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https://www.readbyqxmd.com/read/29779827/zika-virus-report-from-the-task-force-on-tropical-diseases-by-the-world-federation-of-societies-of-intensive-and-critical-care-medicine
#1
Gisele Sampaio Silva, Guy A Richards, Tim Baker, Jorge Hidalgo, Juan Ignacio Silesky Jiménez, Pravin Amin
Zika fever is an acute infectious disease caused by the Zika virus (ZIKV), an RNA virus belonging to the genus Flavivirus. ZIKV can be transmitted by bites from Aedes aegypti and Aedes albopictus species, sexual activity, blood transfusion and from mother to fetus during pregnancy and delivery. A total of 50 territories and countries in the Americas had reported ZIKV infections. For those with symptoms, the presentation is similar to dengue fever with body aches, joint pain, fatigue, malaise, fever and conjunctivitis lasting up to seven days...
April 5, 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/29773562/neuroimaging-findings-of-zika-virus-associated-neurologic-complications-in-adults
#2
REVIEW
L C Hygino da Cruz, O J M Nascimento, F P P L Lopes, I R F da Silva
When the first suspected cases of neurologic disorders associated with the Zika virus were noticed in Brazil in late 2015, several studies had been conducted to understand the pathophysiology of the disease and its associated complications. In addition to its well-established association with microcephaly in neonates, the Zika virus infection has also been suggested to trigger other severe neurologic complications in adults, such as Guillain-Barré syndrome, radiculomyelitis, and meningoencephalitis. Hence, the Zika virus should be deemed a global threat that can cause devastating neurologic complications among individuals in all age ranges...
May 17, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29760923/finger-drop-sign-characteristic-pattern-of-distal-weakness-in-guillain-barr%C3%A3-syndrome-a-case-report-and-review-of-the-literature
#3
Yong Chuan Chee, Beng Hooi Ong
Guillain-Barré Syndrome is an acquired acute autoimmune polyradiculoneuropathy that commonly presents with limb weakness and occasional cranial nerve, respiratory and autonomic involvement. Although the classic description of Guillain-Barré Syndrome is that of a demyelinating neuropathy with ascending weakness, predominant bilateral finger drop as presenting feature has rarely been reported. A characteristic pattern of weakness involving the extensor components of the fingers known as "finger drop sign" has been first described to be specific in acute motor axonal neuropathy form of Guillain-Barré Syndrome in the literature...
2018: SAGE open medical case reports
https://www.readbyqxmd.com/read/29759074/dengue-fever-complicated-with-guillain-barr%C3%A3-syndrome-a-case-report-and-review-of-the-literature
#4
Chamara Dalugama, John Shelton, Mahendra Ekanayake, Indika Bandara Gawarammana
BACKGROUND: Dengue is an arboviral infection classically presenting with fever, arthralgia, headache, and rashes. It is hyperendemic in Sri Lanka and has a major impact on health. Neurological complications of dengue fever are rare but have been reported in the literature. CASE PRESENTATION: A 60-year-old Sri Lankan man presented with a history of fever, arthralgia, and generalized malaise of 2 days duration. A diagnosis of dengue was confirmed with leukopenia, thrombocytopenia, and positive NS1 antigen done on day 2 without evidence of hemoconcentration...
May 15, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29758005/a-review-of-the-ongoing-research-on-zika-virus-treatment
#5
REVIEW
Suely da Silva, Daniel Oliveira Silva Martins, Ana Carolina Gomes Jardim
The Zika fever is an arboviral disease resulting from the infection with Zika virus (ZIKV). The virus is transmitted to humans by the bite of Aedes mosquitos, mainly Aedes aegypti and Aedes albopictus . ZIKV has been detected for decades in African and Asian regions and, since 2007, has spread to other continents; among them, infections are most reported in the Americas. This can be explained by the presence of vectors in highly populated and tropical regions where people are susceptible to contamination. ZIKV has been considered by the World Health Organization a serious public health problem because of the increasing number of cases of congenital malformation and neurological disorders related to its infection, such as microcephaly, Guillain⁻Barré syndrome, meningoencephalitis, and myelitis...
