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https://www.readbyqxmd.com/read/29668968/outcomes-of-endoscopic-resections-of-large-laterally-spreading-colorectal-lesions-in-inflammatory-bowel-disease-a-single-united-kingdom-center-experience
#1
Shraddha Gulati, Andrew Emmanuel, Margaret Burt, Patrick Dubois, Bu'Hussain Hayee, Amyn Haji
Background: The SCENIC consensus statement recommends endoscopic resection of all visible dysplasia in inflammatory bowel disease, but patients with large or complex lesions may still be advised to have colectomy. This article presents outcomes for large nonpolypoid resections associated with colitis at our institution. Methods: Data including demographics, clinical history, lesion characteristics, method of resection, and postresection surveillance were collected prospectively in patients with visible lesions within colitic mucosa from January 2011 to November 2016...
April 13, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29668929/chromoendoscopy-for-dysplasia-surveillance-in-inflammatory-bowel-disease
#2
Ann D Flynn, John F Valentine
Long-standing ulcerative colitis (UC) and extensive Crohn's colitis confer increased risk for development of colorectal cancer. Screening and surveillance colonoscopy programs aim to identify, resect, or detect dysplasia or colorectal cancer. Dysplastic lesions can be removed by endoscopic resection and patients with unresectable lesions can be referred for colectomy at an earlier stage, with the goal of reducing overall morbidity and mortality from colorectal cancer. Surveillance colonoscopy for patients with inflammatory bowel disease (IBD) is endorsed by multiple specialty societies...
April 13, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29658652/additional-chromoendoscopy-for-colorectal-lesions-initially-diagnosed-with-low-confidence-by-magnifying-narrow-band-imaging-can-it-improve-diagnostic-accuracy
#3
REVIEW
Takahiro Utsumi, Mineo Iwatate, Hironori Sunakawa, Akira Teramoto, Daizen Hirata, Santa Hattori, Wataru Sano, Noriaki Hasuike, Kazuhito Ichikawa, Takahiro Fujimori, Yasushi Sano
BACKGROUND AND AIM: Magnifying chromoendoscopy has been one of the most reliable diagnostic methods for distinguishing neoplastic from non-neoplastic lesions. The aim of this prospective study was to clarify the clinical usefulness of magnifying chromoendoscopy for colorectal polyps initially diagnosed with low confidence (LC) by magnifying narrow-band imaging (NBI). METHODS: Consecutive adult patients who underwent total colonoscopic examination with magnifying NBI between July and December 2016 at Sano Hospital were prospectively recruited...
April 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29594172/endoscopic-surveillance-in-inflammatory-bowel-disease
#4
REVIEW
Martin Goetz
Introduction: Endoscopy is a key technique for the surveillance of patients with inflammatory bowel diseases (Crohn's disease (CD) and ulcerative colitis). Indication to perform endoscopy for surveillance includes assessment of response to therapy, postoperative surveillance, and surveillance for intraepithelial neoplasia. Methods: In addition to personal experience, a literature search was performed and the guidelines were consulted. Results and Conclusion: Endoscopy is the gold standard in the long-term assessment of mucosal healing and in the short-term control of response to intensified therapy...
February 2018: Visceral Medicine
https://www.readbyqxmd.com/read/29567006/chromoendoscopy-versus-autofluorescence-imaging-for-neoplasia-detection-in-patients-with-longstanding-ulcerative-colitis-find-uc-an-international-multicentre-randomised-controlled-trial
#5
Jasper L A Vleugels, Matt D Rutter, Krish Ragunath, Colin J Rees, Cyriel Y Ponsioen, Conor Lahiff, Shara N Ket, Linda K Wanders, Sunil Samuel, Faheem Butt, Teaco Kuiper, Simon P L Travis, Geert D'Haens, Lai M Wang, Susanne van Eeden, James E East, Evelien Dekker
BACKGROUND: Patients with longstanding ulcerative colitis undergo regular dysplasia surveillance because they have an increased colorectal cancer risk. Autofluorescence imaging and chromoendoscopy improve dysplasia detection. The aim of this study was to determine whether autofluorescence imaging should be further studied as an alternative method for dysplasia surveillance in patients with longstanding ulcerative colitis. METHODS: This prospective, international, randomised controlled trial included patients from an ulcerative colitis-dysplasia surveillance cohort from five centres in the Netherlands and the UK...
