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corticosteroid pneumonia

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https://www.readbyqxmd.com/read/29764749/prognosis-of-chronic-pulmonary-aspergillosis-in-patients-with-pulmonary-non-tuberculous-mycobacterial-disease
#1
Maiko Naito, Yu Kurahara, Shiomi Yoshida, Naoya Ikegami, Takehiko Kobayashi, Shojiro Minomo, Kazunobu Tachibana, Kazunari Tsuyuguchi, Seiji Hayashi, Katsuhiro Suzuki
BACKGROUND: Pulmonary non-tuberculous mycobacterial disease (PNTM) is a known risk factor for chronic pulmonary aspergillosis (CPA). However, few studies have focused on the prognosis of PNTM-associated CPA. In the present investigation, we aimed to elucidate the clinical course and prognostic factors of CPA in patients with PNTM. METHODS: We retrospectively investigated the medical records of 62 patients with CPA and a history of PNTM who were admitted to Kinki-chuo Chest Medical Center between 2010 and 2015...
May 11, 2018: Respiratory Investigation
https://www.readbyqxmd.com/read/29741130/quantitative-characterization-of-the-relationship-between-levels-of-extended-corticosteroid-use-and-related-adverse-events-in-a-us-population
#2
J Bradford Rice, Alan G White, Michaela Johnson, Aneesha Wagh, Yimin Qin, Laura Bartels-Peculis, Gosia Ciepielewska, Winnie W Nelson
OBJECTIVE: This retrospective study assessed the incidence and timing of adverse events (AEs) among patients prescribed varying dose levels of corticosteroids in the US. METHODS: Patients with selected autoimmune or inflammatory disease diagnoses between 2006 and 2015 were identified from a privately-insured administrative database. Patients were stratified into treatment cohorts based on dosage and length of corticosteroid use: intermittent use with duration <60 days, and three extended use cohorts with duration ≥60 days at low (≤7...
May 9, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29735492/asthmatic-adult-with-marked-blood-eosinophilia-is-it-truly-asthma
#3
Shera Tan, Angela Takano, Aloysius Ho, Keng Leong Tan
A middle-aged woman presented with symptoms suggestive of allergic asthma but with markedly elevated peripheral eosinophilia. She did not respond to inhaled corticosteroids, thereby prompting further investigations. Chest radiograph was normal. CT of the chest revealed bi-apical ground glass opacities. Bronchoalveolar lavage revealed predominantly eosinophilic yield. Autoimmune screen was negative. Bone marrow biopsy showed a normocellular marrow with increased eosinophils. A diagnosis of chronic eosinophilic pneumonia (CEP) was made after exclusion of other causes of eosinophilia...
May 7, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29735405/eosinophilic-pneumonias
#4
REVIEW
James Allen, Michael Wert
The eosinophilic pneumonias are a heterogeneous group of diseases characterized by an increase in eosinophils in lung tissue or bronchoalveolar lavage fluid. Many, but not all, of the eosinophilic pneumonias are also associated with a peripheral blood eosinophilia. The etiologies of eosinophilic lung disease are wide ranging and include parasitic infections, medications or other toxins, autoimmune and inflammatory disease, and malignancies. Some eosinophilic pneumonias have no proven cause or inciting event and are classified as idiopathic...
May 4, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29731926/practical-approach-to-lung-health-experience-from-the-republic-of-macedonia
#5
Biljana Ilievska-Poposka, Maja Zakoska, Stefan Talevski
BACKGROUND: Among the adults and children aged 5 yrs who attend PHC settings, 20-30% seeks to care for respiratory symptoms. Over 80-90% of the respiratory patients suffer from acute respiratory infections (ARI), followed by chronic obstructive pulmonary diseases (COPD), asthma, and less frequently with pneumonia and tuberculosis (TB). To improve the quality of care in patients who seek assistance for respiratory symptoms in PHC settings and the efficiency of respiratory service delivery within healthcare systems, WHO has designated several initiatives among which one is PAL (Practical Approach to Lung Health)...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29717396/acute-fibrinous-and-organizing-pneumonia-as-initial-presentation-of-primary-sj%C3%A3-gren-s-syndrome-a-case-report-and-literature-review
#6
REVIEW
Yukai Wang, Shucan Zhao, Guangzhou Du, Songkun Ma, Qisheng Lin, Jianqun Lin, Kedi Zheng, Guohong Zhang, Marco Matucci-Cerinic
Acute fibrinous and organizing pneumonia (AFOP) is a new histopathological pattern of acute lung injury first described by Beasley et al. in 2002. Hallmarks of pathological findings are characterized by the presence of intra-alveolar fibrin in the form of fibrin "balls" within the alveolar spaces and organizing pneumonia with a patchy distribution. Patients with AFOP may have an acute or subacute clinical presentation. Although the pathogenesis of AFOP is not fully elucidated, it may be associated with autoimmune diseases...
