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https://www.readbyqxmd.com/read/27833693/e-cigarette-blast-injury-complex-facial-fractures-and-pneumocephalus
#1
Benjamin A Archambeau, Stephanie Young, Carol Lee, Troy Pennington, Christopher Vanderbeek, Dan Miulli, John Culhane, Michael Neeki
Electronic cigarettes (also known as e-cigarettes or e-cigs) are becoming a popular method of recreational nicotine use over recent years. The growth of new brands and devices has been outpacing the FDA's ability to regulate them. As a result, some of these devices fail without warning, most likely from malfunction of the lithium-ion batteries that are in close proximity to volatile compounds within the device. Failures have occurred during both use and storage of the devices or their components. The subsequent injuries from several of these events, including full thickness burns requiring grafting and blast injuries, have been observed at Arrowhead Regional Medical Center, a regional trauma and burn center in southern California...
November 2016: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27829296/development-and-characterization-of-electronic-cigarette-exposure-generation-system-ecig-egs-for-the-physico-chemical-and-toxicological-assessment-of-electronic-cigarette-emissions
#2
Jiayuan Zhao, Georgios Pyrgiotakis, Philip Demokritou
Electronic cigarettes (e-cig) have been introduced as a nicotine replacement therapy and have gained increasing attention and popularity. However, while findings on possible toxicological implications continue to grow, major knowledge gaps on both the complex chemistry of the exposure and toxicity exist, prohibiting public health assessors from assessing risks. Here, a versatile electronic cigarette exposure generation system (Ecig-EGS) has been developed and characterized. Ecig-EGS allows generation of real world e-cig emission profiles under controlled operational conditions, real time monitoring and time-integrated particle/gas sampling for physico-chemical characterization, and toxicological assessment (both in vitro and in vivo)...
November 10, 2016: Inhalation Toxicology
https://www.readbyqxmd.com/read/27810679/e-cigarettes-as-a-source-of-toxic-and-potentially-carcinogenic-metals
#3
Catherine Ann Hess, Pablo Olmedo, Ana Navas-Acien, Walter Goessler, Joanna E Cohen, Ana Maria Rule
BACKGROUND AND AIMS: The popularity of electronic cigarette devices is growing worldwide. The health impact of e-cigarette use, however, remains unclear. E-cigarettes are marketed as a safer alternative to cigarettes. The aim of this research was the characterization and quantification of toxic metal concentrations in five, nationally popular brands of cig-a-like e-cigarettes. METHODS: We analyzed the cartomizer liquid in 10 cartomizer refills for each of five brands by Inductively Coupled Plasma Mass Spectrometry (ICP-MS)...
January 2017: Environmental Research
https://www.readbyqxmd.com/read/27791204/e-cigarettes-and-flavorings-induce-inflammatory-and-pro-senescence-responses-in-oral-epithelial-cells-and-periodontal-fibroblasts
#4
Isaac K Sundar, Fawad Javed, Georgios E Romanos, Irfan Rahman
Electronic-cigarettes (e-cigs) represent a significant and increasing proportion of tobacco product consumption, which may pose an oral health concern. Oxidative/carbonyl stress via protein carbonylation is an important factor in causing inflammation and DNA damage. This results in stress-induced premature senescence (a state of irreversible growth arrest which re-enforces chronic inflammation) in gingival epithelium, which may contribute to the pathogenesis of oral diseases. We show that e-cigs with flavorings cause increased oxidative/carbonyl stress and inflammatory cytokine release in human periodontal ligament fibroblasts, Human Gingival Epithelium Progenitors pooled (HGEPp), and epigingival 3D epithelium...
October 24, 2016: Oncotarget
https://www.readbyqxmd.com/read/27738114/use-of-icsi-in-ivf-cycles-in-women-with-tubal-ligation-does-not-improve-pregnancy-or-live-birth-rates
#5
F W Grimstad, Ajay K Nangia, B Luke, J E Stern, W Mak
STUDY QUESTION: Does ICSI improve outcomes in ART cycles without male factor, specifically in couples with a history of tubal ligation as their infertility diagnosis? SUMMARY ANSWER: The use of ICSI showed no significant improvement in fertilization rate and resulted in lower pregnancy and live birth (LB) rates for women with the diagnosis of tubal ligation and no male factor. WHAT IS KNOWN ALREADY: Prior studies have suggested that ICSI use does not improve fertilization, pregnancy or LB rates in couples with non-male factor infertility...
