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Klaus Fritz, Carmen Salavastru, Magdalina Gyurova
INTRODUCTION: This study investigates noninvasive cellulite treatments based on simultaneous application of monopolar radiofrequency (RF) and targeted pressure energy to evaluate efficacy and safety and to see whether simultaneous application has any benefits in noninvasive cellulite treatments. METHODS: Thirty women with cellulite (fibrous/adipose/aqueous types) received 4 gluteofemoral treatments (~24 minutes; ~1000 cm2 ) using a simultaneous application of RF and targeted pressure energy...
March 9, 2018: Journal of Cosmetic Dermatology
Carlos Oscar Uebel, Pedro Salomao Piccinini, Alessandra Martinelli, Daniela Feijó Aguiar, Renato Franz Matta Ramos
Background: Cellulite is one of the most common skin and subcutaneous tissue conditions, affecting predominantly the thighs and hips in post-adolescent women. Its etiology is not well defined, and multiple available treatments show variable efficacy. Objective: To describe a technique for treatment of cellulite of the gluteal region, thighs, and hips through superficial liposuction utilizing a special cannula, combined with subcutaneous autologous fat grafting. Methods: A retrospective review was performed of patients treated over 26 years at the Hospital São Lucas, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil...
February 8, 2018: Aesthetic Surgery Journal
Erol Eli Simsolo, İpek Eroğlu, Sakine Tuncay Tanrıverdi, Özgen Özer
Cellulite is a dermal disorder including the extracellular matrix, the lymphatic and microcirculatory systems and the adipose tissue. Caffeine is used as the active moiety depending its preventive effect on localization of fat in the cellular structure. Hyaluronic acid (hyaluronan-HA) is a natural constituent of skin that generates formation and poliferation of new cells having a remarkable moisturizing ability. The aim of this study is to formulate HA microparticles loaded with caffeine via spray-drying method...
January 29, 2018: AAPS PharmSciTech
Fatma Eldsouky, Howyda Mohamed Ebrahim
BACKGROUND: Cellulite is an irregular alteration of the skin surface giving it cottage cheese appearance. Carboxytherapy is transcutaneous infusion of carbon dioxide into the affected site. Mesolipolysis aims to remove cellulite and improve skin texture. AIMS: To verify the efficacy and safety of carboxytherapy versus mesolipolysis using phosphatidylcholine (PPC) in treatment of cellulite in thighs area. METHODS: Forty-eight female patients with different grades of cellulite at thighs area were enrolled in this study...
January 17, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Adria Y Sadala, Aline F P Machado, Richard E Liebano
BACKGROUND: Carboxytherapy may generate local pain that is considered the main limiting factor in clinical practice. Transcutaneous electric nerve stimulation (TENS) is widely used in the control of acute pain; however, the effect of TENS on pain relief during carboxytherapy has not been studied to date. AIMS: To assess the effect of TENS on pain intensity during carboxytherapy in patients with cellulite in the gluteal region. PATIENTS/METHODS: This randomized clinical trial was conducted with 84 patients, 18-44 years of age, who had moderate cellulite in the gluteal region, according to Cellulite Severity Scale, but never received carboxytherapy...
January 16, 2018: Journal of Cosmetic Dermatology
Laura Cornara, Giulia Pastorino, Barbara Borghesi, Annalisa Salis, Marco Clericuzio, Carla Marchetti, Gianluca Damonte, Bruno Burlando
Seagrasses are high plants sharing adaptive metabolic features with both terrestrial plants and marine algae, resulting in a phytocomplex possibly endowed with interesting biological properties. The aim of this study is to evaluate the in vitro activities on skin cells of an ethanolic extract obtained from the leaves of Posidonia oceanica (L.) Delile, family Potamogetonaceae, herein named Posidonia ethanolic extract (PEE). PEE showed high radical scavenging activity, high phenolic content, and resulted rich in chicoric acid, as determined through HPLC-MS analysis...
January 10, 2018: Marine Drugs
Daniel J Callaghan, Deanne Mraz Robinson, Michael S Kaminer
Cellulite is a condition that affects the majority of postpubertal women and can negatively impact quality of life. This review discusses several proposed pathophysiologies of cellulite, and examines treatment options that have been utilized, focusing on the etiologic factor targeted by the therapies. This approach aims to help clarify the pathogenesis of cellulite and provide a road map for developing effective treatment paradigms for patients.
