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Magnetic field effects

Peng Xue, Lihong Sun, Qian Li, Lei Zhang, Jinhong Guo, Zhigang Xu, Yuejun Kang
The integration of multifunctional therapeutic capabilities into a single nanosystem has attracted much attention for use as an efficient cancer therapy. However, developing biocompatible therapeutic nano-agents with desirable safety, efficiency, targeting, and synergistic effects remains challenging. Herein, we designed a class of multifunctional PEGylated magnetic nanoparticles (NPs) with a core-shell structure and polydopamine (PDA) coating, which were loaded with the anticancer drug doxorubicin (DOX) for simultaneous targeted chemotherapy and photothermal ablation of tumour cells...
September 8, 2017: Colloids and Surfaces. B, Biointerfaces
Vsevolod I Borovkov
Spin correlation effects in the geminate recombination of radical ion pairs in irradiated highly polar liquids are typically believed to be negligible due to a high escape probability for the ions. This report presents the results of an exploratory study of organic polar solvents aimed at the searching for, and estimating the magnitude of, the time-resolved magnetic field effects (TR MFEs) in the delayed radiation-induced fluorescence from diluted solutions of a luminophore. It has been found that upon the high-energy irradiation of the solutions in polar liquids, such as dichloroethane (ε≈10), methanol (ε≈33), acetonitrile (ε≈37), dimethyl formamide (ε≈37), dimethyl sulfoxide (ε≈47), ethylene carbonate (ε≈89), substantial spin coherence effects in the delayed fluorescence can be observed within a time range up to ~100 ns...
September 15, 2017: Journal of Physical Chemistry. B
Piotr Konieczny, Robert Pełka, Dominik Czernia, Robert Podgajny
Conventional (MCE) and rotating (RMCE) magnetocaloric effects have been explored in the two-dimensional (2D) coordination polymer {(tetren)H5)0.8Cu(II)4[W(V)(CN)8]4·7.2H2O}n (WCu-t; tetren = tetraethylenepentamine). The unusual magnetostructural properties were exploited, including the bilayered Prussian Blue like coordination skeleton and the XY easy-plane magnetic anisotropy based on the in-plane correlation between W(V) and Cu(II) spins of (1)/2, underlying the Berezinskii-Kosterlitz-Thouless (BKT) topological phase transition to the long-range-ordered state at TC = 33 K...
September 15, 2017: Inorganic Chemistry
Yikun Yang, Chunyi Tong, Juchang Zhong, Ruiying Huang, Weihong Tan, Zhikai Tan
Magnetic hyperthermia has been rapidly developed as a potential cancer treatment in recent years. Artificially induced hyperthermia close to a tumor can raise the temperature to 45°C causing tumor cell death. Herein, we introduce a novel method for rapid preparation of anti-cancer magnetocaloric PCL/Fe3 O4 mats capable of high-performance hyperthermia using E-jet 3D printing technology. Our 3D printed mats not only maintained the heating efficiency of traditional techniques for magnetic hyperthermia but also prolonged the effective therapy in vivo...
September 15, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Yan-Zhen Zheng, Guo-Jun Zhou, Tian Han, You-Song Ding, Nicholas F Chilton
A series of diabolo-like nonanuclear {LnIIICuII8} (Ln = Tb, Dy, Ho, Er, Tm, Yb and Y) clusters in which the LnIII ion is capped by two 8-MC-4 metallacrown ligands to form a nearly ideal square antiprismatic (SAP) coordination geometry with D4d-symmetry have been prepared. Despite the lack of crystallographic symmetry these molecules engender the lanthanide ions with highly axial mJ states. We observe that the axial/equatorial nature of the crystal field in environments close to ideal SAP geometry is very subtle and influenced by the nature of the ligand lone pairs...
September 15, 2017: Chemistry: a European Journal
Casey Burton, Yinfa Ma
The development of effective screening methods for early cancer detection is one of the foremost challenges facing modern cancer research. Urinary metabolomics has recently emerged as a potentially transformative approach to cancer biomarker discovery owing to its noninvasive sampling characteristics and robust analytical feasibility. OBJECTIVE: To provide an overview of new developments in urinary metabolomics, cover the most promising aspects of hyphenated techniques in untargeted and targeted metabolomics, and to discuss technical and clinical limitations in addition to the emerging challenges in the field of urinary metabolomics and its application to cancer biomarker discovery...
September 13, 2017: Current Medicinal Chemistry
Yuriko Suzuki, Michael Helle, Peter Koken, Marc Van Cauteren, Matthias J P van Osch
PURPOSE: Both dynamic magnetic resonance angiography (4D-MRA) and perfusion imaging can be acquired by using arterial spin labeling (ASL). While 4D-MRA highlights large vessel pathology, such as stenosis or collateral blood flow patterns, perfusion imaging provides information on the microvascular status. Therefore, a complete picture of the cerebral hemodynamic condition could be obtained by combining the two techniques. Here, we propose a novel technique for simultaneous acquisition of 4D-MRA and perfusion imaging using time-encoded pseudo-continuous arterial spin labeling...
