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Raynaud guidelines

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https://www.readbyqxmd.com/read/26808752/the-role-of-botulinum-toxin-a-in-the-treatment-of-raynaud-phenomenon
#1
Francesco Segreto, Giovanni Francesco Marangi, Vincenzo Cerbone, Paolo Persichetti
Raynaud phenomenon (RP) is a transient digital ischemia that occurs after exposure to cold temperature or emotional distress. It presents with a triphasic course: the initial white phase is followed by cyanotic discoloration and, subsequently, erythema. The attacks may be associated with pain, paresthesia, and complicate with nonhealing ulceration often leading to amputation. To date, there are no clear-cut therapeutic guidelines and many medications are used off-label. Encouraging results were reported with the use of botulinum neurotoxin-A (BoNT-A)...
September 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/26546402/management-of-malignant-pleural-mesothelioma-a-french-multicenter-retrospective-study-gfpc-0802-study
#2
MULTICENTER STUDY
C Raynaud, L Greillier, J Mazieres, I Monnet, B Mastroianni, G Robinet, G Fraboulet, A Dixmier, H Berard, R Lamy, J Letreut, H Lena, G Oliviero, S Botta, A Vergnenegre, I Borget, C Chouaid
BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare disease with poor prognosis in spite of significant improvement in survival, due to new chemotherapy regimens. We describe here patients' profiles and management in daily practice in France. METHODS: Observational retrospective study. Data were collected from medical files. All patients with histologically proven MPM diagnosed from January 2005 to December 2008 were included in the participating sites. RESULTS: Four hundred and six patients were included in 37 sites: mean age 68...
2015: BMC Cancer
https://www.readbyqxmd.com/read/25874345/new-acr-eular-guidelines-for-systemic-sclerosis-classification
#3
Sindhu R Johnson
The American College of Rheumatology and European League Against Rheumatism classification criteria for systemic sclerosis are a significant advancement in the field. This article describes the innovative, rigorous, criteria development strategy that was used. The new criteria build upon previous criteria by incorporating important elements (proximal scleroderma, sclerodactyly, digital pits, pulmonary fibrosis, Raynaud's phenomenon, and scleroderma specific autoantibodies). The new criteria add emphasis to the vasculopathic manifestations, and include the early manifestation of puffy fingers...
May 2015: Current Rheumatology Reports
https://www.readbyqxmd.com/read/25646291/influence-of-diagnostic-criteria-on-the-interpretation-of-adrenal-vein-sampling
#4
MULTICENTER STUDY
Gaëlle Lethielleux, Laurence Amar, Alain Raynaud, Pierre-François Plouin, Olivier Steichen
Guidelines promote the use of adrenal vein sampling (AVS) to document lateralized aldosterone hypersecretion in primary aldosteronism. However, there are large discrepancies between institutions in the criteria used to interpret its results. This study evaluates the consequences of these differences on the classification and management of patients. The results of all 537 AVS procedures performed between January 2001 and July 2010 in our institution were interpreted with 4 diagnostic criteria used in experienced institutions where AVS is performed without cosyntropin (Brisbane, Padua, Paris, and Turin) and with criteria proposed by a recent consensus statement...
April 2015: Hypertension
https://www.readbyqxmd.com/read/25449678/a-prisma-driven-systematic-review-for-predictive-risk-factors-of-digital-ulcers-in-systemic-sclerosis-patients
#5
REVIEW
I Silva, J Almeida, C Vasconcelos
Vasculopathy has a major role in the pathogenesis and tissue injury in systemic sclerosis (SSc). Raynaud's phenomenon (RP) is frequently the first clinical manifestation of SSc preceding by years other clinical manifestations. RP in SSc patients is frequent, often very severe and long lasting. The repeated bouts of RP lead to prolonged digital ischemia that may progress to digital ulceration or in extreme to critical digital ischemia with gangrene. Digital ulcers (DU) are a true burden for all patients. They are very painful, with a long and slow healing course, have high risk of infection and are extremely disabling...
