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https://www.readbyqxmd.com/read/29187640/generative-models-for-network-neuroscience-prospects-and-promise
#1
REVIEW
Richard F Betzel, Danielle S Bassett
Network neuroscience is the emerging discipline concerned with investigating the complex patterns of interconnections found in neural systems, and identifying principles with which to understand them. Within this discipline, one particularly powerful approach is network generative modelling, in which wiring rules are algorithmically implemented to produce synthetic network architectures with the same properties as observed in empirical network data. Successful models can highlight the principles by which a network is organized and potentially uncover the mechanisms by which it grows and develops...
November 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29174674/knowledge-attitudes-and-practices-of-private-sector-immunization-service-providers-in-gujarat-india
#2
José E Hagan, Narayan Gaonkar, Vikas Doshi, Anas Patni, Shailee Vyas, Vihang Mazumdar, J K Kosambiya, Satish Gupta, Margaret Watkins
BACKGROUND: India is responsible for 30% of the annual global cohort of unvaccinated children worldwide. Private practitioners provide an estimated 21% of vaccinations in urban centers of India, and are important partners in achieving high vaccination coverage. METHODS: We used an in-person questionnaire and on-site observation to assess knowledge, attitudes, and practices of private immunization service providers regarding delivery of immunization services in the urban settings of Surat and Baroda, in Gujarat, India...
November 22, 2017: Vaccine
https://www.readbyqxmd.com/read/29113579/use-of-research-interfaces-for-psychophysical-studies-with-cochlear-implant-users
#3
Ruth Y Litovsky, Matthew J Goupell, Alan Kan, David M Landsberger
A growing number of laboratories are using research interfaces to conduct experiments with cochlear-implant (CI) users. Because these interfaces bypass a subject's clinical sound processor, several concerns exist regarding safety and stimulation levels. Here we suggest best-practice approaches for how to safely and ethically perform this type of research and highlight areas of limited knowledge where further research is needed to help clarify safety limits. The article is designed to provide an introductory level of technical detail about the devices and the effects of electrical stimulation on perception and neurophysiology...
January 2017: Trends in Hearing
https://www.readbyqxmd.com/read/29059461/should-we-treat-acute-hepatitis-c-a-decision-and-cost-effectiveness-analysis
#4
Emily Bethea, Qiushi Chen, Chin Hur, Raymond T Chung, Jagpreet Chhatwal
It is not standard practice to treat patients with acute hepatitis C virus (HCV) infection. However, as the incidence of HCV in the United States continues to rise, it may be time to re-evaluate acute HCV management in the era of direct-acting antiviral agents (DAAs). In this study a microsimulation model was developed to analyze the tradeoffs between initiating HCV therapy in the acute versus chronic phase of infection. By simulating the lifetime clinical course of patients with acute HCV infection, we were able to project long-term outcomes such as quality-adjusted life years (QALYs) and costs...
October 23, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28944730/optimization-of-medication-use-at-accountable-care-organizations
#5
Chrisanne Wilks, Erik Krisle, Kimberly Westrich, Kristina Lunner, David Muhlestein, Robert Dubois
BACKGROUND: Optimized medication use involves the effective use of medications for better outcomes, improved patient experience, and lower costs. Few studies systematically gather data on the actions accountable care organizations (ACOs) have taken to optimize medication use. OBJECTIVES: To (a) assess how ACOs optimize medication use; (b) establish an association between efforts to optimize medication use and achievement on financial and quality metrics; (c) identify organizational factors that correlate with optimized medication use; and (d) identify barriers to optimized medication use...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28922952/transitions-that-matter-life-course-differences-in-the-employment-of-adults-with-arthritis
#6
Arif Jetha, Julie Bowring, Sean Tucker, Catherine E Connelly, Kathleen A Martin Ginis, Laurie Proulx, Monique A M Gignac
PURPOSE: To understand the similarities and differences in the employment participation of people living with arthritis across the life course. METHOD: Focus groups and interviews were conducted with young (ages 18-34 years, n = 7), middle-aged (ages 35-54 years, n = 13) and older adults (>55 years, n = 25) with arthritis. Participants were asked about the impact of arthritis on employment, experiences with health-related changes, career progression and social role involvement...
September 18, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28905669/correction-notice
#7
(no author information available yet)
Agee, M. D., & Gates, Z. (2014). The Impact of an Insurance Administration-Free Primary Care Office on Hospital Admissions: A Community-Level Comparison With Traditional Fee-for-Service Family Practice Groups. Journal of Primary Care & Community Health, 5, 202-207. doi: 10.1177/2150131914522123 The following Conflict of Interest statement was originally omitted and will be added to the article: Author Zane Gates's affiliation, UPMC Altoona, is the parent organization of Partnering for Health Services. Additionally, author Zane Gates has an ownership interest in the Empower(3) Center for Health, a direct-pay primary care clinic using a subscription coverage model, that additionally provides insurance counseling and prescription programs...
