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https://www.readbyqxmd.com/read/29161699/patterns-of-detection-of-fetal-posterior-fossa-anomalies-analysis-of-81-cases-in-the-second-half-of-gestation
#1
Stéphanie Friszer, Ferdinand Dhombres, Eléonore Blondiaux, Marie-Laure Moutard, Catherine Garel, Jean-Marie Jouannic
OBJECTIVE: To establish which characteristics of fetal ultrasound screening lead to the diagnosis of posterior fossa (PF) anomalies. METHODS: A total of 81 fetuses with PF anomalies diagnosed after dedicated neuroimaging between July 1, 2007, and January 1, 2013, were included. The ultrasound characteristics of the fetal cerebellum categorized according to an anatomical approach to the PF, associated fetal anomalies, gestational age at diagnosis, and the potential benefits from systematic measurement of the transverse cerebellar diameter (TCD) were analyzed...
November 21, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/29161466/treating-early-undifferentiated-arthritis-a-systematic-review-and-meta-analysis-of-direct-and-indirect-trial-evidence
#2
Maria A Lopez-Olivo, Voke Kakpovbia-Eshareturi, Jude des Bordes, Andrea Barbo, Robin Christensen, Maria E Suarez-Almazor
OBJECTIVE: We undertook a systematic review and meta-analysis of direct and indirect trial evidence to evaluate the efficacy of treatments for patients with undifferentiated arthritis (UA). METHODS: We searched four electronic databases from inception to January 2016, clinicaltrials. gov, and bibliographies of relevant articles. Two reviewers independently screened and evaluated the studies. The primary outcome was development of rheumatoid arthritis (RA). RESULTS: Nine studies were included...
November 21, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29161458/proton-pump-inhibitors-for-functional-dyspepsia
#3
REVIEW
Maria Ines Pinto-Sanchez, Yuhong Yuan, Ahmed Hassan, Premysl Bercik, Paul Moayyedi
BACKGROUND: Functional dyspepsia (FD or non-ulcer dyspepsia) is defined as continuous or frequently recurring epigastric pain or discomfort for which no organic cause can be found. Acid suppressive therapy, including proton pump inhibitors (PPIs), has been proposed as a therapeutic option in FD, but its efficacy remains controversial. While PPIs are generally considered safe and well tolerated, they have been associated with adverse events, especially in the long term. For this reason, decisions on whether to initiate or continue PPI therapy should be made based on an appropriate clinical indication...
November 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29161419/incidence-of-postoperative-atrial-fibrillation-recurrence-in-patients-discharged-in-sinus-rhythm-after-cardiac-surgery-a-systematic-review-and-meta-analysis
#4
Nicole Lowres, Georgina Mulcahy, Kai Jin, Robyn Gallagher, Lis Neubeck, Ben Freedman
Postoperative atrial fibrillation (POAF) is associated with increased stroke risk and mortality post-discharge. POAF is often considered transient; however, recurrence is likely under-recognized as symptoms are an unreliable guide. Surveillance post-discharge may identify asymptomatic POAF recurrences in patients discharged in sinus rhythm. Therefore, we performed a systematic review and meta-analysis of studies investigating POAF recurrence post-discharge, in patients with new-onset POAF following cardiac surgery who reverted to sinus rhythm prior to discharge...
November 17, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29161335/shoulder-complaints-in-wheelchair-athletes-a-systematic-review
#5
Omar W Heyward, Riemer J K Vegter, Sonja de Groot, Lucas H V van der Woude
BACKGROUND: In recent years the popularity of disabled sports and competition among disabled athletes has grown considerably. With this rise in exposure of, and participation in wheelchair sports comes an increase in related stressors, including musculoskeletal load. External mechanical loading may increase the risk of shoulder complaints. The objective of this literature review was to 1) identify and describe the prevalence and/or incidence of shoulder complaints in wheelchair athletes in the literature, to 2) examine the factors and underlying mechanisms that could be potentially involved, and 3) provide some insights into the development of preventative measures...