September 14, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
Daniel R Kattnig, P J Hore
Birds have a remarkable ability to obtain navigational information from the Earth's magnetic field. The primary detection mechanism of this compass sense is uncertain but appears to involve the quantum spin dynamics of radical pairs formed transiently in cryptochrome proteins. We propose here a new version of the current model in which spin-selective recombination of the radical pair is not essential. One of the two radicals is imagined to react with a paramagnetic scavenger via spin-selective electron transfer...
September 14, 2017: Scientific Reports
Verity M McClelland
PURPOSE OF REVIEW: To demonstrate how neurophysiological tools have advanced our understanding of the pathophysiology of paediatric movement disorders, and of neuroplasticity in the developing brain. RECENT FINDINGS: Delineation of corticospinal tract connectivity using transcranial magnetic stimulation (TMS) is being investigated as a potential biomarker for response to therapy. TMS measures of cortical excitability and neuroplasticity are also being used to investigate the effects of therapy, demonstrating neuroplastic changes that relate to functional improvements...
September 12, 2017: Current Opinion in Pediatrics
Wenyu Zhao, Zhiyuan Liu, Zhigang Sun, Qingjie Zhang, Ping Wei, Xin Mu, Hongyu Zhou, Cuncheng Li, Shifang Ma, Danqi He, Pengxia Ji, Wanting Zhu, Xiaolei Nie, Xianli Su, Xinfeng Tang, Baogen Shen, Xiaoli Dong, Jihui Yang, Yong Liu, Jing Shi
The ability to control chemical and physical structuring at the nanometre scale is important for developing high-performance thermoelectric materials. Progress in this area has been achieved mainly by enhancing phonon scattering and consequently decreasing the thermal conductivity of the lattice through the design of either interface structures at nanometre or mesoscopic length scales or multiscale hierarchical architectures. A nanostructuring approach that enables electron transport as well as phonon transport to be manipulated could potentially lead to further enhancements in thermoelectric performance...
September 13, 2017: Nature
I Gross, W Akhtar, V Garcia, L J Martínez, S Chouaieb, K Garcia, C Carrétéro, A Barthélémy, P Appel, P Maletinsky, J-V Kim, J Y Chauleau, N Jaouen, M Viret, M Bibes, S Fusil, V Jacques
Although ferromagnets have many applications, their large magnetization and the resulting energy cost for switching magnetic moments bring into question their suitability for reliable low-power spintronic devices. Non-collinear antiferromagnetic systems do not suffer from this problem, and often have extra functionalities: non-collinear spin order may break space-inversion symmetry and thus allow electric-field control of magnetism, or may produce emergent spin-orbit effects that enable efficient spin-charge interconversion...
September 13, 2017: Nature
Jianping Sun, Yuanyuan Jiao, Chongli Yang, Wei Wu, Changjiang Yi, Bosen Wang, You Guo Shi, Jian Lin Luo, Yoshiya Uwatoko, Jinguang Cheng
K2Cr3As3 is a newly discovered quasi-one-dimensional superconductor with a Tc = 6.1 K and an upper critical field μ0Hc2(0) ~ 40 T three times larger than the Pauli paramagnetic limit μ0Hp that is suggestive of a spin-triplet Cooper pairing. In this paper, we have investigated the effects of hydrostatic pressure on its Tc and μ0Hc2 by measuring the ac magnetic susceptibility χ(T) under magnetic fields at various hydrostatic pressures up to 7.5 GPa. The major findings include: (1) Tc is suppressed gradually to below 2 K at 7...
September 14, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Satoshi Okamoto, Masayuki Ochi, Ryotaro Arita, Jiaqiang Yan, Nandini Trivedi
Electron correlations tend to generate local magnetic moments that usually order if the lattices are not too frustrated. The hexagonal compound SrRu2O6 has a relatively high Neel temperature but small local moments, which seem to be at odds with the nominal valence of Ru(5+) in the [Formula: see text] configuration. Here, we investigate the electronic property of SrRu2O6 using density functional theory (DFT) combined with dynamical-mean-field theory (DMFT). We find that the strong hybridization between Ru d and O p states results in a Ru valence that is closer to +4, leading to the small ordered moment ~1...
September 13, 2017: Scientific Reports
Jiangsheng Hu, JinSong Liu, Kejia Wang
We propose a new type of terahertz time-domain spectroscopy in an isotropic semiconductor wafer applied by a magnetic field in which two cross-polarization THz pulses couple with each other via the Hall effect. We built a classic theoretic model to describe cross-polarization coupling THz spectroscopy (CPCTS). Numerical simulations show that the magnetic field can clearly affect the spectral features of the two THz pulses via the Hall effect in which both the magnitude and direction of the magnetic field and the thickness of the wafer play important roles...
