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https://www.readbyqxmd.com/read/29331289/titanium-scaffolding-an-innovative-modality-for-salvage-of-failed-first-ray-procedures
#1
Natalie Coriaty, Katherine Pettibone, Nicholas Todd, Shannon Rush, Ryan Carter, Colin Zdenek
Shortening of the first ray is a potential complication associated with first metatarsal procedures. Correction of this deformity conventionally has required the use of a tricortical bone graft to lengthen the bone. Graft complications, including donor site morbidity, poor graft stability, and graft resorption, have revealed a need for an alternative procedure. The present report shows that titanium cage scaffolding has lower extremity applications beyond its previous uses in the ankle and spine. Two patients underwent surgical correction for failed first ray procedures using a titanium cage apparatus with a calcaneal autograft and other biologic agents...
January 11, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29329902/impact-of-vertical-and-horizontal-malrotation-on-measurements-of-anteroposterior-radiographs-of-the-scapula-need-for-standardized-images-in-modern-omometry
#2
Samy Bouaicha, Armando Hoch, Thorsten Jentzsch, Beat K Moor
BACKGROUND: An increasing number of parameters measured on anteroposterior radiographs are used for the evaluation of the bony geometry of the scapula. Inhomogeneous acquisition of images is common because of the lack of standardization in radiographic positioning. Images with malrotation around the horizontal axis of the scapula are particularly frequent. We hypothesized that malrotated images would result in large variations in measured radiographic parameters and that image standardization using qualitative and semiquantitative "omometric" criteria would decrease these variations in measurements...
January 9, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29323942/comparison-of-juvenile-allogenous-articular-cartilage-and-bone-marrow-aspirate-concentrate-versus-microfracture-with-and-without-bone-marrow-aspirate-concentrate-in-arthroscopic-treatment-of-talar-osteochondral-lesions
#3
Sydney C Karnovsky, Bridget DeSandis, Amgad M Haleem, Carolyn M Sofka, Martin O'Malley, Mark C Drakos
BACKGROUND: The purpose of this study was to compare the functional and radiographic outcomes of patients who received juvenile allogenic chondrocyte implantation with autologous bone marrow aspirate (JACI-BMAC) for treatment of talar osteochondral lesions with those of patients who underwent microfracture (MF). METHODS: A total of 30 patients who underwent MF and 20 who received DeNovo NT for JACI-BMAC treatment between 2006 and 2014 were included. Additionally, 17 MF patients received supplemental BMAC treatment...
January 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29322970/minimally-invasive-transforaminal-lumbar-interbody-fusion-using-bone-cement-augmented-pedicle-screws-for-lumbar-spondylolisthesis-in-patients-with-osteoporosis-case-series-and-review-of-literature
#4
Venkata Ramesh Chandra Vemula, Bodapati Chandramowliswara Prasad, M A Jagadeesh, Jayachandar Vuttarkar, Sanjeev Kumar Akula
BACKGROUND: Instrumentation in patients with osteoporosis is challenging. Bone cement-augmented fenestrated pedicle screw fixation is a new procedure for fixation in the osteoporotic bone; and, applying minimally invasive techniques to the above is a challenging and novel concept. AIMS: To evaluate the clinical and radiological outcome of minimally invasive spine surgery transforaminal lumbar interbody fusion (MIS-TLIF) in patients with spondylolisthesis and poor bone quality, performed with rigid instrumentation using bone cement [poly(methylmethacrylate)]-augmented fenestrated pedicle screws...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29320219/modified-latarjet-without-capsulolabral-repair-in-rugby-players-with-recurrent-anterior-glenohumeral-instability-and-significant-glenoid-bone-loss
#5
Maximiliano Ranalletta, Luciano A Rossi, Agustin Bertona, Ignacio Tanoira, Ignacio Alonso Hidalgo, Gastón D Maignon, Santiago L Bongiovanni
BACKGROUND: The optimal management of recurrent anterior shoulder instability with significant glenoid bone loss in high-demand collision athletes remains a challenge. PURPOSE: To analyze the time to return to sport, clinical outcomes, and recurrences following a modified Latarjet procedure without capsulolabral repair in rugby players with recurrent anterior shoulder instability and significant glenoid bone loss. STUDY DESIGN: Case series; Level of evidence, 4...