May 2, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29705221/early-corticosteroids-for-pneumocystis-pneumonia-in-adults-without-hiv-are-not-associated-with-better-outcome
#7
Patrick M Wieruszewski, Jason N Barreto, Erin Frazee, Craig E Daniels, Pritish K Tosh, Ross A Dierkhising, Kristin C Mara, Andrew H Limper
BACKGROUND: Evidence supporting adjunctive corticosteroids during the treatment of Pneumocystis pneumonia (PcP) in adults without human immunodeficiency virus (HIV) is minimal and controversial. METHODS: This retrospective cohort study included PcP-positive, hospitalized patients without HIV admitted to Mayo Clinic from 2006 to 2016. Change from baseline in the respiratory component of the Sequential Organ Failure Assessment score (SOFAresp ) at day 5 was compared between early (within 48 hours) steroid recipients and non-recipients utilizing multivariable logistic regression and in a propensity-matched analysis...
April 26, 2018: Chest
https://www.readbyqxmd.com/read/29692381/current-status-of-community-acquired-pneumonia-in-patients-with-chronic-obstructive-pulmonary-disease
#8
REVIEW
De-Shun Liu, Xiu-Di Han, Xue-Dong Liu
Objective: Worldwide, community-acquired pneumonia (CAP) is a common infection that occurs in older adults, who may have pulmonary comorbidities, including chronic obstructive pulmonary disease (COPD). Although there have been clinical studies on the coexistence of CAP with COPD, there remain some controversial findings. This review presents the current status of COPD in CAP patients, including the disease burden, clinical characteristics, risk factors, microbial etiology, and antibiotic treatment...
May 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29690685/-current-status-of-diagnosis-and-treatment-of-community-acquired-pneumonia-in-shanghai-revealed-by-a-questionnaire-analysis
#9
J Liu, J Zhang, Q J Cheng, J F Xu, Z J Jie, Y Jiao, Y Huang, J M Qu
Objective: To understand the current status of diagnosis and treatment of community-acquired pneumonia (CAP) among doctors in various hospitals across Shanghai, for the purpose of promoting the 2016 clinical practice guidelines for adult CAP of China. Methods: A questionnaire was designed to address the common questions in CAP management. The responses were collected via WeChat and the data were analyzed. Results: A total of 1 254 valid questionnaires were received, 46.1% from tertiary , 26.4% from secondary and 27...
April 12, 2018: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29666203/efficacy-and-safety-of-pulmonary-application-of-corticosteroids-in-preterm-infants-with-respiratory-distress-syndrome-a-systematic-review-and-meta-analysis
#10
Mahin Delara, Bhupendrasinh F Chauhan, Mê-Linh Le, Ahmed M Abou-Setta, Ryan Zarychanski, Geert W 'tJong
BACKGROUND: Systemic corticosteroids as the frontline treatment of respiratory distress syndrome (RDS) in preterm infants are associated with adverse effects on growth and neurodevelopmental outcome, but the pulmonary administration of steroids may help prevent the development of bronchopulmonary dysplasia (BPD) without these side effects. OBJECTIVES: To evaluate the efficacy and safety of pulmonary application of corticosteroids in preterm infants with RDS. METHODS: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, ClinicalTrials...
