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https://www.readbyqxmd.com/read/28640884/human-lagochilascariasis-a-rare-helminthic-disease
#1
REVIEW
Dulcinea Maria Barbosa Campos, Alverne Passos Barbosa, Jayrson Araújo de Oliveira, Giovana Galvão Tavares, Pedro Vitor Lemos Cravo, Alejandro Luquetti Ostermayer
Lagochilascariasis is a parasitic disease caused by a helminth of the order Ascaroidea, genus Lagochilascaris that comprises 6 species, among which only Lagochilascaris minor Leiper, 1909, is implicated in the human form of the disease. It is remarkable that the majority of cases of human lagochilascariasis in the Americas have been reported in Brazil. The natural definitive hosts of this parasite seem to be wild felines and canines. Lagochilascariasis is mostly a chronic human disease that can persist for several years, in which the parasite burrows into the subcutaneous tissues of the neck, paranasal sinuses, and mastoid...
June 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28637192/an-explorative-study-examining-augmentative-and-alternative-communication-training-in-the-field-of-music-therapy
#2
Anita L Gadberry, Alison Sweeney
Background: Music therapists work with many people who require Augmentative and Alternative Communication (AAC). As communication goals are central to music therapy practice, many music therapists would benefit from training in AAC. Objective: The purpose of this survey study was to determine the state of AAC education for music therapists at the university level, how AAC is being used in music therapy sessions, and how practicing music therapists are trained in AAC...
June 20, 2017: Journal of Music Therapy
https://www.readbyqxmd.com/read/28636496/the-genus-pulveroboletus-boletaceae-boletales-in-china
#3
Nian-Kai Zeng, Zhi-Qun Liang, Li-Ping Tang, Yan-Chun Li, Zhu L Yang
Species of Pulveroboletus (Boletaceae, Boletales) in China are investigated on the basis of morphology and molecular phylogenetic analyses of DNA sequences from nuc rDNA region encompassing the internal transcribed spacers 1 and 2, along with the 5.8S rDNA (ITS) and nuc 28S rDNA D1-D2 domains (28S) and sequences from the translation elongation factor 1-α gene (TEF1). Nine species are recognized in the country, three of them are described as new: P. flaviscabrosus, P. rubroscabrosus, and P. subrufus, five of them are previous described taxa: P...
May 17, 2017: Mycologia
https://www.readbyqxmd.com/read/28634866/differential-chromosomal-organization-between-saguinus-midas-and-saguinus-bicolor-with-accumulation-of-differences-the-repetitive-sequence-dna
#4
Dayane Martins Barbosa Serfaty, Natália Dayane Moura Carvalho, Maria Claudia Gross, Marcelo Gordo, Carlos Henrique Schneider
Saguinus is the largest and most complex genus of the subfamily Callitrichinae, with 23 species distributed from the south of Central America to the north of South America with Saguinus midas having the largest geographical distribution while Saguinus bicolor has a very restricted one, affected by the population expansion in the state of Amazonas. Considering the phylogenetic proximity of the two species along with evidence on the existence of hybrids between them, as well as cytogenetic studies on Saguinus describing a conserved karyotypic macrostructure, we carried out a physical mapping of DNA repeated sequences in the mitotic chromosome of both species, since these sequences are less susceptible to evolutionary pressure and possibly perform an important function in speciation...
June 20, 2017: Genetica
https://www.readbyqxmd.com/read/28633900/analytical-and-clinical-performance-of-a-chikungunya-qrt-pcr-for-central-and-south-america
#5
Thomas Edwards, Leticia Del Carmen Castillo Signor, Christopher Williams, Clément Larcher, Mauricio Espinel, Jane Theaker, Evelin Donis, Luis E Cuevas, Emily R Adams
Chikungunya was introduced into the Americas in 2015 causing a pandemic across the continent. Testing during the acute phase of infection relies on qRT-PCR, but available assays have a number of limitations. A qRT-PCR assay specific to the chikungunya E1 gene was designed using sequence data from contemporary strains. A probit analysis established the 95% limit of detection as 19.6 copies per reaction. We compared the assay with a US Centers for Disease Control (CDC) chikungunya qRT-PCR as the reference standard...
