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allograft augmentation

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https://www.readbyqxmd.com/read/28706848/bipolar-bone-loss-of-the-shoulder-joint-due-to-recurrent-instability-use-of-fresh-osteochondral-distal-tibia-and-humeral-head-allografts
#1
Daniel B Haber, Anthony Sanchez, George Sanchez, Marcio B Ferrari, Sami Ferdousian, Matthew T Provencher
With increasing shoulder instability events, the likelihood of a bony lesion of the glenoid and/or humeral head rises. Although bone loss of either the glenoid or humeral head may result in recurrent instability, bipolar lesions have been shown, in particular, to result in a negative and additive effect on glenohumeral stability. In the case of a bipolar lesion comprising severe glenoid bone loss and an engaging, "off-track" Hill-Sachs lesion, the bony foundation of the glenohumeral joint is compromised and bony augmentation is necessary...
June 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28706796/arthroscopic-removal-of-a-loose-polyethylene-glenoid-component-with-bone-grafting-and-patch-augmentation-for-glenoid-osseous-defect
#2
Jeffrey T Abildgaard, Jared C Bentley, Richard J Hawkins, John M Tokish
Glenoid component loosening is a common cause of failed total shoulder arthroplasty. Many different treatment options exist for the management of a symptomatic loose polyethylene glenoid component, ranging from component removal to revision arthroplasty. Arthroscopic removal and conversion to hemiarthroplasty provides a minimally invasive management option that avoids takedown of the subscapularis and allows for humeral prosthesis retention. Frequently, however, osteolysis is encountered concomitantly leading to cavitary glenoid bone deficits at the time of glenoid implant removal, limiting both immediate and future treatment options...
June 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28706180/serum-uric-acid-and-arterial-function-after-renal-transplantation
#3
Frederic Bauer, Nikolaos Pagonas, Felix S Seibert, Walter Zidek, Richard Viebahn, Nina Babel, Timm H Westhoff
BACKGROUND Hyperuricemia is associated with an increased risk of cardiovascular disease and chronic allograft nephropathy after renal transplantation. It has recently been demonstrated that treatment of asymptomatic hyperuricemia is associated with improved patient and graft survival; although, the underlying mechanisms remain elusive. The present study investigated the association of serum uric acid (SUA) and systemic arterial function after renal transplantation. MATERIAL AND METHODS In a cross-sectional study, arterial function was analyzed in 54 renal transplant recipients by means of pulse wave analysis...
July 14, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28686641/the-prognostic-importance-of-cxcr3-chemokine-during-organizing-pneumonia-on-the-risk-of-chronic-lung-allograft-dysfunction-after-lung-transplantation
#4
Michael Y Shino, S Samuel Weigt, Ning Li, Vyacheslav Palchevskiy, Ariss Derhovanessian, Rajan Saggar, David M Sayah, Richard H Huynh, Aric L Gregson, Michael C Fishbein, Abbas Ardehali, David J Ross, Joseph P Lynch, Robert M Elashoff, John A Belperio
RATIONALE: Since the pathogenesis of chronic lung allograft dysfunction (CLAD) remains poorly defined with no known effective therapies, the identification and study of key events which increase CLAD risk is a critical step towards improving outcomes. We hypothesized that bronchoalveolar lavage fluid (BALF) CXCR3 ligand concentrations would be augmented during organizing pneumonia (OP) and that episodes of OP with marked chemokine elevations would be associated with significantly higher CLAD risk...
2017: PloS One
https://www.readbyqxmd.com/read/28672142/how-effective-is-the-tent-screw-pole-technique-compared-to-other-forms-of-horizontal-ridge-augmentation
#5
George R Deeb, Dan Tran, Caroline K Carrico, Erin Block, Daniel M Laskin, Janina Golob Deeb
PURPOSE: The tent screw pole technique is one of the methods available for practitioners to perform horizontal ridge augmentation to facilitate dental implant placement. The purpose of this study was to evaluate the efficacy of the tent screw pole technique for horizontal ridge augmentation and to compare the results with those of the tunnel technique and open ridge augmentation. PATIENTS AND METHODS: In this retrospective cohort study, 35 patients underwent horizontal ridge augmentation with the tent screw pole technique, a 1:1 ratio of mineralized freeze-dried bone allograft and particulate bovine hydroxyapatite, and a resorbable collagen membrane...