September 13, 2017: Scientific Reports
Anthony Kim, Stephanie Lim-Reinders, Claire McCann, Syed Bilal Ahmad, Arjun Sahgal, Justin Lee, Brian M Keller
PURPOSE: Hypofractionated partial breast irradiation (HPBI) involves treatment to the breast tumor using high doses per fraction. Recent advances in MRI-Linac solutions have potential in being applied to HPBI due to gains in the soft tissue contrast of MRI; however, there are potentially deleterious effects of the magnetic field on the dose distribution. The purpose of this work is to determine the effects of the magnetic field on the dose distribution for HPBI tumors using a tangential beam arrangement (TAN), 5-beam intensity-modulated radiation therapy (IMRT), and volumetric modulated arc therapy (VMAT)...
September 13, 2017: Journal of Applied Clinical Medical Physics
Sang Hyun Choi, So Yeon Kim, Seong Ho Park, Kyung Won Kim, Ja Youn Lee, Seung Soo Lee, Moon-Gyu Lee
BACKGROUND: Imaging studies, including computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), have an essential role in the detection and localization of colorectal liver metastasis (CRLM). PURPOSE: To systematically determine the diagnostic accuracy of multidetector row CT (MDCT), gadoxetate disodium-enhanced MRI, and PET/CT for diagnosing CRLM and the sources of heterogeneity between the reported results. STUDY TYPE: Systematic review and meta-analysis...
September 13, 2017: Journal of Magnetic Resonance Imaging: JMRI
Wensheng Xie, Qin Gao, Zhenhu Guo, Dan Wang, Fei Gao, Xiu-Mei Wang, Yen Wei, Lingyun Zhao
Integration of two or more drugs in a multi-agent delivery system has been considered to have profound impacts on both in vitro and in vivo cancer treatment due to their efficient synergistic effect. This study presents a cheap and simple chitosan hydrogel crosslinked with telechelic difunctional poly (ethylene glycol) (DF-PEG-DF) for synthesis of an injectable and self-healing thermo-sensitive dual-drug-loaded magnetic hydrogel (DDMH), which contains both doxorubicin (DOX) and docetaxel (DTX) for chemotherapy, and iron oxide for magnetic hyperthermia induced stimuli responsive drug release...
September 13, 2017: ACS Applied Materials & Interfaces
Irina V Belyanina, Tatiana N Zamay, Galina S Zamay, Sergey S Zamay, Olga S Kolovskaya, Tatiana I Ivanchenko, Valery V Denisenko, Andrey K Kirichenko, Yury E Glazyrin, Irina V Garanzha, Valentina V Grigorieva, Alexandr V Shabanov, Dmitry V Veprintsev, Alexey E Sokolov, Vladimir M Sadovskii, Ana Gargaun, Maxim V Berezovski, Anna S Kichkailo
Biomedical applications of magnetic nanoparticles under the influence of a magnetic field have been proved useful beyond expectations in cancer therapy. Magnetic nanoparticles are effective heat mediators, drug nanocarriers, and contrast agents; various strategies have been suggested to selectively target tumor cancer cells. Our study presents magnetodynamic nanotherapy using DNA aptamer-functionalized 50 nm gold-coated magnetic nanoparticles exposed to a low frequency alternating magnetic field for selective elimination of tumor cells in vivo...
2017: Theranostics
Zongfan Duan, Ying Cui, Gaoyang Zhao, Xiaoguang Li, Biaolin Peng, Chunchun Han
A La0.67Sr0.33MnO3 (LSMO) ferromagnetic layer and a Nd(3+)/Hf(4+) co-substituted Bi4Ti3O12 (Bi3.15Nd0.85Ti3-xHfxO12 (BNTHx, x = 0, 0.025, 0.05, 0.1 and 0.15)) ferroelectric layer were successively deposited onto the (00 l)-oriented LaNiO3 (LNO) layer buffered (001) Si substrate via all chemical solution deposition (CSD) method. As a result, the BNTHx/LSMO ferromagnetic-ferroelectric composite films integrated on Si substrate exhibit high c-axis orientation. The Nd(3+)/Hf(4+) co-substituted BNTHx films have the lower leakage current and the better ferroelectric properties than the mono-substituted Bi4Ti3O12 (Bi3...
September 12, 2017: Scientific Reports
Yulia I Andreeva, Andrey S Drozdov, Anna F Fakhardo, Nikolay A Cheplagin, Alexander A Shtil, Vladimir V Vinogradov
We present a new approach for obtaining magnetic nanospheres with tunable size and high magnetization. The method is implemented via controllable destabilization of a stable magnetite hydrosol with glycerol, leading to the formation of aggregates followed by their stabilization with the citrate shell. This inexpensive, simple and easily scalable approach required no special equipment. The obtained samples were characterized by high stability and magnetization over 80 emu/g. Effects of synthetic conditions on physicochemical properties of nanospheres were monitored by hydrodynamic size, zeta potential, and polydispersity of magnetite aggregates...
September 12, 2017: Scientific Reports
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