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https://www.readbyqxmd.com/read/27904863/recent-updates-in-the-endoscopic-diagnosis-of-barrett-s-oesophagus
#1
REVIEW
Neel Sharma, Khek Yu Ho
BACKGROUND: Barrett's oesophagus (BO) is a premalignant condition associated with the development of oesophageal adenocarcinoma (OAC). Despite the low risk of progression per annum, OAC is associated with significant morbidity and mortality, with an estimated 5-year survival of 10%. Furthermore, the incidence of OAC continues to rise globally. Therefore, it is imperative to detect the premalignant phase of BO and follow up such patients accordingly. SUMMARY: The mainstay diagnosis of BO is endoscopy and biopsy sampling...
October 2016: Gastrointestinal Tumors
https://www.readbyqxmd.com/read/27904859/endoscopic-approach-for-superficial-colorectal-neoplasms
#2
REVIEW
Jun-Feng Xu, Lang Yang, Peng Jin, Jian-Qiu Sheng
BACKGROUND: Colorectal cancer (CRC) is the third most commonly diagnosed cancer in males and the second in females, with an estimated 1.4 million cases and 693,900 deaths in 2012. Colonoscopy is the cornerstone for the detection and prevention of CRC. In addition, endoscopic treatment for CRC at an early stage can effectively improve patients' quality of life and cure rate. SUMMARY: This review focuses on endoscopic approaches, including white light endoscopy, chromoendoscopy, magnifying endoscopy and therapeutic endoscopy, for the evaluation and treatment of superficial colorectal neoplasms...
October 2016: Gastrointestinal Tumors
https://www.readbyqxmd.com/read/27890853/chromoendoscopy-for-surveillance-in-ulcerative-colitis-and-crohn-s-disease-a-systematic-review-of-randomized-trials
#3
REVIEW
Andrea Iannone, Marinella Ruospo, Germaine Wong, Mariabeatrice Principi, Michele Barone, Giovanni Fm Strippoli, Alfredo Di Leo
BACKGROUND & AIMS: Key international guideline agencies recommend dysplasia surveillance in inflammatory bowel diseases with chromoendoscopy. We performed a systematic review of randomized trials comparing chromoendoscopy versus other endoscopic techniques for dysplasia surveillance in inflammatory bowel diseases. METHODS: We searched MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials for relevant studies published through September 2016. We estimated risk ratios (RR) for dichotomous outcomes (all-cause/colorectal cancer-related mortality, time to interval cancer, patients with dysplasia, total/subtypes of dysplastic lesions, dysplasia detected by targeted biopsies, adverse events), mean differences (MD) for continuous outcomes (procedural time, costs, total/targeted biopsies) and their 95% confidence intervals (CI) using a random-effects model...
November 24, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27884517/endoscopic-morphological-features-of-ulcerative-colitis-associated-dysplasia-classified-according-to-the-scenic-consensus-statement
#4
Shinya Sugimoto, Makoto Naganuma, Yasushi Iwao, Katsuyoshi Matsuoka, Masayuki Shimoda, Shuji Mikami, Shinta Mizuno, Yoshihiro Nakazato, Kosaku Nanki, Nagamu Inoue, Haruhiko Ogata, Takanori Kanai
BACKGROUND AND AIMS: Recent advances in endoscopic equipment and diagnostic techniques have made possible the detection of early dysplasia in the inflamed mucosa of ulcerative colitis (UC). The SCENIC consensus statement recommends the use of unified terminology for the morphology of dysplasia. In this study, we investigated the endoscopic features of high-grade dysplasia (HGD) in a clinical setting. METHODS: We retrospectively identified 62 patients with UC who were diagnosed with colitis-associated cancer or HGD between 1997 and 2015...
November 21, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27878770/a-low-cost-method-for-chromoendoscopy-for-surveillance-in-ulcerative-colitis
#5
Sawan Bopanna, Saurabh Kedia, Vineet Ahuja
The risk of colorectal cancer in Indian patients with long-standing ulcerative colitis is high and similar to that in the West. Surveillance for dysplasia in these patients is therefore important. Recent studies and guidelines suggest an increasing role for chromoendoscopy-guided biopsy in surveillance for dysplasia. We report our experience with the technique of chromoendoscopy and an economical method of performing it. Reconstituting indigo carmine from a powder form rather than the dyes available commercially is a better economical alternative and should help make chromoendoscopy the standard of care for dysplasia surveillance across the country...
