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https://www.readbyqxmd.com/read/29677654/diagnosis-of-lumbar-spinal-fractures-in-emergency-department-low-dose-versus-standard-dose-ct-using-model-based-iterative-reconstruction
#1
Sun Hwa Lee, Seong Jong Yun, Hyeon Hwan Jo, Jae Gwang Song
PURPOSE: To compared the diagnostic performance of low-dose (LD) lumbar-spine (L-spine) CT with that of standard-dose (SD) L-spine CT. METHODS: Patients who underwent SD (n = 76) or LD (n = 68) L-spine CT using model-based iterative reconstruction were included. Two reviewers independently analyzed 10 anatomical regions on both CT scans. Also, suggested treatment decision between both CT scans was compared. RESULTS: LD L-spine CT showed an excellent diagnostic accuracy (98...
April 14, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29677606/5-hz-repetitive-transcranial-magnetic-stimulation-for-posttraumatic-stress-disorder-comorbid-with-major-depressive-disorder
#2
Linda L Carpenter, Christine Conelea, Audrey R Tyrka, Emma S Welch, Benjamin D Greenberg, Lawrence H Price, Matthew Niedzwiecki, Agustin G Yip, Jennifer Barnes, Noah S Philip
BACKGROUND: Standard clinical protocols for repetitive transcranial magnetic stimulation (rTMS) for major depressive disorder (MDD) apply 10 Hz pulses over left prefrontal cortex, yet little is known about the effects of rTMS in more diagnostically complex depressed patients. OBJECTIVE/HYPOTHESIS: Posttraumatic stress disorder (PTSD) is commonly comorbid with MDD, and while rTMS has been shown to alleviate PTSD symptoms in preliminary studies, ideal parameters remain unclear...
April 5, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29677408/use-of-oxygen-at-the-end-of-life-attitudes-beliefs-and-practices-in-wisconsin
#3
Lisa Quinn-Lee, Jeanne Weggel, Susan D Moch
INTRODUCTION: Oxygen therapy for the management of breathlessness remains controversial and little information is available regarding the practice of using oxygen at end of life. Oxygen use in end-of-life care is increasingly being questioned, while the use of oxygen for routine "comfort care" at end of life continues. OBJECTIVE: The purpose of this study was to investigate the use of oxygen at the end of life and to understand its role in contemporary palliative care practice...
March 2018: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29677217/optimisation-of-three-dimensional-lower-jaw-resection-margin-planning-using-a-novel-black-bone-magnetic-resonance-imaging-protocol
#4
Astrid M Hoving, Joep Kraeima, Rutger H Schepers, Hildebrand Dijkstra, Jan Hendrik Potze, Bart Dorgelo, Max J H Witjes
BACKGROUND: MRI is the optimal method for sensitive detection of tumour tissue and pre-operative staging in oral cancer. When jawbone resections are necessary, the current standard of care for oral tumour surgery in our hospital is 3D virtual planning from CT data. 3D printed jawbone cutting guides are designed from the CT data. The tumour margins are difficult to visualise on CT, whereas they are clearly visible on MRI scans. The aim of this study was to change the conventional CT-based workflow by developing a method for 3D MRI-based lower jaw models...
2018: PloS One
https://www.readbyqxmd.com/read/29677199/implications-of-current-therapeutic-restrictions-for-primaquine-and-tafenoquine-in-the-radical-cure-of-vivax-malaria
#5
James Watson, Walter R J Taylor, Germana Bancone, Cindy S Chu, Podjanee Jittamala, Nicholas J White
BACKGROUND: The 8-aminoquinoline antimalarials, the only drugs which prevent relapse of vivax and ovale malaria (radical cure), cause dose-dependent oxidant haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Patients with <30% and <70% of normal G6PD activity are not given standard regimens of primaquine and tafenoquine, respectively. Both drugs are currently considered contraindicated in pregnant and lactating women. METHODS: Quantitative G6PD enzyme activity data from 5198 individuals were used to estimate the proportions of heterozygous females who would be ineligible for treatment at the 30% and 70% activity thresholds, and the relationship with the severity of the deficiency...
