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https://www.readbyqxmd.com/read/28213106/oral-treatment-with-essential-oil-of-hyptis-spicigera-lam-lamiaceae-reduces-acute-pain-and-inflammation-in-mice-potential-interactions-with-transient-receptor-potential-trp-ion-channels
#1
Róli Rodrigues Simões, Igor Dos Santos Coelho, Stella Célio Junqueira, Glauce Regina Pigatto, Marcos José Salvador, Adair Roberto Soares Santos, Felipe Meira de Faria
ETHNOPHARMACOLOGICAL RELEVANCE: The genus Hyptis comprehends almost 400 species widespread in tropical and temperate regions of America. The use of Hyptis spicigera Lam. (Lamiaceae) is reported in traditional medicine due to its gastroprotective, anti-inflammatory and analgesic properties. AIM OF THE STUDY: The rationale of this study was to investigate the potential use of the essential oil of H. spicigera (EOHs) as analgesic. MATERIAL AND METHODS: The antinociceptive effect of EOHs was verified analyzing acute nocifensive behavior of mice induced by chemical noxious stimuli [i...
February 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28212790/the-echinococcoses-diagnosis-clinical-management-and-burden-of-disease
#2
P Kern, A Menezes da Silva, O Akhan, B Müllhaupt, K A Vizcaychipi, C Budke, D A Vuitton
The echinococcoses are chronic, parasitic diseases that are acquired after ingestion of infective taeniid tapeworm eggs from certain species of the genus Echinococcus. Cystic echinococcosis (CE) occurs worldwide, whereas, alveolar echinococcosis (AE) is restricted to the northern hemisphere, and neotropical echinococcosis (NE) has only been identified in Central and South America. Clinical manifestations and disease courses vary profoundly for the different species of Echinococcus. CE presents as small to large cysts, and has commonly been referred to as 'hydatid disease', or 'hydatidosis'...
2017: Advances in Parasitology
https://www.readbyqxmd.com/read/28211614/opportunities-for-improving-triple-negative-breast-cancer-outcomes-results-of-a-population-based-study
#3
Elisabetta Rapiti, Kim Pinaud, Pierre O Chappuis, Valeria Viassolo, Aurélie Ayme, Isabelle Neyroud-Caspar, Massimo Usel, Christine Bouchardy
Triple-negative breast cancer (TNBC) is associated with a poor prognosis. Surgery, radiotherapy, chemotherapy, and referral for genetic counseling are the standard of care. We assessed TNBC prevalence, management, and outcome using data from the population-based Geneva cancer registry. 2591 women had a first invasive stage I-III breast cancer diagnosed between 2003 and 2011. We compared TNBC to other breast cancers (OBC) by χ(2) -test and logistic regression. Kaplan-Meier survival curves, up to 31-12-2014, were compared using log-rank test...
February 17, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28199442/phylogeographic-history-of-south-american-populations-of-the-silky-anteater-cyclopes-didactylus-pilosa-cyclopedidae
#4
Raphael Teodoro Franciscani Coimbra, Flávia Regina Miranda, Camila Clozato Lara, Marco Antônio Alves Schetino, Fabrício Rodrigues Dos Santos
Cyclopes didactylus, commonly called silky anteater, is the smallest and least studied of the anteaters. It is an arboreal species occurring in rainforests, ranging from southern Mexico to Central and South America, with an apparently disjoint distribution between Amazon and Atlantic rainforests in Brazil. Although seven subspecies are recognized, little is known about its geographical variation. Thus, to evaluate the population dynamics and evolutionary history of the South American silky anteater, we analyzed 1542 bp sequences of the mitochondrial control region (CR), COI and Cyt-b genes of 32 individuals...