September 1, 2017: Journal of Primary Care & Community Health
https://www.readbyqxmd.com/read/28885637/-is-there-an-app-for-that-orthopaedic-patient-preferences-for-a-smartphone-application
#8
Jonathan R Datillo, Daniel J Gittings, Matthew Sloan, William M Hardaker, Matthew J Deasey, Neil P Sheth
BACKGROUND: Patients are seeking out medical information on the Internet and utilizing smartphone health applications ("apps"). Smartphone use has exponentially increased among orthopaedic surgeons and patients. Despite this increase, patients are rarely directed to specific apps by physicians. No study exists querying patient preferences for a patient-centered, orthopaedic smartphone application. OBJECTIVES: The purpose of this study is to 1) determine Internet use patterns amongst orthopaedic patients; 2) ascertain access to and use of smartphones; and 3) elucidate what features orthopaedic patients find most important in a smartphone application...
August 16, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28857042/cost-and-outcome-of-behavioural-activation-cobra-a-randomised-controlled-trial-of-behavioural-activation-versus-cognitive-behavioural-therapy-for-depression
#9
David A Richards, Shelley Rhodes, David Ekers, Dean McMillan, Rod S Taylor, Sarah Byford, Barbara Barrett, Katie Finning, Poushali Ganguli, Fiona Warren, Paul Farrand, Simon Gilbody, Willem Kuyken, Heather O'Mahen, Ed Watkins, Kim Wright, Nigel Reed, Emily Fletcher, Steven D Hollon, Lucy Moore, Amy Backhouse, Claire Farrow, Julie Garry, Deborah Kemp, Faye Plummer, Faith Warner, Rebecca Woodhouse
BACKGROUND: Depression is a common, debilitating and costly disorder. The best-evidenced psychological therapy - cognitive-behavioural therapy (CBT) - is complex and costly. A simpler therapy, behavioural activation (BA), may be an effective alternative. OBJECTIVES: To determine the clinical effectiveness and cost-effectiveness of BA compared with CBT for depressed adults at 12 and 18 months' follow-up, and to investigate the processes of treatments. DESIGN: Randomised controlled, non-inferiority trial stratified by depression severity, antidepressant use and recruitment site, with embedded process evaluation; and randomisation by remote computer-generated allocation...
August 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28851401/knowledge-sharing-in-global-health-research-the-impact-uptake-and-cost-of-open-access-to-scholarly-literature
#10
Elise Smith, Stefanie Haustein, Philippe Mongeon, Fei Shu, Valéry Ridde, Vincent Larivière
BACKGROUND: In 1982, the Annals of Virology published a paper showing how Liberia has a highly endemic potential of Ebola warning health authorities of the risk for potential outbreaks; this journal is only available by subscription. Limiting the accessibility of such knowledge may have reduced information propagation toward public health actors who were indeed surprised by and unprepared for the 2014 epidemic. Open access (OA) publication can allow for increased access to global health research (GHR)...
August 29, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28771775/outcomes-of-interventions-for-nurse-leaders-wellbeing-at-work-a-quantitative-systematic-review
#11
REVIEW
Arja Häggman-Laitila, Johanna Romppanen
AIM: To gather, assess and synthesise current research knowledge on interventions that aimed to improve nurse leaders' well-being at work. BACKGROUND: The research evidence on interventions for nurse leaders' well-being at work has been sporadic and there are a lack of evidence-based recommendations for effective interventions that inform practice, future studies and education. DESIGN: A quantitative systematic review, in accordance with the Cochrane Collaboration procedures and the reporting guidance in the PRISMA statement...
August 3, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28657802/exiting-the-emergency-medical-services-profession-and-characteristics-associated-with-intent-to-return-to-practice
#12
Rebecca E Cash, Remle P Crowe, Riddhima Agarwal, Severo A Rodriguez, Ashish R Panchal
OBJECTIVE: Inadequate staffing of agencies, increasing attrition rates, and frequent turnover of personnel make employee retention an ongoing concern for Emergency Medical Services (EMS). Faced with increasing demand for EMS, understanding the causes underlying turnover is critical. The objectives of this study were to describe the proportion of individuals that left EMS, likelihood of returning to the profession, and key factors contributing to the decision to leave EMS. METHODS: This was a cross-sectional study of nationally-certified EMS professionals who left EMS...
June 28, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28655365/grade-evidence-to-decision-etd-framework-for-coverage-decisions
#13
Elena Parmelli, Laura Amato, Andrew D Oxman, Pablo Alonso-Coello, Massimo Brunetti, Jenny Moberg, Francesco Nonino, Silvia Pregno, Carlo Saitto, Holger J Schünemann, Marina Davoli
OBJECTIVES: Coverage decisions are decisions by third party payers about whether and how much to pay for technologies or services, and under what conditions. Given their complexity, a systematic and transparent approach is needed. The DECIDE (Developing and Evaluating Communication Strategies to Support Informed Decisions and Practice Based on Evidence) Project, a GRADE (Grading of Recommendations Assessment, Development and Evaluation) Working Group initiative funded by the European Union, has developed GRADE Evidence to Decision (EtD) framework for different types of decisions, including coverage ones...
