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https://www.readbyqxmd.com/read/28414439/mitigation-of-thin-film-composite-membrane-biofouling-via-immobilizing-nano-sized-biocidal-reservoirs-in-the-membrane-active-layer
#1
Alireza Zirehpour, Ahmad Rahimpour, Ahmad Arabi Shamsabadi, Mohammad Sharifian Gh, Masoud Soroush
This work investigates the use of a silver-based metal-organic framework (MOF) for mitigating biofouling in forward-osmosis thin-film composite (TFC) membranes. This is the first study of the use of MOFs for biofouling control in membranes. MOF nanocrystals were immobilized in the active layer of the membranes via dispersing them in the organic solution used for interfacial polymerization. Field emission scanning electron microscopy (FE-SEM) and X-ray photoelectron spectroscope (XPS) characterization results showed the presence of the MOF nanocrystals in the active layer of the membranes...
April 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28412549/enhancing-boron-rejection-in-fo-using-alkaline-draw-solutions
#2
Yi-Ning Wang, Weiyi Li, Rong Wang, Chuyang Y Tang
This study provides a novel method to enhance boron removal in a forward osmosis (FO) process. It utilizes the reverse solute diffusion (RSD) of ions from alkaline draw solutions (DSs) and the concentration polarization of the hydroxyl ions to create a highly alkaline environment near the membrane active surface. The results show that boron rejection can be significantly enhanced by increasing the pH of NaCl DS to 12.5 in the active-layer-facing-feed-solution (AL-FS) orientation. The effect of RSD enhanced boron rejection was further promoted in the presence of concentration polarization (e...
April 10, 2017: Water Research
https://www.readbyqxmd.com/read/28409819/spermicidal-efficacy-of-vrp-a-synthetic-cationic-antimicrobial-peptide-inducing-apoptosis-and-membrane-disruption
#3
Prasanta Ghosh, Arpita Bhoumik, Sudipta Saha, Sandipan Mukherjee, Sarfuddin Azmi, Jimut Kanti Ghosh, Sandhya Rekha Dungdung
Presently available contraceptives are mostly hormonal or detergent in nature with numerous side effects like irritation, lesion, inflammation in vagina, alteration of body homeostasis etc. Antimicrobial peptides with spermicidal activity but without adverse effects may be suitable alternatives. In the present study spermicidal activity of a cationic antimicrobial peptide VRP on human spermatozoa has been elucidated. Progressive forward motility of human spermatozoa was instantly stopped after 100 µM VRP treatment and at 350 µM all kinds of sperm motility ceased within 20 seconds as assessed by the Sander-Cramer assay...
April 14, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28400324/impact-of-anatase-titanium-dioxide-nanoparticles-on-mutagenic-and-genotoxic-response-in-chinese-hamster-lung-fibroblast-cells-v-79-the-role-of-cellular-uptake
#4
Abhishek Kumar Jain, Violet Aileen Senapati, Divya Singh, Kavita Dubey, Renuka Maurya, Alok Kumar Pandey
The unique physico-chemical properties of nano crystalline anatase titanium dioxide nanoparticles (TiO2 NPs) render them with different biological and chemical activities. Hence, it is widely used in industrial and consumer applications. Previous studies have shown the genotoxicity of TiO2 NPs. However, there is a paucity of data regarding mutagenicity of these NPs. In the present study, the cellular uptake, sub-cellular localization, cytotoxicity and short term DNA interaction of TiO2 NPs (1-100 μgmL(-1)) of diameter ranging from 12 to 25 nm on mammalian lung fibroblast cells (V-79) has been studied...
April 8, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28388693/a-role-for-glycolipid-biosynthesis-in-severe-fever-with-thrombocytopenia-syndrome-virus-entry
#5
Mary Jane Drake, Benjamin Brennan, Kenneth Briley, Stephen M Bart, Eric Sherman, Agnieszka M Szemiel, Madeleine Minutillo, Frederic D Bushman, Paul Bates
A novel bunyavirus was recently found to cause severe febrile illness with high mortality in agricultural regions of China, Japan, and South Korea. This virus, named severe fever with thrombocytopenia syndrome virus (SFTSV), represents a new group within the Phlebovirus genus of the Bunyaviridae. Little is known about the viral entry requirements beyond showing dependence on dynamin and endosomal acidification. A haploid forward genetic screen was performed to identify host cell requirements for SFTSV entry...