January 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29318781/phosphonate-functionalized-poly-%C3%AE-amino-ester-macromers-as-potential-biomaterials
#6
Ece Akyol, Mirac Tatliyuz, Fatma Demir Duman, Melek Naz Guven, Havva Yagci Acar, Duygu Avci
Biodegradability, hemocompatibility, resistance to protein adsorption, and strong interactions with hydroxyapatite (HAP)-based tissues such as dentin, enamel, and bone are important properties of phosphorus-containing biomaterials. Here, novel phosphonate-functionalized poly(β-amino ester) (PBAE) macromers are synthesized through aza-Michael addition of various diacrylates [1,6-hexanediol diacrylate (HDDA), poly(ethylene glycol) diacrylate (PEGDA, Mn =575), 1,4-butanediol diacrylate (BDDA), 1,6-hexanediol ethoxylate diacrylate (HDEDA) and triethylene glycol diacrylate (TEGDA)] and a phosphonate-containing primary amine (diethyl 2-aminoethylphosphonate, A1) efficiently without any catalyst; where replacement of A1 with propyl amine (PA) served as control...
January 10, 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29310386/comparison-the-clinical-outcomes-and-complications-of-high-viscosity-versus-low-viscosity-in-osteoporotic-vertebral-compression-fractures
#7
Zhao Guo, Wei Wang, Wen-Shan Gao, Fei Gao, Hui Wang, Wen-Yuan Ding
To compare the clinical outcomes and complications of high viscosity and low viscosity bone cement percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCF).From September 2009 to September 2015, 100 patients with OVCF were randomly divided into 2 groups: group H, using high viscosity cement (n = 50) or group L, using low viscosity cement (n = 50). The clinical outcomes were assessed by the visual analog scale (VAS), Oswestry Disability Index (ODI), kyphosis Cobb angle, vertebral height, and complications...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29305100/clinical-outcomes-of-minimally-invasive-open-reduction-and-internal-fixation-by-screw-and-washer-for-displaced-greater-tuberosity-fracture-of-the-humerus
#8
Tae-Hwan Yoon, Chong-Hyuk Choi, Yun-Rak Choi, Jong-Taek Oh, Yong-Min Chun
BACKGROUND: The purpose of this study was to investigate clinical and radiologic outcomes of open reduction and internal fixation with a screw and washer for a displaced greater tuberosity fracture of the proximal humerus through a small incision. METHODS: We retrospectively reviewed 29 patients who underwent open reduction and internal fixation with a screw and washer for a greater tuberosity fracture of the proximal humerus. After surgery, the patients were immobilized in a brace for 4 weeks...
January 3, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29303982/curcumin-analog-dk1-induces-apoptosis-in-human-osteosarcoma-cells-in-vitro-through-mitochondria-dependent-signaling-pathway
#9
Muhammad Nazirul Mubin Aziz, Yazmin Hussin, Nurul Fattin Che Rahim, Noraini Nordin, Nurul Elyani Mohamad, Swee Keong Yeap, Chean Yeah Yong, Mas Jaffri Masarudin, Yoke Kqueen Cheah, Nadiah Abu, Muhammad Nadeem Akhtar, Noorjahan Banu Alitheen
Osteosarcoma is one of the primary malignant bone tumors that confer low survival rates for patients even with intensive regime treatments. Therefore, discovery of novel anti-osteosarcoma drugs derived from natural products that are not harmful to the normal cells remains crucial. Curcumin is one of the natural substances that have been extensively studied due to its anti-cancer properties and is pharmacologically safe considering its ubiquitous consumption for centuries. However, curcumin suffers from a poor circulating bioavailability, which has led to the development of a chemically synthesized curcuminoid analog, namely (Z)-3-hydroxy-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one (DK1)...
January 5, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29301187/treatment-outcomes-of-gonadotropin-releasing-hormone-agonist-in-obese-girls-with-central-precocious-puberty
#10
Hye Ryun Kim, Hyo-Kyoung Nam, Young-Jun Rhie, Kee-Hyoung Lee
PURPOSE: This study investigated the influence of obesity on the clinical course and effect of gonadotropin-releasing hormone analog (GnRHa) treatment in girls with central precocious puberty (CPP). METHODS: Medical records of 182 girls with CPP treated with GnRHa were reviewed. They were divided into 2 groups: normal weight (n=108) and overweight/obesity (n=74). Chronological age (CA), bone age (BA), difference between BA and CA (BA-CA), standard deviation score (SDS) of height, body mass index (BMI), predicted adult height (PAH), and laboratory findings were compared at baseline, after 1 year, and at the end of GnRHa treatment in both groups...