February 13, 2017: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/28198632/engineering-oral-and-parenteral-amorphous-amphotericin-b-formulations-against-experimental-trypanosoma-cruzi-infections
#5
Miriam Rolón, Dolores R Serrano, Aikaterini Lalatsa, Esther de Pablo, Juan Jose Torrado, Maria Paloma Ballesteros, Anne Marie Healy, Celeste Vega, Cathia Coronel, Francisco Bolas-Fernández, Maria Auxiliadora Dea-Ayuela
Chagas disease (CD) is a parasitic zoonosis endemic in most mainland countries of Central and South America affecting nearly 10 million people, with 100 million people at high risk of contracting the disease. Treatment is only effective if received at the early stages of the disease. Only two drugs (benznidazole and nifurtimox) have so far been marketed and both share various limitations such as variable efficacy, many side effects and long duration of treatment, thus reducing compliance. The in vitro and in vivo efficacy of poly-aggregated amphotericin B (AmB), encapsulated poly-aggregated AmB in albumin microspheres (AmB-AME) and dimeric AmB - sodium deoxycholate micelles (AmB-NaDC) was evaluated...
February 15, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28198446/a-mutation-identified-in-neonatal-microcephaly-destabilizes-zika-virus-ns1-assembly-in-vitro
#6
Deping Wang, Cheng Chen, Shengnan Liu, Han Zhou, Kailin Yang, Qi Zhao, Xiaoyun Ji, Chen Chen, Wei Xie, Zefang Wang, Li-Zhi Mi, Haitao Yang
An unprecedented epidemic of Zika virus (ZIKV) infection had spread to South and Central America. ZIKV infection was recently confirmed by CDC (the Centers for Disease Control and Prevention) to cause neonatal microcephaly, which posed a significant public health emergency of international concern. No specific vaccines or drugs are currently available to fight ZIKV infection. ZIKV nonstructural protein 1 (NS1) plays an essential role in viral replication and immune evasion. We determined the crystal structure of ZIKV NS1172-352, which forms a head-to-head, symmetric dimer with a unique 14-stranded β-ladder conserved among flaviviruses...
February 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28192040/prevalence-of-columbid-herpesvirus-infection-in-feral-pigeons-columba-livia-from-new-south-wales-and-victoria-australia-with-spillover-into-a-wild-powerful-owl-ninox-struena
#7
David N Phalen, Carolina Alvarado, Victoria Grillo, Phillipa Mason, Elizabeth Dobson, Peter Holz
Columbid herpesvirus-1 (CoHV-1) is widespread in feral pigeons ( Columba livia ) in North America and Europe. We used a PCR assay to detect CoHV-1 DNA in oral and cloacal tissues and oral swabs from naturally infected pigeons. Fifty-three feral pigeons from five flocks in Australia (n=3 from south-central Victoria and n=2 from Sydney) were examined for CoHV-1 DNA. We detected CoHV-1 DNA in oral mucosa and cloacal mucosa, with higher concentrations in the oral mucosa. The sensitivity of testing oral swabs was the same as testing the tissue, indicating that testing of oral swabs from live birds is an effective means of screening flocks for CoHV-1 infection...
February 13, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28187655/-i-digitonthophagus-i-i-gazella-i-auctorum-an-unfortunate-case-of-mistaken-identity-for-a-widely-introduced-species-coleoptera-scarabaeidae-scarabaeinae-onthophagini
#8
François Génier, Adrian L V Davis
At risk of committing entomological heresy, we question the identity of a dung-burying beetle species that originates from Africa and has been introduced first into Hawaii and subsequently to Australasia, North America, and South America (Fincher 1986; Edwards 2007; Noriega et al. 2010) for pasture improvement and biological control of dung-breeding flies (Waterhouse 1974; Bornemissza 1979).  Under the name Onthophagus gazella (Fabricius 1787), it was the first species selected for introduction into Australia by the CSIRO Dung Beetle Project (Bornemissza 1976; Edwards 2007)...
January 19, 2017: Zootaxa
https://www.readbyqxmd.com/read/28187649/variation-of-plumage-patterns-geographic-distribution-and-taxonomy-of-the-unicolored-blackbird-aves-icteridae
#9
Leonardo Esteves Lopes
The Unicolored Blackbird Agelasticus cyanopus (Vieillot, 1819) is a marsh bird with four allopatric subspecies restricted to lowlands in South America east of the Andes. I conducted a taxonomic revision of the species based on analysis of external morphological characters of 288 study skins, including all types available. My revision shows that: 1) Leistes unicolor Swainson, 1838, is a senior synonym of A. c. xenicus (Parkes, 1966) and, therefore, the correct name of the taxon should be A. c. unicolor (Swainson, 1838); 2) the range of A...