April 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28388525/development-of-combined-nanofiltration-and-forward-osmosis-process-for-production-of-ethanol-from-pretreated-rice-straw
#6
Masafumi Shibuya, Kengo Sasaki, Yasuhiro Tanaka, Masahiro Yasukawa, Tomoki Takahashi, Akihiko Kondo, Hideto Matsuyama
A membrane process combining nanofiltraion (NF) and forward osmosis (FO) was developed for the sugar concentration with the aim of high bio-ethanol production from the liquid fraction of rice straw. The commercial NF membrane, ESNA3, was more adequate for removal of fermentation inhibitors (such as acetic acid) than the FO membrane, whereas the commercial FO membrane, TFC-ES, was more adequate for concentration of the sugars than the NF membrane. The liquid fraction was subjected to the following process: NF concentration with water addition (NF(+H2O))→enzymatic hydrolysis→FO concentration...
March 28, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28387760/endothelial-keratoplasty-is-descemet-membrane-endothelial-keratoplasty-the-way-forward-yes
#7
V S Liarakos, M Tsatsos, M Satue, G R J Melles
No abstract text is available yet for this article.
April 7, 2017: Eye
https://www.readbyqxmd.com/read/28380231/forward-osmosis-in-wastewater-treatment-processes
#8
Jasmina Korenak, Subhankar Basu, Malini Balakrishnan, Claus Hélix-Nielsen, Irena Petrinic
In recent years, membrane technology has been widely used in wastewater treatment and water purification. Membrane technology is simple to operate and produces very high quality water for human consumption and industrial purposes. One of the promising technologies for water and wastewater treatment is the application of forward osmosis. Essentially, forward osmosis is a process in which water is driven through a semipermeable membrane from a feed solution to a draw solution due to the osmotic pressure gradient across the membrane...
2017: Acta Chimica Slovenica
https://www.readbyqxmd.com/read/28379343/jnk-and-p38-mapk-pathways-link-capacitation-with-apoptosis-and-seminal-plasma-proteins-protect-sperm-by-interfering-with-both-routes
#9
Carolina Luna, Noelia Mendoza, Adriana Casao, Rosaura Pérez-Pé, José A Cebrián-Pérez, Teresa Muiño-Blanco
The Mitogen-activated protein kinase (MAPK) JNK and p38 signaling cascades are involved in triggering apoptosis in somatic cells. Given that spermatozoa are able to undergo apoptosis, we tested the hypothesis that these pathways might be functional in ram spermatozoa as two signal transduction mechanisms that contribute to the modulation of capacitation and apoptosis. Indirect immunofluorescence and western-blot analysis evidenced the presence of JNK and p38 in ram spermatozoa. To verify the involvement of these enzymes in sperm physiology, we determined the effect of specific inhibitors of JNK or p38 on in vitro capacitation induced with either cAMP-elevating agents or Epidermal Growth Factor (EGF)...
March 31, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28359067/triggering-of-suicidal-erythrocyte-death-by-gefitinib
#10
Abdulla Al Mamun Bhuyan, Teresa Wagner, Hang Cao, Florian Lang
BACKGROUND/AIMS: The epidermal growth factor receptor-tyrosine kinase inhibitor gefitinib is effective against several malignancies and is mainly utilized in the treatment of epidermal growth factor receptor mutation positive non-small cell lung cancer. The anti-cancer effect of the drug involves stimulation of apoptosis. Side effects of gefitinib include anemia. At least in theory, the development of anemia during gefitinib treatment could result from triggering of eryptosis, the suicidal erythrocyte death characterized by cell shrinkage and by cell membrane scrambling with phosphatidylserine translocation to the erythrocyte surface...
