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https://www.readbyqxmd.com/read/28317338/release-of-calcium-into-the-myofibrillar-space-in-response-to-active-shortening-of-striated-muscle
#1
K A P Edman, C Caputo
AIM: The study was undertaken to explore whether shortening of striated muscle during activity is associated with release of bound Ca(2+) into the myofibrillar space as has previously been proposed in order to explain the depressant effect of active shortening. METHODS: The experiments were carried out on single muscle fibres isolated from the anterior tibialis muscle of Rana temporaria. The fibres were loaded with the calcium sensitive indicator Fluo-3. The fibres, stimulated to produce a partially fused isometric tetanus, were subjected to a shortening ramp or, alternatively, to a stretch ramp during activity while force, fibre length, sarcomere length and the Fluo-3 signal were recorded...
March 19, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28316120/synergistic-effects-of-g-csf-and-bone-marrow-stromal-cells-on-nerve-regeneration-with-acellular-nerve-xenografts
#2
Hua Jia, Ying Wang, Tao Wang, Yi Dong, Wei-Li Li, Jun-Ping Li, Wen-Zhi Ma, Xiao-Jie Tong, Zhong-Yi He
Peripheral nerve defects result in severe denervation presenting sensory and motor functional incapacitation. Currently, a satisfactory therapeutic treatment promoting the repair of injured nerves is not available. As shown in our previous study, acellular nerve xenografts (ANX) implanted with bone marrow stromal cells (BMSCs) replaced allografts and promoted nerve regeneration. Additionally, granulocyte-colony stimulating factor (G-CSF) has been proven to mobilize supplemental cells and enhance vascularization in the niche...
March 18, 2017: Synapse
https://www.readbyqxmd.com/read/28301525/muscle-activities-during-walking-and-running-at-energetically-optimal-transition-speed-under-normobaric-hypoxia-on-gradient-slopes
#3
Daijiro Abe, Yoshiyuki Fukuoka, Masahiro Horiuchi
Energy cost of transport per unit distance (CoT; J·kg-1·km-1) displays a U-shaped fashion in walking and a linear fashion in running as a function of gait speed (v; km·h-1). There exists an intersection between U-shaped and linear CoT-v relationships, being termed energetically optimal transition speed (EOTS; km·h-1). Combined effects of gradient and moderate normobaric hypoxia (15.0% O2) were investigated when walking and running at the EOTS in fifteen young males. The CoT values were determined at eight walking speeds (2...
2017: PloS One
https://www.readbyqxmd.com/read/28301328/evaluate-muscle-tension-using-intramuscular-pressure-device-in-rabbit-tibialis-anterior-model-for-improved-tendon-transfer-surgery
#4
Loribeth Evertz, Liselotte Bulstra, Alexander Shin, Kenton R Kaufman
Quantitative evaluation of passive tension in a muscle is important in tendon transfer surgeries, however, currently appropriate intraoperative measurement techniques are lacking. Intramuscular pressure (IMP) is explored as an application to access force. The tibialis anterior (TA) in New Zealand white rabbits (n=9) was used to test the hypothesis of a strong correlation between the IMP, muscle force, and length. This study also helped to develop intraoperative techniques for future human studies evaluating various insertion techniques (parallel vs...
March 16, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28290752/mri-based-assessment-of-lower-extremity-muscle-volumes-in-patients-before-and-after-acl-reconstruction
#5
Grant E Norte, Katherine R Knaus, Chris Kuenze, Geoffrey G Handsfield, Craig H Meyer, Silvia S Blemker, Joseph M Hart
CONTEXT: Study of muscle volumes in patients after anterior cruciate ligament (ACL) injury and reconstruction (ACL-R) is largely limited to cross-sectional assessment of the thigh musculature, which may inadequately describe post-traumatic and post-surgical muscle function. No studies have prospectively examined the influence of ACL injury and reconstruction on lower extremity muscle volumes. OBJECTIVE: Assess magnetic resonance imaging (MRI) derived lower extremity muscle volumes, and quantify quadriceps strength and activation in patients following ACL injury and reconstruction...
