of endoscopic therapy...
January 11, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28077304/drosophila-dorsal-closure-an-orchestra-of-forces-to-zip-shut-the-embryo
#5
REVIEW
Peran Hayes, Jérôme Solon
Dorsal closure, a late-embryogenesis process, consists in the sealing of an epidermal gap on the dorsal side of the Drosophila embryo. Because of its similarities with wound healing and neural tube closure in humans, it has been extensively studied in the last twenty years. The process requires the coordination of several force generating mechanisms, that together will zip shut the epidermis. Recent works have provided a precise description of the cellular behavior at the origin of these forces and proposed quantitative models of the process...
January 7, 2017: Mechanisms of Development
https://www.readbyqxmd.com/read/28073875/unexpected-complication-after-radical-inguinal-orchidectomy-trans-sphincteric-anoscrotal-fistula
#6
Amit Patel, Chris Gillespie, Anthony J Kiosoglous
Anoscrotal fistula is an extremely rare condition involving an epithelialised tract between the anal canal and scrotal wall. It is more commonly seen as a congenital phenomenon in the paediatric population, and has not previously been described in the literature in adults. We present the case of a man aged 52 years who developed a complex anoscrotal fistula after a radical inguinal orchidectomy for an intratesticular seminoma. A postsurgical wound-site infection developed into a chronically discharging wound refractory to antibiotic treatment prompting further investigation...
January 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28061359/resorbable-suture-as-wound-drain
#7
Eric Dierks, Gerald Harper
The placement of a resorbable suture on one edge of a wound can effectively retard the mucosal closure of the defect and thereby duplicate the function of a passive surgical drain. The placement of a double or triple loop of a resorbable suture such as chromic gut on one side of the wound edge can provide an inexpensive and self-eliminating wound drain.
December 18, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28060880/accelerated-wound-closure-differently-organized-nanofibers-affect-cell-migration-and-hence-the-closure-of-artificial-wounds-in-a-cell-based-in-vitro-model
#8
Maximilian Ottosson, Albin Jakobsson, Fredrik Johansson
Nanofiber meshes holds great promise in wound healing applications by mimicking the topography of extracellular matrix, hence providing guidance for crucial cells involved in the regenerative processes. Here we explored the influence of nanofiber alignment on fibroblast behavior in a novel in vitro wound model. The model included electrospun poly-ε-caprolactone scaffolds with different nanofiber orientation. Fibroblasts were cultured to confluency for 24h before custom-made inserts were removed, creating cell-free zones serving as artificial wounds...
2017: PloS One
https://www.readbyqxmd.com/read/28058229/systematic-review-of-the-negative-pressure-wound-therapy-in-kidney-transplant-recipients
#9
Badri Man Shrestha
AIM: To review negative pressure wound therapy (NPWT) as an important addition to the conventional methods of wound management. METHODS: A systematic review, performed by searching the PubMed, EMBASE and Cochrane Library databases, showed 11 case reports comprising a total of 22 kidney transplantation (KT) patients (range, 1 to 9), who were treated with NPWT. Application of NPWT was associated with successful healing of wounds, leg ulcer, lymphocele and urine leak from ileal conduit...
December 24, 2016: World Journal of Transplantation
https://www.readbyqxmd.com/read/28054925/the-wound-trend-scale-a-retrospective-review-of-utility-and-predictive-value-in-the-assessment-and-documentation-of-lower-leg-ulcers
#10
Noreen A Campbell, Donna L Campbell, Andrea Turner
Wound assessment is essential to manage wound care. The Wound Trend Scale (WTS) is a paper-and-pen instrument comprised of 14 parameters designed to guide assessment of findings relevant to lower leg ulcer management and includes an infection screen and cues for physician consultation. To determine its clinical utility, predictive value, and reliability, data were retrospectively analyzed from a random sampling of medical records of patients seen at a Foot and Leg Clinic between January 1, 2007 and December 31, 2008...
December 2016: Ostomy/wound Management
https://www.readbyqxmd.com/read/28052404/perineal-reconstruction-with-multiple-perforator-flaps-based-on-anatomical-divisions
#11
Joon P Hong, Chang G Kim, Hyun S Suh, Hoon Kim, Chi S Yoon, Kyu N Kim
PURPOSE: Reconstruction of perineal defects remains a challenge because such defects can be extensive, complex, and three-dimensional. This report presents a retrospective review of our past 5 years of experience in perineal reconstruction, and suggests a simple algorithmic approach according to anatomical divisions with multiple pedicled perforator flaps for extensive perineal defects. METHODS: From January 2011 to December 2015, 16 patients, including 5 men and 11 women, underwent reconstruction of extensive perineal defects...
January 4, 2017: Microsurgery
https://www.readbyqxmd.com/read/28051048/outcome-of-primary-closure-of-abdominal-wounds-following-laparotomy-for-peritonitis-in-children
#12
Stephen Akau Kache, Philip M Mshelbwala, Emmanuel A Ameh
BACKGROUND: Primary wound closure following laparotomy for peritonitis is generally believed to be associated with wound complications and long hospital stay. Open wound management has long been the most common practice after laparotomy for peritonitis. Primary closure (PC), however, has recently been advocated to reduce cost and morbidity. This study determined the incidence and severity of wound complications and their impact on hospital stay and overall outcome when PC of abdominal wounds is done following laparotomy for peritonitis...