October 13, 2016: Human Reproduction
https://www.readbyqxmd.com/read/27721496/development-validation-and-application-of-a-device-to-measure-e-cigarette-users-puffing-topography
#6
Anthony Cunningham, Sandra Slayford, Carl Vas, Jodie Gee, Sandra Costigan, Krishna Prasad
With the rapidly rising popularity and substantial evolution of electronic cigarettes (e-cigarettes) in the past 5-6 years, how these devices are used by vapers and consumers' exposure to aerosol emissions need to be understood. We used puffing topography to measure directly product use. We adapted a cigarette puffing topography device for use with e-cigarettes. We performed validation using air and e-cigarette aerosol under multiple regimes. Consumer puffing topography was measured for 60 vapers provided with rechargeable "cig-a-like" or larger button-activated e-cigarettes, to use ad-libitum in two sessions...
October 10, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27668320/patterns-of-youth-tobacco-and-polytobacco-usage-the-shift-to-alternative-tobacco-products
#7
Paul T Harrell, Syeda Mahrukh H Naqvi, Andrew D Plunk, Ming Ji, Silvia S Martins
BACKGROUND: Despite significant declines in youth cigarette smoking, overall tobacco usage remains over 20% as non-cigarette tobacco product usage is increasingly common and polytobacco use (using 1+ tobacco product) remains steady. OBJECTIVES: The present study was designed to identify patterns of youth tobacco use and examine associations with sociodemographic characteristics and tobacco dependence. METHODS: The current analysis uses Latent Class Analysis (LCA) to examine the 6,958 tobacco users (n = 2,738 female) in the National Youth Tobacco Survey (2012 and 2013)...
September 26, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27619553/prohibition-of-e-cigarettes-in-the-us-are-prohibitions-where-alcohol-is-consumed-related-to-lower-alcohol-consumption
#8
Alexandra R Hershberger, Kenny A Karyadi, Melissa A Cyders
Recently, research has suggested negative consequences related to electronic cigarette (e-cig) use, including the increased risk for alcohol use and abuse. Previous work found that cigarette smoking ban legislation lowered overall smoking and alcohol use rates; however, researchers have not yet examined the potential effects of prohibiting e-cig use. The present study surveyed 617 individuals from a community-based online sample in the US (mean age = 33.33, SD = 10.50, 54.7 per cent female) who reported their smoking/e-cig use status, alcohol consumption, and the presence of e-cig prohibitions where they consume alcohol...
September 12, 2016: Journal of Public Health Policy
https://www.readbyqxmd.com/read/27596227/should-electronic-cigarette-use-be-covered-by-clean-indoor-air-laws
#9
Jessica M Yingst, Susan Veldheer, Erin Hammett, Shari Hrabovsky, Jonathan Foulds
BACKGROUND: Some jurisdictions have passed legislation that bans electronic cigarette (e-cig) use (vaping) in public places similarly to smoking. Many other jurisdictions have not yet determined how to regulate vaping in public places. This study examined the proportion of current e-cig users who find their vaping restricted in public places and further evaluated factors associated with the differences between restricted and unrestricted vapers. METHODS: 3960 experienced exclusive e-cig users completed an online survey from December 2012 to May 2014 about their e-cig use...
September 5, 2016: Tobacco Control
https://www.readbyqxmd.com/read/27559692/monitoring-nicotine-intake-from-e-cigarettes-measurement-of-parent-drug-and-metabolites-in-oral-fluid-and-plasma
#10
Esther Papaseit, Magí Farré, Silvia Graziano, Roberta Pacifici, Clara Pérez-Mañá, Oscar García-Algar, Simona Pichini
BACKGROUND: Electronic cigarettes (e-cig) known as electronic nicotine devices recently gained popularity among smokers. Despite many studies investigating their safety and toxicity, few examined the delivery of e-cig-derived nicotine and its metabolites in alternative biological fluids. METHODS: We performed a randomized, crossover, and controlled clinical trial in nine healthy smokers. Nicotine (NIC), cotinine (COT), and trans-3'-hydroxycotinine (3-HCOT) were measured in plasma and oral fluid by liquid chromatography-tandem mass spectrometry after consumption of two consecutive e-cig administrations or two consecutive tobacco cigarettes...