November 23, 2016: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/27862291/probe-based-confocal-laser-endomicroscopy-in-the-margin-delineation-of-early-gastric-cancer-for-endoscopic-submucosal-dissection
#6
Jun Chul Park, Yehyun Park, Hyun Ki Kim, Jeong-Hyeon Jo, Chan Hyuk Park, Eun Hye Kim, Da Hyun Jung, Hyunsoo Chung, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee
BACKGROUND AND AIM: We evaluated pCLE in the margin delineation of early gastric cancer (EGC) for endoscopic submucosal dissection (ESD) in comparison with white-light imaging with chromoendoscopy (CE). METHODS: We conducted a prospective, randomized controlled study from November 2013 to October 2014 in a tertiary referral hospital. A total of 101 patients scheduled for ESD due to differentiated EGC were randomized into pCLE and CE groups (pCLE 51, CE 50). Markings were made by electrocautery at the proximal and distal tumor margins, as determined by either pCLE or CE...
November 9, 2016: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27848960/endoscopy-chromoendoscopy-in-ibd-indispensable-in-real-life-screening
#7
Raja Atreya, Markus F Neurath
No abstract text is available yet for this article.
November 16, 2016: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27816496/advanced-endoscopy-imaging-in-inflammatory-bowel-diseases
#8
REVIEW
Ralf Kiesslich, Markus F Neurath
BACKGROUND AND AIMS: Rapid assessment of mucosal inflammation is of crucial importance for the initial diagnosis and the assessment of mucosal healing in inflammatory bowel diseases (IBD). Moreover, the identification of intraepithelial neoplasias in IBD is of key relevance for clinical management. Here, we systematically analyzed the utility of advanced endoscopic imaging techniques for optimized diagnosis in IBD. METHODS: PubMed/Medline, Web of Knowledge and Cochrane library were searched twice for diagnostic studies on advanced endoscopic imaging in IBD...
November 2, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27807370/role-of-endoscopy-in-early-oesophageal-cancer
#9
REVIEW
Jayan Mannath, Krish Ragunath
Incidence of oesophageal adenocarcinoma has increased exponentially in the West over the past few decades. Following detection of advanced cancers, 5-year survival rates remain bleak, making identification of early neoplasia, which has a better outcome, important. Detection of subtle oesophageal lesions during endoscopy can be challenging, and advanced imaging techniques might improve their detection. High-definition endoscopy has become a standard in most endoscopy centres, and this technology probably provides better delineation of mucosal features than standard-definition endoscopy...
November 3, 2016: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27806411/anal-chromoendoscopy-using-gastroenterological-video-endoscopes-a-new-method-to-perform-high-resolution-anoscopy-for-diagnosing-intraepithelial-neoplasia-and-anal-carcinoma-in-hiv-infected-patients
#10
M Oette, U Wieland, M Schünemann, J Haes, S Reuter, B Jensen, A Sagir, H Pfister, D Häussinger
Introduction: Anal carcinoma represents an increasing problem in HIV-infected patients. Anal intraepithelial neoplasia (AIN), the precursor lesion, is currently diagnosed by high-resolution anoscopy (HRA) using optical magnification derived from gynecological colposcopy. This prospective study evaluates anal chromoendoscopy (ACE) using standard gastroenterological video-endoscopes in diagnosing AIN. Methods: After clinical examination, proctoscopy and surface staining with acetic acid followed by Lugol's solution, ACE was performed with a mucosectomy cap on the tip of the endoscope...
November 2, 2016: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/27752392/usefulness-of-endoscopic-imaging-to-visualize-regional-alterations-in-acid-secretion-of-noncancerous-gastric-mucosa-after-helicobacter-pylori-eradication
#11
Kaname Uno, Katsunori Iijima, Yasuhiko Abe, Tomoyuki Koike, Yasushi Takahashi, Nobuyuki Ara, Tooru Shimosegawa
PURPOSE: Endoscopic diagnosis of gastric cancer (GC) that emerges after eradication of Helicobacter pylori may be affected by unique morphological changes. Using comprehensive endoscopic imaging, which can reveal biological alterations in gastric mucosa after eradication, previous studies demonstrated that Congo red chromoendoscopy (CRE) might clearly show an acid non-secretory area (ANA) with malignant potential, while autofluorescence imaging (AFI) without drug injection or dyeing may achieve early detection or prediction of GC...