May 14, 2018: Viruses
https://www.readbyqxmd.com/read/29747820/gangliosides-and-autoimmune-peripheral-nerve-diseases
#6
John A Goodfellow, Hugh J Willison
A wide range of neuroimmunological diseases, referred to as autoimmune neuropathies, affect the peripheral nervous systems (PNS). The PNS is structurally diverse with complex anatomical compartments enriched in many different myelin and neuronal glycolipids, notably gangliosides. Autoimmune neuropathies are a proportion of autoimmune neuropathies mediated by autoimmune attack due to antibodies reactive with these compartmentally localized gangliosides. Antiganglioside antibodies are principally associated with the acute paralytic disease, Guillain-Barré syndrome, and are also found in several chronic autoimmune neuropathy syndromes...
2018: Progress in Molecular Biology and Translational Science
https://www.readbyqxmd.com/read/29740383/nervous-system-injury-and-neuroimaging-of-zika-virus-infection
#7
REVIEW
Shanshan Wu, Yu Zeng, Alexander Lerner, Bo Gao, Meng Law
In 2016, World Health Organization announced Zika virus infection and its neurological sequalae are a public health emergency of global scope. Preliminary studies have confirmed a relationship between Zika virus infection and certain neurological disorders, including microcephaly and Guillain-Barre syndrome (GBS). The neuroimaging features of microcephaly secondary to Zika virus infection include calcifications at the junction of gray-white matter and subcortical white matter with associated cortical abnormalities, diminution of white matter, large ventricles with or without hydrocephalus, cortical malformations, hypoplasia of cerebellum and brainstem, and enlargement of cerebellomedullary cistern...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29698814/ocular-abnormalities-in-congenital-zika-syndrome-are-the-ophthalmoscopic-findings-the-top-of-the-iceberg
#8
REVIEW
João Rafael de Oliveira Dias, Camila V Ventura, Bruno de Paula Freitas, Juliana Prazeres, Liana O Ventura, Vasco Bravo-Filho, Tomas Aleman, Albert Icksang Ko, Andréa Zin, Rubens Belfort, Mauricio Maia
Zika virus (ZIKV) is an arbovirus mainly transmitted to humans by mosquitoes from Aedes genus. Other ways of transmission include the perinatal and sexual routes, blood transfusion, and laboratory exposure. Although the first human cases were registered in 1952 in African countries, outbreaks were only reported since 2007, when entire Pacific islands were affected. In March 2015, the first cases of ZIKV acute infection were notified in Brazil and, to date, 48 countries and territories in the Americas have confirmed local mosquito-borne transmission of ZIKV...
April 23, 2018: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/29695953/autoimmune-neurological-conditions-associated-with-zika-virus-infection
#9
REVIEW
Yeny Acosta-Ampudia, Diana M Monsalve, Luis F Castillo-Medina, Yhojan Rodríguez, Yovana Pacheco, Susan Halstead, Hugh J Willison, Juan-Manuel Anaya, Carolina Ramírez-Santana
Zika virus (ZIKV) is an emerging flavivirus rapidly spreading throughout the tropical Americas. Aedes mosquitoes is the principal way of transmission of the virus to humans. ZIKV can be spread by transplacental, perinatal, and body fluids. ZIKV infection is often asymptomatic and those with symptoms present minor illness after 3 to 12 days of incubation, characterized by a mild and self-limiting disease with low-grade fever, conjunctivitis, widespread pruritic maculopapular rash, arthralgia and myalgia. ZIKV has been linked to a number of central and peripheral nervous system injuries such as Guillain-Barré syndrome (GBS), transverse myelitis (TM), meningoencephalitis, ophthalmological manifestations, and other neurological complications...
2018: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29681203/the-immunotherapy-of-guillain-barr%C3%A3-syndrome
#10
Paula Restrepo-Jiménez, Yhojan Rodríguez, Paulina González, Christopher Chang, M Eric Gershwin, Juan-Manuel Anaya
Guillain-Barré syndrome is the most common cause of acute flaccid paralysis worldwide. Microorganisms such as Campylobacter jejuni, Cytomegalovirus, Epstein-Barr virus, Mycoplasma pneumoniae, Haemophilus influenzae and Zika virus have been linked to the disease. The most common clinical variants are acute inflammatory demyelinating polyneuropathy and acute motor axonal neuropathy. Plasma exchange and intravenous immunoglobulins are the standard therapy for the disease. Areas covered: research to elucidate the pathophysiology of Guillain-Barré syndrome has led to the development of drugs directed towards new potential therapeutic targets...
