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osteochondral allograft

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https://www.readbyqxmd.com/read/27922984/osteochondral-allografts-in-shoulder-surgical-procedures
#1
Nicholas M Capito, Brett D Owens, Seth L Sherman, Matthew J Smith
No abstract text is available yet for this article.
November 15, 2016: JBJS Reviews
https://www.readbyqxmd.com/read/27909660/osteochondral-proximal-tibial-and-lateral-meniscal-allograft-transplant
#2
Guillem Gonzalez-Lomas, Andrew P Dold, Daniel J Kaplan, David J Fralinger, Laith Jazrawi
Knee pain in young, active patients with meniscus-deficient knees and articular cartilage damage can present a challenge to treatment. Meniscal allograft transplantation (MAT) has shown good clinical results as treatment for meniscus deficiency; however, worse outcomes have been observed in patients with significant chondral damage. The development of chondral restorative techniques such as osteochondral allograft transplantation (OCA) has expanded the population of patients who may benefit from MAT. We present a case of proximal tibial osteochondral and lateral meniscal allograft transplant...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27896291/fresh-osteochondral-allograft-to-the-humeral-head-for-treatment-of-an-engaging-reverse-hill-sachs-lesion-technical-case-report-and-literature-review
#3
Loren O Black, Jia-Wei Kevin Ko, Samantha M Quilici, Dennis C Crawford
No abstract text is available yet for this article.
November 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/27893924/deciding-how-best-to-treat-cartilage-defects
#4
Lucy Oliver-Welsh, Justin W Griffin, Maximilian A Meyer, Matthew E Gitelis, Brian J Cole
The decision-making regarding and treatment of cartilage abnormalities requires a systematic approach. This article reviews the concepts and principles that guide the management of this complex problem. The precise incidence, demographics, and progression of cartilage lesions have not been clearly delineated. Pursuing a patient-centered approach that considers the available nonsurgical and surgical options remains the cornerstone of patient care. The importance of determining concomitant knee pathologies, the proper interpretation and implications of imaging findings, and an accurate determination of the intra-articular and subchondral findings represent the primary elements of the decision analysis...
November 1, 2016: Orthopedics
https://www.readbyqxmd.com/read/27871417/large-bm-intra-articular-allograft
#5
REVIEW
Joan R Williams, Michael E Brage
Posttraumatic tibiotalar arthritis is a challenging problem in young, active patients. Many of these patients do not want to pursue ankle arthrodesis after they fail conservative treatment measures, as they wish to preserve joint motion. Osteochondral shell allograft arthroplasty has been described as a reasonable alternative for treating these patients. The procedure itself is technically demanding; however, with improvements in surgical technique and adequate preoperative patient counseling, it provides improvement in ankle function and has good outcomes for most patients at long-term follow-up...
December 2016: Foot and Ankle Clinics
https://www.readbyqxmd.com/read/27863947/the-effects-of-low-dose-radiotherapy-on-fresh-osteochondral-allografts-an-experimental-study-in-rabbits
#6
Uğur Gönç, Mehmet Çetinkaya, Mesut Atabek
OBJECTIVE: The aim of this study was to investigate the effects of low-dose fractionated radiotherapy on cartilage degeneration after distal femoral fresh massive osteochondral allograft transplantation. METHODS: Twenty-four New Zealand White rabbits were divided into three groups of 8 rabbits each. All rabbits underwent distal femoral medial condyle fresh massive osteochondral allograft transplantation from California rabbits. The group 1 underwent transplantation without any preliminary process...
November 15, 2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27859554/evaluation-of-genipin-for-stabilization-of-decellularized-porcine-cartilage
#7
Steven Elder, Amanda Pinheiro, Christian Young, Preston Smith, Emily Wright
We speculate that an acellular osteochondral xenograft may be a good alternative to allografts for repair of focal articular cartilage lesions. In order to make a xenograft resistant to enzymatic degradation and to prevent a chronic immune response it may beneficial to stabilize it through crosslinking. The concept is analogous to treatment of porcine bioprosthetic heart valves with glutaraldehyde. The purpose of this study was to evaluate genipin, a natural crosslinking agent with low cytotoxicity, for stabilization of decellularized cartilage...
November 18, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27793804/osteochondral-allograft-donor-host-matching-by-the-femoral-condyle-radius-of-curvature
#8
Derek T Bernstein, Craig A O'Neill, Ryan S Kim, Hugh L Jones, Philip C Noble, Joshua D Harris, Patrick C McCulloch
BACKGROUND: Conventional osteochondral allograft (OCA) matching, requiring orthotopic, size-matched condyles, and narrow surgical time windows often prohibit timely transplantation. HYPOTHESIS: The femoral condyle radius of curvature (RoC) is an appropriate, isolated criterion for donor-host matching in fresh OCAs, potentially enhancing matching efficiency when compared with conventional matching techniques. STUDY DESIGN: Descriptive laboratory study...
