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https://www.readbyqxmd.com/read/28637305/left-atrial-structure-and-function-in-cardiac-amyloidosis
#1
Kotaro Nochioka, Candida Cristina Quarta, Brian Claggett, Gabriela Querejeta Roca, Claudio Rapezzi, Rodney H Falk, Scott D Solomon
Aims: Although cardiac amyloidosis (CA) is characterized by significant left atrial (LA) dilatation, the characteristics of LA function remain to be fully investigated. Methods and results: We assessed LA function by speckle-tracking echocardiography in 124 patients with CA and sinus rhythm: 68 with light chain (AL), 29 with mutant (ATTRm), 27 with wild-type (ATTRwt) transthyretin amyloidosis. Conventional and strain-derived parameters, including LA peak longitudinal strain (LS) and strain rate (peak LSR: reservoir function; early LSR: conduit function; late LSR: active function), were assessed compared between CA patients and 20 healthy controls of similar age and gender...
June 16, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28637227/echocardiographic-reference-ranges-for-normal-left-ventricular-2d-strain-results-from-the-eacvi-norre-study
#2
Tadafumi Sugimoto, Raluca Dulgheru, Anne Bernard, Federica Ilardi, Laura Contu, Karima Addetia, Luis Caballero, Natela Akhaladze, George D Athanassopoulos, Daniele Barone, Monica Baroni, Nuno Cardim, Andreas Hagendorff, Krasimira Hristova, Teresa Lopez, Gonzalo de la Morena, Bogdan A Popescu, Marie Moonen, Martin Penicka, Tolga Ozyigit, Jose David Rodrigo Carbonero, Nico van de Veire, Ralph Stephan von Bardeleben, Dragos Vinereanu, Jose Luis Zamorano, Yun Yun Go, Monica Rosca, Andrea Calin, Julien Magne, Bernard Cosyns, Stella Marchetta, Erwan Donal, Gilbert Habib, Maurizio Galderisi, Luigi P Badano, Roberto M Lang, Patrizio Lancellotti
Aims: To obtain the normal ranges for 2D echocardiographic (2DE) measurements of left ventricular (LV) strain from a large group of healthy volunteers accounting for age and gender. Methods and results: A total of 549 (mean age: 45.6 ± 13.3 years) healthy subjects were enrolled at 22 collaborating institutions of the Normal Reference Ranges for Echocardiography (NORRE) study. 2DE data sets have been analysed with a vendor-independent software package allowing homogeneous measurements irrespective of the echocardiographic equipment used to acquire the data sets...
June 16, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28636515/a-brief-period-of-intensive-cardiac-rehabilitation-improves-global-longitudinal-strain-and-diastolic-function-after-a-first-uncomplicated-myocardial-infarction
#3
Gabriella Malfatto, Miriam Revera, Giovanna Branzi, Francesca Ciambellotti, Alessia Giglio, Simonetta Blengino, Matteo Oldani, Camilla Facchini, Gianfranco Parati, Mario Facchini
Objectives In patients with abnormal left ventricular ejection fraction (LVEF) after acute myocardial infarction (AMI), cardiac rehabilitation with physical training prevents cardiac remodelling. To define the role of rehabilitation in the recovery of ventricular function in less severe cases, we studied its effects on more refined indexes of left ventricular function in uncomplicated, low-risk patients. Methods and results Fifty-five patients underwent percutaneous coronary revascularization after uncomplicated first AMI...
March 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28634695/assessment-of-early-diastolic-intraventricular-pressure-gradient-in-the-left-ventricle-among-patients-with-repaired-tetralogy-of-fallot
#4
Maki Kobayashi, Ken Takahashi, Mariko Yamada, Kana Yazaki, Kotoko Matsui, Noboru Tanaka, Sachie Shigemitsu, Katsumi Akimoto, Masahiko Kishiro, Keisuke Nakanishi, Shiori Kawasaki, Masaki Nii, Keiichi Itatani, Toshiaki Shimizu
Assessment of left ventricular (LV) dysfunction is vital in patients with repaired tetralogy of Fallot (rTOF). The early diastolic intraventricular pressure gradient (IVPG) in the LV plays an important role in diastolic function. IVPG is calculated as the intraventricular pressure difference divided by the LV length, which allows to account for differences in LV size and therefore calculate IVPG in children. We aimed to investigate the mechanisms of LV diastolic dysfunction by measuring mid-to-apical IVPG as an indicator of the active suction force sucking blood from the left atrium into the LV...