March 14, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28285649/pioglitazone-induced-improvements-in-insulin-sensitivity-occur-without-concomitant-changes-in-muscle-mitochondrial-function
#6
Sudip Bajpeyi, Magdalena Pasarica, Kevin E Conley, Bradley R Newcomer, Sharon A Jubrias, Cecilia Gamboa, Kori Murray, Olga Sereda, Lauren M Sparks, Steven R Smith
AIMS: Pioglitazone (Pio) is known to improve insulin sensitivity in skeletal muscle. However, the role of Pio in skeletal muscle lipid metabolism and skeletal muscle oxidative capacity is not clear. The aim of this study was to determine the effects of chronic Pio treatment on skeletal muscle mitochondrial activity in individuals with type 2 diabetes (T2D). MATERIALS AND METHODS: Twenty-four participants with T2D (13M/11F 53.38±2.1years; BMI 36.47±1.1kg/m(2)) were randomized to either a placebo (CON, n=8) or a pioglitazone (PIO, n=16) group...
April 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28277434/age-interactions-on-pain-sensitization-in-patients-with-severe-knee-osteoarthritis-and-controls
#7
Kristian Kjær Petersen, Lars Arendt-Nielsen, Sara Finocchietti, Rogerio Pessoto Hirata, Ole Simonsen, Mogens Berg Laursen, Thomas Graven-Nielsen
OBJECTIVES: Widespread pressure hyperalgesia, facilitated temporal summation of pain (TSP), and impaired conditioned pain modulation (CPM) have been found in knee osteoarthritis (KOA) patients compared with controls and these parameters have further been suggested to be altered in the elderly. This study investigated the influence of age on pressure hyperalgesia, TSP, and CPM in patients with KOA and controls. METHODS: One-hundred-thirty-three severe KOA patients and 50 age and sex-matched asymptomatic controls were assessed by cuff algometry and handheld pressure algometry...
March 8, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28277422/neuromuscular-adaptations-to-short-term-high-intensity-interval-training-in-female-ice-hockey-players
#8
Juho-Ville Kinnunen, Harri Piitulainen, Jarmo M Piirainen
High-intensity interval training (HIIT) related neuromuscular adaptations, changes in force production and on-ice performance were investigated in female ice-hockey players during pre-season. Fourteen Finnish championship level ice hockey players (average age 22 ± 3 years) participated in 2½-week HIIT. Both spinal (H-reflex) and supraspinal (V-wave) neuromuscular responses of the soleus muscle were recorded before and after the training period. Static jump (SJ) and countermovement jump (CMJ) heights, plantar flexor maximal voluntary contraction (MVC) and rate of force development (RFD) were measured...
March 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28272925/a-biomechanical-comparison-of-allograft-tendons-for-ligament-reconstruction
#9
Jeremiah E Palmer, Joseph P Russell, Jason Grieshober, Abigail Iacangelo, Benjamin A Ellison, T Dylan Lease, Hyunchul Kim, R Frank Henn, Adam H Hsieh
BACKGROUND: Allograft tendons are frequently used for ligament reconstruction about the knee, but they entail availability and cost challenges. The identification of other tissues that demonstrate equivalent performance to preferred tendons would improve limitations. Hypothesis/Purpose: We compared the biomechanical properties of 4 soft tissue allograft tendons: tibialis anterior (TA), tibialis posterior (TP), peroneus longus (PL), and semitendinosus (ST). We hypothesized that allograft properties would be similar when standardized by the looped diameter...
March 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28272859/coverage-of-extensive-tibial-bone-exposure-in-burn-patients-with-three-local-flaps
#10
N Lahouel, P Mokwatlo, E Ndobe
Covering tibial bone exposure from third degree burns to the lower limbs is a challenging task for the plastic surgeon. We present our experience of covering tibial exposure from burns in three different patients, where four limbs were involved and three muscular flaps were used in conjunction with one another; i.e. the tibialis anterior flap, the medial gastrocnemius flap and the hemisoleus flap. Through the use of this technique, tibial bone exposure, ranging from 15-30 cm, was successfully covered. This technique constitutes a good solution for surgically challenging wounds...