March 29, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28357396/chlamydia-trachomatis-struggle-to-keep-its-host-alive
#11
COMMENT
Barbara S Sixt, Raphael H Valdivia, Guido Kroemer
Bacteria of the phylum Chlamydiae infect a diverse range of eukaryotic host species, including vertebrate animals, invertebrates, and even protozoa. Characteristics shared by all Chlamydiae include their obligate intracellular lifestyle and a biphasic developmental cycle. The infectious form, the elementary body (EB), invades a host cell and differentiates into the replicative form, the reticulate body (RB), which proliferates within a membrane-bound compartment, the inclusion. After several rounds of division, RBs retro-differentiate into EBs that are then released to infect neighboring cells...
March 2, 2017: Microbial Cell
https://www.readbyqxmd.com/read/28355275/investigating-time-efficiency-of-forward-masking-paradigms-for-estimating-basilar-membrane-input-output-characteristics
#12
Michal Fereczkowski, Morten L Jepsen, Torsten Dau, Ewen N MacDonald
It is well known that pure-tone audiometry does not sufficiently describe individual hearing loss (HL) and that additional measures beyond pure-tone sensitivity might improve the diagnostics of hearing deficits. Specifically, forward masking experiments to estimate basilar-membrane (BM) input-output (I/O) function have been proposed. However, such measures are very time consuming. The present study investigated possible modifications of the temporal masking curve (TMC) paradigm to improve time and measurement efficiency...
2017: PloS One
https://www.readbyqxmd.com/read/28355079/ultrafast-charge-transfer-between-light-absorber-and-co3o4-water-oxidation-catalyst-across-molecular-wires-embedded-in-silica-membrane
#13
Eran Edri, Jason K Cooper, Ian D Sharp, Dirk M Guldi, Heinz Frei
The mechanism of visible light-induced hole transfer from a molecular light absorber, in the form of a free-base porphyrin, coupled to a Co3O4 nanoparticle catalyst for water oxidation by a molecular wire (p-oligo(phenylenevinylene) featuring three aryl units) is investigated by transient absorption spectroscopy. The wires are covalently anchored on the Co3O4 surface and embedded in a dense, yet ultrathin (2 nm), silica layer that separates light absorber and catalyst. The porphyrin is electrostatically adsorbed on the silica surface, and aqueous colloidal solutions of the core-shell particles are used for transient optical measurements...
April 6, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28342835/lipids-in-exosomes-current-knowledge-and-the-way-forward
#14
REVIEW
Tore Skotland, Kirsten Sandvig, Alicia Llorente
Lipids are essential components of exosomal membranes, and it is well-known that specific lipids are enriched in exosomes compared to their parent cells. In this review we discuss current knowledge about the lipid composition of exosomes. We compare published data for different lipid classes in exosomes, and what is known about their lipid species, i.e. lipid molecules with different fatty acyl groups. Moreover, we elaborate on the hypothesis about hand-shaking between the very-long-chain sphingolipids in the outer leaflet and PS 18:0/18:1 in the inner leaflet, and we propose this to be an important mechanism in membrane biology, not only for exosomes...
March 23, 2017: Progress in Lipid Research
https://www.readbyqxmd.com/read/28342589/energy-consumption-by-forward-osmosis-treatment-of-landfill-leachate-for-water-recovery
#15
Syeed Md Iskander, Shiqiang Zou, Brian Brazil, John T Novak, Zhen He
Forward osmosis (FO) is an alternative approach for treating landfill leachate with potential advantages of reducing leachate volume and recovering high quality water for direct discharge or reuse. However, energy consumption by FO treatment of leachate has not been examined before. Herein, the operational factors such as recirculation rates and draw concentrations were studied for their effects on the quantified energy consumption by an FO system treating actual leachate collected from two different landfills...