2017: PloS One
https://www.readbyqxmd.com/read/29161276/association-between-diabetes-mellitus-and-active-tuberculosis-a-systematic-review-and-meta-analysis
#6
Rami H Al-Rifai, Fiona Pearson, Julia A Critchley, Laith J Abu-Raddad
The burgeoning epidemic of diabetes mellitus (DM) is one of the major global health challenges. We systematically reviewed the published literature to provide a summary estimate of the association between DM and active tuberculosis (TB). We searched Medline and EMBASE databases for studies reporting adjusted estimates on the TB-DM association published before December 22, 2015, with no restrictions on region and language. In the meta-analysis, adjusted estimates were pooled using a DerSimonian-Laird random-effects model, according to study design...
2017: PloS One
https://www.readbyqxmd.com/read/29161218/the-impact-of-dementia-on-relationships-intimacy-and-sexuality-in-later-life-couples-an-integrative-qualitative-analysis-of-existing-literature
#7
Kristen Holdsworth, Marita McCabe
OBJECTIVES: The onset and progression of dementia can have a profound effect on the couple dyad. The aim of this systematic review was to analyze the literature investigating the impact of dementia on the relationships, intimacy, and sexuality in older couples. METHODS: A systematic literature search was conducted in May 2016 for relevant research articles. Five databases were searched: Web of Science, PsycINFO, MedLine, Scopus and CINAHL. The reference lists of articles included in the review were screened along with the reference list of other relevant reviews...
September 15, 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/29161138/autologous-matrix-induced-chondrogenesis-a-systematic-review-of-the-clinical-evidence
#8
Liang Gao, Patrick Orth, Magali Cucchiarini, Henning Madry
BACKGROUND: The addition of a type I/III collagen membrane in cartilage defects treated with microfracture has been advocated for cartilage repair, termed "autologous matrix-induced chondrogenesis" (AMIC). PURPOSE: To examine the current clinical evidence regarding AMIC for focal chondral defects. STUDY DESIGN: Systematic review. METHODS: A systematic review was performed by searching PubMed, ScienceDirect, and Cochrane Library databases...
November 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29160924/accelerated-untargeted-metabolomics-analysis-of-cutaneous-t-cell-lymphoma-reveal-metabolic-shifts-in-plasma-and-tumor-adjacent-skins-of-xenograft-mice
#9
Yunchen Le, Xiaoyan Shen, Hongyan Kang, Qizheng Wang, Kejia Li, Jie Zheng, Yunqiu Yu
Cutaneous T-cell lymphoma (CTCL) is a heterogeneous group of skin-homing T-cell neoplasms. Clinical management is stage based but diagnosis and prognosis could be extremely challenging. The presented study aims to explore the metabolic profiling of CTCL by an accelerated untargeted metabolomics data analysis tool "mummichog" to facilitate the discoveries of potential biomarkers for clinical early-stage diagnosis, prognosis and treatments in CTCL. Ultra-high-performance liquid chromatography-quadrupole time-of-flight (UHPLC-QTOF) based untargeted metabolomics were conducted on the skin and plasma of CTCL mice...
November 21, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/29160718/social-and-leisure-activity-profiles-and-well-being-among-the-older-adults-a-longitudinal-study
#10
Joulain Michèle, Martinent Guillaume, Taliercio Alain, Bailly Nathalie, Ferrand Claude, Gana Kamel
OBJECTIVES: Studies highlight the beneficial effects of social and leisure activities on the well-being of aging people. Our aims were: to investigate activity profiles among older adults living in their own homes, to highlight potential changes in profiles over a period of five years and to examine effects of differences between these profiles on well-being variables. METHODS: Three waves were considered in this longitudinal study, with 550, 410 and 374 people (76, 79, 82 years on average), respectively...