June 8, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28631324/recent-origin-and-rapid-speciation-of-neotropical-orchids-in-the-world-s-richest-plant-biodiversity-hotspot
#6
Oscar Alejandro Pérez-Escobar, Guillaume Chomicki, Fabien L Condamine, Adam P Karremans, Diego Bogarín, Nicholas J Matzke, Daniele Silvestro, Alexandre Antonelli
The Andean mountains of South America are the most species-rich biodiversity hotspot worldwide with c. 15% of the world's plant species, in only 1% of the world's land surface. Orchids are a key element of the Andean flora, and one of the most prominent components of the Neotropical epiphyte diversity, yet very little is known about their origin and diversification. We address this knowledge gap by inferring the biogeographical history and diversification dynamics of the two largest Neotropical orchid groups (Cymbidieae and Pleurothallidinae), using two unparalleled, densely sampled orchid phylogenies (including more than 400 newly generated DNA sequences), comparative phylogenetic methods, geological and biological datasets...
July 2017: New Phytologist
https://www.readbyqxmd.com/read/28630294/mercury-evidence-for-pulsed-volcanism-during-the-end-triassic-mass-extinction
#7
Lawrence M E Percival, Micha Ruhl, Stephen P Hesselbo, Hugh C Jenkyns, Tamsin A Mather, Jessica H Whiteside
The Central Atlantic Magmatic Province (CAMP) has long been proposed as having a causal relationship with the end-Triassic extinction event (∼201.5 Ma). In North America and northern Africa, CAMP is preserved as multiple basaltic units interbedded with uppermost Triassic to lowermost Jurassic sediments. However, it has been unclear whether this apparent pulsing was a local feature, or if pulses in the intensity of CAMP volcanism characterized the emplacement of the province as a whole. Here, six geographically widespread Triassic-Jurassic records, representing varied paleoenvironments, are analyzed for mercury (Hg) concentrations and Hg/total organic carbon (Hg/TOC) ratios...
June 19, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28630189/in-vitro-activity-of-delafloxacin-and-microbiological-response-against-fluoroquinolone-susceptible-and-non-susceptible-s-aureus-isolates-from-two-phase-3-studies-of-acute-bacterial-skin-and-skin-structure-infections-absssi
#8
S McCurdy, L Lawrence, M Quintas, L Woosley, R Flamm, C Tseng, S Cammarata
Delafloxacin is an investigational anionic fluoroquinolone antibiotic with broad spectrum in vitro activity, including Gram-positive organisms, Gram-negative organisms, atypical organisms, and anaerobes. The in vitro activity of delafloxacin and percent microbiological response in subjects infected with fluoroquinolone susceptible and non-susceptible S. aureus isolates was determined from two global Phase 3 studies of delafloxacin versus vancomycin plus aztreonam in ABSSSI. Patients were enrolled in 23 countries predominately in the US but also Eastern Europe, South America and Asia...
June 19, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28628442/phylogeography-of-burkholderia-pseudomallei-isolates-western-hemisphere
#9
Jay E Gee, Christopher A Gulvik, Mindy G Elrod, Dhwani Batra, Lori A Rowe, Mili Sheth, Alex R Hoffmaster
The bacterium Burkholderia pseudomallei causes melioidosis, which is mainly associated with tropical areas. We analyzed single-nucleotide polymorphisms (SNPs) among genome sequences from isolates of B. pseudomallei that originated in the Western Hemisphere by comparing them with genome sequences of isolates that originated in the Eastern Hemisphere. Analysis indicated that isolates from the Western Hemisphere form a distinct clade, which supports the hypothesis that these isolates were derived from a constricted seeding event from Africa...
July 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28625364/semi-quantitative-models-for-identifying-potent-and-selective-transthyretin-amyloidogenesis-inhibitors
#10
Stephen Connelly, David E Mortenson, Sungwook Choi, Ian A Wilson, Evan T Powers, Jeffery W Kelly, Steven M Johnson
Rate-limiting dissociation of the tetrameric protein transthyretin (TTR), followed by monomer misfolding and misassembly, appears to cause degenerative diseases in humans known as the transthyretin amyloidoses, based on human genetic, biochemical and pharmacologic evidence. Small molecules that bind to the generally unoccupied thyroxine binding pockets in the native TTR tetramer kinetically stabilize the tetramer, slowing subunit dissociation proportional to the extent that the molecules stabilize the native state over the dissociative transition state-thereby inhibiting amyloidogenesis...