February 2015: Autoimmunity Reviews
https://www.readbyqxmd.com/read/24720440/use-of-bosentan-for-digital-ulcers-related-to-systemic-sclerosis-a-real-life-retrospective-french-study-of-89-patients-treated-since-specific-approval
#6
MULTICENTER STUDY
C Agard, P H Carpentier, L Mouthon, P Clerson, V Gressin, A Bérezné, E Diot, P Jego, C Lok, A Sparsa, E Chatelus, A Khau Van Kien, I Quéré, J Sibilia, E Hachulla
OBJECTIVES: Ischaemic digital ulcers (DUs) are a common complication of systemic sclerosis (SSc). This study aimed to characterize patients with SSc and ongoing DUs treated with the endothelin receptor antagonist bosentan in clinical practice in France. METHOD: An observational, retrospective, longitudinal study was conducted in 10 French expert centres. Medical records from randomly selected adult SSc patients who received treatment with bosentan for DU prevention from March 2007 to December 2010 were analysed...
2014: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/24034643/-minimal-work-up-for-raynaud-syndrome-a-consensus-report-microcirculation-working-group-of-the-soci%C3%A3-t%C3%A3-fran%C3%A3-aise-de-m%C3%A3-decine-vasculaire
#7
M-A Pistorius, P-H Carpentier
About ten to fifteen percent of the French population suffer from Raynaud's phenomenon. Most of the time, it is considered as primary Raynaud's phenomenon, without underlying disease. The aim of this expert consensus from the "microcirculation group" for the French Society of Vascular Medicine and the French Society for Microcirculation, was to define clinical guidelines in patients consulting for Raynaud's phenomenon. The recommended minimal screening includes clinical examination, nailfold capillaroscopy and antinuclear antibodies...
August 2013: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/23917809/effectiveness-and-safety-of-phosphodiesterase-5-inhibitors-in-patients-with-cardiovascular-disease-and-hypertension
#8
REVIEW
Steven G Chrysant
Phosphodiesterase 5 (PDE 5) inhibitors are selective inhibitors of the enzyme PDE 5, which catalyzes the hydrolysis of cyclic guanosine monophosphate (cGMP), a potent vasodilator and nitric oxide (NO) donor, to its corresponding metabolites (monophosphates). The enzyme PDE 5 is widely distributed in the body, including the heart and blood vessels. Because of its distribution, it was hypothesized that its inhibition could lead to significant coronary vasodilation, which would benefit patients with coronary artery disease (CAD)...
October 2013: Current Hypertension Reports
https://www.readbyqxmd.com/read/23746815/-pulmonary-rehabilitation-and-non-invasive-ventilation-before-lung-surgery-in-very-high-risk-patients
#9
P Bagan, V Oltean, A Ben Abdesselam, B Dakhil, C Raynaud, J-C Couffinhal, H De Crémoux
INTRODUCTION: The benefits of a rehabilitation program before surgical lung cancer resection remain to be defined. The purpose of this prospective observational study was to assess the effects of rehabilitation together with the use of noninvasive ventilation (NIV) in patients who were at a high operative risk. METHODS: Between January 2010 and June 2011, 20 consecutive patients (16 males, four females, mean age: 66 years [44-79]) with a clinical N0 non-small cell lung cancer were included...
May 2013: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/23538667/vitamin-d-supplementation-in-older-adults-searching-for-specific-guidelines-in-nursing-homes
#10
REVIEW
Y Rolland, P de Souto Barreto, G Abellan Van Kan, C Annweiler, O Beauchet, H Bischoff-Ferrari, G Berrut, H Blain, M Bonnefoy, M Cesari, G Duque, M Ferry, O Guerin, O Hanon, B Lesourd, J Morley, A Raynaud-Simon, G Ruault, J-C Souberbielle, B Vellas
BACKGROUND: The prevalence of vitamin D insufficiency is very high in the nursing home (NH) population. Paradoxically, vitamin D insufficiency is rarely treated despite of strong clinical evidence and recommendations for supplementation. This review aims at reporting the current knowledge of vitamin D supplementation in NH and proposing recommendations adapted to the specificities of this institutional setting. DESIGN: Current literature on vitamin D supplementation for NH residents was narratively presented and discussed by the French Group of Geriatrics and Nutrition...