November 21, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29160536/use-of-the-ishikawa-diagram-in-a-case-control-analysis-to-assess-the-causes-of-a-diffuse-lamellar-keratitis-outbreak
#11
Luis Henrique Lira, Flávio E Hirai, Marivaldo Oliveira, Waldir Portellinha, Eliane Mayumi Nakano
PURPOSE: To identify the causes of a diffuse lamellar keratitis (DLK) outbreak using a systematic search tool in a case-control analysis. METHODS: An Ishikawa diagram was used to guide physicians to determine the potential risk factors involved in this outbreak. Coherence between the occurrences and each possible cause listed in the diagram was verified, and the total number of eyes at risk was used to calculate the proportion of affected eyes. Multivariate analysis was performed using logistic regression to determine the independent effect of the risk factors, after controlling for confounders and test interactions...
September 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/29160504/nasal-carriage-rate-of-methicillin-resistant-staphylococcus-aureus-among-iranian-healthcare-workers-a-systematic-review-and-meta-analysis
#12
Mohammad Emaneini, Fereshteh Jabalameli, Hosseinali Rahdar, Willem B van Leeuwen, Reza Beigverdi
Globally, methicillin-resistant Staphylococcus aureus (MRSA) remains a major cause of healthcare-associated infections. Healthcare workers (HCWs), patients and the environment may act as reservoirs for the spread of MRSA to patients and other HCWs. Screening and eradication of MRSA colonization is an effective method of reducing the MRSA infection rate. There are limited data on the prevalence of MRSA among Iranian HCWs. We performed a systematic search by using different electronic databases including Medline (via PubMed), Embase, Web of Science, and Iranian Databases (from January 2000 to July 2016)...
September 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29160170/diagnostic-x-ray-exposure-and-thyroid-cancer-risk-systematic-review-and-meta-analysis
#13
Mi Ah Han, Jin Hwa Kim
BACKGROUND: Radiation exposure is a well-known risk factor for thyroid cancer. However, the specific effects of diagnostic radiation exposure on thyroid cancer risk are controversial. The purpose of this study was to perform a systematic review and meta-analysis to assess the effects of diagnostic radiation exposure on thyroid cancer risk. METHODS: The PubMed and EMBASE databases were searched to identify eligible studies. Summary odds ratio (OR) estimates and 95% confidence intervals (CIs) were used to compute the risk of thyroid cancer using fixed- and random-effects models...
November 21, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29160163/cancer-risk-associated-with-nuclear-atypia-in-cytologically-indeterminate-thyroid-nodules-a-systematic-review-and-meta-analysis
#14
Pablo Valderrabano, Laila Khazai, Zachary J Thompson, Susan C Sharpe, Valentina D Tarasova, Kristen J Otto, Julie E Hallanger-Johnson, J Trad Wadsworth, Bruce M Wenig, Christine H Chung, Barbara A Centeno, Bryan McIver
BACKGROUND: Indeterminate categories of thyroid cytopathology (categories B-III and B-IV of the Bethesda system) are integrated by a heterogeneous spectrum of cytological scenarios that are generally clustered for analysis and management recommendations. It has been suggested that aspirates exhibiting nuclear atypia have a higher risk of malignancy. We assess whether cytologically indeterminate thyroid nodules with nuclear atypia have a significantly higher cancer risk than those without nuclear atypia...
November 21, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29160070/cation-hydration-in-supercritical-naoh-and-hcl-aqueous-solutions
#15
Christoph J Sahle, Johannes Niskanen, Christian Schmidt, Johannes Stefanski, Keith Gilmore, Yury Forov, Sandro Jahn, Max Wilke, Christian Sternemann
We present a study of the local atomic environment of the oxygen atoms in aqueous solutions of NaOH and HCl under simultaneous high temperature and high pressure conditions. Experimental non-resonant X-ray Raman scattering core-level spectra at the oxygen K-edge show systematic changes as a function of temperature and pressure. These systematic changes are distinct for the two different solutes and are described well by calculations within the Bethe-Salpeter formalism for snapshots from {\it ab initio} molecular dynamics simulations...