December 2017: Annals of Pediatric Endocrinology & Metabolism
https://www.readbyqxmd.com/read/29298726/effects-of-bone-marrow-aspirate-concentrate-and-platelet-rich-plasma-on-patients-with-partial-tear-of-the-rotator-cuff-tendon
#11
Sang Jun Kim, Eun Kyung Kim, Sun Jeong Kim, Da Hyun Song
BACKGROUND: We compared the clinical course of rotator cuff tears between rotator cuff exercise and bone marrow aspirate concentration (BMAC)-platelet rich plasma (PRP) injection to identify the therapeutic effects of BMAC-PRP on partial tear of the rotator cuff tendon. METHODS: Twenty-four patients with partial tear of the rotator cuff tendon participated in this study. Twelve patients underwent extraction of BMACs and PRP and received the injection of BMAC-PRP at the tear site under ultrasound guidance...
January 3, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29298277/impact-of-magnetic-resonance-imaging-on-treatment-related-decision-making-for-osteoporotic-vertebral-compression-fracture-a-prospective-randomized-trial
#12
Cong Jin, Guojian Xu, Dong Weng, Minghua Xie, Yu Qian
BACKGROUND The aim of this study was to analyze the impact and usefulness of characteristic signal change of a linear black signal on magnetic resonance imaging (MRI) on treatment-related decision making. MATERIAL AND METHODS Forty-one patients with a linear black signal on MRI were enrolled in this prospective study. They were randomly divided into the percutaneous kyphoplasty (PKP) group (n=24) and the conservative treatment group (n=17). Clinical measures, including visual analog scale (VAS) and short-form 36 (SF-36) questionnaire, were analyzed...
January 3, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29298102/deer-bone-extract-supplementation-for-mild-to-moderate-knee-osteoarthritis-symptoms-a-randomized-double-blind-placebo-controlled-trial
#13
Dongseok Shin, Eun Ae Kim, Yoon Young Kim, Min Seo Kim, Jong Hoon Kim, Chang Won Ahn, Soo-Hyun Park, Ki Won Lee, Jae Hwa Kim, Ji Yeon Kim
In this randomized, double-blind, placebo-controlled study, we evaluated the efficacy of deer bone extract (DBE) in participants with knee osteoarthritis (OA). We enrolled 50 participants aged 50-70 years, having knee OA with a Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score ≥5.0. The participants were assigned to the placebo or DBE group (550 mg/day) for 12 weeks. The outcome measures were as follows: pain score on the visual analog scale (VAS); WOMAC score; and blood and urine biomarkers...
January 3, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29287060/clinical-outcome-of-total-knee-arthroplasty-performed-using-patient-specific-cutting-guides
#14
Murat Çalbıyık
BACKGROUND Patient-specific instruments have recently gained attention for ensuring the accuracy of osteotomy and correct alignment in total knee arthroplasty (TKA). We aimed to report our experience with TKA performed by using CT-based 3D model of cutting guides in our clinic. MATERIAL AND METHODS A total of 36 patients (mean age, 67.58±8.46 years; 24 females, 12 males) who underwent TKA with 3D patient-specific cutting guides in our clinic were included in the study. Differences between preoperatively planned bone resections and actual bone resections were calculated...
December 29, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29285560/anterior-controllable-antidisplacement-and-fusion-surgery-for-the-treatment-of-multilevel-severe-ossification-of-the-posterior-longitudinal-ligament-with-myelopathy-preliminary-clinical-results-of-a-novel-technique
#15
Jingchuan Sun, Jiangang Shi, Ximing Xu, Yong Yang, Yuan Wang, Qingjie Kong, Haisong Yang, Yongfei Guo, Dan Han, Jingjing Jiang, Guodong Shi, Wen Yuan, Lianshun Jia
PURPOSE: Although anterior and posterior decompression surgery are both reported to treat patients with myelopathy caused by ossification of the posterior longitudinal ligament (OPLL). The surgical strategy of the disease is still controversial when the OPLL is multilevel and severe. This present study reports the preliminary clinical results of a novel technique named anterior controllable antidisplacement and fusion (ACAF) for the treatment of multilevel-severe OPLL with myelopathy...