April 17, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29663063/-treatment-with-pd-1-pd-l1-and-ctla-4-immune-checkpoint-inhibitors-immune-mediated-side-effects
#11
REVIEW
M-O Grimm, H Oppel-Heuchel, S Foller
Immune checkpoint inhibitors are a new standard therapy for advanced or metastatic urothelial as well as renal cell carcinoma. Atezolizumab and Pembrolizumab have been approved for the treatment of cisplatin-ineligible patients with transitional call cancer in the 1st line setting; both antibodies and Nivolumab may also be used after platinum based prior therapy. Regarding renal cell carcinoma approval for 1st line treatment with the combination of Nivolumab and Ipilimumab for patients at intermediate or high risk (IMDC) is currently expected...
May 2018: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29661670/-community-acquired-pneumonia-in-patients-with-chronic-obstructive-pulmonary-disease-treated-with-inhaled-corticosteroids-or-other-bronchodilators-study-pneumocort
#12
Rosa Morros, Cristina Vedia, Maria Giner-Soriano, Aina Casellas, Ester Amado, Jose Miguel Baena
OBJECTIVES: To analyse the risk of pneumonia and/or exacerbations in patients with chronic obstructive pulmonary disease (COPD) who receive treatment with inhaled corticosteroids (CI), in comparison with those who are not treated with inhaled corticosteroids (NCI). To estimate the risk of pneumonia according to CI dose. DESIGN: Population-based cohort study. SETTING: Primary Healthcare. Institut Català de la Salut. PARTICIPANTS: Patients ≥45 years-old diagnosed with COPD between 2007 and 2009 in the Information System for Research in Primary Care (SIDIAP)...
April 13, 2018: Atencion Primaria
https://www.readbyqxmd.com/read/29650563/blood-eosinophil-count-and-risk-of-pneumonia-hospitalisations-in-individuals-with-copd
#13
Signe Vedel-Krogh, Børge G Nordestgaard, Peter Lange, Jørgen Vestbo, Sune F Nielsen
Introduction: Blood eosinophil count in COPD is associated with higher exacerbation rate and favorable response to corticosteroids; however, frequent exacerbations and use of inhaled corticosteroids could also elevate pneumonia risk. We tested the hypothesis that high blood eosinophil counts are associated with high risk of pneumonia in individuals with severe COPD from the general population. Methods: We included 7,180 individuals with COPD, including 643 with FEV1 <50% of the predicted value from the Copenhagen General Population Study, from 2003-2011...
April 12, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29649357/amiodarone-induced-interstitial-and-organizing-pneumonia-reversed-with-steroids
#14
Kshitij Chatterjee, Yogita M Rochlani, Kevin Kuriakose, AndrewDunn, Khaled Khasawneh, Hakan Paydak
Amiodarone is a widely used antiarrhythmic agent for supraventricular and ventricular tachyarrhythmias. It is known to cause pulmonary toxicity, which can manifest in a variety of presentations, ranging from asymptomatic to fatal. We present a case of chronic interstitial pneumonia with organizing pneumonia induced by amiodarone that was successfully treated with drug cessation and use of corticosteroids. The patient experienced complete resolution of symptoms and full recovery of lung function after the course of steroids...
June 2017: Journal of the Arkansas Medical Society
https://www.readbyqxmd.com/read/29629405/evaluation-of-systemic-corticosteroids-in-patients-with-an-acute-exacerbation-of-copd-and-a-diagnosis-of-pneumonia
#15
Tyler Scholl, Tyree H Kiser, Sheryl F Vondracek
Background: Chronic obstructive pulmonary disease (COPD) and pneumonia are leading causes of morbidity and mortality and are frequently comorbid. Studies of systemic corticosteroids in pneumonia have shown conflicting outcomes, whereas studies in acute exacerbations of COPD (AECOPD) have shown significant benefits. No studies have evaluated systemic corticosteroids in patients with both an AECOPD and pneumonia. Purpose: To evaluate the use of systemic corticosteroids in patients with both an AECOPD and pneumonia...
