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https://www.readbyqxmd.com/read/29669004/effects-of-monochromatic-light-stimuli-during-embryogenesis-on-some-performance-traits-behavior-and-fear-responses-in-japanese-quails
#1
Kübra Melis Sabuncuoglu, Firdevs Korkmaz, Eser Kemal Gürcan, Dogan Narinç, Hasan Ersin Saml X
Lighting is crucial in poultry rearing and the subjects with light intensity, source, and color having been addressed in numerous studies. Numerous studies with monochromatic light from light-emitting diode (LED) bulbs have been reported. In the current study, fertile Japanese quail eggs were exposed to a dark environment (Control) or monochromatic green (560 nm) and blue (480 nm) lighting throughout incubation. There were no significant differences in hatch weight, hatchability, total embryonic mortality, hatch time, growth performance, and slaughter-carcass traits in the study (P > 0...
April 14, 2018: Poultry Science
https://www.readbyqxmd.com/read/29665012/wavelet-pressure-reactivity-index-a-validation-study
#2
Xiuyun Liu, Marek Czosnyka, Joseph Donnelly, Danilo Cardim, Manuel Cabeleira, Peter J Hutchinson, Xiao Hu, Peter Smielewski, Ken Brady
KEY POINTS: The brain is vulnerable to damage from too little or too much blood flow. A physiological mechanism called cerebral autoregulation (CA) exists to maintain stable blood flow even if cerebral perfusion pressure (CPP) is changing. A robust method for assessing CA is not yet available. There are still some problems with the traditional measure, the pressure reactivity index (PRx). We introduced a new method, wavelet transform method (wPRx) to assess CA using data from two sets of controlled hypotension experiments in piglets: One set with artificially manipulated ABP oscillations; the other group were spontaneous ABP waves...
April 17, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29658903/high-versus-low-peep-for-abdominal-surgery
#3
Alastair J Glossop, Antonio M Esquinas
No abstract text is available yet for this article.
January 2018: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29650311/an-object-oriented-computational-model-to-study-cardiopulmonary-hemodynamic-interactions-in-humans
#4
Chuong Ngo, Stephan Dahlmanns, Thomas Vollmer, Berno Misgeld, Steffen Leonhardt
BACKGROUND AND OBJECTIVE: This work introduces an object-oriented computational model to study cardiopulmonary interactions in humans. METHODS: Modeling was performed in object-oriented programing language Matlab Simscape, where model components are connected with each other through physical connections. Constitutive and phenomenological equations of model elements are implemented based on their non-linear pressure-volume or pressure-flow relationship. The model includes more than 30 physiological compartments, which belong either to the cardiovascular or respiratory system...
June 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29629848/setting-dead-at-zero-applying-scale-properties-to-the-qaly-model
#5
Bram Roudijk, A Rogier T Donders, Peep F M Stalmeier
INTRODUCTION: Scaling severe states can be a difficult task. First, the method of measurement affects whether a health state is considered better or worse than dead. Second, in discrete choice experiments, different models to anchor health states on 0 (dead) and 1 (perfect health) produce varying amounts of health states worse than dead. RESEARCH QUESTION: Within the context of the quality-adjusted life-year (QALY) model, this article provides insight into the value assigned to dead and its consequences for decision making...
April 1, 2018: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/29626267/different-ventilation-techniques-and-hemodynamic-optimization-to-maintain-regional-cerebral-oxygen-saturation-rsco-2-during-laparoscopic-bariatric-surgery-a-prospective-randomized-interventional-study
#6
Osama M Asaad
PURPOSE: The purpose of this study was to assess the changes in regional cerebral oxygen saturation (rScO2 ) in response to different ventilation strategies: inspired oxygen concentration (FiO2 ), end-tidal carbon dioxide (EtCO2 ), and positive end expiratory pressure (PEEP) in addition to optimizing mean arterial pressure (MAP) in obese patients subjected to laparoscopic bariatric surgery in the reverse trendelenburg position. METHODS: 50 obese patients were randomly assigned into one of two groups...
April 6, 2018: Journal of Anesthesia
https://www.readbyqxmd.com/read/29606090/application-of-intraoperative-lung-protective-ventilation-varies-in-accordance-with-the-knowledge-of-anaesthesiologists-a-single-centre-questionnaire-study-and-a-retrospective-observational-study
#7
Seung Hyun Kim, Sungwon Na, Woo Kyung Lee, Hyunwoo Choi, Jeongmin Kim
BACKGROUND: The benefits of lung-protective ventilation (LPV) with a low tidal volume (6 mL/kg of ideal body weight [IBW]), limited plateau pressure (< 28-30 cm H2 O), and appropriate positive end-expiratory pressure (PEEP) in patients with acute respiratory distress syndrome have become apparent and it is now widely adopted in intensive care units. Recently evidence for LPV in general anaesthesia has been accumulated, but it is not yet generally applied by anaesthesiologists in the operating room...