November 21, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29159874/meta-synthesis-on-migraine-management
#16
REVIEW
Mia T Minen, Lita Anglin, Alexandra Boubour, Allison Squires, Linda Herrmann
BACKGROUND: Migraine is one of the top 10 most disabling conditions among adults worldwide. Most migraine research is quantitative and indicates concerns about medication adherence, stigma, and more. Qualitative studies might reveal an improved understanding of migraine patients' perspectives regarding migraine treatment. OBJECTIVE: The aim of this study was to synthesize the qualitative research on migraine patients' perspectives regarding migraine treatment to (a) identify common patterns across various types of migraine treatment studies and (b) inform future research...
November 21, 2017: Headache
https://www.readbyqxmd.com/read/29159863/genome-wide-gene-environment-interaction-in-depression-a-systematic-evaluation-of-candidate-genes-the-childhood-trauma-working-group-of-pgc-mdd
#17
Sandra Van der Auwera, Wouter J Peyrot, Yuri Milaneschi, Johannes Hertel, Bernhard Baune, Gerome Breen, Enda Byrne, Erin C Dunn, Helen Fisher, Georg Homuth, Douglas Levinson, Cathryn Lewis, Natalie Mills, Niamh Mullins, Matthias Nauck, Giorgio Pistis, Martin Preisig, Marcella Rietschel, Stephan Ripke, Patrick Sullivan, Alexander Teumer, Henry Völzke, Dorret I Boomsma, Naomi R Wray, Brenda Penninx, Hans Grabe
Gene by environment (GxE) interaction studies have investigated the influence of a number of candidate genes and variants for major depressive disorder (MDD) on the association between childhood trauma and MDD. Most of these studies are hypothesis driven and investigate only a limited number of SNPs in relevant pathways using differing methodological approaches. Here (1) we identified 27 genes and 268 SNPs previously associated with MDD or with GxE interaction in MDD and (2) analyzed their impact on GxE in MDD using a common approach in 3944 subjects of European ancestry from the Psychiatric Genomics Consortium who had completed the Childhood Trauma Questionnaire...
November 21, 2017: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/29159776/non-pharmacological-interventions-in-patients-with-spinal-cord-compression-a-systematic-review
#18
REVIEW
María Paniagua-Collado, Omar Cauli
Spinal cord compression is a complex and challenging condition that greatly affects the quality of life. Non-pharmacological techniques have only been studied to a very lesser extent; although they are evidence to be beneficial. We performed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) analysis of the scientific literature in several databases (Medline, Cochrane, Scopus, Cuiden, Pubmed, Lilacs and Embase); using the following keywords: spinal cord compression, spine compression, mobilization, positioning, brace and bracing...
November 20, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29159665/functional-rostro-caudal-gradient-in-the-human-posterior-lateral-frontal-cortex
#19
Céline Amiez, Michael Petrides
The present study examined the hypothesis that the posterior motor/premotor region of the lateral frontal cortex is functionally organized along a rostro-caudal axis. During functional magnetic resonance imaging scanning, the subjects performed various tasks assessing basic saccadic eye or hand actions and also tasks requiring the cognitive selection between competing hand or eye movements based on previously learned conditional relations (if A, select movement X, but if B select movement Y). Subject-by-subject analysis demonstrated precise relationships between the foci of functional activity and specific sulci...
November 20, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/29159552/the-effect-of-helicobacter-pylori-on-postoperative-outcomes-in-patients-undergoing-bariatric-surgery-a-systematic-review-and-meta-analysis
#20
REVIEW
Valentin Mocanu, Jerry T Dang, Noah Switzer, Daniel Skubleny, Xinzhe Shi, Chris de Gara, Daniel W Birch, Shahzeer Karmali
Helicobacter pylori (HP) occurs in 50% of people worldwide with higher rates reported in the bariatric population. HP has been associated with adverse outcomes following bariatric surgery; however, its true impact has not yet been defined. We aimed to systematically review the effect of HP on bariatric surgery outcomes. A comprehensive literature review was conducted yielding seven studies with 255,435 patients. Meta-analysis found comparable rates of bleeding, leak, hospital length of stay, and weight loss between HP-positive and HP-negative patients...
November 21, 2017: Obesity Surgery
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