September 2016: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/27741536/reassessment-colonoscopy-to-diagnose-serrated-polyposis-syndrome-in-a-colorectal-cancer-screening-population
#12
Liseth Rivero-Sanchez, Maria Lopez-Ceron, Sabela Carballal, Leticia Moreira, Xavier Bessa, Anna Serradesanferm, Angels Pozo, Josep Maria Augé, Teresa Ocaña, Ariadna Sánchez, María Liz Leoz, Míriam Cuatrecasas, Jaume Grau, Josep Llach, Antoni Castells, Francesc Balaguer, Maria Pellisé
Background and study aims: Serrated polyposis syndrome (SPS) is a high risk condition for colorectal cancer (CRC). Surveillance strategies for patients with serrated lesions remain controversial. We aimed to evaluate a diagnostic strategy to detect SPS consistently during reassessment colonoscopy in patients with proximal serrated lesions. Methods: This was a retrospective study of all individuals from a fecal immunochemical test (FIT)-based CRC screening program (2010 - 2013) with one or more serrated lesions of ≥ 5 mm proximal to the sigmoid colon on baseline colonoscopy...
October 14, 2016: Endoscopy
https://www.readbyqxmd.com/read/27693809/ultrastructural-investigation-of-pelvic-peritoneum-in-patients-with-chronic-pelvic-pain-and-subtle-endometriosis-in-association-with-chromoendoscopy
#13
Abolfazl Mehdizadehkashi, Kobra Tahermanesh, Abbas Fazel Anvari-Yazdi, Shahla Chaichian, Negar Azarpira, Malihe Nobakht, Seyedeh Mehr Abed, Neda Hashemi
STUDY OBJECTIVE: In general, in the context of chronic pelvic pain (CPP) and endometriosis, there is no established relationship between the severity of pain and stage of endometriosis. The aim of this study was to evaluate the pelvic peritoneum under chromoendoscopy by Scanning Electron Microscopy (SEM) as well as light microscopy with H&E staining and immunohistochemical assay in patients of CPP associated with subtle endometriosis. DESIGN: Case series study. DESIGN: classification: Canadian Task Force classification II...
September 29, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27689191/the-efficacy-of-virtual-chromoendoscopy-in-the-diagnosis-of-portal-hypertensive-gastropathy
#14
Anda Carmen Achim, Stefan Cristian Vesa, Eugen Dumitru
BACKGROUND: Diagnosis of portal hypertensive gastropathy (PHG) is based on endoscopic criteria. I-scan technology, a new technique of virtual chromoendoscopy, increases the diagnostic accuracy for lesions in the gastrointestinal tract. AIM: To establish the role of i-scan endoscopy in the diagnosis of PHG. METHOD: In this prospective study, endoscopic examination was conducted first by using white light and after that i-scan 1 and i-scan 2 technology in a group of 50 consecutive cirrhotic patients...
September 2016: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/27644737/narrow-band-imaging-magnifying-chromoendoscopy-and-gross-morphological-features-for-the-optical-diagnosis-of-t1-colorectal-cancer-and-deep-submucosal-invasion-a-systematic-review-and-meta-analysis
#15
Y Backes, A Moss, J B Reitsma, P D Siersema, L M G Moons
OBJECTIVES: Optical diagnosis of T1 colorectal cancer (CRC) and T1 CRC with deep submucosal invasion is important in guiding the treatment strategy. The use of advanced imaging is not standard clinical practice in Western countries. A systematic review and meta-analysis were conducted comparing the accuracy of narrow band imaging (NBI), magnifying chromoendoscopy (MCE), and gross morphological features (GMF) seen with conventional view for the optical diagnosis of T1 CRC and deep submucosal invasion...