May 8, 2018: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/29671175/characterisation-of-bone-and-joint-infections-due-to-group-b-streptococcus-serotype-iii-sequence-type-283
#11
Sean W Ong, Timothy Barkham, Win Mar Kyaw, Hanley J Ho, Monica Chan
In 2015, an epidemic of Group B Streptococcus (GBS) serotype III sequence type 283 (ST283) disease was reported in Singapore, associated with consumption of raw freshwater fish. In this study, we further characterise the characteristics of bone and joint infections associated with ST283 GBS in adults and the differences between ST283 and non-ST283 manifestations. A retrospective study of 54 inpatients with invasive GBS disease involving bones and/or joints from 2010 to 2015 was performed. Archived isolates were identified as GBS serotype III and ST283 positive using PCR methods...
April 18, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29669602/cerebral-vasculitis-and-lateral-rectus-palsy-two-rare-central-nervous-system-complications-of-dengue-fever-two-case-reports-and-review-of-the-literature
#12
H M M Herath, J S Hewavithana, C M De Silva, O A R Kularathna, N P Weerasinghe
BACKGROUND: Dengue fever is a common mosquito-borne viral illness with a clinical spectrum ranging from a simple febrile illness to potentially life-threatening complications such as dengue hemorrhagic fever and dengue shock syndrome. Dengue infection can affect many organs, including the central nervous system. The neurological manifestations reported in dengue infections are meningitis, encephalitis, stroke, acute disseminated encephalomyelitis, and Guillain-Barré syndrome. CASE PRESENTATION: We report the cases of two interesting patients with confirmed dengue infection who presented with complications of possible central nervous system vasculitis and cranial nerve palsy...
April 19, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29668332/neurological-complications-of-zika-virus-infection
#13
Francisco Javier Carod-Artal
Zika virus (ZIKV) disease is a vector-borne infectious disease transmitted by Aedes mosquitoes. Recently, ZIKV has caused outbreaks in most American countries. Areas covered: Publications about neurological complications of ZIKV infection retrieved from pubmed searchers were reviewed, and reference lists and relevant articles from review articles were also examined. Vertical/intrauterine transmission leads to congenital infection and causes microcephaly and congenital ZIKV syndrome. ZIKV preferentially infects human neural progenitor cells and triggers cell apoptosis...
May 2018: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/29665882/effects-of-antibiotic-resistance-ar-and-microbiota-shifts-on-campylobacter-jejuni-mediated-diseases
#14
Phillip T Brooks, Linda S Mansfield
Campylobacter jejuni is an important zoonotic pathogen recently designated a serious antimicrobial resistant (AR) threat. While most patients with C. jejuni experience hemorrhagic colitis, serious autoimmune conditions can follow including inflammatory bowel disease (IBD) and the acute neuropathy Guillain Barré Syndrome (GBS). This review examines inter-relationships among factors mediating C. jejuni diarrheal versus autoimmune disease especially AR C. jejuni and microbiome shifts. Because both susceptible and AR C...
December 2017: Animal Health Research Reviews
https://www.readbyqxmd.com/read/29665426/human-papillomavirus-vaccine-and-demyelinating-diseases-a-systematic-review-and-meta-analysis
#15
Julie Mouchet, Francesco Salvo, Emanuel Raschi, Elisabetta Poluzzi, Ippazio Cosimo Antonazzo, Fabrizio De Ponti, Bernard Bégaud
Approved in 2006, human papillomavirus (HPV) vaccines were initially targeted for girls aged 9-14 years. Although the safety of these vaccines has been monitored through post-licensure surveillance programmes, cases of neurological events have been reported worldwide. The present study aimed to assess the risk of developing demyelination after HPV immunization by meta-analysing risk estimates from pharmacoepidemiologic studies. A systematic review was conducted in Medline, Embase, ISI Web of Science and the Cochrane Library from inception to 10 May 2017, without language restriction...