January 19, 2017: Zootaxa
https://www.readbyqxmd.com/read/28187628/an-analytical-review-of-halffter-s-mexican-transition-zone-and-its-relevance-for-evolutionary-biogeography-ecology-and-biogeographical-regionalization
#10
Gonzalo Halffter, Juan J Morrone
The Mexican transition zone (MTZ) is the complex area where the Neotropical and Nearctic biotas overlap, including south-western United States, Mexico and a large part of Central America extending to the Nicaraguan lowlands. In a strict sense, it corresponds to the mountain highlands of Mexico, Guatemala, Honduras, El Salvador and Nicaragua. We review Halffter's theory explaining the biotic evolution of the MTZ, including the description and discussion of the distributional patterns and cenocrons recognized within it...
January 25, 2017: Zootaxa
https://www.readbyqxmd.com/read/28183129/the-type-localities-of-i-anolis-i-i-aequatorialis-i-werner-1894-sauria-iguania-dactyloidae-and-i-pristimantis-i-i-appendiculatus-i-werner-1894-amphibia-anura-craugastoridae
#11
Diego F Cisneros-Heredia
The eminent Austrian zoologist Franz Werner described several new species of amphibians and reptiles from America, including Anolis aequatorialis Werner, 1894 and Hylodes appendiculatus Werner, 1894. Both species were described based on single specimens, with no more specific type localities than "Ecuador" (Werner 1894a,b). After its description, A. aequatorialis remained unreported until Peters (1967) and Fitch et al. (1976) published information on its distribution and natural history. Anolis aequatorialis is currently known to inhabit low montane and cloud forest on the western slopes of the Andes from extreme southern Colombia to central Ecuador, between 1300 and 2300 m elevation (Ayala-Varela & Velasco 2010; Ayala-Varela et al...
January 4, 2017: Zootaxa
https://www.readbyqxmd.com/read/28181379/inhibitory-effects-of-leucaena-leucocephala-on-the-metastasis-and-invasion-of-human-oral-cancer-cells
#12
Hsiao-Hang Chung, Mu-Kuan Chen, Yu-Chao Chang, Shun-Fa Yang, Chia-Chieh Lin, Chiao-Wen Lin
Oral cancer is one of the most common cancers worldwide, and metastasis is recognized as a major factor causing its low survival rate. The inhibition of metastasis progress and the improvement of the survival rate for oral cancer are critical research objectives. Leucaena leucocephala from the mimosa branch Leucaena genus is native to Central and South America and has been used as a traditional remedy for treating various disorders. Previous studies have demonstrated antioxidant, anti-inflammatory as well as anticancer properties of L...
February 9, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/28179114/medicinal-plants-used-to-treat-snakebite-in-central-america-review-and-assessment-of-scientific-evidence
#13
REVIEW
Peter Giovannini, Melanie-Jayne R Howes
ETHNOPHARMACOLOGICAL RELEVANCE: Every year between 1.2 and 5.5 million people worldwide are victims of snakebites, with about 400,000 left permanently injured. In Central America an estimated 5,500 snakebite cases are reported by health centres, but this is likely to be an underestimate due to unreported cases in rural regions. The aim of this study is to review the medicinal plants used traditionally to treat snakebites in seven Central American countries: Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama...
February 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28178991/an-ethnographic-study-of-salt-use-and-humoral-concepts-in-a-latino-farm-worker-community-in-california-s-central-valley
#14
Judith C Barker, Claudia Guerra, M Judy Gonzalez-Vargas, Kristin S Hoeft
BACKGROUND: This article reports on the use of domestic or table salt for its perceived health effects and healing properties in a Latino farmworker community. It explores how contemporary salt usage beliefs can be seen to have roots in long-standing humoral theories of medicine and health. METHODS: This qualitative investigation comprised 30 in-depth individual interviews and five focus groups conducted in Spanish with Mexican and Central American immigrants in one small city in California's Central Valley (N = 61 total participants)...