December 28, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29284573/case-report-late-reconstruction-of-the-land-mine-injured-heel-with-an-osteomyocutaneous-composite-fibular-flap
#16
Harun Yasin Tuzun, Mustafa Kurklu, Yalcin Kulahci, Selim Turkkan, Arsen Arsenishvili
The heel comprises the epidermis, minimal subcutaneous tissue, a dense septum, and the calcaneus. Injury to any of these structures can impair the ability to walk. The soft tissue or calcaneal bone can be injured by trauma. Injuries incurred in war are usually high-energy traumas caused by weapons such as rifles, rockets, and land mines. Such injuries can be life threatening and involve the loss of tissue, including skin, soft tissue, bone, and neurovascular tissue. Two main treatment protocols are used for such injuries with large tissue defects: amputation and reconstruction...
December 25, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29274286/the-prevention-of-latanoprost-on-osteoclastgenesis-in-vitro-and-lipopolysaccharide-induced-murine-calvaria-osteolysis-in-vivo
#17
Xing Xu, Yufei Yan, Zhuochao Liu, Jin Qi, Niandong Qian, Hanbing Zhou, Qi Zhou, Tianqi Wang, Ping Huang, Lei Guo, Min Jiang, Lianfu Deng
Identification of agents that inhibit osteoclast formation and function is important for the treatment of osteolytic diseases which feature excessive osteoclast formation and bone resorption. Latanoprost (LTP), an analog of prostaglandin F2α, is a medication which works to lower pressure inside the eyes. Prostaglandin F2α was reported to regulate bone metabolism, however the effect of LTP in osteoclastogenesis is still unknown. Here, we found that LTP suppressed RANKL-induced osteoclastogenesis in a dose-dependent manner as illustrated by TRAP activity and TRAP staining...
December 23, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29260299/-updates-to-the-who-classification-of-bone-tumours
#18
REVIEW
G Jundt
The fourth edition of the WHO Classification of Soft Tissue and Bone Tumours, published in 2013, extends the approach to describe genetics and pathology of these tumours in the context of epidemiological, clinical and imaging data, which was adopted in the third edition. Added are a few new entities, reclassifications and renamings. The most important point, also of clinical relevance and with consequences for treatment, is the introduction of a stratification of bone tumours based on their biological behaviour into three groups (benign, intermediate, malignant) in analogy to soft tissue tumours...
December 19, 2017: Der Pathologe
https://www.readbyqxmd.com/read/29248257/forearm-as-a-valuable-source-of-vascularized-bone-graft-for-the-distal-humerus
#19
Reza Shahryar Kamrani, Leila Farhadi, Amir Reza Farhoud
BACKGROUND: The nonunion of a distal humeral fracture is a challenging complication. Our aim was to assess the results of the application of pedicled bone flap to treat this problem. METHODS: There were 6 men and 3 women with delayed union or nonunion of the distal humerus treated by 10 procedures of rigid fixation plus radial bone forearm or posterior interosseous bone flaps. A locking plate was applied for fixation in 4 patients and a pin and plate for 5 patients...
December 14, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29241695/percutaneous-full-endoscopic-anterior-transcorporeal-procedure-for-cervical-disc-herniation-a-novel-procedure-and-early-follow-up-study
#20
Qian Du, Xin Wang, Jian-Pu Qin, Thor Friis, Wei-Jun Kong, Yu-Qiang Cai, Jun Ao, Hao Xu, Wen-Bo Liao
OBJECTIVES: To describe the surgical technique of percutaneous full-endoscopic anterior transcorporeal cervical discectomy (PEATCD) in detail and report the clinical outcomes and radiological changes in patients with cervical intervertebral disc herniation (CIVDH). METHODS: A novel procedure, PEATCD, was performed on 36 patients with CIVDH between June 2015 and June 2016. A retrospective study of these patients was carried out over a follow-up period of 12-24 months...
December 11, 2017: World Neurosurgery
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