June 13, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28663406/intercalary-allograft-augmented-with-intramedullary-cement-and-plate-fixation-is-a-reliable-solution-after-resection-of-a-diaphyseal-tumour
#6
S Gupta, L A Kafchinski, K R Gundle, K Saidi, A M Griffin, J S Wunder, P C Ferguson
AIMS: Intercalary allografts following resection of a primary diaphyseal tumour have high rates of complications and failures. At our institution intercalary allografts are augmented with intramedullary cement and fixed using compression plating. Our aim was to evaluate their long-term outcomes. PATIENTS AND METHODS: A total of 46 patients underwent reconstruction with an intercalary allograft between 1989 and 2014. The patients had a mean age of 32.8 years (14 to 77)...
July 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28662954/structural-allograft-supporting-a-trabecular-metal-cup-provides-durable-results-in-complex-revision-arthroplasty
#7
Hernan A Prieto, Michael E Kralovec, Daniel J Berry, Robert T Trousdale, Rafael J Sierra, Miguel E Cabanela
BACKGROUND: Revision total hip arthroplasty (THA) is challenging specially in the presence of severe acetabular bone deficiency. We report the use of a highly porous revision shell augmented by structural allograft to provide structural support and coverage to the acetabular component. METHODS: We identified 56 patients (58 hips) undergoing revision THA, where a trabecular metal revision cup was supported by structural allograft. Mean follow-up was 5.4 years (range 2-12 years)...
June 8, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28660143/distal-triceps-injuries-including-snapping-triceps-a-systematic-review-of-the-literature
#8
Kimberley Shuttlewood, James Beazley, Christopher D Smith
AIM: To review current literature on types of distal triceps injury and determine diagnosis and appropriate management. METHODS: We performed a systematic review in PubMed, Cochrane and EMBASE using the terms distal triceps tears and snapping triceps on the 10(th) January 2017. We excluded all animal, review, foreign language and repeat papers. We reviewed all papers for relevance and of the papers left we were able to establish the types of distal triceps injury, how these injuries are diagnosed and investigated and the types of management of these injuries including surgical...
June 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28657571/management-of-metaphyseal-bone-loss-in-revision-knee-arthroplasty
#9
Francesco Mancuso, Arianna Beltrame, Elia Colombo, Enrick Miani, Fabrizio Bassini
BACKGROUND AND AIM OF THE WORK: Revision total knee arthroplasty (TKA) is usually made more complex by the presence of bone defects, which may be caused by periprosthethic infection, polyethylene wear, implant loosening or fractures. The main aim of the present work is to review the available literature to understand the current options to manage with the bone loss during knee revisions. METHODS: Available English literature for bone defects in revision TKAs has been evaluated looking at treatment options and their results in terms of clinical and radiological outcomes and failure rates...
June 7, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28620645/alloimmunity-but-not-viral-immunity-promotes-allograft-loss-in-a-mouse-model-of-polyomavirus-associated-allograft-injury
#10
Steven C Kim, Jun Wang, Ying Dong, David V Mathews, Joshua A Albrecht, Cynthia P Breeden, Alton B Farris, Aron E Lukacher, Mandy L Ford, Kenneth A Newell, Andrew B Adams
BACKGROUND: The interplay between viral infection and alloimmunity is known to influence the fate of transplanted organs. Clarifying how local virus-associated inflammation/injury and antiviral immunity can alter host alloimmune responses in transplantation remains a critical question. METHODS: We used a mouse model of polyomavirus (PyV) infection and kidney transplantation to investigate the roles of direct viral pathology, the antiviral immune response, and alloimmunity in the pathogenesis of PyV-associated allograft injury...