February 8, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28178905/adult-t-cell-leukemia-lymphoma-in-south-and-central-america-and-the-caribbean-systematic-search-and-review
#15
Pedro D Oliveira, Rebeca F de Carvalho, Achiléa L Bittencourt
Adult T-cell leukemia/lymphoma (ATL) is caused by the human T-cell lymphotropic virus type 1 (HTLV-1) which is endemic in countries of Caribbean and Central and South America. We performed a systematic search and review to identify publications on ATL in these countries to verify if this disease was getting recognition in these regions as well as the characteristics of the observed cases. The median age of 49.4 years was lower than that referred to in Japan. According to our findings in most Brazilian states and in some other countries, ATL is not being recognized and should be strongly considered in the differential diagnosis of T-cell leukemias/lymphomas...
March 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28178770/interventions-to-improve-antibiotic-prescribing-practices-for-hospital-inpatients
#16
REVIEW
Peter Davey, Charis A Marwick, Claire L Scott, Esmita Charani, Kirsty McNeil, Erwin Brown, Ian M Gould, Craig R Ramsay, Susan Michie
BACKGROUND: Antibiotic resistance is a major public health problem. Infections caused by multidrug-resistant bacteria are associated with prolonged hospital stay and death compared with infections caused by susceptible bacteria. Appropriate antibiotic use in hospitals should ensure effective treatment of patients with infection and reduce unnecessary prescriptions. We updated this systematic review to evaluate the impact of interventions to improve antibiotic prescribing to hospital inpatients...
February 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28177969/zika-virus-practical-information-for-the-plastic-and-reconstructive-surgeon
#17
Nicholas A Calotta, Justin M Sacks, Anand R Kumar
The ongoing Zika virus outbreak in South, Central, and, most recently, North America has become a global health care emergency. Originally thought to be a benign, self-limiting viral syndrome, the newest epidemic has provided convincing evidence that maternal Zika virus infection can lead to neonatal malformations, the so-called congenital Zika syndrome. The alarming number of microcephalic neonates being born during the current outbreak is most notable, though several other anomalies, such as arthrogryposis, redundant scalp tissue, and cranial collapse, have been reported...
February 8, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28177197/army-ant-invasions-reveal-phylogeographic-processes-across-the-isthmus-of-panama
#18
Seán G Brady
Female army ants cannot fly, making them very poor dispersers across water barriers. This dependence on terrestrial corridors motivated the investigation by Winston et al. (), published in this issue of Molecular Ecology, into the role of Panamanian isthmus formation in the diversification of Eciton army ants. Complete closure of this isthmus occurred around three million years ago (3 Ma), but it has also been hypothesized that earlier, temporary land connections facilitated additional colonization events between South and Central America over the past 13 million years or more...
February 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28176186/ethnic-inequalities-in-acute-myocardial-infarction-hospitalization-rates-among-young-and-middle-aged-adults-in-northern-italy-high-risk-for-south-asians
#19
Ugo Fedeli, Laura Cestari, Eliana Ferroni, Francesco Avossa, Mario Saugo, Pietro Amedeo Modesti
The knowledge of ethnic-specific health needs is now essential to design effective health services and population-based prevention strategies. However, data on migrant populations living in Southern Europe are limited. The study is designed to investigate ethnic inequalities in hospitalization for acute myocardial infarction (AMI) in the Veneto region (Italy). Hospital admissions for AMI in Veneto for the whole resident population aged 20-59 years during 2008-2013 were studied. Age and gender-specific AMI hospitalization rates for immigrant groups (classified by country of origin according to the United Nations geoscheme) and Italians were calculated...
February 7, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28169346/multiple-tropical-andean-glaciations-during-a-period-of-late-pliocene-warmth
#20
Nicholas J Roberts, René W Barendregt, John J Clague
The extent and behaviour of glaciers during the mid-Piacenzian warm period illustrate the sensitivity of the cryosphere to atmospheric CO2 concentrations above pre-industrial levels. Knowledge of glaciation during this period is restricted to globally or regionally averaged records from marine sediments and to sparse terrestrial glacial deposits in mid-to-high latitudes. Here we expand the Pliocene glacial record to the tropics by reporting recurrent large-scale glaciation in the Bolivian Andes based on stratigraphic and paleomagnetic analysis of a 95-m sequence of glacial sediments underlying the 2...
February 7, 2017: Scientific Reports
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