November 2016: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28272858/coverage-of-extensive-tibial-bone-exposure-in-burn-patients-with-three-local-flaps
#11
N Lahouel, P Mokwatlo, E Ndobe
Covering tibial bone exposure from third degree burns to the lower limbs is a challenging task for the plastic surgeon. We present our experience of covering tibial exposure from burns in three different patients, where four limbs were involved and three muscular flaps were used in conjunction with one another; i.e. the tibialis anterior flap, the medial gastrocnemius flap and the hemisoleus flap. Through the use of this technique, tibial bone exposure, ranging from 15-30 cm, was successfully covered. This technique constitutes a good solution for surgically challenging wounds...
November 2016: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28270048/influence-of-transcutaneous-electrical-nerve-stimulation-conditions-on-disynaptic-reciprocal-ia-inhibition-and-presynaptic-inhibition-in-healthy-adults
#12
Kazuya Takeda, Shigeo Tanabe, Soichiro Koyama, Kosuke Ushiroyama, Yuki Naoi, Ikuo Motoya, Hiroaki Sakurai, Yoshikiyo Kanada
This study investigated the influence of stimulus conditions of transcutaneous electrical nerve stimulation (TENS) on disynaptic reciprocal Ia inhibition (RI) and presynaptic inhibition (D1 inhibition) in healthy adults. Eight healthy participants received TENS (stimulus frequencies of 50, 100, and 200 Hz) over the deep peroneal nerve and tibialis anterior (TA) muscle in the resting condition for 30 min. At pre- and post-intervention, the RI from the TA to the soleus (SOL) and D1 inhibition of the SOL alpha motor neuron were assessed by evoked electromyography...
March 2017: Somatosensory & Motor Research
https://www.readbyqxmd.com/read/28269583/exercise-system-for-eccentric-tibialis-anterior-contraction-to-improve-ambulatory-function
#13
Shota Itoh, Keisuke Kubota, Kunihiro Ogata, Toshiaki Tsuji
This study has developed a device and system for the exercise of eccentric contraction of the tibialis anterior, with the objective of maintaining ambulatory function. A system was built that allows for exercises of appropriate load and speed, by providing the trainee with force data in the form of visual feedback. An experimental verification with two healthy participants shows small variation in the Myoelectric data during the repetitive exercise. The result suggest the possibility of higher reproducibility of the proposed exercise in comparison with manual exercise...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269308/corticomuscular-coherence-variation-throughout-the-gait-cycle-during-overground-walking-and-ramp-ascent-a-preliminary-investigation
#14
Anna T Winslow, Justin Brantley, Fangshi Zhu, Jose L Contreras Vidal, He Huang
Recent designs of neural-machine interfaces (NMIs) incorporating electroencephalography (EEG) or electromyography (EMG) have been used in lower limb assistive devices. While the results of previous studies have shown promise, a NMI which takes advantage of early movement-related EEG activity preceding movement onset, as well as the improved signal-to-noise ratio of EMG, could prove to be more accurate and responsive than current NMI designs based solely on EEG or EMG. Previous studies have demonstrated that the activity of the sensorimotor cortex is coupled to the firing rate of motor units in lower limb muscles during voluntary contraction...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268660/estimation-of-gait-parameter-using-sonoelastography-in-children-with-cerebral-palsy
#15
M Mansouri, P M Birgani, M R Kharazi, M Lotfian, M Naeimipoor, M M Mirbagheri
We aimed to study the relationship between neuromuscular abnormalities associated with spasticity and gait impairments in spastic children with hemiplegia cerebral palsy (CP). Neuromuscular abnormalities of the tibialis anterior and medial gastrocnemius muscles of the spastic ankle were quantified using sonoelastography with two major features; i.e. entropy and histogram ratio of sonoelastography images. Gait impairments were evaluated in the gait laboratory using motion capture system, and the spatial and temporal features were extracted...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268364/3d-detection-of-periodic-limb-movements-in-sleep
