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allograft augmentation

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https://www.readbyqxmd.com/read/28444407/-aseptic-loosening-of-total-ankle-replacement-and-conversion-to-ankle-arthrodesis
#1
M D Wimmer, M Hettchen, M M Ploeger, B Hintermann, D C Wirtz, A Barg
OBJECTIVE: To remove loosened prosthesis components, to perform augmentation, to address osseous defects, to perform neutrally aligned ankle arthrodesis, and to achieve postoperative pain relief. INDICATIONS: Symptomatic, aseptic loosening of total ankle replacement (TAR) with/without substantial bone defect of the tibial and/or talar bone stock. CONTRAINDICATIONS: General surgical or anesthesiological risks, periprosthetic infection, local or systemic infection, nonmanageable soft tissue problems...
April 25, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28428609/socket-preservation
#2
L Fee
Socket preservation maintains bone volume post-extraction in anticipation of an implant placement or fixed partial denture pontic site. This procedure helps compensate for the resorption of the facial bone wall. Socket preservation should be considered when implant placement needs to be delayed for patient or site-related reasons. The ideal healing time before implant placement is six months. Socket preservation can reduce the need for later bone augmentation. By reducing bone resorption and accelerating bone formation it increases implant success and survival...
April 21, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28419811/augmentation-of-distal-biceps-repair-with-an-acellular-dermal-graft-restores-native-biomechanical-properties-in-a-tendon-deficient-model
#3
Christine Conroy, Paul Sethi, Craig Macken, David Wei, Marc Kowalsky, Raffy Mirzayan, Leo Pauzenberger, Felix Dyrna, Elifho Obopilwe, Augustus D Mazzocca
BACKGROUND: The majority of distal biceps tendon injuries can be repaired in a single procedure. In contrast, complete chronic tears with severe tendon substance deficiency and retraction often require tendon graft augmentation. In cases with extensive partial tears of the distal biceps, a human dermal allograft may be used as an alternative to restore tendon thickness and biomechanical integrity. HYPOTHESIS: Dermal graft augmentation will improve load to failure compared with nonaugmented repair in a tendon-deficient model...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28406878/bone-loss-in-revision-total-knee-arthroplasty-evaluation-and-management
#4
Neil P Sheth, Marcelo Batista Bonadio, Marco Kawamura Demange
With the increasing number of total knee arthroplasty (TKA) procedures being performed annually, the burden of revision surgery is also expected to increase. Addressing bone loss during revision TKA is a considerable challenge that requires proper preoperative evaluation and surgical planning. In addition to an assessment of femoral and tibial bone loss, a systematic approach to the management of bone loss associated with TKA includes careful implant selection, adherence to the general principles of revision TKA, and an understanding of the available reconstruction options...
May 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28402343/use-of-allograft-with-platelet-concentrate-in-the-treatment-of-multiple-miller-class-iii-gingival-recession-defects-report-of-three-cases
#5
Yumi Ogata, Minh Bui, Terrence J Griffin, Yong Hur
Three patients with multiple Miller Class III recession defects with substantial bone loss were treated with hard tissue augmentation with the goal to prevent future recessions. The surgery involved a full-thickness mucoperiosteal coronally advanced flap, bone grafting, and primary flap closure. Freeze-dried bone allograft (FDBA) in combination with plasma rich in growth factors (PRGF) was grafted during the procedure. After more than 6 months, the treated sites showed soft tissue maturation and esthetic tissue blending...
May 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28394814/percutaneous-mechanical-circulatory-support-using-impella%C3%A2-devices-for-decompensated-cardiogenic-shock-a-pediatric-heart-center-experience
#6
Dhaval Parekh, Aamir Jeewa, Sebastian C Tume, William J Dreyer, Ricardo Pignatelli, David Horne, Henri Justino, Athar M Qureshi
Cardiogenic shock remains a significant cause of mortality and morbidity in children with heart failure. Percutaneous mechanical circulatory support may be an additional tool to augment left heart support and decompression in addition to conventional therapies. This report aims to review the clinical and hemodynamic outcomes of the Impella® device at a pediatric center. A retrospective review of all implants between October 2014 and November 2016 was conducted. Clinical outcomes, device implant techniques, complications, and hemodynamic data were collected...
April 6, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28375571/hla-mismatching-favoring-host-versus-graft-nk-cell-activity-via-kir3dl1-is-associated-with-improved-outcomes-following-lung-transplantation
#7
John R Greenland, Haibo Sun, Daniel Calabrese, Tiffany Chong, Jonathan P Singer, Jasleen Kukreja, Steven R Hays, Jeffrey A Golden, George H Caughey, Jeffrey M Venstrom, Raja Rajalinginam
Chronic lung allograft dysfunction (CLAD) is linked to rejection and limits survival following lung transplantation. HLA-Bw4 recipients of HLA-Bw6 grafts have enhanced host-versus-graft (HVG) NK cell activity mediated by KIR3DL1 ligand. Because natural killer (NK) cells may promote tolerance by depleting antigen-presenting cells, we hypothesized improved outcomes for HLA-Bw4 recipients of HLA-Bw6 grafts. We evaluated differences in acute cellular rejection (ACR) and CLAD-free survival across 252 KIR3DL1+ recipients from UCSF...