January 24, 2018: Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation
https://www.readbyqxmd.com/read/29629399/pneumonia-complicating-copd-are-corticosteroids-a-help-or-a-hindrance
#16
Michael S Niederman
No abstract text is available yet for this article.
January 18, 2018: Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation
https://www.readbyqxmd.com/read/29610118/beh%C3%A3-et-s-disease-pulmonary-aneurysm-resolution-with-oral-therapy-and-hla-b72-allele-association
#17
Clarissa de Albuquerque Botura, Luiz Eduardo Bersani-Amado, Antônio Rubens Zacarias-Júnior, Sueli Donizete Boreli, Naiene Gomes Gordo Stecca, Bruno Ambrósio da Rocha, Roberto Kenji Nakamura Cuman, Ciomar Aparecida Bersani-Amado
We report the case of a female patient who was diagnosed with a pulmonary artery aneurysm that was caused by Behçet's disease. The patient was initially diagnosed with community-acquired pneumonia and then pulmonary thromboembolism and aneurysm of the right pulmonary artery segmental branch was confirmed. The initial treatment consisted of anticoagulant drugs. After analysis of the family history and a positive pathergy test, the patient was diagnosed with Behçet's disease. Oral pharmacological treatment began with corticosteroids, cyclophosphamide, and anticoagulant suspension...
April 2, 2018: Clinical Medicine & Research
https://www.readbyqxmd.com/read/29594456/combined-pharmacotherapy-for-osteonecrosis-of-the-femoral-head-after-severe-acute-respiratory-syndrome-and-interstitial-pneumonia-two-and-a-half-to-fourteen-year-follow-up
#18
Weiguo Wang, Nianfei Zhang, Wanshou Guo, Fuqiang Gao
PURPOSE: The purpose of this study was to retrospectively analyze the clinical, functional, and radiological outcomes of combined pharmacotherapy to ONFH after high-dose corticosteroid therapy. METHOD: From August 2003 to June 2015, five patients (ten hips) of ONFH in ARCO stage I, after SARS and Interstitial pneumonia, were treated by combined pharmacotherapy. Lipo-prostaglandin E1 10 μg iv Bid × 28 days, enoxaparin 6000 iu H QD × 12 weeks, alendronate sodium tablet 10 mg QD × 1 year...
March 28, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29593187/a-case-of-interstitial-pneumonia-associated-with-anti-pl-7-antibody-in-a-patient-with-rheumatoid-arthritis
#19
Hiroyuki Kozai, Yuko Toyoda, Hisatsugu Goto, Jun Kishi, Makoto Tobiume, Yuya Yamashita, Haruka Nishimura, Mayo Kondo, Hiroshi Kawano, Yasuhiko Nishioka
A 65-year-old female had been treated rheumatoid arthritis (RA), interstitial pneumonia (IP) and nephrotic syndrome with prednisolone and cyclosporine. She was emergently admitted to our hospital due to the worsening exertional dyspnea and severe hypoxemia. Chest computed tomography (CT) showed new diffuse ground-glass opacities (GGOs) with slight consolidations along with bronchovascular bundle were observed in addition to pre-existing reticular shadows in both lungs with lower lobe-predominance. An acute exacerbation (AE) of pre-existing IP triggered by an infection was suspected, and the treatment with antibiotics and corticosteroid pulse therapy improved her general condition and chest radiological findings...
2018: Journal of Medical Investigation: JMI
https://www.readbyqxmd.com/read/29574888/corticosteroid-therapy-in-pneumonia-from-swine-origin-influenza-a-h1n1-in-china
#20
Yanyun Jia, Yifang Liao, Lu Shao, Lulu Du, Bo Wang, Dongju Su
Background The first three cases of confirmed infection with the virus in China were documented between May 10 and May 15, 2009. Although the clinical characteristics of the H1N1 pneumonia were described in clinical reports, the therapy has few been described. Therefore, we report our experiences of 53 cases of the H1N1 pneumonia with treatment. Methods We describe clinical characteristic of 53 patients who were hospitalized for laboratory-confirmed H1N1 pneumonia at the 2nd Clinical College of Harbin Medical University...
March 25, 2018: Journal of Medical Virology
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