April 20, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29677126/patient-education-on-oral-anticoagulation
#6
Emily M Hawes
Given the potential harm associated with anticoagulant use, patient education is often provided as a standard of care and emphasized across healthcare settings. Effective anticoagulation education involves face-to-face interaction with a trained professional who ensures that the patient understands the risks involved, the precautions that should be taken, and the need for regular monitoring. The teaching should be tailored to each patient, accompanied with written resources and utilize the teach-back method...
April 20, 2018: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29677085/surgical-antimicrobial-prophylaxis-among-pediatric-patients-in-south-africa-comparing-two-healthcare-settings
#7
Nicolene van der Sandt, Natalie Schellack, Lindi A Mabope, Mothahadini Pb Mawela, Danie Kruger, Brian Godman
BACKGROUND: Appropriate use of surgical antimicrobial prophylaxis (SAP) is a concern in view of its impact on morbidity, mortality and costs. Little is currently known about SAP in South Africa. OBJECTIVE: Assess compliance to SAP guidelines for pediatric patients undergoing surgery in one of four surgical sub-specialties among hospitals in South Africa. METHODS: Eight month retrospective chart review in both a teaching hospital and a private hospital between February and August 2015...
April 19, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29677062/opioid-oversupply-after-joint-and-spine-surgery-a-prospective-cohort-study
#8
Mark C Bicket, Elizabeth White, Peter J Pronovost, Christopher L Wu, Myron Yaster, G Caleb Alexander
BACKGROUND: Many patients receive prescription opioids at hospital discharge after surgery, yet little is known regarding how often these opioids go unused. We estimated the prevalence of unused opioids, use of nonopioid analgesics, and storage and disposal practices after same-day and inpatient surgery. METHODS: In this prospective cohort study at a large, inner-city tertiary care hospital, we recruited individuals ≥18 years of age undergoing elective same-day or inpatient joint and spine surgery from August to November 2016...
April 17, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29677053/safety-profile-of-baroreflex-activation-therapy-neo-in-patients-with-resistant-hypertension
#9
Manuel Wallbach, Enrico Böhning, Luca-Yves Lehnig, Charlotte Schroer, Gerhard Anton Müller, Rolf Wachter, Stephan Lüders, Dieter Zenker, Michael Johann Koziolek
OBJECTIVE: Unlike safety data of baroreflex activation therapy device (Rheos), only few data of the currently used second device (Barostim neo) are available and little is reported about common side effects. METHODS: We prospectively analyzed patients with resistant hypertension treated with Barostim neo. A standardized interview regarding side effects of the therapy was performed in routine follow-up visits after device implantation in 42 patients to determine adverse events staged into three degrees...
April 19, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29677048/criteria-for-diagnosing-primary-aldosteronism-on-the-basis-of-liquid-chromatography-tandem-mass-spectrometry-determinations-of-plasma-aldosterone-concentration
#10
Stephanie Baron, Laurence Amar, Anne-Laure Faucon, Anne Blanchard, Laurence Baffalie, Catherine Faucard, Simon Travers, Jean-Yves Pagny, Michel Azizi, Pascal Houillier
BACKGROUND: Primary aldosteronism is affecting about 10% of hypertensive patients. Primary aldosteronism should be diagnosed by screening tests based on plasma aldosterone concentration (PAC) and aldosterone-to-renin ratio (ARR), followed by confirmatory test. The cutoff values for PAC and ARR depend on PAC and plasma renin measurement methods. Liquid chromatography-tandem mass spectrometry (LC-MS/MS), the new gold standard method for aldosterone determination, is now widespread but shows lower values than immunoassays...