March 22, 2017: Waste Management
https://www.readbyqxmd.com/read/28342575/performance-of-a-novel-baffled-osmotic-membrane-bioreactor-microfiltration-hybrid-system-under-continuous-operation-for-simultaneous-nutrient-removal-and-mitigation-of-brine-discharge
#16
Nirenkumar Pathak, Laura Chekli, Jin Wang, Youngjin Kim, Sherub Phuntsho, Sheng Li, Noreddine Ghaffour, TorOve Leiknes, Hokyong Shon
The present study investigated the performance of an integrated osmotic and microfiltration membrane bioreactor system for wastewater treatment employing baffles in the reactor. Thus, this reactor design enables both aerobic and anoxic processes in an attempt to reduce the process footprint and energy costs associated with continuous aeration. The process performance was evaluated in terms of water flux, salinity build up in the bioreactor, organic and nutrient removal and microbial activity using synthetic reverse osmosis (RO) brine as draw solution (DS)...
March 14, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28342057/preparation-of-drug-loaded-plga-peg-nanoparticles-by-membrane-assisted-nanoprecipitation
#17
Airama Albisa, Emma Piacentini, Victor Sebastian, Manuel Arruebo, Jesus Santamaria, Lidietta Giorno
PURPOSE: The aim of this work is to develop a scalable continuous system suitable for the formulation of polymeric nanoparticles using membrane-assisted nanoprecipitation. One of the hurdles to overcome in the use of nanostructured materials as drug delivery vectors is their availability at industrial scale. Innovation in process technology is required to translate laboratory production into mass production while preserving their desired nanoscale characteristics. METHODS: Membrane-assisted nanoprecipitation has been used for the production of Poly[(D,L lactide-co-glycolide)-co-poly ethylene glycol] diblock) (PLGA-PEG) nanoparticles using a pulsed back-and-forward flow arrangement...
March 24, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28338480/the-challenges-in-predicting-ecmo-survival-and-a-path-forward
#18
Marco Huesch, Christopher Brehm
Extracorporeal membrane oxygenation (ECMO) support is a life-saving but complex technique for patients suffering from severe cardiac and/or pulmonary dysfunction. Increasingly greater utilization in the last 15 years means that a suite of mortality risk analytics is both feasible for researchers and required by clinicians, patients, administrators and insurers. We argue that to date, research into such risk analytics has been insufficient and does not adequately reflect the various indications and configurations of ECLS...
March 22, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28334923/validated-rp-hplc-dad-method-for-the-quantification-of-insect-repellent-ethyl-2-aminobenzoate-in-membrane-moderated-matrix-type-monolithic-polymeric-device
#19
Johirul Islam, Kamaruz Zaman, Srijita Chakrabarti, Nilutpal Sharma Bora, Santa Mandal, Manash Pratim Pathak, Pakalapati Srinivas Raju, Pronobesh Chattopadhyay
A simple, accurate and sensitive reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed for the estimation of ethyl 2-aminobenzoate (EAB) in a matrix type monolithic polymeric device and validated as per the International Conference on Harmonization guidelines. The analysis was performed isocratically on a ZORBAX Eclipse plus C18 analytical column (250 × 4.4 mm, 5 μm) and a diode array detector (DAD) using acetonitrile and water (75:25 v/v) as the mobile phase by keeping the flow-rate constant at 1...
March 14, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/28332607/-breakthrough-osmosis-and-unusually-high-power-densities-in-pressure-retarded-osmosis-in-non-ideally-semi-permeable-supported-membranes
#20
Andriy Yaroshchuk
Osmosis is the movement of solvent across a membrane induced by a solute-concentration gradient. It is very important for cell biology. Recently, it has started finding technological applications in the emerging processes of Forward Osmosis and Pressure-Retarded Osmosis. They use ultrathin and dense membranes supported mechanically by much thicker porous layers. Until now, these processes have been modelled by assuming the membrane to be ideally-semipermeable. We show theoretically that allowing for even minor deviations from ideal semipermeability to solvent can give rise to a previously overlooked mode of "breakthrough" osmosis...
March 23, 2017: Scientific Reports
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