September 20, 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27613257/low-rate-of-dysplasia-detection-in-mucosa-surrounding-dysplastic-lesions-in-patients-undergoing-surveillance-for-inflammatory-bowel-diseases
#16
Joren R Ten Hove, Erik Mooiweer, Evelien Dekker, Andrea E van der Meulen-de Jong, G Johan A Offerhaus, Cyriel Y Ponsioen, Peter D Siersema, Bas Oldenburg
BACKGROUND & AIMS: When dysplastic lesions are encountered during surveillance colonoscopy of patients with inflammatory bowel disease (IBD), guidelines recommend collection of additional biopsies from the surrounding mucosa to ensure the lesion has been adequately circumscribed. We aimed to determine the rate of dysplasia in mucosa biopsies collected from tissues surrounding dysplastic lesions during IBD surveillance. METHODS: In a retrospective study, we collected endoscopy and pathology reports from 1065 patients undergoing colonoscopic surveillance for IBD from 2000 through 2015 at 3 centers in the Netherlands...
September 6, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27612488/real-life-chromoendoscopy-for-neoplasia-detection-and-characterisation-in-long-standing-ibd
#17
Sabela Carballal, Sandra Maisterra, Antonio López-Serrano, Antonio Z Gimeno-García, María Isabel Vera, José Carlos Marín-Garbriel, José Díaz-Tasende, Lucía Márquez, Marco Antonio Álvarez, Luis Hernández, Luisa De Castro, Jordi Gordillo, Ignasi Puig, Pablo Vega, Marco Bustamante-Balén, Juan Acevedo, Beatriz Peñas, María López-Cerón, Elena Ricart, Miriam Cuatrecasas, Mireya Jimeno, María Pellisé
OBJECTIVE: Outside clinical trials, the effectiveness of chromoendoscopy (CE) for long-standing IBD surveillance is controversial. We aimed to assess the effectiveness of CE for neoplasia detection and characterisation, in real-life. DESIGN: From June 2012 to 2014, patients with IBD were prospectively included in a multicentre cohort study. Each colonic segment was evaluated with white light followed by 0.4% indigo carmine CE. Specific lesions' features were recorded...
September 9, 2016: Gut
https://www.readbyqxmd.com/read/27577845/diagnosis-of-helicobacter-pylori-related-chronic-gastritis-gastric-adenoma-and-early-gastric-cancer-by-magnifying-endoscopy
#18
Nei Soma
Evaluating the prevalence of gastritis by endoscopy is useful for estimating the risk of gastric cancer. Moreover, understanding the endoscopic appearances of gastritis is important for diagnosing gastric cancer due to the superficial mucosal lesions that mimic gastritis (gastritis-like lesions) are very difficult to detect even with optimum preparation and the best technique, and in such cases the tissue biopsy is often not very accurate for the diagnosis of gastric epithelial neoplasia. Magnifying endoscopy is a highly accurate technique for the detection of EGC (early gastric cancer)...
August 31, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27573777/endoluminal-diagnosis-of-early-gastric-cancer-and-its-precursors-bridging-the-gap-between-endoscopy-and-pathology
#19
Noriya Uedo, Kenshi Yao
Although dye-based and image-enhanced endoscopic techniques have revolutionized endoscopic diagnosis, conventional white light endoscopy still plays an important role in the diagnosis of early gastric cancer (EGC) during routine endoscopy. Chromoendoscopy reveals morphological characteristics of the mucosal lesions by enhancing mucosal contrast, while narrow-band imaging (NBI) facilitates detailed evaluation of the vascular architecture and surface features. Positive diagnostic findings of EGC on white light imaging and indigo carmine chromoendoscopy are a sharply demarcated lesion and irregularity in surface morphology or color...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27573768/diagnosis-by-endoscopy-and-advanced-imaging-of-barrett-s-neoplasia
#20
Anne-Fré Swager, Wouter L Curvers, Jacques J Bergman
Evaluation of patients with Barrett's esophagus (BE) using dye-based chromoendoscopy, optical chromoendoscopy, autofluorescence imaging, or confocal laser endomicroscopy does not significantly increase the number of patients with a diagnosis of early neoplasia compared with high-definition white light endoscopy (HD-WLE) with random biopsy analysis. These newer imaging techniques are not more effective in standard surveillance of patients with BE because the prevalence of early neoplasia is low and HD-WLE with random biopsy analysis detects most cases of neoplasia...
2016: Advances in Experimental Medicine and Biology
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