April 19, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29677044/practice-makes-perfect-integrating-technology-to-teach-language-barrier-solutions
#11
Brenda Pavill
This article highlights how academia and industry leaders in health care communication can partner to provide students practice caring for individuals who are limited English proficient and how such practice opportunities can be integrated into academic programs. Highlighted are key elements to consider when partnering with industry leaders to develop a program for students. A course exemplar provides a comprehensive description of a practice exercise integrated in a nursing physical assessment course. Students obtain hands-on experiences caring for limited English proficient standardized patients using state-of-the-art digital video interpreting technology...
April 19, 2018: Nursing Education Perspectives
https://www.readbyqxmd.com/read/29677037/small-left-ventricular-size-is-an-independent-risk-factor-for-ventricular-assist-device-thrombosis
#12
Venkat Keshav Chivukula, Jennifer A Beckman, Anthony R Prisco, Shin Lin, Todd F Dardas, Richard K Cheng, Stephen D Farris, Jason W Smith, Nahush A Mokadam, Claudius Mahr, Alberto Aliseda
The prevalence of ventricular assist device (VAD) therapy has continued to increase due to a stagnant donor supply and growing advanced heart failure (HF) population. We hypothesize that left ventricular (LV) size strongly influences biocompatibility and risk of thrombosis. Unsteady computational fluid dynamics (CFD) was used in conjunction with patient-derived computational modeling and virtual surgery with a standard, apically implanted inflow cannula. A dual-focus approach of evaluating thrombogenicity was employed: platelet-based metrics to characterize the platelet environment and flow-based metrics to investigate hemodynamics...
April 18, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29677035/outflow-cannula-systolic-slope-in-patients-with-left-ventricular-assist-devices-a-novel-marker-of-myocardial-contractility
#13
Jonathan Grinstein, Eric Kruse, Gabriel Sayer, Gene H Kim, Jayant Raikhelkar, Sara Kalantari, Nitasha Sarswat, Sirtaz Adatya, Takeyoshi Ota, Valluvan Jeevanandam, Victor Mor-Avi, Roberto M Lang, Nir Uriel
Left ventricular (LV) unloading with a LV assist device (LVAD) reverse remodels the heart and may lead to favorable changes in cellular architecture and LV geometry promoting myocardial recovery. Currently, there are no standardized methods for evaluating myocardial recovery. This study assesses the systolic slope of the LVAD outflow cannula as a marker for myocardial contractility. Doppler echocardiography (transthoracic echocardiogram [TTE]) of the LVAD outflow cannula and TTE of the LV cavity were prospectively collected in 57 patients with LVADs...
April 18, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29676947/intravenous-chemotherapy-compounding-errors-in-a-follow-up-pan-canadian-observational-study
#14
Rachel E Gilbert, Melissa C Kozak, Roxanne B Dobish, Venetia C Bourrier, Paul M Koke, Vishal Kukreti, Heather A Logan, Anthony C Easty, Patricia L Trbovich
PURPOSE: Intravenous (IV) compounding safety has garnered recent attention as a result of high-profile incidents, awareness efforts from the safety community, and increasingly stringent practice standards. New research with more-sensitive error detection techniques continues to reinforce that error rates with manual IV compounding are unacceptably high. In 2014, our team published an observational study that described three types of previously unrecognized and potentially catastrophic latent chemotherapy preparation errors in Canadian oncology pharmacies that would otherwise be undetectable...
April 20, 2018: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29676933/integration-of-pulmonary-function-data-into-electronic-health-records-time-for-action
#15
M Bradley Drummond, Meredith C McCormack
No abstract text is available yet for this article.