April 2, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29600021/higher-vs-lower-peep-in-ards-just-one-part-of-the-whole
#8
EDITORIAL
Silvia Coppola, Sara Froio, Davide Chiumello
No abstract text is available yet for this article.
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29596015/continuous-negative-abdominal-pressure-mechanism-of-action-and-comparison-with-prone-position
#9
Takeshi Yoshida, Doreen Engelberts, Gail Otulakowski, Bhushan Katira, Niall D Ferguson, Laurent Brochard, Marcelo B P Amato, Brian P Kavanagh
We recently reported that continuous negative abdominal pressure (CNAP) could recruit dorsal atelectasis in experimental lung injury, and that oxygenation improved at different transpulmonary pressure values compared with increases in airway pressure (31). The mechanism of recruitment with CNAP is uncertain; and, its impact compared with a commonly proposed alternative approach to recruitment -prone positioning- is not known. We hypothesized that CNAP recruits lung by decreasing the vertical Ppl gradient (i...
March 29, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29595843/reduction-responsive-amphiphilic-polymeric-prodrugs-of-camptothecin-polyphosphoester-for-cancer-chemotherapy
#10
Hua Jin, Mo Sun, Leilei Shi, Xinyuan Zhu, Wei Huang, Deyue Yan
As one of the promising prodrug strategies, amphiphilic polymeric prodrugs can be constructed by conjugating some small molecular hydrophobic anticancer drugs onto a hydrophilic biodegradable and biocompatible polymer, which further self-assembles into nanoparticles with controllable drug loading. Here, a biocompatible and biodegradable polyphosphoester and a broad-spectrum anticancer drug camptothecin (CPT) were selected as model compounds. We first designed and synthesized a novel cyclic phosphoester monomer (CPTSP) containing a disulfide bond linker and CPT as a side group...
March 29, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29589765/diaphragm-remodeling-during-application-of-peep-a-case-of-normal-physiologic-adaptation-gone-awry
#11
Basil J Petrof, Catherine S Sassoon
No abstract text is available yet for this article.
March 28, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29578749/positive-end-expiratory-pressure-ventilation-induces-longitudinal-atrophy-in-diaphragm-fibers
#12
Johan Lindqvist, Marloes van den Berg, Robbert van der Pijl, Pleuni E Hooijman, Albertus Beishuizen, Judith Elshof, Monique de Waard, Armand Girbes, Angelique Spoelstra-de Man, Zhong-Hua Shi, Charissa van den Brom, Sylvia Bogaards, Shengyi Shen, Joshua Strom, Henk Granzier, Jeroen Kole, René J P Musters, Marinus A Paul, Leo M A Heunks, Coen A C Ottenheijm
RATIONALE: Diaphragm weakness in critically ill patients prolongs ventilator dependency and duration of hospital stay, and increases mortality and health care costs. The mechanisms underlying diaphragm weakness include cross-sectional fiber atrophy and contractile protein dysfunction, but whether additional mechanisms are at play is unknown. OBJECTIVES: To test the hypothesis that mechanical ventilation with positive end-expiratory pressure (PEEP) induces longitudinal atrophy by displacing the diaphragm in caudal direction and reducing the length of fibers...
March 26, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29576128/non-invasive-positive-pressure-ventilation-with-positive-end-expiratory-pressure-counteracts-inward-air-leaks-during-preoxygenation-a-randomised-crossover-controlled-study-in-healthy-volunteers
#13
J-L Hanouz, F Le Gall, J-L Gérard, N Terzi, H Normand
BACKGROUND: During preoxygenation, the lack of tight fit between the mask and the patient's face results in inward air leak preventing effective preoxygenation. We hypothesized that non-invasive positive-pressure ventilation and positive end-expiratory pressure (PEEP) could counteract inward air leak. METHODS: Healthy volunteers were randomly assigned to preoxygenated through spontaneous breathing without leak (SB), spontaneous breathing with a calibrated air leak (T-shaped piece between the mouth and the breathing system; SB-leak), or non-invasive positive inspiratory pressure ventilation (inspiratory support +6 cm H2 O; PEEP +5 cm H2 O) with calibrated leak (PPV-leak)...
April 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29576127/evaluation-of-lung-and-chest-wall-mechanics-during-anaesthesia-using-the-peep-step-method
#14
P Persson, O Stenqvist, S Lundin
BACKGROUND: Postoperative pulmonary complications are common. Between patients there are differences in lung and chest wall mechanics. Individualised mechanical ventilation based on measurement of transpulmonary pressures would be a step forward. A previously described method evaluates lung and chest wall mechanics from a change of ΔPEEP and calculation of change in end-expiratory lung volume (ΔEELV). The aim of the present study was to validate this PEEP-step method (PSM) during general anaesthesia by comparing it with the conventional method using oesophageal pressure (PES) measurements...