October 28, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27769090/-treatment-of-osteochondral-lesions-in-the-ankle-a-guideline-from-the-group-clinical-tissue-regeneration-of-the-german-society-of-orthopaedics-and-traumatology-dgou
#9
M Aurich, D Albrecht, P Angele, C Becher, S Fickert, J Fritz, P E Müller, P Niemeyer, M Pietschmann, G Spahn, M Walther
Background: Osteochondral lesions (OCL) of the ankle are a common cause of ankle pain. Although the precise pathophysiology has not been fully elucidated, it can be assumed that a variety of factors are responsible, mainly including traumatic events such as ankle sprains. Advances in arthroscopy and imaging techniques, in particular magnetic resonance imaging (MRI), have improved the possibilities for the diagnosis of OCLs of the ankle. Moreover, these technologies aim at developing new classification systems and modern treatment strategies...
October 21, 2016: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/27751721/coronoid-reconstruction-with-an-osteochondral-radial-head-graft
#10
Enrico Bellato, Roberto Rotini, Alessandro Marinelli, Enrico Guerra, Shawn W O'Driscoll
BACKGROUND: Chronic coronoid deficiency can occur subsequent to coronoid fracture malunion/nonunion or to coronoid hypoplasia or dysplasia resulting from injury during development. Several surgical options have been described to treat this difficult condition, but results are equivocal. We hypothesized that a modified coronoid reconstruction using a radial head osteochondral graft could restore elbow stability and congruity and that a technique involving rigid internal fixation would promote graft union...
October 14, 2016: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/27742247/fresh-osteochondral-allograft-transplantation-for-osteochondritis-dissecans-of-the-capitellum-in-baseball-players
#11
Raffy Mirzayan, Michael J Lim
BACKGROUND: Osteochondritis dissecans (OCD) of the capitellum is a rare yet debilitating injury seen in young athletes. This is the first report in the literature describing fresh osteochondral allograft transplantation (FOCAT) to treat OCD of the capitellum. METHODS: Nine male baseball players (mean age, 15.3; range, 14-18 years), with OCD of the capitellum were treated with FOCAT. There were 6 pitchers and 3 position players. A ligament-sparing, mini-open approach was used...
November 2016: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/27688840/acute-delamination-of-commercially-available-decellularized-osteochondral-allograft-plugs-a-report-of-two-cases
#12
Ryan M Degen, Danielle Tetreault, Greg T Mahony, Riley J Williams
Articular cartilage injuries, and corresponding surgical procedures, are occurring with increasing frequency as identified by a review of recent surgical trends. Concerns have grown in recent years regarding the longevity of results following microfracture, with a shift toward cartilage restoration procedures in recent years. This case report describes 2 cases of acute failure following the use of commercially available osteochondral allograft plugs used for the treatment of osteochondral defects of the distal femur...
October 2016: Cartilage
https://www.readbyqxmd.com/read/27673714/in-vivo-cellular-infiltration-and-remodeling-in-a-decellularized-ovine-osteochondral-allograft
#13
Tyler Novak, Kateri Fites Gilliland, Xin Xu, Logan Worke, Aaron Ciesielski, Gert Breur, Corey P Neu
Interest in decellularized tissues has steadily gained as potential solutions for degenerative diseases and traumatic events, replacing sites of missing tissue, and providing the relevant biochemistry and microstructure for tissue ingrowth and regeneration. Osteoarthritis, a progressive and debilitating disease, is often initiated with the formation of a focal defect in the otherwise smooth surface of articular cartilage. Decellularized cartilage tissue, which maintains the structural complexity of the native extracellular matrix, has the potential to provide a clinically relevant solution to focal defects or large tissue damage, possibly even circumventing or complementing current techniques such as microfracture and mosaicplasty...
November 2016: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/27663035/a-comparison-of-the-outcomes-for-cartilage-defects-of-the-knee-treated-with-biologic-resurfacing-versus-focal-metallic-implants
#14
Cecilia Pascual-Garrido, Erika Daley, Nikhil N Verma, Brian J Cole
PURPOSE: To compare the results of focal metallic resurfacing with biologic procedures in patients more than 35 years of age with isolated, full thickness defects of the femoral condyle. METHODS: A total of 61 patients met the selection criteria resulting in 30 patients treated with biological procedures, including debridement, microfracture, osteochondral autograft transplantation, osteochondral allograft, and autologous chondrocyte implantation (BIO group), and 32 patients treated with focal metallic resurfacing (CAP group)...