June 2017: Transplantation Direct
https://www.readbyqxmd.com/read/28592072/-effects-of-trabecular-metal-augments-for-the-reconstruction-of-paprosky-type-%C3%A2-acetabulum-bone-defects
#11
Y Q Du, Y G Zhou, S Piao, W M Wu, H Y Ma, Z S Gao, J Y Sun, C Zheng, S Wang
Objective: To investigate the methods and short-time clinical results of reconstruction of Paprosky type Ⅲ acetabulum bone defects by using tantalum augments. Methods: A total of 17 patients (17 hips) with Paprosky type Ⅲ acetabulum bone defects, treated with tantalum augments in revision of total hip arthroplasty at Department of Orthopedics Surgery in General Hospital of Chinese People's Liberation Army were retrospectively analyzed from March 2014 to May 2016.There were 6 males and 11 females aged from 23 to 74 years with an average of (50...
June 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28583058/bone-grafts-substitutes-and-augments-in-benign-orthopaedic-conditions-current-concepts
#12
Alan Blank, Aldo Riesgo, Steven Gitelis, Timothy Rapp
Musculoskeletal tumors are relatively rare diagnoses made by orthopaedic surgeons. While approximately 2,500 primary bone sarcomas are diagnosed annually in the USA, the number of benign orthopaedic tumors encountered annually is far more difficult to quantify. Some studies have documented between 3% and 10% of the general population having benign bony lesions. Many of these conditions can be simply observed, while others will require surgical intervention. Surgical treatments for benign conditions range from a one-step curettage to extensive resection and reconstruction...
April 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28580270/anatomical-glenoid-reconstruction-using-fresh-osteochondral-distal-tibia-allograft-after-failed-latarjet-procedure
#13
Anthony Sanchez, Marcio B Ferrari, Ramesses A Akamefula, Rachel M Frank, George Sanchez, Matthew T Provencher
In the treatment of recurrent anterior glenohumeral instability, the Latarjet procedure has been shown to fail. This results in a need for viable revisional procedures for patients who present with this challenging pathology. We report our preferred technique for anatomical glenoid reconstruction using a fresh osteochondral distal tibia allograft after a failed Latarjet procedure. This bony augmentation technique employs a readily available dense, weight-bearing osseous tissue source that has excellent conformity, as well as the added benefit of a cartilaginous surface to correct chondral deficiencies...
April 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28580252/arthroscopic-hip-labral-augmentation-technique-with-iliotibial-band-graft
#14
Renato Locks, Jorge Chahla, Jonathan M Frank, Jack Anavian, Jonathan A Godin, Marc J Philippon
The importance of the acetabular labrum has been well documented for the function and overall health of the hip joint. Several biomechanical studies have shown the sealing effect of the acetabular labrum. In the past decade, labral repair procedures have gained increased attention, with the literature suggesting that the outcomes after hip arthroscopy are directly related to labral preservation. However, a primary labral repair can be challenging in cases of hypoplastic, ossified, or complex and irreparable labral tears in which there is insufficient tissue to perform a primary repair...
April 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28577709/microfracture-and-microfracture-plus
#15
REVIEW
Jay C Albright, Ariel Kiyomi Daoud
Articular cartilage damage remains a significant cause for early osteoarthritis in adolescents and young adults. After chondroplasty alone, the mainstay procedure for cartilage injuries is microfracture. Although in small lesions this may be successful long-term, positive results of treating larger lesions this way are less certain. This inconsistency in outcomes has led to augmentation of these defects with scaffolding for autograft regeneration or for allograft cartilage to fill the defect with a hyaline cartilage...
July 2017: Clinics in Sports Medicine
https://www.readbyqxmd.com/read/28570252/the-comparative-effectiveness-of-a-human-fibroblast-dermal-substitute-versus-a-dehydrated-human-amnion-chorion-membrane-allograft-for-the-treatment-of-diabetic-foot-ulcers-in-a-real-world-setting
#16
Ira Kraus, Michael L Sabolinski, Michelle Skornicki, Nathan B Parsons
BACKGROUND: Impaired wound healing is associated with serious complications in patients with diabetes. Diabetic foot ulcers (DFUs) can lead to costly complications and an increased mortality rate. Standard treatments for DFUs often need to be augmented with adjunctive therapies designed to stimulate healing in recalcitrant wounds. OBJECTIVE: This analysis was conducted to evaluate the comparative effectiveness of a human broblast-derived dermal substitute (HFDS) and a dehydrated human amnion/chorion membrane allograft (dHACM) for the treatment of DFUs...