March 19, 2018: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29567005/is-autofluorescence-inferior-to-chromoendoscopy-for-dysplasia-detection-in-ulcerative-colitis
#6
Michael F Picco
No abstract text is available yet for this article.
March 19, 2018: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29563760/colonic-lesion-characterization-in-inflammatory-bowel-disease-a-systematic-review-and-meta-analysis
#7
Richard Lord, Nicholas E Burr, Noor Mohammed, Venkataraman Subramanian
AIM: To perform a systematic review and meta-analysis for the diagnostic accuracy of in vivo lesion characterization in colonic inflammatory bowel disease (IBD), using optical imaging techniques, including virtual chromoendoscopy (VCE), dye-based chromoendoscopy (DBC), magnification endoscopy and confocal laser endomicroscopy (CLE). METHODS: We searched Medline, Embase and the Cochrane library. We performed a bivariate meta-analysis to calculate the pooled estimate sensitivities, specificities, positive and negative likelihood ratios (+LHR, -LHR), diagnostic odds ratios (DOR), and area under the SROC curve (AUSROC) for each technology group...
March 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29551245/early-esophageal-squamous-cell-carcinoma-management-through-endoscopic-submucosal-dissection
#8
V Arantes, J Espinoza-Ríos
The incidence of esophageal cancer is steadily increasing worldwide. Outcome is poor, given that the majority of cases are diagnosed at advanced disease stages. However, when detected at early stages, esophageal tumors can be curatively treated through less invasive methods, resulting in a 5-year survival rate above 90%. Therefore, it is essential to identify the high-risk population and recommend those patients undergo screening using high-resolution endoscopy, adding the resources of chromoendoscopy with Lugol solution (or digital chromoendoscopy) and magnification...
March 15, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29548940/the-paddington-international-virtual-chromoendoscopy-score-picasso-in-ulcerative-colitis-exhibits-very-good-inter-rater-agreement-after-computerized-module-training-a-multicenter-study-across-academic-and-community-practice-with-video
#9
Palak J Trivedi, Ralf Kiesslich, James Hodson, Neeraj Bhala, Ralph A Boulton, Rachel Cooney, Xianyong Gui, Tariq Iqbal, Ka-Kit Li, Saqib Mumtaz, Shri Pathmakanthan, Mohammed Nabil Quraishi, Vandana M Sagar, Ashit Shah, Naveen Sharma, Keith Siau, Samuel Smith, Stephen Ward, Monika M Widlak, Raf Bisschops, Subrata Ghosh, Marietta Iacucci
INTRODUCTION: Electronic virtual chromoendoscopy (EVC) can demonstrate ongoing disease activity in ulcerative colitis (UC), even when Mayo subscores suggest healing. However, applicability of EVC technology outside the expert setting has yet to be determined. METHODS: 15 participants across 5 centers reviewed a computerized training module outlining high-definition (HD) and EVC (i-Scan) colonoscopy modes. Interobserver agreement was then tested (Mayo score, UCEIS and the Paddington International virtual ChromoendoScopy ScOre [PICaSSO] for UC), using a colonoscopy video library (n=30 cases reviewed pre- and n=30 post-training)...
March 13, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29534888/prognostication-of-superficial-barrett-s-carcinoma-a-japanese-multicenter-study
#10
Junko Aida, Tatsuro Ishizaki, Tomio Arai, Kaiyo Takubo
Endoscopic resection (ER) has become the standard therapy for superficial Barrett's carcinoma (BC) in Japan and other countries. Patients undergoing ER sometimes require additional treatment because of recurrence of lymph node metastasis (LNM). We attempted to clarify the histopathologic risk factors for LNM, and the difference between these risk factors for Japanese patients and the conventional risk factors documented for Western patients. This multi-center study included 12 leading institutions belonging to the Japan Research Society for Early Esophageal Cancer and Chromoendoscopy, and was based on a questionnaire designed to gather data on the features of superficial BC cases, except for high-grade intraepithelial neoplasia, treated at those institutions...