September 20, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/27623866/results-and-functional-outcomes-of-structural-fresh-osteochondral-allograft-transfer-for-treatment-of-osteochondral-lesions-of-the-talus-in-a-highly-active-population
#15
Justin D Orr, John C Dunn, Kenneth A Heida, Nicholas A Kusnezov, Brian R Waterman, Philip J Belmont
INTRODUCTION: Structural fresh osteochondral allograft transfer is an appropriate treatment option for large osteochondral lesions of the talus (OLTs), specifically lesions involving the shoulder of the talus. Sparse literature exists regarding functional outcome following this surgery in high-demand populations. MATERIALS AND METHODS: Over a 2-year period, a single surgeon performed 8 structural allograft transfers for treatment of large OLTs in an active duty US military population...
September 13, 2016: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/27610699/radial-head-and-neck-allograft-for-comminute-irreparable-fracture-dislocations-of-the-elbow
#16
Salvatore Bisicchia, Cosimo Tudisco
Fracture-dislocations of the elbow can be difficult to treat, with unsatisfactory results in some cases. In general, it is preferable to preserve the fractured radial head when possible, but some patients present a unique treatment challenge because of extremely comminuted fractures and bone loss. In these cases, the only options available are radial head prosthesis or allograft. The authors present a case of a 45-year-old man with a fracture-dislocation of the left elbow that was treated with an allograft of the radial head and neck because of extreme comminution of the fracture...
November 1, 2016: Orthopedics
https://www.readbyqxmd.com/read/27593886/osteochondral-autograft-from-the-ipsilateral-femoral-head-by-surgical-dislocation-for-treatment-of-femoral-head-fracture-dislocation-a-case-report
#17
Yougun Won, Gi Soo Lee, Sang Bum Kim, Sun Joong Kim, Kyu Hyun Yang
As anatomical reduction of the articular surface of femoral head fractures and restoration of damaged cartilage are essential for good long-term results, many treatment options have been suggested, including fixation of the fracture using various surgical exposures and implants, as well as arthroscopic irrigation and debridement, bone marrow stimulating techniques, osteochondral allograft, autograft, and autogenous chondrocyte implantation. We report a case of osteochondral autograft harvested from its own femoral articular surface through surgical hip dislocation...
November 2016: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27590275/surgical-interventions-microfracture-drilling-mosaicplasty-and-allograft-transplantation-for-treating-isolated-cartilage-defects-of-the-knee-in-adults
#18
Guilherme C Gracitelli, Vinícius Y Moraes, Carlos Es Franciozi, Marcus V Luzo, João Carlos Belloti
BACKGROUND: Cartilage defects of the knee are often debilitating and predispose to osteoarthritis. Microfracture, drilling, mosaicplasty, and allograft transplantation are four surgical treatment options that are increasingly performed worldwide. We set out to examine the relative effects of these different methods. OBJECTIVES: To assess the relative effects (benefits and harms) of different surgical interventions (microfracture, drilling, mosaicplasty, and allograft transplantation) for treating isolated cartilage defects of the knee in adults...
September 3, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27589932/human-talar-and-femoral-cartilage-have-distinct-mechanical-properties-near-the-articular-surface
#19
Corinne R Henak, Keir A Ross, Edward D Bonnevie, Lisa A Fortier, Itai Cohen, John G Kennedy, Lawrence J Bonassar
Talar osteochondral lesions (OCL) frequently occur following injury. Surgical interventions such as femoral condyle allogeneic or autogenic osteochondral transplant (AOT) are often used to treat large talar OCL. Although AOT aims to achieve OCL repair by replacing damaged cartilage with mechanically matched cartilage, the spatially inhomogeneous material behavior of the talar dome and femoral donor sites have not been evaluated or compared. The objective of this study was to characterize the depth-dependent shear properties and friction behavior of human talar and donor-site femoral cartilage...
October 3, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27546173/osteochondral-allograft-transfer-for-treatment-of-osteochondral-lesions-of-the-talus-a-systematic-review
#20
Richard J VanTienderen, John C Dunn, Nicholas Kusnezov, Justin D Orr
PURPOSE: The purpose of this study is to present a systematic review of the literature regarding the use of fresh bulk osteochondral allograft transfer for treatment of large osteochondral lesions of the talus (OCLT) in an effort to characterize the functional outcomes, complications, and reoperation rates. METHODS: A search of the PubMed, CINAHL, Embase, and Cochrane Databases was performed between January 1, 1990, and March 1, 2016, and included all articles related to outcomes after fresh talar allograft transplantation for OCLT...
August 18, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
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