June 20, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28631361/optimal-right-heart-filling-pressure-in-acute-respiratory-distress-syndrome-determined-by-strain-echocardiography
#5
Romel Garcia-Montilla, Faryal Imam, Mi Miao, Kathryn Stinson, Akram Khan, Stephen Heitner
INTRODUCTION: Right ventricular (RV) systolic dysfunction is common in acute respiratory distress syndrome (ARDS). While preload optimization is crucial in its management, dynamic fluid responsiveness indices lack reliability, and there is no consensus on target central venous pressure (CVP). We analyzed the utility of RV free wall longitudinal strain (RVFWS) in the estimation of optimal RV filling pressure in ARDS. METHODS: A retrospective cross-sectional analysis of clinical data and echocardiograms of patients with ARDS was performed...
June 2017: Echocardiography
https://www.readbyqxmd.com/read/28627046/donor-specific-antibodies-are-associated-with-micro-and-macrovascular-coronary-disease-restrictive-myocardial-damage-and-poor-outcome-in-heart-transplanted-patients
#6
Tor Skibsted Clemmensen, Pernille Koefoed-Nielsen, Lis-Ann Jensen, Steen Hvitfeldt Poulsen, Niels Ramsing Holm, Brian Bridal Løgstrup, Evald Høj Christiansen, Jouke Dijkstra, Kamilla Pernille Bjerre Valen, Hans Eiskjaer
AIMS: We examined the relationship between donor-specific HLA antibody (DSA) presence and graft function, hemodynamics, cardiac allograft vasculopathy (CAV), and major adverse cardiac events (MACE) in stable long-term heart-transplanted (HTx) patients. METHODS: Sera from 79 patients (median 7.5 years after HTx) were analyzed for DSA presence. Graft function was evaluated by echocardiography and right heart catheterization. CAV-burden was determined by coronary angiography, optical coherence tomography (OCT), and coronary flow velocity reserve (CFVR)...
June 19, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28616564/regression-of-cardiac-amyloidosis-following-stem-cell-transplantation-a-comparison-between-echocardiography-and-cardiac-magnetic-resonance-imaging-in-long-term-survivors
#7
Benjamin Thomas Fitzgerald, John Bashford, Katrina Newbigin, Gregory Malcolm Scalia
BACKGROUND: AL amyloidosis and multiple myeloma result in extracellular deposition of insoluble fibrillary protein in tissue and organs. Untreated median survival is very poor, and even worse with cardiac involvement. Chemotherapy and peripheral blood stem cell transplantation (PBSCT) have been shown to dramatically improve survival, with hematologic remission documented. Regression of cardiac changes has previously been shown, as assessed by echocardiography (TTE) and cardiac magnetic resonance imaging (CMR)...
March 2017: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28616561/left-atrial-appendage-function-assessment-and-thrombus-identification
#8
Jacek Kurzawski, Agnieszka Janion-Sadowska, Marcin Sadowski
BACKGROUND: The diagnosis of thrombus in the left atrium in patients with persistent atrial fibrillation (AF) and may be inconsistent because of variability in thrombus morphology. In some cases it is challenging and requires unusual approach. New Doppler-derived methods might be helpful to identify such thrombi. We evaluated quantitative differences in mechanical function of the left atrial appendage (LAA) basal segments using tissue Doppler imaging (TDI)and speckle tracking echocardiography (STE) in patients with non-valvular AF with and without LAA thrombus and compared them with SR patients...
March 2017: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28616541/accuracy-of-quantitative-echocardiographic-measures-of-right-ventricular-function-as-compared-to-cardiovascular-magnetic-resonance
#9
Christian R Hamilton-Craig, Kathy Stedman, Ryan Maxwell, Bonita Anderson, Tony Stanton, Jonathan Chan, Akira Yamada, Gregory M Scalia, Darryl J Burstow
BACKGROUND: Many echocardiographic parameters have been proposed to evaluate right ventricular (RV) systolic function. We comprehensively assessed a wide range of quantitative echocardiographic parameters in a single cohort compared with same-day cardiovascular magnetic resonance (CMR). METHODS AND RESULTS: 92 subjects were examined prospectively: Group 1 consisted of 46 healthy controls (21 males, 33.4 ± 11.4 years), Group 2 consisted of 46 patients (20 males, 38...