December 2017: Seminars in Cutaneous Medicine and Surgery
Mario Puviani, Federica Tovecci, Massimo Milani
INTRODUCTION: Gynoid lipodystrophy, also known as cellulite, is a very common skin alteration representing mainly a cosmetic problem rather than a real disease. An effective treatment of cellulite has not been well established. The initial phase of cellulite is characterized by subdermal tissue edema with interstitial fluids retention. A new hypertonic topical product with draining action (HTC) containing NaCl 13%, escine, caffeine, and beta-sitosterol has been recently developed. A 28-day double-blind placebo-controlled study has shown that this cream is able to reduce thigh circumference and the thickness of adipose tissue...
December 4, 2017: Journal of Cosmetic Dermatology
Tae Woo Jung, Sung Tae Kim, Jun Ho Lee, Soo In Chae, Kwang Woo Hwang, Yoon Hee Chung, Hyoung-Chun Kim, A M Abd El-Aty, Tae Jin Lee, Eon Sub Park, Ji Hoon Jeong
A phosphatidylcholine (PPC) formulation has been used to treat cellulite; however, its underlying mechanism of action remains unclear. In this study, we demonstrated that PPC induces lipolysis and apoptosis in adipocytes, and evaluated a possible tumor necrosis factor alpha (TNFα)-dependent pathway, whereby PPC exerts these effects. For in vitro study, fully differentiated 3T3-L1 cells, mouse adipocytes were treated with various concentrations of PPC and cell apoptosis and lipolysis were assayed. For in vivo experiments, mice fed on a high-fat diet for 8 weeks were injected twice to abdominal subcutaneous fat tissues of either vehicle or PPC...
2018: Pharmacology
José Maria Pereira de Godoy, Ana Carolina Pereira de Godoy, Maria de Fatima Guerreiro Godoy
No abstract text is available yet for this article.
October 11, 2017: Dermatology Reports
Mahmoud H Teaima, Sally A Abdelhalim, Mohamed A El-Nabarawi, Dalia A Attia, Doaa A Helal
Cellulite is a common topographical alteration where skin acquires an orange peel or mattress appearance with alterations in adipose tissue and microcirculation. This work aims to develop and evaluate a topical niosomal gel formulae with good permeation to reach the subcutaneous fat layer. Several caffeine niosomal dispersions were prepared and incorporated into gel formulae using Carbopol 940 polymer, chemical penetration enhancers, and iontophoresis, then the prepared gels were applied onto the skin of rats and anticellulite activity of caffeine from the prepared gels compared to that of the commercial product Cellu Destock(®) was evaluated by histological study of the skin and measurement of plasma level of caffeine passing through the skin using liquid chromatography (LC/MS-MS)...
October 17, 2017: Drug Development and Industrial Pharmacy
N Li, L G Yu, M Chen, L Yang, Z R Qin, Y Jiang
Objective: To investigate the clinical characteristics of orbital complications due to rhinosinusitis and to provide the basis for the diagnosis and treatment of this disease. Methods: Retrospectively analyzed the clinical data of 28 patients with orbital complications due to rhinosinusitis who were admitted into the Affiliated Hospital of Qingdao University, Department of Otorhinolaryngology from August 2009 to April 2017. In all 28 cases, there were 1 case with preseptal cellulites, 9 cases with orbital cellulites, 13 cases with subperiosteal orbital abscess and 5 cases with orbital abscess...
September 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Jason R Brown, D Micah Milgraum, Farhaad R Riyaz, Marla N Jahnke, Prasad John Thottam
INTRODUCTION: Epidermolysis bullosa (EB) is a spectrum of mechanobullous disorders characterized by blistering following minor trauma or traction to the skin. Hearing loss in this population is poorly described in the otolaryngology literature, and its treatment oftentimes results in external auditory canal skin irritation. CASE PRESENTATION: We present the case of a 26-year-old female with EB and mixed hearing loss unable to wear conventional hearing aids due to sequelae of the external auditory canals...