April 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29576103/analysing-tidal-volumes-early-after-a-positive-end-expiratory-pressure-increase-a-new-way-to-determine-optimal-peep-in-the-operating-theatre
#15
EDITORIAL
S Shaefi, M Eikermann
No abstract text is available yet for this article.
April 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29563678/heterogeneity-of-o-blood-group-in-india-peeping-through-the-window-of-molecular-biology
#16
Harita Gogri, Sabita Ray, Snehal Agrawal, S Aruna, Kanjaksha Ghosh, Ajit Gorakshakar
BACKGROUND: Molecular genotyping of ABO blood group system has identified more than 60 "O" group alleles based on the single-nucleotide polymorphisms present in the ABO gene. Heterogeneity of O group alleles has been observed in various countries from South America, Europe, Middle East, and Asia. India is a vast country with more than 1300 million population which is divided into various ethnic and tribal groups. However, very little is known about the heterogeneity of O alleles in Indians...
January 2018: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/29561278/protective-ventilation-during-anaesthesia-reduces-major-postoperative-complications-after-lung-cancer-surgery-a-double-blind-randomised-controlled-trial
#17
Emmanuel Marret, Raphael Cinotti, Laurence Berard, Vincent Piriou, Jacques Jobard, Benoit Barrucand, Dragos Radu, Samir Jaber, Francis Bonnet
BACKGROUND: Thoracic surgery for lung resection is associated with a high incidence of postoperative pulmonary complications. Controlled ventilation with a large tidal volume has been documented to be a risk factor for postoperative respiratory complications after major abdominal surgery, whereas the use of low tidal volumes and positive end-expiratory pressure (PEEP) has a protective effect. OBJECTIVE: To evaluate the effects of ventilation with low tidal volume and PEEP on major complications after thoracic surgery...
March 19, 2018: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29559484/extracorporeal-membrane-oxygenation-ecmo-for-near-fatal-asthma-refractory-to-conventional-ventilation
#18
Usman Maqsood, Nehal Patel
We describe a case of near-fatal asthma, treated successfully by initiation of extracorporeal membrane oxygenation (ECMO). A 29-year-old woman, known asthmatic on steroid inhalers, inhaled/nebulised bronchodilators, long-term oral prednisolone, theophylline and montelukast, presented with acute shortness of breath. She deteriorated following initial treatment with nebulised bronchodilators and magnesium sulfate requiring intubation and mechanical ventilation. Severe bronchospasm ensued following mechanical ventilation and peak airway pressures remained at 55 cm H2 O with intrinsic positive end expiratory pressure(PEEP) of 14 cm H2 O...
March 20, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29546563/a-high-flow-nasal-cannula-system-with-relatively-low-flow-effectively-washes-out-co-2-from-the-anatomical-dead-space-in-a-sophisticated-respiratory-model-made-by-a-3d-printer
#19
Yu Onodera, Ryo Akimoto, Hiroto Suzuki, Masayuki Okada, Masaki Nakane, Kaneyuki Kawamae
BACKGROUND: Although clinical studies of the high-flow nasal cannula (HFNC) and its effect on positive end-expiratory pressure (PEEP) have been done, the washout effect has not been well evaluated. Therefore, we made an experimental respiratory model to evaluate the respiratory physiological effect of HFNC. METHODS: An airway model was made by a 3D printer using the craniocervical 3D-CT data of a healthy 32-year-old male. CO2 was infused into four respiratory lung models (normal-lung, open- and closed-mouth models; restrictive- and obstructive-lung, open-mouth models) to maintain the partial pressure of end-tidal CO2 (PET CO2 ) at 40 mmHg...
March 15, 2018: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/29538440/impact-of-large-volume-paracentesis-on-respiratory-parameters-including-transpulmonary-pressure-and-on-transpulmonary-thermodilution-derived-hemodynamics-a-prospective-study
#20
Ulrich Mayr, Eugen Karsten, Tobias Lahmer, Sebastian Rasch, Philipp Thies, Benedikt Henschel, Gerrit Fischer, Roland M Schmid, Wolfgang Huber
INTRODUCTION: Appropriate mechanical ventilation and prevention of alveolar collaps is mainly dependent on transpulmonary pressure TPP. TPP is assessed by measurement of esophageal pressure EP, largely influenced by pleural and intraabdominal pressure IAP. Consecutively, TPP-guided ventilation might be particularly useful in patients with high IAP. This study investigates the impact of large volume paracentesis LVP on TPP, EP, IAP as well as on hemodynamic and respiratory function in patients with liver cirrhosis and tense ascites...
2018: PloS One
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