March 10, 2018: Human Pathology
https://www.readbyqxmd.com/read/29526386/systematic-alphanumeric-coded-endoscopy-versus-chromoendoscopy-for-the-detection-of-precancerous-gastric-lesions-and-early-gastric-cancer-in-subjects-at-average-risk-for-gastric-cancer
#11
A Pérez-Mendoza, Á M Zárate-Guzmán, E S Galvis García, S Sobrino Cossío, J Djamus Birch
INTRODUCTION AND AIMS: Gastric cancer is one of the main causes of cancer worldwide, but there is currently no global screening strategy for the disease. Endoscopy is the screening method of choice in some Asian countries, but no standardized technique has been recognized. Systematic alphanumeric-coded endoscopy can increase gastric lesion detection. The aim of the present article was to compare the usefulness of systematic alphanumeric-coded endoscopy with conventional endoscopy for the detection of premalignant lesions and early gastric cancer in subjects at average risk for gastric cancer...
March 8, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29516293/an-update-on-surveillance-in-ulcerative-colitis
#12
REVIEW
Jimmy K Limdi, Francis A Farraye
PURPOSE OF REVIEW: Patients with long-standing ulcerative colitis have an increased risk for the development of colorectal cancer (CRC). Colitis-related dysplasia appears to confer the greatest risk. Colonoscopic surveillance to detect dysplasia has been advocated by gastrointestinal societies. The aim of surveillance is the reduction of mortality and morbidity of CRC through detection and resection of dysplasia or detecting CRC at an earlier and potentially curable stage. Traditional surveillance has relied on mucosal assessment with targeted biopsy of visible lesions and random biopsy sampling on the premise that dysplasia was not visible at endoscopy...
March 7, 2018: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29504086/objective-assessment-of-the-utility-of-chromoendoscopy-with-a-support-vector-machine
#13
Ryo Ogawa, Jun Nishikawa, Eizaburo Hideura, Atsushi Goto, Yurika Koto, Shunsuke Ito, Madoka Unno, Yuko Yamaoka, Ryo Kawasato, Shinichi Hashimoto, Takeshi Okamoto, Hiroyuki Ogihara, Yoshihiko Hamamoto, Isao Sakaida
PURPOSE: The utility of chromoendoscopy for early gastric cancer (GC) was determined by machine learning using data of color differences. METHODS: Eighteen histopathologically confirmed early GC lesions were examined. We prepared images from white light endoscopy (WL), indigo carmine (Indigo), and acetic acid-indigo carmine chromoendoscopy (AIM). A border between cancerous and non-cancerous areas on endoscopic images was established from post-treatment pathological findings, and 2000 pixels with equivalent luminance values were randomly extracted from each image of cancerous and non-cancerous areas...
March 5, 2018: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/29477434/computer-assisted-gastric-abnormalities-detection-using-hybrid-texture-descriptors-for-chromoendoscopy-images
#14
Hussam Ali, Mussarat Yasmin, Muhammad Sharif, Mubashir Husain Rehmani
BACKGROUND AND OBJECTIVE: The early diagnosis of stomach cancer can be performed by using a proper screening procedure. Chromoendoscopy (CH) is an image-enhanced video endoscopy technique, which is used for inspection of the gastrointestinal-tract by spraying dyes to highlight the gastric mucosal structures. An endoscopy session can end up with generating a large number of video frames. Therefore, inspection of every individual endoscopic-frame is an exhaustive task for the medical experts...
April 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29462738/detecting-dysplasia-using-white-light-endoscopy-or-chromoendoscopy-in-ulcerative-colitis-patients-without-primary-sclerosing-cholangitis-a-systematic-review-and-meta-analysis
#15
REVIEW
Saeed Azizi, Hussein Al-Rubaye, Mohammed Adil Turki, Muhammad R Sameem Siddiqui, Arun P Shanmuganandan, Bushra Ehsanullah, Ranjeet Brar, Al-Mutaz Abulafi
BACKGROUND: Endoscopic examinations are a vital diagnostic tool for dysplasia. Establishing the precision of different modes of examination is essential due to the disparate pick-up rates of dysplasia. OBJECTIVE: The aim of this article was to establish the pick-up rates of dysplastic or cancerous lesions using white light endoscopy (WLE) and random/targeted biopsies, or chromoendoscopy (CE), in patients with ulcerative colitis (UC) without primary sclerosing (PSC) or Crohn's disease (CD)...