August 25, 2016: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/27559149/differences-in-cumulus-cell-gene-expression-indicate-the-benefit-of-a-pre-maturation-step-to-improve-in-vitro-bovine-embryo-production
#11
Cecilia Dieci, Valentina Lodde, Rémi Labreque, Isabelle Dufort, Irene Tessaro, Marc-André Sirard, Alberto M Luciano
STUDY QUESTION: Does the gene expression profile of cumulus cells (CC) accompanying oocytes with different degrees of chromatin compaction within the germinal vesicle (GV) reflect the oocyte's quality and response in culture during in-vitro embryo production (IVP). SUMMARY ANSWER: The transcriptomic profile of the cumulus cells is related to oocyte competence, setting the stage for the development of customized pre-maturation strategies to improve IVP. WHAT IS KNOWN ALREADY: Oocytes complete the acquisition of their competence during antral follicle development...
August 24, 2016: Molecular Human Reproduction
https://www.readbyqxmd.com/read/27446984/online-e-cigarette-marketing-claims-a-systematic-content-and-legal-analysis
#12
Elizabeth G Klein, Micah Berman, Natalie Hemmerich, Cristen Carlson, SuSandi Htut, Michael Slater
OBJECTIVES: Electronic nicotine delivery systems (ENDS), or e-cigarettes, are heavily marketed online. The purpose of our study was to perform a systematic identification and evaluation of claims made within ENDS retailer and manufacturer websites, and the legal status of such claims. METHODS: We employed a systematic search protocol with popular search engines using 6 terms: (1) e-cigarettes; (2) e-cigs; (3) e-juice; (4) e-liquid; (5) e-hookah; and (6) vape pen...
July 2016: Tobacco Regulatory Science
https://www.readbyqxmd.com/read/27443017/e-cigs-could-reduce-deaths-from-cigarette-smoking
#13
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Community Practitioner: the Journal of the Community Practitioners' & Health Visitors' Association
https://www.readbyqxmd.com/read/27343559/electronic-cigarette-aerosols-and-copper-nanoparticles-induce-mitochondrial-stress-and-promote-dna-fragmentation-in-lung-fibroblasts
#14
Chad A Lerner, Pierrot Rutagarama, Tanveer Ahmad, Isaac K Sundar, Alison Elder, Irfan Rahman
Oxidants or nanoparticles have recently been identified as constituents of aerosols released from various styles of electronic cigarettes (E-cigs). Cells in the lung may be directly exposed to these constituents and harbor reactive properties capable of incurring acute cell injury. Our results show mitochondria are sensitive to both E-cig aerosols and aerosol containing copper nanoparticles when exposed to human lung fibroblasts (HFL-1) using an Air-Liquid Interface culture system, evident by elevated levels of mitochondrial ROS (mtROS)...
September 2, 2016: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27342543/health-professionals-in-flanders-perceive-the-potential-health-risks-of-vaping-as-lower-than-those-of-smoking-but-do-not-recommend-using-e-cigarettes-to-their-smoking-patients
#15
Dinska Van Gucht, Frank Baeyens
BACKGROUND: Many misperceptions of both risks and opportunities of e-cigarettes (e-cigs) exist among the general population and among physicians, although e-cigs could be a valuable harm reduction tool for current smokers. METHODS: Two groups in Flanders, namely general practitioners (GPs; family doctors) and tobacco counselors filled out an online questionnaire with regard to their attitudes and risk perceptions concerning e-cigs. Statements included were on the safety and the addictive properties of e-cigs in absolute terms, whereas other items compared e-cigs with regular tobacco cigarettes...