April 2013: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/23404236/peripheral-neuropathy-a-complication-of-systemic-sclerosis
#11
Tracy M Frech, Gordon Smith, Melissa Reily, James Chamberlain, Maureen A Murtaugh, Jason Penrod, Michael J Battistone, Barry M Stults
We performed bedside testing for peripheral neuropathy in our systemic sclerosis (SSc) population to determine whether foot care guidelines should be developed for SSc. Twenty consecutive SSc patients and 20 healthy control (HC) patients were evaluated for peripheral neuropathy in both feet using the 10-g Semmes-Weinstein monofilament examination (SWME) and 128 Hz vibration sensation using the on-off method. Independent, blinded, vibratory sensation, and SWME evaluations were performed on each subject by two investigators who had completed a training session to standardize each exam...
June 2013: Clinical Rheumatology
https://www.readbyqxmd.com/read/23316984/cutaneous-cryosurgery
#12
Ethan E Zimmerman, Paul Crawford
Cutaneous cryosurgery refers to localized application of freezing temperatures to achieve destruction of skin lesions. It can be used to treat a broad range of benign and premalignant skin conditions, and certain malignant skin conditions, with high cure rates. Cellular destruction is accomplished by delivery of the cryogen via dipstick, probe, or spray techniques. It is widely used in primary care because of its safety, effectiveness, low cost, ease of use, good cosmetic results, and lack of need for anesthesia...
December 15, 2012: American Family Physician
https://www.readbyqxmd.com/read/23294726/prostate-specific-antigen-psa-concentrations-in-hypogonadal-men-during-6-years-of-transdermal-testosterone-treatment
#13
MULTICENTER STUDY
Jean-Pierre Raynaud, Jean Gardette, Jacques Rollet, Jean-Jacques Legros
UNLABELLED: WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Hypogonadism affects an estimated 2-4 million men in the USA, but only 5% receive treatment. Testosterone replacement therapy reduces the effects of testosterone deficiency on sexual function, mood and energy in hypogonadal patients. Long-term hypogonadism management requires testosterone treatment to restore serum concentrations of testosterone and its active metabolites, within physiological ranges; a testosterone preparation that achieves physiological plasma concentrations without supra-physiological escape is a preferred option...
May 2013: BJU International
https://www.readbyqxmd.com/read/22749761/-minimal-work-up-for-raynaud-syndrome-a-consensus-report-microcirculation-working-group-of-the-french-vascular-medicine-society
#14
M-A Pistorius, P-H Carpentier
About ten to fifteen percent of the French population suffer from Raynaud's phenomenon. Most of the time, it is considered as primary Raynaud's phenomenon, without underlying disease. The aim of this expert consensus from the "microcirculation group" for the French Society of Vascular Medicine and the French Society for Microcirculation, was to define clinical guidelines in patients consulting for Raynaud's phenomenon. The recommended minimal screening includes clinical examination, nailfold capillaroscopy and antinuclear antibodies...
July 2012: Journal des Maladies Vasculaires
https://www.readbyqxmd.com/read/22748858/-the-vaccination-of-older-adults-a-challenge-for-the-future
#15
Christine Bonnal, Corinne Desaint, Agathe Raynaud-Simon, Virginie Fossey-Diaz, Marie Lise Gougeon, Jean Christophe Lucet, Odile Launay
In developed countries, the population is getting older and the prevention of infectious diseases is therefore a major public health issue for elderly. Infectious diseases preventable by vaccination, including influenza, pneumococcal infection, pertussis, herpes zoster infections, and to a lesser extent, diphtheria and poliomyelitis, are direct or indirect causes of hospitalization. Few data are available on the proportion of vaccinated elderly, the impact of the under nutrition, or immunosenescence on the quality of the immune response to vaccination and the level of protection...