April 20, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29676824/the-safety-effectiveness-and-cost-effectiveness-of-cytisine-in-achieving-six-month-continuous-smoking-abstinence-in-tuberculosis-patients-protocol-for-a-double-blind-placebo-controlled-randomised-trial
#16
Omara Dogar, Deepa Barua, Melanie Boeckmann, Helen Elsey, Razia Fatima, Rhian Gabe, Rumana Huque, Ada Keding, Amina Khan, Daniel Kotz, Eva Kralikova, James N Newell, Iveta Nohavova, Steve Parrott, Anne Readshaw, Lottie Renwick, Aziz Sheikh, Kamran Siddiqi
BACKGROUND AND AIMS: Tuberculosis (TB) patients who quit smoking have much better disease outcomes than those who continue to smoke. Behavioural support combined with pharmacotherapy is the most effective strategy in helping people to quit, in general populations. However, there is no evidence for the effectiveness of this strategy in TB patients who smoke. We will assess the safety, effectiveness and cost-effectiveness of cytisine - a low-cost plant-derived nicotine substitute - for smoking cessation in TB patients compared with placebo, over and above brief behavioural support...
April 20, 2018: Addiction
https://www.readbyqxmd.com/read/29676717/-supervising-quality-of-care-through-the-patients-eyes-a-different-approach-to-inspection-is-required
#17
R J R Bouwmans, P B M Robben, R D Friele
The Netherlands Health and Youth Care Inspectorate (IGJ) wants to take the patient's perspective into account more often in its supervision of quality of care. The inspectorate already has some insight into this perspective via patients' reports; patients report complaints with the aim of preventing recurrence of the problem. However, the inspectorate does not further investigate the vast majority of these complaints and, furthermore, complaints with a clinical aspect are investigated far more often than organisational or communicational problems...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29676716/-training-to-improve-quality-of-life-and-physical-functioning-in-cancer-which-type-of-training-for-which-patient-and-at-which-moment
#18
M G Sweegers, L M Buffart
OBJECTIVE: To investigate whether the effects of exercise on quality of life and physical functioning in patients with cancer is dependent upon certain patient characteristics or on specific training programmes. DESIGN: Meta-analysis of individual patient data (IPD) and a standard meta-analysis of randomized interventional studies. METHOD: Results from various randomized interventional studies were pooled for the analysis. Differences in effects of exercise among patients with different demographic and clinical characteristics were investigated using interaction terms applied to IPD...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29676703/effect-of-intraoperative-single-shot-application-of-vancomycin-in-liver-transplant-recipients-on-postoperative-infections-with-enterococcus-faecium-and-enterococcus-faecalis
#19
Christian Siebers, Johannes Kinzinger, Ludwig C Hinske, Andreas Bauer, Patrick Scheiermann, Michael Zoller, Markus Guba, Martin Angele, Sebastian Pratschke, Thomas Weig
OBJECTIVES: Infections are major causes of morbidity and mortality in the early postoperative period after liver transplant. We observed a high rate of enterococcal infections at our center. Therefore, we added an intraoperative single shot of vancomycin to the standard regimen of meropenem given over 5 days. The aim of this study was to determine the prevalence of both Enterococcus faecium and Enterococcus faecalis infections during the first 28 days after surgery depending on the type of antibiotic prophylaxis and their implications on mortality and morbidity...
April 20, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29676694/keyhole-strategy-aiming-at-minimizing-hospital-stay-for-surgical-clipping-of-unruptured-middle-cerebral-artery-aneurysms
#20
Kentaro Mori, Kojiro Wada, Naoki Otani, Arata Tomiyama, Terushige Toyooka, Satoru Takeuchi, Takuji Yamamoto, Yasuaki Nakao, Hajime Arai
OBJECTIVE Aneurysms of the middle cerebral artery (MCA) are still most often treated by clipping through standard craniotomy, but a longer hospital stay is one of the main drawbacks of this treatment. The authors developed a pterional keyhole clipping strategy for unruptured MCA aneurysms with the intention of minimizing hospital stay. In this paper, they report on their experience with this approach and analyze the long-term neurological and radiological outcomes. METHODS A total of 160 relatively small unruptured MCA aneurysms (mean 6...
April 20, 2018: Journal of Neurosurgery
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