November 2017: Annals of Otology, Rhinology, and Laryngology
Gabriela Casabona, Gregório Pereira
Age-associated skin laxity contributes to worsening of cellulite appearance. This study evaluated the effects of microfocused ultrasound with visualization (MFU-V; Ultherapy) in combination with diluted calcium hydroxylapatite (CaHA; Radiesse) on cellulite appearance and on neocollagenesis. METHODS: Twenty women (18-55 years old) with skin laxity and moderate-to-severe cellulite on the buttocks and thighs were retrospectively enrolled. MFU-V was applied using 4 and 7 MHz transducers (25 lines/transducer/site) and immediately followed by subdermal CaHA injection (1 ml/buttock or thigh)...
July 2017: Plastic and Reconstructive Surgery. Global Open
Manuel Albornoz-Cabello, Alfonso Javier Ibáñez-Vera, Blanca De la Cruz-Torres
INTRODUCTION: Despite high incidence rate of cellulite, there are few studies regarding its treatment. Most of them present non-validated evaluation tools. Radio frequency is a focused treatment very used in aesthetics to reduce it. OBJECTIVES: To know the efficacy of Monopolar Dielectric Radio frequency (MDR) treatment in dynamic applications to reduce cellulite, panniculus adiposus and gluteal and posterior thigh regions. METHODS: Experimental study consisting of inferior members of nine women...
November 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Michael S Kaminer, William P Coleman, Robert A Weiss, Deanne M Robinson, Jody Grossman
BACKGROUND: Cellulite is a common female cosmetic concern for which no single treatment option had been proven effective over the long term. A novel tissue stabilized-guided subsicion system (TS-GS system) has demonstrated significant reduction in the appearance of cellulite after treatment. OBJECTIVE: The objective of this extended follow-up period was to assess the effectiveness of TS-GS out to 3 years after initial treatment. PATIENTS AND METHODS: After completing an open-label, multicenter, pivotal study, 45 subjects were followed for an extended period of up to 3 years after receiving a single treatment using the TS-GS system...
October 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Kao-Chi Cheng, Po-Tsung Huang, Chiu-Shong Liu, Wen-Yuan Lin
In the hospice ward where patients are in the terminal stages of cancer, it is common practice to give them a subcutaneous injection of pain relievers to reduce their pain and make them more comfortable. Most of these patients are elderly and have low blood pressure or poor veins, which often makes it difficult to inject them because of the calcification at previous injection sites. Thus, subcutaneous injections are a convenient way to maintain analgesia and patient comfort. Our patient, a 73-year-old aboriginal woman, was diagnosed with gastric adenocarcinoma and peritoneal carcinomatosis in March, 2004...
June 2017: BioMedicine
Débora A Oliveira Modena, Caroline Nogueira da Silva, Clovis Grecco, Renata Michelini Guidi, Renata Gomes Moreira, Andresa A Coelho, Estela Sant'Ana, José Ricardo de Souza
Extracorporeal Shockwave Therapy (ESWT) has had a wide use in rehabilitation, and has presented positive effects in the treatment of unaesthetic affections. The objective of the present study was to search, in the literature, the mechanisms of action and the physiological aspects of shockwaves acting on the biological tissue to improve the condition of cellulite and localized fat. The systematic review of the literature was carried out in the period of September 2016 to February 2017 based on the bibliographic databases such as Lilacs, Medline, PubMed, and SciELO...
October 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Malinowska Sylwia, Mlosek Robert Krzysztof
BACKGROUND: Cellulite affects the majority of women and is an unacceptable cosmetic defect. Therefore, effective methods for cellulite reduction are being sought. Intradermal mesotherapy is one of such methods. OBJECTIVE: The aim of the study was to assess the efficacy of intradermal mesotherapy in cellulite reduction, using conventional and high-frequency ultrasound. METHODS: Twenty-one women with cellulite underwent a series of intradermal mesotherapy procedures...
October 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Mónica Elisabeth Martínez, Sandra Liliana Grenón, Oscar Herminio López, Lorena Beatriz Leguizamón, Marta Eugenia Mollerach, Martha Helena von Specht
The role of Streptococcus pneumoniae as a causative agent of skin and soft tissue infections (SSTI) is unusual and its clinical interpretation is difficult. We describe here three cases of SSTI due to S. pneumoniae in patients admitted to the Provincial Pediatric Hospital of Misiones, Argentina that were detected during 10 years of invasive disease (ID) surveillance documented in 2010, 2011 and 2015. These cases involved two girls aged 8 and 7 months old, and a two-year-old male child with diagnoses of gluteal abscess, preseptal cellulites and pyoderma respectively...
April 14, 2017: Revista Argentina de Microbiología
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