May 26, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28624873/short-communication-first-report-of-nematodes-parasitizing-the-four-eyed-fish-anableps-anableps-pisces-cyprinodontiformes
#11
Juliana Souza Ribeiro, Francisco Carlos Rodrigues de Oliveira, Nicole Brand Ederli
The genus Anableps is composed of species Anableps anableps, Anableps dowi, and Anableps microlepis. These fishes are tropical and usually live on the surface of brackish water, being popularly known as four-eyed-fishes due to the presence of prominent eyes and a pupil split horizontally. A. anableps and A. microlepis are considered as sister species that live in sympatry in South America. A. dowi, however, is restricted to the Pacific Ocean (Central America) and is considered the most primitive species of this genus...
June 17, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28623502/molecular-and-morphological-evidence-for-nine-species-in-north-american-australapatemon-sudarikov-1959-a-phylogeny-expansion-with-description-of-the-zygocercous-australapatemon-mclaughlini-n-sp
#12
Michelle A Gordy, Sean A Locke, Timothy A Rawlings, Angela R Lapierre, Patrick C Hanington
Zygocercous (aggregating) cercarial larvae were recently discovered emerging from a physid snail during a molecular survey of cercariae from molluscs in lakes in central Alberta, Canada. This manuscript delves into the characterization of these cercariae through morphological and molecular techniques and provides the first genetic information for a zygocercous larval trematode. Analyses of cytochrome c oxidase I of mitochondrial DNA and two partial regions of nuclear ribosomal DNA sequences revealed the zygocercous cercariae to belong to the genus Australapatemon Sudarikov, 1959...
June 16, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28622346/flavivirus-and-filovirus-evoprinters-new-alignment-tools-for-the-comparative-analysis-of-viral-evolution
#13
Thomas Brody, Amarendra S Yavatkar, Dong Sun Park, Alexander Kuzin, Jermaine Ross, Ward F Odenwald
BACKGROUND: Flavivirus and Filovirus infections are serious epidemic threats to human populations. Multi-genome comparative analysis of these evolving pathogens affords a view of their essential, conserved sequence elements as well as progressive evolutionary changes. While phylogenetic analysis has yielded important insights, the growing number of available genomic sequences makes comparisons between hundreds of viral strains challenging. We report here a new approach for the comparative analysis of these hemorrhagic fever viruses that can superimpose an unlimited number of one-on-one alignments to identify important features within genomes of interest...
June 16, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28618980/evaluating-the-care-cascade-after-antiretroviral-therapy-initiation-in-latin-america
#14
Marcelo J Wolff, Claudia P Cortes, Fernando A Mejìa, Denis Padgett, Pablo Belaunzarán-Zamudio, Beatriz Grinsztejn, Mark J Giganti, Catherine C McGowan, Peter F Rebeiro
Accelerating antiretroviral therapy (ART) administration, improving retention, and achieving viral suppression in low- and middle-income countries must be prioritized. We evaluated trends and disparities in these milestones in a large Latin American cohort. Adults starting ART (ARTstart) from 2003 to 2014 at Caribbean, Central, and South America network for HIV epidemiology sites were assessed for care cascade outcomes: CD4 cell count >200 cells/mm(3) at ARTstart; retention (≥1 visit at one year after ARTstart); viral suppression (≥1 HIV-1 RNA <200 copies/ml at one year after ARTstart)...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28617719/guillain-barr%C3%A3-syndrome-and-zika-virus-outbreaks
#15
Osvaldo J M Nascimento, Ivan R F da Silva
PURPOSE OF REVIEW: Arboviruses have been associated with central and peripheral nervous system injuries, in special the flaviviruses. Guillain-Barré syndrome (GBS), transverse myelitis, meningoencephalitis, ophthalmological manifestations, and other neurological complications have been recently associated to Zika virus (ZIKV) infection. In this review, we aim to analyze the epidemiological aspects, possible pathophysiology, and what we have learned about the clinical and laboratory findings, as well as treatment of patients with ZIKV-associated neurological complications...
June 14, 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/28615353/discovery-of-the-fossil-otter-enhydritherium-terraenovae-carnivora-mammalia-in-mexico-reconciles-a-palaeozoogeographic-mystery
#16
Z Jack Tseng, Adolfo Pacheco-Castro, Oscar Carranza-Castañeda, José Jorge Aranda-Gómez, Xiaoming Wang, Hilda Troncoso
The North American fossil otter Enhydritherium terraenovae is thought to be partially convergent in ecological niche with the living sea otter Enhydra lutris, both having low-crowned crushing teeth and a close association with marine environments. Fossil records of Enhydritherium are found in mostly marginal marine deposits in California and Florida; despite presence of very rich records of fossil terrestrial mammals in contemporaneous localities inland, no Enhydritherium fossils are hitherto known in interior North America...