October 2016: African Journal of Paediatric Surgery: AJPS
https://www.readbyqxmd.com/read/28050534/the-use-of-negative-pressure-wound-therapy-in-the-treatment-of-infected-wounds-case-studies
#13
Daniel de Alcântara Jones, Wilson Vasconcelos Neves Filho, Janice de Souza Guimarães, Daniel de Araújo Castro, Antonio Marcos Ferracini
OBJECTIVE: To evaluate the results and benefits obtained from the topical use of negative pressure wound therapy (NPWT) in patients with infected wounds. METHODS: This was a retrospective study of 20 patients (17 males and three females, mean age 42 years) with infected wounds treated using NPWT. The infected wounds were caused by trauma. The treatment system used was VAC.(®) (Vacuum Assisted Closure, KCI, San Antonio, United States) applied to the wound in continuous mode from 100 to 125 mmHg...
November 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28050439/rotation-flap-closure-of-moderate-size-scalp-defects-technique-and-outcome
#14
Philip Umman, Vinod G Pillai, Pradip M Abraham, Roshan G Varkey
Many patients present to general surgeons with scalp lesions which require wide local excision with margin, following which the defect is too large to be closed primarily. These lesions can be benign or malignant. Skin grafting of these defects gives poor cosmetic outcome. Knowledge of basic flaps will enable the general surgeon to close these defects to heal by primary intention. Also, the margin of excision will not be compromised because of anticipated difficulty in closing the wound. We present a series of three cases who underwent excision of scalp lesions resulting in moderate size scalp defects...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28050314/biocompatibility-study-of-lithium-disilicate-and-zirconium-oxide-ceramics-for-esthetic-dental-abutments
#15
Céline Brunot-Gohin, Jean-Luc Duval, Sandra Verbeke, Kayla Belanger, Isabelle Pezron, Gérard Kugel, Dominique Laurent-Maquin, Sophie Gangloff, Christophe Egles
PURPOSE: The increasing demand for esthetically pleasing results has contributed to the use of ceramics for dental implant abutments. The aim of this study was to compare the biological response of epithelial tissue cultivated on lithium disilicate (LS2) and zirconium oxide (ZrO2) ceramics. Understanding the relevant physicochemical and mechanical properties of these ceramics will help identify the optimal material for facilitating gingival wound closure. METHODS: Both biomaterials were prepared with 2 different surface treatments: raw and polished...
December 2016: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/28047677/su-f-p-59-detection-of-missing-surgical-needles-with-intraoperative-mobile-x-ray
#16
L Chen, B Berger
PURPOSE: To determine the minimal detectable size of a surgical needle using intraoperative mobile x-ray imaging. Also, varying techniques such as low kVp and high tube current were tested to investigate whether this improved the detection of the various needle sizes. METHODS: Seven surgical needle sizes, 6.5, 8, 11, 13, 16, 17 and 19 mm, were positioned on three regions (thoracic, abdominal and pelvic) of an adult size anthropomorphic RANDO phantom. The phantom represents an average size adult...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043766/re-operative-urethroplasty-after-failed-hypospadias-repair-how-prior-surgery-impacts-risk-for-additional-complications
#17
W Snodgrass, N C Bush
PURPOSE: The primary aim of this report was to compare urethroplasty complications for primary distal and proximal repairs with those after 1, 2, 3, and 4 or more re-operations. METHODS: Prospectively collected data on consecutive hypospadias repairs (tubularized incised plate (TIP), inlay, two-stage graft) from 2000 to 2015 were reviewed. Isolated fistula closures were excluded. Extracted information included patient age, meatal location, repair type, primary vs...
December 7, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28040363/wound-healing-promoting-effect-of-total-tannins-from-entada-phaseoloides-l-merr-in-rats
#18
Xiaowen Su, Xinguang Liu, Shouyu Wang, Bin Li, Taowen Pan, Dingrui Liu, Fei Wang, Yunpeng Diao, Kun Li
The healing of wounds has always provided challenges for the medical community whether chronic or acute. Modern and traditional medicine has proved that herbal medicine shown superiority over chemical drugs. Herein, we report an Entada phaseoloides (L.) Merr. extract with a total tannin content of 76.18% showed wound-healing promoting effect in rat model. We found significantly accelerated wound closure already on day 7 in animals treated with total Entada phaseoloides (L.) Merr. tannins (TEPT) as compared to vaseline treated controls (p<0...
December 28, 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28040255/does-prophylactic-mesh-placement-in-elective-midline-laparotomy-reduce-the-incidence-of-incisional-hernia-a-systematic-review-and-meta-analysis
#19
Zachary M Borab, Sameer Shakir, Michael A Lanni, Michael G Tecce, John MacDonald, William W Hope, John P Fischer
BACKGROUND: Operative intervention to correct incisional hernia affects 150,000 patients annually, with 1 in 3 repairs recurring within 9 years. The aim of this study was to compare the incidence of incisional hernia and postoperative complications in elective midline laparotomy patients after the use of prophylactic mesh placement and primary suture closure. METHODS: A systematic review was performed to identify studies comparing prophylactic mesh placement to primary suture closure in elective, midline laparotomy at index abdominal aponeurosis closure...
December 28, 2016: Surgery
https://www.readbyqxmd.com/read/28035413/tim-3-is-upregulated-in-human-colorectal-carcinoma-and-associated-with-tumor-progression
#20
Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Peng Zhang
T cell immunoglobulin mucin-3 (Tim-3) has previously been implicated in the immune response and tumor biology. Colorectal carcinoma (CRC) is a malignancy, which is closely associated with inflammation. However, the role of Tim‑3 in the progression of CRC remains to be fully elucidated. The present study aimed to investigate the role of Tim‑3 in the progressive activities of human CRC. A total of 30 clinical CRC tissues and their adjacent tissues were collected. Slides from another 112 cases that underwent CRC surgical resection were also obtained...
December 22, 2016: Molecular Medicine Reports
keyword
keyword
54586
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"