March 2013: La Presse Médicale
https://www.readbyqxmd.com/read/22691207/best-practices-in-scleroderma-an-analysis-of-practice-variability-in-ssc-centres-within-the-canadian-scleroderma-research-group-csrg
#16
Sarah Harding, Sarit Khimdas, Ashley Bonner, Murray Baron, Janet Pope
OBJECTIVES: There is currently no consensus on best practice in systemic sclerosis (SSc). To determine if variability in treatment and investigations exists, practices among Canadian Sclerodermia Research Group (CSRG) centres were compared. METHODS: Prospective clinical and demographic data from adult SSc patients are collected annually from 15 CSRG treatment centres. Laboratory parameters, self-reported socio-demographic questionnaires, current and past medications and disease outcome measures are recorded...
March 2012: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/22247347/agreement-with-guidelines-from-a-large-database-for-management-of-systemic-sclerosis-results-from-the-canadian-scleroderma-research-group
#17
COMPARATIVE STUDY
Janet Pope, Sarah Harding, Sarit Khimdas, Ashley Bonner, Murray Baron
OBJECTIVE: We determined congruence with published guidelines from the European League Against Rheumatism (EULAR)/EULAR Scleroderma Trials and Research group, for systemic sclerosis (SSc) investigations and treatment practices within the Canadian Scleroderma Research Group (CSRG). METHODS: Investigations and medication use for SSc complications were obtained from records of patients with SSc in the CSRG to determine adherence to guidelines for patients enrolled before and after the guidelines were published...
March 2012: Journal of Rheumatology
https://www.readbyqxmd.com/read/22147109/comparison-of-qualitative-and-quantitative-analysis-of-capillaroscopic-findings-in-patients-with-rheumatic-diseases
#18
COMPARATIVE STUDY
Sevdalina Nikolova Lambova, Walter Hermann, Ulf Müller-Ladner
No guidelines for the application of qualitative and quantitative analysis of the capillaroscopic examination in the rheumatologic practice exist. The aims of the study were to compare qualitative and quantitative analysis of key capillaroscopic parameters in patients with common rheumatic diseases and to assess the reproducibility of the qualitative evaluation of the capillaroscopic parameters, performed by two different investigators. Two hundred capillaroscopic images from 93 patients with different rheumatic diseases were analysed quantitatively and qualitatively by two different investigators...
December 2012: Rheumatology International
https://www.readbyqxmd.com/read/21961408/you-re-the-flight-surgeon-raynaud-s-disease
#19
Craig R Pack
No abstract text is available yet for this article.
October 2011: Aviation, Space, and Environmental Medicine
https://www.readbyqxmd.com/read/21864863/study-of-the-spatial-and-historical-distribution-of-sediment-inorganic-contamination-in-the-toulon-bay-france
#20
Erwan Tessier, Cédric Garnier, Jean-Ulrich Mullot, Véronique Lenoble, Mireille Arnaud, Michel Raynaud, Stéphane Mounier
This study presents trace elements levels in surface and deep sediments of the Toulon bay (SE France) subjected to anthropogenic inputs (navy base, harbors, etc.). The studied elements (As, Cd, Cr, Cu, Hg, Ni, Pb, Zn) are defined as priority contaminants in aquatic systems. Fifty-five points scattered on the entire bay were sampled, allowing the determination of contaminants distribution with a high resolution. Several approaches were used to assess the degree of contamination and the potential toxicity of the Toulon bay sediments: comparison to the French legislation, surface-weighted average metal concentrations, enrichment factors (EF), geoaccumulation indices (Igeo), trace element stock calculation and comparison to sediment quality guidelines...
October 2011: Marine Pollution Bulletin
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