June 2017: Biology Letters
https://www.readbyqxmd.com/read/28614469/assessing-the-feasibility-of-the-healthy-life-in-suriname-study-using-advanced-hemodynamics-to-evaluate-cardiovascular-risk
#17
Jet Q Aartman, Frederieke S Diemer, Fares A Karamat, Evelien Bohte, Sergio M Baldew, Ameerani V Jarbandhan, Gert A van Montfrans, Glenn P Oehlers, Lizzy M Brewster
Objectives: To determine the feasibility of assessing population cardiovascular risk with advanced hemodynamics in the Healthy Life in Suriname (HELISUR) study. Methods: This was a preliminary study conducted in May - June 2012 using the Technical-Economic-Legal-Operational-Scheduling (TELOS) method to assess the feasibility of the HELISUR-a large-scale, cross-sectional population study of cardiovascular risk factors and disease in Suriname. Suriname, a middle-income country in South America with a population of mostly African and Asian ethnicity, has a high risk of cardiovascular disease...
June 8, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28614394/first-report-of-naturally-infected-aedes-aegypti-with-chikungunya-virus-genotype-ecsa-in-the-americas
#18
André Luis Costa-da-Silva, Rafaella Sayuri Ioshino, Vivian Petersen, Antonio Fernando Lima, Marielton Dos Passos Cunha, Michael R Wiley, Jason T Ladner, Karla Prieto, Gustavo Palacios, Danuza Duarte Costa, Lincoln Suesdek, Paolo Marinho de Andrade Zanotto, Margareth Lara Capurro
BACKGROUND: The worldwide expansion of new emergent arboviruses such as Chikungunya and Zika reinforces the importance in understanding the role of mosquito species in spreading these pathogens in affected regions. This knowledge is essential for developing effective programs based on species specificity to avoid the establishment of endemic transmission cycles sustained by the identified local vectors. Although the first autochthonous transmission of Chikungunya virus was described in 2014 in the north of Brazil, the main outbreaks were reported in 2015 and 2016 in the northeast of Brazil...
June 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28614106/positive-patch-test-reactions-to-essential-oils-in-consecutive-patients-results-from-north-america-and-central-europe
#19
Erin M Warshaw, Kathryn A Zug, Donald V Belsito, Joseph F Fowler, Joel G DeKoven, Denis Sasseville, Howard I Maibach, C G Toby Mathias, Vincent A DeLeo, James S Taylor, Anthony F Fransway, James G Marks, Melanie D Pratt, Matthew J Zirwas, Johannes Geier, Wolfgang Uter
BACKGROUND: Synthetic fragrances and natural essential oils (EOs) are used in perfumery and found in various cosmetics. Essential oils are also increasingly used to promote wellness. In previous studies, the sensitization potential of some EOs has been identified; however, the current prevalence of sensitivity is largely unknown. OBJECTIVES: The aim of this study was to determine frequency of positive patch-test reactions to EOs tested in the baseline series, along with 3 fragrance markers (FMs) (fragrance mix I, fragrance mix II, and Myroxylon pereirae), in consecutive patients in the US/Canadian North American Contact Dermatitis Group (NACDG) (2009-2014) and the central European, trinational Information Network of Departments of Dermatology (IVDK) (2010-2014)...
June 13, 2017: Dermatitis
https://www.readbyqxmd.com/read/28610183/melittofauna-and-other-potential-pollinators-in-wetland-and-uplands-in-south-central-nebraska-insecta-apoidea
#20
Cynthia N Park, Lisa M Overall, Loren M Smith, Ted Lagrange, Scott McMurry
Our objective was to document potential wild pollinating insects in south central Nebraska. This intensively cultivated region is known as the Rainwater Basin and contains some of the most endangered wetland systems in North America. We used blue vane traps to passively collect insects and insect nets to actively collect on flowering plants from April through October in 2014 and 2015. Habitat types included playa wetlands, adjacent mixed and tallgrass prairies, and agricultural fields. Over 112,000 insects were collected; Hymenoptera represented 78% of the total, and the families Apidae and Halictidae comprised 99% of the total melittofauna...
March 10, 2017: Zootaxa
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