June 28, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28637571/workforce-issues-in-pediatric-surgery
#14
Don K Nakayama
High salaries indicate a demand for pediatric surgeons in excess of the supply, despite only a slight growth in the pediatric-age population and a sharp increase in numbers of trainees. Top-level neonatal intensive care units require 24-hour-7-day pediatric surgical availability, so hospitals are willing to pay surgeons a premium and engage high-priced locum tenens surgeons to fill vacancies in coverage. With increased supply comes an erosion of the numbers of cases performed by trainees and surgeons in practice...
June 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28623159/epigenetic-biomarkers-and-cardiovascular-disease-circulating-micrornas
#15
David de Gonzalo-Calvo, Eduardo Iglesias-Gutiérrez, Vicenta Llorente-Cortés
MicroRNAs (miRNAs) are a class of small noncoding RNA (20-25 nucleotides) involved in gene regulation. In recent years, miRNAs have emerged as a key epigenetic mechanism in the development and physiology of the cardiovascular system. These molecular species regulate basic functions in virtually all cell types, and are therefore directly associated with the pathophysiology of a large number of cardiovascular diseases. Since their relatively recent discovery in extracellular fluids, miRNAs have been studied as potential biomarkers of disease...
June 13, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28613066/balance-billing-by-health-care-providers-assessing-consumer-protections-across-states
#16
Kevin Lucia, Jack Hoadley, Ashley Williams
ISSUE: Privately insured consumers expect that if they pay premiums and use in-network providers, their insurer will cover the cost of medically necessary care beyond their cost-sharing. However, when obtaining care at emergency departments and in-network hospitals, patients treated by an out-of-network provider may receive an unexpected "balance bill" for an amount beyond what the insurer paid. With no explicit federal protections against balance billing, some states have stepped in to protect consumers from this costly and confusing practice...
June 2017: Issue Brief of the Commonwealth Fund
https://www.readbyqxmd.com/read/28544860/behavioral-processes-in-long-lag-intervention-studies
#17
Dale T Miller, Jennifer E Dannals, Julian J Zlatev
We argue that psychologists who conduct experiments with long lags between the manipulation and the outcome measure should pay more attention to behavioral processes that intervene between the manipulation and the outcome measure. Neglect of such processes, we contend, stems from psychology's long tradition of short-lag lab experiments where there is little scope for intervening behavioral processes. Studying process in the lab invariably involves studying psychological processes, but in long-lag field experiments it is important to study causally relevant behavioral processes as well as psychological ones...
May 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28531819/welfare-consequences-for-people-with-epilepsy-and-their-partners-a-matched-nationwide-study-in-denmark
#18
Poul Jennum, Anne Sabers, Jakob Christensen, Rikke Ibsen, Jakob Kjellberg
PURPOSE: We aimed to evaluate the excess direct and indirect costs associated with epilepsy. METHODS: From the Danish National Patient Registry (1998-2013), we identified people within all ages with an epilepsy diagnosis and matched them to control individuals. Additionally, partners of people with epilepsy were identified, who were compared with control partners. Direct costs included frequencies and costs of hospitalizations and weighted outpatient use according to diagnosis-related group, and specific outpatient costs based on data from the Danish Ministry of Health...
July 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28522118/a-national-survey-of-hdr-source-knowledge-among-practicing-radiation-oncologists-and-residents-establishing-a-willingness-to-pay-threshold-for-cobalt-60-usage
#19
Raymond Mailhot Vega, Wesley Talcott, Omar Ishaq, Patrice Cohen, Christina J Small, Tamara Duckworth, Gustavo Sarria Bardales, Carmen A Perez, Peter B Schiff, William Small, Matthew M Harkenrider
PURPOSE: Ir-192 is the predominant source for high-dose-rate (HDR) brachytherapy in United States markets. Co-60, with longer half-life and fewer source exchanges, has piloted abroad with comparable clinical dosimetry but increased shielding requirements. We sought to identify practitioner knowledge of Co-60 and establish acceptable willingness-to-pay (WTP) thresholds for additional shielding requirements for use in future cost-benefit analysis. METHODS AND MATERIALS: A nationwide survey of U...
July 2017: Brachytherapy
https://www.readbyqxmd.com/read/28499436/inequality-in-healthcare-costs-between-residing-and-non-residing-patients-evidence-from-vietnam
#20
Hieu M Nguyen
BACKGROUND: Place of residence has been shown to impact health. To date, however, previous studies have only focused on the variability in health outcomes and healthcare costs between urban and rural patients. This study takes a different approach and investigates cost inequality facing non-residing patients - patients who do not reside in the regions in which the hospitals are located. Understanding the sources for this inequality is important, as they are directly related to healthcare accessibility in developing countries...
May 12, 2017: International Journal for Equity in Health
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