February 17, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29462601/novel-developments-in-endoscopic-mucosal-imaging
#16
F van der Sommen, W L Curvers, W B Nagengast
Endoscopic techniques such as High-definition and optical-chromoendoscopy have had enormous impact on endoscopy practice. Since these techniques allow assessment of most subtle morphological mucosal abnormalities, further improvements in endoscopic practice lay in increasing the detection efficacy of endoscopists. Several new developments could assist in this. First, web based training tools could improve the skills of the endoscopist for enhancing the detection and classification of lesions. Secondly, incorporation of computer aided detection will be the next step to raise endoscopic quality of the captured data...
February 17, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29462390/segmental-resection-versus-total-proctocolectomy-for-crohn-s-colitis-what-is-the-best-operation-in-the-setting-of-medically-refractory-disease-or-dysplasia
#17
Amy L Lightner
Crohn's disease (CD) may affect any part of the gastrointestinal tract. When isolated to the colon, and patients become medically refractory, there are several surgical options - segmental resection, subtotal colectomy with ileorectal anastomosis, or a total proctocolectomy and end ileostomy. Unfortunately, surgery does not cure CD, and, regardless of the extent of bowel removed, recurrence may be seen in the small bowel. This may lead to need for further immunosuppression or surgery. Therefore, when appropriate, a segmental colectomy or subtotal colectomy may prevent a permanent ostomy required with a total proctocolectomy...
February 15, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29459808/-submucosal-endoscopic-dissection-in-the-treatment-of-early-esophageal-cancer
#18
Liliana Ughelli, Carolina Miranda, Carlos Galeano, María Del Carmen Blasco, Guliano Boselli, Antonio Cubilla, Paulo Sakai, Carmelo Blasco
We report the case of a male patient, 80 years old, with a history of dyspepsia and no family history of neoplasias. In the upper digestive endoscopy in the distal esophagus, a flat depressed lesion with the appearance of early carcinoma, type IIC of Paris classification, was diagnosed by biopsy as a squamous carcinoma in situ, infiltrating, moderately differentiated non-keratinizing grade II carcinoma. He underwent submucosal endoscopic dissection without complications. Histopathology concluded: carcinoma of squamous cells, predominantly in situ of distal esophagus, measuring 0...
October 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/29445907/management-of-serrated-polyps-of-the-colon
#19
REVIEW
Claire Fan, Adam Younis, Christine E Bookhout, Seth D Crockett
PURPOSE OF REVIEW: The purpose of this review is to summarize the management of serrated colorectal polyps (SPs), with a particular focus on the most common premalignant SP, sessile serrated adenoma or polyp (SSA/P). These lesions present a challenge for endoscopists with respect to detection and resection, and are also susceptible to pathologic misdiagnosis. RECENT FINDINGS: Patients with SSA/Ps are at an increased risk of future colorectal neoplasia, including advanced polyps and cancer...
March 2018: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/29439278/delineation-of-the-extent-of-early-gastric-cancer-by-magnifying-narrow-band-imaging-and-chromoendoscopy-a-multicenter-randomized-controlled-trial
#20
Takashi Nagahama, Kenshi Yao, Noriya Uedo, Hisashi Doyama, Tetsuya Ueo, Kunihisa Uchita, Hideki Ishikawa, Takashi Kanesaka, Yasuhito Takeda, Kurato Wada, Kentaro Imamura, Hisatomi Arima, Toshio Shimokawa
BACKGROUND: Accurate delineation of tumor margins is necessary for curative resection of early gastric cancer (EGC). The objective of this multicenter, randomized, controlled study was to compare the accuracy with which magnifying narrow-band imaging (M-NBI) and indigo carmine chromoendoscopy delineate EGC margins. METHODS: Patients with EGC ≥ 10 mm undergoing endoscopic or surgical resection were enrolled. The oral-side margins of the lesions were first evaluated with conventional white-light endoscopy in both groups and then delineated by either chromoendoscopy or M-NBI...
February 13, 2018: Endoscopy
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