September 2016: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28612903/the-value-of-left-atrial-strain-and-strain-rate-in-predicting-left-atrial-appendage-stasis-in-patients-with-nonvalvular-atrial-fibrillation
#10
Mengruo Zhu, Man Wang, Xinxin Ma, Dongyan Zheng, Yueli Zhang
BACKGROUND: This study aimed to investigate the value of left atrial (LA) strain and strain rate (S/SR) by transthoracic echocardiography (TTE) in predicting left atrial appendage (LAA) stasis, in order to find a way for LAA stasis screening which is easily performed in patients with nonvalvular atrial fibrillation (NVAF). METHODS: One hundred and thirty NVAF patients prepared for AF ablation were enrolled. TTE and transesophageal echocardiography (TEE) were performed in all patients...
June 14, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28610944/bilateral-leg-oedema-after-bariatric-surgery-a-selenium-deficient-cardiomyopathy
#11
Pierre-Laurent Massoure, Olivier Camus, Laurent Fourcade, Fabrice Simon
This report describes a case of selenium-deficient cardiomyopathy secondary to bariatric surgery (Roux-en-Y gastric bypass surgery). A 40 year-old woman presented with bilateral leg oedema nine months after the surgical procedure. Timely diagnosis of selenium-deficient cardiomyopathy was due to the recognition of symptoms of heart failure, increased NT pro-BNP level, detection of myocardial diastolic dysfunction and impaired left ventricular global longitudinal strain by echocardiography, and early identification of selenium deficiency...
June 10, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28607564/subclinical-left-ventricular-systolic-dysfunction-in-patients-with-metabolic-syndrome-a-case-control-study-using-two-dimensional-speckle-tracking-echocardiography
#12
Alireza Moaref, Majid Faraji, Maryam Tahamtan
BACKGROUND: The dramatic increase in the prevalence of metabolic syndrome is associated with more increased cardiovascular morbidity and mortality in this group. Some recent studies suggested that metabolic syndrome is associated with increased risk of subclinical left ventricular (LV) systolic dysfunction. In the present cross-sectional case-control study, the utility of two-dimensional speckle tracking echocardiography (STE) was examined to detect early LV systolic dysfunction in this population...
November 2016: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/28606187/investigation-on-left-ventricular-multi-directional-deformation-in-patients-of-hypertension-with-different-lvef
#13
Huimei Huang, Qinyun Ruan, Meiyan Lin, Lei Yan, Chunyan Huang, Liyun Fu
BACKGROUND: This study is aimed at investigating myocardial multi-directional systolic deformation in hypertensive with different left ventricular ejection fraction (LVEF), and exploring its contribution to LVEF. METHODS: One hundred and twenty-three patients with primary hypertension (HT) were divided into group A (LVEF ≥ 55%), group B (45% ≤ LVEF < 50%, or 50% ≤ LVEF < 55% + LVEDVI ≥ 97 ml/m(2)), and group C (LVEF < 45%). Two-dimensional strain echocardiography (2DSE) including LV longitudinal strain (SL), radial strain (SR) and circumferential strain (SC) were measured...
June 12, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28604759/markers-of-maternal-and-infant-metabolism-are-associated-with-ventricular-dysfunction-in-infants-of-obese-women-with-type-2-diabetes
#14
W Todd Cade, Philip T Levy, Rachel A Tinius, Mehgna D Patel, Swati Choudhry, Mark R Holland, Gautam K Singh, Alison G Cahill
BACKGROUND: To test the hypothesis that infants born to obese women with pregestational type 2 diabetes mellitus (IBDM) have ventricular dysfunction at one month that is associated with markers of maternal lipid and glucose metabolism. METHODS: In a prospective observational study of IBDM (OB+DM, n=25), echocardiography measures of septal, left (LV) and right ventricular (RV) function and structure were compared at one month of age to infants born to OB mothers without DM (OB, n=24), and non-OB without DM (Lean, n=23)...
June 12, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28602206/strain-rate-in-children-and-young-piglets-mirrors-changes-in-contractility-and-demonstrates-a-force-frequency-relationship
#15
Silvia V Alvarez, Etienne Fortin-Pellerin, Mohammed Alhabdan, Jesus S Lomelin, Michal Kantoch, Joseph Atallah, Lisa K Hornberger, James Y Coe, Po-Yin Cheung, Edythe B Tham, Kandice Mah, Lily Lin, Lindsay Mills, Nee S Khoo
BACKGROUND: In adult humans and pig models, strain rate (SR) correlates strongly with invasive measures of contractility but does not demonstrate a force-frequency relationship, which is a fundamental behavior of myocardial contraction. Given the considerable maturational changes of the myocardium from fetal stages to adulthood, extrapolation of adult findings to the young heart may not be appropriate. We sought to evaluate the SR response of the immature heart to increased heart rate (HR) and inotropic stimulation...