April 4, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28332167/controlled-release-of-vanadium-from-a-composite-scaffold-stimulates-mesenchymal-stem-cell-osteochondrogenesis
#8
S D Schussler, K Uske, P Marwah, F W Kemp, J D Bogden, S S Lin, Treena Livingston Arinzeh
Large bone defects often require the use of autograft, allograft, or synthetic bone graft augmentation; however, these treatments can result in delayed osseous integration. A tissue engineering strategy would be the use of a scaffold that could promote the normal fracture healing process of endochondral ossification, where an intermediate cartilage phase is later transformed to bone. This study investigated vanadyl acetylacetonate (VAC), an insulin mimetic, combined with a fibrous composite scaffold, consisting of polycaprolactone with nanoparticles of hydroxyapatite and beta-tricalcium phosphate, as a potential bone tissue engineering scaffold...
March 22, 2017: AAPS Journal
https://www.readbyqxmd.com/read/28326892/clinical-and-histomorphometric-assessment-of-lateral-alveolar-ridge-augmentation-using-a-corticocancellous-freeze-dried-allograft-bone-block
#9
Roya Shariatmadar Ahmadi, Ferena Sayar, Vahid Rakhshan, Babak Iranpour, Jahanfar Jahanbani, Ahmad Toumaj, Nasrin Akhoondi
Horizontal ridge augmentation with allografts has attracted notable attention because of its proper success rate and the lack of disadvantages of autografts. Corticocancellous block allografts have not been adequately studied on humans. Therefore, this study evaluated clinically and histomorphometrically the increase in ridge with after horizontal ridge augmentation using corticocancellous block allografts, and the implant success after 12 to 18 months post-implantation. In 10 implant patients (3 women, 7 men, 45 years old on average), defective maxillary alveolar ridges were horizontally augmented using freeze-dried bone allograft blocks...
March 22, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28302753/erythropoietin-receptor-mediated-molecular-crosstalk-promotes-t-cell-immunoregulation-and-transplant-survival
#10
Carolina Purroy, Robert L Fairchild, Toshiaki Tanaka, William M Baldwin, Joaquin Manrique, Joren C Madsen, Robert B Colvin, Alessandro Alessandrini, Bruce R Blazar, Miguel Fribourg, Chiara Donadei, Umberto Maggiore, Peter S Heeger, Paolo Cravedi
Although spontaneous kidney transplant acceptance/tolerance occurs in mice and occasionally in humans, mechanisms remain unclear. Herein we test the hypothesis that EPO, a hormone predominantly produced by the adult kidney, has immunomodulating properties that are required for spontaneous kidney graft acceptance. In vitro, in a manner dependent on the EPO receptor and CD131 on antigen-presenting cells, EPO induced the secretion of active TGFβ by antigen-presenting cells, which in turn converted naïve CD4(+) T cells into functional Foxp3(+) regulatory T cells (Treg)...
March 16, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28298833/minimally-invasive-maxillary-sinus-elevation-using-balloon-system-a-case-series
#11
Radha Bharathi Dhandapani, Shivakumar Baskaran, Kurumathur Vasudevan Arun, Thirunelveli Saravanan Subbu Kumar
The posterior maxillary segment frequently exhibits insufficient bone mass to support dental implants. Sinus floor augmentation enables implant placement in the posterior maxilla. This case series included ten sites, in which sinus floor elevation was done using sinus lift balloon system followed by augmentation utilizing irradiated cancellous bone allograft. Postoperative radiographic assessment of vertical bone gain was done at 3 and 6 months follow-up period. The mean initial and final bone height were 6...
July 2016: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/28298052/allograft-augmentation-of-hamstring-autograft-for-younger-patients-undergoing-anterior-cruciate-ligament-reconstruction
#12
Cale A Jacobs, Jeremy M Burnham, Eric Makhni, Chaitu S Malempati, Eric Swart, Darren L Johnson
BACKGROUND: Younger patients and those with smaller hamstring autograft diameters have been shown to be at significantly greater risk of graft failure after anterior cruciate ligament (ACL) reconstruction. To date, there is no information in the literature about the clinical success and/or cost-effectiveness of increasing graft diameter by augmenting with semitendinosus allograft tissue for younger patients. HYPOTHESIS: Hybrid hamstring grafts are a cost-effective treatment option because of a reduced rate of graft failure...
March 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28296000/novel-application-of-localized-nanodelivery-of-anti-interleukin-6-protects-organ-transplant-from-ischemia-reperfusion-injuries
#13
Z Solhjou, M Uehara, B Bahmani, O H Maarouf, T Ichimura, C R Brooks, W Xu, M Yilmaz, A Elkhal, S G Tullius, I Guleria, M M McGrath, R Abdi
Ischemia-reperfusion injury (IRI) evokes intragraft inflammatory responses, which markedly augment alloimmune responses against the graft. Understanding the mechanisms underlying these responses is fundamental to develop therapeutic regimens to prevent/ameliorate organ IRI. Here, we demonstrate that IRI results in a marked increase in mitochondrial damage and autophagy in dendritic cells (DCs). While autophagy is a survival mechanism for ischemic DCs, it also augments their production of interleukin (IL)-6...