#16
Heinrich Garn, Bernhard Kohn, Klaus Dittrich, Christoph Wiesmeyr, Gerhard Kloesch, Robert Stepansky, Markus Wimmer, Osman Ipsiroglu, Dieter Grossegger, Manuel Kemethofer, Stefan Seidel
The standard polysomnographic method for detecting periodic limb movements in sleep (PLMS) includes measuring the electromyography (EMG) signals from electrodes at the left and right tibialis anterior muscles. This procedure has disadvantages as the cabling affects the patients quality of sleep and the electrodes tend to come off during the night, deteriorating data quality. We used contactless monitoring of body movements by a 3D time-of-flight camera mounted above the bed. Changes in the 3D silhouette indicate motion...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268142/an-innovative-anchoring-technique-for-anterior-transfer-of-the-tibialis-posterior-tendon
#17
Po-Chih Shen, Shih-Hsiang Chou, Jian-Chih Chen, Shu-Jung Chen, Yin-Chun Tien
Favorable results have been reported for tibialis posterior tendon transfers, which can effectively restore the dorsiflexion of the ankle and normal heel-to-toe gait. However, the commonly used methods for anchoring the transplanted tendon have some drawbacks. Therefore, we developed a new tendon-anchoring method to improve fixation of the transferred tendon and reduce the related complications. The new method entails tying the anchoring suture to the navicular bone instead of the button on the plantar foot to avoid wound complications...
March 3, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28265148/the-effects-of-functional-electrical-stimulation-on-muscle-tone-and-stiffness-of-stroke-patients
#18
Sang-Hyun Moon, Jung-Hyun Choi, Si-Eun Park
[Purpose] The purpose of this study was to determine the effects of functional electrical stimulation on muscle tone and stiffness in stroke patients. [Subjects and Methods] Ten patients who had suffered from stroke were recruited. The intervention was functional electrical stimulation on ankle dorsiflexor muscle (tibialis anterior). The duration of functional electrical stimulation was 30 minutes, 5 times a week for 6 weeks. The Myoton was used a measure the muscle tone and stiffness of the gastrocnemius muscle (medial and lateral part) on paretic side...
February 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28261743/lllt-actives-mmp-2-and-increases-muscle-mechanical-resistance-after-nerve-sciatic-rat-regeneration
#19
Rodrigo Antonio Carvalho Andraus, Luciana Prado Maia, Anderson Diogo de Souza Lino, Karen Barron Parron Fernandes, Marcos Vinícius de Matos Gomes, Rinaldo Roberto de Jesus Guirro, Cláudio Henrique Barbieri
The purpose of this study was to analyze the low-level laser therapy (LLLT) on metalloproteinase expression and the mechanical strength of skeletal muscle regeneration after peripheral nerve injury. Rats were subjected to crush injury of the right sciatic nerve, followed by LLLT (830 nm, 35, 70, 140, and 280 J/cm(2)) for 21 consecutive days. Functional gait analysis was performed at weekly intervals and the animals were sacrificed after the last evaluation at day 21 for collection of the gastrocnemius muscles, which were submitted to analysis of resistance, and the tibialis anterior, for evaluation of metalloproteinase-2 (MMP-2)...
March 6, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28258311/recognition-of-peroneal-intraneural-ganglia-in-an-historical-cohort-with-negative-mris
#20
Thomas J Wilson, Marie-Nöelle Hébert-Blouin, Naveen S Murthy, Kimberly K Amrami, Robert J Spinner
BACKGROUND: The objective of this study was to review an historical cohort of patients with peroneal neuropathy and magnetic resonance imaging (MRI) read as negative for mass or cyst to determine if occult peroneal intraneural ganglion cysts can be identified on subsequent imaging review and to use this as an estimation of how under-recognized this pathologic entity is. METHOD: The patient cohort utilized in this study was a previously published control cohort of 11 patients with peroneal neuropathy and MRI read as negative for mass or cyst...
March 3, 2017: Acta Neurochirurgica
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