2016: Harm Reduction Journal
https://www.readbyqxmd.com/read/27184092/electronic-cigarette-exposure-triggers-neutrophil-inflammatory-responses
#16
Andrew Higham, Nicholas J W Rattray, Jennifer A Dewhurst, Drupad K Trivedi, Stephen J Fowler, Royston Goodacre, Dave Singh
BACKGROUND: The use of electronic cigarettes (e-cigs) is increasing and there is widespread perception that e-cigs are safe. E-cigs contain harmful chemicals; more research is needed to evaluate the safety of e-cig use. Our aim was to investigate the effects of e-cigs on the inflammatory response of human neutrophils. METHODS: Neutrophils were exposed to e-cig vapour extract (ECVE) and the expression of CD11b and CD66b was measured by flow cytometry and MMP-9 and CXCL8 by ELISA...
2016: Respiratory Research
https://www.readbyqxmd.com/read/27147418/reasons-for-using-electronic-cigarettes-and-intentions-to-quit-among-electronic-cigarette-users-in-malaysia
#17
Li Ping Wong, Sharina Mahavera Mohamad Shakir, Haridah Alias, Nasrin Aghamohammadi, Victor Cw Hoe
The rapidly increasing uptake of e-cigarettes in Malaysia as of late demands a study to identify factors leading to its increased popularity and user intentions to quit smoking e-cigarettes. A convenience sample of e-cigarette smokers visiting e-cigarette retail shops in Selangor and Kuala Lumpur was recruited. The majority of e-cigarette smokers were youth in colleges or universities (39 %), and young professionals and managers (36 %). The main reasons for using e-cigarettes were to help the user quit tobacco cigarettes (88 %), the perception that e-cigarettes are not as intrusive as tobacco cigarettes (85 %) and can be used in public areas (70 %), the perception that e-cigarettes are healthier than tobacco cigarettes (85 %), and its relatively lower cost compared to tobacco cigarettes (65 %)...
May 4, 2016: Journal of Community Health
https://www.readbyqxmd.com/read/27142201/the-potential-that-electronic-nicotine-delivery-systems-can-be-a-disruptive-technology-results-from-a-national-survey
#18
Terry F Pechacek, Pratibha Nayak, Kyle R Gregory, Scott R Weaver, Michael P Eriksen
INTRODUCTION: This study evaluates the reasons for use and acceptance of Electronic Nicotine Delivery Systems (ENDS) among current and former cigarette smokers to assess if ENDS may become a satisfying alternative to cigarettes. METHODS: Data are from a national probability sample of 5717 US adults, surveyed June-November 2014. The survey contained questions on awareness, usage, and reasons for use of traditional and novel tobacco products. The analytic sample was current and former smokers who ever used ENDS (n = 729) and was divided into four mutually exclusive categories...
October 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/27117495/a-framework-for-in-vitro-systems-toxicology-assessment-of-e-liquids
#19
Anita R Iskandar, Ignacio Gonzalez-Suarez, Shoaib Majeed, Diego Marescotti, Alain Sewer, Yang Xiang, Patrice Leroy, Emmanuel Guedj, Carole Mathis, Jean-Pierre Schaller, Patrick Vanscheeuwijck, Stefan Frentzel, Florian Martin, Nikolai V Ivanov, Manuel C Peitsch, Julia Hoeng
Various electronic nicotine delivery systems (ENDS), of which electronic cigarettes (e-cigs) are the most recognized prototype, have been quickly gaining ground on conventional cigarettes because they are perceived as less harmful. Research assessing the potential effects of ENDS exposure in humans is currently limited and inconclusive. New products are emerging with numerous variations in designs and performance parameters within and across brands. Acknowledging these challenges, we present here a proposed framework for an in vitro systems toxicology assessment of e-liquids and their aerosols, intended to complement the battery of assays for standard toxicity assessments...
July 2016: Toxicology Mechanisms and Methods
https://www.readbyqxmd.com/read/27096665/-not-available
#20
C A Pastore, J A Pinho, C Pinho, N Samesima, H G Pereira Filho, J C L Kruse, A Paixão, A R Pérez-Riera, A L Ribeiro, C A R Oliveira, C I G Gomes, E Kaiser, F Galvão, F C C Darrieux, F F A C França, G Feitosa Filho, H Germiniani, J L Aziz, M G Leal, M Molina, N M T Oliveira, P A Oliveira, P C R Sanches, R M Almeida, R Barbosa, R A Teixeira, R A G Douglas, R S Gundim, S M Atanes
No abstract text is available yet for this article.
April 2016: Arquivos Brasileiros de Cardiologia
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