May 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28569748/the-critical-role-of-senp1-mediated-gata2-desumoylation-in-promoting-endothelial-activation-in-graft-arteriosclerosis
#17
Cong Qiu, Yuewen Wang, Haige Zhao, Lingfeng Qin, Yanna Shi, Xiaolong Zhu, Lin Song, Xiaofei Zhou, Jian Chen, Hong Zhou, Haifeng Zhang, George Tellides, Wang Min, Luyang Yu
Data from clinical research and our previous study have suggested the potential involvement of SENP1, the major protease of post-translational SUMOylation, in cardiovascular disorders. Here, we investigate the role of SENP1-mediated SUMOylation in graft arteriosclerosis (GA), the major cause of allograft failure. We observe an endothelial-specific induction of SENP1 and GATA2 in clinical graft rejection specimens that show endothelial activation-mediated vascular remodelling. In mouse aorta transplantation GA models, endothelial-specific SENP1 knockout grafts demonstrate limited neointima formation with attenuated leukocyte recruitment, resulting from diminished induction of adhesion molecules in the graft endothelium due to increased GATA2 SUMOylation...
June 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/28556542/long-term-outcomes-of-de-novo-autoimmune-hepatitis-in-pediatric-liver-transplant-recipients
#18
Udeme D Ekong, Patrick McKiernan, Mercedes Martinez, Steven Lobritto, Deirdre Kelly, Vicky L Ng, Estella M Alonso, Yaron Avitzur
The long-term course and outcome of DAIH is unknown. A retrospective multicenter study assessing associations and long-term consequences of DAIH developing in a transplanted allograft is presented. Children with DAIH were followed from diagnosis until death, re-LT, or transfer of care and for a minimum of 1 year. A total of 31 patients of 1833 (1.7%) LT were identified; 29 followed for a median of 7.1 years (range, 1.6-15); 52% had no rejection preceding diagnosis of DAIH. Transaminases fell following treatment with steroids and antimetabolites (ALT 108 vs 39 U/L (P=...
May 29, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28548887/effects-of-bone-morphogenetic-protein-2-on-vertical-bone-augmentation-in-a-canine-model
#19
Yung-Ting Hsu, Khalid Al-Hezaimi, Pablo Galindo-Moreno, Francisco O'Valle, Abdulaziz Al-Rasheed, Hom-Lay Wang
BACKGROUND: Vertical bone augmentation (VBA) remains unpredictable and challenging for most clinicians. This study was aimed to compare hard tissue outcomes of VBA, with and without rhBMP-2, under space-making titanium mesh in a canine model. METHODS: Eleven male beagle dogs were used in the study. Experimental ridge defects were created to form atrophic ridges. VBA was performed via guide bone regeneration (GBR) using titanium mesh and allografts. In experimental hemimandibles, rhBMP-2/ACS was well mixed with allografts prior to procedures, whereas a control buffer was applied within controls...
May 26, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28507978/modified-tension-slide-technique-for-anatomical-distal-biceps-tenodesis-using-a-bicortical-endobutton-and-a-tenodesis-screw
#20
Jagadish Prabhu, Mohammed Khalid Faqi, Fahad Al-Khalifa, Rashad Khamis Awad
INTRODUCTION: Many surgical techniques have been described in the literature. In this article, we describe surgical technical details along with tips and tricks of distal biceps tendon tenodesis using the EndoButton and tension - slide technique, a modification of the suspensory cortical button technique, which allows the surgeon to tension and repairs the biceps tendon through the single longitudinal anterior incision. This modification in surgical technique of using dual implants, i...
November 2016: Journal of Orthopaedic Case Reports
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