March 12, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28281138/corr-%C3%A2-tumor-board-is-there-benefit-to-free-over-pedicled-vascularized-grafts-in-augmenting-tibial-intercalary-allograft-constructs
#14
Megan E Anderson, Jim S Wu, Sara O Vargas
No abstract text is available yet for this article.
May 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28280894/clinical-outcomes-in-breast-reconstruction-patients-using-a-sterile-acellular-dermal-matrix-allograft
#15
Juan A Ortiz
BACKGROUND: Human acellular dermal matrices (ADMs) have enabled successful breast reconstructions while decreasing muscle donor morbidity and pain for the patient. However, some literature reports indicate an increase in complications, especially infection. The decellularization and terminal sterilization properties of DermACELL (D-ADM), a human ADM, may reduce the rate of complications in augmented breast reconstruction while still maintaining successful outcomes. In the study presented here, we evaluate the quality and safety of outcomes with the use of D-ADM during tissue expander breast reconstruction...
March 9, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28255289/an-update-on-lower-lid-blepharoplasty
#16
REVIEW
Michael Murri, Eric B Hamill, Matthew J Hauck, Douglas P Marx
Aging changes to the lower eyelids and midface include pseudoherniated orbital fat, tear trough deformity, lid laxity, and dermatochalasis. Surgical repair often aims at treating redundant skin or orbital fat malposition with a lower eyelid blepharoplasty. Either a transcutaneous or transconjunctival approach may be used, though recent trends have favored the transconjunctival technique if procedures require more than simple skin excision. In manipulating the inferior orbital fat pads, a surgeon has many options including excision, repositioning, or augmentation with synthetic dermal filler, autologous fat grafts, or acellular dermal allografts...
February 2017: Seminars in Plastic Surgery
https://www.readbyqxmd.com/read/28224069/allograft-anterior-cruciate-ligament-reconstruction-utilizing-internal-brace-augmentation
#17
Patrick A Smith, Jordan A Bley
Anterior cruciate ligament (ACL) tears are among the most common sports-related injuries. Although studies have reported reliable outcomes with allograft tissue, several studies have shown a higher failure rate in younger patients. Although ACL graft augmentation has been met with varying levels of success, internal bracing of an allograft represents a promising area in ACL reconstruction. The purpose of this article is to detail allograft preparation involving a collagen-coated, ultrahigh-molecular-weight polyethylene/polyester suture tape as an internal brace augmentation for ACL reconstruction using the all-inside ACL GraftLink Technique (Arthrex, Naples, FL)...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28208056/oral-rehabilitation-of-a-patient-with-ectodermal-dysplasia-treated-with-fresh-frozen-bone-allografts-and-computer-guided-implant-placement-a-clinical-case-report
#18
Carlo Maiorana, Pier Paolo Poli, Carlo Poggio, Paola Barbieri, Mario Beretta
Ectodermal dysplasia (ED) is an inherited disorder characterized by abnormality of ectodermally derived structures. A recurrent oral finding is oligodontia, which in turn leads to a severely hypotrophic alveolar process with typical knife-edge morphology and adverse ridge contours. This unfavorable anatomy can seriously hamper proper implant placement. Fresh-frozen bone (FFB) allografts recently have been proposed to augment the residual bone volume for implant placement purposes; however, scientific evidence concerning the use of FFB to treat ED patients is absent...
January 20, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28194290/latissimus-dorsi-tendon-transfer-with-graftjacket%C3%A2-augmentation-to-increase-tendon-length-for-an-irreparable-rotator-cuff-tear
#19
John G Skedros, Tanner R Henrie
Massive irreparable rotator cuff tears can be reconstructed with latissimus dorsi tendon transfers (LDTT). Although uncommon, the natural length of the latissimus dorsi tendon (LDT) could be insufficient for transfer even after adequate soft tissue releases. Descriptions of cases where grafts were needed to lengthen the LDT are therefore rare. We located only two reports of the use of an acellular dermal matrix to increase effective tendon length in tendon transfers about the shoulder: (1) GraftJacket patch for a pectoralis major tendon reconstruction and (2) ArthroFlex® patch for LDTT...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28185397/the-clinical-effectiveness-of-alveolar-ridge-preservation-in-the-maxillary-anterior-esthetic-zone-a-retrospective-study
#20
Albert Ming Hsien Lee, Choy Yoke Poon
PURPOSE: The primary aim was to investigate whether ridge preservation done at extraction will preserve at least 6 mm of alveolar ridge width in the anterior maxillary zone and obviate the need for secondary bone augmentation during implant insertion. METHODS: Sixty patients with single implants placed in the anterior maxillary zone were classified in two groups. In the test group, 40 patients underwent ridge preservation at the time of tooth extraction, while the remaining 20 patients in the control group did not...
April 2017: Journal of Esthetic and Restorative Dentistry
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