June 8, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28599827/late-detection-of-left-ventricular-dysfunction-using-two-dimensional-and-three-dimensional-speckle-tracking-echocardiography-in-patients-with-history-of-nonsevere-acute-myocarditis
#16
Thibault Caspar, Marie Fichot, Mickaël Ohana, Soraya El Ghannudi, Olivier Morel, Patrick Ohlmann
BACKGROUND: Acute myocarditis (AM) often involves the left ventricular (LV) subepicardium that might be displayed by cardiac magnetic resonance even late after the acute phase. In the absence of global or regional LV dysfunction, conventional transthoracic echocardiography (TTE) does not accurately identify tissue sequelae of AM. We sought to evaluate the diagnostic value of two-dimensional (2D) and three-dimensional (3D) speckle-tracking echocardiography to identify patients with a history of AM with preserved LV ejection fraction (LVEF)...
June 6, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28599826/prognostic-value-of-left-ventricular-deformation-parameters-in-patients-with-severe-aortic-stenosis-a-pilot-study-of-the-usefulness-of-strain-echocardiography
#17
Lars Gunnar Klaeboe, Trine F Haland, Ida S Leren, Rachel M A Ter Bekke, Pål H Brekke, Helge Røsjø, Torbjørn Omland, Lars Gullestad, Svend Aakhus, Kristina H Haugaa, Thor Edvardsen
BACKGROUND: In patients with aortic stenosis, subtle alterations in myocardial mechanics can be detected by speckle-tracking echocardiography before reduction of left ventricular ejection fraction (LVEF). METHODS: In this prospective study, 162 patients with aortic stenosis with an average aortic valve area of 0.7 ± 0.2 cm(2) and a mean LVEF of 60 ± 11% were included. Global longitudinal strain (GLS) and mechanical dispersion (SD of time from Q/R on the electrocardiogram to peak strain in 16 left ventricular segments) were assessed using echocardiography, and all-cause mortality (n = 37) was recorded during 37 ± 13 months of follow-up...
June 6, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28599825/left-ventricular-rotational-and-twist-mechanics-in%C3%A2-the-human-fetal-heart
#18
Ling Li, Mary Craft, Hao H Hsu, Ming Zhang, Berthold Klas, David A Danford, Shelby Kutty
BACKGROUND: The authors investigated left ventricular (LV) rotational indices, twist, and torsion in a large cohort of fetuses using two-dimensional speckle-tracking echocardiography. METHODS: Pregnant women (N = 102) were prospectively recruited for fetal two-dimensional speckle-tracking echocardiography. Because of variable fetal position, ventricular orientation was established using the location of the liver and LV position in relation to the right ventricle...
June 6, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28598119/-aortic-and-mitral-annuli-coupling-and-its-association-with-cardiac-function-in-patients-with-dilated-cardiomyopathy
#19
Yan-Ting Liu, Wen-Juan Bai, Qiu Xie, Li Rao
OBJECTIVES: To compare the mitral and aortic annuli excursion (AE) and aortomitral angle (AMA) variations between patients with and without dilated cardiomyopathy (DCM) using speckle tracking echocardiography (STE),and determine the role of annuli dynamics and coupling behaviors in the left ventricular function. METHODS: Thirty-five patients with DCM and thirty-five age and sex matched healthy adults underwent transthoracic echocardiographic examinations.In the parasternal long-axis view,the AE and AMA variations were measured using Philips QLAB 9...
November 2016: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28597735/early-changes-of-left-atrial-function-in-chronic-asymptomatic-alcoholics-by-two-dimensional-speckle-tracking-echocardiography
#20
Rui Xu, Runlan Luo, Bijun Tan, Tian Gan, Guangsen Li
Background Chronic excessive alcohol intake has been reported as a possible cause of dilated cardiomyopathy. Two-dimensional speckle-tracking echocardiography (2D-STE) is a novel method for the angle-independent and objective quantification of myocardial deformation. This study sought to assess left atrial function changes among alcoholics related to the duration of heavy drinking by 2D-STE. Methods We classified 92 asymptomatic alcoholics into mild, moderate and severe groups. Thirty age-matched controls were also recruited...
February 2017: Acta Cardiologica
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