April 14, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29663680/knowledge-gaps-in-control-of-campylobacter-for-prevention-of-campylobacteriosis
#16
I Hansson, M Sandberg, I Habib, R Lowman, E O Engvall
Campylobacteriosis is an important, worldwide public health problem with numerous socio-economic impacts. Since 2015, approximately 230,000 cases have been reported annually in Europe. In the United States, Australia and New Zealand, campylobacteriosis is the most commonly reported disease. Poultry and poultry products are considered important sources of human infections. Poultry meat can become contaminated with Campylobacter during slaughter if live chickens are intestinal carriers. Campylobacter spp. can be transferred from animals to humans through consumption and handling of contaminated food products, with fresh chicken meat being the most commonly implicated food type...
April 16, 2018: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29623514/pollution-indices-as-useful-tools-for-the-comprehensive-evaluation-of-the-degree-of-soil-contamination-a-review
#17
REVIEW
Joanna Beata Kowalska, Ryszard Mazurek, Michał Gąsiorek, Tomasz Zaleski
The paper provides a complex, critical assessment of heavy metal soil pollution using different indices. Pollution indices are widely considered a useful tool for the comprehensive evaluation of the degree of contamination. Moreover, they can have a great importance in the assessment of soil quality and the prediction of future ecosystem sustainability, especially in the case of farmlands. Eighteen indices previously described by several authors (Igeo , PI, EF, Cf , PIsum , PINemerow , PLI, PIave , PIVector , PIN, MEC, CSI, MERMQ, Cdeg , RI, mCd and ExF) as well as the newly published Biogeochemical Index (BGI) were compared...
April 5, 2018: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/29613895/infectious-myelopathies
#18
Marie F Grill
PURPOSE OF REVIEW: This article reviews bacterial, viral, fungal, and parasitic pathogens associated with myelopathy. Infectious myelopathies may be due to direct infection or parainfectious autoimmune-mediated mechanisms; this article focuses primarily on the former. RECENT FINDINGS: Some microorganisms exhibit neurotropism for the spinal cord (eg, enteroviruses such as poliovirus and flaviviruses such as West Nile virus), while others are more protean in neurologic manifestations (eg, herpesviruses such as varicella-zoster virus), and others are only rarely reported to cause myelopathy (eg, certain fungal and parasitic infections)...
April 2018: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29601454/bacterial-load-and-molecular-markers-associated-with-early-onset-group-b-streptococcus-a-systematic-review-and-meta-analysis
#19
Farah Seedat, Colin Stewart Brown, Chris Stinton, Jacoby Patterson, Julia Geppert, Karoline Freeman, Bee Tan, Samantha Ann Johnson, Hannah Fraser, Olalekan A Uthman, Esther R Robinson, Noel Denis McCarthy, Aileen Clarke, Sian Taylor-Phillips
BACKGROUND: The natural history of neonatal group B Streptococcus (GBS) is poorly understood. Little is known about the bacterial factors influencing the transmission of GBS from mother to neonate, or the development of invasive early-onset GBS disease (EOGBS) in colonized neonates. We reviewed whether bacterial load and molecular markers are associated with GBS vertical transmission and progression to EOGBS. METHODS: We searched Medline, Embase, Cochrane and Web of Science from inception to 10 October 2016 for observational studies in English...
March 27, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29593684/group-b-streptococcal-colonization-molecular-characteristics-and-epidemiology
#20
REVIEW
Sarah Shabayek, Barbara Spellerberg
Streptococcus agalactiae or group B streptococcus (GBS) is a leading cause of serious neonatal infections. GBS is an opportunistic commensal constituting a part of the intestinal and vaginal physiologic flora and maternal colonization is the principal route of GBS transmission. GBS is a pathobiont that converts from the asymptomatic mucosal carriage state to a major bacterial pathogen causing severe invasive infections. At present, as many as 10 serotypes (Ia, Ib, and II-IX) are recognized. The aim of the current review is to shed new light on the latest epidemiological data and clonal distribution of GBS in addition to discussing the most important colonization determinants at a molecular level...
2018: Frontiers in Microbiology
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